A form of ventricular pre-excitation characterized by a normal PR interval and a long QRS interval with an initial slow deflection (delta wave). In this syndrome, the atrial impulse travel to the ventricle via the MAHAIM FIBERS which connect ATRIOVENTRICULAR NODE directly to the right ventricle wall (NODOVENTRICULAR ACCESSORY PATHWAY) or to the RIGHT BUNDLE BRANCH OF HIS (nodofascicular accessory pathway).


A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic α2A and α2C receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER.


SNOMED Clinical Terms
SNOMED
SNOMED Reference Terminology
Systematized Nomenclature of Medicine
SNOMED RT
SNOMED CT

Combined content of reference terminology and READ codes.


LY 139481
Raloxifene
LY-139481
Keoxifene
Evista
LY-156758
Raloxifene HCl
Keoxifene Hydrochloride
LY 156758
Raloxifene Hydrochloride

A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.


Chamomile, Scentless
Tripleurospermum perforatum
Tripleurosperum perforatum
Tripleurospermum
Camomile, Scentless
Matricaria perforata
Mayweed, False

A plant genus of the family ASTERACEAE. It is easily confused with related plants with similar common names of Chamomile and Mayweed (MATRICARIA; CHAMAEMELUM; and ANTHEMIS).


Ibandronic Acid, Sodium Salt, Monohydrate

Aminobisphosphonate that is a potent inhibitor of BONE RESORPTION. It is used in the treatment of HYPERCALCEMIA associated with malignancy, for the prevention of fracture and bone complications in patients with breast cancer and bone metastases, and for the treatment and prevention of POSTMENOPAUSAL OSTEOPOROSIS.


Anthocyanidin Anthocyanins Leucoanthocyanidins Anthocyanin Anthocyanidins


Pulmonary Thromboembolisms
Thromboembolism, Pulmonary
Pulmonary Embolism
Embolisms, Pulmonary
Pulmonary Embolisms
Thromboembolisms, Pulmonary
Pulmonary Thromboembolism
Embolism, Pulmonary

Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.


Botulism
Botulism, Toxico-Infectious
Foodborne Botulism
Botulism, Infantile
Wound Botulism
Clostridium botulinum Infection
Infant Botulism
Toxico-Infectious Botulism

A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)


Economic Community, European
Common Market
European Common Market
EEC
European Economic Community
European Community
European Atomic Energy Community
European Coal and Steel Community
Community, European Economic
European Union
Euratom

The collective designation of three organizations with common membership: the European Economic Community (Common Market), the European Coal and Steel Community, and the European Atomic Energy Community (Euratom). It was known as the European Community until 1994. It is primarily an economic union with the principal objectives of free movement of goods, capital, and labor. Professional services, social, medical and paramedical, are subsumed under labor. The constituent countries are Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden, and the United Kingdom. (The World Almanac and Book of Facts 1997, p842)


Transversus Abdominis
Pyramidalis Muscle
Quadratus Abdominis
Abdominal Muscles
Cremaster Muscle
Transverse Abdominal

Muscles forming the ABDOMINAL WALL including RECTUS ABDOMINIS; ABDOMINAL OBLIQUE MUSCLES, transversus abdominis, pyramidalis muscles and quadratus abdominis.


Plaice
Pleuronectes
Halibut
Pseudopleuronectes
Pleuronectes platessa
Flounder
Platichthys

Genus of Pleuronectidae comprising European flounder.


alpha 1-globin
alpha-Globin
alpha-2 Globin
alpha-Globins
alpha-1 Globin

Members of the alpha-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 16. They include zeta-globin and alpha-globin. There are also pseudogenes of zeta (theta-zeta) and alpha (theta-alpha) in the cluster. Adult HEMOGLOBIN is comprised of 2 alpha-globin chains and 2 beta-globin chains.


Accessory Nucleus of the Ventral Horn
Area Lateralis Hypothalami
Lateral Hypothalamic Nucleus
Area Hypothalamica Lateralis
Hypothalamic Area, Lateral
Lateral Tuberal Nuclei
Lateral Tuberal Nucleus
Lateral Hypothalamic Area
Lateral Hypothalamus
Tuberomammillary Nucleus

Area in the hypothalamus bounded medially by the mammillothalamic tract and the anterior column of the FORNIX (BRAIN). The medial edge of the INTERNAL CAPSULE and the subthalamic region form its lateral boundary. It contains the lateral hypothalamic nucleus, tuberomammillary nucleus, lateral tuberal nuclei, and fibers of the MEDIAL FOREBRAIN BUNDLE.


National Health Insurance
National Health Insurance, Non U.S.
Services, National Health
Health Services, National
National Health Services
National Health Insurance, Non-U.S.
National Health Programs

Components of a national health care system which administer specific services, e.g., national health insurance.


CASP8 and FADD-Like Apoptosis Regulating Protein

An APOPTOSIS-regulating protein that is structurally related to CASPASE 8 and competes with CASPASE 8 for binding to FAS ASSOCIATED DEATH DOMAIN PROTEIN. Two forms of CASP8 and FADD-like apoptosis regulating protein exist, a long form containing a caspase-like enzymatically inactive domain and a short form which lacks the caspase-like domain.


Acetylprocainamide
N-Acetylprocainamide
Acecainide Monohydrochloride
Acecainide Hydrochloride
Acecainide

A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.


Autoimmune Disorders of the Nervous System

Autoimmune Diseases of the Nervous System

Disorders caused by cellular or humoral immune responses primarily directed towards nervous system autoantigens. The immune response may be directed towards specific tissue components (e.g., myelin) and may be limited to the central nervous system (e.g., MULTIPLE SCLEROSIS) or the peripheral nervous system (e.g., GUILLAIN-BARRE SYNDROME).


Polycystic Kidney, Type 1 Autosomal Dominant Disease

Polycystic Kidney, Type 2 Autosomal Dominant Disease

Polycystic Kidney Disease, Adult, Type II

Polycystic Kidney Disease, Autosomal Dominant

Type 1 ADPKD is linked to gene mutation at the PKD1 locus on the short arm of CHROMOSOME 16.


Winstrol Stanazolol Androstanazol Stanozolol Methylstanazol Stromba

A synthetic steroid that has anabolic and androgenic properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1194)


Inferior Anal Nerve
Pudendal Nerve
Dorsal Nerve of Clitoris
Dorsal Nerve of Penis
Inferior Hemorrhoidal Nerve
Perineal Nerve
Dorsal Penile Nerve
Dorsal Clitoris Nerve

A nerve which originates in the sacral spinal cord (S2 to S4) and innervates the PERINEUM, the external GENITALIA, the external ANAL SPHINCTER and the external urethral sphincter. It has three major branches: the perineal nerve, inferior anal nerves, and the dorsal nerve of penis or clitoris.


Anosognosia
Finger Agnosia
Agnosia for Temperature
Visual Disorientation Syndrome
Agnosia for Taste
Somatosensory Agnosia
Gustatory Agnosia
Position Agnosia
Visual Agnosia
Ideational Agnosia
Agnosia for Pain
Auditory Agnosia, Congenital
Body-Image Agnosia
Sensory Agnosia
Time Agnosia
Agnosia for Smell
Olfactory Agnosia
Tactile Agnosia
Visuospatial Agnosia
Topographical Agnosia
Visual Agnosia for Objects
Agnosia
Auditory Agnosia
Developmental Agnosia
Congenital Auditory Agnosia

A condition in which a person who suffers illness or disability seems unaware of or denies the existence of the illness or disability.


Protein Structural Homology
Protein Structural Homologs
3-Dimensional Homologs, Protein
3-D Homology, Protein
3-Dimensional Homology, Protein
Homologs, 3-D, Protein
Homologs, Sturctural, Protein
Homologs, 3-Dimensional, Protein
Structural Homologs, Protein
Structural Homology, Protein
3-D Homologs, Protein

The degree of 3-dimensional shape similarity between proteins. It can be an indication of distant AMINO ACID SEQUENCE HOMOLOGY and used for rational DRUG DESIGN.


Cystoid Macular Dystrophy
Macular Dystrophy, Dominant Cystoid
Macular Edema
Irvine-Gass Syndrome
Cystoid Macular Edema
Macular Edema, Cystoid
Central Retinal Edema, Cystoid
Cystoid Macular Edema, Postoperative

Fluid accumulation in the outer layer of the MACULA LUTEA at the center of the RETINA in a petaloid pattern where cystic spaces are formed and may lead to macular depressions or holes.


Thistle, Sow
Sonchus arvensis
Thistle, Field Milk
Sonchus

A plant genus of the family ASTERACEAE. Sesquiterpene lactone glucosides (SESQUITERPENES) have been found in it.


Hospital Renovations
Hospital Designs
Hospital Design and Construction
Hospital Construction and Design
Hospital Renovation
Hospital Construction
Hospital Design

The architecture, functional design, and construction of hospitals.


Herbalism
Herbal Medicine
La au Lapa au
Medicine, Herbal
La'au Lapa'au
Hawaiian Herbal Medicine
Laau Lapaau

The study of medicines derived from botanical sources.


Stem Cells
Colony-Forming Unit
Progenitor Cells
Colony-Forming Units
Mother Cells

Relatively undifferentiated cells that retain the ability to divide and proliferate throughout postnatal life to provide progenitor cells that can differentiate into specialized cells.


Glutamic Acid
Glutamic Acid, (D)-Isomer
D-Glutamate
L-Glutamic Acid
Potassium Glutamate
L-Glutamate
Glutamate
Aluminum L-Glutamate

A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.


Synaptobrevin
Vesicle-Associated Membrane Proteins
Synaptobrevins
R-SNARES
R-SNARE Proteins
Vesicle-Associated Membrane Protein

SNARE proteins where the central amino acid residue of the SNARE motif is an ARGININE. They are classified separately from the Q-SNARE PROTEINS where the central amino acid residue of the SNARE motif is a GLUTAMINE. This subfamily contains the vesicle associated membrane proteins (VAMPs) based on similarity to the prototype for the R-SNAREs, VAMP2 (synaptobrevin 2).


Fluocinonide
Lidex
Metosyn
Fluocinonide FAPG
Novoter
Topsyne
Fluocinolone Acetonide 21-Acetate
Topsym
Lidemol
Tiamol
Lyderm
Klariderm
Fluocinolide
Topsyn

A topical glucocorticoid used in the treatment of ECZEMA.


Alotec
Alupent
Metaprel
Astmopent
Metaproterenol Polistirex
Metaproterenol Sulfate
Orciprenaline Sulfate
Metaproterenol
Orciprenaline

A beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.


Cerebellar Neoplasms, Benign
Malignant Cerebellar Neoplasms
Cerebellar Neoplasms, Malignant
Primary Neoplasms, Cerebellum
Cerebellar Neoplasms, Primary
Neoplasms, Cerebellar, Primary
Neoplasms, Cerebellar
Cerebellar Neoplasms
Neoplasms, Cerebellar, Benign
Neoplasms, Cerebellar, Malignant
Cerebellar Tumors
Benign Cerebellar Neoplasms
Cerebellar Cancer

Primary or metastatic neoplasms of the CEREBELLUM. Tumors in this location frequently present with ATAXIA or signs of INTRACRANIAL HYPERTENSION due to obstruction of the fourth ventricle. Common primary cerebellar tumors include fibrillary ASTROCYTOMA and cerebellar HEMANGIOBLASTOMA. The cerebellum is a relatively common site for tumor metastases from the lung, breast, and other distant organs. (From Okazaki & Scheithauer, Atlas of Neuropathology, 1988, p86 and p141)


The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.


Praziquantel, (R)-Isomer
Cesol
Praziquantel
Cysticide
Praziquantel, (S)-Isomer
Biltricide
Cisticid
Traziquantel
Pyquiton
Drontsit
Droncit
EMBAY 8440
Praziquantel, (+-)-Isomer
Prasiquantel

An anthelmintic used in most schistosome and many cestode infestations.


Carney Myxoma-Endocrine Complex, Type II

LAMB - Lentigines, Atrial Myxoma, Mucocutaneous Myoma, Blue Nevus Syndrome

Myxoma, Spotty Pigmentation, and Endocrine Overactivity

Nevi, Atrial Myxoma, Skin Myxoma, Ephelides Syndrome


Acoustic Neuroma, Cerebellopontine Angle

A benign SCHWANNOMA of the eighth cranial nerve (VESTIBULOCOCHLEAR NERVE), mostly arising from the vestibular branch (VESTIBULAR NERVE) during the fifth or sixth decade of life. Clinical manifestations include HEARING LOSS; HEADACHE; VERTIGO; TINNITUS; and FACIAL PAIN. Bilateral acoustic neuromas are associated with NEUROFIBROMATOSIS 2. (From Adams et al., Principles of Neurology, 6th ed, p673)


Leg Prosthesis
Arm, Artificial
Artificial Limbs
Arm Prosthesis
Limb Prosthesis
Artificial Arm
Leg, Artificial
Artificial Leg
Extremities, Artificial
Limbs, Artificial

Prosthetic replacements for arms, legs, and parts thereof.


Sequence Analysis, Oligonucleotide Array

Oligodeoxyribonucleotide Array Sequence Analysis

Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.


Analgesics, Narcotic
Narcotic Effect
Narcotic Effects
Narcotics
Narcotic Analgesics
Narcotic

Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS.


Small Madagascar Hedgehog
Insectivora
Echinops telfairi
Lesser Hedgehog Tenrec

A terrestrial, nocturnal insectivore of the family Tenrecidae which is not one of the real HEDGEHOGS.


Ion Channel, Chloride
Chlorine Channels
Chloride Channel
Ion Channels, Chloride
Calcium-Activated Chloride Channels
CaCCs
Chloride Channels
Chloride Ion Channels

Cell membrane glycoproteins that form channels to selectively pass chloride ions. Nonselective blockers include FENAMATES; ETHACRYNIC ACID; and TAMOXIFEN.


Aganglionosis, Colonic
Rectosigmoid Aganglionosis
Aganglionosis, Total Colonic
Megacolon, Congenital
Hirschsprung Disease
Colonic Aganglionosis
Congenital Intestinal Aganglionosis
Congenital Megacolon
Hirschsprung's Disease
Total Colonic Aganglionosis
Aganglionosis, Rectosigmoid Colon
Megacolon, Aganglionic
Aganglionic Megacolon

Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.


Deep Venous Thrombosis
Phlebothrombosis
Thrombosis, Venous
Deep-Vein Thrombosis
Venous Thrombosis
Deep-Venous Thrombosis
Thrombosis, Deep Vein
Deep Vein Thrombosis

The formation or presence of a blood clot (THROMBUS) within a vein.


Walnut
Juglans regia
Juglans nigra
Black Walnut
Juglans
English Walnut

A plant genus of the family JUGLANDACEAE that provides the familiar walnut.


Manipulation Therapy
Manipulative Therapies
Manual Therapies
Therapy, Manipulation
Reflexology
Bodywork
Musculoskeletal Manipulations
Rolfing
Craniosacral Massage
Manipulations, Musculoskeletal

Approaches that emphasize manipulation and realignment of the body's structure in order to improve function as well as mental outlook.


SEC61 Translocon
SEC Translocation Channels
SecYEG Complex
SecYEG Translocation Channels
SEC61 Proteins
Sec61 Complex
SecYEG Translocon
SEC61 Protein
SecYEG Complexes
SEC61 Translocation Channels
SecYEG Protein Translocation System
SEC Complexes
SEC Translocons
SEC Translocase
SecY Translocase
SEC61 Translocase
SecYEG Proteins
Sec Protein Translocation Systems
Sec61 Protein Translocation System

The SEC translocase of ENDOPLASMIC RETICULUM membranes. The three subunits are SEC61alpha, SEC61beta, and SEC61gamma. Homologs of these subunits are also found in ARCHAEA,


Computerized Provider Order Entry System

Computerized Physician Order Entry System

Computerized alerting to potential drug-drug interactions.


Pteris esculentum
Pteridium esculentum
Pteris aquilina
Brackenfern
Pteridium aquilinum
Pteridium
Fern, Bracken

A plant genus of the family DENNSTAEDTIACEAE. Members contain ptaquiloside, braxin A1, and braxin B. The name is similar to brake fern (PTERIS).


Urinary Bladder, Overactive
Overactive Detrusor Function
Overactive Detrusor
Overactive Bladder
Overactive Urinary Bladder
Bladder, Overactive

Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present.


Atresia, Biliary
Familial Extrahepatic Biliary Atresia
Intrahepatic Biliary Atresia
Extrahepatic Biliary Atresia
Biliary Atresia
Biliary Atresia, Extrahepatic
Idiopathic Extrahepatic Biliary Atresia
Biliary Atresia, Intrahepatic

Progressive destruction or the absence of all or part of the extrahepatic BILE DUCTS, resulting in the complete obstruction of BILE flow. Usually, biliary atresia is found in infants and accounts for one third of the neonatal cholestatic JAUNDICE.


Oligogenic Traits
Polygenic Inheritance
Complex Traits
Multigenic Inheritance
Multifactorial Inheritance
Polygenic Traits
Polygenic Characters
Multigenic Traits
Complex Inheritance
Oligogenic Inheritance

A pattern of inheritance of a trait that includes the contributions from more than one gene.


Intensive Care
Intensive Care, Surgical
Surgical Intensive Care
Critical Care

Advanced and highly specialized care provided to medical or surgical patients whose conditions are life-threatening and require comprehensive care and constant monitoring. It is usually administered in specially equipped units of a health care facility.


RNA Motifs
Nucleotide Motifs
Nucleotide Motif
DNA Motifs
RNA Motif
DNA Motif

Commonly observed BASE SEQUENCE or nucleotide structural components which can be represented by a CONSENSUS SEQUENCE or a SEQUENCE LOGO.


Bach Flower Remedies
Bach Rescue Remedy
Bach Flower Essences
Bach Flowers
Flower Essences

A combination preparation of several individual Bach flower remedies.


Lipoproteins, VLDL3
Lipoproteins, VLDL
Lipoproteins, VLDL1
Pre-beta-Lipoproteins
Lipoproteins, VLDL2
Prebeta-Lipoproteins
Lipoproteins, VLDL III
Lipoprotein VLDL II
Lipoproteins, VLDL I
Very-Low-Density Lipoproteins

Low density large VLDL particles (60-100 nm).


Atresia, Intestinal
Apple-Peel Intestinal Atresia
Familial Apple Peel Jejunal Atresia
Congenital Intestinal Atresia
Jejunal Atresia
Apple Peel Small Bowel Syndrome
Intestinal Atresia
Apple Peel Syndrome

Congenital obliteration of the lumen of the intestine, with the ILEUM involved in 50% of the cases and the JEJUNUM and DUODENUM following in frequency. It is the most frequent cause of INTESTINAL OBSTRUCTION in NEWBORNS. (From Stedman, 25th ed)


Lateral Ligaments
Collateral Ligaments
Ligaments, Lateral
Ligaments, Collateral

A number of ligaments on either side of, and serving as a radius of movement of, a joint having a hingelike movement. They occur at the elbow, knee, wrist, metacarpo- and metatarsophalangeal, proximal interphalangeal, and distal interphalangeal joints of the hands and feet. (Stedman, 25th ed)


Interferon alpha-beta Receptor IFNAR1 Subunit

IFNAR2.2 Subunit, Interferon alpha-beta Receptor

Interferon alpha-beta Receptor IFNAR2 Subunit

IFNAR2 Subunit, Interferon alpha-beta Receptor

IFNAR2.1 Subunit, Interferon alpha-beta Receptor

IFNAR1 Subunit, Interferon alpha-beta Receptor

The full-length variant of the IFNAR2 chain.


Xicil
Dona
Hespercorbin
Dona S
Glucosamine
Glucosamine Sulfate
2-Amino-2-Deoxyglucose


Cancer of Parotid
Neoplasms, Parotid
Cancer of the Parotid
Parotid Cancer
Parotid Neoplasms


Win-47203
Primacor
Milrinone Lactate
Milrinone
Corotrope
Corotrop

A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the inotropic potency of amrinone.


Pit Viper Venom
Crotalid Venoms
Rattlesnake Venoms
Pit Viper Venoms
Crotactin
Crotalin
Crotamin
Rattlesnake Venom
Crotaline Snake Venom
Crotalid Venom
Crotalotoxin

Venoms from snakes of the subfamily Crotalinae or pit vipers, found mostly in the Americas. They include the rattlesnake, cottonmouth, fer-de-lance, bushmaster, and American copperhead. Their venoms contain nontoxic proteins, cardio-, hemo-, cyto-, and neurotoxins, and many enzymes, especially phospholipases A. Many of the toxins have been characterized.


Thermal Hysteresis Proteins
Antifreeze Glycoproteins
AFGP
Antifreeze Peptides
Antifreeze Glycopeptides
Antifreeze Proteins

Proteins that bind to ice and modify the growth of ice crystals. They perform a cryoprotective role in a variety of organisms.


Oxymorphone HCl
Oxymorphone Hydrochloride
Opana
Oxymorphone
Numorphan

An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092)


Mitogen-Activated Protein Kinase Kinase 6

Stress-Activated Protein Kinase Kinase-3

A mitogen-activated protein kinase kinase with specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES.


Histidine Protein Kinase
Protein-Histidine Tele-Kinase
Protein-Histidine Pros-Kinase
Histone H4 Histidine Kinase
Protein-Histidine Kinase
Sensor Histidine Kinase
Protein Kinase (Histidine), Pros-Kinase
Protein Histidine Pros-Kinase
Histidine Kinase

A member of the transferase superfamily of proteins. In the activated state, protein-histidine kinase autophosphorylates at a histidine residue, subsequently transferring high-energy phosphoryl groups to an aspartate residue of the response-regulator domain, which results in a conformational shift in the effector domain. Histidine kinases mediate signal transduction in a wide range of processes involving cellular adaptation to environmental stress.


Carcinoma, Infiltrating Duct
Mammary Ductal Carcinoma
Carcinoma, Invasive Ductal, Breast
Carcinoma, Ductal, Breast
Carcinoma, Mammary Ductal
Invasive Ductal Carcinoma, Breast

An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST.


Azathioprine Sodium Salt
Azathioprine
Azathioprine Sulfate
Imurel
Imuran
Azathioprine Sodium
Azothioprine
Immuran

An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)


Gabexate Monomethanesulfonate, 14C-Labeled Cpd

A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.


Embolic Infarction, Posterior Cerebral Artery

Thrombotic Infarction, Posterior Cerebral Artery

Posterior Cerebral Artery Thrombotic Infarction

Posterior Cerebral Artery Embolic Infarction

NECROSIS induced by ISCHEMIA in the POSTERIOR CEREBRAL ARTERY distribution system which supplies portions of the BRAIN STEM; the THALAMUS; TEMPORAL LOBE, and OCCIPITAL LOBE. Depending on the size and location of infarction, clinical features include OLFACTION DISORDERS and visual problems (AGNOSIA; ALEXIA; HEMIANOPSIA).


Nutrition Value
Availability, Biological Nutritional
Nutritional Value
Nutritional Availability, Biological
Nutritional Availability, Biologic
Biological Availability, Nutritional
Nutritional Availability
Nutritive Quality
Biologic Availability, Nutritional
Nutritional Biological Availability
Biologic Nutritional Availability
Nutritional Quality
Nutritive Value
Availability, Nutritional Biologic
Nutritional Food Quality

An indication of the contribution of a food to the nutrient content of the diet. This value depends on the quantity of a food which is digested and absorbed and the amounts of the essential nutrients (protein, fat, carbohydrate, minerals, vitamins) which it contains. This value can be affected by soil and growing conditions, handling and storage, and processing.


Focal Clonic Seizures
Motor Partial Seizure Disorder
Seizure Disorder, Hemimotor
Seizure Disorder, Partial, Motor
Motor Seizure Disorder
Hemimotor Seizure Disorder
Focal Tonic Seizures
Partial Epilepsy, Motor
Hemimotor Epilepsy
Epilepsy, Partial, Motor
Focal Motor Epilepsy
Seizure Disorder, Motor
Partial Seizure Disorder, Motor
Versive Seizures

A disorder characterized by recurrent localized paroxysmal discharges of cerebral neurons that give rise to seizures that have motor manifestations. The majority of partial motor seizures originate in the FRONTAL LOBE (see also EPILEPSY, FRONTAL LOBE). Motor seizures may manifest as tonic or clonic movements involving the face, one limb or one side of the body. A variety of more complex patterns of movement, including abnormal posturing of extremities, may also occur.


Complement C5
Complement 5
Precursor C5
Pro-complement 5
Complement C5, Precursor
Pro-C5
Complement Component 5
C5 Complement

C5 plays a central role in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C5 is cleaved by C5 CONVERTASE into COMPLEMENT C5A and COMPLEMENT C5B. The smaller fragment C5a is an ANAPHYLATOXIN and mediator of inflammatory process. The major fragment C5b binds to the membrane initiating the spontaneous assembly of the late complement components, C5-C9, into the MEMBRANE ATTACK COMPLEX.


Kidney Insufficiency, Chronic
Chronic Renal Insufficiency
Renal Insufficiency, Chronic
Chronic Renal Diseases
Chronic Kidney Insufficiency
Chronic Kidney Diseases

Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)


LEPR Protein
OBRb Receptor
OB Receptor
Leptin Receptor
Antigens, CD295
Receptor, Leptin
Receptors, Leptin
OBRa Receptor
Leptin-Binding Protein
CD295 Antigens
Leptin Receptors
Leptin Receptor, Large Isoform
Leptin Receptor, Small Isoform

Isoform B is highly expressed in hypothalamus.


Embryo, Non-Mammalian
Nonmammalian Embryonic Structures
Nonmammalian Embryo
Embryo, Nonmammalian
Embryonic Structures, Nonmammalian
Nonmammalian Embryo Structures
Embryonic Structures, Non-Mammalian

The anatomical parts of a non-mammalian animal during its early stages of development.


Carotid Artery Plaque
Plaque, Ulcerating, Carotid Artery
Carotid Artery Ulcerating Plaque
Carotid Artery Narrowing
Carotid Ulcer
Ulcerating Plaque, Carotid Artery
Stenosis, External Carotid Artery
Stenosis, Common Carotid Artery
Common Carotid Artery Stenosis
Internal Carotid Artery Stenosis
Carotid Artery Stenosis
External Carotid Artery Stenosis
Carotid Stenosis

Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)


Antimanic Effects
Antimanic Agents
Antimanics
Antimanic Drugs
Antimanic Effect

Agents that are used to treat bipolar disorders or mania associated with other affective disorders.


Orbital Inflammatory Pseudotumor
Plasma Cell Granuloma, Orbital
Inflammatory Pseudotumor, Orbital
Pseudotumor, Inflammatory, Orbital
Granuloma, Plasma Cell, Orbital
Orbital Pseudotumor
Orbital Granuloma, Plasma Cell
Inflammatory Pseudotumor of Orbit

A nonspecific tumor-like inflammatory lesion in the ORBIT of the eye. It is usually composed of mature LYMPHOCYTES; PLASMA CELLS; MACROPHAGES; LEUKOCYTES with varying degrees of FIBROSIS. Orbital pseudotumors are often associated with inflammation of the extraocular muscles (ORBITAL MYOSITIS) or inflammation of the lacrimal glands (DACRYOADENITIS).


Optical Mapping, Transmembrane Potential

Optical Mapping, Anatomic Electrical Activity

Anatomic Electrical Activity Optical Mapping

Optical imaging techniques used for recording patterns of electrical activity in tissues by monitoring transmembrane potentials via FLUORESCENCE imaging with voltage-sensitive fluorescent dyes.


Calpactins
Lipocortin
Calcimedins
Annexin B9
Annexins
Annexin A8
Calelectrins
Annexin VIII
Chromobindins
Annexin IX
Annexin A11
Annexin XI
Calpactin
Annexin X
Annexin B10
Lipocortins
Calelectrin

Family of calcium- and phospholipid-binding proteins which are structurally related and exhibit immunological cross-reactivity. Each member contains four homologous 70-kDa repeats. The annexins are differentially distributed in vertebrate tissues (and lower eukaryotes) and appear to be involved in MEMBRANE FUSION and SIGNAL TRANSDUCTION.


An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.


Mormyridae
Electric Fish
Elephantfish
Mormyrid
Elephantfishes

Any species of freshwater African fish of the family Mormyridae, also known as elephantfishes.


Monoblast
Promonocytes
Monocyte-Macrophage Precursor Cells
Monocyte-Macrophage Progenitor Cells
Monoblasts
Promonocyte

Parent cells in the lineage that gives rise to MONOCYTES and MACROPHAGES.


Spicebush
Lindera
Lindera benzoin
Wild Allspice

Lindera benzoin (L.) Blume is known as a source of a balsamic resin called Benzoin which is up to 1/3 BENZOIC ACID.


Puccoon, Red
Sanguinaria
Sanguinaria canadensis
Redroot
Bloodroot
Red Puccoon

A plant genus of the family PAPAVERACEAE, a species of which is the source of sanguinarine extract used in MOUTHWASHES.


Tian-hua-fen
T'ien-hua-fen
Trichosanthin
GLQ223
Compound Q
alpha-Trichosanthin
GLQ-223

Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.


Butcher's Broom
Broom, Butcher's
Ruscus
Ruscus aculeatus

A plant genus of the family Asparagaceae. This should not be confused with Broom or Scotch Broom (CYTISUS) or Desert Broom (BACCHARIS) or Spanish Broom (SPARTIUM) or Brome (BROMUS).


Deficiency Disease, 4-Hydroxyphenol Pyruvic Acid Oxidase

4-Hydroxyphenylpyruvic Acid Oxidase Deficiency

Richner-Hanhart Syndrome, Tyrosinosis, Oculocutaneous Type

Keratosis Palmoplantaris with Corneal Dystrophy

4-Hydroxyphenol Pyruvic Acid Oxidase Deficiency Disease

Deficiency Disease, Tyrosine Transaminase

4 Hydroxyphenylpyruvate Dioxygenase Deficiency Disease

Tyrosine Transaminase Deficiency Disease

A group of disorders which have in common elevations of tyrosine in the blood and urine secondary to an enzyme deficiency. Type I tyrosinemia features episodic weakness, self-mutilation, hepatic necrosis, renal tubular injury, and seizures and is caused by a deficiency of the enzyme fumarylacetoacetase. Type II tyrosinemia features INTELLECTUAL DISABILITY, painful corneal ulcers, and keratoses of the palms and plantar surfaces and is caused by a deficiency of the enzyme TYROSINE TRANSAMINASE. Type III tyrosinemia features INTELLECTUAL DISABILITY and is caused by a deficiency of the enzyme 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE. (Menkes, Textbook of Child Neurology, 5th ed, pp42-3)


An imidobisphosphonate inhibitor of BONE RESORPTION that is used for the treatment of malignancy-related HYPERCALCEMIA; OSTEITIS DEFORMANS; and OSTEOPOROSIS.


Gallium Aluminum Arsenide Lasers
GaAlAs Lasers
Lasers, Quantum Cascade
Semiconductor Diode Lasers
Lasers, Semiconductor
Lasers, Gallium Arsenide
Quantum Cascade Lasers
Lasers, Gallium Aluminum Arsenide
GaAs Lasers
Lasers, GaAlAs
Gallium Arsenide Lasers
Diode Lasers
Lasers, GaAs

Lasers with a semiconductor diode as the active medium. Diode lasers transform electric energy to light using the same principle as a light-emitting diode (LED), but with internal reflection capability, thus forming a resonator where a stimulated light can reflect back and forth, allowing only a certain wavelength to be emitted. The emission of a given device is determined by the active compound used (e.g., gallium arsenide crystals doped with aluminum or indium). Typical wavelengths are 810, 1,060 and 1,300 nm. (From UMDNS, 2005)


Medical Device Designs
Equipment Design
Design, Equipment
Medical Device Design
Device Design, Medical
Design, Medical Device
Device Design
Designs, Medical Device
Device Designs, Medical

Methods and patterns of fabricating machines and related hardware.


Echinacea angustifolia
Echinacea
Coneflower, Purple
Echinacea pallida
Rudbeckia purpurea
Echinacea purpurea
Pale Purple Coneflower

A genus of perennial herbs used topically and internally. It contains echinacoside, GLYCOSIDES; INULIN; isobutyl amides, resin, and SESQUITERPENES.


Pratsiol
Minipress
Prazosin Hydrochloride
Furazosin
Prazosin HCL
Prazosin

A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.


5 beta-Cholestan-3 alpha-ol
5 beta-Cholestan-3 beta-ol
Cholestan-3-ol
5 alpha-Cholestan-3 beta-ol
beta-Cholestanol
Coprosterol
Coprostanol
5 alpha-Cholestan-3 alpha-ol
Cholestanol, (3alpha, 5beta)-Isomer
Dihydrocholesterol
Cholestanol

A cholesterol derivative found in human feces, gallstones, eggs, and other biological matter.


Nanocrystals
Nanocrystalline Materials
Nanoparticles

Any crystalline structure possessing dimensions measured in terms of nanometers.


Heparin derivatives. The term has also been used more loosely to include naturally occurring and synthetic highly-sulphated polysaccharides of similar structure. Heparinoid preparations have been used for a wide range of applications including as anticoagulants and anti-inflammatories and they have been claimed to have hypolipidemic properties. (From Martindale, The Extra Pharmacopoeia, 30th, p232)


Ureter, Cancer Of
Ureter Cancer
Ureteral Cancer
Ureter Neoplasms
Neoplasms, Ureteral
Ureteral Neoplasms
Cancer of Ureter
Neoplasms of Ureter
Cancer of the Ureter

Cancer or tumors of the URETER which may cause obstruction leading to hydroureter, HYDRONEPHROSIS, and PYELONEPHRITIS. HEMATURIA is a common symptom.


Amphiuma
Eel, Congo
Urodela
Salamanders
Caudata

An order of the Amphibia class which includes salamanders and newts. They are characterized by usually having slim bodies and tails, four limbs of about equal size (except in Sirenidae), and a reduction in skull bones.


Isophenylephrine
m-Hydroxynorephedrine
Metaraminol Bitartrate (1:1)
Aramine
Araminol
Hydroxyphenylpropanolamine
m-Hydroxyphenylpropanolamine
Metaradrin
Metaraminol Tartrate
Metaraminol
meta-Hydroxynorephedrine
Metaraminol Bitartrate

A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.


Cranial Nerve XI Injury
Eleventh-Nerve Trauma
Injury, Cranial Nerve XI
Accessory Nerve Avulsion
Spinal Accessory Nerve Contusion
Accessory Neuropathy, Traumatic
Spinal Accessory Nerve Avulsion
Accessory Nerve Contusion
Accessory Nerve Trauma
Eleventh-Nerve Palsy, Traumatic
Injury, Eleventh Cranial Nerve
Eleventh Cranial Nerve Injuries
Eleventh Cranial Nerve Injury
Spinal Accessory Nerve Transection
Accessory Nerve Injuries
Traumatic Eleventh-Nerve Palsy
Accessory Nerve Transection
Spinal Accessory Nerve Trauma
Spinal Accessory Neuropathy, Traumatic
Spinal Accessory Nerve Injury

Traumatic injuries to the ACCESSORY NERVE. Damage to the nerve may produce weakness in head rotation and shoulder elevation.


Mivacurium Chloride
BW-B1090U
BW-B-1090U
BW-B 1090U
Mivacurium
BW B1090U
Mivacron

An isoquinoline derivative that is used as a short-acting non-depolarizing agent.


A naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces parathyroid hormone secretion and decreases serum calcium in the treatment of PARATHYROID DISEASES.


Sexual Infantilism
Infantilism, Sexual
Genital Infantilism
Infantilism, Genital

The permanent lack of SEXUAL DEVELOPMENT in an individual. This defect is usually observed at an age after expected PUBERTY.


Poison Ivy Dermatitis
Toxicodendron Dermatitis
Rhus Dermatitis
Dermatitis, Toxicodendron
Dermatitis, Poison Ivy

An allergic contact dermatitis caused by exposure to plants of the genus Toxicodendron (formerly Rhus). These include poison ivy, poison oak, and poison sumac, all plants that contain the substance urushiol, a potent skin sensitizing agent. (From Dorland, 27th ed)


Cholecystokinin
Cholecystokinin 33
CCK-33
Uropancreozymin
Pancreozymin

A peptide, of about 33 amino acids, secreted by the upper INTESTINAL MUCOSA and also found in the central nervous system. It causes gallbladder contraction, release of pancreatic exocrine (or digestive) enzymes, and affects other gastrointestinal functions. Cholecystokinin may be the mediator of satiety.


Dermodress
Collagen Felt
alpha-Collagen
Pangen
Collagen Fleece
Collagen
Collastat
Collagenfleece
Avicon
Microfibril Collagen Hemostat
Zyderm
Avitene

A topical hemostatic agent prepared from collagen.


A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.


Occlusion Body Matrix Proteins
Granulin Matrix Proteins
Polyhedrin Matrix Proteins
Viral Granulin
Viral Granulin Proteins
Viral Occlusion Body Matrix Proteins
Viral Polyhedra Matrix Proteins
Viral Polyhedrin
Viral Polyhedra Proteins

Proteins that assemble into a crystalline polyhedral or ovicylindrical shape around insect viruses, including BACULOVIRIDAE and CYPOVIRUS.


Oral Glucose Tolerance Test
Glucose Tolerance Test
Oral Glucose Tolerance
Intravenous Glucose Tolerance Test
OGTT
Intravenous Glucose Tolerance

A test to determine the ability of an individual to maintain HOMEOSTASIS of BLOOD GLUCOSE. It includes measuring blood glucose levels in a fasting state, and at prescribed intervals before and after oral glucose intake (75 or 100 g) or intravenous infusion (0.5 g/kg).


Chemical and Drug Induced Liver Injury, Chronic

Chemically-Induced Liver Injury, Chronic

Liver disease lasting six months or more, caused by an adverse effect of a drug or chemical. The adverse effect may be caused by drugs, drug metabolites, chemicals from the environment, or an idiosyncratic response.


Partial Opioid Agonists
Opioid Full Agonists
Opioid Mixed Agonist-Antagonists
Opioids
Analgesics, Opioid
Full Opioid Agonists
Opioid Analgesics
Opioid Partial Agonists

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.


Single Molecule Imaging
Single Molecule Spectroscopy
Single Particle Analysis
Single Particle Spectroscopy
Single Particle Tracking
Single Particle Microscopy
Single Molecule Analysis
Single Molecule Microscopy
Single Molecule Tracking
Single Particle Imaging

High resolution imaging techniques that allow visualization of individual molecules of proteins, lipids, or nucleic acids within cells or tissues.


A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.


Methylglucamine Ioxaglate
P-286 (Contrast Media)
Ioxaglic Acid, Calcium Salt (2:1)
Ioxaglic Acid
Ioxaglic Acid Monosodium Salt
Ioxaglate Sodium
Ioxaglate
P286 (Contrast Media)
Hexabrix
Ioxaglate Meglumine

A low-osmolar, ionic contrast medium used in various radiographic procedures.


Digestive System Disorders
Hepatobiliary Diseases
Digestive System Diseases
Hepatobiliary Disorders

Diseases in any part of the GASTROINTESTINAL TRACT or the accessory organs (LIVER; BILIARY TRACT; PANCREAS).


Hemodynamic Brain Responses
Cortical Hemodynamic Response
Hemodynamic Brain Response
Cortical Hemodynamic Responses
Neurovascular Coupling

Mechanism by which changes in neural activity are tightly associated with regional cortical HEMODYNAMICS and metabolism changes. The association is often inferred from NEUROIMAGING signals (e.g., fMRI; or NIR SPECTROSCOPY).


Citric Acid
Anhydrous Citric Acid
Citric Acid Monohydrate
Uralyt U
Citrate
Citric Acid, Anhydrous

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.


The subject's ability to connect 25 numbered and lettered circles in sequence in a specific length of time. A score of 12 or below is suggestive of organic brain damage.


Methbipyranone
Metyrapone
Methopyrapone
SU 4885
Metopiron
Métopirone
Metopirone

An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.


Infantile Spasms
Symptomatic West Syndrome
Spasmus Nutans
Lightning Attacks
Cryptogenic West Syndrome
Cryptogenic Infantile Spasms
Symptomatic Infantile Spasms
Salaam Attacks
Jackknife Seizures
Nodding Spasm
Salaam Seizures
Hypsarrhythmia
West Syndrome
Spasms, Infantile

An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)


Cardophyllin
Clonofilin
Tari-Dog
Somophyllin
Theophylline Ethylenediamine
Eufilina Venosa
Theophyllamin Jenapharm
Drafilyn
Afonilum
Diaphyllin
Mini-Lix
Aminophylline DF
Corophyllin
Phyllocontin
Aminophyllin
Euphylline
Euphyllin Retard
Eufilina
Mundiphyllin Retard
Aminodur
Novophyllin
Truphylline
Duraphyllin
Aminophylline
Godafilin
Mundiphyllin
Euphyllin
Theophyllin EDA-ratiopharm
Phyllotemp
Theophyllamine
Carine

A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several other applications.


Pleoconial Myopathies
Luft Disease
Mitochondrial Myopathy
Myopathies, Mitochondrial
Megaconial Myopathies
Mitochondrial Myopathies
Luft's Disease

A group of muscle diseases associated with abnormal mitochondria function.


Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They are proteins, found in mite feces or mite extracts, that can cause ASTHMA and other allergic diseases such as perennial rhinitis (RHINITIS, ALLERGIC, PERENNIAL) and atopic dermatitis (DERMATITIS, ATOPIC). More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the above two species, are among the strongest mite immunogens in humans.


Implantable Medication Systems, Programmable

Systems, Programmable Implantable Medication

Programmable Implantable Medication Systems

Medication Systems, Programmable Implantable

Implanted fluid propulsion systems with self-contained power source for providing long-term controlled-rate delivery of drugs such as chemotherapeutic agents or analgesics. Delivery rate may be externally controlled or osmotically or peristatically controlled with the aid of transcutaneous monitoring.


Dolargan
Dolcontral
Operidine EPJ-I
Lidol
Dolin
Meperidine
Pethidine
Lydol
Meperidine Hydrochloride
Dolsin
Dolantin
Dolosal
Demerol
Isonipecain

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.


Light-Harvesting Chlorophyll Protein Complexes

Complexes containing CHLOROPHYLL and other photosensitive molecules. They serve to capture energy in the form of PHOTONS and are generally found as components of the PHOTOSYSTEM I PROTEIN COMPLEX or the PHOTOSYSTEM II PROTEIN COMPLEX.


An HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS.


Navicular Osteochondrosis
Koehler's Disease
Osteochondrosis
Koehler Disease
Osgood-Schlatter Disease

Any of a group of bone disorders involving one or more ossification centers (EPIPHYSES). It is characterized by degeneration or NECROSIS followed by revascularization and reossification. Osteochondrosis often occurs in children causing varying degrees of discomfort or pain. There are many eponymic types for specific affected areas, such as tarsal navicular (Kohler disease) and tibial tuberosity (Osgood-Schlatter disease).


Jaw Neoplasms
Neoplasms, Jaw
Cancer of Jaw
Jaw Cancer
Cancer of the Jaw

Cancers or tumors of the MAXILLA or MANDIBLE unspecified. For neoplasms of the maxilla, MAXILLARY NEOPLASMS is available and of the mandible, MANDIBULAR NEOPLASMS is available.


Radial Nerve Entrapment
Wartenberg Syndrome
Radial Mononeuropathy
Crutch Paralysis
Saturday Night Palsy
Wrist-Drop
Crutch Palsy
Cheiralgia Paresthetica
Superficial Radial Nerve Lesion
Radial Neuropathy
Radial Nerve Palsy
Radial Nerve Diseases
Lesion, Superficial Radial Nerve
Posterior Interosseous Nerve Syndrome
Radial Palsy
Radial Tunnel Syndrome
Supinator Syndrome
Radial Nerve Compression

Disease involving the RADIAL NERVE. Clinical features include weakness of elbow extension, elbow flexion, supination of the forearm, wrist and finger extension, and thumb abduction. Sensation may be impaired over regions of the dorsal forearm. Common sites of compression or traumatic injury include the AXILLA and radial groove of the HUMERUS.


Candimon
Vanobid
Levorin
Candeptin
Candicidin D
Levorine
Candicidin

Mixture of antifungal heptaene macrolides from Streptomyces griseus or Actinomyces levoris used topically in candidiasis. The antibiotic complex is composed of candicidins A, B, C, and D, of which D is the major component.


Filling, Dental Permanent
Dental Fillings, Permanent
Permanent Dental Filling
Fillings, Dental Permanent
Permanent Dental Restoration
Permanent Filling, Dental
Filling, Permanent Dental
Dental Restorations, Permanent
Restorations, Permanent Dental
Permanent Dental Restorations
Fillings, Permanent Dental
Dental Restoration, Permanent
Permanent Fillings, Dental
Dental Permanent Fillings
Dental Filling, Permanent
Restoration, Permanent Dental
Dental Permanent Filling
Permanent Dental Fillings

A restoration designed to remain in service for not less than 20 to 30 years, usually made of gold casting, cohesive gold, or amalgam. (Jablonski, Dictionary of Dentistry, 1992)


Diplopia, Refractive
Polyopsia
Diplopia, Horizontal
Diplopia, Monocular
Diplopia, Unilateral
Diplopia, Intermittent
Diplopia, Vertical
Diplopia, Cortical
Diplopia
Double Vision

A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.


Spectrum Analysis, Mass-Gas Chromatography

A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds.


Protein Carbamylation
Protein Carbamoylation
Carbamoylation
Carbamylation

Non-enzymatic addition of carbamoyl (-CONH2) on protein or amino acid functional groups from isocyanic acid or CARBAMOYL-PHOSPHATE. Carbamylation may induce a structural change that results in a functional loss and serves as a biomarker for protein aging and disease pathophysiology.


Demecolcine
Colchamine
Colcemid
Colcemide
Demecolcine, (+-)-Isomer

An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.


Developmental Articulation Disorders
Misarticulation
Speech Articulation Disorders
Articulation Disorders
Articulation Disorders, Developmental
Phonological Impairments
Unintelligible Articulation
Disarticulation Disorders
Phonology Impairment

Disorders of the quality of speech characterized by the substitution, omission, distortion, and addition of phonemes.


Lurcher Mice
Weaver Mice
Mouse, Neurological Mutant
Reeler Mouse
Nervous Mice
Mouse, Neurologic Mutant
Weaver Mouse
Mice, Neurological Mutants
Lurcher Mouse
Neurological Mutant Mouse
Nervous Mouse
Chakragati Mice
Mice, Neurologic Mutants
Staggerer Mouse
Chakragati Mouse
Neurologic Mutant Mice
Reeler Mice
ckr Mutant Mice
Staggerer Mice

Trangenic mutant mice named for the Sanskrit "to go in circles" (chakragati). They display lateralized circling behaviour, postural asymmetry, and hyperactivity.


Salt-Tolerance
Saline-Tolerance
Salt Adaption
Salt Tolerance
Salinity Tolerance
Salt Adaptation
Salt-Adaption

The ability of organisms to sense and adapt to high concentrations of salt in their growth environment.


Patient Readmission
Hospital Readmissions
Readmission, Hospital
Thirty Day Readmission
30 Day Readmission
Readmissions, Hospital
Hospital Readmission

Subsequent admissions of a patient to a hospital or other health care institution for treatment.


6-D-Tryptophan-Luteinizing Hormone-Releasing Factor (Pig)

A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE with D-tryptophan substitution at residue 6.


Tubulointerstitial Nephritis
Interstitial Nephritis
Nephritis, Tubulointerstitial
Nephritis, Interstitial

Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.


Consciousness, Level Depressed
Semiconsciousness
Consciousness, Level Altered
Altered Level of Consciousness
Depressed Level of Consciousness
Consciousness Disorders

Organic mental disorders in which there is impairment of the ability to maintain awareness of self and environment and to respond to environmental stimuli. Dysfunction of the cerebral hemispheres or brain stem RETICULAR FORMATION may result in this condition.


Correlation Studies
Correlation Study
Correlation of Data

Determination of whether or not two variables are correlated. This means to study whether an increase or decrease in one variable corresponds to an increase or decrease in the other variable.


Calcium-Calmodulin-Dependent Protein Kinase Type 1A

Calcium-Calmodulin-Dependent Protein Kinase Type 1beta

Calcium-Calmodulin-Dependent Protein Kinase Type 1 gamma Isoform

Pregnancy Upregulated Non-Ubiquitously Expressed CaM Kinase

Calcium-Calmodulin-Dependent Protein Kinase Type 1 alpha Isoform

Calcium-Calmodulin-Dependent Protein Kinase Type 1delta

Calcium-Calmodulin-Dependent Protein Kinase Type 1G

Calcium-Calmodulin-Dependent Protein Kinase Type 1gamma

Calcium-Calmodulin-Dependent Protein Kinase Type 1D

Calcium-Calmodulin-Dependent Protein Kinase Type 1B

Calcium-Calmodulin-Dependent Protein Kinase Type 1alpha

Calcium-Calmodulin-Dependent Protein Kinase Type 1 beta Isoform

Calcium-Calmodulin-Dependent Protein Kinase Type 1 delta Isoform

A monomeric calcium-calmodulin-dependent protein kinase subtype that is expressed in a broad variety of mammalian cell types. Its expression is regulated by the action of CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE. Several isoforms of this enzyme subtype are encoded by distinct genes.


Pharmacological Phenomenon
Pharmacologic Phenomenon
Pharmacological Phenomena
Pharmacologic Processes
Pharmacological Processes
Pharmacologic Process
Pharmacological Concepts
Pharmacologic Phenomena

The metabolism of drugs and their mechanisms of action.


Pheniramine
Pheniramine Maleate
Propheniramine
Daneral
Histapyridamine
Prophenpyridamine
Pheniramine Bimaleate
Avil

One of the HISTAMINE H1 ANTAGONISTS with little sedative action. It is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus.


A plant genus of the family SAPINDACEAE that bears sweet fruits. Unusual fatty acids such as cyclopropanoic fatty acids have been identified in the seeds.


Nu-Loraz
Durazolam
Sinestron
Lorazepam
Somagerol
Temesta
Lorazep Von Ct
Laubeel
Témesta
Donix
Lorazepam-Ratiopharm
Sedicepan
Idalprem
Lorazepam-Neuraxpharm
Novo-Lorazem
Ativan
Duralozam
Orfidal Wyeth
WY-4036
Apo-Lorazepam
Lorazepam Medical
Tolid

A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.


Lithotrophy
Autotrophy
Autotrophic Growth
Lithotrophic Processes
Lithotrophic Growth
Autotrophic Processes

The processes by which organisms use simple inorganic substances such as gaseous or dissolved carbon dioxide and inorganic nitrogen as nutrient sources. Contrasts with heterotrophic processes which make use of organic materials as the nutrient supply source. Autotrophs can be either chemoautotrophs (or chemolithotrophs), largely ARCHAEA and BACTERIA, which also use simple inorganic substances for their metabolic energy reguirements; or photoautotrophs (or photolithotrophs), such as PLANTS and CYANOBACTERIA, which derive their energy from light. Depending on environmental conditions some organisms can switch between different nutritional modes (autotrophy; HETEROTROPHY; chemotrophy; or PHOTOTROPHY) to utilize different sources to meet their nutrient and energy requirements.


Methotrexate, Dicesium Salt
Methotrexate, Disodium Salt
Methotrexate
Methotrexate, Sodium Salt
Methotrexate, (D)-Isomer
Methotrexate, (DL)-Isomer
Methotrexate Sodium
Methotrexate Hydrate
Mexate
Amethopterin

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.


SOX-8 Transcription Factor
SOX8 Transcription Factor
Group E SOX Transcription Factors
SOXE Transcription Factors
SOX8 Transcription Factors
SOX10 Transcription Factor
SOX-10 Transcription Factor

A subclass of closely-related SOX transcription factors. Members of this subfamily have been implicated in regulating the differentiation of OLIGODENDROCYTES during neural crest formation and in CHONDROGENESIS.


Decision Support Techniques
Decision Aids
Models, Decision Support
Analysis, Decision
Decision Modeling
Decision Support Technics
Decision Analysis

Mathematical or statistical procedures used as aids in making a decision. They are frequently used in medical decision-making.


Rhizoma Pinelliae
Pinellia ternata
Pinellia
Banha
Ban Xia

A plant genus of the family ARACEAE that contains pinellian (an acidic polysaccharide). The plant is an ingredient of some traditional Asian medicinal mixtures including sho-saiko-to, saiko-keishi-to, and banxia houpu decoction.


Signal Transducer and Activator of Transcription 4

A signal transducer and activator of transcription that mediates cellular responses to INTERLEUKIN-12 in T-LYMPHOCYTES. Stat4 is an important signaling molecule for differentiation in TH1 CELLS.


A centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on behavior.


Civet, Malagasy
Galidia Elegans
Mongoose, Brown-Tailed
Eupleridae
Fossa fossana
Malagasy Mongoose
Salanoia concolor
Mongoose, Ring-Tailed

A family in the suborder Feliformia, order CARNIVORA, comprised of viverrid-like mammals.


Peripheral Nerve Sheath Tumors, Malignant

Malignant Peripheral Nerve Sheath Tumors

A malignant neurilemmoma with nerve sheath differentiation. It is often associated with NEUROFIBROMATOSIS 1 and RHABDOMYOSARCOMA.


Hamsters, Chinese
Hamsters, Grey
Hamsters, Armenian
Cricetulus

A genus of the family Muridae consisting of eleven species. C. migratorius, the grey or Armenian hamster, and C. griseus, the Chinese hamster, are the two species used in biomedical research.


Impromidine Hydrochloride
SKF-92676
Impromidine
SK&F-92676
Impromidine Trihydrochloride
Impromidine Oxalate (1:2)

A highly potent and specific histamine H2 receptor agonist. It has been used diagnostically as a gastric secretion indicator.


Childhood Benign Psychomotor Epilepsy
Epilepsy, Lateral Temporal
Benign Psychomotor Epilepsy, Childhood
Epilepsy, Temporal Lobe
Epilepsy, Benign Psychomotor, Childhood
Epilepsy, Uncinate

A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).


Boswellia serrata
Boswellia carterii
Boswellia sacra
Boswellia
Boswellia carteri

A plant genus of the family BURSERACEAE used medicinally since ancient times. It is a source of salai guggal (the gum resin), boswellic acid (ursane type TRITERPENES), and FRANKINCENSE.


Aldazine
Sonapax
Rideril
Thiozine
Thioridazine HCL
Meleril
Apo-Thioridazine
Mellaril
Melzine
Thioridazine Hydrochloride
Melleretten
Thioridazine-Neurazpharm
Melleryl
Melleril
Thioridazine

A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.


Continued Stay Review
Concurrent Review
Review, Concurrent
Review, Continued Stay

Review of the medical necessity of hospital or other health facility admissions, upon or within a short time following an admission, and periodic review of services provided during the course of treatment.


Precursor-Complement 3
C3 Precursor
Complement Component 3
Pro-Complement 3
Complement C3 Precursor
Complement C3
C3 Complement
Complement 3
Pro-C3

A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase.


Short Hairpin RNA
Piwi-Interacting RNA
siRNA, Trans-Acting
shRNA
RNA, Small Interfering
RNA, Piwi-Interacting
Short Interfering RNA
RNA, Scan
Small Hairpin RNA
Small Scan RNA
piRNA
Trans-Acting siRNA
Repeat-Associated siRNA
siRNA, Repeat-Associated
Small Interfering RNA
tasiRNA
scnRNA
Scan RNA
siRNA

siRNAs, about 26-31 nucleotides in length. They are involved in mammalian GAMETOGENESIS.


Glucuronic Acid, 6-(14)C-labeled, (D)-isomer

A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.


Welfare of Infants
Infant Well-Being
Infant Welfare
Newborn Infant Welfare
Welfare of Newborn Infants
Newborn Infant Well-Being

Organized efforts by communities or organizations to improve the health and well-being of infants.


Essential Tremor
Familial Tremor
Benign Essential Tremor
Hereditary Essential Tremor

A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10)


Nonarteritic Anterior Ischemic Optic Neuropathy

Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)


Interferon Beta, Serine(17)
Extavia
Interferon Beta, Ser(17)
Betaferon
Beta-IFN-1b
Beta-Seron
Interferon beta-1b
Serine(17) Interferon Beta
Betaseron
IFN-Beta Ser
Interferon beta 1b
Ser(17) IFN-beta

A non-glycosylated form of interferon beta-1 that has a serine at position 17. It is used in the treatment of both RELAPSING-REMITTING MULTIPLE SCLEROSIS and CHRONIC PROGRESSIVE MULTIPLE SCLEROSIS.


Regurgitation, Gastric
Laryngopharyngeal Reflux
Supraesophageal Gastric Reflux
Supraesophageal Gastric Reflux (SEGR)

GASTROESOPHAGEAL REFLUX wherein the retrograde flow passes through the UPPER ESOPHAGEAL SPHINCTER


Receptor, Growth Hormone
Receptors, Growth Hormone
Somatotropin Receptors
Growth Hormone Receptors
Somatomammotropin Receptor
Growth Hormone Receptor
Receptors, Somatotropin
Receptors, Somatomammotropin
Somatotropin Receptor
Somatomammotropin Receptors

Cell surface proteins that bind GROWTH HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells. Activation of growth hormone receptors regulates amino acid transport through cell membranes, RNA translation to protein, DNA transcription, and protein and amino acid catabolism in many cell types. Many of these effects are mediated indirectly through stimulation of the release of somatomedins.


Cancer of the Appendix
Appendix Cancer
Cancer, Appendiceal
Cancer of Appendix
Neoplasms, Appendiceal
Appendiceal Cancer
Appendiceal Neoplasms


Lisdexamfetamine Dimesylate
NRP104
Vyvanse
NRP-104
Elvanse
Lis-dexamfetamine Dimesylate
Lisdexamfetamine

A dextroamphetamine drug precursor that also functions as a CENTRAL NERVOUS SYSTEM STIMULANT and DOPAMINE UPTAKE INHIBITOR and is used in the treatment of ATTENTION DEFICIT HYPERACTIVITY DISORDER.


Chronic Primary Open Angle Glaucoma
Glaucoma Simplex
Glaucoma, Compensated
Glaucoma, Simple
Glaucoma, Secondary Open Angle
Primary Open Angle Glaucoma
Glaucoma, Open-Angle
Secondary Open Angle Glaucoma
Glaucoma, Primary Open Angle
Glaucoma, Pigmentary
Glaucoma, Compensative
Glaucoma, Open Angle
Open-Angle Glaucoma

Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris.


Frameshift Suppressor Genes
Genes, Nonsense Mutation Suppressor
Amber Suppressor Genes
Genes, Ochre Suppressor
Ochre Suppressor Genes
Second-Site Suppressor Genes
Genes, Amber Suppressor
Genes, Frameshift Suppressor
Genes, Suppressor
Nonsense Mutation Suppressor Genes
Suppressor Genes
Genes, Second-Site Suppressor
Genes, Opal Suppressor

Genes that have a suppressor allele or suppressor mutation (SUPPRESSION, GENETIC) which cancels the effect of a previous mutation, enabling the wild-type phenotype to be maintained or partially restored. For example, amber suppressors cancel the effect of an AMBER NONSENSE MUTATION.


Ovis ammon aries
Ovis gmelini musimon
Ovis aries musimon
Sheep, Domestic
Mouflon
Ovis aries

The smallest subspecies of wild sheep, from which domestic sheep are primarily descended.


Manilkara
Sapote
Manilkara zapota
Sapodilla
Sapota zapotilla
Achras zapotilla
Zapote
Lucuma mammosa

A plant genus of the family SAPOTACEAE that bears sweet fruit.


Aspirin, Dipyridamole Drug Combination
Extended-Release Dipyridamole-Aspirin
Asasantin Retard
TX-3301
TX 3301
Asasantin
Aspirin-Dipyridamole Drug Combination
Aggrenox

A drug combination of aspirin and dipyridamole that functions as a PLATELET AGGREGATION INHIBITOR, used to prevent THROMBOSIS and STROKE in TRANSIENT ISCHEMIC ATTACK patients.


Avascular Necrosis Of Femoral Head, Primary

Aseptic or avascular necrosis of the femoral head. The major types are idiopathic (primary), as a complication of fractures or dislocations, and LEGG-CALVE-PERTHES DISEASE.


Small Airway Remodeling
Airway Remodeling
Asthmatic Airway Wall Remodelling
Airway Remodelling
Airway Wall Remodelling
Asthmatic Airway Remodelling
Asthmatic Airway Wall Remodeling
Small Airway Remodelling
Asthmatic Airway Remodeling

Small airway (e.g., BRONCHIOLES) remodeling due to smoking, inhaled irritants, etc.


Aquilegia adoxoides
Tian kui
Semiaquilegia adoxoides
Isopyrum adoxoides
Semiaquilegia

A plant genus of the family RANUNCULACEAE that contains griffonilide, lithospermoside, and magnoflorine.


Neurobiology, Cellular
Neurobiology
Cellular Neurobiology
Neurobiology, Molecular
Molecular Neurobiology

The study of the structure, growth, activities, and functions of NEURONS and the NERVOUS SYSTEM.


Convallaria
Lily of the Valley
Lily-of-the-Valley
Convallaria majalis

A plant genus of the family Asparagaceae that contains CARDIAC GLYCOSIDES.


Atypical Mycobacterial Infection, Disseminated

Atypical Mycobacterial Infection, Familial Disseminated

Atypical Mycobacteriosis, Familial Disseminated

Infections with nontuberculous mycobacteria (atypical mycobacteria): M. kansasii, M. marinum, M. scrofulaceum, M. flavescens, M. gordonae, M. obuense, M. gilvum, M. duvali, M. szulgai, M. intracellulare (see MYCOBACTERIUM AVIUM COMPLEX;), M. xenopi (littorale), M. ulcerans, M. buruli, M. terrae, M. fortuitum (minetti, giae), M. chelonae, M. leprae.


Wavelength Dispersive X-Ray Fluorescence Spectroscopy

Wavelength Dispersive X-Ray Spectrometry

Spectrometry, Particle-Induced X-Ray Emission

Energy Dispersive X-Ray Fluorescence Spectroscopy

Proton Induced X Ray Emission Spectrometry

Particle Induced X Ray Emission Spectrometry

Energy Dispersive X-Ray Fluorescence Spectrometry

Spectrometry, Proton Induced X Ray Emission

Wavelength Dispersive X-Ray Fluorescence Spectrometry

Spectrometry, Particle Induced X Ray Emission

Particle-Induced X-Ray Emission Spectrometry

Wavelength Dispersive X-Ray Spectroscopy

Proton-Induced X-Ray Emission Spectrometry

Spectrometry, Proton-Induced X-Ray Emission

The analysis of the X-rays emitted by matter with energy resolving detectors.


A plant genus of the family BURSERACEAE. Members contain a PODOPHYLLOTOXIN.


Premature Rupture of Membrane (Pregnancy)

Preterm Premature Rupture of Fetal Membranes

Spontaneous tearing of the membranes surrounding the FETUS any time before the onset of OBSTETRIC LABOR. Preterm PROM is membrane rupture before 37 weeks of GESTATION.


Derivatives of OXALIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that are derived from the ethanedioic acid structure.


Nafti-Puren
Dusodril
Naftilong
Praxilène
Naftilux
Nafti Von Ct
Nafronyl Oxalate
Naftifurin Oxalate
Azunaftil
Nafronyloxalate
Gévatran
LS-121
Artocoron
Di-Actane
Nafronyl
Praxilene
Naftidrofuryl
Nafti-Ratiopharm

A drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1310) It may also be an antagonist at 5HT-2 serotonin receptors.


Manufacturing Plants
Manufacturing and Industrial Facilities
Manufacturing Facilities
Industrial Factories
Industrial Facilities
Manufacturing Factories
Industrial Plants
Manufacturing and Industrial Plants

Places provided for the processing, fabrication, assembly, and production of a line of products, services, commodities, or merchandise.


Fructosediphosphatase Deficiency
Fructose-1,6-Bisphosphatase Deficiency
Deficiency, Hexosediphosphatase
Fructose 1,6 Diphosphatase Deficiency
Hexosediphosphatase Deficiency
Fructose-1,6-Diphosphatase Deficiency
Fructose-Biphosphatase Deficiency

An autosomal recessive fructose metabolism disorder due to absent or deficient fructose-1,6-diphosphatase activity. Gluconeogenesis is impaired, resulting in accumulation of gluconeogenic precursors (e.g., amino acids, lactate, ketones) and manifested as hypoglycemia, ketosis, and lactic acidosis. Episodes in the newborn infant are often lethal. Later episodes are often brought on by fasting and febrile infections. As patients age through early childhood, tolerance to fasting improves and development becomes normal.


Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.


Environmental Impacts
Impact, Environmental
Environmental Impact
Impacts, Environmental
Environment

The external elements and conditions which surround, influence, and affect the life and development of an organism or population.


Jaguars
Panthera pardus
Panthera
Black Panther
Panthera onca
Leopard

The species Panthera pardus, not to be confused with leopards in other genera.


Elettaria cardamomum
Elettaria
Cardamon
Amomum cardamomum
Cardamom

A plant genus of the family ZINGIBERACEAE, order Zingiberales, subclass Zingiberidae. Elettaria cardamomum (L.) Maton is the source of Cardamom used in SPICES.


Receptor, Melatonin, MT3
Receptor, Mel1c
Melatonin Receptors
Mel(1c) Receptor
MT3 Receptor
Receptors, Melatonin
Receptor, Melatonin, 1C
Receptor, Melatonin
Melatonin MT3 Receptor

A melatonin receptor subtype found in non-mammalian species.


Aortic Rupture
Aortic Aneurysm, Ruptured
Ruptured Aortic Aneurysm

The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.


Megakaryoblasts
Promegakaryocytes
Megakaryoblast
Megakaryocyte Progenitor
Megakaryocyte Progenitors
Megakaryocyte Progenitor Cells

The parent cells that give rise to cells in the MEGAKARYOCYTE lineage, and ultimately BLOOD PLATELETS.


Carbimazole Henning
Neo-Thyreostat
Carbimazole
Neomercazole
Neo Tomizol
Neo-Mercazole

An imidazole antithyroid agent. Carbimazole is metabolized to METHIMAZOLE, which is responsible for the antithyroid activity.


Computer-Assisted Surgery
Image-Guided Surgery
Computer-Aided Surgery
Surgery, Image-Guided
Surgery, Computer-Assisted

Interactively combining prior CT scans or MRI images with real-time video to guide instruments during surgery.


School Burnout
Caregiver Burnout
Burnout, School
Burn-out
Burnout, Psychological
Burnout, Student
Student Burnout
Burn-out Syndrome
Psychological Burn-out
Caregiver Exhaustion
Burnout Syndrome
Burnout, Caregiver
Burnout

An excessive reaction to stress caused by one's environment that may be characterized by feelings of emotional and physical exhaustion, coupled with a sense of frustration and failure.


Blindness, Cortical
Psychic Denial of Blindness
Transient Anton's Syndrome
Blindness, Cortical, Post-Ictal
Blindness, Cortical, Transient
Anton-Babinski Syndrome
Anton Syndrome
Anton's Syndrome
Reversible Cortical Blindness

Total loss of vision in all or part of the visual field due to bilateral OCCIPITAL LOBE (i.e., VISUAL CORTEX) damage or dysfunction. Anton syndrome is characterized by the psychic denial of true, organic cortical blindness. (Adams et al., Principles of Neurology, 6th ed, p460)


Multiple Symmetrical Lipomatosis
Lipomatosis Familial Benign Cervical
Madelung's Neck
Lipomatosis, Nodular Circumscribed
Nodular Circumscribed Lipomatosis
Lipomatosis, Multiple Symmetrical
Madelung's Disease
Lipomatosis, Familial Benign Cervical
Madelung Neck
Lipomatosis, Multiple Symmetric
Madelung Disease
Lipodystrophy, Cephalothoracic

A condition characterized by the growth of unencapsulated masses of ADIPOSE TISSUE symmetrically deposited around the neck, shoulders, or other sites around the body.


Care, Prepaid Dental
Plan, Dental Care
Plans, Dental Care
Dental Insurance
Insurance, Dental
Dental Care Plan
Prepaid Dental Care

Insurance providing coverage for dental care.


A benzamide derivative that is used as an antipsychotic agent for the treatment of schizophrenia. It is also used as an antidepressive agent.


Dynamin, Alanine44 Substituted With Lysine

Dynamins that contain an alanine in position 44 instead of lysine. The amino acid substitution causes the protein to be GTPase-deficient and unable to function normally in the cell. GTPase-deficient dynamins are used experimentally to study dynamin function.


Paracentral Thalamic Nucleus
Centromedian Thalamic Nucleus
Parafascicular Nucleus Of The Thalamus
Central Medial Thalamic Nucleus
Central Lateral Nucleus
Centromedian Nucleus
Nucleus Centrum Medianum
Rostral Intralaminar Nuclei
Reticulate Nuclei of Thalamus
Nucleus Paracentralis
Intralaminar Nuclear Group
Centrum Medianum
Paracentral Nucleus
Central Lateral Thalamic Nucleus
Central Medial Nucleus
Central Dorsal Thalamic Nucleus
Centre Median Nucleus
Central Dorsal Nucleus
Parafascicular Nucleus
Nucleus Parafascicularis
Nucleus Parafascicularis Thalami
Intralaminar Thalamic Nuclei
Parafascicular Thalamic Nucleus
Interlaminar Nuclei of Thalamus

Cell groups within the internal medullary lamina of the THALAMUS. They include a rostral division comprising the paracentral, central lateral, central dorsal, and central medial nuclei, and a caudal division composed of the centromedian and parafascicular nuclei.


Apolipoproteins E
Apo E Isoproteins
Apo E
ApoE
Apo-E
Apoprotein (E)
Apolipoprotein E Isoproteins
Apoproteins E

A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.


Arctic Fox
Vulpes
Foxes
Urocyon
Pseudalopex
Alopex

Any of several carnivores in the family CANIDAE, that possess erect ears and long bushy tails and are smaller than WOLVES. They are classified in several genera and found on all continents except Antarctica.


Epidermolysis Bullosa Simplex, Cockayne-Touraine Type

Epidermolysis Bullosa Simplex, Weber-Cockayne Type

Epidermolysis Bullosa Herpetiformis Dowling-Meara

Epidermolysis Bullosa Herpetiformis, Dowling-Meara Type

Weber-Cockayne Type Epidermolysis Bullosa Simplex

Epidermolysis Bullosa Herpetiformis Dowling Meara

Epidermolysis Bullosa Simplex, Dowling-Meara Type

Epidermolysis Bullosa Simplex, Localized

Epidermolysis Bullosa Simplex, Koebner Type

Epidermolysis Bullosa Simplex, Generalized

A form of epidermolysis bullosa characterized by serous bullae that heal without scarring. Mutations in the genes that encode KERATIN-5 and KERATIN-14 have been associated with several subtypes of epidermolysis bullosa simplex.


Carbamoyl Phosphate Synthase (Ammonia) Deficiency Disease

Carbamoylphosphate Synthetase I Deficiency Disease

Carbamoyl-Phosphate Synthase I Deficiency Disease (Ornithine Carbamoyl Phosphate Deficiency)

Carbamoyl Phosphate Synthetase I Deficiency, Hyperammonemia Due To

Carbamoylphosphate Synthetase 1 Deficiency Disease -

Hyperammonemia Due to Carbamoyl Phosphate Synthetase 1 Deficiency

Carbamyl Phosphate Synthetase (CPS) Deficiency

Carbamyl Phosphate Synthetase Deficiency Disease

Carbamyl-Phosphate Synthetase I Deficiency Disease

Carbamoyl-Phosphate Synthase 1 Deficiency Disease (Ornithine Carbamoyl Phosphate Deficiency)

Carbamoyl Phosphate Synthase 1 Deficiency

Carbamyl-Phosphate Synthetase 1 Deficiency Disease

Carbamoyl-Phosphate Synthetase I Deficiency Disease

A urea cycle disorder manifesting in infancy as lethargy, emesis, seizures, alterations of muscle tone, abnormal eye movements, and an elevation of serum ammonia. The disorder is caused by a reduction in the activity of hepatic mitochondrial CARBAMOYL-PHOSPHATE SYNTHASE (AMMONIA). (Menkes, Textbook of Child Neurology, 5th ed, pp50-1)


Educational Activities
Literacy Programs
Education
Workshops
Activities, Educational
Training Programs

Acquisition of knowledge as a result of instruction in a formal course of study.


DNA Sequencing
Analysis, DNA Sequence
Determination, DNA Sequence
Sequence Determinations, DNA
Sequence Analysis, DNA
DNA Sequence Determinations
DNA Sequence Analysis
Sequence Determination, DNA
Determinations, DNA Sequence
DNA Sequence Determination

A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.


G1 Restriction Point
G1 Cell Cycle Arrest
G1 Phase Cell Cycle Checkpoints
G1 Cell Cycle Checkpoints
G1 Phase Checkpoints
G1 Phase Restriction Point
START Cell Cycle Checkpoint
G1-S Phase Cell Cycle Checkpoint


Cystic Fibrosis
Pancreatic Cystic Fibrosis
Fibrocystic Disease of Pancreas
Cystic Fibrosis of Pancreas
Pulmonary Cystic Fibrosis
Mucoviscidosis

An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.


Neoplasms, Pharyngeal
Neoplasms, Pharynx
Cancer of the Pharynx
Pharyngeal Cancer
Pharyngeal Neoplasms
Pharynx Neoplasms
Pharnyx Cancer
Cancer of Pharynx


Renal Glomerulus Mesangial Cells
Mesangial Cells, Kidney
Glomerular Mesangial Cells
Lacis Cells
Renal Mesangial Cells
Extraglomerular Mesangial Cells
Mesangial Cells

Smooth muscle-like cells adhering to the wall of the small blood vessels of the KIDNEY at the glomerulus and along the vascular pole of the glomerulus in the JUXTAGLOMERULAR APPARATUS. They are myofibroblasts with contractile and phagocytic properties. These cells and their MESANGIAL EXTRACELLULAR MATRIX constitute the GLOMERULAR MESANGIUM.


Glutamate Plasma Membrane Transporter Proteins

Neurotransmitter Transport Proteins, Glutamate-Specific

Excitatory Amino Acid Transporter Proteins

Glutamate Plasma Membrane Transport Proteins

Excitatory Amino Acid Transport Proteins

A family of plasma membrane neurotransmitter transporter proteins that couple the uptake of GLUTAMATE with the import of SODIUM ions and PROTONS and the export of POTASSIUM ions. In the CENTRAL NERVOUS SYSTEM they regulate neurotransmission through synaptic reuptake of the excitatory neurotransmitter glutamate. Outside the central nervous system they function as signal mediators and regulators of glutamate metabolism.


Unlike testosterone, which is a flat molecule, its 8-isomer has a folded conformation.


Apo-Prednisone
Pronisone
Ultracorten
Prednison Galen
Predniment
Cortancyl
Liquid Pred
Encorton
Winpred
Cutason
Orasone
Kortancyl
Dacortin
Panasol
Decortin
Prednisone
Enkortolon
Meticorten
Cortan
Deltasone
Panafcort
Decortisyl
Encortone
delta-Cortisone
Prednison Acsis
Predni Tablinen
Rectodelt
Sterapred
Prednidib
Dehydrocortisone
Prednison Hexal
Sone

A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.


Emergency Health Services
Medical Services, Emergency
Emergency Services, Medical
Emergency Care
Services, Emergency Medical
Prehospital Emergency Care
Emergency Medical Services
Emergicenters
Emergency Care, Prehospital

Services specifically designed, staffed, and equipped for the emergency care of patients.


Laundry Detergent Pods
Syndet
Detergent Pods
Synthetic Detergent
Cleansing Agents
Laundry Pods
Detergents

Single-use containers of detergent used for laundry and dish washing.


UTP
Uridine Triphosphate
Magnesium Uridine Triphosphate
Mg-UTP
Magnesium UTP

Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.


Ultrahigh Frequency Waves
Extremely High Frequency Radio Waves
Microwaves
EHF Waves
Microwave Radiation

That portion of the electromagnetic spectrum from the UHF (ultrahigh frequency) radio waves and extending into the INFRARED RAYS frequencies.


Cephaelis
Cephaelis ipecacuanha
Psychotria ipecacuanha
Uragoga


Intercellular Fluid
Interstitial Fluid
Extracellular Fluid

The fluid in spaces between the tissue cells, constituting about 16% of the weight of the body; closely similar in composition to LYMPH. (On-Line Medical Dictionary [Internet]. University of Newcastle upon Tyne (UK): The CancerWEB Project, Academic Medical Publishing; c1997-2003 [cited 2003 May 1]. Available from: http://cancerweb.ncl.ac.uk/omd/.)


Quinoctal
Quinine Lafran
Surquina
Quinine
Quinine Sulfate
Strema
Legatrim
Quinine Sulphate
Myoquin
Quinine Bisulfate
Quinamm
Quinine-Odan
Quinbisan
Quinine Hydrochloride
Quinimax
Quinsul
Quinbisul
Quindan
Quinson
Biquinate

An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.


Aviation Medicine
Medicine, Space
Space Medicine
Aerospace Medicine
Medicine, Aerospace
Medicine, Aviation

That branch of medicine dealing with the studies and effects of flight through the atmosphere or in space upon the human body and with the prevention or cure of physiological or psychological malfunctions arising from these effects. (from NASA Thesaurus)


Sulfobromophthalein Disodium
Bromsulphalein
Sulfobromophthalein Sodium
Bromthalein
Tetrabromsulphthalein
Bromosulfophthalein
Bromosulphthalein
Sulfobromophthalein

A phenolphthalein that is used as a diagnostic aid in hepatic function determination.


Cultured Foods
Fermented Beverages
Fermented Foods and Beverages
Fermented Foods

Foods and beverages that are prepared by using microorganisms to convert their components into various FERMENTATION end products. Some pickled foods are considered fermented foods as their pickling results from the microbial production of LACTIC ACID.


Aerosol Therapy, Drug
Inhalation Administration
Inhalation Drug Administration
Respiratory Drug Administration
Administration, Inhalation
Drug Aerosol Therapy
Aerosol Drug Therapy
Drug Therapy, Aerosol
Drug Administration, Respiratory
Drug Administration, Inhalation
Inhalation of Drugs

The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.


Microorganism Z
Simkaniaceae
Parachlamydiaceae
Criblamydiaceae
Rhabdochlamydia
Waddliaceae
Chlamydiales

A family of the order CHLAMYDIALES that naturally infects amoeba.


Gelada Baboon
Baboon, Gelada
Gelada
Theropithecus gelada
Theropithecus

A genus of Old World monkeys of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, that inhabits the mountainous regions of Ethiopia. The genus consists of only one species, Theropithecus gelada.


Alopecia, Androgenetic
Alopecia, Male Pattern
Androgenetic Alopecia
Male Pattern Baldness
Androgenic Alopecia
Female Pattern Baldness
Baldness
Baldness, Male Pattern
Alopecia
Pattern Baldness
Alopecia Cicatrisata
Hair Loss
Pseudopelade

Absence of hair from areas where it is normally present.


Acrocephaly, Skull Asymmetry, and Mild Syndactyly

Dysostosis Craniofacialis with Hypertelorism

Congenital craniostenosis with syndactyly.


Methylergol Carbamide
Lysenyl
Lisuride Maleate
Lisuride Hydrochloride
Lisuride Phosphate (1:1)
Dopergine
Revanil
Lisuride
Lisuride Mesylate
Arolac
Lysurid
Lisuride Maleate (1:1)
Lisuride Maleate, (8beta)-Isomer
Cuvalit
Lisuride, (8alpha)-(+-)-Isomer
Dopergin
Lysuride Hydrogen Maleate

An ergot derivative that acts as an agonist at dopamine D2 receptors (DOPAMINE AGONISTS). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (SEROTONIN RECEPTOR AGONISTS).


Benzene Hexachloride
Hexachlorocyclohexane
Scabisan
gamma-HCH
Gamma-666
Delitex
gamma-Hexachlorocyclohexane
gamma-Benzene Hexachloride
Lindane
Epsilon-hexachlorocyclohexane
PMS-Lindane
Eta-hexachlorocyclohexane
Kwell
Tetocid
Jacutin
Gammexane
Zeta-hexachlorocyclohexane
Scabecid
BHC Insecticide
Scabene
Hexachlorane

An organochlorine insecticide made up of greater than 99% gamma-Hexachlorocyclohexane. It has been used as a pediculicide and scabicide, and shown to cause cancer.


Spinal Cord Ventral Horn Interneuron Renshaw

Ipsilateral glycinergic inhibitory interneurons of the SPINAL CORD VENTRAL HORN which modulate recurrent firing of MOTOR NEURONS. They develop from embryonic progenitor domain V1.Ia inhibitory interneurons which also originate from V1 are responsible for reciprocal inhibition of MOTONEURONS.


Coliphage fd
fd Phage
Bacteriophage fd
Bacteriophage M13
Coliphage M13
Phage fd
M13 Phage
Phage M13
Enterobacteria phage M13
Enterobacteria phage fd

Temperate bacteriophage of the genus INOVIRUS which infects enterobacteria, especially E. coli. It is a filamentous phage consisting of single-stranded DNA and is circularly permuted.


Peptide Receptors
Receptors, Peptide Hormones
Peptide Hormone Receptors
Receptors, Peptide
Peptide Receptor
Receptors, Peptides
Peptide Hormone Receptor

Cell surface receptors that bind peptide messengers with high affinity and regulate intracellular signals which influence the behavior of cells.


Ocular Vestibular Evoked Myogenic Potentials

Cervical Vestibular Evoked Myogenic Potentials

Recorded electrical responses from the neck muscles following stimulation of the EAR VESTIBULE.


A pyrazole derivative and selective CYCLOOXYGENASE 2 INHIBITOR that is used to treat symptoms associated with RHEUMATOID ARTHRITIS; OSTEOARTHRITIS and JUVENILE ARTHRITIS, as well as the management of ACUTE PAIN.


MspI Endonuclease
Endonuclease HpaII
SecII Endonuclease
Deoxyribonuclease MspI
HapII Endonuclease
BsuF Endonuclease
Deoxyribonuclease HpaII
DNA Restriction Enzyme HpaII
Endodeoxyribonuclease HpaII

One of the Type II site-specific deoxyribonucleases (EC 3.1.21.4). It recognizes and cleaves the sequences C/CGG and GGC/C at the slash. HpaII is from Haemophilus parainfluenzae. Several isoschizomers have been identified. EC 3.1.21.-.


Chronic Kidney Disease-Mineral and Bone Disorder

Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.


Military Hospitals
Hospitals, Air Force
Army Hospitals
Navy Hospitals
Air Force Hospitals
Hospitals, Army
Hospitals, Military
Hospitals, Navy

Hospitals which provide care for the military personnel and usually for their dependents.


Hydroxyampicillin
Clamoxyl G.A.
Amoxicillin Anhydrous
Amoxicillin Sodium
Penamox
Amoxicillin, (R*)-Isomer
Clamoxyl
Amoxicillin Trihydrate
Polymox
Actimoxi
Amoxicillin Monopotassium Salt
Clamoxyl Parenteral
Wymox
Amoxicillin Monosodium Salt
Amoxicilline
Amoxil
Amoxycillin
Trimox
BRL-2333
Amoxicillin

A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.


Intravascular Erythrocyte Aggregation
Erythrocyte Aggregation
Rouleaux Formation, Erythrocyte
Intravascular Agglutination
Agglutination, Intravascular
Erythrocyte Aggregation, Intravascular

Aggregation of ERYTHROCYTES in vivo, caused by specific interactions such as those induced by antibodies.


A purine and quinazoline derivative that functions as an INCRETIN and DIPEPTIDYL-PEPTIDASE IV INHIBTOR. It is used as a HYPOGLYCEMIC AGENT in the treatment of TYPE II DIABETES MELLITUS.


5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase

A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.


Lateral Femoral Cutaneous Nerve Entrapment

Disease involving the femoral nerve. The femoral nerve may be injured by ISCHEMIA (e.g., in association with DIABETIC NEUROPATHIES), nerve compression, trauma, COLLAGEN DISEASES, and other disease processes. Clinical features include MUSCLE WEAKNESS or PARALYSIS of hip flexion and knee extension, ATROPHY of the QUADRICEPS MUSCLE, reduced or absent patellar reflex, and impaired sensation over the anterior and medial thigh.


Dynactin-4
Dynamitin Protein
p22 Dynactin Light Chain
p150(Glued)
Dynactin Subunit 2
Dynactin-3
Dynactin
Dynactin Subunit 3
Dynactin Complex
Dynactin 1
Dynactin Subunit 1
Dynein Activator Protein
Dynactins
150 kDa Dynein-Associated Protein
Dynactin-2
Dynactin Subunit 4
Dynein-Associated Protein, 150-kDa
p50 Dynamitin

A multi-subunit protein of EUKARYOTIC CELLS. It functions in bidirectional intracellular transport of ORGANELLES and CYTOPLASMIC VESICLES by linking them to DYNEIN and KINESIN.


Spherosomes
Adiposomes
Oil Bodies
Lipid Droplets
Oleosomes
Lipid Storage Bodies
Lipid Bodies

Lipid-containing organelles found in plant tissues.  They primarily contain TRIGLYCERIDES bound by a phospholipid monolayer.


Transplantation, Bone Marrow Cell
Bone Marrow Transplantation
Bone Marrow Cell Transplantation
Transplantation, Bone Marrow
Grafting, Bone Marrow

The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.


Thiophos
Ethyl Parathion
Phosphostigmine
Thiofos
Parathion
E-605

A highly toxic cholinesterase inhibitor that is used as an acaricide and as an insecticide.


Jack-in-the-Pulpit
Arisaema
Arisaema dracontium
Dragonroot
Arisaema triphyllum
Green Dragon
Dragon, Green

A plant genus of the family ARACEAE. It has a stemless, tuberous root.


Accidents, Nuclear
Accidents, Nuclear Reactor
Radioactive Hazard Release
Radiation Accident
Accidents, Radiation
Nuclear Reactor Accidents
Radiation Accidents
Nuclear Accidents
Accident, Radiation

Accidental dispersal of radioactive materials from a radiation source. Accidents at nuclear reactors can involve large groups of the population from dispersion of radioactivity into the environment and through fallout or a few individuals with high injurious doses.


Gourd, Snake
Snake Gourd
Trichosanthes kirilowii
Trichosanthes

A plant species of the family CUCURBITACEAE that is a source of TRICHOSANTHIN (a ribosomal inhibitory protein).


Vibrio marinus
Moritella
Moritella marina
Vibrio viscosus
Moritella viscosa

A genus of gram-negative, curved or straight rod-shaped bacteria, in the family ALTEROMONADACEAE. They are chemo-organotrophic, halophilic, and associated with cold marine habitats.


Recessive Genetic Conditions
Genes, Recessive
Conditions, Recessive Genetic
Genetic Conditions, Recessive

Genes that influence the PHENOTYPE only in the homozygous state.


Resynchronization Pacing Therapy, Cardiac

Cardiac Resynchronization Pacing Therapy

Electrical stimulation of the heart by artificial pacemaker leads placed at sites in the RIGHT ATRIUM and both HEART VENTRICLES to treat various cardiac conduction disturbances which interfere with the timing of contraction of the ventricles.


Pro-Cid
Probenecid Weimer
Benemid
Benuryl
Probenecid
Benecid
Probecid

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.


Noonan Syndrome with Multiple Lentigines

An autosomal dominant disorder with an acronym of its seven features (LENTIGO; ELECTROCARDIOGRAM abnormalities; ocular HYPERTELORISM; PULMONARY STENOSIS; abnormal genitalia; retardation of growth; and DEAFNESS or SENSORINEURAL HEARING LOSS). This syndrome is caused by mutations of PTPN11 gene encoding the non-receptor PROTEIN TYROSINE PHOSPHATASE, type 11, and is an allelic to NOONAN SYNDROME. Features of LEOPARD syndrome overlap with those of NEUROFIBROMATOSIS 1 which is caused by mutations in the NEUROFIBROMATOSIS 1 GENES.


Cancer of Intestines
Intestines Neoplasms
Intestinal Cancer
Intestines Cancer
Neoplasms, Intestinal
Cancer of the Intestines
Intestinal Neoplasms


Myoclonic Jerk
Myoclonus, Sleep
Myoclonus, Eyelid
Myoclonus, Segmental
Myoclonus, Intention
Myoclonic Jerking
Myoclonus, Oculopalatal
Polymyoclonus
Myoclonus, Upper Extremity
Myoclonus Simplex
Myoclonus, Palatal
Myoclonus, Lower Extremity
Myoclonus
Myoclonus, Nocturnal
Myoclonus, Action

Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may be a feature of some CENTRAL NERVOUS SYSTEM DISEASES; (e.g., EPILEPSY, MYOCLONIC). Nocturnal myoclonus is the principal feature of the NOCTURNAL MYOCLONUS SYNDROME. (From Adams et al., Principles of Neurology, 6th ed, pp102-3).


Moniliasis, Vulvovaginal
Vaginal Yeast Infection
Candidiasis, Genital
Candidiasis, Vulvovaginal
Genital Vulvovaginal Candidiasis
Vaginal Yeast Infections
Vaginitis, Monilial

Infection of the VULVA and VAGINA with a fungus of the genus CANDIDA.


Sv Radiation Dose Equivalent
Dosage, Radiation
Sievert Units
Gray Units
Gy Radiation
Radiation Dosage

One sievert is the dose equivalent of radiation exposure imparted by ionizing X-RAY (roentgen rays) or other radiation undergoing an energy loss of 1 joule per kilogram of body tissue (l gray). One sievert is equivalent to 100 rem (roentgen equivalent in man).


Demyelinating Autoimmune Diseases, Spinal Cord

Autoimmune Demyelinating Diseases, Spinal Cord

Spinal Cord Demyelinating Autoimmune Diseases

Autoimmune Diseases, Demyelinating, Brain

Demyelinating Autoimmune Diseases, Cerebral

Cerebral Demyelinating Diseases, Autoimmune

Demyelinating Autoimmune Diseases, Brain

Demyelinating Autoimmune Diseases, Central Nervous System

Autoimmune Demyelinating Diseases, Central Nervous System

Autoimmune Demyelinating Diseases, Cerebral

Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.


Dyfonate
Fonofos
Dyphonate
Stauffer N-2790

An organothiophosphorus cholinesterase inhibitor that is used as an insecticide.


Dermatitis, Occupational
Dermatosis, Industrial
Occupational Dermatitis
Industrial Dermatosis

A recurrent contact dermatitis caused by substances found in the work place.


Nutritional Physiology Phenomenon
Nutrition Physiological Concepts
Nutritional Physiological Phenomenon
Nutritional Physiological Phenomena
Nutrition Physiological Phenomenon
Nutrition Process
Nutritional Phenomena
Nutritional Physiology
Nutritional Processes
Nutrition Physiology
Nutrition Processes
Nutritional Physiology Phenomena
Nutritional Process
Nutrition Physiological Phenomena
Nutrition Phenomena
Nutritional Physiology Concepts

Observable or measurable characteristics of nutrition.


Coatomer delta Subunit
delta-COP Protein
Coatomer beta Subunit
Archain
epsilon-COP
ARCN1 Protein
Coatomer gamma Subunit
Ret1 Protein
beta-COP
alpha-COP
Coatomer zeta Subunit
zeta-COP
Coatomer epsilon Subunit
Coatomer Subunit epsilon-COP
Coatomer Protein
delta-COP
p102 Protein (Golgi)
HEP-COP
Coatomer alpha Subunit

A 700-kDa cytosolic protein complex consisting of seven equimolar subunits (alpha, beta, beta', gamma, delta, epsilon and zeta). COATOMER PROTEIN and ADP-RIBOSYLATION FACTOR 1 are principle components of COAT PROTEIN COMPLEX I and are involved in vesicle transport between the ENDOPLASMIC RETICULUM and the GOLGI APPARATUS.


Gallstones, Common Bile Duct
Biliary Calculi
Gall Stones
Gallstones
Gall Stones, Common Bile Duct
Common Bile Duct Gallstones
Common Bile Duct Calculi
Biliary Calculi, Common Bile Duct
Common Bile Duct Gall Stones
Gall Stone

Gallstones that are present in the COMMON BILE DUCT, but are usually formed in the GALLBLADDER.


Gallbladder Inflammation
Cholecystitis
Empyema, Gallbladder
Empyema, Gall Bladder


Tropomyosin
alpha-Tropomyosin
Paratropomyosin
Paramyosin
gamma-Tropomyosin
Miniparamyosin
Tropomyosin Mg
beta-Tropomyosin

A protein found in the thin filaments of muscle fibers. It inhibits contraction of the muscle unless its position is modified by TROPONIN.