Ventral Tegmental Area
Area Tegmentalis Ventralis
Ventral Tegmental Area of Tsai

A region in the MESENCEPHALON which is dorsomedial to the SUBSTANTIA NIGRA and ventral to the RED NUCLEUS. The mesocortical and mesolimbic dopaminergic systems originate here, including an important projection to the NUCLEUS ACCUMBENS. Overactivity of the cells in this area has been suspected to contribute to the positive symptoms of SCHIZOPHRENIA.


Condensed Tannin
Anthocyanidin Polymers
Condensed Tannins
Procyanidins
Proanthocyanidins
Tannin, Condensed

Proanthocyanidins consisting exclusively of (epi)catechin.


IREBF1 Protein
MyD32 Protein
IRF-1 Transcription Factor
Interferon Regulatory Factor-1
Interferon-Stimulated Gene Factor 1
IRF-1 Protein
IREBF1 Transcription Factor
ISGF1 Transcription Factor

An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.


Tunica Intima
Vascular Intima
Venous Intima
Tunica Intima Vasorum
Arterial Intima

The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.


Audits, Medical
Audit, Medical
Medical Audits
Medical Audit

A detailed review and evaluation of selected clinical records by qualified professional personnel for evaluating quality of medical care.


Zinc Finger Protein 36
Tristetraprolin Protein
G0-G1 Switch Regulatory Protein 24
Tristetraprolin

A ZINC FINGER MOTIF containing transcription factor that was originally identified as one of the IMMEDIATE-EARLY PROTEINS. It shuttles between the CYTOPLASM and the CELL NUCLEUS and is involved in destabilization of mRNAs for TUMOR NECROSIS FACTOR-ALPHA.


Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.)


Equipment, Disposable
Disposable Equipment

Apparatus, devices, or supplies intended for one-time or temporary use.


HLA Class I Histocompatibility Antigen, B-14 alpha Chain

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*14 allele family.


Adrenal Insufficiency
Hypoadrenalism
Adrenal Gland Hypofunction

Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.


Bone Malalignment
Bone Misalignment
Bone Malposition

Displacement of bones out of line in relation to joints. It may be congenital or traumatic in origin.


A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin with a high affinity for the EPHA3 RECEPTOR; EPHA5 RECEPTOR; EPHA6 RECEPTOR; EPHA7 RECEPTOR; and EPHA8 RECEPTOR. It is found primarily in NERVE TISSUE.


Takayasu Disease
Takayasu Syndrome
Takayasu Arteritis
Takayasu's Arteritis
Pulseless Disease
Arteritis, Takayasu's
Aortitis Syndrome
Young Female Arteritis

A chronic inflammatory process that affects the AORTA and its primary branches, such as the brachiocephalic artery (BRACHIOCEPHALIC TRUNK) and CAROTID ARTERIES. It results in progressive arterial stenosis, occlusion, and aneurysm formation. The pulse in the arm is hard to detect. Patients with aortitis syndrome often exhibit retinopathy.


Dihydrofolate Dehydrogenase
Folic Acid Reductase
Tetrahydrofolate Dehydrogenase
Dihydrofolate Reductase

An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland, 27th ed) EC 1.5.1.3.


Garren-Edwards Gastric Bubble
Gastric Bubble
Gastric Balloon
Ballobes Balloon

An inflatable device implanted in the stomach as an adjunct to therapy of morbid obesity. Specific types include the silicone Garren-Edwards Gastric Bubble (GEGB), approved by the FDA in 1985, and the Ballobes Balloon.


Schwartzman Phenomenon
Shwartzman Reaction
Shwartzman Phenomenon
Schwartzman Reaction

Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow.


A genus of semi-aquatic elapid snake that inhabits coastal waters of the tropical Indian and Western Pacific Oceans.


A suborder of CRUSTACEA, order Diplostraca, comprising the water fleas. They are benthic filter feeders that consume PHYTOPLANKTON. The body is laterally compressed and enclosed in a bivalved carapace, from which the head extends.


Thimerosal
Thiomersalate
Mercurothiolate
Vitaseptol
Sodium Ethylmercurithiosalicylate
Merthiolate
Thiomersal

An ethylmercury-sulfidobenzoate that has been used as a preservative in VACCINES; ANTIVENINS; and OINTMENTS. It was formerly used as a topical antiseptic. It degrades to ethylmercury and thiosalicylate.


Antibiotic Resistance, Bacterial
Antibacterial Drug Resistance
Drug Resistance, Bacterial

The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).


Sleep Inducers
Sleep Aids, Pharmaceutical
Sleep Promoting Agents
Sleeping Pills

Drugs used to induce SLEEP, prevent SLEEPLESSNESS, or treat SLEEP INITIATION AND MAINTENANCE DISORDERS.


A pathologic entity characterized by deossification of a weight-bearing long bone, followed by bending and pathologic fracture, with inability to form normal BONY CALLUS leading to existence of the "false joint" that gives the condition its name. (Dorland, 27th ed)


Amine Precursor Uptake and Decarboxylation Cells

Cells with the capacity to take up and decarboxylate the amine precursors DIHYDROXYPHENYLALANINE or 5-HYDROXYTRYPTOPHAN. This is a property of endocrine cells of neural and non-neural origin. APUDOMA is a general term collectively applied to tumors associated with APUD cells.


Lyme Disease Vaccines
Vaccines, Lyme Disease

Vaccines or candidate vaccines used to prevent LYME DISEASE.


Allergic Angiitis
Allergic Granulomatous Angiitis
Allergic Granulomatous and Angiitis
Eosinophilic Granulomatous Vasculitis
Angiitis, Allergic Granulomatous
Vasculitis, Churg-Strauss
Granulomatous Allergic Angiitis
Churg-Strauss Syndrome
Allergic Granulomatosis
Allergic Angiitis and Granulomatosis

Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.


The waist circumference measurement divided by the hip circumference measurement. For both men and women, a waist-to-hip ratio (WHR) of 1.0 or higher is considered "at risk" for undesirable health consequences, such as heart disease and ailments associated with OVERWEIGHT. A healthy WHR is 0.90 or less for men, and 0.80 or less for women. (National Center for Chronic Disease Prevention and Health Promotion, 2004)


Biliary Tree
Biliary Tract
Biliary System


A semisynthetic analgesic used in the study of narcotic receptors.


In the late Middle Ages barbers who also let blood, sold unguents, pulled teeth, applied cups, and gave enemas. They generally had the right to practice surgery. By the 18th century barbers continued to practice minor surgery and dentistry and many famous surgeons acquired their skill in the shops of barbers. (From Castiglioni, A History of Medicine, 2d ed, pp402, 568, 658)


Progressive Nonfluent Aphasia
Primary Progressive Nonfluent Aphasia
PPA Syndrome
Non-fluent Primary Progressive Aphasia

A form of frontotemporal lobar degeneration and a progressive form of dementia characterized by motor speech impairment and AGRAMMATISM, with relative sparing of single word comprehension and semantic memory.


Aldose Reductase Ia
Aldehyde Reductase
Erythrose Reductase
Aldose Reductase
Xylose Reductase
Aldose Reductase Ib

An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.


Pseudomonas pyocyanea
Pseudomonas aeruginosa

A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.


Crossmatching, Tissue
HLA Typing
Tissue Typing
Histocompatibility Testing

Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed)


A parasite of carnivorous mammals that causes TRICHINELLOSIS. It is especially common in rats and in swine fed uncooked garbage. Human infection is initiated by the consumption of raw or insufficiently cooked pork or other meat containing the encysted larvae.


One of the minor protein components of skeletal and cardiac muscles. It functions as the calcium-binding component in a complex with BETA-TROPOMYOSIN; ACTIN; and MYOSIN and confers calcium sensitivity to the cross-linked actin and myosin filaments. Troponin itself is a complex of three regulatory proteins (TROPONIN C; TROPONIN I; and TROPONIN T).


Ribosome Subunits, 50S, Archaeal
50S Ribosomal Subunits, Archaeal
Ribosomal Subunits, Large, Archaeal
Ribosomal Subunits, 50S, Archaeal
Ribosome Subunits, Large, Archaeal
Archaeal Large Ribosome Subunits
Large Ribosome Subunits, Archaeal
Archaeal Large Ribosomal Subunits
Large Ribosomal Subunits, Archaeal
50S Ribosome Subunits, Archaeal

The large subunit of the archaeal 70s ribosome. It is composed of the 23S RIBOSOMAL RNA, the 5S RIBOSOMAL RNA, and about 40 different RIBOSOMAL PROTEINS.


The granting of a license to a hospital.


Preferred Provider Organization
Organizations, Preferred Provider
Preferred Provider Organizations

Arrangements negotiated between a third-party payer (often a self-insured company or union trust fund) and a group of health-care providers (hospitals and physicians) who furnish services at lower than usual fees, and, in return, receive prompt payment and an expectation of an increased volume of patients.


Protein Synthesis Antagonists
Protein Synthesis Inhibitors

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.


A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively.


Molecular Chaperone
Molecular Chaperones
Chaperones, Molecular
Chaperone, Molecular

A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.


The toothlike process on the upper surface of the axis, which articulates with the CERVICAL ATLAS above.


Ribonuclease H, Calf Thymus
RNase H
Ribonuclease H
Endoribonuclease H
RNAase H

A ribonuclease that specifically cleaves the RNA moiety of RNA:DNA hybrids. It has been isolated from a wide variety of prokaryotic and eukaryotic organisms as well as RETROVIRUSES.


Ribonucleic acid in chloroplasts having regulatory and catalytic roles as well as involvement in protein synthesis.


Fluoride-releasing restorative materials made by the sintering of metal (usually silver) particles to glass ionomer powder. Glass ionomers are fluoride-releasing cements that are not very durable. Sintering of the metal particles is a means of improving those physical properties that will make the glass ionomer cement more durable.


Leukocyte-Derived Seven-Transmembrane Domain Receptor

CXCR receptors with specificity for CXCL12 CHEMOKINE. The receptors may play a role in HEMATOPOIESIS regulation and can also function as coreceptors for the HUMAN IMMUNODEFICIENCY VIRUS.


Complement 3b Inhibitors
C3b Inhibitors
Complement 3b Inactivators
Conglutinogen Activating Factors
C3b Inactivators
Complement C3b Inactivators
Complement C3b Inactivator Proteins
Complement C3b Inhibitor Proteins

Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.


A small aquatic oviparous mammal of the order Monotremata found in Australia and Tasmania.


A species in the family ENTEROVIRUS infecting cattle.


Firdapse
Ruzurgi
Amifampridine
Amifampridine Phosphate
3,4-Diaminopyridine

4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.


A class of enzymes that catalyzes the phosphorylation of fructose in the presence of ATP. EC 2.7.1.-.


Immunogenetic Processes
Immunogenetic Phenomena
Immunogenetic Phenomenon
Immunogenetic Concepts

GENETIC PHENOMENA and processes involved in IMMUNITY and the immune response.


Autosomal Chromosome Disorders
Chromosomal Disorders
Chromosome Disorders
Chromosome Abnormality Disorders

Clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material (either a whole chromosome or a chromosome segment). (from Thompson et al., Genetics in Medicine, 5th ed, p429)


Mitochondrial UCPs
Uncoupling Proteins
Mitochondrial Uncoupling Proteins

Mitochondrial anion carrier proteins that function as dimers and form proton channels in the INNER MITOCHONDRIAL MEMBRANE which creates proton leaks and uncouples OXIDATIVE PHOSPHORYLATION from ATP synthesis, resulting in the generation of heat instead of ATP.


Adolescent Nutritional Physiological Phenomena

Adolescent Nutritional Physiological Phenomenon

Nutritional physiology of children aged 13-18 years.


Hematopoietic Stem Cell Mobilization
Stem Cell Mobilization

The release of stem cells from the bone marrow into the peripheral blood circulation for the purpose of leukapheresis, prior to stem cell transplantation. Hematopoietic growth factors or chemotherapeutic agents often are used to stimulate the mobilization.


Uridine Diphosphate N Acetylgalactosamine

A nucleoside diphosphate sugar which serves as a source of N-acetylgalactosamine for glycoproteins, sulfatides and cerebrosides.


Choreoathetosis, Pregnancy-Associated
Chorea, Pregnancy-Induced
Chorea Gravidarum

A rare movement disorder developed during PREGNANCY, characterized by involuntary jerky motion (CHOREA) and inability to maintain stable position of body parts (ATHETOSIS). RHEUMATIC FEVER and collagen vascular disorders are frequently associated with this disease. Chorea may vary from mild to severe and occurs in approximately 1 per 2,000 to 3,000 pregnancies. (From Md Med J 1997 Sep;46(8):436-9)


Infections, Enterobacteriaceae
Enterobacteriaceae Infections
Enterobacterial Infections
Infections, Enterobacterial
Cronobacter Infections

Infections with bacteria of the family ENTEROBACTERIACEAE.


An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.


Complement C2
C2 Complement
Complement Component 2
Complement 2

A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).


Infections, Bacillaceae
Bacillaceae Infections

Infections with bacteria of the family BACILLACEAE.


Franceschetti-Zwahlen-Klein Syndrome
Treacher Collins-Franceschetti Syndrome
Mandibulofacial Dysostosis (MFD1)
Treacher Collins Syndrome
Mandibulofacial Dysostosis

A hereditary disorder occurring in two forms: the complete form (Franceschetti's syndrome) is characterized by antimongoloid slant of the palpebral fissures, COLOBOMA of the lower lid, MICROGNATHIA and hypoplasia of the ZYGOMATIC ARCHES, and CONGENITAL MICROTIA. It is transmitted as an autosomal trait. The incomplete form (Treacher Collins syndrome) is characterized by the same anomalies in less pronounced degree. It occurs sporadically, but an autosomal dominant mode of transmission is suspected. (Dorland, 27th ed)


TRAF6
TRAF-6 Protein
TNF Receptor-Associated Factor 6

A signal transducing tumor necrosis factor receptor associated factor that is involved in regulation of NF-KAPPA B signalling and activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES.


Spindle Transfer Technique
Mitochondrial Replacement Therapy
Pronuclear Transfer Technique

In vitro fertilization technique that uses mitochondrial DNA from a healthy donor in order to prevent the transmission of MITOCHONDRIAL DISEASE.


Glycyrrhiza glabra
Liquorice
Licorice
Glycyrrhiza

A genus of leguminous herbs or shrubs whose roots yield GLYCYRRHETINIC ACID and its derivative, CARBENOXOLONE.


Methods and techniques used to modify or select cells and develop conditions for growing cells for biosynthetic production of molecules (METABOLIC ENGINEERING), for generation of tissue structures and organs in vitro (TISSUE ENGINEERING), or for other BIOENGINEERING research objectives.


Anti-Glomerular Basement Membrane Disease

An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.


Paternally Inherited
Paternal Effect
Paternal Inheritance
Inherited Paternally

A form of inheritance where the traits of the offspring are paternal in origin due to the expression of extra-nuclear genetic material such as MITOCHONDRIAL DNA or Y chromosome genes. CENTRIOLES are also paternally inherited.


Neurohypophyseal Peptides
Pituitrin
Pituitary Hormones, Posterior
Neurohypophyseal Hormones

A substance or extract from the neurohypophysis (PITUITARY GLAND, POSTERIOR).


Immunoelectrophoresis, Countercurrent
Electrosyneresis
Immunoelectroosmophoresis
Counterimmunoelectrophoresis
Immunoelectrophoresis, Crossover

Immunoelectrophoresis in which immunoprecipitation occurs when antigen at the cathode is caused to migrate in an electric field through a suitable medium of diffusion against a stream of antibody migrating from the anode as a result of endosmotic flow.


Intracranial Venous Angioma
Angioma, Venous, Central Nervous System
Cerebral Venous Angioma
Venous Angioma, Central Nervous System
CNS Venous Angioma
Central Nervous System Venous Angioma

A vascular anomaly characterized by a radial or wedge-shaped arrangement of dilated VEINS draining into a larger vein in the brain, spinal cord, or the meninges. Veins in a venous angioma are surrounded by normal nervous tissue, unlike a CENTRAL NERVOUS SYSTEM CAVERNOUS HEMANGIOMA that lacks intervening nervous tissue. Drainage of venous angioma is fully integrated with the body's venous system, therefore, in most cases there is no clinical signs and rare bleeding.


GA 733 Tumor-Associated Antigen
Tumor-Associated Antigen GA733
GA733 Tumor-Associated Antigen
Antigen, CD326
Ep-CAM
Tacstd1 Protein
Epithelial Cell Adhesion Molecule
GA733 Antigen
ESA Antigen
Epithelial Specific Antigen
CD326 Protein
EpCAM

A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells.  It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.


Laryngeal Prosthesis
Artificial Larynx
Voice Prosthesis
Artificial Larynges
Larynx, Artificial

A device, activated electronically or by expired pulmonary air, which simulates laryngeal activity and enables a laryngectomized person to speak. Examples of the pneumatic mechanical device are the Tokyo and Van Hunen artificial larynges. Electronic devices include the Western Electric electrolarynx, Tait oral vibrator, Cooper-Rand electrolarynx and the Ticchioni pipe.


A disease caused by any of a number of species of protozoa in the genus LEISHMANIA. There are four major clinical types of this infection: cutaneous (Old and New World) (LEISHMANIASIS, CUTANEOUS), diffuse cutaneous (LEISHMANIASIS, DIFFUSE CUTANEOUS), mucocutaneous (LEISHMANIASIS, MUCOCUTANEOUS), and visceral (LEISHMANIASIS, VISCERAL).


Cp 33-35
Scrapie Amyloid Precursor Protein
PrP-sen
Cp33-35, Scrapie
PrPC Proteins

Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.


Tic, Transient
Tics
Tic
Tic, Vocal
Habit Chorea
Tic, Motor
Habit Spasm
Habituation Spasm
Tic, Gestural

Habitual, repeated, rapid contraction of certain muscles, resulting in stereotyped individualized actions that can be voluntarily suppressed for only brief periods. They often involve the face, vocal cords, neck, and less often the extremities. Examples include repetitive throat clearing, vocalizations, sniffing, pursing the lips, and excessive blinking. Tics tend to be aggravated by emotional stress. When frequent they may interfere with speech and INTERPERSONAL RELATIONS. Conditions which feature frequent and prominent tics as a primary manifestation of disease are referred to as TIC DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, pp109-10)


Non-Disjunction, Genetic
Genetic Nondisjunction
Genetic Non-Disjunction
Nondisjunction, Genetic

The failure of homologous CHROMOSOMES or CHROMATIDS to segregate during MITOSIS or MEIOSIS with the result that one daughter cell has both of a pair of parental chromosomes or chromatids and the other has none.


Myosin Type I
Myosin IB
Myosin I
Myosin IA

A subclass of myosins found generally associated with actin-rich membrane structures such as filopodia. Members of the myosin type I family are ubiquitously expressed in eukaryotes. The heavy chains of myosin type I lack coiled-coil forming sequences in their tails and therefore do not dimerize.


A snow sport which uses skis to glide over the snow. It does not include water-skiing.


Meiosis-Activated Myelin Basic Protein Kinase p44(mpk)

A 44-kDa extracellular signal-regulated MAP kinase that may play a role the initiation and regulation of MEIOSIS; MITOSIS; and postmitotic functions in differentiated cells. It phosphorylates a number of TRANSCRIPTION FACTORS; and MICROTUBULE-ASSOCIATED PROTEINS.


Enterically-Transmitted Non-A, Non-B Hepatitis

Hepatitis, Viral, Non-A, Non-B, Enterically-Transmitted

Acute INFLAMMATION of the LIVER in humans; caused by HEPATITIS E VIRUS, a non-enveloped single-stranded RNA virus. Similar to HEPATITIS A, its incubation period is 15-60 days and is enterically transmitted, usually by fecal-oral transmission.


Son of Sevenless Proteins
SOS Proteins
Son of Sevenless Protein

A class of RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS that are genetically related to the Son of Sevenless gene from DROSOPHILA. Sevenless refers to genetic mutations in DROSOPHILA that cause loss of the R7 photoreceptor which is required to see UV light.


Computerized compilations of information units (text, sound, graphics, and/or video) interconnected by logical nonlinear linkages that enable users to follow optimal paths through the material and also the systems used to create and display this information. (From Thesaurus of ERIC Descriptors, 1994)


A plant genus in the family Boraginaceae, order Lamiales, subclass Asteridae. This is the True Heliotrope that should not be confused with an unrelated plant sometimes called Garden Heliotrope (VALERIAN).


Phosphoglycerate Phosphomutase
Phosphoglyceromutase
Phosphoglycerate Mutase
Glycerate (3-2)-Phosphomutase

An enzyme that catalyzes the conversion of 2-phospho-D-glycerate to 3-phospho-D-glycerate.


Gastrin-Secreting Cells
Gastrin Cells
G Cells

Endocrine cells which secrete GASTRIN, a peptide that induces GASTRIC ACID secretion. They are found predominantly in the GASTRIC GLANDS of PYLORIC ANTRUM in the STOMACH, but can also be found in the DUODENUM, nervous and other tissues.


Dihydrouracil Dehydrogenase
Dihydrouracil Dehydrogenase (NAD+)
Dihydrothymine Dehydrogenase (NAD)
Dihydrouracil Dehydrogenase (NAD)

An enzyme that catalyzes the oxidation of 5,6-dihydrouracil to URACIL using NAD as a cofactor. This enzyme also plays a role in the catabolism of the antimetabolite 5-FLUOROURACIL.


Tests, Pregnancy
Pregnancy Test
Pregnancy Tests
Test, Pregnancy

Tests to determine whether or not an individual is pregnant.


Nursing Students
Nursing Student
Student, Nursing
Pupil Nurses
Nurses, Pupil
Students, Nursing

Individuals enrolled in a school of nursing or a formal educational program leading to a degree in nursing.


A worm-like blind tube extension from the CECUM.


Atrial Function, Left
Left Atrial Function

The hemodynamic and electrophysiological action of the LEFT ATRIUM.


Extravasation of Diagnostic, Therapeutic Materials

Extravasation of Diagnostic and Therapeutic Materials

The escape of diagnostic or therapeutic material from the vessel into which it is introduced into the surrounding tissue or body cavity.


Curcumin
Diferuloylmethane
Turmeric Yellow

A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.


Congenital Fissure of the Abdominal Cavity

A congenital defect with major fissure in the ABDOMINAL WALL lateral to, but not at, the UMBILICUS. This results in the extrusion of VISCERA. Unlike OMPHALOCELE, herniated structures in gastroschisis are not covered by a sac or PERITONEUM.


A family of non-enveloped viruses infecting mammals (MASTADENOVIRUS) and birds (AVIADENOVIRUS) or both (ATADENOVIRUS). Infections may be asymptomatic or result in a variety of diseases.


Drugs, Generic
Drugs, Nonproprietary
Generic Drugs

Drugs whose drug name is not protected by a trademark. They may be manufactured by several companies.


A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh.


Tomography, Optical Coherence
Optical Coherence Tomography
OCT Tomography

An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes.


Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.


Hippophae rhamnoides
Fructus Hippophae
Sea Buckthorn
Hippophae
Buckthorn, Sea

A plant genus of the family ELAEAGNACEAE. Linoleic (18:2n-6) and alpha-linolenic acids (18:3n-3) comprised about 70% of seed oil fatty acids. This is unrelated to 'artificial sea buckthorn oil'. This genus does not belong to the buckthorn family (RHAMNACEAE).


Hyperbilirubinemia, Neonatal
Neonatal Hyperbilirubinemia
Direct Hyperbilirubinemia, Neonatal
Hyperbilirubinemia During Infancy
Indirect Hyperbilirubinemia, Neonatal

Accumulation of BILIRUBIN, a breakdown product of HEME PROTEINS, in the BLOOD during the first weeks of life. This may lead to NEONATAL JAUNDICE. The excess bilirubin may exist in the unconjugated (indirect) or the conjugated (direct) form. The condition may be self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) or pathological with toxic levels of bilirubin.


Vascular Endothelial Growth Factor Receptor-3

A vascular endothelial cell growth factor receptor whose expression is restricted primarily to adult lymphatic endothelium. VEGFR-3 preferentially binds the vascular endothelial growth factor C and vascular endothelial growth factor D and may be involved in the control of lymphangiogenesis.


Lymphoma, T Cell, Peripheral
Lymphoma, T-Cell, Peripheral
T-Cell Lymphoma, Peripheral
Peripheral T-Cell Lymphoma

A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymphoma (LYMPHOMA, LARGE-CELL, IMMUNOBLASTIC), this group's unique features warrant separate treatment.


Staff Privileges, Medical
Medical Staff Privileges, Nonphysician
Medical Staff Privileges

Those rights or activities which are specific to members of the institution's medical staff, including the right to admit private patients.


Formol Formalin Formaldehyde Methanal Oxomethane

A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)


Chonemorpha Acokanthera Asclepiadaceae Plumeria Rhazya Apocynaceae Cerbera Gongronema Carissa Cryptostegia Himatanthus Gomphocarpus Caralluma

A plant genus of the family APOCYNACEAE that contains plumericin, uleine and demethoxyaspidospermine.


Mimae Infections
Infections, Acinetobacter
Infections, Mimae
Acinetobacter Infections

Infections with bacteria of the genus ACINETOBACTER.


Tyrosine Kinase Linked Receptors
Receptors, Protein-Tyrosine Kinase
Receptor Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinase
Tyrosine Kinase Receptors
PTK Receptors
Protein-Tyrosine Kinase Receptor

A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity.


Hakim's Syndrome
Hydrocephalus, Normal-Pressure
Hakim Syndrome
Normal Pressure Hydrocephalus
Hydrocephalus, Normal Pressure
NPH (Normal Pressure Hydrocephalus)

A form of compensated hydrocephalus characterized clinically by a slowly progressive gait disorder (see GAIT DISORDERS, NEUROLOGIC), progressive intellectual decline, and URINARY INCONTINENCE. Spinal fluid pressure tends to be in the high normal range. This condition may result from processes which interfere with the absorption of CSF including SUBARACHNOID HEMORRHAGE, chronic MENINGITIS, and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp631-3)


Gastrin-Releasing Peptide Receptors
Bombesin Receptors
Gastrin-Releasing Peptide Receptor
Neuromedin B Receptor
Neuromedin B Receptors
Receptors, Bombesin
Bombesin Receptor
Receptors, Neuromedin B
Receptors, Gastrin-Releasing Peptide

Cell surface proteins that bind bombesin or closely related peptides with high affinity and trigger intracellular changes influencing the behavior of cells. Gastrin- releasing peptide (GRP); GRP 18-27 (neuromedin C), and neuromedin B are endogenous ligands of bombesin receptors in mammals.


Mouse, Inbred C3H
Mice, Inbred C3H
Mice, C3H
Mouse, C3H

An inbred strain of mouse that is used as a general purpose strain in a wide variety of RESEARCH areas including CANCER; INFECTIOUS DISEASES; sensorineural, and cardiovascular biology research.


Closable openings in the epidermis of plants on the underside of leaves. They allow the exchange of gases between the internal tissues of the plant and the outside atmosphere.


Culturally Competent Health Care
Cultural Care
Culturally Competent Care
Cross-Cultural Care
Culturally Congruent Care

Health care services that are respectful of and responsive to the health beliefs, practices and cultural and linguistic needs of diverse patients. The provider and the patient each bring their individual learned patterns of language and culture to the health care experience which must be transcended to achieve equal access and quality health care.


Seasonal Allergic Rhinitis
Rhinitis, Allergic, Seasonal
Hay Fever
Hayfever
Pollen Allergy
Pollinosis

Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.


Vitamin B1
Thiamine Mononitrate
Thiamin
Aneurin
Vitamin B 1
Thiamine


Receptor Up-Regulation
Up-Regulation (Physiology)
Upregulation
Up-Regulation

A positive regulatory process that increases ligand-receptor interactions. Increase in receptor binding after ligand exposure can result from receptor activation, aggregation, increase in half-life, and/or an increase in gene expression that leads to de novo receptor synthesis.


Erythrocytes
Blood Corpuscles, Red
Red Blood Corpuscles
Blood Cells, Red
Red Blood Cells

Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.


An order of amoeboid EUKARYOTES characterized by reticulating pseudopods and a complex life cycle with an alternation of generations. Most are less than 1mm in size and found in marine or brackish water.


An acute infection caused by the spore-forming bacteria BACILLUS ANTHRACIS. It commonly affects hoofed animals such as sheep and goats. Infection in humans often involves the skin (cutaneous anthrax), the lungs (inhalation anthrax), or the gastrointestinal tract. Anthrax is not contagious and can be treated with antibiotics.


Disease Frequency Surveys
Cross-Sectional Survey
Prevalence Studies
Cross Sectional Analysis
Analysis, Cross-Sectional
Surveys, Disease Frequency
Cross-Sectional Studies

Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.


A cytokine produced by bone marrow stromal cells that promotes the growth of B-LYMPHOCYTE precursors and is co-mitogenic with INTERLEUKIN-2 for mature T-LYMPHOCYTE activation.


phi 6 Phage
Bacteriophage phi 6
Pseudomonas phage phi 6
Phage phi 6

Virulent bacteriophage and sole member of the genus Cystovirus that infects Pseudomonas species. The virion has a segmented genome consisting of three pieces of doubled-stranded DNA and also a unique lipid-containing envelope.


Cytochrome P-450 CYP2C8 Inducers
CYP2C8 Inducers
P450 CYP2C8 Inducers

Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2C8.


Fat Embolism
Embolism, Fat
Fat Embolism Syndrome

Blocking of a blood vessel by fat deposits in the circulation. It is often seen after fractures of large bones or after administration of CORTICOSTEROIDS.


Deep Brain Stimulation
Brain Stimulation, Deep
Electrical Stimulation of the Brain

Therapy for MOVEMENT DISORDERS, especially PARKINSON DISEASE, that applies electricity via stereotactic implantation of ELECTRODES in specific areas of the BRAIN such as the THALAMUS. The electrodes are attached to a neurostimulator placed subcutaneously.


Cosmic Radiation
HZE Particles
Radiation, Cosmic

High-energy radiation or particles from extraterrestrial space that strike the earth, its atmosphere, or spacecraft and may create secondary radiation as a result of collisions with the atmosphere or spacecraft.


Sulfation Factor
Somatomedins
Insulin-Like Growth Factors
Somatomedin
Insulin Like Growth Factors

Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.


Technical Assistance for Health Planning

The provision of expert assistance in developing health planning programs, plans as technical materials, etc., as requested by Health Systems Agencies or other health planning organizations.


Angioplasty, Transluminal, Percutaneous, Laser

Percutaneous Transluminal Laser Angioplasty

Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.


Wildfires
Wild Fires
Brush Fires
Wildland Fires
Forest Fires

Fires that occur outdoors in the natural environment caused by natural forces or human activity.


The region of the stem beneath the stalks of the seed leaves (cotyledons) and directly above the young root of the embryo plant. It grows rapidly in seedlings showing epigeal germination and lifts the cotyledons above the soil surface. In this region (the transition zone) the arrangement of vascular bundles in the root changes to that of the stem. (From Concise Dictionary of Biology, 1990)


Endocytic/exocytic CELL MEMBRANE STRUCTURES rich in glycosphingolipids, cholesterol, and lipid-anchored membrane proteins that function in ENDOCYTOSIS (potocytosis), transcytosis, and SIGNAL TRANSDUCTION. Caveolae assume various shapes from open pits to closed vesicles. Caveolar coats are composed of CAVEOLINS.


Maximal Midexpiratory Flow Rate
Forced Expiratory Flow 025-075 Percent
FEF 25-75 Percent
Flow Rate, Maximal Midexpiratory
MMFR

Measurement of rate of airflow over the middle half of a FORCED VITAL CAPACITY determination (from the 25 percent level to the 75 percent level). Common abbreviations are MMFR and FEF 25%-75%.


beta-Crystallin
Crystallins, beta
beta-Crystallins

A class of crystallins that provides refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Beta-crystallins are similar in structure to GAMMA-CRYSTALLINS in that they both contain Greek key motifs. Beta-crystallins exist as oligomers formed from acidic (BETA-CRYSTALLIN A CHAIN) and basic (BETA-CRYSTALLIN B CHAIN) subunits.


The process by which the CYTOPLASM of a cell is divided.


Carbochromen
Carbocromene
Intensain
Chromonar
Carbocromen
Carbochromene
Chromonar Hydrochloride
Cardiocap
Intercordin


Delphinapterus leucas
White Whale
Beluga Whale

The species Delphinapterus leucas, in the family Monodontidae, found primarily in the Arctic Ocean and adjoining seas. They are small WHALES lacking a dorsal fin.


Oncogene Protein myb
Oncogene Proteins myb
p48(v-myb)
v-myb Proteins
Oncogene Proteins v-myb
myb Oncogene Proteins
Oncogene Products v-myb
v-myb Protein

Transforming proteins coded by myb oncogenes. Transformation of cells by v-myb in conjunction with v-ets is seen in the avian E26 leukemia virus.


gag Proteins, Human Immunodeficiency Virus

gag Gene Products, Human Immunodeficiency Virus

Proteins encoded by the GAG GENE of the HUMAN IMMUNODEFICIENCY VIRUS.


Antennapedia Protein
Antennapedia Homeodomain Protein

Antennapedia homeodomain protein is a homeobox protein involved in limb patterning in ARTHROPODS. Mutations in the gene for the antennapedia homeodomain protein are associated with the conversion of antenna to leg or leg to antenna DROSOPHILA.


Cerebral Microangiopathies
Cerebral Small Vessel Diseases
Cerebral Small Vessel Disease

Pathological processes or diseases where cerebral MICROVESSELS show abnormalities. They are often associated with aging, hypertension and risk factors for lacunar infarcts (see LACUNAR INFARCTION); LEUKOARAIOSIS; and CEREBRAL HEMORRHAGE.


Cytochromes, Heme b
Cytochrome b Group
Cytochromes Type b

Cytochromes (electron-transporting proteins) with protoheme (HEME B) as the prosthetic group.


rab GTPases
rab G-Proteins
rab GTP-Binding Proteins

A large family of MONOMERIC GTP-BINDING PROTEINS that play a key role in cellular secretory and endocytic pathways.


Intellectual or mental process whereby an organism obtains knowledge.


Fluoximesteron Halotestin Android-F Stenox Fluoxymesterone

An anabolic steroid that has been used in the treatment of male HYPOGONADISM, delayed puberty in males, and in the treatment of breast neoplasms in women.


Common name for small PASSERIFORMES in the family Fringillidae. They have a short stout bill (BEAK) adapted for crushing SEEDS. Some species of Old World finches are called CANARIES.


BIRDS that hunt and kill other animals, especially higher vertebrates, for food. They include the FALCONIFORMES order, or diurnal birds of prey, comprised of EAGLES, falcons, HAWKS, and others, as well as the STRIGIFORMES order, or nocturnal birds of prey, which includes OWLS.


Vicarious Traumatization
Vicarious Trauma
Compassion Fatigue
Secondary Traumatization
Secondary Trauma
Secondary Traumatic Stress

Emotional distress caused by repeated or prolonged expression of compassion or empathy. It may occur in individuals working in care giving professions.


Atherectomy
Percutaneous Transluminal Atherectomy
Transluminal Atherectomy
Percutaneous Atherectomy

Endovascular procedure in which atheromatous plaque is excised by a cutting or rotating catheter. It differs from balloon and laser angioplasty procedures which enlarge vessels by dilation but frequently do not remove much plaque. If the plaque is removed by surgical excision under general anesthesia rather than by an endovascular procedure through a catheter, it is called ENDARTERECTOMY.


A pattern recognition receptor that binds several forms of imidazo-quinoline including the antiviral compound Imiquimod.


Notch1 Protein
Notch1 Receptor
Receptor, Notch1

A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS for multiple cellular processes. It is widely expressed during EMBRYOGENESIS and is essential for EMBRYONIC DEVELOPMENT.


Germline Adult Stem Cells
Spermatogonial Progenitor Cells
Adult Germline Stem Cells

Progenitor stem cells found in the testicles.


Stunting
Stunted Growth
Growth Disorders

Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth.


rac GTP-Binding Proteins
rac Proteins
rac G Protein

A sub-family of RHO GTP-BINDING PROTEINS that is involved in regulating the organization of cytoskeletal filaments. This enzyme was formerly listed as EC 3.6.1.47.


Solute Carrier Family 21 Member 8 Protein

Solute Carrier Organic Anion Transporter Family Member 1B3

Liver-Specific Organic Anion Transporter-2

A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.


Surgical removal of a section of the iris.


Bacterial Chromatophores
Chromatophores, Bacterial

Organelles of phototrophic bacteria which contain photosynthetic pigments and which are formed from an invagination of the cytoplasmic membrane.


Adrenergic alpha-1 Receptor Agonist
Adrenergic alpha-1 Receptor Agonists
Adrenergic alpha-1 Agonists
Adrenergic alpha1-Agonists

Compounds that bind to and activate ADRENERGIC ALPHA-1 RECEPTORS.


Alcohol Consumption
Alcohol Drinking Habits
Drinking, Alcohol
Alcohol Drinking

Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.


Hu-man-teng
Jessamine, Yellow
Yellow-Jessamine
Woodbine
Gelsemium

A plant genus of the family LOGANIACEAE (classified by some botanists as Gelsemiaceae). The sometimes used common name of trumpet flower is also used for DATURA.


Heterotopic Transplantation
Transplantation, Heterotopic

Transplantation of tissue typical of one area to a different recipient site. The tissue may be autologous, heterologous, or homologous.


Antiretroviral Agents
Anti-Retroviral Agents

Agents used to treat RETROVIRIDAE INFECTIONS.


Tumor Necrosis Factor Ligand Superfamily Member 6

A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.


Ecotropic Virus Integration Site 1 Protein Homolog

Myelodysplasia Syndrome-Associated Protein 1

A DNA binding protein, transcriptional regulator, and proto-oncogene protein that contains 10 CYS2-HIS2 ZINC FINGERS. It functions as a positive or negative regulator of expression for target genes involved in organism development.


Receptor, Serotonin, 5-HT1B
Receptor, Serotonin Type 1Dbeta
5-HT1Dbeta Receptor
Serotonin 1B Receptor
5-HT(1Dbeta) Receptor
Serotonin 1Dbeta Receptor
Serotonin 1Dbeta Receptors
5-HT(1B) Receptor
Receptor, 5-Hydroxytryptamine 1B
5-HT1B Receptor
5-Hydroxytryptamine 1B Receptors
Serotonin 1D Beta Receptor
5-Hydroxytryptamine 1B Receptor

A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.


Amphiregulin-Associated Protein
Cytokine MK
Midkine

A developmentally regulated, HEPARIN-binding secreted growth factor homologous to pleiotrophin (PTN). It regulates cell proliferation through its interaction with ANAPLASTIC LYMPHOMA KINASE (ALK) and is involved in the formation of NEOINTIMA following arterial injury.


Order of Craniata containing one family Myxinidae. They have a partial cranium (skull), but no vertebrae, and so they are not true vertebrates.


Rous Sarcoma Virus-Transforming Protein pp60(v-src)

Avian Sarcoma Virus-Transforming Protein

A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine.


Whole Genome Sequencing
Complete Genome Sequencing

Techniques to determine the entire sequence of the GENOME of an organism or individual.


A highly toxic compound used as a gasoline additive. It causes acute toxic psychosis or chronic poisoning if inhaled or absorbed through the skin.


Dicarboxylic acids in which one of the carboxyl groups (-COOH) has been replaced by an aldehyde group (-CHO).


Polydeoxyribonucleotide Synthetases
DNA Joinases
Polydeoxyribonucleotide Ligases
T4 DNA Ligase
DNA Ligases

Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).


A preparation of METHIONINE that includes a mixture of D-methionine and L-methionine isomers.


Hip, Dislocation Of, Congenital
Hip Dysplasia, Congenital, Nonsyndromic
Dysplasia, Congenital Hip
Congenital Hip Displacement
Hip Displacement, Congenital
Dislocation, Congenital Hip
Dislocation Of Hip, Congenital
Congenital Hip Dislocation
Hip Dysplasia, Congenital
Congenital Hip Dysplasia
Hip Dislocation, Congenital
Congenital Dysplasia Of The Hip
Displacement, Congenital Hip

Congenital dislocation of the hip generally includes subluxation of the femoral head, acetabular dysplasia, and complete dislocation of the femoral head from the true acetabulum. This condition occurs in approximately 1 in 1000 live births and is more common in females than in males.


Wheat Germ Agglutinin Isolectin 2
Wheat Germ Agglutinin Isolectin 1
Wheat Germ Agglutinins
Lectins, Wheat Germ
Agglutinins, Wheat Germ
Wheat Germ Lectins
Lectins, Triticum Vulgare
Triticum Vulgare Lectins

Lectins purified from the germinating seeds of common wheat (Triticum vulgare); these bind to certain carbohydrate moieties on cell surface glycoproteins and are used to identify certain cell populations and inhibit or promote some immunological or physiological activities. There are at least two isoforms of this lectin.


Genes, nf1
Neurofibromatosis 1 Genes
Genes, nf 1
nf1 Genes
Genes, Neurofibromatosis 1

Tumor suppressor genes located on the long arm of human chromosome 17 in the region 17q11.2. Mutation of these genes is thought to cause NEUROFIBROMATOSIS 1, Watson syndrome, and LEOPARD syndrome.


TFF1 Peptide
Trefoil Factor-1
TFF1 Protein
Protein pS2
Trefoil Peptide 1

A 60 amino acid (6.5 kDa) trefoil factor that contains a single trefoil domain. It is expressed primarily by surface EPITHELIAL CELLS of the GASTRIC MUCOSA, where it associates with MUCIN 5AC.


Amla
Emblica officinalis
Mirobalanus embilica
Phyllanthus emblica

A plant species of the family EUPHORBIACEAE.


Ovine-Caprine Lentiviruses
Lentiviruses, Ovine-Caprine

A subgenus of LENTIVIRUS comprising viruses that produce multi-organ disease with long incubation periods in sheep and goats.


A plant genus of the family LILIACEAE. Members of this genus produce imperialine, a steroidal alkaloid which acts at muscarinic receptors.


Fees, Prescription
Prescription Fees
Dispensing Fees

The charge levied on the consumer for drugs or therapy prescribed under written order of a physician or other health professional.


Oral Surgical Procedure
Maxillofacial Procedures
Oral Surgical Procedures
Surgical Procedures, Oral
Surgical Procedure, Oral
Procedure, Oral Surgical
Procedures, Oral Surgical

Surgical procedures used to treat disease, injuries, and defects of the oral and maxillofacial region.


Hemophilus pleuropneumoniae
Actinobacillus pleuropneumoniae
Haemophilus pleuropneumoniae

A species of gram-negative, facultatively anaerobic coccobacillus-shaped bacteria that has been isolated from pneumonic lesions and blood. It produces pneumonia with accompanying fibrinous pleuritis in swine.


A plant genus of the family POACEAE that contains Hol l 1 and Hol l 5 allergens.


Comamonas testosteroni
Pseudomonas testosteroni

A species of gram-negative, aerobic rods formerly called Pseudomonas testosteroni. It is differentiated from other Comamonas species by its ability to assimilate testosterone and to utilize phenylacetate or maleate as carbon sources.


Suppressor of Cytokine Signaling 1 Protein

Suppressor of Cytokine Signaling Protein 1 -

A suppressor of cytokine signaling protein that consists of an N-terminal kinase-inhibitory region, a central SH2 DOMAIN, a characteristic C-terminal SOCS box (a 40-amino acid motif, which functions to recruit E3 UBIQUITIN-PROTEIN LIGASE COMPLEXES). SOCS1 functions as a negative regulator of CYTOKINES that signal through the JANUS KINASES-STAT 3 TRANSCRIPTION FACTOR (JAK/STAT3) pathway by inhibiting the activity of JANUS KINASES.


Rotarod Method
Rotarod Assay
Rotarod Performance Test
Rotarod Test

A performance test based on forced MOTOR ACTIVITY on a rotating rod, usually by a rodent. Parameters include the riding time (seconds) or endurance. Test is used to evaluate balance and coordination of the subjects, particular in experimental animal models for neurological disorders and drug effects.


Nonocclusion
Openbite
Apertognathia
Open Bite

A condition in which certain opposing teeth fail to establish occlusal contact when the jaws are closed.


Oncogene Protein p28(v-sis)
sis Oncogene Proteins
p28(v-sis)
Oncogene Proteins v-sis
Oncogene Products v-sis
Oncogene Proteins sis
v-sis Proteins

Transforming proteins coded by sis oncogenes. Transformation of cells by v-sis is related to its interaction with the PDGF receptor and also its ability to alter other transcription factors.


Maternal deaths resulting from complications of pregnancy and childbirth in a given population.


Personality Disorder, Paranoid
Paranoid Personality
Paranoid Personality Disorder

A personality disorder characterized by the avoidance of accepting deserved blame and an unwarranted view of others as malevolent. The latter is expressed as suspiciousness, hypersensitivity, and mistrust.


Staining of bands, or chromosome segments, allowing the precise identification of individual chromosomes or parts of chromosomes. Applications include the determination of chromosome rearrangements in malformation syndromes and cancer, the chemistry of chromosome segments, chromosome changes during evolution, and, in conjunction with cell hybridization studies, chromosome mapping.


Ganglion, Spinal
Spinal Ganglia
Dorsal Root Ganglia
Dorsal Root Ganglion
Ganglia, Spinal

Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain.


CCND1 Protein
Proto-Oncogene Protein bcl-1
bcl-1 Proto-Oncogene Proteins
Cyclin D1
bcl-1 Proto-Oncogene Products
Proto-Oncogene Proteins c-bcl-1
c-bcl-1 Proteins
Proto-Oncogene Products bcl-1
PRAD1 Protein
bcl1 Proto-Oncogene Proteins

Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.


Receptor, Fibroblast Growth Factor, Type 4

A fibroblast growth factor receptor that is mainly expressed in LUNG; KIDNEY; PANCREAS; and SPLEEN. It also plays an important role in SKELETAL MUSCLE development and can contribute to NEOPLASTIC CELL TRANSFORMATION.


Dominance, Ocular
Eye Dominance
Eyedness

The functional superiority and preferential use of one eye over the other. The term is usually applied to superiority in sighting (VISUAL PERCEPTION) or motor task but not difference in VISUAL ACUITY or dysfunction of one of the eyes. Ocular dominance can be modified by visual input and NEUROTROPHIC FACTORS.


Checkpoint Kinase 1
Checkpoint-1 Kinase
Chk1 Kinase
Chk1 Protein Kinase

A serine/threonine-specific protein kinase which is encoded by the CHEK1 gene in humans. Checkpoint kinase 1 (also known as Chk1) coordinates DNA damage response and cell cycle checkpoint response. Under these conditions, activation of Chk1 results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death, to prevent damaged cells from progressing through the cell cycle.


A flavanone glycoside found in CITRUS fruit peels.


A heterogeneous-nuclear ribonucleoprotein found associated with most nascent transcripts, most notably those of the landmark giant loops of amphibian lampbrush chromosomes.


State of mind or spirit that enables one to act in the face of perceived danger, difficulty, or pain.


ApoE4
Apo E4
Apo E-4
Apolipoprotein E4
Apolipoprotein E-4
Apo E epsilon 4

A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES.


ACNE-like skin eruptions caused by exposure to CHLORINE-containing compounds. Exposure can be by inhalation, ingestion, or through the skin. Chloracne is often seen in people who have occupational contact with chlorinated pesticides, wood preservatives, and sealants.


Ilizarov Technique
Ilizarov Method
Ilizarov Technic

A bone fixation technique using an external fixator (FIXATORS, EXTERNAL) for lengthening limbs, correcting pseudarthroses and other deformities, and assisting the healing of otherwise hopeless traumatic or pathological fractures and infections, such as chronic osteomyelitis. The method was devised by the Russian orthopedic surgeon Gavriil Abramovich Ilizarov (1921-1992). (From Bull Hosp Jt Dis 1992 Summer;52(1):1)


One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.


Lysyl Bradykinin
Lysine Bradykinin
Kallidin
Lys-Bradykinin
Kallidin, (D)-Isomer
Kallidin Tetraacetate
N2-L-Lysylbradykinin

A decapeptide bradykinin homolog cleaved from kininogen by kallikreins. It is a smooth-muscle stimulant and hypotensive agent that acts by vasodilatation.


Specialized tissues that are components of the lymphatic system. They provide fixed locations within the body where a variety of LYMPHOCYTES can form, mature and multiply. The lymphoid tissues are connected by a network of LYMPHATIC VESSELS.


Light-Curing of Dental Resins
Dental Bonding, Light-Cured
Light-Curing of Dental Cements
Light-Curing of Dental Adhesives

The hardening or polymerization of bonding agents (DENTAL CEMENTS) via exposure to light.


6-Ketoprostaglandin F1 alpha
6-Oxoprostaglandin F1 alpha
6-Keto-PGF1 alpha
6-Oxo-PGF1 alpha
6 Ketoprostaglandin F1 alpha

The physiologically active and stable hydrolysis product of EPOPROSTENOL. Found in nearly all mammalian tissue.


Basic Transcription Factor 2
TFIIH Transcription Factor
Transcription Factor IIH
Transcription Factor BTF2
Transcription Factor TFIIH
BTF2 Transcription Factor

A general transcription factor that is involved in basal GENETIC TRANSCRIPTION and NUCLEOTIDE EXCISION REPAIR. It consists of nine subunits including ATP-DEPENDENT DNA HELICASES; CYCLIN H; and XERODERMA PIGMENTOSUM GROUP D PROTEIN.


Protein Kinase C-theta
PRKCQ
Protein Kinase C theta
Protein Kinase C, theta
PKC-theta

A calcium-independent, phospholipid- and diacylglycerol-dependent, protein kinase C subtype that contains an N-terminal C2 DOMAIN and two diacylglycerol-binding ZINC FINGERS. It is expressed primarily by T-LYMPHOCYTES and localizes to IMMUNOLOGICAL SYNAPSES where it regulates downstream signaling for the activation, proliferation, and survival of mature T-cells. It plays a critical role in allergic, autoimmune, and alloimmune responses of TH2 CELLS and TH17 CELLS.


Lumbar Puncture
Spinal Puncture
Spinal Tap

Tapping fluid from the subarachnoid space in the lumbar region, usually between the third and fourth lumbar vertebrae.


Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.


Assessment, Process
Process Measures
Process Assessment (Health Care)
Process Assessment, Health Care

An evaluation procedure that focuses on how care is delivered, based on the premise that there are standards of performance for activities undertaken in delivering patient care, in which the specific actions taken, events occurring, and human interactions are compared with accepted standards.


Cell Adhesion Molecules, Neuronal
Neuronal Cell Adhesion Molecules
Axon-Associated Adhesion Molecules

Surface ligands that mediate cell-to-cell adhesion and function in the assembly and interconnection of the vertebrate nervous system. These molecules promote cell adhesion via a homophilic mechanism. These are not to be confused with NEURAL CELL ADHESION MOLECULES, now known to be expressed in a variety of tissues and cell types in addition to nervous tissue.


Ultrasonic Surgery
Ultrasonic Surgical Procedures

The use of HIGH-ENERGY SHOCK WAVES, in the frequency range of 20-60 kHz, to cut through or remove tissue. The tissue fragmentation by ultrasonic surgical instruments is caused by mechanical effects not heat as with HIGH-INTENSITY FOCUSED ULTRASOUND ABLATION.


Sympathetic Denervation
Denervation, Sympathetic
Sympathectomy

The removal or interruption of some part of the sympathetic nervous system for therapeutic or research purposes.


Adenocarcinoma, Preinvasive
Adenocarcinoma, Intraepithelial
Adenocarcinoma in Situ

A lesion with cytological characteristics associated with invasive adenocarcinoma but the tumor cells are confined to the GLANDULAR EPITHELIAL CELLS of origin. Adenocarcinoma in situ of the CERVIX and the LUNG are the most common.


Venous Sinus Thrombosis, Cranial
Sinus Thrombosis, Intracranial
Petrous Sinus Thrombophlebitis
Sinus Thrombosis
Petrous Sinus Thrombosis
Intracranial Sinus Thrombophlebitis
Cranial Sinus Thrombosis

Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.


Phosphorylation, Oxidative
Oxidative Phosphorylation

Electron transfer through the cytochrome system liberating free energy which is transformed into high-energy phosphate bonds.


Glycosides from DIGITALIS lanata leaf. Lanatoside C has actions similar to DIGOXIN. Mixtures of lanatosides A, B, and C have also been used. (From Martindale, The Extra Pharmacopoeia, 30th ed, p670)


Deficiency, Multiple Carboxylase, Late-Onset

Late-Onset Multiple Carboxylase Deficiency

Carboxylase Deficiency, Multiple, Late-Onset

Late-Onset Biotin-Responsive Multiple Carboxylase Deficiency

Multiple Carboxylase Deficiency, Late-Onset

The late onset form of MULTIPLE CARBOXYLASE DEFICIENCY (deficiency of the activities of biotin-dependent enzymes propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, and PYRUVATE CARBOXYLASE) due to a defect or deficiency in biotinidase which is essential for recycling BIOTIN.


Professions or other business activities directed to the cure and prevention of disease. For occupations of medical personnel who are not physicians but who are working in the fields of medical technology, physical therapy, etc., ALLIED HEALTH OCCUPATIONS is available.


Interphalangeal Joint of Hand
Interphalangeal Joint of Finger
Finger Joint

The articulation between the head of one phalanx and the base of the one distal to it, in each finger.


Leukemia, Radiation-Induced
Radiation-Induced Leukemia

Leukemia produced by exposure to IONIZING RADIATION or NON-IONIZING RADIATION.


Exodeoxyribonuclease V, beta Chain
Exodeoxyribonuclease V, gamma Chain
ATP-Dependent DNase
RecBC Deoxyribonuclease
Exodeoxyribonuclease V
RecBC DNase
RecBCD Enzyme
Exodeoxyribonuclease V, alpha Chain
Exonuclease V

An ATP-dependent exodeoxyribonuclease that cleaves in either the 5'- to 3'- or the 3'- to 5'-direction to yield 5'-phosphooligonucleotides. It is primarily found in BACTERIA.


An enzyme that catalyzes the formation of 7-phospho-2-keto-3-deoxy-D-arabinoheptonate from phosphoenolpyruvate and D-erythrose-4-phosphate. It is one of the first enzymes in the biosynthesis of TYROSINE and PHENYLALANINE. This enzyme was formerly listed as EC 4.1.2.15.


Brainstem Auditory Evoked Potential
Auditory Brainstem Responses
Evoked Response, Auditory, Brainstem
Brain Stem Auditory Evoked Potentials
Evoked Responses, Auditory, Brain Stem
Brainstem Auditory Evoked Potentials
Evoked Potentials, Auditory, Brain Stem
Evoked Responses, Auditory, Brainstem
Acoustic Evoked Brainstem Potential
Auditory Brainstem Evoked Response
Evoked Potential, Auditory, Brainstem
Acoustic Evoked Brain Stem Potentials
Acoustic Evoked Brain Stem Potential
Evoked Potentials, Auditory, Brainstem
Auditory Brain Stem Evoked Response
Evoked Response, Auditory, Brain Stem
Brain Stem Auditory Evoked Potential
Auditory Brainstem Evoked Responses
Auditory Brain Stem Responses
Acoustic Evoked Brainstem Potentials
Auditory Brain Stem Response
Auditory Brain Stem Evoked Responses

Electrical waves in the CEREBRAL CORTEX generated by BRAIN STEM structures in response to auditory click stimuli. These are found to be abnormal in many patients with CEREBELLOPONTINE ANGLE lesions, MULTIPLE SCLEROSIS, or other DEMYELINATING DISEASES.


Viral Infections
Virus Infections
Virus Diseases
Viral Diseases

A general term for diseases caused by viruses.


Simian Adenoviruses
Adenoviruses, Simian

Species of the genus MASTADENOVIRUS associated with respiratory and enteric infections in primate hosts.


Small, often pleomorphic, coccoid to ellipsoidal organisms occurring intracytoplasmically in circulating LYMPHOCYTES. They are the etiologic agents of tick-borne diseases of humans; DOGS; CATTLE; SHEEP; GOATS; and HORSES.


Institutions with permanent facilities and organized medical staff which provide the full range of hospital services primarily to a neighborhood area.


The local lymph node assay (LLNA) is an alternative method for the identification of chemicals that have the ability to cause skin sensitization and allergic contact dermatitis. Endpoints have been established so fewer animals are required and less painful procedures are used.


Fused Heterocyclic Compounds, Three-Ring

A class of heterocyclic compounds that include a three-ring fused structure. Both aromatic or non-aromatic ring structures are included in this category.


A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.


Conditioning, Psychological
Conditioning, Psychology
Social Learning Theory
Psychological Conditioning

Theory of observational learning that holds people have the ability to learn by simply watching others.


Camellia sinensis L. (formerly Thea sinensis) is an evergreen Asiatic shrub of the THEACEAE family. The infusion of leaves of this plant is used as Oriental TEA which contains CAFFEINE; THEOPHYLLINE; and epigallocatechin gallate.


Natriuretic Peptides
Natriuretic Peptide Hormones

Peptides that regulate the WATER-ELECTROLYTE BALANCE in the body, also known as natriuretic peptide hormones. Several have been sequenced (ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; C-TYPE NATRIURETIC PEPTIDE).


Caprine Arthritis-Encephalitis Viruses
Arthritis-Encephalitis Virus, Caprine
Virus, Caprine Arthritis-Encephalitis
Viruses, Caprine Arthritis-Encephalitis
Caprine arthritis-encephalitis virus
Arthritis-Encephalitis Viruses, Caprine
CAEV

A species of LENTIVIRUS, subgenus ovine-caprine lentiviruses (LENTIVIRUSES, OVINE-CAPRINE), closely related to VISNA-MAEDI VIRUS and causing acute encephalomyelitis; chronic arthritis; PNEUMONIA; MASTITIS; and GLOMERULONEPHRITIS in goats. It is transmitted mainly in the colostrum and milk.


Teen Pregnancy
Adolescent Pregnancy
Pregnancy, Teenage
Teenage Pregnancy
Pregnancy in Adolescence
Preteen Pregnancy
Pregnancy, Adolescent

Pregnancy in human adolescent females under the age of 19.


Single Kidney
Single Functioning Kidney
Solitary Kidney
Solitary Functioning Kidney
Unilateral Renal Agenesis
Unilateral Renal Hypoplasia

Either a single or a single functioning kidney due to NEPHRECTOMY, birth defects or other kidney diseases.


Nonmuscle Myosin Type IIB
Myosin IIB
Myosin B
Myosin Type IIB, Non-Muscle
Non-Muscle Myosin Type IIB

A nonmuscle isoform of myosin type II found predominantly in neuronal tissue.


GDF-9-Related Protein
Bone Morphogenetic Protein 15
Growth Differentiation Factor 9B
GDF-9 Related Factor
BMP-15
GDF-9B

A protein that plays a role in GRANULOSA CELLS where it regulates folliculogenesis. Mutations in the gene for bone morphogenetic protein 15 are linked to reproductive abnormalities such as PREMATURE OVARIAN FAILURE.


Consent Documents
Consent Forms
Informed Consent Documents
Informed Consent Forms

Documents describing a medical treatment or research project, including proposed procedures, risks, and alternatives, that are to be signed by an individual, or the individual's proxy, to indicate his/her understanding of the document and a willingness to undergo the treatment or to participate in the research.


Sulfur Reducing Bacteria
Sulfur-Reducing Bacteria

A group of gram-negative, anaerobic bacteria that is able to oxidize acetate completely to carbon dioxide using elemental sulfur as the electron acceptor.


Cephalotaxine Alkaloids
Harringtonines
Cephalotaxus Alkaloids

Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkaloid cephalotaxine and may be effective as antineoplastic agents.


National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division

National Academies of Science, Engineering, and Medicine (US) Health and Medicine Division

United States National Academies of Science, Engineering, and Medicine, Health and Medicine Division

National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division

United States National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division

An organization that initiates and conducts studies of national policy and planning for health care and health-related education and research; it also responds to requests from the federal government and other agencies for studies and advice. Was founded as the Institute of Medicine in 1970 and changed in 2016 to a Division of the Academies.


Interleukin-5
B-Cell Growth Factor-II
IL-5
BCGF-II
T-Cell-Replacing Factor
IL5
Eosinophil Differentiation Factor
Differentiation Factor, Eosinophil
T-Cell Replacing Factor

A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.


An enzyme that catalyzes the formation of 2 molecules of glutamate from glutamine plus alpha-ketoglutarate in the presence of NADPH. EC 1.4.1.13.


UDP Galactose Acetylglucosamine Galactosyltransferase

The A protein of the lactose synthase complex. In the presence of the B protein (LACTALBUMIN) specificity is changed from N-acetylglucosamine to glucose. EC 2.4.1.90.


A localized bulging or dilatation in the muscle wall of a heart (MYOCARDIUM), usually in the LEFT VENTRICLE. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are HEMATOMA caused by myocardial rupture.


Guanosine Phosphates
Guanine Nucleotides


Purinergic Receptor P2X, Ligand-Gated Ion Channel, 3

A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension, and NEUROPATHIC PAIN. The receptor comprises three P2X3 subunits. The P2X3 subunits are also associated with P2X2 RECEPTOR subunits in a heterotrimeric receptor variant.


Exotic Animals
Animals, Exotic
Exotic Pets

Animals native to a foreign country or of foreign origin or character, that are not native to the United States.


Surgical Stapler
Surgical Staplers
Stapler, Surgical
Staplers, Surgical

Fastening devices composed of steel-tantalum alloys used to close operative wounds, especially of the skin, which minimizes infection by not introducing a foreign body that would connect external and internal regions of the body. (From Segen, Current Med Talk, 1995)


A nucleic acid sequence that contains an above average number of ADENINE and THYMINE bases.


Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4

Alkylated DNA Repair Protein AlkB Homolog 4

A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1).  Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation.


DRIP Clade
Mesomycetozoea
Ichthyosporea
Ichthyophonida
Dermocystida

An order in the class MESOMYCETOZOEA whose members are pathogens of FISHES or of MAMMALS and BIRDS. Most produce uniflagellated zoospores.


A bluish-gray to gray-brown benign, melanocytic nevus found usually in the LUMBOSACRAL REGION of dark-skinned people, especially those of East Asian ancestry. It is usually congenital or appears shortly after birth, and disappears in childhood.


The application of LEECHES to the body to draw blood for therapeutic purposes. Such medicinal leeching, an ancient medical practice, is still being used in microsurgery and the treatment of venous congestion or occlusion.


Lymphoma, Large Cell, Immunoblastic
Immunoblastic Large-Cell Lymphoma
Lymphoma, Immunoblastic, Large-Cell
Lymphoma, Large-Cell, Immunoblastic
Large-Cell Immunoblastic Lymphoma
Sarcoma, Immunoblastic
Lymphoma, Immunoblastic, Large Cell
Immunoblastic Lymphosarcoma, Diffuse
Immunoblastoma

Malignant lymphoma characterized by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (LYMPHOMA, T-CELL, PERIPHERAL) recorded in both the United States and Japan.


LCMV
LCM Viruses
Lymphocytic choriomeningitis virus

The type species of ARENAVIRUS, part of the Old World Arenaviruses (ARENAVIRUSES, OLD WORLD), producing a silent infection in house and laboratory mice. In humans, infection with LCMV can be inapparent, or can present with an influenza-like illness, a benign aseptic meningitis, or a severe meningoencephalomyelitis. The virus can also infect monkeys, dogs, field mice, guinea pigs, and hamsters, the latter an epidemiologically important host.


Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. It differs from ERGOCALCIFEROL in having a single bond between C22 and C23 and lacking a methyl group at C24.


Reed-Sternberg Cells
Sternberg-Reed Cells

Large cells, usually multinucleate, whose presence is a common histologic characteristic of classical HODGKIN DISEASE.


Conception, Posthumous
Posthumous Reproduction
Posthumous Conception

Conception after the death of the male or female biological parent through techniques such as the use of gametes that have been stored during his or her lifetime or that were collected immediately after his or her death.


Constant Region, Ig
Ig Constant Regions
Immunoglobulin Constant Region
Immunoglobulin Constant Regions

The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within any class or subclass of immunoglobulin. They confer biological as well as structural functions to immunoglobulins. One each on both the light chains and the heavy chains comprises the C-terminus half of the IMMUNOGLOBULIN FAB FRAGMENT and two or three of them make up the rest of the heavy chains (all of the IMMUNOGLOBULIN FC FRAGMENT)


Barre-Lieou Syndrome
Syndrome of Barre-Lieou
Posterior Cervical Sympathetic Syndrome

A pathological condition that is characterized by a host of cranial symptoms, such as headaches, abnormal functions of the eyes and the ears, and psychological and mental disorders. This syndrome usually appears after neck injuries, inflammation, or neoplasm.


Criminal Psychology
Psychology, Criminal

The branch of psychology which investigates the psychology of crime with particular reference to the personality factors of the criminal.


Marfan Syndrome, Type I
Marfan Syndrome
Marfan's Syndrome

An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.


Phenylalanine 4-Monooxygenase
Phenylalanine Hydroxylase
Phenylalanine 4-Hydroxylase

An enzyme of the oxidoreductase class that catalyzes the formation of L-TYROSINE, dihydrobiopterin, and water from L-PHENYLALANINE, tetrahydrobiopterin, and oxygen. Deficiency of this enzyme may cause PHENYLKETONURIAS and PHENYLKETONURIA, MATERNAL. EC 1.14.16.1.


Dystrobrevin Binding Protein 1
Hermansky-Pudlak Syndrome 7 Protein
DTNBP1 Protein
Dysbindin-1
Dysbindin

A dystrophin-associated protein and component of the Biogenesis of Lysosomal Organelles Complex-1 (BLOC-1 complex) which is essential for the formation of LYSOSOME - derived organelles such as platelet dense granules and MELANOSOMES. DTNBP1 is expressed primarily in the brain and neurons, where it functions with ADAPTOR PROTEIN COMPLEX 3 to transport membrane proteins to NEURITES and nerve terminals. It also regulates the release of neurotransmitters, transport of synaptic vesicles, and localization of DOPAMINE D2 RECEPTORS. Mutations in the DTNBP1 gene are associated with Type 7 HERMANSKY-PUDLAK SYNDROME and SCHIZOPHRENIA.


Giant Cells, Foreign-Body
Foreign Body Giant Cell
Foreign Body-Type Giant Cells
Foreign Body Giant Cells

Multinucleated cells (fused macrophages), characteristic of granulomatous inflammation, which form around exogenous material in the skin. They are similar in appearance to Langhans giant cells (GIANT CELLS, LANGHANS), but foreign-body giant cells have more abundant chromatin and their nuclei are scattered in an irregular pattern in the cytoplasm.


Irrigation of the nose with saline or irrigation solutions for diagnostic or therapeutic purposes. It is used to remove irritants, allergens, or microorganisms from the nose.


Recombinant-Methionyl Human Granulocyte Colony-Stimulating Factor

A recombinant granulocyte colony-stimulating factor (G-CSF) that is used in the treatment and prevention of NEUTROPENIA, preparation and collection of blood progenitor cells, and for use in PERIPHERAL BLOOD STEM CELL TRANSPLANTATION.


Malformations Secondary to Abnormal Neuronal and Glial Proliferation or Apoptosis

Malformations of Cortical Development, Group I

Abnormal Proliferation Cortical Malformations

Malformations Due to Abnormal Neuronal and Glial Proliferation or Apoptosis

Cortical malformations secondary to abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS in NEUROGENESIS. This group includes congenital MICROCEPHALIES; MICROLISSENCEPHALIES, megalencephalies, HEMIMEGALENCEPHALIES and cortical dysplasias with balloon cells.


Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.


Forensic Anthropology
Human Identification
Anthropology, Forensic

Scientific study of human skeletal remains with the express purpose of identification. This includes establishing individual identity, trauma analysis, facial reconstruction, photographic superimposition, determination of time interval since death, and crime-scene recovery. Forensic anthropologists do not certify cause of death but provide data to assist in determination of probable cause. This is a branch of the field of physical anthropology and qualified individuals are certified by the American Board of Forensic Anthropology. (From Am J Forensic Med Pathol 1992 Jun;13(2):146)


N-substituted Glycine
N-substituted Glycines

AMINO ACIDS composed of GLYCINE substituted at the nitrogen rather than the usual carbon position, resulting in the loss of HYDROGEN BONDING donors. Polymers of these compounds are called PEPTOIDS.


Tuberculosis, Central Nervous System
Central Nervous System Tuberculosis

Tuberculosis of the brain, spinal cord, or meninges (TUBERCULOSIS, MENINGEAL), most often caused by MYCOBACTERIUM TUBERCULOSIS and rarely by MYCOBACTERIUM BOVIS. The infection may be limited to the nervous system or coexist in other organs (e.g., TUBERCULOSIS, PULMONARY). The organism tends to seed the meninges causing a diffuse meningitis and leads to the formation of TUBERCULOMA, which may occur within the brain, spinal cord, or perimeningeal spaces. Tuberculous involvement of the vertebral column (TUBERCULOSIS, SPINAL) may result in nerve root or spinal cord compression. (From Adams et al., Principles of Neurology, 6th ed, pp717-20)


Members of the phylum Arthropoda, composed of organisms having a hard, jointed exoskeleton and paired jointed legs. It includes the class INSECTS and the subclass ARACHNIDA, many species of which are important medically as parasites or as vectors of organisms capable of causing disease in man.


SNAP-25B Protein
Synaptosomal-Associated Protein 25
SNAP25 Protein
SNAP-25 Protein

A ubiquitous target SNARE protein that interacts with SYNTAXIN and SYNAPTOBREVIN. It is a core component of the machinery for intracellular MEMBRANE FUSION. The sequence contains 2 SNARE domains, one is the prototype for the Qb-SNARES, and the other is the prototype for the Qc-SNARES.


A plant genus of the family COMMELINACEAE that is used in genotoxic bioassays.


Adipose Tissue Neoplasms
Neoplasms, Adipose Tissue

Neoplasms composed of fatty tissue or connective tissue made up of fat cells in a meshwork of areolar tissue. The concept does not refer to neoplasms located in adipose tissue.


An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32.


Xanthogranulomatous Pyelonephritis
Pyelonephritis, Xanthogranulomatous

A chronic inflammatory condition of the KIDNEY resulting in diffuse renal destruction, a grossly enlarged and nonfunctioning kidney associated with NEPHROLITHIASIS and KIDNEY STONES.


An enlarged underground root or stem of some plants. It is usually rich in carbohydrates. Some, such as POTATOES, are important human FOOD. They may reproduce vegetatively from buds.


Short filamentous organism of the genus Mycoplasma, which binds firmly to the cells of the respiratory epithelium. It is one of the etiologic agents of non-viral primary atypical pneumonia in man.


Tosylphenylalanyl Chloromethyl Ketone
Chlorophenyltosylamidobutanone
TPCK
Tosylphenylalanyl Chloromethane

An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.


Gamolenic Acid
gamma-Linolenic Acid, Zinc Salt
gamma-Linolenic Acid, Potassium Salt
gamma-Linolenic Acid, Cerium Salt
gamma-Linolenic Acid
gamma-Linolenic Acid, Lithium Salt
gamma-Linolenic Acid, Indium Salt
gamma-Linolenic Acid, Ammonium Salt
gamma-Linolenic Acid, Sodium Salt

An omega-6 fatty acid produced in the body as the delta 6-desaturase metabolite of linoleic acid. It is converted to dihomo-gamma-linolenic acid, a biosynthetic precursor of monoenoic prostaglandins such as PGE1. (From Merck Index, 11th ed)


Small HSP Proteins
Heat-Shock Proteins, Small
Small Heat-Shock Proteins

A family of low molecular weight heat-shock proteins that can serve as MOLECULAR CHAPERONES.


Cannabinoid Receptor
Receptors, Cannabinoid
Cannabinoid Receptors

A class of G-protein-coupled receptors that are specific for CANNABINOIDS such as those derived from CANNABIS. They also bind a structurally distinct class of endogenous factors referred to as ENDOCANNABINOIDS. The receptor class may play a role in modulating the release of signaling molecules such as NEUROTRANSMITTERS and CYTOKINES.


Changes in the organism associated with senescence, occurring at an accelerated rate.


Proverbs and Aphorisms as Topic
Aphorisms and Proverbs as Topic
Proverbs as Topic
Fables as Topic

Works about short popular sayings effectively expressing or astutely professing general truths or useful thoughts.


A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.


Vesico-Vaginal Fistulae
Vesicovaginal Fistulae
Vesico-Vaginal Fistula
Vesicovaginal Fistula

An abnormal anatomical passage between the URINARY BLADDER and the VAGINA.


Mammary Tumor Virus, Mouse
Mammary Cancer Virus
Mouse mammary tumor virus
Mammary Tumor Viruses, Mouse
Bittner Virus

The type species of BETARETROVIRUS commonly latent in mice. It causes mammary adenocarcinoma in a genetically susceptible strain of mice when the appropriate hormonal influences operate.


Silver Russell Dwarfism
Silver-Russell Dwarfism
Russell-Silver Syndrome
Russell Silver Syndrome
Silver-Russell Syndrome

Genetically and clinically heterogeneous disorder characterized by low birth weight, postnatal growth retardation, facial dysmorphism, bilateral body asymmetry, and clinodactyly of the fifth fingers. Alterations in GENETIC IMPRINTING are involved. Hypomethylation of IGF2/H19 locus near an imprinting center region of chromosome 11p15 plays a role in a subset of Silver-Russell syndrome. Hypermethylation of the same chromosomal region, on the other hand, can cause BECKWITH-WIEDEMANN SYNDROME. Maternal UNIPARENTAL DISOMY for chromosome 7 is known to play a role in its etiology.


Advanced Glycosylation End-Product Receptors

Advanced Glycosylation Endproduct Receptors

Receptor, Advanced Glycosylation End-Products

Receptor for Advanced Glycation End Products (RAGE)

Advanced Glycosylation End Product-Specific Receptor

Advanced Glycosylation End Product Receptors

Receptor for Advanced Glycation Endproducts

RAGE (Receptor for Advanced Glycation End Products)

A single-pass transmembrane CELL SURFACE RECEPTOR that binds ADVANCED GLYCATION END PRODUCTS to mediate cellular responses to both acute and chronic vascular inflammation in conditions such as ATHEROSCLEROSIS and DIABETES MELLITUS, TYPE 2. It also binds AMYLOID BETA PEPTIDES and the ALARMINS - S100A12 and S100 CALCIUM BINDING PROTEIN BETA SUBUNIT.


The nonexpendable items used by the dentist or dental staff in the performance of professional duties. (From Boucher's Clinical Dental Terminology, 4th ed, p106)


Rimactane Rifampin Rifampicin Tubocin Rifadin Benemycin Rimactan

A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)


Histamine N-Methyltransferase
Histamine Methyltransferase

An enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to histamine, forming N-methylhistamine, the major metabolite of histamine in man. EC 2.1.1.8.


Premedication, Antibiotic
Antibiotic Prophylaxis
Antibiotic Premedication

Use of antibiotics before, during, or after a diagnostic, therapeutic, or surgical procedure to prevent infectious complications.


Cytidine 5'-Diphosphate 1,2-Diacyl-sn-Glycerol - Inositol Transferase

An enzyme that catalyzes the formation of PHOSPHATIDYLINOSITOL and CMP from CDP-DIACYLGLYCEROL and MYOINOSITOL.


Massive number of chromosomal rearrangements and shattering that occurs in cancer cells. The breakpoints are located within one chromosome or chromosome arm.


Cluster Analysis
Disease Clustering
Clustering

A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.


Social Abilities
Interpersonal Skills
Social Skills
Social Competence

Possessing the social, emotional, and intellectual skills and behaviors needed to succeed as a member of society.


An assertion that an action apparently unobjectionable in itself would set in motion a train of events leading ultimately to an undesirable outcome. (From Cambridge Dictionary of Philosophy, 1995)


Positively-charged atomic nuclei that have been stripped of their electrons. These particles have one or more units of electric charge and a mass exceeding that of the Helium-4 nucleus (alpha particle).


A plant genus of the family Hyacinthaceae (Asparagaceae). Do not confuse with water hyacinth (EICHHORNIA).


A polyaromatic hydrocarbon inducer of P4501A1 and P4501A2 cytochromes. (Proc Soc Exp Biol Med 1994 Dec:207(3):302-308)


The quality or state of being able to be bent or creased repeatedly. (From Webster, 3d ed)


A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.


Odontophobia
Dental Phobia
Dental Anxiety
Anxiety, Dental
Fear, Dental
Dental Fear
Phobia, Dental

Abnormal fear or dread of visiting the dentist for preventive care or therapy and unwarranted anxiety over dental procedures.


Radiologic Physics
Health Physics
Physics, Radiologic

The science concerned with problems of radiation protection relevant to reducing or preventing radiation exposure, and the effects of ionizing radiation on humans and their environment.


Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.


Epitopes
Antigenic Determinants
Antigenic Specificity

Sites on an antigen that interact with specific antibodies.


Stimulated T Cell Chemotactic Protein 1
SCYA22 Chemokine
Chemokine CCL22
Small Inducible Cytokine A22
CCL22 Chemokine
CC Chemokine STCP-1
Macrophage-Derived Chemokine

A CC-type chemokine with specificity for CCR4 RECEPTORS. It has activity towards TH2 CELLS and TC2 CELLS.


Physicochemical Absorption
Absorption, Physicochemical

The physical process of passing into, or being taken up or taken in by a substance.


Chlormerodrin Chlormeroprin Promeran 3-Chloromercuri-2-methoxypropylurea

A mercurial compound that has been used as a diuretic but is now superseded by more potent and less toxic drugs. The radiolabeled form has been used as a diagnostic and research tool.


A condition characterized by an abnormal increase of BILIRUBIN in the blood, which may result in JAUNDICE. Bilirubin, a breakdown product of HEME, is normally excreted in the BILE or further catabolized before excretion in the urine.


An enediyne that alkylates DNA and RNA like MITOMYCIN does, so it is cytotoxic.


The functional hereditary units of PLANTS.


NEFA
Fatty Acids, Nonesterified
Fatty Acids, Free
Free Fatty Acids

FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.


A plant genus of the family Cycadaceae, order Cycadales, class Cycadopsida, division CYCADOPHYTA of palm-like trees. It is a source of CYCASIN, the beta-D-glucoside of methylazoxymethanol.


Catheterization, Central
Central Catheterization
Catheterization, Central Venous
Venous Catheterization, Central
Central Venous Catheterization

Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein.


Adjuvant, Pharmaceutical
Adjuvant, Pharmaceutic
Pharmaceutical Adjuvant
Adjuvants, Pharmaceutical
Pharmaceutic Adjuvant
Pharmaceutical Adjuvants
Adjuvants, Pharmaceutic
Pharmaceutic Adjuvants

Agents that aid or increase the action of the principle drug (DRUG SYNERGISM) or that affect the absorption, mechanism of action, metabolism, or excretion of the primary drug (PHARMACOKINETICS) in such a way as to enhance its effects.


Trefoil Factor Family Peptides
Trefoil Factor Family Proteins
Trefoil Factors
Trefoil Peptides
Trefoil Proteins
TFF Peptides

A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents.


The provision of care involving the nursing process, to families and family members in health and illness situations. From Lippincott Manual of Nursing Practice. 6th ed.


Minichromosome Maintenance Complex Component 2

Minichromosome Maintenance Protein 2 Homolog

A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL which may provide targeting of the protein complex and an extended N-terminus which is rich in SERINE residues.


Pulmonary Hydatidoses
Pulmonary Echinococcosis
Cysts, Pulmonary Hydatid
Hydatidosis, Pulmonary
Hydatidoses, Pulmonary
Pulmonary Hydatidosis
Pulmonary Echinococcoses
Cyst, Pulmonary Hydatid
Hydatid Cysts, Pulmonary
Pulmonary Hydatid Cyst
Hydatid Cyst, Pulmonary
Echinococcoses, Pulmonary
Pulmonary Hydatid Cysts
Echinococcosis, Pulmonary

Helminth infection of the lung caused by Echinococcus granulosus or Echinococcus multilocularis.


LADA, Latent Autoimmune Diabetes in Adults

Autoimmune diabetes in adults with slowly progressive PANCREATIC BETA CELL failure and the presence of circulating autoantibodies to PANCREATIC ISLETS cell antigens.


Leukoderma Acquisitum Centrifugum of Sutton

A benign skin lesion characterized by a zone of depigmentation surrounding the nevus.


Multiparametric Magnetic Resonance Imaging

Magnetic Resonance Imaging technique that combines functional imaging techniques such as diffusion-weighted imaging (DWI), dynamic contrast-enhanced imaging and magnetic spectroscopy. This technique is widely used for active surveillance in prostate cancer imaging.


Lipotropic Factors
Lipotropic Agents
Lipocaic
Lipotropics
Lipotropic Drugs

Endogenous factors or drugs that increase the transport and metabolism of LIPIDS including the synthesis of LIPOPROTEINS by the LIVER and their uptake by extrahepatic tissues.


Abdominal Decompression
Decompression, Abdominal
Lower Body Negative Pressure
LBNP

External decompression applied to the lower body. It is used to study orthostatic intolerance and the effects of gravitation and acceleration, to produce simulated hemorrhage in physiologic research, to assess cardiovascular function, and to reduce abdominal stress during childbirth.


Auditory Evoked Potentials
Auditory Evoked Response
Evoked Potentials, Auditory

The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS.


The largest of the TARSAL BONES which is situated at the lower and back part of the FOOT, forming the HEEL.


T'ai Chi
Taiji
Tai Chi
Taijiquan
Tai Chi Chuan
Tai-ji
Tai Ji
Tai Ji Quan

One of the MARTIAL ARTS and also a form of meditative exercise using methodically slow circular stretching movements and positions of body balance.


Traditional Pulse Diagnosis
Traditional Pulse Reading

Technique used in AYURVEDIC MEDICINE, and EAST ASIAN TRADITIONAL MEDICINE, in which reading PULSE is used in the diagnosis of diseases.


Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.


DNA, Catanates
Catenated DNA
Catenanes, DNA
DNA, Catenated

CIRCULAR DNA that is interlaced together as links in a chain. It is used as an assay for the activity of DNA TOPOISOMERASES. Catenated DNA is attached loop to loop in contrast to CONCATENATED DNA which is attached end to end.


A plant genus of the family Musaceae, order Zingiberales, subclass Zingiberidae, class Liliopsida.


Delegation, Personnel
Personnel Delegation

To entrust to the care or management of another, to transfer or to assign tasks within an organizational or administrative unit or structure