Amino-Terminal Amino Acid-Acetylating Enzymes

Enzymes that catalyze the transfer of an acetyl group, usually from ACETYL COENZYME A, to the N-terminus of a peptide chain.


Laryngeal Nerve Transection
Laryngeal Neuropathy, Traumatic
Laryngeal Nerve Injuries
Laryngeal Nerve Avulsion
Laryngeal Nerve Trauma
Laryngeal Nerve Contusion

Traumatic injuries to the LARYNGEAL NERVE.


Cerebrovascular Insufficiency
Cerebrovascular Occlusion
Intracranial Vascular Disorders
Cerebrovascular Diseases
Vascular Diseases, Intracranial
Cerebrovascular Disorders
Brain Vascular Disorders

A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.


Salmon, Atlantic
Salmo salar
Atlantic Salmon

A commercially important species of SALMON in the family SALMONIDAE, order SALMONIFORMES, which occurs in the North Atlantic.


Hypovolemic Shock
Shock
Circulatory Failure
Circulatory Collapse

A pathological condition manifested by failure to perfuse or oxygenate vital organs.


H2-Oxidizing Hydrogenase
Hydrogenase
Ferredoxin Hydrogenase
Hydrogenlyase

An enzyme found in bacteria. It catalyzes the reduction of FERREDOXIN and other substances in the presence of molecular hydrogen and is involved in the electron transport of bacterial photosynthesis.


Musculoaponeurotic Fibrosarcoma Protein Family

Maf transcription factors are a family of basic-leucine zipper transcription factors that are closely related to V-MAF ONCOGENE PROTEIN. The C-MAF PROTO-ONCOGENE PROTEIN was the first mammalian Maf transcription factor identified, and now the family is known to include a variety of other Maf proteins such as MAFB TRANSCRIPTION FACTOR; MAFF TRANSCRIPTION FACTOR; MAFG TRANSCRIPTION FACTOR; and MAFK TRANSCRIPTION FACTOR.


Ardinex
N-Methylmorphine
Codeine
Isocodeine
Codeine Phosphate

An opioid analgesic related to MORPHINE but with less potent analgesic properties and mild sedative effects. It also acts centrally to suppress cough.


Solaesthin
Dichloromethane
Methylene Bichloride
Methylene Dichloride
Methylene Chloride

A chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations. Its primary use is as a solvent in manufacturing and food technology.


Antimicrobial peptides of 45-47 amino acids and typically with four disulfide bridges. They are found in PLANTS. Type-V thionins lack the C-terminal nonapeptide. This should not be confused with thionine.


Osprovit
Interpore-500
Ossopan
Calcium Hydroxyapatite
Periograf
Alveograf
Hydroxyapatite
Durapatite
Osteogen
Calcitite
Interpore-200
Ossein-Hydroxyapatite Compound
Hydroxylapatite

The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.


Runt-Related Transcription Factor 3 Protein

A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain.


Imprinting (Psychology)
Imprinting, Psychology
Imprinting, Psychological

A particular kind of learning characterized by occurrence in very early life, rapidity of acquisition, and relative insusceptibility to forgetting or extinction. Imprinted behavior includes most (or all) behavior commonly called instinctive, but imprinting is used purely descriptively.


Periodontitis, Chronic
Periodontitis, Adult
Chronic Periodontitis
Adult Periodontitis

Chronic inflammation and loss of PERIODONTIUM that is associated with the amount of DENTAL PLAQUE or DENTAL CALCULUS present. Chronic periodontitis occurs mostly in adults and was called adult periodontitis, but this disease can appear in young people.


Military Health System
Military Health Services

Services organized for the diagnosis and treatment of disease and the maintenance of health primarily of MILITARY PERSONNEL.


Botulin
Clostridium botulinum Toxins
Botulinum Toxins
Botulinum Toxin

Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.


ALLOYS designed to recover their original shape upon heating.


Dysphagia
Deglutition Disorders
Esophageal Dysphagia
Oropharyngeal Dysphagia
Swallowing Disorders

Difficulty in SWALLOWING which may result from neuromuscular disorder or mechanical obstruction. Dysphagia is classified into two distinct types: oropharyngeal dysphagia due to malfunction of the PHARYNX and UPPER ESOPHAGEAL SPHINCTER; and esophageal dysphagia due to malfunction of the ESOPHAGUS.


p31 pol Gene Product, Human Immunodeficiency Virus

p31 Integrase Protein, Human Immunodeficiency Virus

Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is a DNA nucleotidyltransferase encoded by the pol gene.


Drugs that inhibit 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE. They are commonly used to reduce the production of DIHYDROTESTOSTERONE.


Intrauterine Growth Retardation
Fetal Growth Retardation
Fetal Growth Restriction
Intrauterine Growth Restriction
Growth Retardation, Intrauterine

Failure of a FETUS to attain expected GROWTH.


Latent TGF-beta Binding Proteins
Latent TGF-beta Binding Protein 1
Latent TGF-beta Binding Protein
Latent TGF-beta Binding Protein 2
Latent TGF-beta Binding Protein 4
Latent TGF-beta Binding Protein 3

A family of secreted multidomain proteins that were originally identified by their association with the latent form of TRANSFORMING GROWTH FACTORS. They interact with a variety of EXTRACELLULAR MATRIX PROTEINS and may play a role in the regulation of TGB-beta bioavailability.


Frailty Syndrome
Frailty
Debility
Frailness

A state of increased vulnerability to stressors, following declines in function and reserves across multiple physiologic systems, characterized by MUSCLE WEAKNESS; FATIGUE; slowed motor performance; low physical activity; and unintentional weight loss.


Histamine-Sensitizing Factor
Pertussigen
Pertussis Toxin
Lymphocytosis-Promoting Factor
Islets-Activating Protein
IAP Pertussis Toxin
Islet-Activating Protein

One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose transferase activity.


Professional Delegation
Delegation, Professional

The process of assigning duties to a subordinate with lesser qualifications.


Behavior Control
Behavioral Manipulation

Manipulation of the behavior of persons or animals by biomedical, physical, psychological, or social means, including for nontherapeutic reasons.


Ethimizol Etimizol Ethymizol Ethylnorantifeine Aethimizole Ethymisole Ethimizole

A xanthine-related, putative nootropic drug.


Mandibular Injuries
Injuries, Mandibular


Ectothiorhodospira shaposhnikovii
Ectothiorhodospira vacuolata

A species of ECTOTHIORHODOSPIRA distinguished by its ability to utilize nitrate. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


Optic Neuropathy, Traumatic
Trauma, Second Cranial Nerve
Second Cranial Nerve Trauma
Optic Nerve Avulsion
Optic Nerve Contusion
Optic Nerve Trauma
Optic Nerve Injuries
Optic Nerve Transection
Second Cranial Nerve Injuries
Cranial Nerve II Injuries

Injuries to the optic nerve induced by a trauma to the face or head. These may occur with closed or penetrating injuries. Relatively minor compression of the superior aspect of orbit may also result in trauma to the optic nerve. Clinical manifestations may include visual loss, PAPILLEDEMA, and an afferent pupillary defect.


Alphadine
PVP-I
Providine
Disadine
Betaisodona
Polyvinylpyrrolidone Iodine
Povidone-Iodine
Pharmadine
Isodine
PVP-Iodine
Betadine

An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.


Triturus viridescens
Diemictylus viridescens
Notophthalmus viridescens
Newt, Red-Spotted

A species of newt in the Salamandridae family in which the larvae transform into terrestrial eft stage and later into an aquatic adult. They occur from Canada to southern United States. Viridescens refers to the greenish color often found in this species.


Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.


A congenital abnormality in which organs in the THORAX and the ABDOMEN are opposite to their normal positions (situs solitus) due to lateral transposition. Normally the STOMACH and SPLEEN are on the left, LIVER on the right, the three-lobed right lung is on the right, and the two-lobed left lung on the left. Situs inversus has a familial pattern and has been associated with a number of genes related to microtubule-associated proteins.


Sleep Walking Disorder
Somnambulism
Sleepwalking
Sleep Walking
Nocturnal Wandering

A parasomnia characterized by a partial arousal that occurs during stage IV of non-REM sleep. Affected individuals exhibit semipurposeful behaviors such as ambulation and are difficult to fully awaken. Children are primarily affected, with a peak age range of 4-6 years.


Crystalline Arthritis
Crystal Arthropathies
Crystalline Arthropathies
Crystal Arthritis

Joint disorders that are characterized by accumulation of microcrystals in and around the joint including in the SYNOVIAL FLUID. They are classified according to the chemical nature of the crystals such as CALCIUM PYROPHOSPHATE; basic CALCIUM PHOSPHATES; and monosodium urate (see URIC ACID).


Iodoacetic Acid
Sodium Iodoacetate
Monoiodoacetic Acid

A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.


A double-walled epithelial capsule that is the bulbous closed proximal end of the kidney tubular system. It surrounds the cluster of convoluted capillaries of KIDNEY GLOMERULUS and is continuous with the convoluted PROXIMAL KIDNEY TUBULE.


A plant genus of the family FABACEAE. It contains a hemagglutinin.


E2F5 Transcription Factor
E2F Transcription Factor 5 Protein
Transcription Factor E2F-5

An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F5 recruits chromatin remodeling factors indirectly to target gene promoters through RETINOBLASTOMA LIKE PROTEIN P130.


Vape
E-Cigarette Use
Vaping
Electronic Cigarette Use
E-Cig Use

SMOKING from ELECTRONIC NICOTINE DELIVERY SYSTEMS such as E-CIGARETTES.


Body Surface Mapping
Body Surface Potential Mapping

Recording of regional electrophysiological information by analysis of surface potentials to give a complete picture of the effects of the currents from the heart on the body surface. It has been applied to the diagnosis of old inferior myocardial infarction, localization of the bypass pathway in Wolff-Parkinson-White syndrome, recognition of ventricular hypertrophy, estimation of the size of a myocardial infarct, and the effects of different interventions designed to reduce infarct size. The limiting factor at present is the complexity of the recording and analysis, which requires 100 or more electrodes, sophisticated instrumentation, and dedicated personnel. (Braunwald, Heart Disease, 4th ed)


Dill Weed
Dill Plant
Dill
Anethum graveolens


A genus of the subfamily CALLICEBINAE, family PITHECIIDAE, generally comprising of five species: C. barbarabrownae; C. coimbrai; C. melanochir; C. nigrifrons; C. personatus. Titi monkeys inhibit lower levels of the forest in South America.


A flexible, tubular device that is used to carry fluids into or from a blood vessel, hollow organ, or body cavity.


Glycine Plasma Membrane Transport Proteins

Glycine Plasma Membrane Transporter Proteins

Neurotransmitter Transport Proteins, Glycine-Specific

A family of sodium chloride-dependent neurotransmitter symporters that transport the amino acid GLYCINE. They differ from GLYCINE RECEPTORS, which signal cellular responses to GLYCINE. They are located primarily on the PLASMA MEMBRANE of NEURONS; GLIAL CELLS; EPITHELIAL CELLS; and RED BLOOD CELLS where they remove inhibitory neurotransmitter glycine from the EXTRACELLULAR SPACE.


Technician, Emergency Medical
Emergency Medicine Technicians
Emergency Medical Technicians
Technicians, Emergency Medical
Paramedics, Emergency
Medical Technicians, Emergency
Medical Technician, Emergency
Emergency Medical Technician

Paramedical personnel trained to provide basic emergency care and life support under the supervision of physicians and/or nurses. These services may be carried out at the site of the emergency, in the ambulance, or in a health care institution.


Drenural Bumethanide Burinex Bumedyl Bumex PF-1593 Bumetanide Miccil Fordiuran


Paget's Disease of the Nipple and Areola

An intraductal in situ carcinoma of the breast, characterized clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells (Paget's cells).


Dupre's Syndrome
Dupre Syndrome
Pseudomeningitis
Meningitis-Like Reaction
Meningism
Meningismus

A condition characterized by neck stiffness, headache, and other symptoms suggestive of meningeal irritation, but without actual inflammation of the meninges (MENINGITIS). Spinal fluid pressure may be elevated but spinal fluid is normal. (DeJong, The Neurologic Examination, 4th ed, p673)


Betaproteobacteria
beta Proteobacteria
Proteobacteria beta

A class in the phylum PROTEOBACTERIA comprised of chemoheterotrophs and chemoautotrophs which derive nutrients from decomposition of organic material.


Muscarinic Receptor M1
Muscarinic Receptors M1
Receptor, Muscarinic M1
Receptors, Muscarinic M1

A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is found in the peripheral GANGLIA where it signals a variety of physiological functions such as GASTRIC ACID secretion and BRONCHOCONSTRICTION. This subtype of muscarinic receptor is also found in neuronal tissues including the CEREBRAL CORTEX and HIPPOCAMPUS where it mediates the process of MEMORY and LEARNING.


Submandibular Duct Calculi
Salivary Duct Calculi
Sialolithiasis, Ductal
Salivary Duct Stones
Parotid Duct Calculi

Presence of small calculi in the terminal salivary ducts (salivary sand), or stones (larger calculi) found in the larger ducts.


CYP19 Family
Cytochrome P450 Family 19
CYP19 Enzymes

A cytochrome P450 enzyme family that includes AROMATASE, which functions in the biosynthesis of ESTROGENS.


A plant species of the genus PINUS that contains isocupressic acid.


Polymyxa Plasmodiophora Plasmodiophoromycetes Plasmodiophorida Plasmodiophorids

A group of EUKARYOTES that are parasites of plants. Life cycle stages include zoospores and plasmodia.


Acyl-Coenzyme A Diacyl-glycerol Acyltransferase

An enzyme that catalyses the last step of the TRIACYLGLYCEROL synthesis reaction in which diacylglycerol is covalently joined to LONG-CHAIN ACYL COA to form triglyceride. It was formerly categorized as EC 2.3.1.124.


Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.


Endoscopic Ultrasound-Guided Fine Needle Aspiration

Conducting a fine needle biopsy with the aid of ENDOSCOPIC ULTRASONOGRAPHY.


Tuberculosis, Pleural
Pleurisy, Tuberculous

Tuberculosis of the serous membrane lining the thoracic cavity and surrounding the lungs.


Sexism
Sex Bias
Sex Discrimination
Gender Bias

Prejudice or discrimination based on gender or behavior or attitudes that foster stereotyped social roles based on gender.


Stimulatory GTP-Binding Protein, alpha Subunit

A family of heterotrimeric GTP-binding protein alpha subunits that activate ADENYLYL CYCLASES.


v-maf Oncogene Protein
maf Oncogene Protein
v-maf Protein
Oncogene Protein v-maf

An oncogene protein that was originally isolated from a spontaneous musculo-aponeurotic FIBROSARCOMA in CHICKEN and shown to be the transforming gene of the avian retrovirus AS42. It is a basic leucine zipper TRANSCRIPTION FACTOR and the founding member of the MAF TRANSCRIPTION FACTORS.


HDAC Inhibitors
Histone Deacetylase Inhibitors
Histone Deacetylase Inhibitor

Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains.


Urinary Incontinence, Stress
Urinary Stress Incontinence

Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency.


Rats, Inbred Long-Evans Cinnamon
Rats, Inbred LEC
Long-Evans Cinnamon Rats

A cinnamon-colored strain of Long-Evans rats which carries a mutation causing fulminant hepatitis and jaundice, with an associated gross accumulation of copper in the liver. This strain is a model for Wilson's Disease (see HEPATOLENTICULAR DEGENERATION).


Aspartylglucosaminidase
Aspartylglucosylamine Deaspartylase
Glycosylasparaginase
Aspartylglycosamine Amidohydrolase
Aspartylglucosamine Amidohydrolase
Aspartylglucosylaminase

An enzyme that catalyzes the conversion of N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine and water to N-acetyl-beta-D-glucosaminylamine and L-aspartate. It acts only on asparagine-oligosaccharides containing one amino acid, i.e. the ASPARAGINE has free alpha-amino and alpha-carboxyl groups. (From Enzyme Nomenclature, 1992)


Medicine, Oral
Stomatology
Oral Medicine

A branch of dentistry dealing with diseases of the oral and paraoral structures and the oral management of systemic diseases. (Hall, What is Oral Medicine, Anyway? Clinical Update: National Naval Dental Center, March 1991, p7-8)


Gastrointestinal Tuberculosis
Tuberculosis, Gastrointestinal

TUBERCULOSIS that involves any region of the GASTROINTESTINAL TRACT, mostly in the distal ILEUM and the CECUM. In most cases, MYCOBACTERIUM TUBERCULOSIS is the pathogen. Clinical features include ABDOMINAL PAIN; FEVER; and palpable mass in the ileocecal area.


Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.


Internal Strabismus
Monocular Esotropia
Esotropia
Esophoria
Secondary Esotropia
Primary Esotropia
Intermittent Esotropia
Cross-Eye
Convergent Strabismus
Esodeviation
Strabismus, Convergent
Strabismus, Internal

A form of ocular misalignment characterized by an excessive convergence of the visual axes, resulting in a "cross-eye" appearance. An example of this condition occurs when paralysis of the lateral rectus muscle causes an abnormal inward deviation of one eye on attempted gaze.


The yellow body derived from the ruptured OVARIAN FOLLICLE after OVULATION. The process of corpus luteum formation, LUTEINIZATION, is regulated by LUTEINIZING HORMONE.


Selenocysteine, DL-Isomer
3-Selenylalanine
L-Alanine, 3-selenyl-
Selenocysteine

A naturally occurring amino acid in both eukaryotic and prokaryotic organisms. It is found in tRNAs and in the catalytic site of some enzymes. The genes for glutathione peroxidase and formate dehydrogenase contain the TGA codon, which codes for this amino acid.


Retrograde Amnesia
Pre-Ictal Memory Loss
Amnesia, Retrograde
Amnesia, Pre-Ictal
Memory Loss, Retrograde

Loss of the ability to recall information that had been previously encoded in memory prior to a specified or approximate point in time. This process may be organic or psychogenic in origin. Organic forms may be associated with CRANIOCEREBRAL TRAUMA; CEREBROVASCULAR ACCIDENTS; SEIZURES; DEMENTIA; and a wide variety of other conditions that impair cerebral function. (From Adams et al., Principles of Neurology, 6th ed, pp426-9)


Education, Predental
Predental Education

Preparatory education meeting the requirements for admission to dental school.


A sulfur-containing alkyl thionitrite that is one of the NITRIC OXIDE DONORS.


Progressive Muscular Dystrophy, Oculopharyngeal Type

An autosomal dominant hereditary disease that presents in late in life and is characterized by DYSPHAGIA and progressive ptosis of the eyelids. Mutations in the gene for POLY(A)-BINDING PROTEIN II have been associated with oculopharyngeal muscular dystrophy.


Alkaloids originally isolated from the ergot fungus Claviceps purpurea (Hypocreaceae). They include compounds that are structurally related to ergoline (ERGOLINES) and ergotamine (ERGOTAMINES). Many of the ergot alkaloids act as alpha-adrenergic antagonists.


2',3'-Dideoxyinosine
Dideoxyinosine
ddI (Antiviral)
Didanosine
Videx
NSC-612049

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.


Military Psychology
Psychology, Military

The branch of applied psychology concerned with psychological aspects of selection, assignment, training, morale, etc., of Armed Forces personnel.


Cylindroma
Carcinoma, Adenoid Cystic
Adenocystic Carcinoma

Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)


Health Workforce
Manpower, Health Occupations
Health Occupations Manpower
Health Manpower
Manpower, Health

The availability of HEALTH PERSONNEL. It includes the demand and recruitment of both professional and allied health personnel, their present and future supply and distribution, and their assignment and utilization.


Evidence-Based Pharmaceutical Care
Evidence-Based Pharmacy Practice
Evidence-Based Pharmacy

The practice of pharmacy in which the pharmacist makes decisions, taking into account the best available current research evidence, the pharmacist's expertise, and the needs and preferences of the patient.


The surgical removal of the contents of the orbit. This includes the eyeball, blood vessels, muscles, fat, nerve supply, and periosteum. It should be differentiated from EYE EVISCERATION which removes the inner contents of the eye, leaving the sclera intact.


A nutritional condition produced by a deficiency of proteins in the diet, characterized by adaptive enzyme changes in the liver, increase in amino acid synthetases, and diminution of urea formation, thus conserving nitrogen and reducing its loss in the urine. Growth, immune response, repair, and production of enzymes and hormones are all impaired in severe protein deficiency. Protein deficiency may also arise in the face of adequate protein intake if the protein is of poor quality (i.e., the content of one or more amino acids is inadequate and thus becomes the limiting factor in protein utilization). (From Merck Manual, 16th ed; Harrison's Principles of Internal Medicine, 12th ed, p406)


Uterine Cervical Dysplasia
Cervix Dysplasia

Abnormal development of immature squamous EPITHELIAL CELLS of the UTERINE CERVIX, a term used to describe premalignant cytological changes in the cervical EPITHELIUM. These atypical cells do not penetrate the epithelial BASEMENT MEMBRANE.


The local implantation of tumor cells by contamination of instruments and surgical equipment during and after surgical resection, resulting in local growth of the cells and tumor formation.


Minichromosome Maintenance Complex Component 9

A minichromosome maintenance protein that forms a hexameric complex with MINICHROMSOME MAINTENANCE COMPLEX COMPONENT 8. The MCM8-MCM9 helicase complex is involved in HOMOLOGOUS RECOMBINATION REPAIR following the formation of DNA interstrand cross-links.


Infections, Actinomycetales
Actinomycetales Infections
Infections, Actinomycete
Actinomycete Infections

Infections with bacteria of the order ACTINOMYCETALES.


Substance P
SP(1-11)
Euler-Gaddum Substance P
Hypothalamic Substance P

An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.


Veterinary Service, Military
Service, Military Veterinary
Military Veterinary Service

A corps of the armed services concerned with animal medicine, the chief interest of which is the care of government-owned working dogs (as in the military police units), working horses (as in state funerals), and working military dolphins (as in undersea exploration and other activities). In the United States Army Veterinary Corps animal medicine overlaps and interconnects with biomedical research using laboratory research animals. A related activity is laboratory animal care. The Corps provides limited care for privately owned animals of military personnel through non-appropriated funds. Military service veterinarians in the United States Army must be graduates of accredited veterinary schools and must have a state license. (Telephone communication with Lt. Col. William Inskeep II, U.S. Army Veterinary Corps, October 4, 1994)


Ischemic Preconditioning, Myocardial
Myocardial Preconditioning

Exposure of myocardial tissue to brief, repeated periods of vascular occlusion in order to render the myocardium resistant to the deleterious effects of ISCHEMIA or REPERFUSION. The period of pre-exposure and the number of times the tissue is exposed to ischemia and reperfusion vary, the average being 3 to 5 minutes.


Mental Hospitals
Mental Institutions
Psychiatric Hospitals
Hospitals, Mental
Hospitals, Psychiatric

Special hospitals which provide care to the mentally ill patient.


Removal of the uterus through the vagina.


Histidine Carboxy-Lyase
Histidine Decarboxylase

An enzyme that catalyzes the decarboxylation of histidine to histamine and carbon dioxide. It requires pyridoxal phosphate in animal tissues, but not in microorganisms. EC 4.1.1.22.


Carbohydrates, Dietary
Dietary Carbohydrates

Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)


Trypanocidal Agents
Trypanosomicides
Trypanocides
Trypanosomicidal Agents
Trypanocidal Drugs

Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.


Drug Therapy, Adjuvant
Chemotherapy, Adjuvant
Adjuvant Drug Therapy

Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.


DNA Cytosine-5-Methylase
DNA (Cytosine 5) Methyltransferase
DNA (Cytosine-5-)-Methyltransferase
DNA (Cytosine-5-)-Methyltransferases

Enzymes that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the 5-position of CYTOSINE residues in DNA.


Anesthesia Recovery Period
Recovery Period, Anesthesia

The period of emergence from general anesthesia, where different elements of consciousness return at different rates.


Myotubes
Skeletal Muscle Fibers
Skeletal Myocytes
Myocytes, Skeletal
Muscle Fibers, Skeletal

Large, multinucleate single cells, either cylindrical or prismatic in shape, that form the basic unit of SKELETAL MUSCLE. They consist of MYOFIBRILS enclosed within and attached to the SARCOLEMMA. They are derived from the fusion of skeletal myoblasts (MYOBLASTS, SKELETAL) into a syncytium, followed by differentiation.


Teeth Calcification
Calcification, Tooth
Tooth Calcification

The process whereby calcium salts are deposited in the dental enamel. The process is normal in the development of bones and teeth. (Boucher's Clinical Dental Terminology, 4th ed, p43)


Kanner's Syndrome
Autism, Infantile
Autism
Autism, Early Infantile
Autistic Disorder

A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)


An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.


Signal Transducer and Activator of Transcription 2

A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.


Very toxic polypeptide isolated mainly from AMANITA phalloides (Agaricaceae) or death cup; causes fatal liver, kidney and CNS damage in mushroom poisoning; used in the study of liver damage.


Silver Plastocyanin
Plastocyanine
Plastocyanin

A copper-containing plant protein that is a fundamental link in the electron transport chain of green plants during the photosynthetic conversion of light energy by photophosphorylation into the potential energy of chemical bonds.


Painful sensations in the tongue, including a sensation of burning.


A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.


Diet, Caveman
Diet, Hunter-Gatherer
Diet, Paleo
Diet, Paleolithic
Diet, Stone Age

A nutritional plan based on the presumed diet of pre-agricultural human ancestors. It consists mainly of MEAT, EGGS, NUTS, roots and fresh VEGETABLES and FRUITS, and excludes GRAIN, LEGUMES, DAIRY PRODUCTS, and refined DIETARY SUGARS.


Gap Phase 1
G1a Phase
First Gap Phase
G1b Phase
G1 Phase

The period of the CELL CYCLE preceding DNA REPLICATION in S PHASE. Subphases of G1 include "competence" (to respond to growth factors), G1a (entry into G1), G1b (progression), and G1c (assembly). Progression through the G1 subphases is effected by limiting growth factors, nutrients, or inhibitors.


The paired caudal parts of the PROSENCEPHALON from which the THALAMUS; HYPOTHALAMUS; EPITHALAMUS; and SUBTHALAMUS are derived.


Motor Evoked Potentials
Evoked Potentials, Motor

The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.


Gas Exchange, Pulmonary
Pulmonary Gas Exchange
Exchange, Pulmonary Gas

The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.


Poland Anomaly
Poland Syndactyly
Poland Sequence
Poland Syndrome

A syndrome which is characterized by symbrachydactyly and aplasia of the sternal head of pectoralis major.


Post-Exposure Prevention
Post-Exposure Prophylaxis

The prevention of infection or disease following exposure to a pathogen.


Myocytes, Smooth Muscle
Smooth Muscle Cells

Non-striated, elongated, spindle-shaped cells found lining the digestive tract, uterus, and blood vessels. They are derived from specialized myoblasts (MYOBLASTS, SMOOTH MUSCLE).


Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.


Antibody-Dependent Cell Cytotoxicity
Cytotoxicity, Antibody-Dependent Cell
Cell Cytoxicity, Antibody-Dependent
ADCC

The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.


Urinary Bladder Neck Obstruction
Bladder Neck Obstruction
Bladder Outlet Obstruction

Blocked urine flow through the bladder neck, the narrow internal urethral opening at the base of the URINARY BLADDER. Narrowing or strictures of the URETHRA can be congenital or acquired. It is often observed in males with enlarged PROSTATE glands.


Antineoplastic Drugs, Alkylating
Alkylating Drugs, Antineoplastic
Alkylating Antineoplastics
Antineoplastics, Alkylating
Alkylating Antineoplastic Drugs
Alkylating Antineoplastic Agents
Alkylating Agents, Antineoplastic
Antineoplastic Agents, Alkylating
Antineoplastic Alkylating Agents

A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)


JAK3 Protein Tyrosine Kinase
Janus Kinase 3
JAK-3 Protein Tyrosine Kinase

A Janus kinase subtype that is predominantly expressed in hematopoietic cells. It is involved in signaling from a broad variety of CYTOKINE RECEPTORS including ones that utilize the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT.


TnpR Protein
Resolvases, Transposon
Transposon Resolvases

Recombinases that involved in the propagation of DNA TRANSPOSONS. They bind to transposon sequences found at two different sites along the same stretch of DNA and bring them into close proximity. The enzymes then catalyze the double strand cleavage, exchange of double strands and rejoining of DNA helices so that the DNA transposon is formed into a circular PLASMID.


Carbamoyl Phosphate
Carbamyl Phosphate
Dilithium Carbamyl Phosphate

The monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING).


Twist Family Bhlh Transcription Factor 2

A twist family transcription factor that is expressed in MESODERM as well as the DERMIS during mammalian EMBRYOGENESIS. It is structurally and functionally similar to TWIST-RELATED PROTEIN 1; it also regulates OSTEOGENESIS and the expression of CYTOKINES in response to INFLAMMATION.


Physician Payment Review Commission (U.S.)

United States Physician Payment Review Commission

A commission created by the Consolidated Omnibus Reconciliation Act of 1985, enacted in 1986, and given the mandate to advise Congress on Medicare-physician payment. The commission members are appointed by the U.S. Office of Technology Assessment.


Fascia, Superficial
Hypodermis
Subcutaneous Tissue
Tela Subcutanea

Loose connective tissue lying under the DERMIS, which binds SKIN loosely to subjacent tissues. It may contain a pad of ADIPOCYTES, which vary in number according to the area of the body and vary in size according to the nutritional state.


Medical Students
Medical Student
Students, Medical
Student, Medical

Individuals enrolled in a school of medicine or a formal educational program in medicine.


Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.


Visits to the patient's home by professional personnel for the purpose of diagnosis and/or treatment.


Environmental Policy
Environmental Policies
Policy, Environmental
Policies, Environmental

A course of action or principle adopted or proposed by a government, party, business, or individual that concerns human interactions with nature and natural resources.


A carbamazepine derivative that acts as a voltage-gated sodium channel blocker. It is used for the treatment of PARTIAL SEIZURES with or without secondary generalization. It is also an inducer of CYTOCHROME P-450 CYP3A4.


Surgical Procedure, Cardiac
Procedures, Cardiac Surgical
Heart Surgical Procedures
Procedure, Cardiac Surgical
Surgical Procedure, Heart
Cardiac Surgical Procedures
Surgical Procedures, Heart
Procedure, Heart Surgical
Heart Surgical Procedure
Procedures, Heart Surgical
Cardiac Surgical Procedure
Surgical Procedures, Cardiac


CYS2HIS2 Zinc Fingers
CYS2-HIS2 Zinc Finger Motifs
C2H2 Zinc Fingers
CYS2-HIS2 Zinc Fingers

A zinc finger motif of approximately 30 amino acids with the general sequence X2-Cys-X2,4-Cys-X12-His-X3,4,5-His that forms a simple beta sheet-beta sheet-alpha helix fold stabilized by zinc ions. It recognizes and binds to a variety of eukaryotic DNA sequences and is very common among sequence-specific DNA BINDING PROTEINS and TRANSCRIPTION FACTORS.


2,8-Diamino-10-Methylacridinium Chloride Mixture With 2,8-Diaminoacridine

3,6-Diamino-10-methylacridinium chloride mixt. with 3,6-acridinediamine. Fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.


Escherichia coli Proteins
E coli Proteins

Proteins obtained from ESCHERICHIA COLI.


A convulsant primarily used in experimental animals. It was formerly used to induce convulsions as a alternative to electroshock therapy.


A mitosporic fungal genus and an anamorphic form of Arthroderma. Various species attack the skin, nails, and hair.


Enzymes that catalyze the transfer of N-acetylgalactosamine from a nucleoside diphosphate N-acetylgalactosamine to an acceptor molecule which is frequently another carbohydrate. EC 2.4.1.-.


Fanconi Anemia Group G Complementing Protein

X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 9 Protein

Fanconi Anemia Complementation Group G Protein

A Fanconi anemia complementation group protein that undergoes PHOSPHORYLATION by CDC2 PROTEIN KINASE during MITOSIS. It forms a complex with other FANCONI ANEMIA PROTEINS and helps protect CELLS from DNA DAMAGE by genotoxic agents.


Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.


ATP Phosphoribosyltransferase
Phosphoribosyl-ATP Pyrophosphorylase

An enzyme that catalyzes the first step of the pathway for histidine biosynthesis in Salmonella typhimurium. ATP reacts reversibly with 5-phosphoribosyl-1-pyrophosphate to yield N-1-(5'-phosphoribosyl)-ATP and pyrophosphate. EC 2.4.2.17.


Hepatitis C Antigen
Hepatitis C Antigens
Hepatitis Non-A, Non-B Antigen

Antigens of the virions of HEPACIVIRUS, their surface, core, or other associated antigens.


Peripheral Artery Disease
Peripheral Arterial Diseases
Peripheral Arterial Disease

Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.


Withdrawing Care
Withdrawing Treatment
Cessation of Treatment
Withholding Treatment

Withholding or withdrawal of a particular treatment or treatments, often (but not necessarily) life-prolonging treatment, from a patient or from a research subject as part of a research protocol. The concept is differentiated from REFUSAL TO TREAT, where the emphasis is on the health professional's or health facility's refusal to treat a patient or group of patients when the patient or the patient's representative requests treatment. Withholding of life-prolonging treatment is usually indexed only with EUTHANASIA, PASSIVE, unless the distinction between withholding and withdrawing treatment, or the issue of withholding palliative rather than curative treatment, is discussed.


Study of the anatomy of the nervous system as a specialty or discipline.


Ferritin Repressor Protein
Iron Regulatory Protein 1
ACO1 Protein
IRP1 Protein
Aconitase 1, Soluble
IRE-BP1
IRP-1 Protein

A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its RNA binding ability and its aconitate hydrolase activity are dependent upon availability of IRON.


Infections, Rhabditida
Rhabditida Infections

Infections with nematodes of the order RHABDITIDA.


Disorder, Borderline Personality
Personality Disorder, Borderline
Borderline Personality Disorder

A personality disorder marked by a pattern of instability of interpersonal relationships, self-image, and affects, and marked impulsivity beginning by early adulthood and present in a variety of contexts. (DSM-IV)


Farnesyl Diphosphate-Geranylgeranyl Diphosphate Synthase

An enzyme that catalyzes the synthesis of geranylgeranyl diphosphate from trans, trans-farnesyl diphosphate and isopentenyl diphosphate.


Chiari-Frommel Syndrome
Frommel's Disease
Frommel Disease

A POSTPARTUM condition consists of persistent lactation (GALACTORRHEA) and AMENORRHEA in patients not BREAST FEEDING.


Udder
Mammary Glands, Animal
Animal Mammary Glands
Mammae

The bag-like organ that contains the lactating mammary gland in milk-producing animals such as CATTLE; SHEEP; SWINE; GOATS; and others.


A diagnostic radiopaque that usually occurs as the sodium salt.


Filovirus Infections
Infections, Filoviridae
Filoviridae Infections

Infections with viruses of the family FILOVIRIDAE. The infections in humans consist of a variety of clinically similar viral hemorrhagic fevers but the natural reservoir host is unknown.


Inhibitor of Differentiation Proteins
ID DNA Binding Protein Inhibitor

Inhibitor of differentiation proteins are negative regulators of BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS. They inhibit CELL DIFFERENTIATION and induce CELL PROLIFERATION by modulating different CELL CYCLE regulators.


Human Immunodeficiency Virus Gene Products

Proteins synthesized by HUMAN IMMUNODEFICIENCY VIRUSES such as the HIV-1 and HIV-2.


Atrial Myosins
Atrial Myosin
Myosins, Atrial

Myosin type II isoforms specifically found in the atrial muscle of the heart.


Psychiatry, Military
Military Psychiatry

Branch of psychiatry concerned with problems related to the prevention, diagnosis, etiology, and treatment of mental or emotional disorders of Armed Forces personnel.


Congenitally Corrected Transposition of the Great Arteries

Congenitally Corrected Transposition of the Great Vessels

A rare heart defect that occurs when the HEART VENTRICLES and attached valves, the MITRAL VALVE and the TRICUSPID VALVE are reversed so that the AORTA and the PULMONARY ARTERY are connected to the wrong ventricle. Although the heart valves and the two great arteries, the PULMONARY ARTERY and the AORTA are transposed, the blood flows to the correct place because the ventricles are also reversed and therefore corrects the transposition. It often occurs with other structural heart abnormalities.


S Amet
FO-1561
Ademetionine
SAM-e
S-Adenosylmethionine Sulfate Tosylate
S-Adenosyl-L-Methionine
Gumbaral
Samyr
S-Adenosylmethionine
AdoMet

Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)


T-Stat
Erycette
Erythromycin Phosphate
Erymax
Erythromycin
Ilotycin
Erythromycin Lactate
Erythromycin C
Erythromycin A

A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.


Lupus Erythematosus, Cutaneous, Chronic
Lupus Erythematosus, Chronic Cutaneous
Lupus Erythematosus, Discoid

A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.


Fibrous, bony, cartilaginous and osteocartilaginous fragments in a synovial joint. Major causes are osteochondritis dissecans, synovial chondromatosis, osteophytes, fractured articular surfaces and damaged menisci.


Endothelial Leukocyte Adhesion Molecule 1

Endothelial Leukocyte Adhesion Molecule-1

Cell adhesion molecule and CD antigen that mediates neutrophil, monocyte, and memory T-cell adhesion to cytokine-activated endothelial cells. E-selectin recognizes sialylated carbohydrate groups related to the Lewis X or Lewis A family.


CDK6 Protein
Cell Division Protein Kinase 6
Cyclin-Dependent Kinase 6
PLSTIRE Protein
Cdk6 Protein Kinase

Cyclin-dependent kinase 6 associates with CYCLIN D and phosphorylates RETINOBLASTOMA PROTEIN during G1 PHASE of the CELL CYCLE. It helps regulate the transition to S PHASE and its kinase activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P18.


Junin virus
Hemorrhagic Fever Virus, Argentinian

A species of ARENAVIRUS, part of the New World Arenaviruses (ARENAVIRUSES, NEW WORLD), causing Argentinian hemorrhagic fever. The disease is characterized by congestion, edema, generalized lymphadenopathy and hemorrhagic necrosis and is sometimes fatal.


Methionine-tRNA Ligase
Met-tRNA Ligase
Methionyl T RNA Synthetase
Methionyl-tRNA Synthetase

An enzyme that activates methionine with its specific transfer RNA. EC 6.1.1.10.


Fibronectin Receptor
Integrin alpha-5 beta-1
VLA-5
VLA-5 Receptors
Platelet Glycoprotein Ic-IIa
Integrin alpha5beta1
Receptors, VLA-5

An integrin found in FIBROBLASTS; PLATELETS; MONOCYTES, and LYMPHOCYTES. Integrin alpha5beta1 is the classical receptor for FIBRONECTIN, but it also functions as a receptor for LAMININ and several other EXTRACELLULAR MATRIX PROTEINS.


Birth Spacing
Pregnancy Intervals
First Birth Intervals
Birth Intervals

The time lapsed between marriage and first birth.


An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and tetrahydrofolate. It plays a role in the de novo purine biosynthetic pathway.


A family of ESOCIFORMES comprising the mudminnows. There are three genera: Dallia, Novumbra, and Umbra, with much disagreement about their taxonomic interrelations. The Umbridae are freshwater fish inhabiting parts of the Northern Hemisphere.


Spherands
Torands
Macrocyclic Compounds
Macrocycle Compounds

Cyclic compounds with a ring size of approximately 1-4 dozen atoms.


Hexastat Hexinawas Hexamethylmelamine Hexalen Altretamine Hemel

A hexamethyl-2,4,6-triamine derivative of 1,3,5-triazine.


Parasitic attack or subsistence on the skin by members of the order Phthiraptera, especially on humans by Pediculus humanus of the family Pediculidae. The hair of the head, eyelashes, and pubis is a frequent site of infestation. (From Dorland, 28th ed; Stedman, 26th ed)


Rec A Recombinases
RecA Protein
Rec A Protein

A family of recombinases initially identified in BACTERIA. They catalyze the ATP-driven exchange of DNA strands in GENETIC RECOMBINATION. The product of the reaction consists of a duplex and a displaced single-stranded loop, which has the shape of the letter D and is therefore called a D-loop structure.


Ectothiorhodospira halophila
Halorhodospira halophila

A species of Halorhodospira distinguished by its ability to grow optimally in an environment of 15-20% salinity. It was formerly called Ectothiorhodospira halophila.


Workman's Compensation
Worker's Compensation
Workers' Compensation
Workmen's Compensation

Insurance coverage providing compensation and medical benefits to individuals because of work-connected injuries or disease.


Erdheim-Chester Disease
Granulomatosis, Lipid

A rare form of non-Langerhans-cell histiocytosis (HISTIOCYTOSIS, NON-LANGERHANS-CELL) with onset in middle age. The systemic disease is characterized by infiltration of lipid-laden macrophages, multinucleated giant cells, an inflammatory infiltrate of lymphocytes and histiocytes in the bone marrow, and a generalized sclerosis of the long bones.


DMF Index
Decayed, Missing, and Filled Teeth
DMF Indexes

"Decayed, missing and filled teeth," a routinely used statistical concept in dentistry.


Viet Nam War
Vietnamese Conflict
Viet Nam Conflict
Vietnam Conflict
Second Indochina War

A conflict occurring from 1954 through 1975 within the Republic of Vietnam. It involved neighboring nations and the United States and other members of the Southeast Asia Treaty Organization.


Dithionitrobenzoic Acid
5,5'-Dithiobis(nitrobenzoate)
Ellman's Reagent
5,5'-Dithiobis(2-nitrobenzoic Acid)
DTNB

A standard reagent for the determination of reactive sulfhydryl groups by absorbance measurements. It is used primarily for the determination of sulfhydryl and disulfide groups in proteins. The color produced is due to the formation of a thio anion, 3-carboxyl-4-nitrothiophenolate.


Epithelial-Mesenchymal Transformation
Epithelial-Mesenchymal Transition

Phenotypic changes of EPITHELIAL CELLS to MESENCHYME type, which increase cell mobility critical in many developmental processes such as NEURAL TUBE development. NEOPLASM METASTASIS and DISEASE PROGRESSION may also induce this transition.


A condition characterized by the formation of CALCULI and concretions in the hollow organs or ducts of the body. They occur most often in the gallbladder, kidney, and lower urinary tract.


The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.


CT Scan, Cone-Beam
Volume Computed Tomography
Volumetric Computed Tomography
CAT Scan, Cone-Beam
Cone-Beam CT
Volumetric CT
Tomography, Volume Computed
Cone-Beam Computerized Tomography
Cone-Beam Computer-Assisted Tomography
Tomography, Cone-Beam Computed
Volume CT
Cone-Beam Computed Tomography

Computed tomography modalities which use a cone or pyramid-shaped beam of radiation.


Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.


A purine base and a fundamental unit of ADENINE NUCLEOTIDES.


Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.


Amylin Receptor Agonists
Amylin Mimetics
Amylin Receptor Agonist
Amylin Agonists

Compounds that stimulate the activity of AMYMIN RECEPTORS. Included under this heading is the endogenous form of ISLET AMYLOID POLYPEPTIDE and synthetic compounds that mimic its effect.


Coagulation Factor X
Stuart-Prower Factor
Blood Coagulation Factor X
Factor X
Autoprothrombin III
Factor Ten
Stuart Prower Factor
Stuart Factor
Factor 10

Storage-stable glycoprotein blood coagulation factor that can be activated to factor Xa by both the intrinsic and extrinsic pathways. A deficiency of factor X, sometimes called Stuart-Prower factor deficiency, may lead to a systemic coagulation disorder.


Granuloma, Foreign-Body
Foreign-Body Granuloma

Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.


A process that changes the nucleotide sequence of mRNA from that of the DNA template encoding it. Some major classes of RNA editing are as follows: 1, the conversion of cytosine to uracil in mRNA; 2, the addition of variable number of guanines at pre-determined sites; and 3, the addition and deletion of uracils, templated by guide-RNAs (RNA, GUIDE).


Antibodies, Anticardiolipin
Anticardiolipin Antibodies
Anticardiolipin Antibody

Antiphospholipid antibodies found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. The antibodies are detected by solid-phase IMMUNOASSAY employing the purified phospholipid antigen CARDIOLIPIN.


Phylloquinone Epoxide Reductase
Vitamin K Epoxide Reductases
Menadione Epoxide Reductase
Vitamin KO Reductase
Vitamin K1 Oxide Reductase
Vitamin K 1 Epoxidase
Vitamin K Epoxidase
Vitamin K Epoxide Reductase
Vitamin K 2,3-Epoxide Reductase

OXIDOREDUCTASES which mediate vitamin K metabolism by converting inactive vitamin K 2,3-epoxide to active vitamin K.


Clostridium botulinum type G
Clostridium botulinum G

Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type G. Though it has been isolated from soil, no outbreaks involving this type have been recognized.


Graft vs Leukemia Effect
Graft vs Leukemia Response
Graft-vs-Leukemia Effect
Graft-vs-Leukemia Response

Immunological rejection of leukemia cells following bone marrow transplantation.


Woman's Health Services
Services, Women's Health
Services, Woman's Health
Women's Health Services
Health Services, Woman's
Health Services, Women's

Organized services to provide health care to women. It excludes maternal care services for which MATERNAL HEALTH SERVICES is available.


Surgical Procedures, Endocrine
Procedures, Endocrine Surgical
Endocrine Surgical Procedure
Surgical Procedure, Endocrine
Procedure, Endocrine Surgical
Endocrine Surgical Procedures

Surgery performed on any endocrine gland.


A plant genus of the family ASCLEPIADACEAE. This is the true milkweed; APOCYNUM & EUPHORBIA hirta are rarely called milkweed. Asclepias asthmatica has been changed to TYLOPHORA.


Anticholinesterases
Anticholinesterase Drugs
Cholinesterase Inhibitors
Anti-Cholinesterases
Cholinesterase Inhibitors, Reversible
Anticholinesterase Agents
Cholinesterase Inhibitors, Irreversible
Acetylcholinesterase Inhibitors

Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.


Pronuclear Stage Tubal Transfer
Pronuclear Stage Transfer
PROST
Zygote Intrafallopian Transfer
ZIFT

A technique in assisted reproduction (REPRODUCTIVE TECHNIQUES, ASSISTED) consisting of hormonal stimulation of the ovaries, follicular aspiration of preovulatory oocytes, in-vitro fertilization, and intrafallopian transfer of zygotes at the pronuclear stage (before cleavage).


Superior Cervical Ganglion
Superior Cervical Ganglia

The largest and uppermost of the paravertebral sympathetic ganglia.


Coronary Thrombosis
Thrombosis, Coronary

Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.


Nucleosides containing arabinose as their sugar moiety.


Polysaccharides composed of repeating galactose units. They can consist of branched or unbranched chains in any linkages.


7-Chloro-4-nitrobenzofurazan
4-Chloro-7-nitrobenzofurazan
Nitrobenzoxadiazole Chloride
NBF-Cl
Chloronitrobenzoxadiazole
NBD Chloride

A benzofuran derivative used as a protein reagent since the terminal N-NBD-protein conjugate possesses interesting fluorescence and spectral properties. It has also been used as a covalent inhibitor of both beef heart mitochondrial ATPase and bacterial ATPase.


The presence of four sets of chromosomes. It is associated with ABNORMALITIES, MULTIPLE; and MISCARRAGES.


Formatio Reticularis Tegmenti Mesencephali

The midbrain portion of the reticular formation located in the MIDBRAIN TEGMENTUM.


Internal Fixators
Fixation Devices, Internal

Internal devices used in osteosynthesis to hold the position of the fracture in proper alignment. By applying the principles of biomedical engineering, the surgeon uses metal plates, nails, rods, etc., for the correction of skeletal defects.


Ovarian Tumor-Associated Antigen MOv18
Folate Receptor 1
Folate Receptor alpha

A subtype of GPI-anchored folate receptors that is expressed in tissues of epithelial origin. This protein is also identified as an ovarian-tumor-specific antigen.


Study of the ancient and recent human or animal past through material remains. It analyzes the physical remains of the past in pursuit of a broad and comprehensive understanding of human culture.


An AAA ATPase that binds and severs MICROTUBULES. It specifically recognizes and cuts polyglutamylated microtubules with short polyglutamate tails to promote reorganization of cellular microtubule arrays and the release of microtubules from the CENTROSOME following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in AXONS; SPINDLE APPARATUS; and CILIA. Mutations in the spastin gene (SPAST) are associated with type 4 of HEREDITARY SPASTIC PARAPLEGIA.


Nursing Education, Baccalaureate
Education, Nursing, Baccalaureate
Baccalaureate Nursing Education
External Degree Programs, Nursing

A four-year program in nursing education in a college or university leading to a B.S.N. (Bachelor of Science in Nursing). Graduates are eligible for state examination for licensure as RN (Registered Nurse).


Hexokinase
Hexokinase II
Hexokinase A
Hexokinase D

An enzyme that catalyzes the conversion of ATP and a D-hexose to ADP and a D-hexose 6-phosphate. D-Glucose, D-mannose, D-fructose, sorbitol, and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase. (From Enzyme Nomenclature, 1992) EC 2.7.1.1.


sncRNAs
Small Non-Protein-Coding RNA
Small Non-Coding RNA
Small Untranslated RNA
Small Non-Messenger RNA
Short Noncoding RNA
RNA, Small Untranslated
Small Noncoding RNA
sncRNA

Short RNA, about 200 base pairs in length or shorter, that does not code for protein.


Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists.


Infections, Pasteurellaceae
Pasteurellaceae Infections

Infections with bacteria of the family PASTEURELLACEAE.


Mitogen-Activated Protein Kinase Kinase Kinase 4

A 180-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 4 and MAP KINASE KINASE 6.


An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.


Peptide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.


Intraoperative Monitoring
Monitoring, Intraoperative

The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs).


TNF Receptor-Associated Factor 5
TNF Receptor-Associated Protein 5
TRAF5

A signal transducing tumor necrosis factor receptor associated factor that mediates signaling from CD27 ANTIGENS; CD40 ANTIGENS; and the LYMPHOTOXIN BETA RECEPTOR. It is involved in regulation of NF-KAPPA B signaling.


A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.


Construction Materials
Building Materials


Nurses who provide nursing care in countries other than the ones in which they received their training.


MK 990
Rafoxanide
Flukanide
Ranide
Disalan
Rafoxanid

Veterinary anthelmintic for grazing animals; used to treat fluke, hookworm and other infestations.


Medicine, Tibetan Traditional
Tibetan Traditional Medicine
Tibetan Medicine, Traditional
Tibetan Medicine
Traditional Medicine, Tibetan

A system of traditional medicine which is based on the beliefs and practices of the Tibetan culture.


Classification, Book
Book Classification

A general term covering bibliographical and bibliothecal classifications. It mostly refers to library CLASSIFICATION for arrangement of books and documents on the shelves. (Harrod's Librarians' Glossary, 7th ed, p85)


Fascitis, Necrotizing
Fasciitis, Necrotizing

A fulminating bacterial infection of the deep layers of the skin and FASCIA. It can be caused by many different organisms, with STREPTOCOCCUS PYOGENES being the most common.


A group of cytochromes with covalent thioether linkages between either or both of the vinyl side chains of protoheme and the protein. (Enzyme Nomenclature, 1992, p539)


Protein-Arginine Deimination
Citrullination
Peptidylarginine Deimination
Protein Deimination

Conversion of ARGININE residues in proteins into CITRULLINE residues by PROTEIN-ARGININE DEIMINASES.


Antigens, CD321
Junctional Adhesion Molecule A
Receptors, F11
CD321 Antigen
F11 Receptor

A cell adhesion protein that is found within TIGHT JUNCTIONS of ENDOTHELIAL CELLS and on the CELL MEMBRANE surface of circulating PLATELETS.


Inosine 5'-(tetrahydrogen triphosphate). An inosine nucleotide containing three phosphate groups esterified to the sugar moiety. Synonym: IRPPP.


Coping Skills
Adaptation, Psychologic
Behavior, Adaptive
Psychological Adaptation
Adaptation, Psychological
Coping Behavior

A state of harmony between internal needs and external demands and the processes used in achieving this condition. (From APA Thesaurus of Psychological Index Terms, 8th ed)


Receptor Down-Regulation
Downregulation
Down-Regulation (Physiology)
Down-Regulation

A negative regulatory process that decreases ligand-receptor interactions. Reduction in receptor binding after ligand exposure can result from the internalization of ligand-receptor complex, an increase in receptor degradation, and/or a decrease in gene expression resulting in a decrease in receptor biosynthesis.


A subclass of enzymes of the transferase class that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Most of these enzymes are pyridoxyl phosphate proteins. (Dorland, 28th ed) EC 2.6.1.


Multidrug Resistance, Fungal
Multiple Antifungal Drug Resistance
Drug Resistance, Multiple, Fungal

The ability of fungi to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance phenotype may be attributed to multiple gene mutations.


Cryoultramicrotomy
Cryosectioning
Freeze Sectioning

The technique of using a cryostat or freezing microtome, in which the temperature is regulated to -20 degrees Celsius, to cut ultrathin frozen sections for microscopic (usually, electron microscopic) examination.


Ether-A-Go-Go Related Potassium Channels

A family of voltage-gated potassium channels that are characterized by long N-terminal and C-terminal intracellular tails. They are named from the Drosophila protein whose mutation causes abnormal leg shaking under ether anesthesia. Their activation kinetics are dependent on extracellular MAGNESIUM and PROTON concentration.


Libraries, Virtual
Digital Libraries
Libraries, Digital

Libraries in which a major proportion of the resources are available in machine-readable format, rather than on paper or MICROFORM.


Central Nervous System Diseases
Central Nervous System Disorders
CNS Diseases

Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.


Cyclophilin A
Peptidyl-Prolyl cis-trans Isomerase A

A 17-KDa cytoplasmic PEPTIDYLPROLYL ISOMERASE involved in immunoregulation. It is a member of the cyclophilin family of proteins that binds to CYCLOSPORINE.


Catabolite Regulator Protein
Gene Activator, Catabolic
Regulator Protein, Catabolite
Catabolic Gene Activator
cAMP Receptor Protein
Catabolite Activator Proteins
Activator, Catabolic Gene
Gene Activators, Catabolic
Cyclic AMP Receptor Proteins
Catabolite Gene Activator Proteins
Activator Proteins, Catabolite
Proteins, Catabolite Activator
Catabolite Regulator Proteins
cAMP Receptor Proteins
Activators, Catabolic Gene
Protein, Catabolite Regulator
Proteins, Catabolite Regulator
Catabolic Gene Activators
Activator Protein, Catabolite
Catabolite Gene Activator Protein
Regulator Proteins, Catabolite
Catabolite Activator Protein
Cyclic AMP Receptor Protein
Protein, Catabolite Activator

A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.


Antibodies, Allotypic
Immunoglobulin Allotypes
Ig Allotypes
Allotypes, Immunoglobulin
Allotypic Antibodies

Allelic variants of the immunoglobulin light chains (IMMUNOGLOBULIN LIGHT CHAINS) or heavy chains (IMMUNOGLOBULIN HEAVY CHAINS) encoded by ALLELES of IMMUNOGLOBULIN GENES.


Neuropilins are 140-kDa vertebrate cell surface receptors that bind neuronal guidance molecules during neural development and axonal outgrowth, and modulate VEGF-mediated angiogenesis. NEUROPILIN-1 and NEUROPILIN-2 differ in their binding specificities, and are distributed complementarily in regions of the developing nervous system. Neuropilins are receptors for secreted CLASS 3 SEMAPHORINS as well as for vascular endothelial growth factors, and may form hetero- or homodimers. They may also interact synergistically with plexins and with VEGF RECEPTORS to form receptor complexes with distinct affinities and specificities. Neuropilin binding specificity is determined by CUB and coagulation-factor-like domains in the extracellular portion of the molecule, while a MAM domain is essential for SIGNAL TRANSDUCTION.


Sociometric Technics
Sociometric Techniques

Methods for quantitatively assessing and measuring interpersonal and group relationships.


Protease Inhibitor Leuserpin 2
Leuserpin 2
Serpin D1
Heparin Cofactor II
Heparin Co-Factor II
Heparin Cofactor 2

A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily.


Spiral Cone-Beam Computerized Tomography

Spiral Cone-Beam Computer-Assisted Tomography

Modality of computed tomography in which the patient is irradiated in a spiral path around the body with a cone or pyramid-shaped beam.


Familial Mediterranean Fever, Autosomal Recessive

A group of HEREDITARY AUTOINFLAMMATION DISEASES, characterized by recurrent fever, abdominal pain, headache, rash, PLEURISY; and ARTHRITIS. ORCHITIS; benign MENINGITIS; and AMYLOIDOSIS may also occur. Homozygous or compound heterozygous mutations in marenostrin gene result in autosomal recessive transmission; simple heterozygous, autosomal dominant form of the disease.


Economic aspects of the dental profession and dental care.


Alien Hand Syndrome
Anarchic Hand Syndrome

An apraxia characterized by the affected limb having involuntary, autonomous, and purposeful behaviors that are perceived as being controlled by an external force. Often the affected limb interferes with the actions of the normal limb. Symptoms develop from lesions in the CORPUS CALLOSUM or medial frontal cortex, stroke, infarction, and neurodegenerative diseases (e.g., CREUTZFELDT-JAKOB SYNDROME, corticobasal degeneration).


EphA2 Receptor
Mammary-Derived Tyrosine Kinase 2
EphA2 Protein
Receptor, EphA2
Epithelial Cell Kinase Protein
EphA2 Receptor Tyrosine Kinase
EphA2-Tyrosine Kinase

An Eph family receptor found abundantly in tissues of epithelial origin. It is expressed in a diverse array of tissues during embryonic development, suggesting that it may play a role in embryogenesis. In adult tissues high levels of the receptor are expressed in the LUNG; SKIN; SMALL INTESTINE and OVARY.


Poly A-Binding Proteins
Poly(A)-Binding Protein
Poly A-Binding Protein
Poly(A)+ mRNA Binding Protein
Poly(A)-Binding Proteins

Proteins that bind to the 3' polyadenylated region of MRNA. When complexed with RNA the proteins serve an array of functions such as stabilizing the 3' end of RNA, promoting poly(A) synthesis and stimulating mRNA translation.


Children, Adopted
Adopted, Children
Child, Adopted

Individual who becomes a child of a family by means of legal action.


Peptide Initiation Factor-1, Prokaryotic

The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD. It binds near the A-site of the 30S subunit of RIBOSOMES and may play a role in preventing premature addition of aminoacyl-tRNA-linked PEPTIDE ELONGATION FACTOR TU to the ribosome during the initiation of a peptide chain (PEPTIDE CHAIN INITIATION, TRANSLATIONAL).


Bed Sores
Pressure Sore
Decubitus Ulcer
Pressure Ulcer
Bedsore

An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.


An enzyme which catalyzes the hydrolysis of LACTOSE to D-GALACTOSE and D-GLUCOSE. Defects in the enzyme cause LACTOSE INTOLERANCE.


beta3-Adrenergic Antagonists
Adrenergic beta-3 Receptor Blockers
beta-3 Adrenergic Blocking Agents
Adrenergic beta-3 Antagonists
Adrenergic beta-3 Receptor Antagonists

Drugs that bind to and block the activation of ADRENERGIC BETA-3 RECEPTORS.


Oximes
Aldoximes
Ketoximes
Hydroxyimino Compounds


E2F Transcription Factor 3 Protein
E2F3a Transcription Factor
E2F3 Transcription Factor
Transcription Factor E2F-3
E2F3b Transcription Factor

An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F3 regulates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis.


Multiple Idiopathic Pigmented Hemangiosarcoma

A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.


Polycyclic aromatic hydrocarbon found in tobacco smoke that is a potent carcinogen.


GLP-1R Receptor
GLP1R Receptor
Glucagon-Like Peptide-1 Receptor
GLP-1 Receptor
GLP1R Protein

A receptor for GLUCAGON-LIKE PEPTIDE 1 (GLP-1) expressed primarily on the surface of beta and ductal exocrine cells of the pancreas, as well as cells of other tissues. GLP-1 acts through GLP-1R to potentiate signaling in pancreatic cells in response to glucose-stimulated insulin secretion (GSIS).


Bioindicator
Environmental Biomarkers
Biological Indicator

A factor associated with the well-being of living organisms that is used as a measure of environmental change and or influence. For example, aldehyde dehydrogenase expression in earthworm tissue is used as an indication of heavy metal pollution in soils. Distinguish from BIOMARKERS.


The elements OXYGEN; POLONIUM; SELENIUM; SULFUR; and TELLURIUM; that form group 16 (formerly group VI) of the periodic table.


Universal Health Insurance
Universal Coverage

Health insurance coverage for all persons in a state or country, rather than for some subset of the population. It may extend to the unemployed as well as to the employed; to aliens as well as to citizens; for pre-existing conditions as well as for current illnesses; for mental as well as for physical conditions.


Lymphocyte Stimulatory Loci, Minor
Mls Loci
Minor Lymphocyte Stimulatory Loci
M Locus

Genetic loci responsible for the encoding of minor lymphocyte stimulatory antigens. There are at least two unlinked loci (in the mouse) and they appear to be separate from the MAJOR HISTOCOMPATIBILITY COMPLEX and MINOR HISTOCOMPATIBILITY LOCI. The mouse mammary tumor virus (see MAMMARY TUMOR VIRUS, MOUSE) has the ability to integrate into these loci. The antigens induce strong T-cell proliferative responses in mixed lymphocyte reactions.


Cyclic S Oxides
Cyclic S-Oxides
Heterocyclic S-Oxides


Acroosteolysis Syndrome
Acro-Osteolysis
Acroosteolysis
Acro-Osteolysis Syndromes

A condition with congenital and acquired forms causing recurrent ulcers in the fingers and toes. The congenital form exhibits autosomal dominant inheritance; the acquired form is found in workers who handle VINYL CHLORIDE. When acro-osteolysis is accompanied by generalized OSTEOPOROSIS and skull deformations, it is called HAJDU-CHENEY SYNDROME.


Ventricular Function, Left
Left Ventricular Function

The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.


The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)


An industrial solvent which causes nervous system degeneration. MBK is an acronym often used to refer to it.


The making of a radiograph of an object or tissue by recording on a photographic plate the radiation emitted by radioactive material within the object. (Dorland, 27th ed)


A pattern recognition receptor that forms heterodimers with TLR2 RECEPTOR. The complex interacts with a variety of ligands including LIPOPROTEINS from MYCOPLASMA.


Allogeneic Transplantation
Transplantation, Allogeneic
Allografting
Homografting
Transplantation, Homologous
Homologous Transplantation
Allogeneic Grafting

Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.


Enzymes that catalyze the cleavage of a carbon-sulfur bond by means other than hydrolysis or oxidation. EC 4.4.


CAIX Protein
Carbonic Anhydrase IX
Carbonic Anhydrase 9

A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA.


Cartilage, Epiphyseal
Epiphyseal Plate
Epiphyseal Cartilage
Growth Plate

The area between the EPIPHYSIS and the DIAPHYSIS within which bone growth occurs.


Heteroduplex DNA
Nucleic Acid Heteroduplexes
Heteroduplexes, Nucleic Acid

Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.


ATP Binding Cassette Transporter, Sub-Family G, Member 5

ATP Binding Cassette Transporter, Subfamily G, Member 5

ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY G protein that functions as a heterodimer with ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY G, MEMBER 8 in the selective transport of DIETARY CHOLESTEROL and PHYTOSTEROLS into and export out of ENTEROCYTES. It also functions in selective sterol excretion by the liver into bile.


Killer Cell Immunoglobulin-Like Receptor 2DL3

A KIR receptor that has specificity for HLA-C ANTIGEN. It is an inhibitory receptor that contains D1 and D2 extracellular immunoglobulin-like domains and a long cytoplasmic tail. It is similar in structure and function to the KIR2DL2 RECEPTORS and the KIR2DL3 RECEPTORS.


A genus of FLAVIVIRIDAE containing several subgroups and many species. Most are arboviruses transmitted by mosquitoes or ticks. The type species is YELLOW FEVER VIRUS.


Trigger Thumb
Trigger Digits
Trigger Finger Disorder
Flexor Tendon Entrapment
Snapping Finger

A painful disability in the hand affecting the finger or thumb. It is caused by mechanical impingement of the digital flexor tendons as they pass through a narrowed retinacular pulley at the level of the metacarpal head. Thickening of the sheath and fibrocartilaginous metaplasia can occur, and nodules can form. (From Green's Operative Hand Surgery, 5th ed, p2137-58).


Acne Inversa
Suppurative Hidradenitides
Hidradenitides, Suppurative
Hidradenitis Suppurativa
Suppurative Hidradenitis
Hidradenitis, Suppurative

A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident.


Chemokine CCL24
Eotaxin-2
CCL24 Chemokine
Myeloid Progenitor Inhibitory Factor 2

A CC-type chemokine with specificity for CCR3 RECEPTORS. It is a chemoattractant for EOSINOPHILS.


A genus of the family Lorisidae having four species which inhabit the forests and bush regions of Africa south of the Sahara and some nearby islands. The four species are G. alleni, G. crassicaudatus, G. demidovii, and G. senegalensis. There is another genus, Euoticus, containing two species which some authors have included in the Galago genus.


Fanconi Anemia Group A Complementing Protein

Fanconi Anemia Complementation Group A Protein

A Fanconi anemia complementation group protein that is the most commonly mutated protein in FANCONI ANEMIA. It undergoes PHOSPHORYLATION by PROTEIN KINASE B and forms a complex with FANCC PROTEIN in the CELL NUCLEUS.


Epithelioma, Basal Cell
Ulcer, Rodent
Carcinoma, Basal Cell, Pigmented
Rodent Ulcer
Carcinoma, Basal Cell

A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)


Homogentisate 1,2-Dioxygenase
Homogentisic Acid Oxidase
Homogentisate Oxygenase
Homogentisate Dioxygenase
Homogentisate Oxidase

A mononuclear Fe(II)-dependent oxygenase, this enzyme catalyzes the conversion of homogentisate to 4-maleylacetoacetate, the third step in the pathway for the catabolism of TYROSINE. Deficiency in the enzyme causes ALKAPTONURIA, an autosomal recessive disorder, characterized by homogentisic aciduria, OCHRONOSIS and ARTHRITIS. This enzyme was formerly characterized as EC 1.13.1.5 and EC 1.99.2.5.


National Health Planning Information Center (U.S.)

National Health Planning Information Center, U.S.

United States National Health Planning Information Center

A center in the HEALTH RESOURCES ADMINISTRATION Division of Planning Methods and Technology which provides access to current information on health planning and resources development.


Dopamine D4 Receptor
Dopamine D4 Receptors
Receptors, Dopamine D4
Receptor, Dopamine D4

A subtype of dopamine D2 receptors that has high affinity for the antipsychotic CLOZAPINE.


Antiplatyhelmintic Agents
Antiplatyhelmintics
Antiplatyhelmintic Drugs

Agents used to treat cestode, trematode, or other flatworm infestations in man or animals.


Applied Kinesiology
Kinesiology, Applied

The study of muscles and the movement of the human body. In holistic medicine it is the balance of movement and the interaction of a person's energy systems. Applied kinesiology is the name given by its inventor, Dr. George Goodheart, to the system of applying muscle testing diagnostically and therapeutically to different aspects of health care. (Thorsons Introductory Guide to Kinesiology, 1992, p13)


Cytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate.


Anaplasmataceae Infections
Haemobartonellosis
Infections, Anaplasmataceae

Infections with bacteria of the family ANAPLASMATACEAE.


Adjustment of the eyes under conditions of low light. The sensitivity of the eye to light is increased during dark adaptation.


1,3-beta-Glucanase
Exo-1,3 beta-D-Glucosidase
Glucan 1,3-beta-Glucosidase
Beta-1,3-Glucanase Type II

An exocellulase with specificity for 1,3-beta-D-glucasidic linkages. It catalyzes hydrolysis of beta-D-glucose units from the non-reducing ends of 1,3-beta-D-glucans, releasing GLUCOSE.


Targeted Gene Correction
Oligonucleotide-Directed Gene Repair
Targeted Gene Repair
Targeted Mutation Repair

A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.


Fowl Plague
Influenza in Birds
Avian Influenza
Avian Flu
Influenza, Avian

Infection of domestic and wild fowl and other BIRDS with INFLUENZA A VIRUS. Avian influenza usually does not sicken birds, but can be highly pathogenic and fatal in domestic POULTRY.


Adhesion Plaques
Focal Contacts
Cell-Matrix Adherens Junctions
Focal Adhesions

An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.


Steroids that bring about MOLTING or ecdysis in insects. Ecdysteroids include the endogenous insect hormones (ECDYSONE and ECDYSTERONE) and the insect-molting hormones found in plants, the phytoecdysteroids. Phytoecdysteroids are natural insecticides.


Septo-Optic Dysplasia with Growth Hormone Deficiency

A condition resulting from congenital malformations involving the brain. The syndrome of septo-optic dysplasia combines hypoplasia or agenesis of the SEPTUM PELLUCIDUM and the OPTIC NERVE. The extent of the abnormalities can vary. Septo-optic dysplasia is often associated with abnormalities of the hypothalamic and other diencephalic structures, and HYPOPITUITARISM.


Drug Pulse Therapy
Pulse Therapy, Drug
Pulse Drug Therapy

Administration of high doses of pharmaceuticals over short periods of time.


Multimodal Treatment
Therapy, Combined Modality
Combined Modality Therapy

The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.


Adipose Tissue, Beige
Brite Fat
Brite Adipose Tissue
Beige Brite Adipose Tissue
Beige Brite Fat
Beige Fat
Adipose Tissue, Brite
Beige Adipose Tissue

Brown fat-like adipose tissue that develops in WHITE ADIPOSE TISSUE from non-MYOGENIC REGULATORY FACTOR 5 expressing cell lineage.


Attrition, Dental
Occlusal Wear
Tooth Attrition
Dental Attrition

The wearing away of a tooth as a result of tooth-to-tooth contact, as in mastication, occurring only on the occlusal, incisal, and proximal surfaces. It is chiefly associated with aging. It is differentiated from TOOTH ABRASION (the pathologic wearing away of the tooth substance by friction, as brushing, bruxism, clenching, and other mechanical causes) and from TOOTH EROSION (the loss of substance caused by chemical action without bacterial action). (Jablonski, Dictionary of Dentistry, 1992, p86)


Embolism, Air
Embolism, Gas
Air Embolism

Blocking of a blood vessel by air bubbles that enter the circulatory system, usually after TRAUMA; surgical procedures, or changes in atmospheric pressure.


Actin Filament Capping Proteins
Actin Capping Proteins
Actin-Capping Proteins
Capping Protein, Actin

Actin capping proteins are cytoskeletal proteins that bind to the ends of ACTIN FILAMENTS to regulate actin polymerization.


Antifibrinolytic hemostatic used in severe hemorrhage.


Mitochondrial Transmembrane Permeability-Driven Cell Death

Mitochondrial Transmembrane Permeability-Driven Necrosis

A form of regulated cell death that is initiated by specific perturbations of the intracellular microenvironment such as severe OXIDATIVE STRESS and cytosolic CALCIUM overload, which result in osmotic breakdown of the MITOCHONDRIAL MEMBRANES.


Tracheomalacia
Chondromalacia of Trachea

A congenital or acquired condition of underdeveloped or degeneration of CARTILAGE in the TRACHEA. This results in a floppy tracheal wall making patency difficult to maintain. It is characterized by wheezing and difficult breathing.


Egypt 101 virus
Kunjin virus
West Nile virus

A subtype of WEST NILE VIRUS found in Africa, Europe, the Middle East, west and central Asia, and Oceania.


Drug Administration, Buccal
Administration, Buccal
Buccal Drug Administration
Buccal Administration

Administration of a soluble dosage form between the cheek and gingiva. It may involve direct application of a drug onto the buccal mucosa, as by painting or spraying.


Aspiration, Mechanical
Suction
Drainage, Suction

The removal of secretions, gas or fluid from hollow or tubular organs or cavities by means of a tube and a device that acts on negative pressure.


Nurse Midwives
Nurse-Midwife
Nurse-Midwives

Professional nurses who have received postgraduate training in MIDWIFERY.


Nucleocapsid Protein
Viral N Protein
Nucleocapsid Proteins

Viral proteins found in either the NUCLEOCAPSID or the viral core (VIRAL CORE PROTEINS).


(T-4)-Osmium oxide (OsO4). A highly toxic and volatile oxide of osmium used in industry as an oxidizing agent. It is also used as a histological fixative and stain and as a synovectomy agent in arthritic joints. Its vapor can cause eye, skin, and lung damage.


Mycobacterium haemophilum
Mycobacterium hemophilum

A species of gram-positive, aerobic bacteria that causes granulomatous or ulcerating skin lesions in immunosuppressed persons. This organism owes its name to its requirement for growth of high levels of iron, conveniently supplied as blood, heme, or ferric ammonium citrate.


Lenses, Contact, Hydrophilic
Contact Lenses, Hydrophilic
Hydrophilic Contact Lens
Soft Contact Lens
Soft Contact Lenses

Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.


Collagen-Degrading Enzyme
Collagenases
Collagenase
Collagen Peptidase

Enzymes that catalyze the degradation of collagen by acting on the peptide bonds.


The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept.


Adrenomedullin Receptors
Adrenomedullin Receptor
Receptors, Adrenomedullin

G-protein-coupled cell surface receptors for ADRENOMEDULLIN. They are formed by the heterodimerization of CALCITONIN RECEPTOR-LIKE PROTEIN and either RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 or RECEPTOR ACTIVITY-MODIFYING PROTEIN 3.


An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)


Human Coronavirus NL63
HCoV-NL63
Coronavirus NL63, Human

A species in the genus CORONAVIRUS causing upper and lower RESPIRATORY TRACT INFECTIONS. It shares the receptor used by the SARS VIRUS.


The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.


Arachidonic Acid 12-Lipoxygenase
Arachidonate 12-Lipoxygenase
12-Lipoxygenase

An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.


Pharmaceutic Solutions
Solutions, Pharmaceutical
Pharmaceutical Solutions

Homogeneous liquid preparations that contain one or more chemical substances dissolved, i.e., molecularly dispersed, in a suitable solvent or mixture of mutually miscible solvents. For reasons of their ingredients, method of preparation, or use, they do not fall into another group of products.


A type of viscous polysaccharide that is secreted from PLANTS. It has natural properties that are useful in the formulation of ADHESIVES.


Cyclic-AMP-Dependent Protein Kinase RIIalpha Subunit

cAMP-Dependent Protein Kinase type II-alpha Regulatory Subunit

cAMP-Dependent Protein Kinase, Type 2alpha-Regulatory Subunit

Regulatory Subunit RIIalpha, Cyclic-AMP-Dependent Protein Kinase

Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit

A type II cAMP-dependent protein kinase regulatory subunit that plays a role in confering CYCLIC AMP activation of protein kinase activity. It has a higher affinity for cAMP than that of the CYCLIC-AMP-DEPENDENT PROTEIN KINASE RIIBETA SUBUNIT. Binding of this subunit by A KINASE ANCHOR PROTEINS may play a role in the cellular localization of type II protein kinase A.


Cervical Cerclage
Cerclage of Uterine Cervix
Cerclage, Cervical
Cerclage of Cervix

The surgical closure of the incompetent cervix uteri with suture material.


A genus of gram-positive, aerobic bacteria. Most species are free-living in soil and water, but the major habitat for some is the diseased tissue of warm-blooded hosts.


Warmup Exercise
Warm-Up Exercise
Warming-Up Exercise

Physical activities done to prepare the body for more intense physical activities.


Joint Commission on Accreditation of Healthcare Organizations

Joint Commission on Accreditation, Health Care Organizations

Joint Commission of Accreditation, Health Care Organizations

Joint Commission on Accreditation of Health Care Organizations

Joint Commission on Accreditation of Hospitals

Joint Commission on Accreditation, Healthcare Organizations

A private, voluntary, not-for-profit organization which establishes standards for the operation of health facilities and services, conducts surveys, and awards accreditation.


Infections, Protozoan
Histomoniasis
Protozoan Infections

Infections with unicellular organisms formerly members of the subkingdom Protozoa.


Superoxide Anion
Superoxides
Superoxide
Superoxide Radical

Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.


Data Warehouse
Data Mart
Data Warehousing
Datawarehousing
Datawarehouse
Enterprise Data Warehouse

A system for storing electronic data derived from various sources.


Protein Translation
Protein Biosynthesis
Genetic Translation
mRNA Translation
Peptide Biosynthesis, Ribosomal
Protein Synthesis, Ribosomal
Protein Biosynthesis, Ribosomal
Ribosomal Peptide Biosynthesis
Translation, Genetic

The biosynthesis of PEPTIDES and PROTEINS on RIBOSOMES, directed by MESSENGER RNA, via TRANSFER RNA that is charged with standard proteinogenic AMINO ACIDS.


A layer of vascularized connective tissue underneath the EPIDERMIS. The surface of the dermis contains innervated papillae. Embedded in or beneath the dermis are SWEAT GLANDS; HAIR FOLLICLES; and SEBACEOUS GLANDS.


Bumetanide-Sensitive Sodium Potassium Chloride Cotransporter 2

Solute Carrier Family 12 (Sodium Potassium Chloride Transporters), Member 2

Sodium-Potassium-Chloride Cotransporter 1 Protein

Na-K-Cl transporter ubiquitously expressed. It plays a key role in salt secretion in epithelial cells and cell volume regulation in nonepithelial cells.


Second-Look Surgery
Surgery, Second-Look

A followup operation to examine the outcome of the previous surgery and other treatments, such as chemotherapy or radiation therapy.


Phenylsulfapyrazole Sulphaphenazole Sulfaphenylpyrazol Sulfaphenazole


Twist Family Transcription Factors
Twist Transcription Factor Family
Twist Transcription Factors

A  highly-conserved family of basic helix-loop-helix (bHLH) transcription factors.  They function as dimers with other bHLH proteins and bind E-BOX ELEMENTS to control gene expression during EMBRYOGENESIS and the EPITHELIAL-MESENCHYMAL TRANSITION.


Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)


An NAD-dependent enzyme that catalyzes the oxidation of acyl-[acyl-carrier protein] to trans-2,3-dehydroacyl-[acyl-carrier protein]. It has a preference for acyl groups with a carbon chain length between 4 to 16.


A type of impedance plethysmography in which bioelectrical impedance is measured between electrodes positioned around the neck and around the lower thorax. It is used principally to calculate stroke volume and cardiac volume, but it is also related to myocardial contractility, thoracic fluid content, and circulation to the extremities.


HHV-7
Human Herpesvirus 7
Herpesvirus 7, Human

A species in the genus ROSEOLOVIRUS, of the family HERPESVIRIDAE. It was isolated from activated, CD4-positive T-lymphocytes taken from the blood of a healthy human.


A very complex, but reproducible mixture of at least 177 C10 polychloro derivatives, having an approximate overall empirical formula of C10-H10-Cl8. It is used as an insecticide and may reasonably be anticipated to be a carcinogen: Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)


Hospitals controlled by various types of government, i.e., city, county, district, state or federal.


Necrotizing Sialometaplasia
Sialometaplasia, Necrotizing

A benign, inflammatory, variably ulcerated, occasionally bilateral, self-healing lesion of the minor salivary glands that is often confused clinically and histologically with carcinoma.


Children, Hospitalized
Child, Hospitalized
Hospitalized Child


Spasmentral Dexetimide Tremblex Dexbenzetimid Dexbenzetimide dextro-Benzetimide R-16470 Benzetimide

A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.


Inequalities
Standard of Living
Socioeconomic Factors
High-Income Population
Factors, Socioeconomic
Land Tenure

Social and economic factors that characterize the individual or group within the social structure.