Autosomal Dominant Striatonigral Degeneration

Striatonigral Degeneration, Autosomal Dominant

A dominantly-inherited ATAXIA first described in people of Azorean and Portuguese descent, and subsequently identified in Brazil, Japan, China, and Australia. This disorder is classified as one of the SPINOCEREBELLAR ATAXIAS (Type 3) and has been associated with a mutation of the MJD1 gene on chromosome 14. Clinical features include progressive ataxia, DYSARTHRIA, postural instability, nystagmus, eyelid retraction, and facial FASCICULATIONS. DYSTONIA is prominent in younger patients (referred to as Type I Machado-Joseph Disease). Type II features ataxia and ocular signs; Type III features MUSCULAR ATROPHY and a sensorimotor neuropathy; and Type IV features extrapyramidal signs combined with a sensorimotor neuropathy. (From Clin Neurosci 1995;3(1):17-22; Ann Neurol 1998 Mar;43(3):288-96)


Nursing Care Plans
Goals of Care
Plans, Nursing Care
Patient Care Planning

Planned care program designed for a particular patient usually reflecting patient and family goals as well those institution and healthcare providers.


Nonsense Mutation
Nonsense Codon, Amber
Ochre Nonsense Codon
Codon, Termination, Premature
Opal Nonsense Mutation
Codon, Nonsense
Unassigned Codon
Amber Nonsense Codon
Nonsense Codon
Premature Termination Codon
Codon, Unassigned
Premature Stop Codon
Ochre Nonsense Mutation
Opal Nonsense Codon
Mutation, Nonsense
Amber Nonsense Mutation

A mutation that converts a sense codon (CODON) into a stop codon (CODON, TERMINATOR) or an unassigned codon and leads to the formation of truncated proteins.


Uncaria procumbens
Harpagophytum procumbens
Devils Claw
Harpagophytum

Species of Harpagophytum. Common name Devil's Claw is also a common name of some PROBOSCIDEA PLANT species.


A reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.


Common Melilot
Melilotus officinalis
Sweet Clover
Clover, Sweet
Yellow Sweetclover
Field Melilot
Melilotus
Yellow Sweet Clover

A plant genus of the family FABACEAE. Molded yellow sweet clover hay, in which the coumarin of sweet clover is converted to DICOUMAROL, is the causative agent of a hemorrhagic disorder in cattle - "hemorrhagic sweet clover disease" and featured in the history of anticoagulant drug development.


Postoperative Pulmonary Atelectasis
Compression Pulmonary Atelectasis
Lung Collapse
Atelectasis, Congestive
Congestive Atelectasis
Resorption Pulmonary Atelectasis
Contraction Pulmonary Atelectasis
Congestive Pulmonary Atelectasis
Pulmonary Atelectasis
Resorption Atelectasis
Compression Atelectasis
Atelectasis

Absence of air in the entire or part of a lung, such as an incompletely inflated neonate lung or a collapsed adult lung. Pulmonary atelectasis can be caused by airway obstruction, lung compression, fibrotic contraction, or other factors.


Never Event
Wrong-Site Surgery
Errors, Surgical
Mistake, Medical
Critical Incidents, Medical
Medical Mistakes
Medical Error of Omission
Surgical Errors
Medical Error of Commission
Medical Errors of Omission
Medical Errors of Commission
Wrong-Patient Surgery
Medical Mistake
Medical Errors
Critical Medical Incidents
Wrong-Procedure Errors
Surgical Error
Mistakes, Medical
Errors, Medical

Errors or mistakes committed by health professionals which result in harm to the patient. They include errors in diagnosis (DIAGNOSTIC ERRORS), errors in the administration of drugs and other medications (MEDICATION ERRORS), errors in the performance of surgical procedures, in the use of other types of therapy, in the use of equipment, and in the interpretation of laboratory findings. Medical errors are differentiated from MALPRACTICE in that the former are regarded as honest mistakes or accidents while the latter is the result of negligence, reprehensible ignorance, or criminal intent.


Recombinant Pituitary Growth Hormones
Growth Hormone, Pituitary
Somatotropin, Recombinant
Somatotropin
Growth Hormones Pituitary, Recombinant
Growth Hormone
Growth Hormone, Recombinant
Somatotropins, Recombinant
Recombinant Growth Hormones
Pituitary Growth Hormones, Recombinant
Recombinant Growth Hormone
Recombinant Somatotropins
Pituitary Growth Hormone

Growth hormone (somatotropin) can be synthesized with methods of recombinant DNA technology. Since action of GH is highly species-specific, recombinant growth hormones of several species (including humans, cows, and pigs) have been developed. They have been used to stimulate growth.


Psammomys
Gerbils
Rats, Sand
Meriones
Jird
Gerbillinae

A subfamily of the Muridae consisting of several genera including Gerbillus, Rhombomys, Tatera, Meriones, and Psammomys.


Liver Injury, Drug-Induced, Acute
Hepatitis, Toxic
Drug-Induced Liver Disease
Drug-Induced Liver Injury
Acute Liver Injury, Drug-Induced
Chemical and Drug Induced Liver Injury
Liver Injury, Drug-Induced
Hepatitis, Drug-Induced
Drug-Induced Acute Liver Injury
Toxic Hepatitis
Chemically-Induced Liver Toxicity

INFLAMMATION of the LIVER due to hepatocellular toxicity, caused by drug metabolites and chemicals from the environment.


Correction of Hearing Loss
Aural Habilitation
Habilitation of Hearing Impairment
Hearing Impaired Rehabilitation
Habilitation of Hearing Impaired
Correction of Auditory Perception
Rehabilitation of Hearing Impairment
Rehabilitation of Hearing Impaired
Correction of Hearing Impairment
Audiologic Rehabilitation
Audiologic Habilitation
Aural Rehabilitation

Procedures for restoring hearing impairment.


Ventilation, Middle Ear
Middle Ear Ventilation
Myringostomy
Tympanostomy Tube Insertion
Grommet Insertion
Tympanostomy

Ventilation of the middle ear in the treatment of secretory (serous) OTITIS MEDIA, usually by placement of tubes or grommets which pierce the TYMPANIC MEMBRANE.


Cancer of the Urinary Tract
Urologic Cancer
Neoplasms, Urologic
Cancer of Urinary Tract
Urological Neoplasms
Urinary Tract Neoplasms
Urologic Neoplasms
Urinary Tract Cancer
Urological Cancer

Tumors or cancer of the URINARY TRACT in either the male or the female.


RecQ3 Helicase
DNA Helicase RecQL4
DNA Helicase RecQL
ATP-Dependent DNA Helicase Q1
RecQ4 Helicase
RecQ2 Helicase
RECQL1 Helicase
RecQ Helicases
RecQ Family of DNA Helicases
DNA Helicase Q1
DNA Helicase, RecQ-like type 2
RecQ5 Helicase
RecQL2 Helicase
RecQ Protein
DNA-Dependent ATPase Q1
ATP-Dependent DNA Helicase Q5
RecQL3 Helicase
RecQ5L Helicase
ATP-Dependent DNA Helicase Q4
RecQL Helicase
RTS Helicase
RecQL4 Helicase

A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.


Mammut americanum
Mammut
American Mastodon
Mastodons

An extinct genus of large mammals in the family Mammutidae, that fed by browsing on tall plants. Eurasian species died out three million years ago, but some specimens of the American Mastodon survived the last Ice Age.


Iodothalamate
Iotalamic Acid
Iothalamic Acid, Monosodium Salt
Iothalamic Acid, Monosilver (1+) Salt
Iothalamic Acid
Methalamic Acid
Conray 420
Angio-Conray
Iothalamic Acid, Monosodium Salt, Dimer
Iothalamic Acid, Calcium (2:1) Salt
Iothalamate
Lopamidol
Sodium Iothalamate

A contrast medium in diagnostic radiology with properties similar to those of diatrizoic acid. It is used primarily as its sodium and meglumine (IOTHALAMATE MEGLUMINE) salts.


Particle-Mediated Epidermal Delivery of DNA

Particle Mediated Epidermal Delivery of DNA

Techniques where DNA is delivered directly into organelles at high speed using projectiles coated with nucleic acid, shot from a helium-powered gun (gene gun). One of these techniques involves immunization by DNA VACCINES, which delivers DNA-coated gold beads to the epidermis.


Hospital Pharmaceutic Service
Hospital Pharmacy Service
Pharmacy Service, Clinical
Pharmaceutical Service, Hospital
Service, Clinical Pharmacy
Service, Hospital Pharmaceutic
Service, Hospital Pharmacy
Hospital Pharmacy Services
Clinical Pharmacy Service
Service, Hospital Pharmaceutical
Pharmaceutic Service, Hospital
Hospital Pharmaceutical Service
Pharmacy Service, Hospital

Hospital department responsible for the receiving, storing, and distribution of pharmaceutical supplies.


Alisma
Common Water Plantain
Alisma plantago-aquatica

A plant genus of the family ALISMATACEAE. The flowers have 3 green sepals, 3 yellow and white petals, 6 stamens, and several pistils. Members contain TRITERPENES and SESQUITERPENES. Alisma is a component of tokishakuyakusan. Some species in this genus are called water plantain which is also a common name for other ALISMATACEAE plants.


Crab, Common Shore
Uca
European Shore Crab
Blue Crab
Crabs, True
Crab, Blue
Crabs, Short-Tailed
Brachyura
Crab, Green
Callinectes sapidus
Common Shore Crab
Carcinus maenas
Green Crab

Species in the genus Carcinus, family Portunidae, order BRACHYURA. Native of Europe, this voracious predator has invaded other continents affecting established habitats.


A naphthalene derivative that has specificity for RETINOIC ACID RECEPTORS. It is used as a DERMATOLOGIC AGENT for the treatment of ACNE.


Cyclic Acetylenes
Cycloalkenes
Cyclic Olefins
Cyclic Alkenes
Cycloalkynes
Cycloalkanes
Cycloparaffins

Alicyclic hydrocarbons in which three or more of the carbon atoms in each molecule are united in a ring structure and each of the ring carbon atoms is joined to two hydrogen atoms or alkyl groups. The simplest members are cyclopropane (C3H6), cyclobutane (C4H8), cyclohexane (C6H12), and derivatives of these such as methylcyclohexane (C6H11CH3). (From Sax, et al., Hawley's Condensed Chemical Dictionary, 11th ed)


Fibroblast-Derived Induced Pluripotent Stem Cells

Cells from adult organisms that have been reprogrammed into a pluripotential state similar to that of EMBRYONIC STEM CELLS.


Dimetane-Ten
para-Bromdylamine
Oraminic-2
Dimetane
Brompheniramine Maleate
p-Bromdylamine
Dimetapp Allergy
Brompheniramine
Chlorphed
Brompheniramine Maleate (1:1)

Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.


Myofascial Trigger Point Pain
Trigger Point Pain, Myofascial
Myofascial Pain Syndromes

Muscular pain in numerous body regions that can be reproduced by pressure on TRIGGER POINTS, localized hardenings in skeletal muscle tissue. Pain is referred to a location distant from the trigger points. A prime example is the TEMPOROMANDIBULAR JOINT DYSFUNCTION SYNDROME.


Rods and Cones
Retinal Photoreceptors
Photoreceptors, Vertebrate
Retinal Photoreceptor Cells
Photoreceptor Cells, Vertebrate
Vertebrate Photoreceptors
Photoreceptors, Retinal
Vertebrate Photoreceptor Cells

Specialized PHOTOTRANSDUCTION neurons in the vertebrates, such as the RETINAL ROD CELLS and the RETINAL CONE CELLS. Non-visual photoreceptor neurons have been reported in the deep brain, the PINEAL GLAND and organs of the circadian system.


Erythrina crista-galli
Erythrina
Indian Coral Tree
Erythrina verna
Erythrina mulungu
Erythrina cristagalli
Erythrina variegata

A genus of leguminous shrubs or trees, mainly tropical, yielding useful compounds such as ALKALOIDS and  PLANT LECTINS.


Cancer of the Muscle
Cancer of Muscle
Muscle Cancer
Neoplasms, Muscle
Muscle Neoplasms

Tumors or cancer located in muscle tissue or specific muscles. They are differentiated from NEOPLASMS, MUSCLE TISSUE which are neoplasms composed of skeletal, cardiac, or smooth muscle tissue, such as MYOSARCOMA or LEIOMYOMA.


Cell-Free Nucleic Acid
Circulating DNA
Cell-Free Nucleic Acids
Cell-Free Ribonucleic Acid
Cell-Free RNA
cirDNA
cirRNA
cfRNA
Cell-Free DNA
Cell-Free Deoxyribonucleic Acid
Circulating RNA
Circulating Nucleic Acids
cfDNA
Circulating Cell-Free Nucleic Acids

Nucleic acids (DNA or RNA) found circulating in SERUM; PLASMA; or other BODY FLUIDS.


Decanoic acid ester of nandrolone that is used as an anabolic agent to prevent or treat WASTING SYNDROME associated with severe chronic illness or HIV infection (HIV WASTING SYNDROME). It may also be used in the treatment of POSTMENOPAUSAL OSTEOPOROSIS.


Transcription Factor SRF
c-fos Serum Response Factor
p67-SRF
Serum Response Factor, p67
Serum Response Factor
p67 Serum Response Factor

A MADS domain-containing transcription factor that binds to the SERUM RESPONSE ELEMENT in the promoter-enhancer region of many genes. It is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.


Extinction, Biological
Species Extinction
Extinction, Mass
Extinction, Species
Mass Extinction

The ceasing of existence of a species or taxonomic groups of organisms.


Lysholm Knee Score
Tegner Activity Level
Lysholm Knee Scale
Lysholm Knee Scoring Scale
Tegner Activity Score
Tegner Activity Scale

Method of evaluating knee function following knee injury, treatment, and rehabilitation. It is based on the patient's activity level in work and sports activities.


Xenotropic Murine Leukemia Virus-related Virus Infection

Virus diseases caused by the RETROVIRIDAE.


Post-Traumatic Cancer
Post-Traumatic Neoplasms
Malignancies, Post-Traumatic
Neoplasms, Post-Traumatic

Tumors, cancer or other neoplasms caused by or resulting from trauma or other non-radiation injuries.


Swamps
Wetlands
Marsh
Marshes
Mangrove Forests
Bogs
Mangrove Swamps

Coastal wetlands found in tropical and subtropical regions.


Education, Health
Community Health Education
Health Education, Community
Health Education
Education, Community Health

Education that increases the awareness and favorably influences the attitudes and knowledge relating to the improvement of health on a personal or community basis.


Ovule
Megagametophyte
Female Gametes, Plant
Female Gametophytes
Megaspores, Plant

The element in plants that contains the female GAMETOPHYTES.


One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.


Currarino-Silverman Syndrome
Pectus Carinatum, Arcuate
Pectus Carinatum, Chondromanubrial
Pectus Carinatum, Chondrogladiolar
Pouter Pigeon Breast
Pectus Carinatum

A developmental anomaly characterized by abnormal anterior protrusion of the STERNUM and adjacent COSTAL CARTILAGE.


Cerebellar Gray Matter
Grey Matter
Gray Matter
Cerebellar Grey Matter

Region of CENTRAL NERVOUS SYSTEM that appears darker in color than the other type, WHITE MATTER. It is composed of neuronal CELL BODIES; NEUROPIL; GLIAL CELLS and CAPILLARIES but few MYELINATED NERVE FIBERS.


A carcinogen that is often used in experimental cancer studies.


Receptors, TNF-Related Apoptosis-Inducing Ligand

TNF-Related Apoptosis-Inducing Ligand Receptors

TNF-Related Apoptosis-Inducing Ligand Receptor 2

Tumor Necrosis Factor Receptor Superfamily, Member 10b

Tumor Necrosis Factor Receptor Superfamily, Member 10a

Receptors, Tumor Necrosis Factor, Member 10a

Receptors, Tumor Necrosis Factor, Member 10d

Receptors, Tumor Necrosis Factor, Member 10b


Retrograde Degeneration, Transneuronal
Axon Reaction
Trans-Synaptic Degeneration
Nissl Degeneration
Axonal Reaction
Retrograde Degeneration

Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.


Sepsis-Associated Encephalopathy
Sepsis-Associated Delirium
Sepsis Associated Encephalopathy
Sepsis Associated Delirium

Acute neurological dysfunction during severe SEPSIS in the absence of direct brain infection characterized by systemic inflammation and BLOOD BRAIN BARRIER perturbation.


Hydatid Cyst of Morgagni
Hydatid of Morgagni
Parovarian Cyst
Paratubal Cyst

A cyst (CYSTS) near the OVARY, derived from anomalies of the FALLOPIAN TUBES or the BROAD LIGAMENT. The paramesonephric type consists of ciliated cells similar to the oviduct epithelium. The mesonephric type consisted of an epithelium with minimally surface structures. They can be found on the thin oviduct (paratubal cysts) or near its fimbriated end (hydatid of Morgagni).


Retinitis Pigmentosa And Congenital Deafness

Dystrophia Retinae Pigmentosa-Dysostosis Syndrome

Autosomal recessive hereditary disorders characterized by congenital SENSORINEURAL HEARING LOSS and RETINITIS PIGMENTOSA. Genetically and symptomatically heterogeneous, clinical classes include type I, type II, and type III. Their severity, age of onset of retinitis pigmentosa and the degree of vestibular dysfunction are variable.


Secologanin Tryptamine Alkaloids
Rauwolfia Alkaloids
Strictosidine Derivatives
Alseroxylon
Rauvolfia Alkaloids
Terpenoid Indole Alkaloids
Monoterpenoid Indole Alkaloids
Secologanin Indole Alkaloids
Yohimbans


Mannheimia granulomatis
Pasteurella granulomatis
Mannheimia ruminalis
Mannheimia
Mannheimia varigena
Mannheimia glucosida

Species which encompass the trehalose-negative organisms previously known as Pasteurella haemolytica serovar 11.


Poppy, California
Eschscholzia californica
Eschscholzia

A plant genus of the family PAPAVERACEAE that contains benzo[c]phenanthridine alkaloids.


Emetic Effect
Emetic Effects
Emetic Agents
Emetics
Emetic Drugs

Agents that cause vomiting. They may act directly on the gastrointestinal tract, bringing about emesis through local irritant effects, or indirectly, through their effects on the chemoreceptor trigger zone in the postremal area near the medulla.


Anti-Anxiety Effect
Antianxiety Effects
Anti-Anxiety Agents
Anxiolytic Effect
Anti-Anxiety Effects
Tranquillizing Agents, Minor
Anxiolytics
Tranquilizing Agents, Minor
Anxiolytic Effects
Anti-Anxiety Drugs
Anxiolytic Agents
Antianxiety Effect

Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.


A synthetic pregnadiene derivative with anti-aldosterone activity.


In-Migration
Labor Migration
Temporary Migration
International Migration
Turnaround Migration
Chain Migration
Emigration and Immigration
Return Migration
Settlement and Resettlement
Out-Migration
Emigration
Immigration
Border Crossing

The process of leaving one's country to establish residence in a foreign country.


Marchiafava-Micheli Syndrome
Paroxysmal Hemoglobinuria, Nocturnal
Hemoglobinuria, Paroxysmal
Paroxysmal Cold Hemoglobinuria
Paroxysmal Nocturnal Hemoglobinuria
Paroxysmal Hemoglobinuria
Paroxysmal Hemoglobinuria, Cold

A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.


Saguinus oedipus
Marmoset, Cotton-Top
Saguinus
Tamarins, Long-tusked
Marmoset, Long-Tusked

A genus in the subfamily CALLITRICHINAE consisting of 12 species and found in Panama as well as South America. Species seen most frequently in the literature are S. oedipus (cotton-top marmoset), S. nigricollis, and S. fusicollis.


Efient
Effient
LY-640315
Prasugrel HCl
CS-747
LY640315
CS 747
LY 640315
Prasugrel
Prasugrel Hydrochloride

A piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those undergoing PERCUTANEOUS CORONARY INTERVENTIONS.


Basilar Artery Insufficiency
Vertebrobasilar Dolichoectasia
Vertebrobasilar Insufficiency
Vertebral Artery Stenosis
Vertebro-Basilar Insufficiency
Vertebral Artery Insufficiency
Vertebrobasilar Ischemia
Vertebral Artery Ischemia
Vertebro-Basilar Ischemia
Basilar Artery Stenosis
Basilar Insufficiency
Basilar Artery Ischemia

Localized or diffuse reduction in blood flow through the vertebrobasilar arterial system, which supplies the BRAIN STEM; CEREBELLUM; OCCIPITAL LOBE; medial TEMPORAL LOBE; and THALAMUS. Characteristic clinical features include SYNCOPE; lightheadedness; visual disturbances; and VERTIGO. BRAIN STEM INFARCTIONS or other BRAIN INFARCTION may be associated.


Bilateral Ovariectomy
Ovariectomy
Oophorectomy
Castration, Female


Apricots
Prunus armeniaca
Apricot
Apricot Tree

A plant species in the family ROSACEAE. It is the source of apricot fruit.


An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.


Endocrine Cancer
Endocrine Gland Neoplasms
Cancer of Endocrine Gland
Neoplasms, Endocrine Gland
Endocrine Gland Cancer
Cancer of the Endocrine Gland
Endocrine Gland Carcinoma
Carcinoma of Endocrine Gland

Tumors or cancer of the ENDOCRINE GLANDS.


United States Dept. of Health and Human Services

United States Department of Health and Human Services

United States Department of Human Services

United States Department of Health, Human Services

United States. Dept. of Health and Human Services

United States Department of Health, Education, and Welfare

United States Department of Health, Education and Welfare

Department of Health and Human Services (U.S.)

A cabinet department in the Executive Branch of the United States Government concerned with administering those agencies and offices having programs pertaining to health and human services.


Conserved Helix-Loop-Helix Ubiquitous Kinase

I Kappa B alpha-Associated Protein Kinase

A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit.


Lupus Erythematosus, Cutaneous, Subacute

A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the spread into other body systems. It has been classified into three forms - acute (= LUPUS ERYTHEMATOSUS, SYSTEMIC with skin lesions), subacute, and chronic (= LUPUS ERYTHEMATOSUS, DISCOID).


Ctenopharyngodon idellus
Carassius carassius
Carps
Silver Carp
Grass Carp
Hypophthalmichthys molitrix
Carp
Cyprinus carpio
Crucian Carp
Koi Carp
Cyprinus

Common name for Cyprinus carpio, the only member of the genus Cyprinus, though subspecies are described.


Co-Dependency, Psychological
Codependency, Psychology
Co-Dependency, Psychology
Psychological Co-Dependency
Psychological Co-Dependence
Psychological Codependence
Psychological Codependency
Codependency
Co Dependency, Psychology
Co Dependence, Psychology
Codependency, Psychological
Codependence

A relational pattern in which a person attempts to derive a sense of purpose through relationships with others.


Aronia melanocarpa
Photinia
Black Chokecherry Tree
Aronia
Black Chokeberry Tree
Photinia melanocarpa

A plant genus of the family ROSACEAE. The common names of chokeberry or chokecherry are also used for some species of PRUNUS.


An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.


Hepatic Ductular Hypoplasia, Syndromatic

Cholestasis with Peripheral Pulmonary Stenosis

A multisystem disorder that is characterized by aplasia of intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC), and malformations in the cardiovascular system, the eyes, the vertebral column, and the facies. Major clinical features include JAUNDICE, and congenital heart disease with peripheral PULMONARY STENOSIS. Alagille syndrome may result from heterogeneous gene mutations, including mutations in JAG1 on CHROMOSOME 20 (Type 1) and NOTCH2 on CHROMOSOME 1 (Type 2).


Sensorineural Hearing Loss
Cochlear Hearing Loss
Hearing Loss, Sensorineural
Hearing Loss, Cochlear

Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.


Spikenard
Bristly Sarsaparilla
Aralia nudicaulis
Aralia hispida
Aralia

A species of Aralia sometimes known by the common name of wild sarsaparilla, which is also the common name of some species such as SMILAX GLAUCA and SCHISANDRA GLABRA.


Polyneuropathy, Critical Illness
Polyneuropathy, Inherited
Polyneuropathy, Motor
Polyneuropathy, Acquired
Polyneuropathy, Familial
Polyneuropathies

Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.


Epithelial Amiloride-Sensitive Sodium Channel

Epithelial Sodium Channel, gamma Subunit

Sodium Channel, Nonvoltage-gated 1 Protein, beta Subunit

Epithelial Sodium Channel, delta Subunit

Epithelial Sodium Channel, alpha Subunit

Sodium Channel, Nonvoltage-gated 1 Protein, gamma Subunit

Sodium Channel, Nonvoltage-gated 1 Protein, delta Subunit

Sodium Channel, Nonvoltage-gated 1 Protein, alpha Subunit

Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.


Lead-Induced Nervous System Disease, Childhood

Poisoning, Lead, Nervous System, Childhood

Nervous System Disease, Lead-Induced, Childhood

Lead Poisoning, Nervous System, Childhood

Nervous System Poisoning, Lead, Childhood

Neurologic disorders occurring in children following lead exposure. The most frequent manifestation of childhood lead toxicity is an encephalopathy associated with chronic ingestion of lead that usually presents between the ages of 1 and 3 years. Clinical manifestations include behavioral changes followed by lethargy; CONVULSIONS; HALLUCINATIONS; DELIRIUM; ATAXIA; and vomiting. Elevated intracranial pressure (HYPERTENSION, INTRACRANIAL) and CEREBRAL EDEMA may occur. (From Adams et al., Principles of Neurology, 6th ed, p1210-2)


Dermatomyces
Arthrodermataceae
Keratinomyces
Cutaneous Fungus
Cutaneous Fungi
Dermatophytes
Ctenomyces
Nannizzia
Arthroderma

A family of ascomycetous fungi, order Onygenales, characterized by smooth ascospores. Genera in the family include Arthroderma, Keratinomyces, and Ctenomyces. Several well-known anamorphic forms are parasitic upon the skin.


Stratum Radiatum, CA3
CA3 Pyramidal Cell Layer
Hippocampus CA3 Field
CA3 Stratum Pyramidale
Regio Inferior of Hippocampus
CA3 Stratum Lucidum
Cornu Ammonis 3 Area
Hippocampal Sector CA3
CA3 Pyramidal Cell Area
CA3 Region, Hippocampal
CA3 Stratum Radiatum
CA3 Field of Hippocampus

Mossy fiber axon layer of the hippocampus CA3 field.


Physiological Absorption
Absorption, Systemic
Absorption, Physiological
Systemic Absorption

Uptake of substances by the body, tissues, or cells. The uptake may occur by various forms of BIOLOGICAL TRANSPORT or by simple DIFFUSION.


Temporomandibular Joint Arthrocentesis
Arthrocentesis,Temporomandibular Joint
Arthrocentesis, TMJ
Arthrocentesis
Aspiration,Temporomandibular Joint
Temporomandibular Joint Aspiration

Aspiration of SYNOVIAL FLUID from the TEMPOROMANDIBULAR JOINT cavity.


An anilide used as a long-acting local anesthetic. It has a differential blocking effect on sensory and motor neurons.


B Effector 1 Cells
B1 Lymphocytes
Be1 Cells
B Effector 2 Cells
Be2 Cells
B2 Lymphocytes
B-Lymphocyte Subsets
Effector B Cells
B-2 Lymphocytes
B-1 Lymphocytes
B-Lymphocytes, Effector
B-Cell Subsets
B-1 Cells

A classification of B-lymphocytes based on structurally or functionally different populations of cells.


Exudative Bronchiolitis
Constrictive Bronchiolitis
Bronchiolitis, Exudative
Bronchiolitis Obliterans
Bronchiolitis, Proliferative
Proliferative Bronchiolitis

A form that is characterized by partial or complete obstruction of bronchiolar lumens resulting from chronic bronchiolar inflammation, scarring, and smooth muscle hypertrophy.


Low T3 and Low T4 Syndrome
Low T3-High T4 Syndrome
Euthyroid Sick Syndromes
Low T3-Low T4 Syndrome
Non-Thyroidal Illness Syndrome
Low T3 High T4 Syndrome
Sick Euthyroid Syndrome
High T4 Syndrome
Low T3 Syndrome

Conditions of abnormal THYROID HORMONES release in patients with apparently normal THYROID GLAND during severe systemic illness, physical TRAUMA, and psychiatric disturbances. It can be caused by the loss of endogenous hypothalamic input or by exogenous drug effects. The most common abnormality results in low T3 THYROID HORMONE with progressive decrease in THYROXINE; (T4) and TSH. Elevated T4 with normal T3 may be seen in diseases in which THYROXINE-BINDING GLOBULIN synthesis and release are increased.


Saffron
Saffron Crocus
Crocus sativus
Crocus

A plant genus, in the IRIDACEAE family, known as a source of Saffron.


Gamanil
Lofepramine
Deftan
Lopramine
Lomont
Lofepramine Hydrochloride
Feprapax
Gamonil
Leo 640

A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to DESIPRAMINE.


Golfer's Elbow
Medial Epicondylitis
Elbow Tendinopathy

Inflammation (tendinitis) or degeneration (tendinosis) of the tendons of the elbow.


Andira
Leguminosae
Amorpha
Pea Family
Clathrotropis
Pithecolobium
Euchresta
Copaifera
Baptisia
Fabaceae
Machaerium
Afzelia
Colophospermum
Pithecellobium
Guibourtia
Delonix
Ceratonia
Tachigalia
Legumes
Stryphnodendron
Callerya

The large family of plants characterized by pods. Some are edible and some cause LATHYRISM or FAVISM and other forms of poisoning. Other species yield useful materials like gums from ACACIA and various LECTINS like PHYTOHEMAGGLUTININS from PHASEOLUS. Many of them harbor NITROGEN FIXATION bacteria on their roots. Many but not all species of "beans" belong to this family.


Arteriovenous Aneurysm
Aneurysm, Arteriovenous
Arteriovenous Fistula
Arteriovenous Fistulas

An abnormal direct communication between an artery and a vein without passing through the CAPILLARIES. An A-V fistula usually leads to the formation of a dilated sac-like connection, arteriovenous aneurysm. The locations and size of the shunts determine the degree of effects on the cardiovascular functions such as BLOOD PRESSURE and HEART RATE.


Biological Oxygen Demand Analysis
Biological Oxygen Demand
Chemical Oxygen Demand
Chemical Oxygen Demand Analysis
Biological Oxygen Demand Analyses
Chemical Oxygen Demand Analyses

Testing for the amount of biodegradable and unbiodegradable organic material in a water sample by measuring the quantity of oxygen consumed via use of an oxidizing agent such as potassium dichromate. The COD test results correlate to the BOD results and can be acquired in a short enough time to be useful for wastewater management.


Transgendered Persons
Transgender Persons
Two-Spirit Persons
Transgenders
Transsexual Persons
Transexuals

Those individuals with gender dysphoria and with a persistent desire to undergo SEX REASSIGNMENT PROCEDURES.


Joint Ventures
Hospital-Physician Joint Ventures
Joint Venture, Hospital-Physician
Organizations, Hospital-Physician
Joint Ventures, Hospital-Physician
Organizations, Physician-Hospital
Hospital-Physician Joint Venture
Hospital-Physician Organizations
Physician-Hospital Organizations

A formal financial agreement made between one or more physicians and a hospital to provide ambulatory alternative services to those patients who do not require hospitalization.


Passion Flower
Passiflora
Passiflora edulis
Passionflower
Granadilla
Passiflora incarnata
Purple Passionflower
Passiflora alata
Passionfruit

A plant genus of the family Passifloraceae, order Violales, subclass Dilleniidae, class Magnoliopsida. They are vines with ornamental flowers and edible fruit.


Retinal Cancer
Retinal Tumors
Cancer of the Retina
Neoplasms, Retinal
Cancer, Retinal
Tumors, Retinal
Retinal Neoplasms


Paternal Educational Status
Educational Achievement
Status, Educational
Achievement, Educational
Educational Status, Maternal
Educational Status, Paternal
Maternal Educational Status
Educational Status

Educational attainment or level of education of an individual.


Neurotransmitter Transport Proteins, Serotonin-Specific

Solute Carrier Family 6, Member 4 Protein

5-Hydroxytryptamine Plasma Membrane Transport Protein

Serotonin Plasma Membrane Transport Proteins

Serotonin Plasma Membrane Transporter Proteins

A sodium chloride-dependent neurotransmitter symporter located on the PLASMA MEMBRANE of BLOOD PLATELETS. It transports SEROTONIN from the EXTRACELLULAR SPACE into the platelet CYTOPLASM.


Protector Protein (Mixed-Function Oxidase Systems)

Thioredoxin-Dependent Peroxide Reductase 1

Thioredoxin-Dependent Peroxide Reductase 2

A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.


Patient Dumping
Health Care Transition
Patient Transfer
Transition of Care
Patient Transition
Care Transition
Patient Turfing

Movement of patients between different locations or settings with varying levels of care such as hospitals, primary and specialty care offices, nursing facilities, the patient's home and long-term care facilities.


Glu-Plasminogen
Plasminogen
Glutamyl Plasminogen
Profibrinolysin
Glutamic Acid 1-Plasminogen

Precursor of plasmin (FIBRINOLYSIN). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.


Muscle Tone Poor
Hypotonia
Decreased Muscle Tone
Muscle Tone Atonic
Floppy Muscles
Muscular Flaccidity
Hypotony, Muscle
Hypomyotonia
Muscular Hypotonia
Muscle Hypotonia
Neonatal Hypotonia
Flaccid Muscle Tone
Muscle Flaccidity
Unilateral Hypotonia

A diminution of the skeletal muscle tone marked by a diminished resistance to passive stretching.


Receptors, Nuclear and Cytoplasmic
Nuclear and Cytoplasmic Receptors
Hormone Receptors, Cytoplasmic
Nuclear Receptors
Receptors, Cytosolic and Nuclear
Intracellular Membrane Receptors
Nuclear Hormone Receptors
Receptors, Intracellular Membrane
Cytoplasmic Hormone Receptors
Receptors, Nuclear
Cytosolic and Nuclear Receptors
Receptors, Cytosol and Nuclear
Cytoplasmic and Nuclear Receptors
Cytosol and Nuclear Receptors
Cytoplasmic Receptors
Receptors, Cytoplasmic and Nuclear
Hormone Receptors, Nuclear
Receptors, Cytoplasmic

Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.


Capripoxvirus
Goat Pox Virus
Sheep Pox Virus
Sheeppox virus
Goatpox virus

Type species of the genus CAPRIPOXVIRUS.


A class of polyprenols which contain approximately 20 isoprene residues. Although considered ISOPRENOIDS, they terminate with an alpha-saturated isoprenoid group at the hydroxy end of the molecule.


Sterol Regulatory Element-Binding Protein 1

Sterol Regulatory Element Binding Protein 1c

Sterol Regulatory Element Binding Protein 1a

Adipocyte Determination And Differentiation Factor 1

SREBP1-C is an isoform of sterol regulatory element binding protein 1 that is a weak activator of GENETIC TRANSCRIPTION. It is the predominant form in LIVER and ADIPOCYTES, and it mediates INSULIN induced FATTY ACIDS synthesis.


Neovascularization, Optic Disc
Retinal Neovascularization
Neovascularization, Retinal
Optic Disk Neovascularization
Sea Fan Neovascularization
Optic Disc Neovascularization

Formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina.


A naphthyridine and fluoroquinolone derivative antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used for the treatment of community-acquired pneumonia and acute bacterial infections associated with chronic bronchitis.


19th Century History
History of Medicine, 19th Cent.
19th Cent. Medicine
Historical Events, 19th Century
Medicine, 19th Cent.
History, Nineteenth Century
19th Cent. History of Medicine
History, 19th Century
19th Cent. History (Medicine)
Medical History, 19th Cent.

Events of lasting impact or importance occurring in the 19th century.


Cation Transport Proteins
Cation Pumps
Cation Pump

Membrane proteins whose primary function is to facilitate the transport of positively charged molecules (cations) across a biological membrane.


Fyn Tyrosine Kinase
p60(fyn) Protein
Proto-Oncogene Protein c-syn
p59 c-fyn Protein
fyn Proto-Oncogene Proteins
Proto-Oncogene Protein p72(fyn)
c-fyn Protein
p60 c-fyn Protein
c-fyn Proto-Oncogene Proteins
p59(fyn) Protein
Proto-Oncogene Protein p60(fyn)
p72 c-fyn Protein
Proto-Oncogene Protein p59(fyn)
Proto-Oncogene Protein c-fyn
Protein-Tyrosine Kinase p59(fyn)
p72(fyn) Protein
Proto-Oncogene Proteins c-fyn

Src-family kinases that associate with T-CELL ANTIGEN RECEPTOR and phosphorylate a wide variety of intracellular signaling molecules.


Internal Urinary Sphincter
External Urinary Sphincter
Urethral Sphincters
Internal Vesical Sphincter
External Urethral Sphincter
Urethra
Internal Urethral Sphincter

Muscles that control the release of urine to the urethra. They consist of the internal and external urinary sphincters.


Soy Proteins
Soy Bean Proteins
Dietary Soybean Proteins
Soybean Proteins
Soy Protein

Proteins which are present in the edible portion of SOYBEANS.


Tullidora
Coyotillo
Karwinskia
Karwinskia humboldtiana

A plant genus of the family RHAMNACEAE that contains tullidinol (toxin T-544) and peroxisomicine (toxin T-514). It is sometimes called buckthorn but should not be confused with other plants called that.


Pregnancy Rate, Live-Birth
Rate, Pregnancy
Pregnancy Rate
Live-Birth Pregnancy Rate
Pregnancy Rates
Rates, Pregnancy

The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.


A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.


Sepsis in Pregnancy
Maternal Sepsis
Pregnancy, Infectious Complications
Complications, Infectious Pregnancy
Pregnancy Complications, Infectious
Infectious Pregnancy Complications
Sepsis during Pregnancy

Systemic infection during pregnancy, child-birth, post-abortion, or post-partum period often associated with organ dysfunction.


alpha-Tryptase
beta-Tryptase
gamma-Tryptase
gamma-Tryptases
delta-Tryptase
Skin Tryptase
delta-Tryptases
Tryptase
beta-Tryptases
alpha-Tryptases
Tryptases
Mast Cell Tryptase

A family of neutral serine proteases with TRYPSIN-like activity. Tryptases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.


Type X Procollagen
Collagen Type X, alpha1 Subunit
Collagen alpha1(X)
Collagen Type X
Procollagen Type X
Type X Collagen
Collagen Type X, alpha1 Chain

A non-fibrillar collagen found primarily in terminally differentiated hypertrophic CHONDROCYTES. It is a homotrimer of three identical alpha1(X) subunits.


Residencies, Dental
Residency
Residency, Dental
Dental Internship
Internship, Medical
Residency and Internship
Residencies, Medical
House Staff
Residency, Medical
Dental Internships
Internship and Residency
Internships, Dental
Medical Residencies
Internship
Dental Residency
Internship, Dental
Dental Residencies
Medical Residency

Programs of EDUCATION, MEDICAL, GRADUATE training to meet the requirements established by accrediting authorities.


Sensory Neuropathy, Glossopharyngeal Nerve

Glossopharyngeal Nerve Sensory Neuropathy

Diseases of the ninth cranial (glossopharyngeal) nerve or its nuclei in the medulla. The nerve may be injured by diseases affecting the lower brain stem, floor of the posterior fossa, jugular foramen, or the nerve's extracranial course. Clinical manifestations include loss of sensation from the pharynx, decreased salivation, and syncope. Glossopharyngeal neuralgia refers to a condition that features recurrent unilateral sharp pain in the tongue, angle of the jaw, external auditory meatus and throat that may be associated with SYNCOPE. Episodes may be triggered by cough, sneeze, swallowing, or pressure on the tragus of the ear. (Adams et al., Principles of Neurology, 6th ed, p1390)


Fertility Preferences
World Fertility Survey
Below Replacement Fertility
Fecundability
Fertility
Natural Fertility
Subfecundity
Differential Fertility
Fertility Determinants
Fertility, Below Replacement
Fertility Incentives
Marital Fertility
Fecundity

The capacity to conceive or to induce conception. It may refer to either the male or female.


Platinum(2+) ethanedioate (1R,2R)-1,2-cyclohexanediamine (1:1:1)

An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane, and with an oxalate ligand which is displaced to yield active oxaliplatin derivatives. These derivatives form inter- and intra-strand DNA crosslinks that inhibit DNA replication and transcription. Oxaliplatin is an antineoplastic agent that is often administered with FLUOROURACIL and FOLINIC ACID in the treatment of metastatic COLORECTAL NEOPLASMS.


Peromyscus
Mouse, Deer
Mice, Deer
Mice, White-Footed
Mouse, White-Footed

A genus of the subfamily SIGMODONTINAE consisting of 49 species. Two of these are widely used in medical research. They are P. leucopus, or the white-footed mouse, and P. maniculatus, or the deer mouse.


Sodium Dextran Sulfate
Dextran Sulfate Sodium
Dextran Sulfate

Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.


Eleuthero
Siberian Ginseng
Eleutherococcus
Ciwujia
Ginseng, Siberian
Eleutherococcus senticosus
Acanthopanax

A plant genus in the family ARALIACEAE, order Apiales, subclass Rosidae. It is best known as an adaptogen and a substitute for PANAX GINSENG.


env Polyprotein
Gene Products, env
env Glycoproteins
env Polyproteins
env Antigens
env Gene Products
env Protein

Retroviral proteins, often glycosylated, coded by the envelope (env) gene. They are usually synthesized as protein precursors (POLYPROTEINS) and later cleaved into the final viral envelope glycoproteins by a viral protease.


Copy Number Polymorphisms
Copy Number Variation, DNA
DNA Copy Number Changes
DNA Copy Number Variants
Copy Number Variants, DNA
Copy Number Changes, DNA
DNA Copy Number Change
DNA Copy Number Polymorphism
DNA Copy Number Variations
DNA Copy Number Variation
DNA Copy Number Polymorphisms

Stretches of genomic DNA that exist in different multiples between individuals. Many copy number variations have been associated with susceptibility or resistance to disease.


Phosphatidylinositol Transfer Protein alpha

Phosphatidylinositol Transfer Protein beta

Nonspecific Phospholipid Transfer proteins

A ubiquitous family of proteins that transport PHOSPHOLIPIDS such as PHOSPHATIDYLINOSITOL and PHOSPHATIDYLCHOLINE between membranes. They play an important role in phospholipid metabolism during vesicular transport and SIGNAL TRANSDUCTION.


Multiplex Ligation-Dependent Probe Amplification

A method similar to multiplex polymerase chain reaction that uses primers composed of two adjacently binding probe halves that when ligated together allow the amplification reaction to proceed as in the LIGASE CHAIN REACTION.


Occlusion Bodies, Viral
Viral Occlusion Body
Polyhedral Occlusion Bodies
Polyhedral Inclusion Bodies
Viral Occlusion Bodies
Occlusion Body, Viral
Occlusion-Derived Virion
Occluded Virions
Polyhedral Occlusion Body
Occluded Virus
Polyhedral Inclusion Body

A polyhedral shaped occlusion body of a BACULOVIRUS or CYPOVIRUS.


Alpha Motorneurons
Neurons, Motor
Motor Neurons, Alpha
Neurons, Alpha Motor
Motoneurons
Motor Neurons


Neem Tree
Melia azadirachta
Azadirachta indica
Azadirachta

A plant genus of the family MELIACEAE. Members contain azadirachtin A (a limonoid commonly referred to as azadirachtin) and other TRITERPENES. They have been used in PESTICIDES. The old name of Melia azadirachta is very similar to a related plant, MELIA AZEDARACH.


Ethylene Dibromides
1,2-Dibromoethane
Ethylene Bromide
Dowfume W85
sym-Dibromoethane
Dowfume W 85
Ethylene Dibromide

An effective soil fumigant, insecticide, and nematocide. In humans, it causes severe burning of skin and irritation of the eyes and respiratory tract. Prolonged inhalation may cause liver necrosis. It is also used in gasoline. Members of this group have caused liver and lung cancers in rodents. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), 1,2-dibromoethane may reasonably be anticipated to be a carcinogen.


Viral Encephalitis, California
Encephalitis, California
La Crosse Encephalitis
La Crosse Encephalitis Virus Infection
California Encephalitis
California Viral Encephalitis
Encephalitis, California, Viral
California Encephalitis Virus Infection

A viral infection of the brain caused by serotypes of California encephalitis virus (ENCEPHALITIS VIRUS, CALIFORNIA) transmitted to humans by the mosquito AEDES triseriatus. The majority of cases are caused by the LA CROSSE VIRUS. This condition is endemic to the midwestern United States and primarily affects children between 5-10 years of age. Clinical manifestations include FEVER; VOMITING; HEADACHE; and abdominal pain followed by SEIZURES, altered mentation, and focal neurologic deficits. (From Joynt, Clinical Neurology, 1996, Ch26, p13)


Developmental Neural Tube Defects
Diastematomyelia
Neuroenteric Cyst
Iniencephaly
Occult Spinal Dysraphism Sequence
Developmental Defects, Neural Tube
Neural Tube Defects
Tethered Spinal Cord Syndrome
Neural Tube Developmental Defects
Spinal Cord Myelodysplasia
Craniorachischisis
Acrania
Neurenteric Cyst
Tethered Cord Syndrome
Exencephaly
Occult Spinal Dysraphism

Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)


Receptor-Like Protein Tyrosine Phosphatases, Class VIII

Receptor-Like Protein Tyrosine Phosphatases, Class 8

Protein Tyrosine Phosphatase, Receptor Type N

Protein Tyrosine Phosphatase, Receptor-Type, N

A subclass of receptor-like protein tryosine phosphatases that contain an extracellular RDGS-adhesion recognition motif and a single cytosolic protein tyrosine phosphate domain.


Leukemia Lymphoma Virus Antibodies, Human T Cell

T-Cell Leukemia-Lymphoma Virus Antibodies, Human

T Cell Leukemia Lymphoma Virus Antibodies, Human

Leukemia-Lymphoma Virus Antibodies, Human T-Cell

Antibodies reactive with various types of human T-cell leukemia/lymphoma antigens or bovine leukemia virus antigens.


Glutaminic Acids
Glutamic Acid Derivatives
Glutamates
Glutamic Acids

Derivatives of GLUTAMIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the 2-aminopentanedioic acid structure.


Méfoxin
Mefoxin
Cefoxitin
Mefoxitin
MK-306
Cefoxitin Sodium

A semisynthetic cephamycin antibiotic resistant to beta-lactamase.


Neural Tissue Regeneration
Nerve Tissue Regeneration
Nervous Tissue Regeneration
Nerve Regeneration

Renewal or physiological repair of damaged nerve tissue.


Scavenger Receptors, Class C, Type I
SR-CI Protein
SR-C Proteins
Scavenger Receptor Class C Type I
Scavenger Receptors, Class C

A family of scavenger receptors with broad polyanionic ligand binding properties that are expressed in embryonic insect MACROPHAGES.


Angle's Classification
Cross Bite
Malocclusion
Tooth Crowding
Crossbite

Such malposition and contact of the maxillary and mandibular teeth as to interfere with the highest efficiency during the excursive movements of the jaw that are essential for mastication. (Jablonski, Illustrated Dictionary of Dentistry, 1982)


Nurses, Head
Head Nurses
Supervisory Nursing
Nursing, Supervisory
Charge Nurses

Administration of nursing services for one or more clinical units.


Fourth Cranial Nerve Palsy
Cranial Nerve IV Diseases
Superior Oblique Palsy, Neurogenic
Trochlear Nerve Palsy
Fourth Cranial Nerve Diseases
Fourth Nerve Palsy
Neurogenic Superior Oblique Palsy
Trochlear Nerve Diseases
Trochlear Nerve Disorders
Trochlear Neuropathy
Superior Oblique Myokymia

Diseases of the fourth cranial (trochlear) nerve or its nucleus in the midbrain. The nerve crosses as it exits the midbrain dorsally and may be injured along its course through the intracranial space, cavernous sinus, superior orbital fissure, or orbit. Clinical manifestations include weakness of the superior oblique muscle which causes vertical DIPLOPIA that is maximal when the affected eye is adducted and directed inferiorly. Head tilt may be seen as a compensatory mechanism for diplopia and rotation of the visual axis. Common etiologies include CRANIOCEREBRAL TRAUMA and INFRATENTORIAL NEOPLASMS.


Cetylpyridinium
Merocets
Angifonil
Cetylpyridinium Chloride
Cetylpyridinium Chloride Anhydrous
Cetylyre
Biosept
Catamium
Dobendan
Pyrisept
Cetamium
Ceepryn Chloride
Pristacin
Sterogenol
Hexadecylpyridinium
Cetylpyridium

Cationic bactericidal surfactant used as a topical antiseptic for skin, wounds, mucous membranes, instruments, etc.; and also as a component in mouthwash and lozenges.


Messenger RNA Localization Processes, Cellular

The process of moving specific RNA molecules from one cellular compartment or region to another by various sorting and transport mechanisms.


Basal Metabolism
Metabolic Rate, Basal
Basal Metabolic Rate
Resting Metabolic Rate
Metabolism, Basal

Metabolism (e.g., heat production) of an organism in an inactive, awake, fasting state. It may be determined directly by means of a calorimeter or indirectly by calculating the end products of oxidation within the organism or from the amount of oxygen utilized.


Cystadenofibroma
Benign Cystadenofibroma
Benign Clear Cell Adenofibroma
Clear Cell Adenofibroma
Borderline Cystadenofibroma
Borderline Clear Cell Adenofibroma

Benign or borderline malignant neoplasm of the ovary and surrounding tissues. It is characterized by tumor(s) with cystic glands which are lined by cuboidal EPITHELIAL CELLS with clear cytoplasm, resembling ENDOMETRIUM cells. The glands are separated by fibroblastic STROMAL CELLS.


Osteoporosis, Senile
Osteoporosis, Involutional
Senile Osteoporosis
Osteoporosis, Post-Traumatic
Osteoporosis
Osteoporosis, Age-Related
Age-Related Osteoporosis
Bone Loss, Age-Related

Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.


Corticomedial Nuclear Complex
Corticomedial Nuclei Complex
Cortical Amygdaloid Nucleus
Posterior Cortical Nucleus
Superficial Nuclei
Corticomedial Nuclear Group
Medial Amygdaloid Nucleus
Medial Amygdalar Nucleus
Anterior Amygdaloid Area
Corticomedial Nuclei
Superficial Nuclei, Amygdala
Anterior Amygdalar Area
Posterior Cortical Amygdaloid Nucleus
Medial Nucleus of Amygdala
Superficial Nuclei, Amygdaloid
Nucleus of Lateral Olfactory Tract

The rostral part of the amygdala with cortical-like layered structure. It receives major inputs from the OLFACTORY BULB and PIRIFORM CORTEX.


Meta-cognitive Control
Metacognitive Monitoring
Metacognitive Knowledge
Metamemory
Metacognitive Control
Meta-cognitive Monitoring
Meta-memory
Meta-cognition
Metaemotion
Meta-emotion
Meta-cognitive Awareness
Metacognitive Awareness
Metacognition

Awareness and understanding of one's own thought processes.


Erythromelalgia, Familial
Primary Erythromelalgia
Erythromelalgia, Primary
Erythermalgia
Primary Erythermalgia
Erythermalgia, Primary
Erythromelalgia
Familial Erythromelalgia

A peripheral arterial disease that is characterized by the triad of ERYTHEMA, burning PAIN, and increased SKIN TEMPERATURE of the extremities (or red, painful extremities). Erythromelalgia may be classified as primary or idiopathic, familial or non-familial. Secondary erythromelalgia is associated with other diseases, the most common being MYELOPROLIFERATIVE DISORDERS.


Arteritis, Giant Cell, Horton's
Giant Cell Arteritis, Horton
Giant Cell Arteritis
Cranial Arteritis
Temporal Arteritis
Giant Cell Aortitis, Horton's
Aortitis, Giant Cell
Juvenile Temporal Arteritis
Arteritis, Giant Cell, Horton
Horton's Disease
Horton Giant Cell Arteritis
Aortic Arteritis, Giant Cell
Giant Cell Aortic Arteritis
Horton's Giant Cell Arteritis
Giant Cell Aortitis
Arteritis, Temporal
Horton Disease

A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)


Open Reading Frames
Protein Coding Region
Unassigned Reading Frame
Unassigned Reading Frames
ORFs
Unidentified Reading Frame

Open reading frames that code for unidentified PROTEINS.


Phosphoinositide-3-Kinase, Class II, alpha Polypeptide

Phosphoinositide-3-Kinase, Class II, gamma Polypeptide

Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing beta Polypeptide

Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide

Phosphoinositide-3-Kinase, Class 2, beta Polypeptide

Phosphoinositide-3-Kinase, Class 2, gamma Polypeptide

Phosphoinositide-3-Kinase, Class II, beta Polypeptide

Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing alpha Polypeptide

Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing gamma Polypeptide

A subclass of phosphatidylinositol 3-kinases that have specificity for 1-phosphatidylinositol and 1-phosphatidylinositol 4-phosphate. Members of this subclass consist of a single subunit structure and are regulated by RECEPTOR TYROSINE KINASES; CYTOKINE RECEPTORS; and INTEGRINS.


A plant genus of the family ASTERACEAE. Flower buds contain farfaratin (SESQUITERPENES) and bisabolene epoxide.


Protein-Tyrosine Kinase C-Terminal Src Kinase

Protein tyrosine kinases that phosphorylate tyrosine residues located in the C-terminal tails of SRC-FAMILY KINASES.


Hypromellose
Methyl Hydroxypropyl Cellulose
K-8515
HPMC-K-100 M
HPMC 2910
Hydroxypropylmethylcellulose
Methocel E
Hydroxypropyl Methylcellulose
K8515
Hypromellose Derivatives
MHPC Polymer
Methyl-hydroxypropyl-cellulose
Methoxyhydroxypropylcellulose

Polymeric compounds that contain repeating units of hydroxypropyl methylcellulose. The properties of hypromellose polymers can vary greatly and are defined by their molecular weight, the percentage of hydroxyl groups, the percentage of hydroxypropyl groups, and viscosity measurements. They are found a broad variety of commercial products such as FOOD ADDITIVES; EXCIPIENTS; and LUBRICANTS.


An ergoline derivative and dopamine D2-agonist that inhibits PROLACTIN secretion. It is used in the management of HYPERPROLACTINEMIA, and to suppress lactation following childbirth for medical reasons. Cabergoline is also used in the management of PARKINSON DISEASE.


Rectal Tumors
Rectal Cancer
Rectum Cancer
Rectal Neoplasms
Neoplasms, Rectal
Rectum Neoplasms
Cancer of Rectum
Cancer of the Rectum


RNA, Long Non-Translated
Long Intergenic Non-Protein Coding RNA
Long ncRNA
LincRNAs
Long Noncoding RNA
RNA, Long Untranslated
Long Non-Coding RNA
Long ncRNAs
Long Non-Protein-Coding RNA
LINC RNA
RNA, Long Noncoding
lncRNA

A class of untranslated RNA molecules that are typically greater than 200 nucleotides in length and do not code for proteins. Members of this class have been found to play roles in transcriptional regulation, post-transcriptional processing, CHROMATIN REMODELING, and in the epigenetic control of chromatin.


Left Sided Breast Neoplasms
Right Sided Breast Cancer
Left Sided Breast Neoplasm
Left-Sided Breast Cancer
Right Sided Breast Neoplasm
Left-Sided Breast Neoplasms
Unilateral Breast Cancer
Unilateral Breast Neoplasms
Right-Sided Breast Cancer
Left Sided Breast Cancer
Right-Sided Breast Neoplasms

Tumors or cancer found specifically in the human right BREAST.


Fat, Intra-Abdominal
Intra-Abdominal Adipose Tissue
Visceral Fat
Intra-Abdominal Fat
Retroperitoneal Fat
Retroperitoneal Adipose Tissue
Abdominal Visceral Fat
Visceral Adipose Tissue

Fatty tissue inside the ABDOMINAL CAVITY, including visceral fat and retroperitoneal fat. It is the most metabolically active fat in the body and easily accessible for LIPOLYSIS. Increased visceral fat is associated with metabolic complications of OBESITY.


Decapod Crustaceans
Sicyonia
Decapods
Sicyoniidae
Rock Shrimp
Shrimp, Rock
Decapoda

Genus of marine shrimp, in the family Sicyoniidae.


Paroxetine, trans-(+)-Isomer
Paroxetine Maleate
FG-7051
Paroxetine Hydrochloride, Hemihydrate
BRL-29060
Paroxetine
Seroxat
Paroxetine Hydrochloride Anhydrous
Paroxetine, cis-(+)-Isomer
Paroxetine Hydrochloride Hemihydrate
Paroxetine, cis-(-)-Isomer
Aropax
Paroxetine Hydrochloride
Paxil
Paroxetine Acetate

A serotonin uptake inhibitor that is effective in the treatment of depression.


Endoscopy, Pleural
Pleural Endoscopy
Surgery, Thoracoscopic
Surgical Procedures, Thoracoscopic
Thoracoscopic Surgery
Thoracoscopy
Pleuroscopy
Thoracoscopic Surgical Procedures

Endoscopic examination, therapy or surgery of the pleural cavity.


Retroviruses, Type D
Oncoviruses, Type D
Fibroblast Virus, Human, Permanent
Oncoviruses Type B
Type B Retroviruses, Mammalian
Type D Oncoviruses
Type B Oncoviruses
Retroviruses Type B, Mammalian
Type B Oncoviruses, Mammalian
Retroviruses Type D
Type D Oncornaviruses
Type D Retroviruses
Betaretrovirus
Mammalian Type B Retroviruses
Oncoviruses Type B, Mammalian

Previously a genus of the family RETROVIRIDAE consisting of oncogenic exogenous retroviruses that contain type D particles. It included the MASON-PFIZER MONKEY VIRUS. Now it represents one of the two kinds of viruses in the genus BETARETROVIRUS. The core of the type D viruses is the intracytoplasmic type A particle and its mechanism of budding from the cell membrane is similar to the type B oncoviruses.


Aspirin Tolerance Test
Bleeding Time, Template
Ivy Method
Duke Method
Template Bleeding Time
Bleeding Time

Duration of blood flow after skin puncture. This test is used as a measure of capillary and platelet function.


Knee Replacement Arthroplasties
Partial Knee Arthroplasty
Unicompartmental Knee Replacement
Total Knee Replacement
Replacement, Total Knee
Replacement Arthroplasties, Knee
Arthroplasty, Knee Replacement
Knee Replacement Arthroplasty
Knee Replacement, Total
Arthroplasties, Knee Replacement
Replacement Arthroplasty, Knee
Knee Arthroplasty, Total
Knee Arthroplasty
Arthroplasty, Replacement, Knee
Partial Knee Replacement
Arthroplasties, Replacement, Knee
Arthroplasty, Replacement, Partial Knee
Unicompartmental Knee Arthroplasty
Unicondylar Knee Arthroplasty
Unicondylar Knee Replacement


A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.


Hydroxyacetate Ethers
Glycolate Ethers
Glycolates
Hydroxyacetic Acids
Hydroxyacetates
2-Hydroxyacetates

Derivatives of ACETIC ACID which contain an hydroxy group attached to the methyl carbon.


Vaginal Foam
Vaginal Gel
Vaginal Foams
Vaginal Jellies
Vaginal Creams, Foams and Jellies
Vaginal Tablet
Vaginal Jelly
Vaginal Creams, Foams, and Jellies
Vaginal Cream
Vaginal Tablets
Vaginal Creams

Medicated dosage forms for topical application in the vagina. A cream is a semisolid emulsion containing suspended or dissolved medication; a foam is a dispersion of a gas in a medicated liquid resulting in a light, frothy mass; a jelly is a colloidal semisolid mass of a water soluble medicated material, usually translucent.


Enchondromatosis with Multiple Cavernous Hemangiomas

Dyschondroplasia and Cavernous Hemangioma

Benign growths of cartilage in the metaphyses of several bones.


Sperm-Egg Penetration
Sperm-Egg Interactions
Sperm Penetration
Sperm-Zona Pellucida Penetration
Sperm-Oocyte Penetration
Gamete Interactions
Egg-Sperm Interactions
Oocyte-Sperm Interactions
Sperm-Ovum Interactions
Ovum-Sperm Interactions
Sperm-Oocyte Interactions
Sperm-Ovum Penetration

Interactive processes between the oocyte (OVUM) and the sperm (SPERMATOZOA) including sperm adhesion, ACROSOME REACTION, sperm penetration of the ZONA PELLUCIDA, and events leading to FERTILIZATION.


Extended Focused Assessment with Sonography for Trauma

Focused Assessment with Sonography of Trauma

Rapid bedside ultrasound examination performed by medical personnel (surgeons, emergency physicians, paramedics and others), as a screening test for blood around the heart (PERICARDIAL EFFUSION) or abdominal organs (HEMOPERITONEUM) after trauma.


beta-Glucosidases
Cellulases
Cellulase Enzyme Systems
Laminarinase
Endoglucanase I
Endocellulases
Cellulase Enzyme System
Endocellulase
Exocellulases
Avicelase II
Avicelase
Exo-cellulase
Exocellulase

A family of glycosidases that hydrolyse crystalline CELLULOSE into soluble sugar molecules. Within this family there are a variety of enzyme subtypes with differing substrate specificities that must work together to bring about complete cellulose hydrolysis. They are found in structures called CELLULOSOMES.


Childhood Tic Disorders
Tic Disorder, Transient
Transient Tic Disorder
Motor Tic Disorders
Tic Disorder, Chronic Motor or Vocal
Tic Disorders, Vocal
Tic Disorders, Motor
Chronic Motor or Vocal Tic Disorder
Tic Disorders
Motor or Vocal Tic Disorder, Chronic
Post-Traumatic Tic Disorder
Tic Disorders, Childhood
Tic Disorder, Post-Traumatic
Vocal Tic Disorders

Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994)


Codon Usage Bias
Synonymous Codon Usage
Codon Usage
Codon Usage Pattern
Codon Bias
Codon Preference

The frequency of occurrence, in a specific organism's DNA sequence, of one of several potential synonymous codons that code for a particular amino acid. Frequently, there is a nonrandom pattern (bias) in the usage of a particular codon or codons over other synonymous codons.


Praecuneus
Parietal Region
Posterior Paracentral Lobule
Angular Gyrus
Marginal Sulcus
Gyrus Supramarginalis
Prelunate Gyrus
Posterior Parietal Cortex
Parietal Lobe
Supramarginal Gyrus
Precuneus Cortex
Precuneus
Intraparietal Sulcus
Parietal Cortex
Parietal Lobule
Gyrus Angularis

Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.


Millet, Koracan
Eleusine
Millet, Finger
Indian Finger Millet
Grass, Goose
Eleusine coracana
Goosegrass
Eleusine indica
Millet, Indian Finger

A plant genus of the family POACEAE. Finger millet or raggee (E. coracana) is an important food grain in southern Asia and parts of Africa.


Bassariscus astutus
Coatis
Coatimundis
Nasua
Procyonidae
Ringtails

A family of long-tailed terrestrial omnivores that includes RACCOONS, ringtails, and coatimundis.


Syntaxin 1 Protein
Syntaxin A Protein
Syntaxin-1A Protein
Syntaxin-2 Protein
Syntaxin-2
HPC-1 Protein
Syntaxin-1B
p35b Protein
P35B Antigen
Syntaxin-1C
Syntaxin-1A
Syntaxin 1
Syntaxin-1C Protein
Neuronal Cell Membrane Antigen, HPC-1
Syntaxin 1A
Syntaxin-1B Protein
Syntaxin A

A neuronal cell membrane protein that combines with SNAP-25 and SYNAPTOBREVIN 2 to form a SNARE complex that leads to EXOCYTOSIS.


An indole-heptanoic acid derivative that inhibits HMG COA REDUCTASE and is used to treat HYPERCHOLESTEROLEMIA. In contrast to other statins, it does not appear to interact with other drugs that inhibit CYP3A4.


Saline-Tolerant Plants
Saline-Resistant Plants
Plants, Salt-Tolerant
Halophytes
Halophilic Plants
Salt-Resistant Plants
Salt-Tolerant Plants
Salt-Adapted Plants
Halophytic Plants

Plants that have adapted to or require a high concentration of salt.


Cytolipins Lacto-N-neotetraosylceramide Globosides Lacto-N-tetraosylceramide Lactoneotetraosylceramide

Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.


An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.


Social Exploitation
Social Problems
Labor Exploitation

The process by which the results of the labor of one social group is transferred as the benefit of another group.


Renal Epithelial Sodium Channel Blockers

Renal Epithelial Sodium Channel Inhibitors

A subclass of sodium channel blockers that are specific for EPITHELIAL SODIUM CHANNELS.


Inherited Errors of Amino Acid Metabolism

Amino Acid Metabolism, Inherited Disorders

Disorders affecting amino acid metabolism. The majority of these disorders are inherited and present in the neonatal period with metabolic disturbances (e.g., ACIDOSIS) and neurologic manifestations. They are present at birth, although they may not become symptomatic until later in life.


Ictaluridae
Ictalurus punctatus
Pylodictus
Pylodictis
Catfishes, Channel
Bullhead Catfishes
Ameiurus
Ictalurus
Channel Catfishes
Noturus
Catfish, Channel
Channel Catfish

A family of North American freshwater CATFISHES. It consists of four genera (Ameiurus, Ictalurus, Noturus, Pylodictis,) comprising several species, two of which are eyeless.


Methodology, Evaluation
Evaluation Studies as Topic
Pre-Post Tests
Qualitative Evaluation
Evaluation Report
Use-Effectiveness
Theoretical Effectiveness
Evaluation Indexes
Quantitative Evaluation
Evaluation Research
Critique
Evaluation Methodology

Works about studies that determine the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies.


A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.


Sotalol
Sotalol Monohydrochloride
MJ-1999
Sotalol Hydrochloride
Darob

An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.


Economic and Social Commission for Asia and the Pacific

United Nations High Commissioner for Refugees (UNHCR)


Community Healthcare
Services, Community Health
Community Health Services
Health Services, Community
Community Health Care

Diagnostic, therapeutic and preventive health services provided for individuals in the community.


Mannose-Binding Protein-Associated Serine Proteases

MBP-Associated Serine Protease-Related Protein

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.


Soda Pop
Soft Drinks
Carbonated Beverages
Carbonated Drinks


Yolk Proteins
Egg Shell Proteins
Ovum Proteins
Egg Yolk Proteins
Egg White Proteins
Egg Proteins

Proteins which are found in eggs (OVA) from any species.


Diaphanous-Related Formin Homology Proteins

A family of multidomain microfilament proteins associated with ACTIN FILAMENTS. They generally have multiple Formin-Homology domains (e.g., FH2 domain) and additionally have a RhoGTPase-binding domain and a diaphanous inhibitory domain. Formins and homologs are involved in actin reorganization.


Endothelin-Converting Metalloprotease 2
Endothelin-Converting Enzyme II
Endothelin-Converting Enzyme 2
Endothelin-Converting Enzyme 1
Endothelin-Converting Enzymes
Endothelin Converting Enzyme-1a
Endothelin-Converting Enzyme-1b
Endothelin Converting Enzyme
ECE-1beta
Metalloprotease ECE-2
Endothelin-Converting Enzyme

Converts BIG ENDOTHELIN to ENDOTHELIN-1 through hydrolysis of the TRYPTOPHAN (21)-VALINE (22) bond. Mutations in the endothelin-converting enzyme 1 (ECE1) gene are associated with cases of HIRSCHSPRUNG DISEASE with cardiac defects and autonomic dysfunction.


Mouse, SCID-hu
SCID-hu Mice
Severe Combined Immunodeficient Mice
SCID Mice
Mice, SCID
Immunodeficient Mice, Severe Combined
Mouse, SCID

Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.


Cerastes Venoms
Cerastes Venom
Egyptian Sand Viper Venom
Viper Venoms
Viper Venom
Viperotoxin

Venoms from SNAKES of the viperid family. They tend to be less toxic than elapid or hydrophid venoms and act mainly on the vascular system, interfering with coagulation and capillary membrane integrity and are highly cytotoxic. They contain large amounts of several enzymes, other factors, and some toxins.


DNAase I
DNA Nicking Enzyme
DNA Endonuclease
Dornavac
DNase I
Endonuclease I
T7-Endonuclease I
Deoxyribonuclease I
Nickase
Thymonuclease
Pancreatic DNase
T4-Endonuclease II
Streptodornase

An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.


Midurethral Slings
Mid-Urethral Slings
Suburethral Slings
Trans-Obturator Tape
Male Slings
Tensionless Vaginal Tape
Transobturator Tape
Transobturator Suburethral Tape
Urethral Slings
Tension-Free Vaginal Tape
Male Urethral Slings

Support structures, made from natural or synthetic materials, that are implanted below the URETHRA to treat URINARY STRESS INCONTINENCE.


Homoharringtonine
Omacetaxine
Omacetaxine Mepesuccinate
Ceflatonin
Synribo
Cephalotaxine
Homoharringtonine (3(R))-isomer

Semisynthetic derivative of harringtonine that acts as a protein synthesis inhibitor and induces APOPTOSIS in tumor cells. It is used in the treatment of MYELOID LEUKEMIA, CHRONIC.


Taste Deterrents
Aversion Agents
Aversive Agents
Pungent Agents
Bittering Agents
Bitterants

Chemicals added to pharmacologic preparations, poisonous household goods, and other chemicals to discourage their abuse or consumption.


Direct-Acting Oral Anticoagulants
Direct Factor Xa Inhibitors
Factor Xa Inhibitors

Endogenous factors and drugs that inhibit or block the activity of FACTOR XA.


Asparaginase
Asparaginase medac
Kidrolase
Leunase
Elspar
Paronal
Crasnitin
Asparagine Deaminase
Asparaginase II
Colaspase
Erwinase

A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.


Plum, Waika
Rheedia
Hypericaceae
Clusiaceae
Allanblackia
Psorospermum
Cratoxylum

The mangosteen plant family (sometimes classified as Guttiferae; also known as Hypericaceae) of the order THEALES, subclass Dilleniidae, class Magnoliopsida. It includes trees and shrubs with resinous, sticky sap, usually with broad-ended, oblong, leathery leaves with a strong, central vein, flowers with many stamens.


Cosmetic Reconstructive Surgical Procedures

Reconstructive Surgical Procedures, Esthetic

Reconstructive Surgical Procedures, Cosmetic

Procedures used to reconstruct, restore, or improve defective, damaged, or missing structures.


Neurotoxins
Excitatory Neurotoxins
Alpha-Neurotoxins
Excitotoxins
Excitotoxin

Toxic substances from microorganisms, plants or animals that interfere with the functions of the nervous system. Most venoms contain neurotoxic substances. Myotoxins are included in this concept.


One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.


Genome Instability
Genomic Instability
Genomic Stability
Genome Stability

An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.


Scrapie PrP
PrP 33-35
Scrapie PrP 33-35
PrPSc Proteins
Scrapie Virus
PrP (CJD)
PrP-res
HaSp 33-37
Scrapie HaSp33-37 Protein
Scrapie Agent
PrP (GSS)
Sp 33-35

Abnormal isoform of PRION PROTEINS resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).


Otters
Lontra canadensis
Lutra
North American River Otter
Giant Otters
Pteronura
Lontra
Sea Otters
Enhydra lutris
Aonyx
Clawless Otters


A selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. It is used in patients with CONGESTIVE HEART FAILURE.


Cell Signaling
Signal Transduction Systems
Signal Pathways
Signal Transduction
Signal Transduction Pathways
Receptor Mediated Signal Transduction
Receptor-Mediated Signal Transduction

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.


Coban
Monensin-A-Sodium Complex
Monensin Monosodium Salt
Monensin
Monensin Sodium
Rumensin

An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.


Lasers, Gold Vapor
Lasers, Nitrogen
Xenon Ion Lasers
Lasers, Xenon Ion
HeNe Lasers
Lasers, CO2
Carbon Dioxide Lasers
Lasers, Metal Vapor
Argon Ion Lasers
Lasers, Helium Neon Gas
Helium Lasers
Lasers, Copper Vapor
Copper Vapor Lasers
CO2 Lasers
Gold Vapor Lasers
Lasers, Helium
Metal Vapor Lasers
Gas Lasers
Helium Neon Gas Lasers
Lasers, Argon Ion
Lasers, Gas
Nitrogen Lasers
Lasers, Carbon Dioxide

Lasers in which a gas lasing medium is stimulated to emit light by an electric current or high-frequency oscillator.


Vitamin C
Magnesium Ascorbate
Ascorbic Acid
Sodium Ascorbate
Magnorbin
Magnesium Ascorbicum
Ferrous Ascorbate
L-Ascorbic Acid
Ascorbic Acid, Monosodium Salt
Hybrin
Magnesium di-L-Ascorbate

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.


Transepithelial and Transendothelial Migration

Transendothelial and Transepithelial Migration

The passage of cells across the layer of EPITHELIAL CELLS, i.e. the EPITHELIUM.


Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.


Etodolac, (S)-Isomer
Lodine
AY-24236
Etodolac, Monosodium Salt
Etodolac, Monosodium Salt, (S)-Isomer
Etodolac, Monosodium Salt, (+-) Isomer
AY-24,236
Etodolac, (+-)-Isomer
Etodolac, (-)-Isomer
Ultradol
Etodolac
Ramodar
Etodolic Acid

A non-steroidal anti-inflammatory agent and cyclooxygenase-2 (COX-2) inhibitor with potent analgesic and anti-arthritic properties. It has been shown to be effective in the treatment of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; and in the alleviation of postoperative pain (PAIN, POSTOPERATIVE).


Broad-beta Lipoproteins
Floating beta-Lipoproteins
beta-Very-Low-Density Lipoproteins
alpha2-Very-Low-Density Lipoproteins
Lipoprotein, IDL
beta-VLDL
alpha2-VLDL
beta-VLDL Lipoproteins
Lipoproteins, Intermediate Density
alpha2-VLDL Lipoprotein
Lipoproteins, IDL
Intermediate-Density Lipoproteins
Intermediate Density Lipoproteins

A mixture of very-low-density lipoproteins (VLDL), particularly the triglyceride-poor VLDL, with slow diffuse electrophoretic mobilities in the beta and alpha2 regions which are similar to that of beta-lipoproteins (LDL) or alpha-lipoproteins (HDL). They can be intermediate (remnant) lipoproteins in the de-lipidation process, or remnants of mutant CHYLOMICRONS and VERY-LOW-DENSITY LIPOPROTEINS which cannot be metabolized completely as seen in FAMILIAL DYSBETALIPOPROTEINEMIA.


Lower Brachial Plexus Palsy
Brachial Plexus Neuropathies
Lower Brachial Plexus Neuropathy
Brachial Plexus Diseases
Erb's Palsy
Brachial Plexus Disorders
Klumpke Paralysis
Erb Paralysis
Upper Brachial Plexus Neuropathy
Middle Brachial Plexus Neuropathy
Brachial Plexopathy
Dejerine-Klumpke Palsy
Paralysis of the Lower Brachial Plexus
Erb-Duchenne Paralysis
Klumpke's Palsy

Diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the BRACHIAL PLEXUS. Clinical manifestations include regional pain, PARESTHESIA; MUSCLE WEAKNESS, and decreased sensation (HYPESTHESIA) in the upper extremity. These disorders may be associated with trauma (including BIRTH INJURIES); THORACIC OUTLET SYNDROME; NEOPLASMS; NEURITIS; RADIOTHERAPY; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp1351-2)


Event History Analysis
Life Experiences
Life Change Events
Analysis, Event History

Those occurrences, including social, psychological, and environmental, which require an adjustment or effect a change in an individual's pattern of living.


Data Masking
De-Identification
Deidentification
Data Anonymization

Removal of personally identifiable information via encryption or other methods.


Gestational Trophoblastic Disease
Trophoblastic Neoplasms, Gestational
Gestational Trophoblastic Neoplasia
Gestational Trophoblastic Neoplasms

Gestational Trophoblastic diseases that are malignant. It does not include HYDATIDIFORM MOLE. However, there is a minority of authors that consider the term gestational trophoblastic neoplasia synonymous with gestational trophoblastic disease.


Depressive Disorder
Depression, Neurotic
Depressive Syndrome
Melancholia
Depression, Endogenous
Neurosis, Depressive
Depression, Unipolar
Unipolar Depression

An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.


Oplopanax horridus
Echinopanax
Oplopanax
Ginseng, Alaskan
Echinopanax horridus
Devil's Club

A plant genus in the family ARALIACEAE, order Apiales, subclass Rosidae. It is the source of cirensenosides (triterpenoid saponins).


Lateral Sinus Thrombophlebitis
Septic Phlebitis, Lateral Sinus
Thrombosis, Lateral Sinus
Phlebitis, Lateral Sinus, Septic
Transverse Sinus Thrombosis
Lateral Sinus Thrombosis

Formation or presence of a blood clot (THROMBUS) in the LATERAL SINUSES. This condition is often associated with ear infections (OTITIS MEDIA or MASTOIDITIS) without antibiotic treatment. In developed nations, lateral sinus thrombosis can result from CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; NEUROSURGICAL PROCEDURES; THROMBOPHILIA; and other conditions. Clinical features include HEADACHE; VERTIGO; and increased intracranial pressure.


Esophageal Varix
Gastric Varices
Esophageal and Gastric Varices
Esophageal Varices
Gastric Varix

Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).


ORG-3770
Remeron
Org 50081
ORG 3770
(S)-Mirtazapine
(N-Methyl-11C)mirtazapine
Esmirtazapine
6-Azamianserin
Norset
Zispin
Mirtazapine
Rexer
Remergil

A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.


Cancer of the Bone
Cancer of Bone
Neoplasms, Bone
Bone Cancer
Bone Neoplasms

Tumors or cancer located in bone tissue or specific BONES.


Life History Characteristics
Life History Traits
Life History Strategies
Life History Strategy
Life History Theory
Life History Variation

Morphological or behavioral traits influenced by various living conditions that a population encounters especially as it pertains to REPRODUCTION and survival of the population (see POPULATION DYNAMICS) such as age at first reproductive event, number and size of offspring, and lifespan.


Spectacled Cobra
Philippine Cobra
Naja atra
Chinese Cobra
Naja naja
Naja oxiana
Asiatic Cobra
Naja naja philippinensis
Naja kaouthia
Monocled Cobra
Indian Spectacled Cobra
Asian Cobra
Central Asian Cobra
Naja naja oxiana
Naja naja atra
Naja naja kaouthia
Indian Cobra

Species of cobra (Naja) indigenous to the Indian Subcontinent, Southern Asia, and adjacent islands.


Esidrex Sectrazide Dihydrochlorothiazide HCTZ Oretic Hydrochlorothiazide HydroDIURIL Dichlothiazide Esidrix Hypothiazide

A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.


Electronic Transmission of Prescriptions

The use of COMPUTER COMMUNICATION NETWORKS to store and transmit medical PRESCRIPTIONS.


One Parent Family
Single-Parent Family
Family, Single-Parent
One-Parent Family
Single Parent Family

A household that includes children and is headed by one adult.


Flurodex
5-FU
Fluracedyl
Haemato-FU
5-Fluorouracil-Biosyn
5-HU Hexal
Fluoroplex
Carac
5-FU Lederle
Fluorouracil Monopotassium Salt
Fluorouracil
5-Fluorouracil
Fluoruracil
Fluorouracil-GRY
Onkofluor
Fluorouracil Monosodium Salt
Efudex
Efudix
5-FU Medac
Fluorouracile Dakota
5FU
Fluorouracilo Ferrer Far
Fluoro-Uracile ICN
Ribofluor
Fluorouracil Potassium Salt
Neofluor
Adrucil
Fluorouracil Mononitrate

A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.


Lymphocyte Phenotyping
Lymphocyte Immunophenotyping
Lymphocyte Subtyping
Immunologic Subtyping
Immunophenotyping
Immunologic Subtypings
Subtyping, Immunologic
Subtypings, Immunologic

Process of classifying cells of the immune system based on structural and functional differences. The process is commonly used to analyze and sort T-lymphocytes into subsets based on CD antigens by the technique of flow cytometry.


A stable synthetic analog of methionine enkephalin (ENKEPHALIN, METHIONINE). Actions are similar to those of methionine enkephalin. Its effects can be reversed by narcotic antagonists such as naloxone.


Arthroplasty
Bone Tunnel Enlargement
Bone Tunnel Widening

Surgical reconstruction of a joint to relieve pain or restore motion.


Cisordinol alpha-Clopenthixol Zuclopenthixol Clopenthixol

A thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.


A pyridine and diphosphonic acid derivative that acts as a CALCIUM CHANNEL BLOCKER and inhibits BONE RESORPTION.


Myosin S-2
Myosin Subfragment-1
H-Meromyosin
Actin S1 ATPase
Myosin Subfragments
Actoheavy Meromyosin
Heavy Meromyosin Subfragment-2
Actomyosin Subfragment 1 ATPase
Light Meromyosin
Meromyosin Subfragments
ATPase, Actin-S1
Heavy Meromyosin
Myosin Rod
Myosin S-1
Actomyosin Subfragments
Heavy Meromyosin Subfragment-1
Myosin Subfragment-2

Parts of the myosin molecule resulting from cleavage by proteolytic enzymes (PAPAIN; TRYPSIN; or CHYMOTRYPSIN) at well-localized regions. Study of these isolated fragments helps to delineate the functional roles of different parts of myosin. Two of the most common subfragments are myosin S-1 and myosin S-2. S-1 contains the heads of the heavy chains plus the light chains and S-2 contains part of the double-stranded, alpha-helical, heavy chain tail (myosin rod).


Indirect Enzyme Assays
Enzymatic Assays
Enzyme Assays
Indirect Enzymatic Assays

Sensitive detection methods using enzymes to indirectly measure substances that would normally be difficult to quantitate.


Deforestation
Carrying Capacity
Natural Resources Conservation
Environmental Protection
Desertification
Protection, Environmental
Conservation of Natural Resources

The protection, preservation, restoration, and rational use of all resources in the total environment.


St. Louis Meningoencephalitis
Lethargic Encephalitis, Type C
Encephalitis, Viral, St. Louis
Saint Louis Encephalitis
St. Louis Viral Encephalitis
Encephalitis, Saint Louis
St. Louis Encephalitis
Type C Lethargic Encephalitis
Meningoencephalitis, St. Louis
Encephalitis, St. Louis

A viral encephalitis caused by the St. Louis encephalitis virus (ENCEPHALITIS VIRUS, ST. LOUIS), a FLAVIVIRUS. It is transmitted to humans and other vertebrates primarily by mosquitoes of the genus CULEX. The primary animal vectors are wild birds and the disorder is endemic to the midwestern and southeastern United States. Infections may be limited to an influenza-like illness or present as an ASEPTIC MENINGITIS or ENCEPHALITIS. Clinical manifestations of the encephalitic presentation may include SEIZURES, lethargy, MYOCLONUS, focal neurologic signs, COMA, and DEATH. (From Adams et al., Principles of Neurology, 6th ed, p750)


Antipsychotic Agents
Major Tranquilizers
Antipsychotic Effects
Tranquillizing Agents, Major
Tranquilizing Agents, Major
Neuroleptic Agents
Antipsychotic Effect
Antipsychotic Drugs
Antipsychotics
Neuroleptics
Neuroleptic Drugs

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.


Horseback Riding Therapy
Recreational Horseback Riding Therapy
Equine-Assisted Therapy
Hippotherapy
Equine-Assisted Psychotherapy

A treatment strategy that uses the movement of the horse as a treatment tool for the rider who has physical, developmental or other limitations (e.g., cerebral palsy). Typically, a hippotherapy session involves a team of a health professional (e.g., occupational therapist), a horse handler, and the rider. The rhythm of the horse's movement is thought to challenge and influence the rider in improving balance, muscle symmetry, gross motor functions, etc.


Infections, Parvoviridae
Parvoviridae Infections
Infections, Parvovirus
Parvovirus Infections

Virus infections caused by the PARVOVIRIDAE.


Fenazoxine
Nefopam
Nefopam Hydrochloride
Ajan
Acupan
Silentan Nefopam

Non-narcotic analgesic chemically similar to ORPHENADRINE. Its mechanism of action is unclear. It is used for the relief of acute and chronic pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p26)


Illness Days
Sick Days
Disability Leave
Sick Leave

An absence from work permitted because of illness or the number of days per year for which an employer agrees to pay employees who are sick. (Webster's New Collegiate Dictionary, 1981)


Doxepin Hydrochloride, Cis-Trans Isomer Mixture (approximately 1:5)

A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.


Ultrasonography, Endoscopic
Endoscopy, Ultrasonic
Ultrasonic Endoscopy
Endosonography
Endoscopy, Echo
Endoscopic Ultrasonography
Echo-Endoscopy

Ultrasonography of internal organs using an ultrasound transducer sometimes mounted on a fiberoptic endoscope. In endosonography the transducer converts electronic signals into acoustic pulses or continuous waves and acts also as a receiver to detect reflected pulses from within the organ. An audiovisual-electronic interface converts the detected or processed echo signals, which pass through the electronics of the instrument, into a form that the technologist can evaluate. The procedure should not be confused with ENDOSCOPY which employs a special instrument called an endoscope. The "endo-" of endosonography refers to the examination of tissue within hollow organs, with reference to the usual ultrasonography procedure which is performed externally or transcutaneously.


Attachment Site, Bacterial
AttP Attachment Sites
Microbiologic Attachment Sites
Att Attachment Sites
Bacterial Attachment Site
Attachment Sites (Microbiology)
Phage Attachment Sites
AttB Attachment Sites
Bacterial Attachment Sites
Attachment Sites, Bacterial
Microbiologic Attachment Site
Attachment Sites, Microbiological
Attachment Site (Microbiology)

Specific loci on both the bacterial DNA (attB) and the phage DNA (attP) which delineate the sites where recombination takes place between them, as the phage DNA becomes integrated (inserted) into the BACTERIAL DNA during LYSOGENY.


The state of having lost a marital partner by death.


Clips
Clips, Surgical
Clip, Surgical
Hook, Surgical
Scissors, Surgical
Clips, Tantalum
Surgical Hook
Hooks, Surgical
Instrument, Surgical
Surgical Clamp
Surgical Plugs
Plugs, Surgical
Valves, Surgical
Clamp, Surgical
Plug, Surgical
Surgical Instruments
Clamps, Surgical
Surgical Valves
Surgical Clamps
Forceps
Trocar
Surgical Clips
Speculum
Valve, Surgical
Surgical Clip
Surgical Valve
Surgical Hooks
Surgical Scissors
Surgical Plug

Hand-held tools or implements used by health professionals for the performance of surgical tasks.


Surgical Procedures, Culdoscopic
Surgery, Culdoscopic
Culdoscopic Surgery
Culdoscopic Surgical Procedures
Culdoscopy

Endoscopic examination, therapy or surgery of the female pelvic viscera by means of an endoscope introduced into the pelvic cavity through the posterior vaginal fornix.


Evoked Potentials
Potentials, Event-Related
N100 Evoked Potentials
P200 Evoked Potentials
N300 Evoked Potentials
N3 Wave
N400 Evoked Potentials
N2 Wave
N4 Wave
P50 Wave
N1 Wave
Event-Related Potentials
N200 Evoked Potentials
P600 Evoked Potentials
P2 Wave
P50 Evoked Potentials

A negative waveform component of the electrical response that peaks approximately 200 milliseconds after a stimulus.


Fibromatosis Fibromyxoma Fibroma Myxofibroma

A benign tumor of fibrous or fully developed connective tissue.


Lymphocyte-Rich Classical Hodgkin's Lymphoma

Nodular Lymphocyte-Predominant Hodgkin's Lymphoma

A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.


Serotonin 1Dalpha Receptor
5-HT(1D) Receptor
5-HT1Dalpha Receptor
Serotonin 1Dalpha Receptors
Receptor, Serotonin, 5-HT1D
Serotonin 1D Alpha Receptor
5-HT1D Receptor
Receptor, Serotonin 1Dalpha
Receptor, Serotonin 1D
Serotonin 1D Receptor
Serotonin 1D Receptors
5-HT(1Dalpha) Receptor
5-Hydroxytryptamine1D Receptor

A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.


Semantic Memory Disorder
Spatial Memory Disorder
Memory Disorders
Memory Disorder, Spatial
Memory Loss
Memory Deficits
Age-Related Memory Disorders
Memory Disorders, Age-Related
Memory Disorder, Semantic
Retention Disorders, Cognitive

Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.


Endocrinology and Metabolism Specialty
Endocrinology
Metabolism and Endocrinology Specialty

A subspecialty of internal medicine concerned with the metabolism, physiology, and disorders of the ENDOCRINE SYSTEM.


Extracts, Complex
Complex Extracts
Complex Mixtures
Mixtures, Complex
Extracts, Crude
Crude Extracts

Mixtures of many components in inexact proportions, usually natural, such as PLANT EXTRACTS; VENOMS; and MANURE. These are distinguished from DRUG COMBINATIONS which have only a few components in definite proportions.


Two-Item Generalised Anxiety Disorder Scale

Patient Health Questionnaire Anxiety and Depression Scale

A self-administered version of the Primary Care Evaluation of Mental Disorders (PRIME-MD), a diagnostic tool containing modules on multiple mental health disorders including anxiety, alcohol, eating, and somatoform modules. The Patient Health Questionnaire (PHQ-9) is designed specifically for mood/depression scoring each of the 9 DSM-IV criteria based on the mood module from the original PRIME-MD. The Generalized Anxiety Disorder scale (GAD-7) scores 7 common anxiety symptoms.


Psychophysiology
Physiological Psychology
Physiologic Psychology
Psychology, Physiologic
Psychology, Physiological
Mind-Body Relations (Physiology)
Mind-Body Relationship (Physiology)

The study of the physiological basis of human and animal behavior.


Drunk Driving
Drinking and Driving
Driving While Intoxicated
Drunken Driving
Driving Under the Influence

Operating a motor vehicle while impaired by alcohol or other drugs including those prescribed by physicians.


Pulmonary Langerhans Cell Granulomatosis

Langerhans Cell Granulomatosis, Pulmonary

A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.


Sequence Homologs
Sequence Homology
Homologous Sequences
Homologs, Sequence

The degree of similarity between sequences. Studies of AMINO ACID SEQUENCE HOMOLOGY and NUCLEIC ACID SEQUENCE HOMOLOGY provide useful information about the genetic relatedness of genes, gene products, and species.


Hibernation, Artificial
Hibernation
Induced Hibernation

The dormant state in which some warm-blooded animal species pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.


Lawsonia Plant
Lawsonia inermis
Henna Plant

A plant genus of the family LYTHRACEAE that is the source of henna and has cytotoxic activity.