v-sis Oncogenes
Genes, PDGFB
c-sis Genes
sis Genes
v-sis Genes
sis Oncogene
Genes, sis
c-sis Proto-Oncogenes

Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long arm of chromosome 22.


Cilazapril, (S*)-Isomer
Cilazapril Monohydrate
Cilazapril Hydrate
Cilazapril Anhydrous
Inhibace
Cilazapril Monohydrobromide
Ro 31-2848
Cilazapril, Anhydrous
Cilazapril
Ro-31-2848

One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS (ACE inhibitors) used for hypertension. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat.


Manipulation, Chiropractic
Spinal Adjustment, Chiropractic
Chiropractic Adjustment

Procedures used by chiropractors to treat neuromusculoskeletal complaints.


Cholesterol, HDL3
Cholesterol, HDL2
HDL3 Cholesterol
Cholesterol, HDL
HDL2 Cholesterol
HDL(2) Cholesterol
alpha-Lipoprotein Cholesterol
High Density Lipoprotein Cholesterol
HDL Cholesterol
HDL(3) Cholesterol

Cholesterol which is contained in or bound to high-density lipoproteins (HDL), including CHOLESTEROL ESTERS and free cholesterol.


Ciliary Photoreceptors
Ciliary Photoreceptor Cells
Photoreceptor Cells
Rhabdomeric Photoreceptor Cells
Rhabdomeric Photoreceptors

Specialized cells that detect and transduce light. They are classified into two types based on their light reception structure, the ciliary photoreceptors and the rhabdomeric photoreceptors with MICROVILLI. Ciliary photoreceptor cells use OPSINS that activate a PHOSPHODIESTERASE phosphodiesterase cascade. Rhabdomeric photoreceptor cells use opsins that activate a PHOSPHOLIPASE C cascade.


Vaccines, Typhoid
Typhoid Vaccine
Paratyphoid Vaccine
Typhoid-Paratyphoid Vaccines
Vaccines, Paratyphoid

Vaccines used to prevent TYPHOID FEVER and/or PARATYPHOID FEVER which are caused by various species of SALMONELLA. Attenuated, subunit, and inactivated forms of the vaccines exist.


Complementary Therapies
Medicine, Complementary
Complementary Medicine
Therapy, Complementary
Alternative Therapies
Medicine, Alternative
Alternative Medicine
Therapy, Alternative

Therapies are termed as Alternative when used instead of conventional treatment.


Locust, Black
Robinia pseudoacacia
Robinia

A plant genus of the family FABACEAE that contains linarin (acaciin) and LECTINS.


Embryonal Carcinoma Stem Cells
Embryonal Carcinoma Cells
Teratocarcinoma Stem Cells
F9 Embryonal Carcinoma Cells
F9 Teratocarcinoma Stem Cells

The malignant stem cells of TERATOCARCINOMAS, which resemble pluripotent stem cells of the BLASTOCYST INNER CELL MASS. The EC cells can be grown in vitro, and experimentally induced to differentiate. They are used as a model system for studying early embryonic cell differentiation.


Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer

Pachycarpine Sulfate (1:1), Pentahydrate, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer

Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer

A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.


Neoplasms, Perivascular Epithelioid Cell

PEComas of the falciform ligament / ligamentum teres.


Protein Phosphatase 1, Catalytic Subunit, gamma2 Isoform

Protein Serine-Threonine Phosphatase 1 beta

Type 1 Serine Threonine Protein Phosphatase

Protein Phosphatase 1, Inhibitory Subunit

Protein Phosphatase 1, Catalytic Subunit, alpha Isoform

Protein Phosphatase 1, Regulatory Subunit

Protein-Serine-Threonine Phosphatase 1 beta

Protein Phosphatase 1, Catalytic Subunit, beta Isoform

Protein Phosphatase 1, Catalytic Subunit, gamma1 Isoform

Protein Phosphatase 1, Catalytic Subunit, gamma Isoform

Protein Phosphatase 1, Catalytic Subunit, delta Isoform

A eukayrotic protein serine-threonine phosphatase subtype that dephosphorylates a wide variety of cellular proteins. The enzyme is comprised of a catalytic subunit and regulatory subunit. Several isoforms of the protein phosphatase catalytic subunit exist due to the presence of multiple genes and the alternative splicing of their mRNAs. A large number of proteins have been shown to act as regulatory subunits for this enzyme. Many of the regulatory subunits have additional cellular functions.


Nandinia binotata
Nandiniidae
African Palm Civet

A family in the suborder Feliformia, order CARNIVORA, comprising one genus Nandinia binotata.


Lactase-Phlorizin Hydrolase
Glycosylceramidase
Phloretin-Glucosidase
Lactase-Glycosylceramidase
Phlorizin Hydrolase
Glycosyl Ceramidase

A multifunctional protein that contains two enzyme domains. The first domain (EC 3.2.1.62) hydrolyzes glycosyl-N-acylsphingosine to a sugar and N-acylsphingosine. The second domain (EC 3.2.1.108) hydrolyzes LACTOSE and is found in the intestinal brush border membrane. Loss of activity for this enzyme in humans results in LACTOSE INTOLERANCE.


Hypertrophic Osteoarthropathy, Primary, Autosomal Dominant

Familial Idiopathic Osteoarthropathy Of Childhood

Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive

Primary Hypertrophic Osteoarthropathy, Autosomal Dominant

A condition chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, SEBORRHEA; HYPERHIDROSIS; periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in the male, and is usually first evident during adolescence. Inheritance is primarily autosomal recessive, but an autosomal dominant form exists.


Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin

A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.


Burkitt's Tumor
Burkitt Cell Leukemia
Burkitt's Lymphoma
African Lymphoma
Leukemia, Lymphocytic, L3
Burkitt Leukemia
Burkitt Tumor
Lymphocytic Leukemia, L3
Lymphoma, Burkitt
Leukemia, Lymphoblastic, Burkitt-Type
Burkitt's Leukemia
Burkitt Lymphoma

A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.


Devices, Medical
Equipment
Medical Device
Apparatus and Instruments
Supplies
Inventories
Equipment and Supplies
Medical Devices
Devices
Device, Medical

Expendable and nonexpendable equipment, supplies, apparatus, and instruments that are used in diagnostic, surgical, therapeutic, scientific, and experimental procedures.


Leishmania infantum chagasi
Leishmania chagasi subsp. Chagasi
Leishmania leishmania infantum
Leishmania chagasi
Leishmania donovani chagasi
Leishmania infantum
Leishmania donovani infantum
Leishmania (Leishmania) chagasi
Leishmania (Leishmania) infantum
Leishmania chagasi chagasi

An isolate that is genetically identical to Leishmania infantum. It is the etiologic agent of LEISHMANIASIS, VISCERAL in the Americas.


Averrhoa bilimbi
Carambola Tree
Averrhoa carambola
Starfruit Tree
Averrhoa
Cucumber Tree

Tropical trees in the family Oxalidaceae


Khloditan Mytotan Chloditan Chlodithane Mitotane o,p-DDD Lysodren ortho,para-DDD

A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.


Adhesive Tape, Surgical
Adhesive Surgical Tape
Skin Tape
Surgical Tape

A flat, flexible strip of material used to cover or fasten together damaged tissue.


Rural Development
Development Planning
Development Plans
Community Development
Social Planning

A systematic process for evaluating and identifying specific needs in the community and the implementation of practical steps for meeting those needs and improving quality of life.


Localized Pigmented Villonodular Synovitis

Localized Giant Cell Tumor of the Tendon Sheath

A tumor arising in the SYNOVIAL MEMBRANE; SYNOVIAL BURSA; or TENDON sheath. It is characterized by OSTEOCLAST-like GIANT CELLS; FOAM CELLS; pigmented HEMOSIDERIN-laden MACROPHAGES and inflammatory infiltrate. It is classified either as diffuse or localized tenosynovitis.


Wild Celery
Celeriac
Apium graveolens var. dulce
Apium
Celery
Apium graveolens
Apium graveolens var. rapaceum

A plant species of the family APIACEAE. The stalks are a food source.


Bioluminescent Measurements
Bioluminescent Assays
Phosphorescent Assays
Chemiluminescent Measurements
Chemiluminescence Measurements
Luminescent Techniques
Phosphorescent Measurements
Chemiluminescent Assays
Luminescent Assays
Luminescent Measurements
Phosphorescence Measurements
Luminescence Measurements
Chemoluminescence Measurements
Bioluminescence Measurements

Measurements of light resulting from CHEMILUMINESCENCE.


Ulex jussiaei
Ulex eulopeus
Ulex europeans
Ulex europaeus
Ulex europus
Ulex
Ulex europaes
Ulex europeaus
Ulex europhaeus
Gorse, Common
Ulex europeus
Ulex europoeus
Gorse, European
Ulex euroapaeus

A plant species that contains Ulex europaeus lectins (gorse agglutinin).


Methenamine Silver
Methenamine
Hexamethylenetetramine
Silver Methenamine
Aminoform
Hexamine
Urotropin
Hexamine Silver

An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)


Omnii-Med
Tin Difluoride
Cav-X
Tin Fluorides
Stannic Fluoride
Omnii-Gel
Tin Tetrafluoride
Gel-Kam
Gel-Tin
Fluoristan
Stanimax
Floran
Stannous Fluoride

Inorganic fluorides of tin. They include both stannic fluoride (tin tetrafluoride) and stannous fluoride (tin difluoride). The latter is used in the prevention of dental caries.


Red Chestnut
Aesculus
Horse Chestnuts
Common Horse Chestnut
Buckeyes
Aesculus hippocastanum

A plant genus of the family HIPPOCASTANACEAE (or SAPINDACEAE by some) that contains antimicrobial protein 1 and escin. A. hippocastanum is used in folk medicine for treating chronic venous insufficiency.


Alloenzymes Allozymes Isoenzymes Isozymes

Isoenzymes that are generated by different alleles of the same gene.


Palliative Surgery
Palliative Supportive Care
Palliative Care
Surgery, Palliative
Palliative Treatment
Palliative Therapy
Therapy, Palliative

Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed)


A selective serotonin uptake inhibitor that is used in the treatment of depression.


Geiger-Mueller Counter Tube
Radiometry
Radiation Counter
Geiger-Mueller Counters
Geiger Counter
Radiation Dosimetry
Dosimetry, Radiation
Nuclear Track Detection
Geiger-Mueller Probe
Geiger-Mueller Tube

A radiation counter that uses a radiation-counter tube, operated in the Geiger range, to detect and count ionizing particles. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)


rho-Associated Coiled-Coil Containing Protein Kinase 2

rho-Associated Coiled-Coil Containing Protein Kinase 1

A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.


SCN Neurons
Suprachiasmatic Nuclei Neurons
SCN Cells
Suprachiasmatic Nucleus Cells
Suprachiasmatic Nucleus Neurons


Iris Atrophy with Corneal Edema and Glaucoma

A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.


The reallocation of beds from one type of care service to another, as in converting acute care beds to long term care beds.


Cryptic Splice Sites
5' Splice Site
RNA Splice Sites
Splice Acceptor Site
Alternative Splice Sites
Splice Donor Site
3' Splice Site

Nucleotide sequences located at the ends of EXONS and recognized in pre-messenger RNA by SPLICEOSOMES. They are joined during the RNA SPLICING reaction, forming the junctions between exons.


A mixture of related phosphoproteins occurring in milk and cheese. The group is characterized as one of the most nutritive milk proteins, containing all of the common amino acids and rich in the essential ones.


Echinoidea
Sand-Dollar
Sand Dollars
Sea Urchins
Clypeasteroida


Pathological Waste
Medical Waste
Waste, Medical
Waste, Pathological

Blood, mucus, tissue removed at surgery or autopsy, soiled surgical dressings, and other materials requiring special disposal procedures.


American Pennyroyal, False
American False Pennyroyal
Melissa pulegioides
Hedeoma
Pennyroyal, American False
Hedeoma pulegioides

A plant genus of the family LAMIACEAE that is closely related to the European pennyroyal (MENTHA PULEGIUM).


Incontinentia Pigmenti Achromians
Ito Syndrome
Pigmentation Disorders
Schamberg Disease
Schamberg's Disease

Diseases affecting PIGMENTATION, including SKIN PIGMENTATION.


Respiratory Physiologic Processes
Respiratory Physiological Phenomenon
Pulmonary Physiological Phenomena
Respiratory Physiological Processes
Pulmonary Physiological Processes
Pulmonary Physiological Phenomenon
Respiratory Physiology
Pulmonary Physiological Process
Physiology, Respiratory
Respiratory Physiological Phenomena
Respiratory Physiological Process
Respiratory Physiological Concepts

Physiological processes and properties of the RESPIRATORY SYSTEM as a whole or of any of its parts.


Phages, T5-like
Enterobacteria phage BF23
Syphoviridae
lambda-Like Phages
Siphoviridae
Phages, lambda-Like
T5-like Phages
lambda-like viruses
T5-like viruses

A tentative species in the genus T5-like PHAGES.


Phenotypic Variation
Between-Subject Variation
Inter-Individual Biological Variation
Biologic Variability, Population
Between-Individual Biological Variation
Biological Variation, Population
Between-Person Biological Variation
Between-Subject Biological Variation
Phenotypic Variability
Between-Person Variation

Differences in measurable biological values, characteristics, or traits, among individuals of a population or between population groups.


Bilevel Continuous Positive Airway Pressure

Nasal Continuous Positive Airway Pressure

Biphasic Continuous Positive Airway Pressure

The administration of CONTINUOUS POSITIVE AIRWAY PRESSURE by the nasal route.


Position Sense
Proprioception
Sense of Position

Sensory functions that transduce stimuli received by proprioceptive receptors in joints, tendons, muscles, and the INNER EAR into neural impulses to be transmitted to the CENTRAL NERVOUS SYSTEM. Proprioception provides sense of stationary positions and movements of one's body parts, and is important in maintaining KINESTHESIA and POSTURAL BALANCE.


Involuntary Smoking
Second Hand Smoke
Secondhand Smoking
Smoking, Passive
Passive Smoking
Environmental Pollution, Tobacco Smoke
Secondhand Smoke
Environmental Smoke Pollution, Tobacco
Tobacco Smoke Pollution
Air Pollution, Tobacco Smoke
Environmental Tobacco Smoke Pollution

Contamination of the air by tobacco smoke.


Oblique Extraocular Muscles
Extraocular Muscles
Oblique Muscle, Superior
Inferior Oblique Extraocular Muscle
Levator Palpebrae Superioris
Oblique Muscle, Inferior
Extraocular Rectus Muscles
Superior Oblique Extraocular Muscle
Rectus Muscles, Extraocular
Oblique Muscles, Extraocular
Musculus Orbitalis
Inferior Oblique Muscles
Superior Oblique Muscle
Oculomotor Muscles

The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris.


Bilevon R
Niclofan
Niclofolan
Bilevon M
Bayer 9015
Distolon
Dertil
Menichlopholan
Distolone
Bayer 3625

Proposed fasciolacide. Synonyms: Dertil; Bilevon; Bay 9015.


NOAEL
No-Observed-Effect Level
Acceptable Daily Intake
Tolerable Daily Intake
No-Observed-Adverse-Effect Level

The daily amount of chemical that can be ingested, which during an entire lifetime appears to be without appreciable health risk. The acceptable daily intake values can be calculated from NO-OBSERVED-ADVERSE-EFFECT LEVEL values.


Smartglasses
Head Mounted Display
Head Worn Display
Google Glass
Smart Glasses
Head Up Display

Computerized eyewear with multiple technological applications for advanced computing and interoperability. Smart glasses are optimized to facilitate information and data access, capture, display, transfer, and manipulation.


Closed Ecologic Life Support Systems
CELSS
Closed Ecological Systems
Breadboard Project
Ecological Systems, Closed
Life Support Systems, Regenerative
Sealed Cabin Ecology

Systems that provide for the maintenance of life in an isolated living chamber through reutilization of the material available, in particular, by means of a cycle wherein exhaled carbon dioxide, urine, and other waste matter are converted chemically or by photosynthesis into oxygen, water, and food. (NASA Thesaurus, 1988)


Rehmannia glutinosa
Foxglove, Chinese
Rehmannia

A plant genus of the family Rehmanniaceae. Members contain catapol, rehmannin and ALKALOIDS.


Infusion Site Adverse Reaction
Injection Site Adverse Event
Infusion Site Reaction
Injection Site Reaction
Injection Site Event
Infusion Site Adverse Event

Adverse reactions that occur initially at the site of injection or infusion. Milder type is confined to a local allergic flare reaction. A more severe reaction is caused by extravasation of VESICANTS from the blood vessel at the site of injection and can cause damage to the surrounding tissue. In tumor flare reaction symptoms involve well beyond the injection site such as an increase in the tumor size and tumor markers levels, bone pain, and HYPERCALCEMIA.


Multihospital Systems
Multi-Hospital Systems
Multi-Institutional System
Multi-Institutional Systems
System, Multi-Hospital
System, Multi-Institutional
Systems, Multi-Institutional

Institutional systems consisting of more than one health facility which have cooperative administrative arrangements through merger, affiliation, shared services, or other collective ventures.


Potassium Clavulanate
BRL-14151
Clavulanic Acid, Monosodium Salt
Sodium Clavulanate
MM-14151
Clavulanic Acid, Monopotassium Salt
Clavulanic Acid
Clavulanate Potassium
Clavulanate

A beta-lactam antibiotic produced by the actinobacterium Streptomyces clavuligerus. It is a suicide inhibitor of bacterial beta-lactamase enzymes. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.


Acute Necrotizing Encephalitis, Herpetic

Meningoencephalitis, Herpes Simplex Virus

An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)


Equivalence Trials as Topic
NonInferiority Trials as Topic
Non-Inferiority Trials as Topic
Superiority Trial as Topic

Works about trials that aim to show a new treatment is no less effective than the standard treatment.


Hematologic Malignancies
Hematological Malignancies
Neoplasms, Hematologic
Hematopoietic Neoplasms
Hematologic Malignancy
Hematologic Neoplasms
Neoplasms, Hematopoietic
Malignancies, Hematologic
Malignancy, Hematologic
Hematopoietic Malignancies
Hematological Neoplasms

Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.


Transfer RNA
Transfer RNA, Suppressor
Suppressor Transfer RNA
tRNA
RNA, Transfer
RNA, Transfer, Suppressor

The small RNA molecules, 73-80 nucleotides long, that function during translation (TRANSLATION, GENETIC) to align AMINO ACIDS at the RIBOSOMES in a sequence determined by the mRNA (RNA, MESSENGER). There are about 30 different transfer RNAs. Each recognizes a specific CODON set on the mRNA through its own ANTICODON and as aminoacyl tRNAs (RNA, TRANSFER, AMINO ACYL), each carries a specific amino acid to the ribosome to add to the elongating peptide chains.


Anti-Human Globulin Complement-Dependent Cytotoxicity Tests

Cytotoxicity Tests, Anti-Human Globulin Complement-Dependent

Anti Human Globulin Complement Dependent Cytotoxicity Tests

The demonstration of the cytotoxic effect on a target cell of a lymphocyte, a mediator released by a sensitized lymphocyte, an antibody, or complement.


Array-Based Comparative Genomic Hybridization

A method for comparing two sets of chromosomal DNA by analyzing differences in the copy number and location of specific sequences. It is used to look for large sequence changes such as deletions, duplications, amplifications, or translocations.


Viral Matrix Proteins
Viral M Protein
Viral Membrane Proteins
Membrane Proteins, Viral
Viral M Proteins

Proteins associated with the inner surface of the lipid bilayer of the viral envelope. These proteins have been implicated in control of viral transcription and may possibly serve as the "glue" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell.


The acetate ester of cortisone that is used mainly for replacement therapy in adrenocortical insufficiency and  in the treatment of many allergic and inflammatory disorders.


Ultradian Cycles
Ultradian Rhythm
Ultradian Cycle

A biological rhythm with a period shorter than 24 hours.


Isradipine, (S)-Isomer
Lomir
PN 205-034
PN-205-033
PN-205-034
Dynacirc
Isradipine
Isradipine, (+-)-Isomer
PN-200-110
Isradipine, (R)-Isomer
PN 205-033
PN 200-110

A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.


Anti-Bacterial Compounds
Bacteriocidal Agents
Antibacterial Agents
Bacteriocides
Antimycobacterial Agents
Antibiotic
Anti-Bacterial Agents
Anti-Mycobacterial Agents
Antibiotics


Protein Footprints
Footprints, Protein
Protein Footprinting

A method for determining points of contact between interacting proteins or binding sites of proteins to nucleic acids. Protein footprinting utilizes a protein cutting reagent or protease. Protein cleavage is inhibited where the proteins, or nucleic acids and protein, contact each other. After completion of the cutting reaction, the remaining peptide fragments are analyzed by electrophoresis.


Tilidin Godecke
Valerone
Tilidate
Valoron
Go-1261
Tilidine Hydrochloride, (+)-Trans
Tilidine Hydrochloride, (+-)-211Trans
Tilidine
Tilidine Hydrochloride

An opioid analgesic used similarly to MORPHINE in the control of moderate to severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1097)


Chromatin Modeling
Chromatin Disassembly
Chromatin Assembly and Disassembly
Chromatin Assembly
Chromatin Remodeling

The mechanisms involved with making the DNA in CHROMATIN more or less accessible to transcription machinery.


Mylohyoid Ridge
Mandible
Mylohyoid Groove

A landmark ridge on the lingual surface of the mandible.


Reparil opino-biomo Escina Flebostasin Fepalitan Eskuzan Escin Aescusan beta-Aescin Opino beta-Escin Aescin Feparil

Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.


Choloxin
D-Thyroxine
Dextrothyroxine
D-T4 Thyroid Hormone
Sodium Dextrothyroxine
Dextrothyroxine Sodium

The dextrorotary isomer of the synthetic THYROXINE.


Neoplasms, Adrenal Gland
Cancer of the Adrenal Gland
Adrenal Gland Neoplasms
Adrenal Gland Cancer
Adrenal Cancer
Adrenal Neoplasm


Familial Porencephalic White Matter Disease

Porencephaly, Type 1, Autosomal Dominant

Cortical malformations characterized by white matter-lined cleft or cyst associated with ISCHEMIA and hemorrhagic insults. Symptoms include delayed growth and development, HYPOTONIA; SEIZURES; SPASTIC HEMIPLEGIA and MACROCEPHALY; MICROCEPHALY; or HYDROCEPHALUS. Mutations in the genes encoding COLLAGEN TYPE IV are associated with familial types.


Abdominal Obesity
Visceral Obesity
Central Obesity
Obesity, Abdominal
Obesity, Visceral

Obesity due to excessive deposition of INTRA-ABDOMINAL FAT in the abdominal VISCERA and OMENTUM.


Surgical Procedures, Esophagoscopic
Esophagoscopic Surgical Procedures
Esophagoscopy
Esophagoscopic Surgery
Surgery, Esophagoscopic

Endoscopic examination, therapy or surgery of the esophagus.


Vegetative State
Persistent Vegetative State
Post-Traumatic Unawareness State
PVS (Persistent Vegetative State)
Persistent Unawareness State
Post-Comatose Unawareness State
Post-Traumatic Vegetative State
Minimally Conscious State
Posttraumatic Unawareness State
Prolonged Post-Traumatic Unawareness
Permanent Vegetative State
Vegetative State, Persistent
Transient Vegetative State
Postcomatose Unawareness State

Vegetative state refers to the neurocognitive status of individuals with severe brain damage, in whom physiologic functions (sleep-wake cycles, autonomic control, and breathing) persist, but awareness (including all cognitive function and emotion) is abolished.


SDF-1alpha
Chemokine CXCL12
Stromal Cell-Derived Factor-1alpha
Pre-B-Cell Growth-Stimulating Factor
CXCL12 Chemokine
Chemokine (C-X-C Motif) Ligand 12
Stromal Cell-Derived Factor-1beta
Stromal Cell-Derived Factor 1
SDF-1beta
SDF1-3'A


Scars Scarring Cicatrix Cicatrization Scar

The formation of fibrous tissue in the place of normal tissue during the process of WOUND HEALING. It includes scar tissue formation occurring in healing internal organs as well as in the skin after surface injuries.


Allele Frequency
Genetic Equilibrium
Equilibrium, Genetic
Gene Frequency

The proportion of one particular in the total of all ALLELES for one genetic locus in a breeding POPULATION.


Vindesine Sulfate
Compound 112531
Vindesine
Eldisine
Enison
NSC-245467
Desacetylvinblastine Amide
Vindesin

Vinblastine derivative with antineoplastic activity against CANCER. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS).


Hyperbilirubinemia, Hereditary
Hyperbilirubinemia, Rotor Type
Rotor Syndrome

Inborn errors of bilirubin metabolism resulting in excessive amounts of bilirubin in the circulating blood, either because of increased bilirubin production or because of delayed clearance of bilirubin from the blood.


Walruses
Odobenus rosmarus
Walrus
Odobenidae

The family Odobenidae, suborder PINNIPEDIA, order CARNIVORA. It is represented by a single species of large, nearly hairless mammal found on Arctic shorelines, whose upper canines are modified into tusks.


AC 2993 LAR
ITCA 650
Exenatide
Byetta
AC 2993
Bydureon
Exendin-4
Exendin 4
Ex4 Peptide

A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the Gila monster lizard (Heloderma suspectum). Exenatide increases CYCLIC AMP levels in pancreatic acinar cells and acts as a GLUCAGON-LIKE PEPTIDE-1 RECEPTOR (GLP-1) agonist and incretin mimetic, enhancing insulin secretion in response to increased glucose levels; it also suppresses inappropriate glucagon secretion and slows gastric emptying. It is used an anti-diabetic and anti-obesity agent.


Hospital department responsible for the administration of functions and activities pertaining to the delivery of anesthetics.


Cholangitis, Sclerosing
Cholangiitis, Sclerosing
Cholangitis, Primary Sclerosing
Primary Sclerosing Cholangitis
Sclerosing Cholangitis

Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.


Protein Folding Diseases
Protein Folding Disorders
Protein Misfolding Diseases
Proteostasis Deficiencies
Protein Misfolding Disorders
Proteostasis Dysfunctions

Disorders caused by dysfunctions in PROTEIN FOLDING and degradation or clearance of misfolded proteins.


Vitamin B 12
Vitamin B12
Cobalamins
Eritron
Cobalamin
Cyanocobalamin

A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. INTRINSIC FACTOR is important for the assimilation of vitamin B 12.


Genetic Diseases, Inborn
Hereditary Disease
Inborn Genetic Diseases
Genetic Disorders
Genetic Diseases
Single-Gene Defects
Hereditary Diseases

Diseases caused by genetic mutations that are inherited from a parent's genome.


Galanthus nivalis L. is the source of GALANTHAMINE.


Limited Resection Mastectomy
Breast Quadrantectomy
Local Excision Mastectomy
Partial Mastectomy
Mastectomy, Segmental
Lumpectomy
Segmentectomy
Breast-Conserving Surgery
Surgery, Breast-Conserving
Breast Conservation Therapy
Breast-Sparing Surgery

Removal of only enough breast tissue to ensure that the margins of the resected surgical specimen are free of tumor.


Medicine, Preventive
Preventative Care
Preventive Medicine
Preventive Care
Preventative Medicine

A medical specialty primarily concerned with prevention of disease (PRIMARY PREVENTION) and the promotion and preservation of health in the individual.


Materials Failure Analysis
Equipment Failure Analysis
Analysis, Equipment Failure
Analysis, Materials Failure
Prosthesis Failure Analysis
Analysis, Prosthesis Failure

The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.


Dental Periodicals Publishing
Periodicals Publishing, Dental
Journalism, Dental
Publishing, Dental Periodicals
Dental Journalism

Content, management, editing, policies, and printing of dental periodicals such as journals, newsletters, tabloids, and bulletins.


Genitalia, Female
Genitals, Female
Accessory Sex Organs, Female
Sex Organs, Accessory, Female
Reproductive System, Female
Genital Organs, Female

The female reproductive organs. The external organs include the VULVA; BARTHOLIN'S GLANDS; and CLITORIS. The internal organs include the VAGINA; UTERUS; OVARY; and FALLOPIAN TUBES.


DNA Type 2 Topoisomerase
DNA Topoisomerases, Type II
Topoisomerase II
Topoisomerase II beta
Type II DNA Topoisomerase
TOP2B Protein
TOP2A Protein
DNA Topoisomerase (ATP-Hydrolysing)
DNA Topoisomerase II
DNA Topoisomerase II alpha
DNA Topoisomerase II beta
Topoisomerase II alpha

DNA TOPOISOMERASES that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex.


T Cell Leukemia Lymphoma Virus Antigens, Human

Leukemia Lymphoma Virus Antigens, Human T Cell

T-Cell Leukemia-Lymphoma Virus Antigens, Human

Leukemia-Lymphoma Virus Antigens, Human T-Cell

Antigens associated with the DELTARETROVIRUS; HTLV-I ANTIGENS and HTLV-II ANTIGENS belong to this group.


An alpha-2 selective adrenergic agonist used as an antihypertensive agent.


(1R,2S)-1-Benzyl-3-dimethylamino-2-methyl-1-phenylpropyl propionate naphthalene-2-sulphonate monohydrate

(1R,2R)-1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate naphtalene-2-sulfonic acid

A propionate derivative that is used  to suppress coughing.


Cervical Atlas
Ponticulus Posticus
Arcuate Foramen
Kimmerle Anomaly
C1 Vertebra
Ponticulus Posterior of the Atlas
Atlas, Cervical

An anatomical variant of the cervical atlas in which osseous bridges connect posterior superior articular process to the posterior arch thereby covering grooves for the VERTEBRAL ARTERY.


Platycodon
Balloon Flower
Platycodon grandiflorum
Bellflower, Chinese

A plant genus of the family CAMPANULACEAE that contains platycodin and other triterpenoid SAPONINS. It is a constituent of kikyo-to (MEDICINE, KAMPO).


I2S Deficiency
Iduronate 2-Sulfatase Deficiency
Hunter Syndrome Gargoylism
Iduronate Sulfatase Deficiency
Mucopolysaccharidosis 2
Sulfoiduronate Sulfatase Deficiency
Mucopolysaccharidosis Type 2
Mucopolysaccharidosis Type II
Hunter's Syndrome
Gargoylism, Hunter Syndrome
Mucopolysaccharidosis II
Hunter Syndrome

Systemic lysosomal storage disease marked by progressive physical deterioration and caused by a deficiency of L-sulfoiduronate sulfatase. This disease differs from MUCOPOLYSACCHARIDOSIS I by slower progression, lack of corneal clouding, and X-linked rather than autosomal recessive inheritance. The mild form produces near-normal intelligence and life span. The severe form usually causes death by age 15.


Parmeliaceae
Iceland Moss
Cetraria
Cetraria islandica

The largest family of lichen-forming fungi.


Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1

An APOBEC deaminase catalytic subunit of the apolipoprotein B (APOB) MESSENGER RNA (mRNA) editing enzyme complex that is involved in post-transcriptional editing of a CAA codon for GLYCINE to a UAA STOP CODON in the ApoB mRNA. It also functions in CGA (ARGININE) to UGA STOP CODON editing of NEUROFIBROMIN 1 mRNA and EPIGENETIC PROCESSES.


Hyoscyamine Sulfate Anhydrous
Hyoscyamine Sulfate
Hyoscyamine Hydrochloride
Hyoscyamine
Atropine, 3(S)-endo-Isomer
Atropine Sulfate, 3(S)-endo-Isomer
Cytospaz
Anaspaz
Hyoscyamine Hydrobromide


Tunga penetrans
Tunga
Jigger Flea
Sand Flea
Chigoe Flea

A species of burrowing flea that requires a human host or other mammal to reproduce.


Nuclear Receptor Subfamily 1, Group H, Member 3

Nuclear Receptor Subfamily 1, Group H, Member 2

A liver X receptor that is expressed primarily by cells in the liver and other metabolically-active tissues.


Dysglossia
Verbal Fluency Disorders
Dyslalia
Aprosodic Speech
Rhinolalia
Cluttering
Speech Disorders
Aprosodia

Acquired or developmental conditions marked by an impaired ability to comprehend or generate spoken forms of language.


Benzene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.


Clinical Effectiveness
Treatment Outcome
Rehabilitation Outcome
Clinical Efficacy
Patient-Relevant Outcome
Treatment Efficacy
Treatment Effectiveness

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.


Incubators, Infant
Infant Radiant Warmers
Radiant Warmers, Infant

Electrically powered devices that are intended to assist in the maintenance of the thermal balance of infants, principally by controlling the air temperature and humidity in an enclosure. (from UMDNS, 1999)


Cherry, Ground
Ground Cherry
Tomatillo
Physalis

A plant genus of the family SOLANACEAE. Members contain physalin and withangulatin.


Tumor Necrosis Factor Receptor-Associated Peptides and Proteins

Tumor Necrosis Factor Receptor-Associated Factors

TRAF and TNF Receptor-Associated Proteins

A family of genetically conserved signal transducing proteins that bind directly to TUMOR NECROSIS FACTOR RECEPTORS.


Peripheral Nervous System Malignant Neoplasms

Peripheral Nerve Neoplastic Infiltration

Peripheral Nervous System Benign Neoplasms

Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)


Euthanasia, Voluntary
Euthanasia, Active, Voluntary
Voluntary Euthanasia

Active euthanasia of a patient at the patient's request and/or with the patient's consent.


A non-estrogenic contraceptive which is a weak progestin with strong anti-progesterone properties. It is effective if used once a week orally or can also be used in intravaginal devices.


Balanced Anesthesia
Anociassociation
Anocithesia
Anoci-Association

A historical term for a method of anesthesia that used a combination of preanesthetic medication for sedation, local nerve blocking anesthetic at the surgical site, and NITROUS OXIDE inhalation anesthesia.


Lipodystrophy, Familial Partial, Dunnigan Type

Lipodystrophy, Familial, of Limbs and Lower Trunk

Familial Partial Lipodystrophy, Kobberling Type

Lipodystrophy, Familial Partial, Kobberling Type

Lipodystrophy, Familial Partial, Associated With PPARg Mutations

This type can be caused by mutation in the gene encoding PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA.


Allelochemicals Ectohormones Synomones Pheromones Kairomones Semiochemicals Allomones

Chemical substances, excreted by an organism into the environment, that elicit behavioral or physiological responses from organisms of a different species . Perception of these chemical signals may be olfactory or by contact. Allelochemicals are subdivided into several groups depending on the response of the receiver and its adaptive effect to the emitter. They can be allomones, kairomones, or synomones.


FKBP Rotamase
Rapamycin-Binding Proteins
FK-506-Binding Protein
FKBP
FK506 Binding Protein
FK506 Binding Proteins
FK506-Binding Protein
Rapamycin Binding Proteins
Tacrolimus Binding Proteins

A family of immunophilin proteins that bind to the immunosuppressive drugs TACROLIMUS (also known as FK506) and SIROLIMUS. EC 5.2.1.-


Anxiety Disorders
Neuroses, Anxiety
Anxiety Neuroses
Anxiety States, Neurotic


Healthcare Industry
Healthcare Market
Industry, Healthcare
Health Care Sector
Health Care Market
Healthcare Sector
Health Care Industry

Economic sector concerned with the provision, distribution, and consumption of health care services and related products.


Tretoquinol
Tretoquinol-(R)
AQL-208
Trimetoquinol
AQ-110
Tretoquinol Hydrochloride
Tretoquinol-(S) HCl
Tretoquinol Hydrochloride, (S)-Isomer
CV-705
Trimethoquinol
Tetroquinol
Tretoquinol Hydrochloride Anhydrous

An adrenergic beta-agonist used as a bronchodilator agent in asthma therapy.


Sealions
Sea Lions
Zalophus californianus
Sea Lion, California
Zalophus
California Sea Lion

A group comprised of several species of aquatic carnivores in different genera, in the family Otariidae. In comparison to FUR SEALS, they have shorter, less dense hair.


Phentanyl
Duragesic
Fentanest
R-4263
Durogesic
Fentora
Fentanyl
Fentanyl Citrate
Transmucosal Oral Fentanyl Citrate
Sublimaze

A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)


Alpha High Density Lipoprotein Deficiency Disease

High-Density Lipoprotein Deficiency, Tangier Type

High-Density Lipoprotein Deficiency, Type I

High Density Lipoprotein Deficiency, Type 1

High Density Lipoprotein Deficiency, Tangier Type

An autosomal recessively inherited disorder caused by mutation of ATP-BINDING CASSETTE TRANSPORTERS involved in cellular cholesterol removal (reverse-cholesterol transport). It is characterized by near absence of ALPHA-LIPOPROTEINS (high-density lipoproteins) in blood. The massive tissue deposition of cholesterol esters results in HEPATOMEGALY; SPLENOMEGALY; RETINITIS PIGMENTOSA; large orange tonsils; and often sensory POLYNEUROPATHY. The disorder was first found among inhabitants of Tangier Island in the Chesapeake Bay, MD.


Annexin A2, P90 Complex
Annexin A2
Annexin II, P36
Calpactin I
Lipocortin II
Capactin I Heavy Chain
Annexin II
Annexin II, P90 Complex

A 90-KD complex containing two subunits of Annexin A2 and two subunits of S100 FAMILY PROTEIN P11.


Polar Ice Shelf
Sea Ice
Glaciers
Sea Ice Cover
Icebergs
Ice Cover
Marine Glaciers
Ice Sheet

A thick mass of ICE formed over large regions of land; RIVERS; LAKES; ponds; or SEAWATER.


REM Sleep Parasomnias
Sinus Arrest, REM Sleep-Related
Painful Erections, Sleep-Related
Parasomnias, REM Sleep
Sleep-Related Painful Erections
Rapid Eye Movement Sleep Parasomnias
REM Sleep-Related Sinus Arrest
Sleep, REM, Parasomnias

Abnormal behavioral or physiologic events that are associated with REM sleep, including REM SLEEP BEHAVIOR DISORDER.


RNase P
Ribonuclease P
Ribonuclease P, RNA Catalytic Subunit
RNA Catalytic Subunit, Ribonuclease P

An RNA-containing enzyme that plays an essential role in tRNA processing by catalyzing the endonucleolytic cleavage of TRANSFER RNA precursors. It removes the extra 5'-nucleotides from tRNA precursors to generate mature tRNA molecules.


Antineoplastic MAbs
Antineoplastics, Monoclonal Antibody
MAbs, Antineoplastic
Antineoplastic Agents, Immunological
Antineoplastics, Monoclonal Antibodies
Monoclonal Antibodies, Antineoplastic

Monoclonal antibodies that inhibit or prevent the proliferation of NEOPLASMS.


Morbilliform Exanthem
Drug Eruptions
Dermatitis Medicamentosa
Morbilliform Drug Reaction
Dermatitis, Adverse Drug Reaction
Maculopapular Drug Eruption
Maculopapular Exanthem

Dermatoid drug eruption characterized by widespread erythematous macules and papules often associated with a mild fever and itch.


An aminobisphosphonate that inhibits BONE RESORPTION and is used for the treatment of osteolytic lesions, bone pain, and severe HYPERCALCEMIA associated with malignancies.


Australian Race
Aborigines, Australian
Pacific Island Americans
Pacific Islander Americans
Australoid Race
Native Hawaiians
Oceanic Ancestry Group

A group that includes the Australian aborigines and possibly some other remnant populations of Malaysia. (From Molnar, Races, Types, and Ethnic Groups, 1975, p17)


Aminoglycoside 3'-Phosphotransferases (I and II)

Aminoglycoside 3'-Phosphotransferase Type VIII

Aminoglycoside Phosphotransferase Type III

A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.


Aphasia, Progressive
Lichtheim's Sign
Logagnosia
Aphasia, Acquired
Aphasia, Semantic
Aphasia
Logamnesia
Aphasia, Mixed
Aphasia, Post-Ictal
Aphasia, Intellectual
Logasthenia
Dejerine-Lichtheim Phenomenon
Aphasia, Syntactical
Anepia
Dysphasia
Dysphasia, Global
Alogia
Aphasia, Global
Aphasia, Graphomotor
Aphasia, Ageusic
Aphasia, Auditory Discriminatory
Aphasia, Commisural
Aphasia, Post-Traumatic
Aphasia, Functional

A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.


Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)


Wolfberry
Goji Berry Plant
Lycium barbarum
Lycium chinense
Goji Berry
Lycium

A plant genus of the family SOLANACEAE. Members contain CEREBROSIDES and SCOPOLETIN.


Cornified Envelope Proline-Rich Proteins

Small Proline-Rich Cornified Envelope Proteins

A family of low molcular-weight proteins that contain PROLINE-RICH PROTEIN DOMAINS. Members of this family play a role in the formation of an insoluble cornified envelope beneath the plasma membrane of stratified squamous epithelial cells.


Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.


Cyclic-Nucleotide Gated Channel
CNG Channel (Rod)
Cyclic Nucleotide-Gated Cation Channel
Cng Cation Channel
Cyclic Nucleotide-Gated Cation Channels
Cationic Channel Protein (Rod)
Cyclic-Nucleotide Gated Ion Channels

A subgroup of cyclic nucleotide-regulated ION CHANNELS within the superfamily of pore-loop cation channels. They are expressed in OLFACTORY NERVE cilia and in PHOTORECEPTOR CELLS and some PLANTS.


Aortic Aneurysm, Thoracic
Thoracoabdominal Aortic Aneurysm
Aortic Aneurysm, Thoracoabdominal
Aneurysm, Thoracic Aortic

An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.


Carbacholine
Carbamann
Carboptic
Carbamoylcholine
Isopto Carbachol
Carbamylcholine
Carbastat
Carbocholine
Carbachol
Doryl
Jestryl
Miostat

A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.


Nature Therapy
Ecotherapy
Relaxation Therapy
Relaxation Techniques
Therapy, Relaxation
Relaxation Technics

Treatment to improve one's health condition by using techniques that can reduce PHYSIOLOGICAL STRESS; PSYCHOLOGICAL STRESS; or both.


Alcea
Hollyhock
Helicteres
Mansonia
Malvaceae
Sterculiaceae
Waltheria
Mallow Family

The mallow family of the order MALVALES, subclass Dilleniidae, class Magnoliopsida. The common names of hollyhock and mallow are used for several genera of Malvaceae.


Pancreatic D Cells
Somatostatin-Secreting Cells
delta Cells
Gastric D Cells
D Cells
Gastric delta Cells
Pancreatic delta Cells
Somatostatin Cells

Endocrine cells found throughout the GASTROINTESTINAL TRACT and in islets of the PANCREAS. D cells secrete SOMATOSTATIN that acts in both an endocrine and paracrine manner. Somatostatin acts on a variety of tissues including the PITUITARY GLAND; gastrointestinal tract; pancreas; and KIDNEY by inhibiting the release of hormones, such as GROWTH HORMONE; GASTRIN; INSULIN; and RENIN.


Pongamia pinnata
Millettia
Derris indica
Indian Beech Tree
Karumtree
Millettia pinnata

A plant genus of the family FABACEAE. Members contain ISOFLAVONES, some of which show molluscicidal and schistosomicidal activity. Some species of Pongamia have been reclassified to this genus and some to DERRIS.


Microscopy, Confocal
Confocal Laser Scanning Microscopy
Laser Scanning Microscopy
Confocal Microscopy, Scanning Laser
Confocal Microscopy
Laser Microscopy
Laser Scanning Confocal Microscopy
Microscopy, Confocal, Laser Scanning

A light microscopic technique in which only a small spot is illuminated and observed at a time. An image is constructed through point-by-point scanning of the field in this manner. Light sources may be conventional or laser, and fluorescence or transmitted observations are possible.


Air Pollutants
Environmental Air Pollutants
Air Pollutants, Environmental
Environmental Pollutants, Air

Air pollutants which affect environmental conditions.


1-Sar-8-Ala Angiotensin II
Saralasin
Saralasin Acetate, Anhydrous
Angiotensin II, Sar(1)-Ala(8)-
Saralasin Acetate, Hydrated
1-Sarcosine-8-Alanine Angiotensin II
(Sar(1),Ala(8))ANGII
(Sar1,Val5,Ala8)Angiotensin II
Sar-Arg-Val-Tyr-Val-His-Pro-Ala
Saralasin Acetate
Angiotensin II, Sarcosyl(1)-Alanine(8)-

An octapeptide analog of angiotensin II (bovine) with amino acids 1 and 8 replaced with sarcosine and alanine, respectively. It is a highly specific competitive inhibitor of angiotensin II that is used in the diagnosis of HYPERTENSION.


Gluten Proteins
Gluten
Secalins
Hordeins
Hordein
Secalin
Glutelins
Glutens
Glutelin

A gluten protein of BARLEY analogous to GLIADINS of WHEAT.


Iron-Responsive Element Binding Proteins

Proteins that regulate cellular and organismal iron homeostasis. They play an important biological role by maintaining iron levels that are adequate for metabolic need, but below the toxicity threshold.


Narcotic Addiction
Narcotic Dependence
Narcotic-Related Disorders
Narcotic Abuse

Disorders related to or resulting from abuse or misuse of NARCOTICS.


A selective D1 dopamine receptor agonist used primarily as a research tool.


Pancreas Cancer
Cancer of the Pancreas
Neoplasms, Pancreatic
Pancreas Neoplasms
Pancreatic Neoplasms
Cancer of Pancreas
Pancreatic Cancer

Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).


Apomorphine Hydrochloride Anhydrous
Apomorphin-Teclapharm
Britaject
Apomorphine Hydrochloride
Apokinon
Apomorphine Hydrochloride, Anhydrous
Apomorphine Hydrochloride, Hemihydrate
Apomorphine
Apomorphine Chloride

A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.


Information Systems, Hospital
Hospital Information Systems
Multihospital Information Systems
Information System, Multihospital
Information Systems, Multihospital
Multi-Hospital Information Systems
Information System, Hospital

Integrated, computer-assisted systems designed to store, manipulate, and retrieve information concerned with the administrative and clinical aspects of providing medical services within the hospital.


Child Development Deviations
Developmental Delay Disorders
Disabilities, Developmental
Developmental Disabilities
Child Development Disorders, Specific
Child Development Disorders
Development Disorders, Child

Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)


Tanacetum cinerariifolium
Chrysanthemum coccineum
Pyrethum Daisy
Tanacetum coccineum
Pyrethrum
Chrysanthemum cinerariifolium

A plant species of the genus CHRYSANTHEMUM, family ASTERACEAE. The flowers contain PYRETHRINS, cinerolones, and chrysanthemines which are powerful contact insecticides. Most in the old Pyrethrum genus are reclassified to TANACETUM; some to other ASTERACEAE genera.


Neutraceuticals
Food Supplements
Dietary Supplements
Herbal Supplements
Dietary Supplementations
Nutriceuticals
Nutraceuticals
Food Supplementations

A term coined from a contraction of nutrition and pharmaceutical to mean a component of food that has bioactive effects. It is used in marketing and has no regulatory definition.


Cataract
Lens Opacities
Pseudoaphakia
Cataract, Membranous

Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)


Loaches
Catostomidae
Catostomus
Misgurnus
Cypriniformes
Cobitidae
Suckers (Fish)
Catastomus


Conus Venoms
Mollusk Venom
Snail Venoms
Octopus Venom
Snail Venom
Conus Venom
Mollusk Venoms
Octopus Venoms
Mollusc Venoms

Venoms from mollusks, including CONUS and OCTOPUS species. The venoms contain proteins, enzymes, choline derivatives, slow-reacting substances, and several characterized polypeptide toxins that affect the nervous system. Mollusk venoms include cephalotoxin, venerupin, maculotoxin, surugatoxin, conotoxins, and murexine.


Dilcoran
Peritrate
Nirason
Pentaerythritol Tetranitrate
Erinit
Pentalog
Nitrodex
Tetrate

A vasodilator with general properties similar to NITROGLYCERIN but with a more prolonged duration of action. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1025)


Hydrogen Carbonates
Hydrogen Carbonate
Carbonic Acid Ions
Bicarbonates
Bicarbonate Ion
Bicarbonate Ions

Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.


Inhibitors of Cyclin-Dependent Kinase 4 Proteins

Cyclin-Dependent Kinase Inhibitor Proteins

CIP-KIP Cyclin-Dependent Kinase Inhibitors

A family of cell cycle proteins containing ANKYRIN REPEATS that are specific inhibitors of cyclin D-dependent kinases. INK4 proteins bind to CYCLIN-DEPENDENT KINASE 4 and CYCLIN-DEPENDENT KINASE 6. They dissociate cyclin-CDK complexes and regulate a CELL CYCLE checkpoint in early G1 PHASE.


Vascular-Hepatic Type Arginine Vasopressin Receptor

Renal-Type Arginine Vasopressin Receptor

Specific molecular sites or proteins on or in cells to which VASOPRESSINS bind or interact in order to modify the function of the cells. Two types of vasopressin receptor exist, the V1 receptor in the vascular smooth muscle and the V2 receptor in the kidneys. The V1 receptor can be subdivided into V1a and V1b (formerly V3) receptors.


Multinational Aspects
International Relations
Internationality
International Perspectives
Multinational Perspectives
Globalization
International Aspects

Development of increasingly world-wide interdependences.


A plant genus of the family PRIMULACEAE. It can cause CONTACT DERMATITIS. SAPONINS have been identified in the root.


Ventilation, Mechanical
Mechanical Ventilation
Respiration, Artificial

Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).


A thiazolidinedione that functions as a selective agonist for PPAR GAMMA. It improves INSULIN SENSITIVITY in adipose tissue, skeletal muscle, and the liver of patients with TYPE 2 DIABETES MELLITUS.


Technology, Health
Biomedical Technologies
Health Care Technology
Technology, Biomedical
Technology, Health Care
Biomedical Technology
Health Technology

The application of technology to the solution of medical problems.


Transmembrane Electrical Potential Difference

The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).


Education, Nonprofessional
Nonprofessional Education
Education, Parenting
Parenting Education

Education and training outside that for the professions.


Cerebral Concussion
Mild Traumatic Brain Injury
Concussion, Mild
Concussion, Severe
Commotio Cerebri
Concussion, Intermediate
Brain Concussion

A nonspecific term used to describe transient alterations or loss of consciousness following closed head injuries. The duration of UNCONSCIOUSNESS generally lasts a few seconds, but may persist for several hours. Concussions may be classified as mild, intermediate, and severe. Prolonged periods of unconsciousness (often defined as greater than 6 hours in duration) may be referred to as post-traumatic coma (COMA, POST-HEAD INJURY). (From Rowland, Merritt's Textbook of Neurology, 9th ed, p418)


Anticonvulsant Drugs
Anticonvulsive Agents
Anticonvulsive Drugs
Antiepileptic Drugs
Anticonvulsants
Antiepileptic Agents
Antiepileptics

Drugs used to prevent SEIZURES or reduce their severity.


Collagen Type V
Collagen alpha2(V)
Collagen Type V, alpha2 Chain
Type V Procollagen
Collagen alpha1(V)
Collagen Type V, alpha3 Chain
Collagen Type V, alpha2 Subunit
Procollagen Type V
Collagen alpha3(V)
Collagen Type V, alpha1 Subunit
Type V Collagen
Collagen Type V, alpha1 Chain
Collagen Type V, alpha3 Subunit

A fibrillar collagen found widely distributed as a minor component in tissues that contain COLLAGEN TYPE I and COLLAGEN TYPE III. It is a heterotrimeric molecule composed of alpha1(V), alpha2(V) and alpha3(V) subunits. Several forms of collagen type V exist depending upon the composition of the subunits that form the trimer.


MCT Proteins
Pyruvate Transport Protein
Monocarboxylic Acid Transporters
Lactate Translocase
Monocarboxylic Acid Transport Proteins
Erythrocyte Lactate Transporter
Lactate Transporter
Pyruvate Transport Proteins
Erythrocyte Lactate Transporters
Lactate Transport Proteins
Pyr Translocator
Lactate Transport Protein
Monocarboxylic Acid Transport Protein
Monocarboxylate Translocator
Pyruvate Transporter
Pyruvate Carrier

A family of proteins involved in the transport of monocarboxylic acids such as LACTIC ACID and PYRUVIC ACID across cellular membranes.


Sequence Analysis, Peptide
Protein Sequence Analysis
Sequence Analyses, Amino Acid
Sequence Determination, Amino Acid
Sequence Determinations, Amino Acid
Amino Acid Sequence Determination
Amino Acid Sequence Analyses
Amino Acid Sequence Determinations
Peptide Sequence Determination
Sequence Determination, Protein
Sequence Analysis, Amino Acid
Sequence Analysis, Protein
Peptide Sequence Analysis
Amino Acid Sequencing
Amino Acid Sequence Analysis
Protein Sequencing

A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.


A plant genus of the family SAPINDACEAE. Members contain hypoglycins and ackee oil.


Piperoxan
Benodain
Piperoxane
Forneau 933
Benodaine

A benzodioxane alpha-adrenergic blocking agent with considerable stimulatory action. It has been used to diagnose PHEOCHROMOCYTOMA and as an antihypertensive agent.


Hemangioma, Cavernous, Central Nervous System

Central Nervous System Cavernous Hemangioma

Cavernous Hemangioma, Central Nervous System

Cavernous Angioma, Central Nervous System

A vascular anomaly composed of a collection of large, thin walled tortuous VEINS that can occur in any part of the central nervous system but lack intervening nervous tissue. Familial occurrence is common and has been associated with a number of genes mapped to 7q, 7p and 3q. Clinical features include SEIZURES; HEADACHE; STROKE; and progressive neurological deficit.


Genetic Information, Personal
Personal Genetic Information
Genetic Privacy

The protection of genetic information about an individual, family, or population group, from unauthorized disclosure.


Prunus persica (L.) Batsch is the source of peaches.


Behavior
Acceptance Process
Acceptance Processes

The observable response of a man or animal to a situation.


Oreamnos americanus
Ruminants
Goats, Mountain
Ruminantia

A species Oreamnos americanus, but not a true goat, despite its common name. It is more similar to CHAMOIS and gorals rather than GOATS.


Diterpenes, Abietane
Isopimaranes
Abietane Diterpenoids
Totaranes
Abietanes
Totarane Diterpines
Diterpenes, Pimarane
Pimaranes

DITERPENES that are nearly like abietanes but the 13-position has a methyl and an ethyl instead of an isopropyl group.


Coleus forskohli
Plectranthus
Plectranthus barbatus
Coleus forskohlii
Coleus barbatus
Forskohlii

A plant genus of the family LAMIACEAE that contains eudesmane sesquiterpenes and antimicrobial abietane diterpenoids.


Memory, Prospective
Episodic Memory
Prospective Memory
Memory, Episodic
Autobiographical Memory

Dissociable form of episodic memory involving the ability to execute a future intention. (Campbell's Psychiatric Dictionary, 9th ed.)


Surgery, Bronchoscopic
Surgical Procedures, Bronchoscopic
Bronchoscopic Surgery
Bronchoscopic Surgical Procedures
Bronchoscopy

Endoscopic examination, therapy or surgery of the bronchi.


A nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.


Genetic Therapy, Somatic
Somatic Gene Therapy
Therapy, Somatic Gene
Gene Therapy
Genetic Therapy
Genetic Therapy, Gametic
Therapy, DNA
Gene Therapy, Somatic
DNA Therapy
Therapy, Gene

The processes by which highly specific gene sequences in a host cell are targeted and regulated for the purpose of reversing and or curing a disease.


Taurochenodeoxycholate
Chenodeoxycholyltaurine
Taurine Chenodeoxycholate
Taurochenodeoxycholic Acid

A bile salt formed in the liver by conjugation of chenodeoxycholate with taurine, usually as the sodium salt. It acts as detergent to solubilize fats in the small intestine and is itself absorbed. It is used as a cholagogue and choleretic.


Cochlear Nerve Disorders
Vestibular Nerve Disorders
Vestibulocochlear Nerve Diseases
Cochlear Nerve Diseases
Acoustic Nerve Diseases
Cranial Nerve VIII Diseases
Eighth Cranial Nerve Diseases
Acoustic Nerve Disorders
Cranial Nerve VIII Disorders
Cochlear Neuritis
Vestibular Nerve Diseases

Pathological processes of the VESTIBULOCOCHLEAR NERVE, including the branches of COCHLEAR NERVE and VESTIBULAR NERVE. Common examples are VESTIBULAR NEURITIS, cochlear neuritis, and ACOUSTIC NEUROMA. Clinical signs are varying degree of HEARING LOSS; VERTIGO; and TINNITUS.


Unmarried Fathers
Legitimacy
Illegitimacy
Premarital Pregnancy
Unmarried Mothers
Pregnancy, Premarital

The state of birth outside of wedlock. It may refer to the offspring or the parents.


Total Hemispherectomy
Hemispherectomy
Functional Hemispherectomy
Partial Hemispherectomy

Removal of the entire cortex, sparing the BASAL GANGLIA.


Turkeypox virus
Turkey Pox Virus
Pigeon Pox Virus
Pigeonpox virus
Poxvirus avium
Bird Pox Virus
Avipoxvirus

A genus of the family POXVIRIDAE, subfamily CHORDOPOXVIRINAE, comprising bird poxviruses. The type species is FOWLPOX VIRUS. Transmission is mechanical by ARTHROPODS.


Cancer of the Fallopian Tube
Fallopian Tube Neoplasms
Fallopian Tube Cancer

Benign or malignant neoplasms of the FALLOPIAN TUBES. They are uncommon. If they develop, they may be located in the wall or within the lumen as a growth attached to the wall by a stalk.


Receptors, Corticosteroid
Corticosteroid Receptors
Steroid Receptors
Receptors, Steroids
Corticosteroid Receptor
Steroid Receptor
Receptors, Steroid

Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes.


Peracetic Acid, Sodium Salt
Peroxyethanoic Acid
Peroxyacetic Acid
Desoxone-1
Dialax
Zinc Peracetate
Acetyl Hydroperoxide
Sodium Peracetate
Peracetic Acid

A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.


Neoplasms, Anus
Neoplasms, Anal
Anus Neoplasms
Cancer of the Anus
Cancer of Anus
Anal Cancer
Anal Neoplasms


Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 2

UBIQUITIN-like modifier proteins that function in CYTOPLASM to VACUOLE transport (Cvt), vesicle transport within the GOLGI APPARATUS, and AUTOPHAGOSOME biogenesis. They are also required for selective autophagic degradation of the nucleus (nucleophagy) and MITOPHAGY.


A plant genus of the family ARALIACEAE. Members contain hederin (olean-12-ene) type TRITERPENES.


Leishmania brasiliensis peruviana
Leishmania brasiliensis
Leishmania viannia brasiliensis
Leishmania braziliensis peruviana
Leishmania viannia braziliensis
Leishmania brasiliensis brasiliensis
Leishmania (Viannia) braziliensis
Leishmania braziliensis
Leishmania (Viannia) brasiliensis
Leishmania braziliensis braziliensis

A parasitic hemoflagellate of the subgenus Leishmania viannia that infects man and animals. It causes cutaneous (LEISHMANIASIS, CUTANEOUS), diffuse cutaneous (LEISHMANIASIS, DIFFUSE CUTANEOUS), and mucocutaneous leishmaniasis (LEISHMANIASIS, MUCOCUTANEOUS) depending on the subspecies of this organism. The sandfly, Lutzomyia, is the vector. The Leishmania braziliensis complex includes the subspecies braziliensis and peruviana. Uta, a form of cutaneous leishmaniasis in the New World, is caused by the subspecies peruviana.


Brill Disease
Louse-Borne Typhus
Jail Fever
Epidemic Typhus
Brill-Zinsser Disease
Rickettsia prowazekii Infection
Typhus, Epidemic Louse-Borne
Typhus
Brill's Disease

The classic form of typhus, caused by RICKETTSIA PROWAZEKII, which is transmitted from man to man by the louse Pediculus humanus corporis. This disease is characterized by the sudden onset of intense headache, malaise, and generalized myalgia followed by the formation of a macular skin eruption and vascular and neurologic disturbances.


Sleep Disorders, Intrinsic
Intrinsic Sleep Disorders
Sleep State Misperception
Hypersomnia, Post-Traumatic
Hypersomnia, Posttraumatic

Dyssomnias (i.e., insomnias or hypersomnias) associated with dysfunction of internal sleep mechanisms or secondary to a sleep-related medical disorder (e.g., sleep apnea, post-traumatic sleep disorders, etc.). (From Thorpy, Sleep Disorders Medicine, 1994, p187)


Glycoprotein Complex IIb-IIIa, Deficiency Of

Platelet Glycoprotein IIb-IIIa Deficiency

Platelet Fibrinogen Receptor, Deficiency of

A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).


Lung Inflammation
Pneumonia, Lobar
Experimental Lung Inflammation
Pneumonitis
Pneumonia
Pulmonary Inflammation
Lobar Pneumonia

Inflammation of any part, segment or lobe, of the lung parenchyma.


Protein Kinase C beta I
Protein Kinase C beta II
Protein Kinase C beta
Protein Kinase C beta2
PKCB1
PKC-beta II
PKC beta 2
Protein Kinase C-beta (II)
PKCBII
PKC beta 1
PKC(beta)
Protein Kinase C beta1
PKCbeta2
Protein Kinase C-beta(II)

PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation.


Midline Nuclei of Thalamus
Reuniens Nucleus
Rhomboidal Nucleus
Subfascular Nucleus
Nucleus Reuniens
Periventricular Nuclei of Thalamus
Subfascular Thalamic Nucleus
Midline Nuclear Group
Nucleus Reuniens Thalami
Midline Thalamic Nuclei
Reuniens Thalamic Nucleus
Paratenial Nucleus
Parataenial Nucleus
Paraventricular Thalamic Nucleus
Paraventricular Nucleus of Thalamus
Rhomboid Nucleus
Paratenial Thalamic Nucleus
Rhomboid Thalamic Nucleus

Small, nonspecific nerve cells scattered in the periventricular GRAY MATTER, separating the medial part of the thalamus from the EPENDYMA of the THIRD VENTRICLE. The group includes the paraventricular nucleus, paratenial nucleus, reuniens nucleus, rhomboidal nucleus, and subfascular nucleus.


Organic Mental Disorders, Substance-Induced


Pustulosis, Exanthematous, Acute Generalized

Acute Generalized Exanthematous Pustulosis

Acute Localized Exanthematous Pustulosis

Pustulosis, Exanthematous, Acute Localized

Acute Generalised Exanthematous Pustulosis

Rare skin eruption characterized by acute formation of pustules filled with NEUTROPHILS, fever, and peripheral blood LEUKOCYTOSIS. Most cases are associated with the use of antibiotics (e.g., BETA-LACTAMS).


Cerastium
Brachystemma
Chickweed, Mouse-ear
Rupturewort
Drymaria
Caryophyllaceae
Herniaria
Spergularia


Advisory Services
Services, Advisory
Consultants

Individuals referred to for expert or professional advice or services.


Thrombostat
gamma-Thrombin
beta,gamma-Thrombin
beta-Thrombin
Thrombin-JMI
Thrombase
Thrombinar
alpha-Thrombin
Thrombin
Thrombin JMI

An enzyme formed from PROTHROMBIN that converts FIBRINOGEN to FIBRIN.


Sulbactam
Combactam
Bétamaze
CP-45899
Penicillanic Acid Sulfone
Sulbactam Sodium

A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.


Deficiency Disease, Hexosaminidase A and B

Hexosaminidase A and B Deficiency Disease

An autosomal recessive neurodegenerative disorder characterized by an accumulation of G(M2) GANGLIOSIDE in neurons and other tissues. It is caused by mutation in the common beta subunit of HEXOSAMINIDASE A and HEXOSAMINIDASE B. Thus this disease is also known as the O variant since both hexosaminidase A and B are missing. Clinically, it is indistinguishable from TAY-SACHS DISEASE.


Oxidoreductases Acting on Sulfur Group Donors

Oxidoreductases with specificity for oxidation or reduction of SULFUR COMPOUNDS.


Naproxen
Naprosin
Naprosyn
Aleve
Naproxen Sodium
Methoxypropiocin
Synflex
Proxen
Anaprox
Sodium Naproxenate

An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.


Administration
Techniques, Administrative
Administration and Organization
Organization and Administration
Coordination, Administrative
Administrative Technics
Logistics
Supervision
Technics, Administrative
Administrative Techniques

The planning and managing of programs, services, and resources.


Port-A-Cath
Vascular Access Devices
Vascular Access Ports
Venous Reservoirs
Intra-Arterial Lines
Arterial Lines
Port Catheters
Vascular Catheters

Devices to be inserted into veins or arteries for the purpose of carrying fluids into or from a peripheral or central vascular location. They may include component parts such as catheters, ports, reservoirs, and valves. They may be left in place temporarily for therapeutic or diagnostic purposes.


Echinostoma ilocanum
Euparyphium ilocanum
Echinostoma
Fascioletta ilocanum

A genus of intestinal flukes of the family Echinostomatidae which consists of many species. They occur in man and other vertebrates. The intermediate hosts are frequently mollusks.


Neocallimasticales Neocallimastigales Orpinomyces Sphaeromonas Anaeromyces Caecomyces Cyllamyces

An order of fungi in the phylum NEOCALLIMASTIGOMYCOTA comprising anaerobic chytrids that inhabit the RUMEN; and CECUM of herbivorous animals. Genera (all in the lone family Neocallimastigaceae) include NEOCALLIMASTIX, Orpinomyces, PIROMYCES, Anaeromyces, Cyllamyces, and Caecomyces.


raf Kinases
raf Proto-Oncogene Proteins
raf MAP Kinase Kinase Kinases
raf Serine-Theonine Protein Kinases
Proto-Oncogene Proteins raf
MIL-RAF Proteins
mil-raf Protein Kinases

A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION.


Cost Benefit Analysis
Costs and Benefits
Cost-Effectiveness Analysis
Benefits and Costs
Cost Benefit
Cost Effectiveness
Economic Evaluation
Cost-Benefit Data
Cost-Benefit Analysis
Marginal Analysis
Cost-Utility Analysis

A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.


Phikmvvirus
T7-like viruses
Podoviridae
Phages, T7-like
T7-like Phages

Genus in the family PODOVIRIDAE. The type species is BACTERIOPHAGE T7.


Type II Fish Antifreeze Proteins
Fish Type II AFP
Type II Antifreeze Proteins
Antifreeze Proteins, Type II
Fish Antifreeze Proteins, Type II

A subclass of ANTIFREEZE PROTEINS that have a cystine-rich globular structure of approximately 14 kD.


Joint Dislocations
Joint Subluxations
Inferior Dislocation
Luxatio Erecta

Partial or incomplete displacement of an articulation.


Nursing, Military and Naval
Nursing, Military
Military Nursing
Military and Naval Nursing

The practice of nursing in military environments.


English Chamomile
Camomile, Roman
Anthemis nobilis
Chamaemelum
Chamomile, Roman
Chamaemelum nobile

A plant genus of the family ASTERACEAE that is used in folk medicine as CHAMOMILE. Other plants with similar common names include MATRICARIA; TRIPLEUROSPERMUM and ANTHEMIS.


Medical Specialty
Specialty, Medical
Specialities, Medical
Medical Specialties
Medical Specialities
Specialties, Medical
Medicine

Various branches of medical practice limited to specialized areas.


A nucleoside in which THYMINE is linked to DEOXYRIBOSE.


An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION.


Dextran
Promit
Dextran T 70
Dextran B512
Dextran 80
Rheopolyglucin
Dextran M 70
Dextrans
Dextran 40000
Dextran T-500
Dextran B-1355-S
Dextran Derivatives
Dextran B1355
Dextran 40
Macrodex
Rheomacrodex
Rheoisodex
Dextran B-1355
Hyskon
Rondex
Dextran 75
Hemodex
Dextran T-40
Infukoll
Polyglucin
Saviosol
Dextran 70
Rheodextran

A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.


A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.


Isobutylamides, Polyunsaturated
Alkamides, Polyunsaturated
Polyunsaturated Alkamides
Polyunsaturated Alkylamides
Alkylamides, Polyunsaturated
Polyunsaturated Isobutylamides

Amides composed of unsaturated aliphatic FATTY ACIDS linked with AMINES by an amide bond. They are most prominent in ASTERACEAE; PIPERACEAE; and RUTACEAE; and also found in ARISTOLOCHIACEAE; BRASSICACEAE; CONVOLVULACEAE; EUPHORBIACEAE; MENISPERMACEAE; POACEAE; and SOLANACEAE. They are recognized by their pungent taste and for causing numbing and salivation.


Haemophilia
Factor VIII Deficiency, Congenital
Factor VIII Deficiency
Deficiency, Factor VIII
Autosomal Hemophilia A
Hemophilia
Hemophilia A
Classic Hemophilia
Hemophilia A, Congenital
Factor 8 Deficiency, Congenital
Hemophilia, Classic

The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.


Hamamelis
Hamamelis virginiana
Witch Hazel

A plant genus of the family Hamamelidaceae, order Hamamelidales. It is known for the astringent (ASTRINGENTS) extract of leaves and bark used in over the counter preparations. This should not be confused with the similar named Hamelia genus (RUBIACEAE).


fms Genes
Genes, fms
c-fms Proto-Oncogenes
v-fms Genes
c-fms Genes
v-fms Oncogenes

Family of genes originally isolated from the Susan McDonough strain of feline sarcoma virus (SARCOMA VIRUSES, FELINE). The proto-oncogene fms (c-fms) codes for the MCSF receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR). The oncogene fms (v-fms) codes for ONCOGENE PROTEIN GP140(V-FMS) which is a mutated form of the MCSF. The human c-fms gene is located between 5q33.2 and 5q33.3.


Rattus
Rats, Norway
Rattus norvegicus
Rats, Laboratory
Rats


Ulva
Sea Lettuce
Sea Lettuces
Ulva arasakii

A genus of GREEN ALGAE in the family Ulvaceae. Commonly know as sea lettuces, they grow attached to rocks and KELP in marine and estuarine waters.


Biological Processes
Biological Phenomena
Biologic Phenomena
Phenomena, Biological
Biological Phenomenon
Biological Process

Biological processes, properties, and characteristics of the whole organism in human, animal, microorganisms, and plants, and of the biosphere.


Diagnosis, Antenatal
Intrauterine Diagnosis
Prenatal Screening
Antenatal Screening
Diagnosis, Prenatal
Diagnosis, Intrauterine
Prenatal Diagnosis
Antenatal Diagnosis

Performing various procedures and tests on the EMBRYO; FETUS; or mother for the detection of diseases.


Aspartic Acid, Magnesium-Potassium (2:1:2) Salt

Aspartic Acid, Magnesium (1:1) Salt, Hydrochloride, Trihydrate

One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.


Memory, Remote
Memory, Long-Term
Remote Memory
Memory, Longterm

Information learned before age 12 and less subject to disruption than intermediate memory.


Mendelson's Syndrome
Acid Aspiration Syndrome
Gastric Acid Aspiration Syndrome
Pneumonia, Aspiration
Aspiration Pneumonia
Mendelson Syndrome

A type of lung inflammation resulting from the aspiration of food, liquid, or gastric contents into the upper RESPIRATORY TRACT.


Poisoning, Illuminating Gas
Illuminating Gas Poisoning
Poisoning, Carbon Monoxide
Carbon Monoxide Poisoning

Toxic asphyxiation due to the displacement of oxygen from oxyhemoglobin by carbon monoxide.


Prescriptions, Nondrug
Prescriptions
Prescriptions, Non-Drug

Directions written for the obtaining and use of PHARMACEUTICAL PREPARATIONS; MEDICAL DEVICES; corrective LENSES; and a variety of other medical remedies.


Dental Practice Management Services
Practice Management, Dental
Management, Dental Practice
Practice Management Services, Dental
Dental Practice Management

The organization and operation of the business aspects of a dental practice.


Pick's Disease of Heart
Constrictive Pericarditis
Pericarditis, Constrictive
Pick Disease of Heart

Inflammation of the PERICARDIUM that is characterized by the fibrous scarring and adhesion of both serous layers, the VISCERAL PERICARDIUM and the PARIETAL PERICARDIUM leading to the loss of pericardial cavity. The thickened pericardium severely restricts cardiac filling. Clinical signs include FATIGUE, muscle wasting, and WEIGHT LOSS.


Type IV Renal Tubular Acidosis
Hyporeninemic Hypoaldosteronism
Renal Tubular Acidosis, Type IV
Acidosis, Renal Tubular Type IV
Hypoaldosteronism
Hypoaldosteronism, Hyporeninemic

A selective aldosterone deficiency resulting from diminished RENIN-generated ANGIOTENSIN II, a key stimulus to aldosterone secretion. Previously, it was called type IV renal tubular acidosis.


IL-5902
Antibiotic 799
Spiramycin
Rovamycin
Spiramycin Adipate
Spiramycine
NSC-55926
NSC-64393
Rovamycine
Selectomycin

A macrolide antibiotic produced by Streptomyces ambofaciens. The drug is effective against gram-positive aerobic pathogens, N. gonorrhoeae, and staphylococci. It is used to treat infections caused by bacteria and Toxoplasma gondii.


Mosquito Bed Net
Mosquito Netting
Mosquito Nets
Mosquito Bednet
Portable Mosquito Net

Free-standing or supported lightweight meshwork fabric made of cotton, silk, polyester or other material, having openings too small to allow entry of mosquitoes or other insects, thereby protecting against INSECT BITES; INSECT STINGS, and insect-borne diseases.


Lipopeptides
Anionic Lipopeptide
Anionic Lipopeptides
Cationic Lipopeptide
Cationic Lipopeptides

Lipopeptides with an cationic peptide scaffold.


A plant family of the order Nepenthales, subclass Dilleniidae, class Magnoliopsida, notable for leaves with sticky gland-tipped hairs that entrap insects.


A species of BETARETROVIRUS isolated from mammary carcinoma in rhesus monkeys. It appears to have evolved from a recombination between a murine B oncovirus and a primate C oncovirus related to the baboon endogenous virus. Several serologically distinct strains exist. MPMV induces SIMIAN AIDS.


Horehound, Woolly
Marrubium
Horehound
Marrubium vulgare
Horehound, Common

A plant genus of the LAMIACEAE family that contains marrubiin (a labdane diterpene). It is known as a traditional medicinal for sore throat.


Sialic Acid Storage Disease, Finnish Type

Infantile Sialic Acid Storage Disorder (ISSD)

Sialic Acid Storage Disease, Infantile Form

Autosomal recessive neurodegenerative disorders caused by lysosomal membrane transport defects that result in accumulation of free sialic acid (N-ACETYLNEURAMINIC ACID) within the lysosomes. The two main clinical phenotypes, which are allelic variants of the SLC17A5 gene, are ISSD, a severe infantile form, or Salla disease, a slowly progressive adult form, named for the geographic area in Finland where the kindred first studied resided.


Cycloplegics
Mydriatic Effect
Mydriatics
Mydriatic Effects

Agents that dilate the pupil. They may be either sympathomimetics or parasympatholytics.


UV Light
Ultraviolet Radiation
Black Light, Ultraviolet
Ultra-Violet Rays
Actinic Rays
Ultraviolet Light
UV Radiation
Ultraviolet Rays

That portion of the electromagnetic spectrum immediately below the visible range and extending into the x-ray frequencies. The longer wavelengths (near-UV or biotic or vital rays) are necessary for the endogenous synthesis of vitamin D and are also called antirachitic rays; the shorter, ionizing wavelengths (far-UV or abiotic or extravital rays) are viricidal, bactericidal, mutagenic, and carcinogenic and are used as disinfectants.


Chemexfoliation
Chemical Face Peeling
Face Peeling, Chemical

Application of a cauterant to the skin for the purpose of causing a superficial destruction of the epidermis and upper layers of the dermis. After healing, the treated area has new epithelium.


Corticotropin-Like Intermediate Lobe Peptide

A peptide derived from the cleavage of ADRENOCORTICOTROPIC HORMONE, found primarily in the INTERMEDIATE LOBE OF PITUITARY but also in the ARCUATE NUCLEUS of basal HYPOTHALAMUS. Its sequence is identical to the C-terminal 22-amino acids of ACTH or ACTH 18-39.


Injuries, Cranial Nerve VII
Marginal Mandibular Nerve Injuries
Injury, Facial Nerve
Facial Nerve Trauma
Facial Nerve Injuries
Facial Nerve Avulsion
Marginal Mandibular Nerve Injury
Injuries, Seventh Cranial Nerve
Seventh Cranial Nerve Injuries
Nerve Injury, Facial
Facial Neuropathy, Traumatic
Cranial Nerve VII Injuries

Traumatic injuries to the facial nerve. This may result in FACIAL PARALYSIS, decreased lacrimation and salivation, and loss of taste sensation in the anterior tongue. The nerve may regenerate and reform its original pattern of innervation, or regenerate aberrantly, resulting in inappropriate lacrimation in response to gustatory stimuli (e.g., "crocodile tears") and other syndromes.


Phylogenetic DNA Barcode
DNA Barcoding, Taxonomic
Taxonomic DNA Barcoding
Taxonomic DNA Barcodes
Phylogenetic DNA Barcoding
DNA Barcode, Taxonomic
Taxonomic DNA Barcode

A chosen region of DNA, about 650 basepair long, from a precise location in a well characterized, constitutively- expressed gene that is known to vary more between species than between individuals of a species. For example, a precise portion of the mitochondrial gene for CYCLOOXYGENASE 1 has been used as a standard DNA barcode for animals.


Nalidixate Sodium
Nevigramon
Sodium Nalidixic Acid, Monohydrate
Nalidixin
Nalidixic Acid
Nalidixate Sodium Anhydrous
Sodium Nalidixic Acid, Anhydrous

A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.


Scanning Transmission Electron Microscopy Tomography

A tomographic technique for obtaining 3-dimensional images with transmission electron microscopy.


Fluticasone Propionate-Salmeterol Xinafoate Drug Combination

Fluticasone Propionate - Salmeterol Xinafoate

Fluticasone Propionate-Salmeterol Drug Combination

Fluticasone Propionate, Salmeterol Xinafoate Drug Combination

Fluticasone Propionate-Salmeterol Xinafoate Combination

Fluticasone Propionate - Salmeterol Combination

A metered dose inhaler formulation of fluticasone-salmeterol drug combination.


Pressure Pneumothorax
Spontaneous Pneumothorax
Tension Pneumothorax
Pneumothorax
Primary Spontaneous Pneumothorax

An accumulation of air or gas in the PLEURAL CAVITY, which may occur spontaneously or as a result of trauma or a pathological process. The gas may also be introduced deliberately during PNEUMOTHORAX, ARTIFICIAL.


Deutan Defect
Color Blindness, Blue
Color Blindness, Acquired
Achromatopsia
Color Blindness, Red
Color Blindness, Green
Monochromatopsia
Color Blindness
Color Vision Defects
Color Vision Deficiency
Protan Defect
Color Blindness, Inherited
Tritan Defect
Color Blindness, Red-Green

Severely deficient color perception, typically with monochromacy and reduced visual acuity. The atypical form can include normal visual acuity with pseudomonochromacy.


Q beta Phage
Coliphage Q beta
Allolevivirus
Phage Q beta
Bacteriophage Q beta
Enterobacteria phage Q beta

A bacteriophage genus of the family LEVIVIRIDAE, whose viruses contain the longer version of the genome and have no separate cell lysis gene.


PPM1 Magnesium-Dependent Protein Phosphatases

Magnesium-Dependent Protein Phosphatase 2C beta

Protein Phosphatase 1D Magnesium-Dependent, delta isoform

One of four major classes of mammalian serine/threonine specific protein phosphatases. Protein phosphatase 2C is a monomeric enzyme about 42 kDa in size. It shows broad substrate specificity dependent on divalent cations (mainly manganese and magnesium). Three isozymes are known in mammals: PP2C -alpha, -beta and -gamma. In yeast, there are four PP2C homologues: phosphatase PTC1 that have weak tyrosine phosphatase activity, phosphatase PTC2, phosphatase PTC3, and PTC4. Isozymes of PP2C also occur in Arabidopsis thaliana where the kinase-associated protein phosphatase (KAPP) containing a C-terminal PP2C domain, dephosphorylates Ser/Thr receptor-like kinase RLK5.


Arthroplasty, Hip Replacement
Arthroplasty, Replacement, Hip
Replacement Arthroplasty, Hip
Hip Prosthesis Implantation
Replacement, Total Hip
Total Hip Replacement
Hip Replacement, Total
Arthroplasties, Replacement, Hip
Hip Replacement Arthroplasties
Hip Replacement Arthroplasty
Replacement Arthroplasties, Hip
Arthroplasties, Hip Replacement


Receptor, Endothelin B, Type 2
Endothelin B-2 Receptors
Endothelin B Receptors
Endothelin B-2 Receptor
Receptor, Endothelin B

A subtype of endothelin receptor found predominantly in the KIDNEY. It may play a role in reducing systemic ENDOTHELIN levels.


Rhonchi
Lung Sounds
Rales
Respiratory Sounds
Breathing Sounds
Stridor
Wheezing
Pleural Rub
Crackles

Noises, normal and abnormal, heard on auscultation over any part of the RESPIRATORY TRACT.


A synthetic fluorinated steroid that is used as a progestational hormone.


MK-486
Lodosin
Carbidopa, (S)-Isomer
Methyldopahydrazine
Carbidopa, (R)-Isomer
MK-485
Lodosyn
Carbidopa

An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself.


Bee Colony Collapse
Colony Collapse Disorder
Colony Collapse

A disorder of unknown cause affecting honeybees, whereby a colony rapidly loses its adult bee population. ISRAELI ACUTE PARALYSIS VIRUS OF BEES may have a role in the disorder.


Bacterial Load
Count, Bacterial
Counts, Bacterial
Bacterial Count
Bacterial Counts

Measurable quantity of bacteria in an object, organism, or organism compartment.


Congenital Diaphragmatic Hernias
Congenital Diaphragmatic Defect
Morgagni's Hernias
Agenesis of Hemidiaphragm
Hernias, Diaphragmatic, Congenital
Unilateral Agenesis of Diaphragm
Morgagni Hernias
Bochdalek Hernias

Protrusion of abdominal structures into the THORAX as a result of embryologic defects in the DIAPHRAGM often present in the neonatal period. It can be isolated, syndromic, nonsyndromic or be a part of chromosome abnormality. Associated pulmonary hypoplasia and PULMONARY HYPERTENSION can further complicate stabilization and surgical intervention.


Waterbirth
Water Birth
Natural Childbirth
Lamaze Technique

Labor and delivery without medical intervention, usually involving RELAXATION THERAPY.


Nightshade
Nightshade, Laciniate
Poroporo
Horsenettle
Nettle, Horse
Nightshade, Bitter
Solanum laciniatum
Trompillo
Solanum dulcamara
Solanum

A plant genus of the family SOLANACEAE. Members contain SOLANACEOUS ALKALOIDS. Some species in this genus are called deadly nightshade which is also a common name for ATROPA BELLADONNA.


Fractures, Bone
Spiral Fractures
Broken Bones
Bone Fractures
Torsion Fractures


Vagal-immune Interactions
Neuro-immune Interactions
Vagal Anti-inflammatory Pathway
Neuroimmunomodulation
Neuroimmune Processes
Neuro-immunomodulation
Neuroimmune Mechanisms
Neuro-immune Axis
Neuro-immune Communication
Neuroimmune Interactions
Neuroimmune Axis
Neuroimmune Process
Neuroimmune Communication
Cholinergic Anti-inflammatory Pathway

Functional circuit between the VAGUS NERVE and innate inflammatory response (see INNATE IMMUNITY).


A plant genus of the family ARISTOLOCHIACEAE. Species of this genus have been used in traditional medicine but they contain aristolochic acid which is associated with nephropathy. These are sometimes called 'snakeroot' but that name is also used with a number of other plants such as POLYGALA; SANICULA; ASARUM; ARISTOLOCHIA; AGERATINA; and others.


TRAP (Thyroid Hormone Associated Protein) Complex

Thyroid Hormone-Associated Protein Complex

A large protein complex which acts as a signaling adaptor protein that allows communication between the various regulatory and functional components of GENETIC TRANSCRIPTION including DNA POLYMERASE II; GENERAL TRANSCRIPTION FACTORS; and TRANSCRIPTION FACTORS that are bound to upstream ENHANCER ELEMENTS. The mediator complex was originally studied in YEAST where at least 21 subunits were identified. Many of the yeast subunits are homologs to proteins in higher organisms that are found associated with specific nuclear receptors such as THYROID HORMONE RECEPTORS and VITAMIN D RECEPTORS.


NADPH Thyroid Oxidase 2
DUOX1
Thyroid Oxidase 2
Dual Oxidase 2
Duox Proteins
Dual Oxidases
DUOX2
Dual Oxidase 1

NADPH oxidases that contain two additional EF HAND MOTIFS and an N-terminal PEROXIDASE domain. They are expressed by THYROCYTES and EPITHELIAL CELLS of the kidney, liver, trachea, lung, and glandular tissues such as the testis, pancreas, and prostate. They are critical for the activity of THYROID PEROXIDASE and play a role in the production of thyroid hormones; they may also have antimicrobial activity through the generation of REACTIVE OXYGEN SPECIES.


A fluoroquinolone that acts as an inhibitor of DNA TOPOISOMERASE II and is used as a broad-spectrum antibacterial agent.


(5beta)-3,7,12-Trioxocholan-24-oic Acid
Decholin
Dehydrocholic Acid, Sodium Salt
Dehydrocholic Acid
Dehydrocholic Acid, Lithium Salt
Chologon
Dehydrocholate
Ketocholanic Acid
Dehydrocholic Acid, Magnesium Salt
Triketocholanic Acid
Cholan-HMB
Dehydrocholic Acid, Potassium Salt
Sodium Dehydrocholate
Trioxocholate
Atrocholin

A semisynthetic bile acid made from cholic acid. It is used as a cholagogue, hydrocholeretic, diuretic, and as a diagnostic aid.


Infection, Delta
Delta Hepatitis
Black Fever, Amazon
Superinfection, Delta
Amazon Black Fever
Hepatitis D
Delta Infection
Delta Superinfection
Hepatitis, Delta
Labrea Disease

INFLAMMATION of the LIVER in humans caused by HEPATITIS DELTA VIRUS, a defective RNA virus that can only infect HEPATITIS B patients. For its viral coating, hepatitis delta virus requires the HEPATITIS B SURFACE ANTIGENS produced by these patients. Hepatitis D can occur either concomitantly with (coinfection) or subsequent to (superinfection) hepatitis B infection. Similar to hepatitis B, it is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.


Purinergic Effect
Purinergic Effects
Purinergic Agents

Compounds that act on PURINERGIC RECEPTORS or influence the synthesis, storage, uptake, metabolism, or release of purinergic transmitters.


Niosomes
Ultradeformable Liposomes
Liposomes, Ultra-deformable
Transferosomes
Liposomes

Liposomes prepared to be much more deformable and so more capable of SKIN penetration.


Nuclear Receptor Subfamily 2, Group A, Member 1

Hepatocyte Nuclear Factor-Forkhead Homolog 4

Nuclear Receptor Subfamily 2 Group A, Member 2

A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES involved in the synthesis of BLOOD COAGULATION FACTORS; and in GLUCOSE; CHOLESTEROL; and FATTY ACIDS metabolism.


A family of calcium-independent cell adhesion molecules of the immunoglobulin superfamily. They are expressed by most cell types and mediate both homotypic and heterotypic cell-cell adhesion. Nectins function in a variety of morphogenetic and developmental processes that include organogenesis of the eye, ear, tooth, and cerebral cortex; they also play roles in viral infection and cell proliferation.


Retinal Muller Cells
Muller Cells
Radial Glial Cells
Ependymoglial Cells
Tanycytes

The principal macroglial cells of the RETINA with polygonal cell body shape and having processes that span the full thickness of the retina and contact VITREOUS BODY and the sub-retinal space.


Sitting Position
Seated Position
Sitting

Putting the weight of the body,  against the ground or a horizontal object such as a chair seat.


Methoxyflurane Methofluranum Pentrane Penthrane Anecotan

An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with NITROUS OXIDE to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)


Intravesical Drug Administration
Instillation, Bladder
Intravesical Instillation
Intravesical Injection
Drug Administration, Bladder
Intravesical Administration
Administration, Intravesical Drug
Bladder Drug Administration
Administration, Intravesical
Injections, Intravesical

The instillation or other administration of drugs into the bladder, usually to treat local disease, including neoplasms.


Compression Devices, Intermittent Pneumatic

Intermittent Pneumatic Compression Devices

Instruments that generate intermittent forces, uniformed or graduated, to facilitate the emptying of VEINS. These devices are used to reduce limb EDEMA and prevent venous THROMBOEMBOLISM, such as deep vein thrombosis in the legs.


Bisbenzylisoquinolines Benzylisoquinolines Bis-Benzylisoquinolines Benzyl-Isoquinolines Bis-Benzyl-Isoquinolines

ISOQUINOLINES with a benzyl substituent.


Epilepsy, Major
Epilepsy, Tonic-Clonic, Symptomatic
Tonic-Clonic Convulsion Syndrome
Major Motor Seizure Disorder
Symptomatic Tonic-Clonic Epilepsy
Tonic-Clonic Convulsion Disorder
Epilepsy, Grand Mal
Tonic Clonic Convulsions
Convulsions, Grand Mal
Familial Tonic-Clonic Epilepsy
Tonic-Clonic Seizure Disorder
Epilepsy, Tonic-Clonic
Tonic-Clonic Seizure Syndrome
Grand Mal Seizure Disorder
Epilepsy, Tonic-Clonic, Familial
Cryptogenic Tonic-Clonic Epilepsy
Seizure Disorder, Major Motor
Seizure Disorder, Grand Mal
Epilepsy, Tonic-Clonic, Cryptogenic
Seizure Disorder, Tonic Clonic

A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)


Ophthochlor Levomycetin Cloranfenicol Chloromycetin Chloramphenicol Detreomycin Chlornitromycin Chlorocid Amphenicol Amphenicols Syntomycin Kloramfenikol


Torafugu
Fugu
Takifugu rubripes
Fugu rubripes
Takifugu

A species commonly used for molecular biology research and a well known model organism for the vertebrate genome.


Pectins
Calcium Pectinate
Methoxylpectin
Methoxypectin
Pectinic Acid
Pectin
Methoxy Pectin
Zinc Pectinate

High molecular weight polysaccharides present in the cell walls of all plants. Pectins cement cell walls together. They are used as emulsifiers and stabilizers in the food industry. They have been tried for a variety of therapeutic uses including as antidiarrheals, where they are now generally considered ineffective, and in the treatment of hypercholesterolemia.


Cell Division Cycle 25B protein
M-Phase Inducer Phosphatase 1
Dual Specificity Phosphatase Cdc25B
Dual Specificity Phosphatase Cdc25A
cdc25 Phosphatases
cdc25B Phosphatase
cdc25C Phosphatase
Dual Specificity Phosphatase Cdc25C
cdc25 Phosphatase
M-Phase Inducer Phosphatase 3
M-Phase Inducer Phosphatase 2
cdc25A Phosphatase

A subclass of dual specificity phosphatases that play a role in the progression of the CELL CYCLE. They dephosphorylate and activate CYCLIN-DEPENDENT KINASES.