Electrophoresis in which paper is used as the diffusion medium. This technique is confined almost entirely to separations of small molecules such as amino acids, peptides, and nucleotides, and relatively high voltages are nearly always used.


An abnormally low volume of blood circulating through the body. It may result in hypovolemic shock (see SHOCK).


The study of systems, particularly electronic systems, which function after the manner of, in a manner characteristic of, or resembling living systems. Also, the science of applying biological techniques and principles to the design of electronic systems.


Terms or expressions which provide the major means of access by subject to the bibliographic unit.


Aromatic organic compounds with the chemical formula C6H5Cln.


Food BEVERAGES that are used as nutritional substitutes for MILK.


Loss of water by diffusion through the skin and by evaporation from the respiratory tract.


Small computers that lack the speed, memory capacity, and instructional capability of the full-size computer but usually retain its programmable flexibility. They are larger, faster, and more flexible, powerful, and expensive than microcomputers.


A genus of gram-positive, anaerobic bacteria in the family Thermoanaerobacteriaceae. Cultures consist of rods interspersed with coccoid cells.


A mechanism of communication within a system in that the input signal generates an output response which returns to influence the continued activity or productivity of that system.


A naturally radioactive element with atomic symbol Rn, and atomic number 86. It is a member of the noble gas family found in soil, and is released during the decay of RADIUM.


A plant genus of the family FABACEAE. It is distinct from Sweet Clover (MELILOTUS), from Bush Clover (LESPEDEZA), and from Red Clover (TRIFOLIUM).


A species of Bacteroides that is a major constituent of the human GUT MICROBIOTA. It normally produces enzymes important for the digestion of vegetable matter. However, it can also cause OPPORTUNISTIC INFECTIONS that result in intra-abdominal SEPSIS; BACTEREMIA; and PERITONITIS.


The phylogenetically newer part of the CORPUS STRIATUM consisting of the CAUDATE NUCLEUS and PUTAMEN. It is often called simply the striatum.


The systematic study of the complete DNA sequences (GENOME) of organisms.


The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)


Centers for acquiring, characterizing, and storing bones or bone tissue for future use.


A genus of DNA viruses in the family PAPILLOMAVIRIDAE causing fibropapillomas in their respective ungulate hosts. Species infected include cattle, European elk, deer, and sheep.


A family of gram-negative bacteria in the order Hydrogenophilales, class BETAPROTEOBACTERIA.


Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs.


A genus of gram-negative, aerobic bacteria in the family OCEANOSPIRILLACEAE. Members of this genus have the ability to synthesize MELANIN pigments.


Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.


Penetration of a PEPTIC ULCER through the wall of DUODENUM or STOMACH allowing the leakage of luminal contents into the PERITONEAL CAVITY.


A medical specialty concerned with maintaining health and providing medical care to children from birth to adolescence.


An abnormal passage within the mouth communicating between two or more anatomical structures.


A technique with which an unknown region of a chromosome can be explored. It is generally used to isolate a locus of interest for which no probe is available but that is known to be linked to a gene which has been identified and cloned. A fragment containing a known gene is selected and used as a probe to identify other overlapping fragments which contain the same gene. The nucleotide sequences of these fragments can then be characterized. This process continues for the length of the chromosome.


ATP-BINDING CASSETTE PROTEINS that are highly conserved and widely expressed in nature. They form an integral part of the ATP-sensitive potassium channel complex which has two intracellular nucleotide folds that bind to sulfonylureas and their analogs.


Contractual arrangement between the lessor (owner) and the lessee in which the use of equipment or facilities is granted to the lessee for a period of time and at a specified rate.


Lower than normal body temperature, especially in warm-blooded animals.


A defense mechanism through which unacceptable impulses and instinctive urges are diverted into personally and socially acceptable channels; e.g., aggression may be diverted through sports activities.


An area in the temporal lobe that is important for memory encoding and retrieval. It is bordered caudally by the parahippocampal cortex (see HIPPOCAMPUS) and ventrally and medially by the ENTORHINAL CORTEX.


Proteins found in any species of protozoan.


The selective extraction of deciduous teeth during the stage of mixed dentition in accordance with the shedding and eruption of the teeth. It is done over an extended period to allow autonomous adjustment to relieve crowding of the dental arches during the eruption of the lateral incisors, canines, and premolars, eventually involving the extraction of the first premolar teeth. (Dorland, 28th ed)


A large supergroup of mostly amoeboid EUKARYOTES whose three main subgroups are CERCOZOA; FORAMINIFERA; and HAPLOSPORIDA. Nearly all of the species possess MITOCHONDRIA and historically many were considered ANIMALS.


An antiviral antibiotic produced by Cephalosporium aphidicola and other fungi. It inhibits the growth of eukaryotic cells and certain animal viruses by selectively inhibiting the cellular replication of DNA polymerase II or the viral-induced DNA polymerases. The drug may be useful for controlling excessive cell proliferation in patients with cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells.


Benzene derivatives that contain a benzyl group with the general formula Phenyl-CH2-R.


The study, based on direct observation, use of statistical records, interviews, or experimental methods, of actual practices or the actual impact of practices or policies.


The large hole at the base of the skull through which the SPINAL CORD passes.


The state of the ATMOSPHERE over minutes to months.


Acquired infection of non-human animals by organisms of the genus TOXOPLASMA.


A variant of well-differentiated epidermoid carcinoma that is most common in the oral cavity, but also occurs in the larynx, nasal cavity, esophagus, penis, anorectal region, vulva, vagina, uterine cervix, and skin, especially on the sole of the foot. Most intraoral cases occur in elderly male abusers of smokeless tobacco. The treatment is surgical resection. Radiotherapy is not indicated, as up to 30% treated with radiation become highly aggressive within six months. (Segen, Dictionary of Modern Medicine, 1992)


A systemic inflammatory response triggered by a variety of factors used in IMMUNOTHERAPY. It is characterized by marked elevations of various inflammatory CYTOKINES and by the following associated conditions: DYSPNEA; FEVER; HEADACHE; HYPOTENSION; NAUSEA; RASH; TACHYCARDIA and/or HYPOXIA.


Extensive collections, reputedly complete, of references and citations to books, articles, publications, etc., generally on a single subject or specialized subject area. Databases can operate through automated files, libraries, or computer disks. The concept should be differentiated from DATABASES, FACTUAL which is used for collections of data and facts apart from bibliographic references to them.


Diagnosis of disease states by recording the spontaneous electrical activity of tissues or organs or by the response to stimulation of electrically excitable tissue.


A plant genus of the family Lecythidaceae. Members contain nasimalun A and B (neo-clerodane diterpenoids).


Inorganic compounds that contain silicon as an integral part of the molecule.


Genes that are introduced into an organism using GENE TRANSFER TECHNIQUES.


Action taken to reduce susceptibility or exposure to health problems and to detect and treat disease in early stages.


A species of protozoa that is a cause of bovine babesiosis. Ticks of the genera Boophilus, Rhipicephalus, and IXODES are the chief vectors.


Works about collections of preserved web pages.


Home Health Agencies
Home Care Agencies
Home Health Care Agencies

Public or private organizations that provide, either directly or through arrangements with other organizations, home health services in the patient's home. (Hospital Administration Terminology, 2d ed)


Resistance to a disease agent resulting from the production of specific antibodies by the host, either after exposure to the disease or after vaccination.


Organic compounds which contain platinum as an integral part of the molecule.


A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.


Nine-carbon deoxyamino SUGAR ACIDS that are substrates for NEURAMINIDASE. Their derivatives include SIALIC ACIDS.


Pads made of various materials used for personal hygiene usually for absorbing URINE or FECES. They can be worn as underpants or pants liners by various age groups, from NEWBORNS to the ELDERLY. Absorbent pads can be made of fluff wood pulp and HYDROGEL absorbent covered with viscose rayon, polyester, polypropylene, or POLYETHYLENE coverstock.


A plant family of the order Geraniales, subclass Rosidae, class Magnoliopsida.


Monitoring of information sources of potential value in detecting an emerging epidemic, whether naturally occurring or the result of bioterrorism.


Angioplasty
Percutaneous Transluminal Angioplasty
Angioplasty, Transluminal
Endoluminal Repair

Reconstruction or repair of a blood vessel, which includes the widening of a pathological narrowing of an artery or vein by the removal of atheromatous plaque material and/or the endothelial lining as well, or by dilatation (BALLOON ANGIOPLASTY) to compress an ATHEROMA. Except for ENDARTERECTOMY, usually these procedures are performed via catheterization as minimally invasive ENDOVASCULAR PROCEDURES.


The reduction or regulation of the population of noxious, destructive, or dangerous insects through chemical, biological, or other means.


Organic chemicals where carbon atoms have been replaced by nitrogen atoms.


A subfamily of lysophospholipid receptors with specificity for lysophosphatidic acid.


Supplies Utilization
Equipment Utilization
Equipment and Supplies Utilization

Extent of use of equipment or supplies. It includes overuse and underuse.


The interrelationship of science and religion.


2 alpha-Cyano-17 beta-hydroxy-4,4',17 alpha-trimethylandrost-5-ene-3-one. An androstenolone-nitrile compound with steroidogenesis-blocking activity.


A family of gram-negative bacteria which are saprophytes, symbionts, or plant pathogens.


A species of gram-negative bacteria causing CONJUNCTIVITIS and KERATOCONJUNCTIVITIS in SHEEP and GOATS.


Fear of or hostility toward Muslims which may be manifested in many ways including acts of violence and legislation against visible aspects of Islam.


Xenopus laevis Proteins
Xenopus Proteins

Proteins obtained from various species of Xenopus. Included here are proteins from the African clawed frog (XENOPUS LAEVIS). Many of these proteins have been the subject of scientific investigations in the area of MORPHOGENESIS and development.


The retention of a denture in place by design, device, or adhesion.


Organic compounds that contain the -NCO radical.


Collaborative approach using active participation of commuit residents in research with a goal of influencing change in community health, systems, programs, or policies.


Surgical formation of an external opening in the sclera, primarily in the treatment of glaucoma.


Apo-Triazo U-33,030 Halcion Trilam Triazolam Gen-Triazolam

A short-acting benzodiazepine used in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. Its use at lower doses with appropriate care and labeling has been reaffirmed by the FDA and most other countries.


Organizations which certify physicians and dentists as specialists in various fields of medical and dental practice.


Promotion and protection of the rights of children; frequently through a legal process.


The presence of DNA from a source foreign to the sample being analysed.


The authorized absence from work of a family member to attend the illness or participate in the care of a parent, a sibling, or other family member. For the care of a parent for a child or for pre- or postnatal leave of a parent, PARENTAL LEAVE is available.


Organic compounds containing the carboxy group (-COOH). This group of compounds includes amino acids and fatty acids. Carboxylic acids can be saturated, unsaturated, or aromatic.


Nonsusceptibility of an organism to the action of penicillins.


A species of gram-negative, facultatively anaerobic, rod-shaped bacteria found in humans and other animals including MAMMALS; BIRDS; REPTILES; and AMPHIBIANS. It has also been isolated from SOIL and WATER as well as from clinical specimens such as URINE; THROAT; SPUTUM; BLOOD; and wound swabs as an opportunistic pathogen.


A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.


Inorganic or organic compounds derived from phosphine (PH3) by the replacement of H atoms. (From Grant & Hackh's Chemical Dictionary, 5th ed)


A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.


A rare, metallic element designated by the symbol, Ga, atomic number 31, and atomic weight 69.72.


Petroselinum
Petroselinum crispum
Parsley

A plant genus of the family APIACEAE used for flavoring food.


A sarcoma characterized by the presence of small cells, cells measuring 9-14 micrometers with a faint or indistinct rim of cytoplasm and an oval-to-elongated nucleus with relatively dense chromatin. (From Segen, Dictionary of Modern Medicine, 1992)


Bicyclic heterocyclic compounds containing a BENZENE ring fused to PYRIDAZINE.


A genus of gram-negative, aerobic, facultatively methylotrophic rods occurring singly or occasionally in rosettes. Members of this genus are usually motile and are isolated from soil, dust, fresh water, lake sediments, leaf surfaces, rice, air, and hospital environments. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


Regulatory proteins that down-regulate phosphorylated G-protein membrane receptors, including rod and cone photoreceptors and adrenergic receptors.


Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.


Transmission of emotions, ideas, and attitudes between individuals in ways other than the spoken language.


The infusion of leaves of CAMELLIA SINENSIS (formerly Thea sinensis) as a beverage, the familiar Asian tea, which contains CATECHIN (especially epigallocatechin gallate) and CAFFEINE.


An endodontic procedure performed to encourage continued physiological development and formation of TOOTH APEX.


The physical environment in which animals are maintained.


The mechanism, in central lymphoid organs (THYMUS; BONE MARROW), that prevents immature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished by CLONAL ANERGY and CLONAL DELETION.


Continuance of life or existence especially under adverse conditions; includes methods and philosophy of survival.


A class of carrier proteins that bind to TRANSFERRIN. Many strains of pathogenic bacteria utilize transferrin-binding proteins to acquire their supply of iron from serum.


A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in the natural environment (soil, water, and plant surfaces) or as an opportunistic human pathogen.


The anterior portion of the developing hindbrain. It gives rise to the CEREBELLUM and the PONS.


The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.


A genus of gram-negative, spiral-shaped bacteria in the family SUCCINIVIBRIONACEAE. It has been isolated from the THROAT and COLON of beagle dogs and from human FECES.


The prevention of access by infecting organisms to the locus of potential infection.


Disorders stemming from the misuse and abuse of alcohol.


Viruses containing two or more pieces of nucleic acid (segmented genome) from different parents. Such viruses are produced in cells coinfected with different strains of a given virus.


Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.


The duct which coveys URINE from the pelvis of the KIDNEY through the URETERS, BLADDER, and URETHRA.


Derivatives of maleimide (the structural formula H2C2(CO)2NH) containing a pyrroledione ring where the hydrogen atom of the NH group is replaced with aliphatic or aromatic groups.


Incentives Expectations Disincentives Motivation

Those factors which cause an organism to behave or act in either a goal-seeking or satisfying manner. They may be influenced by physiological drives or by external stimuli.


The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.


A cancer treatment modality that uses pulsed electrical currents to permeabilize cell membranes (ELECTROPORATION) and thereby enhance the uptake of chemotherapeutic agents into the body's cells.


Literary or artistic items having an erotic theme. It refers especially to books treating sexual love in a sensuous or voluptuous manner. (Webster, 3d ed)


Agents that are put on the SKIN to reduce SWEATING or prevent excess sweating (HYPERHIDROSIS).


Species of gram-negative bacteria in the family ANAPLASMATACEAE, causing EHRLICHIOSIS in DOGS. The most common vector is the brown dog tick. It can also cause disease in humans.


Bryonia dioica
Bryony
Bryonia
Bryonia alba

A plant genus of the family CUCURBITACEAE that is the source of bryodin 1 (a ribosome-inactivating protein).


The interactions between the anterior pituitary and adrenal glands, in which corticotropin (ACTH) stimulates the adrenal cortex and adrenal cortical hormones suppress the production of corticotropin by the anterior pituitary.


Removal of a dead body from the earth after burial.


A plant family of the order Bromeliales, subclass Zingiberidae, class Liliopsida (monocotyledons).


An intermittent and self-limiting headache disorder in individuals with CEREBROSPINAL FLUID SHUNTS emplaced for the treatment of HYDROCEPHALUS. The symptoms of headache, vomiting, and cranial neuropathies are associated with intermittent obstruction of the shunt.


Celestial bodies orbiting around the sun or other stars.


The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.


A species of STIGMATELLA usually isolated from rotting wood. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


A condition of elevated levels of TRIGLYCERIDES in the blood.


The recognition of professional or technical competence through registration, certification, licensure, admission to association membership, the award of a diploma or degree, etc.


The oily substance secreted by SEBACEOUS GLANDS. It is composed of KERATIN, fat, and cellular debris.


Radiography of the bronchial tree after injection of a contrast medium.


Atropinol
Atropine Sulfate
Atropine Sulfate Anhydrous
AtroPen
Atropine
Atropin Augenöl

An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.


The portion of chromosome material that remains condensed and is transcriptionally inactive during INTERPHASE.


Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.


Vertical Dimension
Mandibular Rest Position
Rest Vertical Dimension
Vertical Dimension of Occlusion
Vertical Dimension at Rest

The length of the face determined by the distance of separation of jaws. Occlusal vertical dimension (OVD or VDO) or contact vertical dimension is the lower face height with the teeth in centric occlusion. Rest vertical dimension (VDR) is the lower face height measured from a chin point to a point just below the nose, with the mandible in rest position. (From Jablonski, Dictionary of Dentistry, 1992, p250)


Prosthesis Durability
Prosthesis Failure
Prosthesis Migration
Prosthesis Survival
Prosthesis Loosening

Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.


Fungus infection of the external ear, usually by ASPERGILLUS species


Form of granulomatous uveitis occurring in the region of the pars plana. This disorder is a common condition with no detectable focal pathology. It causes fibrovascular proliferation at the inferior ora serrata.


Where most of the stratospheric ozone is concentrated, in the lower stratosphere, between 9-18 miles above the Earth's surface.


The presence of free HEMOGLOBIN in the URINE, indicating hemolysis of ERYTHROCYTES within the vascular system. After saturating the hemoglobin-binding proteins (HAPTOGLOBINS), free hemoglobin begins to appear in the urine.


An obsolete superorder of flightless birds consisting of four orders: the Apterygiformes, which includes Kiwi birds; the Casuariiformes, the RHEIFORMES or Rheas, and the STRUTHIONIFORMES, or ostriches.


DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. Leucines occurring in heptad repeats end up on the same sides of the helixes and are adjacent to each other in the stem of the Y (the "zipper" region). The DNA-binding residues are located in the bifurcated region of the Y.


Precursor cells destined to differentiate into cardiac myocytes (MYOCYTES, CARDIAC).


Heterocyclic acids that are derivatives of 4-pyridinecarboxylic acid (isonicotinic acid).


Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.


Abnormal structures located in various parts of the brain and composed of dense arrays of paired helical filaments (neurofilaments and microtubules). These double helical stacks of transverse subunits are twisted into left-handed ribbon-like filaments that likely incorporate the following proteins: (1) the intermediate filaments: medium- and high-molecular-weight neurofilaments; (2) the microtubule-associated proteins map-2 and tau; (3) actin; and (4) UBIQUITINS. As one of the hallmarks of ALZHEIMER DISEASE, the neurofibrillary tangles eventually occupy the whole of the cytoplasm in certain classes of cell in the neocortex, hippocampus, brain stem, and diencephalon. The number of these tangles, as seen in post mortem histology, correlates with the degree of dementia during life. Some studies suggest that tangle antigens leak into the systemic circulation both in the course of normal aging and in cases of Alzheimer disease.


A group of abnormal hemoglobins with similar electrophoretic characteristics. They have faster electrophoretic mobility and different amino acid substitutions in either the alpha or beta chains than normal adult hemoglobin. Some of the variants produce hematologic abnormalities, others result in no clinical disorders.


An order of anaerobic methanogens in the kingdom EURYARCHAEOTA. They are pseudosarcina, coccoid or sheathed rod-shaped and catabolize methyl groups. The cell wall is composed of protein. The order includes one family, METHANOCOCCACEAE. (From Bergey's Manual of Systemic Bacteriology, 1989)


The walnut plant family of the order Juglandales, subclass Hamamelidae, class Magnoliopsida. They are mainly temperate zone trees.


Long-term care facilities which provide supervision and assistance in activities of daily living with medical and nursing services when required.


A benign brain tumor composed of neural elements which most often arise from the SEPTUM PELLUCIDUM and the walls of the lateral ventricles. Immunohistochemistry and electron microscopy evaluations may reveal expression of neuron specific enolase and synaptophysin and cells containing microtubuli, neurosecretory granules, and presynaptic vesicles. (From Acta Med Port 1994 Feb;7(2):113-9)


A process in which offspring possessing desired genetic traits are produced.


MOVEMENT across different GEOGRAPHIC LOCATIONS.


Pumpkins
Cucurbita
Squash Plant
Squashes

A plant genus of the family CUCURBITACEAE, order Violales, subclass Dilleniidae, which includes pumpkin, gourd and squash.


Red blood cell precursors, corresponding to ERYTHROBLASTS, that are larger than normal, usually resulting from a FOLIC ACID DEFICIENCY or VITAMIN B 12 DEFICIENCY.


The conscious portion of the personality structure which serves to mediate between the demands of the primitive instinctual drives, (the id), of internalized parental and social prohibitions or the conscience, (the superego), and of reality.


Amino acids and chains of amino acids connected by peptide linkages.


CHOLESTANES substituted with any number of keto groups.


Therapeutic cult concerned with intangible energies surrounding the living body and based on the detection of these intrinsic radiations by dowsing, or divining, or the use of more elaborate instruments (radionics).


Standardized objective tests designed to facilitate the evaluation of personality.


Stannous Pyrophosphates
Tin Polyphosphates
Tin Pyrophosphates
Stannous Polyphosphates

Poly or pyrophosphates of tin. In conjunction with radioactive technetium these compounds are used as bone-scanning agents and in scintigraphy to diagnose myocardial and cerebral infarction.


A genus in the family CIRCOVIRIDAE comprising the single species CHICKEN ANEMIA VIRUS.


Kale
Brassica
Cauliflower
Collard Green
Cabbage
Brussel Sprout
Broccoli

A plant genus of the family Cruciferae. It contains many species and cultivars used as food including cabbage, cauliflower, broccoli, Brussel sprouts, kale, collard greens, MUSTARD PLANT; (B. alba, B. junica, and B. nigra), turnips (BRASSICA NAPUS) and rapeseed (BRASSICA RAPA).


A genus of SPONGES in the family Petrosiidae, characterized by an ectosomal skeleton consisting only of an isotropic reticulation of single spicules or spicule tracts.


AY-23,028
Butaclamol Hydrochloride
Butaclamol

A benzocycloheptapyridoisoquinolinol that has been used as an antipsychotic, especially in schizophrenia.


Gram-negative bacteria occurring in the lower intestinal tracts of man and other animals. It is the most common species of anaerobic bacteria isolated from human soft tissue infections.


A plant family of the order Sapindales, subclass Rosidae, class Magnoliopsida. Leaves are opposite and usually toothed or lobed. The fruit, a samara (a winged nutlet), splits into two (rarely three) winged, one-seeded parts. This family is widely distributed in the Northern Hemisphere.


Qualified medical professionals who specialize in treating NERVOUS SYSTEM DISEASES.


A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).


Primaquine Phosphate
Primaquine Diphosphate
Primaquine
Primacin

An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)


A free-living soil amoeba pathogenic to humans and animals. It occurs also in water and sewage. The most commonly found species in man is NAEGLERIA FOWLERI which is the pathogen for primary amebic meningoencephalitis in primates.


A genus of VIBRIONACEAE, made up of short, slightly curved, motile, gram-negative rods. Various species produce cholera and other gastrointestinal disorders as well as abortion in sheep and cattle.


Procedures for measuring a response to odorants.


A genus of herbaceous plants with asymmetrically-shaped flowers and finely divided leaves, native to east Asia and North America.


A benign neoplasm composed of glandular and fibrous tissues, with a relatively large proportion of glands. (Stedman, 25th ed)


The upper chamber of the COCHLEA that is filled with PERILYMPH. It is connected to SCALA TYMPANI via helicotrema at the apex of the cochlea.


Asymmetries in the topography and refractive index of the corneal surface that affect visual acuity.


A genus of SPONGES in the family Axinellidae, comprised of a choanosomal skeleton differentiated in the axial and extra-axial region. The type species is Axinella polypoides.


A genus of asporogenous bacteria that is widely distributed in nature. Its organisms appear as straight to slightly curved rods and are known to be human and animal parasites and pathogens.


Tests for central hearing disorders based on the competing message technique (binaural separation).


A plant genus of the family CELASTRACEAE.


Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.


The measurement of various aspects of MAGNETIC FIELDS.


A class of enzymes that catalyze geometric or structural changes within a molecule to form a single product. The reactions do not involve a net change in the concentrations of compounds other than the substrate and the product.(from Dorland, 28th ed) EC 5.


Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.


A condition marked by the development of widespread xanthomas, yellow tumor-like structures filled with lipid deposits. Xanthomas can be found in a variety of tissues including the SKIN; TENDONS; joints of KNEES and ELBOWS. Xanthomatosis is associated with disturbance of LIPID METABOLISM and formation of FOAM CELLS.


Groups that serve as a standard for comparison in experimental studies. They are similar in relevant characteristics to the experimental group but do not receive the experimental intervention.


Plant hormones that promote the separation of daughter cells after mitotic division of a parent cell. Frequently they are purine derivatives.


A family of BONE MORPHOGENETIC PROTEIN-related proteins that are primarily involved in regulation of CELL DIFFERENTIATION.


Infection with flukes of the genus Dicrocoelium.


Thinly cut sections of frozen tissue specimens prepared with a cryostat or freezing microtome.


The branch of medicine concerned with the physiological and pathological aspects of the aged, including the clinical problems of senescence and senility.


A microcomputer-based software package providing a user-friendly interface to the MEDLARS system of the National Library of Medicine.


Initial drug treatment designed to bring about REMISSION INDUCTION. It is typically a short-term and high-dose drug treatment that is followed by CONSOLIDATION CHEMOTHERAPY and then MAINTENANCE CHEMOTHERAPY.


Usually organized community efforts to raise money to promote financial programs of institutions. The funds may include individual gifts.


A genus of gram-positive, asporogenous, lactic acid bacteria, in the family LEUCONOSTOCACEAE.


A drug-metabolizing, cytochrome P-450 enzyme which catalyzes the hydroxylation of aniline to hydroxyaniline in the presence of reduced flavoprotein and molecular oxygen. EC 1.14.14.-.


Insertion of an endosseous implant with a narrow wedge-shaped infrastructure extending through the oral mucosa into the mouth and bearing openings or vents through which tissue grows to obtain retention.


Disorders characterized by abnormal proliferation of primary cells of the immune system or by excessive production of immunoglobulins.


An element of the rare earth family of metals. It has the atomic symbol Tb, atomic number 65, and atomic weight 158.92.


Tandem Affinity Chromatography
Tandem Affinity Purification

A technique used to isolate specific interacting partners of MACROMOLECULAR COMPLEXES that have been assembled with a tagged component (bait) that interacts with other partners in the complex. The interacting bait component is labeled with a dual-affinity tag that allows for capture of the complex by IMMUNOPRECIPITATION, followed by purification of only the partners of the complex interacting with the bait by affinity chromatography.


The type species of the genus BARTONELLA, a gram-negative bacteria found in humans. It is found in the mountain valleys of Peru, Ecuador, and Southwest Columbia where the sandfly (see PHLEBOTOMUS) vector is present. It causes OROYA FEVER and VERRUGA PERUANA.


An antihyperlipoproteinemic agent and uricosuric agent.


The form of energy and the sensation of an increase in temperature. Its interest in medicine is largely with reference to its physiological effects, its therapeutic use, and its use in procedures in physics and physical chemistry.


An emotionally painful, shocking, stressful, and sometimes life-threatening experience. It can result from witnessing distressing events such as natural disasters, physical or sexual abuse, and terrorism or other acts of violence. (https://www.nimh.nih.gov/health/)


Several groups of nuclei in the thalamus that serve as the major relay centers for sensory impulses in the brain.


An alloy of 60% cobalt, 20% chromium, 5% molybdenum, and traces of other substances. It is used in dentures, certain surgical appliances, prostheses, implants, and instruments.


The sites in a dividing cell where the minus ends of the spindle MICROTUBULES assemble and where the separated sister CHROMATIDS converge.


The condition of being heterozygous for hemoglobin S.


Extensions of the nerve cell body. They are short and branched and receive stimuli from other NEURONS.


Techniques using a laser to cut away and harvest a specific cell or cluster of cells from a tissue section while viewing it under the microscope.


Interventions to provide care prior to, during, and immediately after surgery.


Linear polymers in which orthophosphate residues are linked with energy-rich phosphoanhydride bonds. They are found in plants, animals, and microorganisms.


The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.


Medication Systems
Unit Dose Drug Distribution Systems

Overall systems, traditional or automated, to provide medication to patients.


The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.


An enzyme bound to the inner mitochondrial membrane that catalyzes the oxidation of CHOLINE to BETAINE.


A genus of the MYXOCOCCALES having vegetative cells which are straight rods with tapered ends and myxospores which are short and somewhat crooked. Fruiting bodies consist of spherical, ovoid, or club-shaped sporangioles on stalks. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


A plant genus of the family Plantaginaceae. Members contain thyrsiflorin and other scopadulane (labdane) type DITERPENES.


An enzyme (AAA ATPase) consisting of the 60 kDa ATPase subunit (p60 subunit A1) which severs MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets the enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES to allow depolymerization and poleward motion of chromosomes. It is also a regulator of microtubule dynamics in NEURONAL OUTGROWTH.


HLA-DR antigen subtypes that have been classified according to their affinity to specific ANTIBODIES. The DNA sequence analyses of HLA-DR ALPHA-CHAINS and HLA-DR BETA-CHAINS has for the most part revealed the specific alleles that are responsible for each serological subtype.


A species in the genus ANABAENA containing gas vacuoles that gives buoyancy to the organism. It can form extensive blooms in FRESH WATER and is responsible for acute poisonings of various animals.


The branch of pharmacology dealing especially with the action of drugs upon various parts of the nervous system.


Inflammation of the lacrimal sac. (Dorland, 27th ed)


A genus of bacteria found in the human genital and urinary tract. It is considered to be a major cause of bacterial vaginosis (VAGINOSIS, BACTERIAL).


An approach to nutrition based on whole cereal grains, beans, cooked vegetables and the Chinese YIN-YANG principle. It advocates a diet consisting of organic and locally grown foods, seasonal vegetables, complex carbohydrates, and fewer fats, sugars, and chemically processed foods.


Rendering pathogens harmless through the use of heat, antiseptics, antibacterial agents, etc.


Isovinculin beta-Vinculin Vinculin alpha-Vinculin

A cytoskeletal protein associated with cell-cell and cell-matrix interactions. The amino acid sequence of human vinculin has been determined. The protein consists of 1066 amino acid residues and its gene has been assigned to chromosome 10.


A malformation that is characterized by a muscle bridge over a segment of the CORONARY ARTERIES. Systolic contractions of the muscle bridge can lead to narrowing of coronary artery; coronary compression; MYOCARDIAL ISCHEMIA; MYOCARDIAL INFARCTION; and SUDDEN CARDIAC DEATH.


A group of enzymes that catalyze the hydrolysis of diphosphate bonds in compounds such as nucleoside di- and tri-phosphates, and sulfonyl-containing anhydrides such as adenylylsulfate. (Enzyme Nomenclature, 1992) EC 3.6.


The hairs which project from the edges of the EYELIDS.


An infant born at or after 42 weeks of gestation.


A specialized residential treatment program for behavior disorders including substance abuse. It may include therapeutically planned group living and learning situations including teaching of adaptive skills to help patient functioning in the community. (From Kahn, A. P. and Fawcett, J. Encyclopedia of Mental Health, 1993, p320.)


Facilities that convert NUCLEAR ENERGY into electrical energy.


The activities and endeavors of the public health services in a community on any level.


A family of gram-negative, aerobic bacteria in the order Pseudomonadales. Some strains are parasites of the mucosal membranes of animals and humans; others are found in association with food products or in the environment.


A genus of gram-positive bacteria in the family Thermoactinomycetaceae, that can cause FARMER'S LUNG.


Nerve cells of the RETINA in the pathway of transmitting light signals to the CENTRAL NERVOUS SYSTEM. They include the outer layer of PHOTORECEPTOR CELLS, the intermediate layer of RETINAL BIPOLAR CELLS and AMACRINE CELLS, and the internal layer of RETINAL GANGLION CELLS.


Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.


Activities or games, usually involving physical effort or skill. Reasons for engagement in sports include pleasure, competition, and/or financial reward.


State Health Plans
Comprehensive Health Plans, State

State plans prepared by the State Health Planning and Development Agencies which are made up from plans submitted by the Health Systems Agencies and subject to review and revision by the Statewide Health Coordinating Council.


Community
Place of Birth
Residential Selection
Neighborhood
Domicile
Living Arrangements
Residence Characteristics

Elements of residence that characterize a population. They are applicable in determining need for and utilization of health services.


A reaction characterized by a violet color upon the addition of copper sulfate to all compounds with two amide or peptide bonds linked directly or through an intermediate carbon atom. Used in the detection and estimation of proteins and peptides having more than two amino acids.


A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)


Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.


Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)


Four-legged hoofed mammals that are closely related to giraffes, although they bear stripes similar to zebras.


Polysaccharide isolated from the edible mushroom LENTINULA EDODES. The exact composition is unknown.


Marijuana Use
Recreational Marijuana Use
Marijuana-Related Disorder

Medicinal or recreational utilization of MARIJUANA.


A family of anaerobic METHANOCOCCALES whose organisms are thermophilic methanogens that produce methane from hydrogen and simple carbon sources such as carbon dioxide.


The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)


LIPOLYSIS of stored LIPIDS in the ADIPOSE TISSUE to release FREE FATTY ACIDS. Mobilization of stored lipids is under the regulation of lipolytic signals (CATECHOLAMINES) or anti-lipolytic signals (INSULIN) via their actions on the hormone-sensitive LIPASE. This concept does not include lipid transport.


Bacterial variants, unable to form a complete cell wall, which are formed in cultures by various bacteria; granules (L bodies) appear, unite, and grow into amorphous bodies which multiply and give rise to bacterial cells morphologically indistinguishable from the parent strain.


Peculiarities associated with the internal structure, form, topology, or architecture of organisms that distinguishes them from others of the same species or group.


Coagulant substances inhibiting the anticoagulant action of heparin.


A genus of gram-negative, rod-shaped bacteria that is widely distributed in TICKS and various mammals throughout the world. Infection with this genus is particularly prevalent in CATTLE; SHEEP; and GOATS.


A mitosporic Hypocreales fungal genus, various species of which are important parasitic pathogens of plants and a variety of vertebrates. Teleomorphs include GIBBERELLA.


The application of nutritional principles to regulation of the diet and feeding persons or groups of persons.


Muscular rigidity which develops in the cadaver usually from 4 to 10 hours after death and lasts 3 or 4 days.


A condition characterized by the dilated tortuous veins of the SPERMATIC CORD with a marked left-sided predominance. Adverse effect on male fertility occurs when varicocele leads to an increased scrotal (and testicular) temperature and reduced testicular volume.


A filarial parasite primarily affecting dogs and cats, but causing an emerging zoonosis in humans involving subcutaneous lesions. It is transmitted by MOSQUITOES.


COSMETICS that are associated with therapeutic effects.


Complex compounds where two cyclic molecules are interlaced together as links in a chain. They have potential use in NANOTECHNOLOGY.


A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.


Porphyrins with four methyl and four ethyl side chains attached to the pyrrole rings.


A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.


Macrophage Inflammatory Proteins
Macrophage Inflammatory Protein-1

Heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of MACROPHAGES, these chemokines are produced by a variety of cell types including NEUTROPHILS; FIBROBLASTS; and EPITHELIAL CELLS. They likely play a significant role in respiratory tract defenses.


Pain-alleviating drugs characterized by rapid action time.


A medical-surgical specialty concerned with the physiology and disorders primarily of the female genital tract, as well as female endocrinology and reproductive physiology.


A genus of lichen-forming fungi containing usnic acid and mucilage. Usnea barbata is used in HERBAL MEDICINE.


Fever accompanied by a significant reduction in the number of NEUTROPHILS.


A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.


Slow-moving exclusively arboreal mammals that inhabit the tropical forests of South and Central America.


The circulation of the BLOOD through the MICROVASCULAR NETWORK.


Aniline compounds that contain two amino groups. They are used as a precursor in the synthesis of HETEROCYCLIC COMPOUNDS and POLYMERS. p-Phenylenediamine is used in the manufacture of HAIR DYES and is an ALLERGEN.


A species of gram-negative bacteria, in the family Aeromonadaceae. It is strictly parasitic and often pathogenic causing FURUNCULOSIS in SALMONIDS and ulcer disease in GOLDFISH.


Physician Assignment Acceptance
Medicare Assignment

Concept referring to the standardized fees for services rendered by health care providers, e.g., laboratories and physicians, and reimbursement for those services under Medicare Part B. It includes acceptance by the physician.


A measure of a patient's ability to break down lactose.


A family of DNA viruses infecting plants and transmitted by APHIDS. Genera include NANOVIRUS and BABUVIRUS.


A plant genus of the family PEDALIACEAE that is the source of the edible seed and SESAME OIL.


The vapor state of matter; nonelastic fluids in which the molecules are in free movement and their mean positions far apart. Gases tend to expand indefinitely, to diffuse and mix readily with other gases, to have definite relations of volume, temperature, and pressure, and to condense or liquefy at low temperatures or under sufficient pressure. (Grant & Hackh's Chemical Dictionary, 5th ed)


A group of 13 or more ribonucleotides in which the phosphate residues of each ribonucleotide act as bridges in forming diester linkages between the ribose moieties.


The use of faith and spirit to cure disease.


Sweat-producing structures that are embedded in the DERMIS. Each gland consists of a single tube, a coiled body, and a superficial duct.


Procollagen
Procollagen Type M
Protocollagen

A precursor of procollagen consisting of procollagen peptide chains in which proline and lysine have not yet been hydroxylated.


A nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more specific drugs.


Segond Fracture
Tibial Fractures
Tillaux Fracture
Toddler's Fracture


Constructions built to access underground water which will rise to the surface under hydrostatic pressure.


Nucleus in the NEOSTRIATUM of bird brains that sends signals for song production and receives auditory input. In some adult SONGBIRDS, research has shown that the size of this nucleus changes seasonally and that it exhibits neurogenesis.


New abnormal growth of tissue in the FACE.


A plant genus of the family SOLANACEAE. Members contain TROPANES. The common name of trumpet flower is also sometimes used for GELSEMIUM.


The smallest divisions of the arteries located between the muscular arteries and the capillaries.


A greasy substance with a smoky odor and burned taste created by high temperature treatment of BEECH and other WOOD; COAL TAR; or resin of the CREOSOTE BUSH. It contains CRESOLS and POLYCYCLIC AROMATIC HYDROCARBONS which are CARCINOGENS. It has been widely used as wood preservative and in PESTICIDES and had former use medicinally in DISINFECTANTS; LAXATIVES; and DERMATOLOGIC AGENTS.


Peptides composed of between two and twelve amino acids.


Coordination of coverage eligibility of those individuals who are entitled to MEDICAID and MEDICARE.


A method of providing future reproductive opportunities before a medical treatment with known risk of loss of fertility. Typically reproductive organs or tissues (e.g., sperm, egg, embryos and ovarian or testicular tissues) are cryopreserved for future use before the medical treatment (e.g., chemotherapy, radiation) begins.


A plant genus of the family COMBRETACEAE. Triterpenes and combretastatin have been identified in members of this genus.


The internal portion of the kidney, consisting of striated conical masses, the renal pyramids, whose bases are adjacent to the cortex and whose apices form prominent papillae projecting into the lumen of the minor calyces.


Qualified professionals trained in primary eye and vision care, including measurement of visual abilities, diagnosing disorders of the visual system and provision of treatment such as prescriptions for correction of visual defects with lenses or glasses and vision therapy.


A species of gram-positive bacteria in the family Clostridiaceae responsible for spoilage of some CHEESE via FERMENTATION of BUTYRIC ACID.


Fatty acids which are unsaturated in only one position.


A genus of ascomycetous mold in the family Trichocomaceae, order EUROTIALES. Byssochlamys species are responsible for spoilage and degradation of fruit and fruit juices. Anamorphs are found in the genus PAECILOMYCES.


The physical characteristics of the body, including the mode of performance of functions, the activity of metabolic processes, the manner and degree of reactions to stimuli, and power of resistance to the attack of pathogenic organisms.


A species of gram-negative, aerobic, rod-shaped bacteria found in hot springs of neutral to alkaline pH, as well as in hot-water heaters.


A blood-filled VAGINA that is obstructed.


A gram-positive organism found in dental plaque, in blood, on heart valves in subacute endocarditis, and infrequently in saliva and throat specimens. L-forms are associated with recurrent aphthous stomatitis.


Reactions of an individual or groups of individuals with relation to the immediate surrounding area including the animate or inanimate objects within that area.


Modernization
Social Impact
Social Development
Social Change

A shift, alteration, modification, or evolution of human behavior and culture, which over time, results in measurable consequences on societal values and norms.


Its major components are NASAL BONES; NASAL CARTILAGES; and NASAL SEPTUM.


Type of vision test used to determine COLOR VISION DEFECTS.


A synthetic steroid with progestational and contraceptive activities.


Domesticated farm animals raised for home use or profit but excluding POULTRY. Typically livestock includes CATTLE; SHEEP; HORSES; SWINE; GOATS; and others.


VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.


A theoretical psychoanalytical system centered around symbols of the unconscious with the unconscious material derived from two sources - the personal unconscious (repressed or forgotten experiences, thoughts and feelings) and the collective or objective unconscious (the universal inherited qualities which dispose individuals to behave in ways similar to their ancestors).


A genus of the family HERPESVIRIDAE, subfamily GAMMAHERPESVIRINAE, infecting B-cells in humans and new world primates. The type species human herpesvirus 4 (HERPESVIRUS 4, HUMAN) is better known as the Epstein-Barr virus.


Reactions to an event or set of events which are considered to be of pathological degree, that have not developed into a neurosis, psychosis, or personality disorder with fixed patterns.


A salt of lithium that has been used experimentally as an immunomodulator.


Postcoital contraceptives which owe their effectiveness to hormonal preparations.


A genus of STARFISH in the family Asterinidae. They externally hold developing embryos (EMBRYO, NON-MAMMALIAN) among the spines below the oral surface.


A positive-stranded RNA virus species in the genus HEPEVIRUS, causing enterically-transmitted non-A, non-B hepatitis (HEPATITIS E).


Pneumonia due to aspiration or inhalation of various oily or fatty substances.


Dermatologic disorders attendant upon non-dermatologic disease or injury.


Quantitative Trait Loci
Quantitative Trait Loci Genes

Genetic loci associated with a quantitative trait.


A family of RNA viruses infecting a broad range of animals. Most individual species are restricted to their natural hosts. They possess a characteristic six-pointed starlike shape whose surfaces have cup-shaped (chalice) indentions. Transmission is by contaminated food, water, fomites, and occasionally aerosolization of secretions. Genera include LAGOVIRUS; NORWALK-LIKE VIRUSES; SAPPORO-LIKE VIRUSES; and VESIVIRUS.


Infection in cattle caused by various species of trypanosomes.


Synthesized magnetic particles under 100 nanometers possessing many biomedical applications including DRUG DELIVERY SYSTEMS and CONTRAST AGENTS. The particles are usually coated with a variety of polymeric compounds.


Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).


A small, circumscribed, benign tumor of the genital tract, composed of small glandlike spaces lined by flattened or cuboidal mesothelium-like cells. (From Dorland, 27th ed)


A species of THIOCAPSA which is facultatively aerobic and chemotrophic and which can utilize thiosulfate. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.


Inorganic compounds that contain aluminum as an integral part of the molecule.


Heterocyclic compounds of a ring with SULFUR and two NITROGEN atoms fused to a BENZENE ring. Members inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS and are used as DIURETICS.


A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.


Instruments inserted into the vagina for examination of the tissues of the vagina and cervix by means of a magnifying lens.


Panokase Viokase Pancrelipase Ku-Zyme Pancrease Cotazym-S Creon Pancron Ilozyme Pancrecarb Zymase Cotazyme Lipram Pertzye Protilase Ultrase Encron

A preparation of hog pancreatic enzymes standardized for lipase content.


Pathological processes of the VESTIBULAR LABYRINTH which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls.


Large herbivorous tropical American lizards.


Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed)


A tri-hydroxy cyclohexene carboxylic acid important in biosynthesis of so many compounds that the shikimate pathway is named after it.


The flexible rope-like structure that connects a developing FETUS to the PLACENTA in mammals. The cord contains blood vessels which carry oxygen and nutrients from the mother to the fetus and waste products away from the fetus.


A cloprostenol-derived amide that is used as an ANTIHYPERTENSIVE AGENT in the treatment of OPEN-ANGLE GLAUCOMA and OCULAR HYPERTENSION.


Works about books, articles or other publications on herbs or plants describing their medicinal value.


A genus of gram-negative, aerobic, nonsporeforming rods which usually contain granules of poly-beta-hydroxybutyrate. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


Family of gram-negative bacteria that occur in leaf nodules and the rhizosphere of higher plants.


A plastic substance deposited by insects or obtained from plants. Waxes are esters of various fatty acids with higher, usually monohydric alcohols. The wax of pharmacy is principally yellow wax (beeswax), the material of which honeycomb is made. It consists chiefly of cerotic acid and myricin and is used in making ointments, cerates, etc. (Dorland, 27th ed)


A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's).


Curved bacteria, usually crescent-shaped rods, with ends often tapered, occurring singly, in pairs, or short chains. They are non-encapsulated, non-sporing, motile, and ferment glucose. Selenomonas are found mainly in the human buccal cavity, the rumen of herbivores, and the cecum of pigs and several rodents. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


A standard and widely accepted diagnostic test used to identify patients who have a vasodepressive and/or cardioinhibitory response as a cause of syncope. (From Braunwald, Heart Disease, 7th ed)


The eight bones of the wrist: SCAPHOID BONE; LUNATE BONE; TRIQUETRUM BONE; PISIFORM BONE; TRAPEZIUM BONE; TRAPEZOID BONE; CAPITATE BONE; and HAMATE BONE.


Prepulse Inhibition
Prepulse Facilitation

A neurophysiological phenomenon in which the response to a startling stimulus (pulse) is decreased when a weaker prestimulus (prepulse) precedes it closely in time. It is used as an operational measure of sensorimotor gating.


Stable gold atoms that have the same atomic number as the element gold, but differ in atomic weight. Au-197 is a stable isotope.


A species of MORBILLIVIRUS causing a severe, often fatal enteritis and pneumonia (PESTE-DES-PETITS-RUMINANTS) in sheep and goats.


A plant genus of the family POACEAE. The EDIBLE GRAIN, barley, is widely used as food.


Flammable, amorphous, vegetable products of secretion or disintegration, usually formed in special cavities of plants. They are generally insoluble in water and soluble in alcohol, carbon tetrachloride, ether, or volatile oils. They are fusible and have a conchoidal fracture. They are the oxidation or polymerization products of the terpenes, and are mixtures of aromatic acids and esters. Most are soft and sticky, but harden after exposure to cold. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)


Apparatus that provides mechanical circulatory support during open-heart surgery, by passing the heart to facilitate surgery on the organ. The basic function of the machine is to oxygenate the body's venous supply of blood and then pump it back into the arterial system. The machine also provides intracardiac suction, filtration, and temperature control. Some of the more important components of these machines include pumps, oxygenators, temperature regulators, and filters. (UMDNS, 1999)


A suborder of ciliate protozoa having a body that is commonly oval to elliptical in shape. Most species are free-living in widely diverse habitats.


Enzymes that catalyze the transfer of an aminoacyl group from donor to acceptor resulting in the formation of an ester or amide linkage. EC 2.3.2.


The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine.


4-Hydroxy-4H-furo(3,2-c)pyran-2(6H)-one. A mycotoxin produced by several species of Aspergillus and Penicillium. It is found in unfermented apple and grape juice and field crops. It has antibiotic properties and has been shown to be carcinogenic and mutagenic and causes chromosome damage in biological systems.


Expert Witness
Expert Testimony
Expert Opinion

Presentation of pertinent data by one with special skill or knowledge representing mastery of a particular subject.


A genus of aquatic newts belonging to the family Salamandridae and sometimes referred to as "spiny" tritons. There are two species P. waltlii and P. poireti. P. waltlii is commonly used in the laboratory. Since this genus adapts to aquarium living, it is easy to maintain in laboratories.


A family of 3,6-di(substituted-amino)-9-benzoate derivatives of xanthene that are used as dyes and as indicators for various metals; also used as fluorescent tracers in histochemistry.


Hardening of the KIDNEY due to infiltration by fibrous connective tissue (FIBROSIS), usually caused by renovascular diseases or chronic HYPERTENSION. Nephrosclerosis leads to renal ISCHEMIA.


A genus of nematode worms in the superfamily Heterakoidea. A. galli and A. lineata are important intestinal parasites of domestic fowl.


The complete failure of gonadal development.


The act of deceiving or the fact of being deceived.


A defense mechanism, operating unconsciously, whereby that which is emotionally unacceptable in the self is rejected and attributed (projected) to others.


Blood Pressure
Diastolic Pressure
Systolic Pressure
Pulse Pressure

Difference between systolic and diastolic pressures.


Positively charged atoms, radicals or group of atoms with a valence of plus 1, which travel to the cathode or negative pole during electrolysis.


A plant genus of the family Salicaceae that is the source of RYANODINE.


Branch Retinal Artery Occlusion
Retinal Artery Occlusion
Central Retinal Artery Occlusion

Sudden ISCHEMIA in the RETINA due to blocked blood flow through the CENTRAL RETINAL ARTERY or its branches leading to sudden complete or partial loss of vision, respectively, in the eye.


A partitioning within cells due to the selectively permeable membranes which enclose each of the separate parts, e.g., mitochondria, lysosomes, etc.


A syndrome characterized by HYPERPIGMENTATION, enlarging pituitary mass, visual defects secondary to compression of the OPTIC CHIASM, and elevated serum ACTH. It is caused by the expansion of an underlying ACTH-SECRETING PITUITARY ADENOMA that grows in the absence of feedback inhibition by adrenal CORTICOSTEROIDS, usually after ADRENALECTOMY.


Periphlebitis is inflammation of the outer coat of a vein or of tissues surrounding the vein.


A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406)


Reducing a dead body to ashes by burning or incineration.


A species of gram-negative to gram-variable, nitrogen-fixing bacteria. They are free-living in SOIL or found in association with PLANT ROOTS. It is the type species of the genus AZOSPIRILLUM.


A plant genus of the family ASTERACEAE. Members contain galegine (GUANIDINES).


A bone on the ventral side of the shoulder girdle, which in humans is commonly called the collar bone.


Ever Married
Currently Married
Marital Conflict
Interparental Conflict
Family Conflict

Struggle or disagreement between parents, parent and child or other members of a family.


Infection with parasitic protozoa of the genus CYCLOSPORA. It is distributed globally and causes a diarrheal illness. Transmission is waterborne.


Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.


A demographic parameter indicating a person's status with respect to marriage, divorce, widowhood, singleness, etc.


The quality of surface form or outline of CELLS.


A genus in the family FELIDAE comprising felines with long legs, ear tufts, and a short tail.


A suborder of protozoa characterized by peniculi, which are often situated deep in the buccal cavity, and by fusiform trichocysts.


A platelet-specific protein which is released when platelets aggregate. Elevated plasma levels have been reported after deep venous thrombosis, pre-eclampsia, myocardial infarction with mural thrombosis, and myeloproliferative disorders. Measurement of beta-thromboglobulin in biological fluids by radioimmunoassay is used for the diagnosis and assessment of progress of thromboembolic disorders.


A subtype of thioredoxin reductase found primarily in the CYTOSOL.


Scholarly Communication
Scholarly Publishing

System through which research and other scholarly writings are created, evaluated for quality, disseminated to the scholarly community, and preserved for future use. It includes both formal means of communication, such as publication in peer-reviewed journals, and informal channels, such as electronic listservs. (from Association of College & Research Libraries, “Principles and Strategies for the Reform of Scholarly Communication 1,” 2003)


Surface resistance to the relative motion of one body against the rubbing, sliding, rolling, or flowing of another with which it is in contact.


A plant family of the order Cornales, subclass Rosidae, class Magnoliopsida that is a loose grouping of woody ornamentals: 11 of its 14 genera have been placed in single families by some authorities. Some botanists combine members of NYSSACEAE into this family.


Dissent
Political Dissent
Disputes
Professional-Patient Disagreement
Professional-Family Disagreement
Dissent and Disputes

Differences of opinion or disagreements that may arise, for example, between health professionals and patients or their families, or against a political regime.


The detection of long and short term side effects of conventional and traditional medicines through research, data mining, monitoring, and evaluation of healthcare information obtained from healthcare providers and patients.


A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.


Substances or organisms which pollute the water or bodies of water. Use for water pollutants in general or those for which there is no specific heading.


A genus of the family BUNYAVIRIDAE named after NAIROBI SHEEP DISEASE, an acute, hemorrhagic, tick-borne, gastroenteritis affecting sheep and goats. The type species is Dugbe virus. Some viruses in this genus are capable of causing severe and fatal disease in humans.


A genus of gram-negative bacteria in the family ACIDAMINOCOCCACEAE, found in the RUMEN of SHEEP and CATTLE, and also in humans.


A general term for single-celled rounded fungi that reproduce by budding. Brewers' and bakers' yeasts are SACCHAROMYCES CEREVISIAE; therapeutic dried yeast is YEAST, DRIED.


An opening or hole in the ESOPHAGUS that is caused by TRAUMA, injury, or pathological process.


A thin membrane that lines the CEREBRAL VENTRICLES and the central canal of the SPINAL CORD.


The premier bibliographic database of the NATIONAL LIBRARY OF MEDICINE. MEDLINE® (MEDLARS Online) is the primary subset of PUBMED and can be searched on NLM's Web site in PubMed or the NLM Gateway. MEDLINE references are indexed with MEDICAL SUBJECT HEADINGS (MeSH).


A 20-carbon branched chain fatty acid. In phytanic acid storage disease (REFSUM DISEASE) this lipid may comprise as much as 30% of the total fatty acids of the plasma. This is due to a phytanic acid alpha-hydroxylase deficiency.


Form of chemistry concerned with discovering methods for transmuting base metals into gold and with finding an elixir for eternal youth.


Acyclic diterpene used in making synthetic forms of vitamin E and vitamin K1.


The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


alpha-Defensins
Antimicrobial Peptides, Neutrophil

DEFENSINS found in azurophilic granules of neutrophils and in the secretory granules of intestinal PANETH CELLS.


Clinical encounters in which patients receive healthcare from one or more health professionals, in a group setting. These may include patient education and counseling, physical examination, and clinical support. Patients usually share a mutual attribute such as a medical condition.


Group behavior toward others by virtue of their group membership.


Informed consent given by a parent on behalf of a minor or otherwise incompetent child.


The orderly segregation of CHROMOSOMES during MEIOSIS or MITOSIS.


Decompressive Craniotomy
Decompressive Craniectomy

Excision of part of the skull. This procedure is used to treat elevated intracranial pressure that is unresponsive to conventional treatment.


A condition in which total serum protein level is below the normal range. Hypoproteinemia can be caused by protein malabsorption in the gastrointestinal tract, EDEMA, or PROTEINURIA.


A technique used to separate particles according to their densities in a continuous density gradient. The sample is usually mixed with a solution of known gradient materials and subjected to centrifugation. Each particle sediments to the position at which the gradient density is equal to its own. The range of the density gradient is usually greater than that of the sample particles. It is used in purifying biological materials such as proteins, nucleic acids, organelles, and cell types.


Treatment of the skin with flashlamps of prescribed wavelengths, fluence, and pulse durations which target specific chromophores to induce photothermolysis at specific locations in the skin such as at the HAIR FOLLICLE or SPIDER VEINS.


A phylum of primitive invertebrate animals that exemplify a simple body organization. Trichoplax adhaerens is considered a key species for early metazoan evolution.


Nerve fibers which project from sympathetic ganglia to synapses on target organs. Sympathetic postganglionic fibers use norepinephrine as transmitter, except for those innervating eccrine sweat glands (and possibly some blood vessels) which use acetylcholine. They may also release peptide cotransmitters.


Solutions that have a greater osmotic pressure than a reference solution such as blood, plasma, or interstitial fluid.


Pharmacologic agents in the form of a mist or spray delivered into the body through the mouth.


Vaccines or candidate vaccines used to prevent infection with ROTAVIRUS.


Phosphotransferases (Carboxyl Group Acceptor)

A class of enzymes that transfers phosphate groups and has a carboxyl group as an acceptor. EC 2.7.2.


Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.


A mixed adenocarcinoma and squamous cell or epidermoid carcinoma.


The horn of an animal of the deer family, typically present only in the male. It differs from the HORNS of other animals in being a solid, generally branched bony outgrowth that is shed and renewed annually. The word antler comes from the Latin anteocularis, ante (before) + oculus (eye). (From Webster, 3d ed)


Vermox
Wormkuur
Bantenol
Boots Threadworm Treatment
Pripsen Mebendazole
Vermidil
Mebendan
Banworm
Anti-Worm
Mebenvet
R17635
Sufil
Vermicol
Lomper
Sqworm
Surfont
Madicure
Mebendazole
Telmin

A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.


Refusal to take part in activities or procedures that are requested or expected of an individual. This may include refusal by HEALTH PERSONNEL to participate in specific medical procedures or refusal by PATIENTS or members of the public to take part in clinical trials or health promotion programs.


Diseases that are underfunded and have low name recognition but are major burdens in less developed countries. The World Health Organization has designated six tropical infectious diseases as being neglected in industrialized countries that are endemic in many developing countries (HELMINTHIASIS; LEPROSY; LYMPHATIC FILARIASIS; ONCHOCERCIASIS; SCHISTOSOMIASIS; and TRACHOMA).


A genus of gram-negative, anaerobic cocci parasitic in the mouth and in the intestinal and respiratory tracts of man and other animals.


A non-iodinated derivative of amiodarone that is used for the treatment of ARRHYTHMIA.


Facilities which administer the delivery of mental health counseling services to children.


A class of free-living freshwater flatworms of North America.


A treatment method in which patients are under direct observation when they take their medication or receive their treatment. This method is designed to reduce the risk of treatment interruption and to ensure patient compliance.


Movement of a part of the body for the purpose of communication.


The central part of the body to which the neck and limbs are attached.


Neutrons, the energy of which exceeds some arbitrary level, usually around one million electron volts.


A carcinogenic mycotoxin produced in high yields by strains of the common molds, Aspergillus versicolor, A. nidulans, and an unidentified species of Bipolaris. It causes necrosis of the liver and kidney and has an inhibitory effect on orotic acid incorporation into nuclear RNA.


INTERNEURONS with projections to the contralateral side of the SPINAL CORD. Both excitatory and inhibitory interneurons are involved in coordinating alternative left-right activities during LOCOMOTION.


A pyrazole diuretic with long duration and high capacity of action. It was proposed for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects.


The plan, delineation, and location of actual structural elements of dentures. The design can relate to retainers, stress-breakers, occlusal rests, flanges, framework, lingual or palatal bars, reciprocal arms, etc.


Viruses whose taxonomic relationships have not been established.


A plant genus of the family CARYOPHYLLACEAE. Members contain dianthins, which are ribosome inactivating proteins.


An opening through the NUCLEAR ENVELOPE formed by the nuclear pore complex which transports nuclear proteins or RNA into or out of the CELL NUCLEUS and which, under some conditions, acts as an ion channel.


Works about the literary and oral genre expressing meaning via symbolism and following formal or informal patterns.


Specially designed endoscopes for visualizing the interior surface of the colon.


Works about the temporal sequence of events.


Myroxylon
Myroxylon balsamum
Myroxylon pereirae

A plant genus of the family FABACEAE that is a source of aromatic resinous balsams (Balsam of Tolu and Balsam of Peru) used in perfumery and as a constituent in cough syrups and lozenge.


Minute free-floating animal organisms which live in practically all natural waters.


Accumulation or retention of free fluid within the peritoneal cavity.


Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.


Compounds with a five-membered heterocyclic ring with two nitrogens and a keto OXYGEN. Some are inhibitors of TNF-ALPHA production.


The complex processes of initiating CELL DIFFERENTIATION in the embryo. The precise regulation by cell interactions leads to diversity of cell types and specific pattern of organization (EMBRYOGENESIS).


A form of PSYCHOTHERAPY that centers on the individuals as the experts in their own lives and views problems as separate from people. It is assumed that people have many skills, competencies, beliefs, values, commitments, and abilities that will assist them to reduce the influence of problems in their lives.


A skin carcinoma that histologically exhibits both basal and squamous elements. (From Dorland, 27th ed)


The purposeful manipulation of plant species with the goal of creating desired genotypes and phenotypes, using techniques such as controlled pollination and or genetic engineering, followed by artificial selection of progeny.


A selective type of autophagy in which a specific set of cytosolic proteins are moved across the membrane of the LYSOSOMES by protein translocation, rather than by invagination of the lysosomal membrane. The proteins that will be degraded by chaperone-mediated autophagy (CMA) contain a CMA-targeting motif that, when exposed, is recognized by the cytosolic chaperone HSPA8 (aka Hsc70) and cochaperones which deliver the protein to LAMP2A monomers on the lysosome cell surface for translocation via the LAMP2A translocation complex. CMA is distinguished from CHAPERONE-ASSISTED-SELECTIVE AUTOPHAGY - a type of selective MACROAUTOPHAGY.


A species of anaerobic bacteria, in the family Lachnospiraceae, found in RUMINANTS. It is considered both gram-positive and gram-negative.


Compounds that contain the structure 1,4-dioxane.


The surgical removal of a tooth. (Dorland, 28th ed)


Compounds with three fused rings that appear like a naphthalene fused to piperidone or like a benz(de)isoquinoline-1,3-dione (not to be confused with BENZYLISOQUINOLINES which have a methyl separating the naphthyl from the benzyl rings). Members are CYTOTOXINS.


A genus of RNA viruses in the family BIRNAVIRIDAE infecting birds. It is transmitted horizontally with no known vectors. The type species is INFECTIOUS BURSAL DISEASE VIRUS.


Symptoms of cerebral hypoperfusion or autonomic overaction which develop while the subject is standing, but are relieved on recumbency. Types of this include NEUROCARDIOGENIC SYNCOPE; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME; and neurogenic ORTHOSTATIC HYPOTENSION. (From Noseworthy, JH., Neurological Therapeutics Principles and Practice, 2007, p2575-2576)


A form-genus of CYANOBACTERIA in the order Oscillatoriales. They are non-heterocystous but may carry out NITROGEN FIXATION under microaerobic conditions. Some smaller members have undergone transfer to the form-genus Leptolyngbya.


An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.


A plant family of the order SOLANALES, class MAGNOLIOPSIDA. Among the most noted are POTATOES; TOMATOES; CAPSICUM (green and red peppers); TOBACCO; and BELLADONNA.


A genus of fungi in the phylum BLASTOCLADIOMYCOTA. They exhibit complex life cycles and are parasitic on the larvae of MOSQUITOES.


The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.


Recurrent or persistent involuntary SPASM of the outer muscles of the VAGINA, occurring during vaginal penetration.


Macrophages found in the TISSUES, as opposed to those found in the blood (MONOCYTES) or serous cavities (SEROUS MEMBRANE).


A multifocal uveitis syndrome involving the RETINAL PIGMENT EPITHELIUM and capillary layer of the CHOROID. It is characterized by chronic UVEITIS and multiple CHOROID lesions referred to as white dots, blurry vision, floaters, sensitivity to light, blind spots, and eye discomfort.


A plant genus of the family AMARANTHACEAE, order Caryophyllales, which has been used in traditional medicine (MEDICINE, CHINESE TRADITIONAL).


OXAZINES with a keto oxygen and a fused BENZENE ring.


Studies and research concerning the psychological, educational, social, vocational, industrial, and economic aspects of REHABILITATION.


A plant genus of the family BALANOPHORACEAE which contains thonningianins (TANNINS).


Syphilis serodiagnosis employing as the antigen Treponema pallidum obtained from rabbit syphilis orchitis. Treponemes are kept alive for a few hours in a special medium. When syphilitic serum and complement are added and incubated, the treponemes are immobilized, i.e., stop moving.


The plan and delineation of prostheses in general or a specific prosthesis.


A genus of RNA viruses in the family BIRNAVIRIDAE infecting fish, mollusks, and crustaceans. It is transmitted both vertically and horizontally with no known vectors. The natural hosts are salmonids and the type species is INFECTIOUS PANCREATIC NECROSIS VIRUS.


A plant genus of the family ASTERACEAE. The common name of cudweed is also used for other plants including Evax, Hesperevax, Pseudognaphalium, and Omalotheca. The common name of everlasting is also used for other plants including Anaphalis, Antennaria, HELICHRYSUM, Gamochaeta, and Pseudognaphalium.


The amount that a health care institution or organization pays for its drugs. It is one component of the final price that is charged to the consumer (FEES, PHARMACEUTICAL or PRESCRIPTION FEES).


A genus of ciliate protozoa having a dorsoventrally flattened body with widely spaced rows of short bristle-like cilia on the dorsal surface.


A species of gram-negative bacteria causing mild ANAPLASMOSIS in CATTLE. It also can infect SHEEP and GOATS. It is transmitted by TICKS.


An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.


The process of finding chemicals for potential therapeutic use.


Devices that babies can suck on when they are not feeding. The extra sucking can be comforting to the babies and pacify them. Pacifiers usually are used as a substitute for the thumb in babies who suck on their thumb or fingers almost constantly.


A radioactive element of the alkaline earth series of metals. It has the atomic symbol Ra and atomic number 88. Radium is the product of the disintegration of URANIUM and is present in pitchblende and all ores containing uranium. It is used clinically as a source of beta and gamma-rays in radiotherapy, particularly BRACHYTHERAPY.


GASTRITIS with atrophy of the GASTRIC MUCOSA, the GASTRIC PARIETAL CELLS, and the mucosal glands leading to ACHLORHYDRIA. Atrophic gastritis usually progresses from chronic gastritis.


A species of CAMPYLOBACTER isolated from the INTESTINES of PIGS with proliferative ENTERITIS. It is also found in CATTLE and in CRICETINAE and can cause enteritis in humans.


A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)


The ability of a protein to retain its structural conformation or its activity when subjected to physical or chemical manipulations.


Derivatives of the steroid androstane having two double bonds at any site in any of the rings.


The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.


A genus of HEPADNAVIRIDAE infecting birds but rarely causing clinical problems. Transmission is predominantly vertical. HEPATITIS B VIRUS, DUCK is the type species.


A genus of minute EUKARYOTES that are characterized by the preponderance of binucleate over uninucleate forms, the presence of several distinct granules in the karyosome, and the lack of a cystic stage. It is parasitic in the large intestine of humans and certain monkeys.


A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous or mucosal papillomas in cattle.


The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.


Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.


Ability to connect to the INTERNET and access services available there.


A saclike, glandular diverticulum on each ductus deferens in male vertebrates. It is united with the excretory duct and serves for temporary storage of semen. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


Three groups of arteries found in the eye which supply the iris, pupil, sclera, conjunctiva, and the muscles of the iris.


5,7,4'-trihydroxy-flavone, one of the FLAVONES.


The waterleaf plant family of the order Solanales, subclass Asteridae, class Magnoliopsida. They have alternate leaves, regular flowers with five-lobed corollas (united petals), and a one- or two-celled ovary.


A phosphodiesterase 4 inhibitor with antidepressant properties.


An antibiotic complex produced by Streptomyces kitasatoensis. The complex consists of a mixture of at least eight biologically active components, A1 and A3 to A9. Leucomycins have both antibacterial and antimycoplasmal activities.


Unstable isotopes of carbon that decay or disintegrate emitting radiation. C atoms with atomic weights 10, 11, and 14-16 are radioactive carbon isotopes.


A family of dioecious or monoecious evergreen trees belonging to the order Pinales, subclass Pinidaes, with spirally arranged, narrow or broad leaves often with parallel veins.


The continuous sequential physiological and psychological maturing of an individual from birth up to but not including ADOLESCENCE.


An adenoma containing fibrous tissue. It should be differentiated from ADENOFIBROMA which is a tumor composed of connective tissue (fibroma) containing glandular (adeno-) structures. (From Dorland, 27th ed)


Drug formulations or delivery systems intended to discourage the abuse of CONTROLLED SUBSTANCES. These may include physical barriers to prevent chewing or crushing the drug; chemical barriers that prevent extraction of psychoactive ingredients; agonist-antagonist combinations to reduce euphoria associated with abuse; aversion, where controlled substances are combined with others that will produce an unpleasant effect if the patient manipulates the dosage form or exceeds the recommended dose; delivery systems that are resistant to abuse such as implants; or combinations of these methods.


Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)


A plant family of the order Caryophyllales, subclass Caryophyllidae, class Magnoliopsida. Some members contain triterpenoid saponins.


Proteins that bind to and are involved in the metabolism of phosphate ions.


A measure of scientific precision, exactness, or correctness of quantitative or qualitative values, relative to the actual or true measurements.


Abnormal separation of bones, often from a LIGAMENT.


Sustaining BODY WEIGHT after BODY WEIGHT CHANGES have been achieved.


The classes of BONE MARROW-derived blood cells in the monocytic series (MONOCYTES and their precursors) and granulocytic series (GRANULOCYTES and their precursors).


An index of ARTERIAL STIFFNESS obtained from PULSE WAVE VELOCITY measurements between the heart and the ankle.


The normal process of elimination of fecal material from the RECTUM.


Adverse or favorable selection bias exhibited by insurers or enrollees resulting in disproportionate enrollment of certain groups of people.


CHOLESTENES with one or more double bonds and substituted by any number of keto groups.


A cutaneous necrobiotic disorder characterized by firm, yellow plaques or nodules, often in a periorbital distribution. It is often accompanied by an elevated ERYTHROCYTE SEDIMENTATION RATE; LEUKOPENIA; and MONOCLONAL GAMMOPATHY (IgG-kappa type) and systemic involvement.


Remote Operations (Robotics)
Robotics
Soft Robotics
Telerobotics

The application of electronic, computerized control systems to mechanical devices designed to perform human functions. Formerly restricted to industry, but nowadays applied to artificial organs controlled by bionic (bioelectronic) devices, like automated insulin pumps and other prostheses.


An order of nematodes of the subclass SECERNENTEA. Characteristics include an H-shaped excretory system with two subventral glands.


Fluorides, usually in pastes or gels, used for topical application to reduce the incidence of DENTAL CARIES.


A plant genus of the family FABACEAE. Members contain molluscicidal triterpene glycosides (TRITERPENES).


Azo compounds consisting of an aryl or alkyl group that is joined through two nitrogen atoms to an anion (R-N2+X-).


Transection or severing of an axon. This type of denervation is used often in experimental studies on neuronal physiology and neuronal death or survival, toward an understanding of nervous system disease.


Set of expectations that exempt persons from responsibility for their illness and exempt them from usual responsibilities.


A suspension of killed Yersinia pestis used for immunizing people in enzootic plague areas.


Surgery of the upper jaw bone usually performed to correct upper and lower jaw misalignment.


Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.


A genus of RNA protozoan viruses of the family TOTIVIRIDAE. Several different strains of Leishmania are infected by a variety of viral species. The type species is Leishmania RNA virus 1-1.


A plant genus of the family Asparagaceae that contains steroidal SAPONINS.


The real or apparent movement of objects through the visual field.


Language Comprehension Tests
Multilingual Aphasia Examination
Boston Diagnostic Aphasia Examination
Boston Naming Test
Language Tests
Vocabulary Tests
Comprehensive Aphasia Test

Tests designed to assess language behavior and abilities. They include tests of vocabulary, comprehension, grammar and functional use of language, e.g., Development Sentence Scoring, Receptive-Expressive Emergent Language Scale, Parsons Language Sample, Utah Test of Language Development, Michigan Language Inventory and Verbal Language Development Scale, Illinois Test of Psycholinguistic Abilities, Northwestern Syntax Screening Test, Peabody Picture Vocabulary Test, Ammons Full-Range Picture Vocabulary Test, and Assessment of Children's Language Comprehension.


The parts of a GENOME sequence that are involved with the different functions or properties of genomes as a whole as opposed to those of individual GENES.


Collection of granular epithelial cells in the uterine muscle beneath the placenta that develop during pregnancy in certain species of animals.


Excessive sweating. In the localized type, the most frequent sites are the palms, soles, axillae, inguinal folds, and the perineal area. Its chief cause is thought to be emotional. Generalized hyperhidrosis may be induced by a hot, humid environment, by fever, or by vigorous exercise.


Long chain organic acid molecules that must be obtained from the diet. Examples are LINOLEIC ACIDS and LINOLENIC ACIDS.


High temperature weather exceeding the average and of several weeks duration. Extreme heat is a dangerous situation that can bring on health emergencies in susceptible people.


The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.


A species of BORDETELLA with similar morphology to BORDETELLA PERTUSSIS, but growth is more rapid. It is found only in the RESPIRATORY TRACT of humans.


Acquired responses regularly manifested by tongue movement or positioning.


Degree of saltiness, which is largely the OSMOLAR CONCENTRATION of SODIUM CHLORIDE plus any other SALTS present. It is an ecological factor of considerable importance, influencing the types of organisms that live in an ENVIRONMENT.


Peptide hormones that cause an increase in the absorption of GLUCOSE by cells within organs such as LIVER; MUSCLE and ADIPOSE TISSUE. During normal metabolism insulins are produced by the PANCREATIC BETA CELLS in response to increased GLUCOSE. Natural and chemically-modified forms of insulin are also used in the treatment of GLUCOSE METABOLISM DISORDERS such as DIABETES MELLITUS.


A two-person sport in which the fists are skillfully used to attack and defend.


A species of mosquito in the genus Anopheles and the principle vector of MALARIA in Africa.


A weapon designed to explode when deployed. It frequently refers to a hollow case filled with EXPLOSIVE AGENTS.


Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.


Infection with any of the rotaviruses. Specific infections include human infantile diarrhea, neonatal calf diarrhea, and epidemic diarrhea of infant mice.


A genus of gram-negative, sheathed, rod-shaped bacteria in the order BURKHOLDERIALES.


A plant genus of the family MENISPERMACEAE. Members contain eletefine (a stephaoxocane alkaloid) and tropoloisoquinoline and protoberberine ALKALOIDS.


In horses, cattle, and other quadrupeds, the joint between the femur and the tibia, corresponding to the human knee.


Loss of a limb or other bodily appendage by accidental injury.


A genus of GRAM-POSITIVE ENDOSPORE-FORMING BACTERIA in the family Pasteuriaceae. It is transmitted via soil or waterborne SPORES.


Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.


Dedication or commitment shown by employees to organizations or institutions where they work.


Nurses who are specially trained to assume an expanded role in providing medical care under the supervision of a physician.


A family of gram-negative bacteria in the order Methylophilales.


The separation of particles from a suspension by passage through a filter with very fine pores. In ultrafiltration the separation is accomplished by convective transport; in DIALYSIS separation relies instead upon differential diffusion. Ultrafiltration occurs naturally and is a laboratory procedure. Artificial ultrafiltration of the blood is referred to as HEMOFILTRATION or HEMODIAFILTRATION (if combined with HEMODIALYSIS).


Methods of giving food to humans or animals.


Excessive winking; tonic or clonic spasm of the orbicularis oculi muscle.


A genus of gram-negative bacteria in the genus ACTINOBACILLUS, which is pathogenic for HORSES and PIGS.


Application of fingers with light pressure to the surface of the body to determine consistence of parts beneath in physical diagnosis; includes palpation for determining the outlines of organs.


A species of free-living soil amoeba in the family Balamuthiidae, causing AMEBIASIS and a deadly form of ENCEPHALITIS in humans.


An irrational reaction compounded of grief, loss of self-esteem, enmity against the rival and self criticism.


An estrogenic steroid produced by HORSES. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the URINE of pregnant mares.


The series of changes to the shape, size, components, and functions of an individual organism that occur over time as the organism progresses from its initial form to full size and maturity.


Consideration and concern for others, as opposed to self-love or egoism, which can be a motivating influence.


Diethers with the structure -C(OR'')(OR'''), where R'' and  R''' are not hydrogen. Mixed acetals have R'' and R''' groups which differ.


Inorganic or organic oxy acids of sulfur which contain the general formula RS2O2H.


A phylum of green plants comprising CHAROPHYCEAE (streptophyte green algae) and EMBRYOPHYTA (land plants).


Anniversaries
Dedications
Special Events
Anniversaries and Special Events

Occasions to commemorate an event or occasions designated for a specific purpose.