Slender, cylindrical filaments found in the cytoskeleton of plant and animal cells. They are composed of the protein TUBULIN and are influenced by TUBULIN MODULATORS.


Expulsion of a population from a given territory due to religious or ethnic discrimination, political, strategic or ideological considerations, or a combination of these.


A protozoan parasite from Southeast Asia that causes monkey malaria. It is naturally acquired by man in Malaysia and can also be transmitted experimentally to humans.


A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)


The use of silver, usually silver nitrate, as a reagent for producing contrast or coloration in tissue specimens.


Lymphatic Diseases
Lymphatism
Status Lymphaticus

Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.


A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)


Flap Tears
Tibial Meniscus Injuries
Torn Tibial Meniscus
Bucket Handle Tears
Tibial Meniscus Tears

Injuries to the TIBIAL MENISCUS of the leg.


A rather rare metallic element with atomic number 40, atomic weight 91.224, and symbol Zr.


Time interval, or number of non-contraceptive menstrual cycles that it takes for a couple to conceive.


Derivatives of BENZOIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure.


A species of bacterium of the family NOCARDIACEAE, producing pulmonary infections in man.


The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.


A plant genus of the family ZYGOPHYLLACEAE. HARMALINE and other ALKALOIDS, phenylpropanoids, and TRITERPENES have been found in plants of this genus.


A species of gram-positive bacteria in the family Clostridiaceae, used for the industrial production of SOLVENTS.


Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)


Dentofacial Abnormalities
Dentofacial Dyplasia
Dentofacial Deformities

An abnormality of the jaws or teeth affecting the contour of the face. Such abnormality could be acquired or congenital.


A genus of SQUID in the family Loliginidae, superorder DECAPODIFORMES, with a spindle-shaped body. They are well-studied, common inshore squids of the Atlantic and eastern Pacific Oceans, but their various species are taxonomically unresolved.


The quantity of volume or surface area of ORGANELLES.


Systematically organized information on pharmacy.


Immunosuppression (Physiology)
Immune Tolerance

The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.


A plant genus of the family VERBENACEAE. Lippsidoquinone; TRITERPENES; SESQUITERPENES; and THYMOL have been found in this genus. Plant extracts have cytotoxic activity. It is sometimes called Mexican oregano but that confuses it with real oregano (ORIGANUM).


A family of RNA viruses naturally infecting rodents and consisting of one genus (ARENAVIRUS) with two groups: Old World Arenaviruses (ARENAVIRUSES, OLD WORLD) and New World Arenaviruses (ARENAVIRUSES, NEW WORLD). Infection in rodents is persistent and silent. Vertical transmission is through milk-, saliva-, or urine-borne routes. Horizontal transmission to humans, monkeys, and other animals is important.


Oxidoreductases that are specific for the reduction of NITRATES.


A genus of ascomycetous yeast in the family Dipodascaceae, order SACCHAROMYCETALES. It is characterized by asci which have persistent walls and by smooth-walled ascospores. Anamorphs are in the genus GEOTRICHUM.


A genus of the family POXVIRIDAE, subfamily CHORDOPOXVIRINAE, causing tumors in primates. The type species is YABA MONKEY TUMOR VIRUS.


Chemicals administered to patients in order to diagnose or study the pathology of medical conditions, diseases, or syndromes.


The medical use of honey bee products such as BEE VENOM; HONEY; bee pollen; PROPOLIS; and royal jelly.


Neoplasms of the bony orbit and contents except the eyeball.


Communication through a system of conventional vocal symbols.


Tests that evaluate the adrenal glands controlled by pituitary hormones.


Surgical insertion of an appliance for the replacement of areas of the maxilla, mandible, and face. When only portions of the mandible are replaced, it is referred to as MANDIBULAR PROSTHESIS IMPLANTATION.


Barriers based on ethnicity or other group group membership.


Primary headache disorders that show symptoms caused by the activation of the AUTONOMIC NERVOUS SYSTEM of the TRIGEMINAL NERVE. These autonomic features include redness and tearing of the EYE, nasal congestion or discharge, facial SWEATING and other symptoms. Most subgroups show unilateral cranial PAIN.


General term for a group of MALNUTRITION syndromes caused by failure of normal INTESTINAL ABSORPTION of nutrients.


Antibiotic and mycotoxin from Aspergillus niveus and Penicillium citrinum.


Products resulting from the conversion of one language to another.


Nucleic acid regulatory sequences that limit or oppose the action of ENHANCER ELEMENTS and define the boundary between differentially regulated gene loci.


A subspecialty of internal medicine concerned with the anatomy, physiology, and pathology of the kidney.


A mitosporic Trichocomaceae fungal genus that develops fruiting organs resembling a broom. When identified, teleomorphs include EUPENICILLIUM and TALAROMYCES. Several species (but especially PENICILLIUM CHRYSOGENUM) are sources of the antibiotic penicillin.


A collection of heterogenous conditions resulting from defective LIPID METABOLISM and characterized by ADIPOSE TISSUE atrophy. Often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. They include generalized, localized, congenital, and acquired lipodystrophy.


17 beta-Hydroxy-1 alpha-methyl-5 alpha-androstan-3-one. A synthetic steroid with anabolic and androgenic activities.


Water-borne vessels used as HOSPITALS mostly for military purposes during WARFARE.


Personal Expenditures
Financing, Personal

Payment by individuals or their family for health care services which are not covered by a third-party payer, either insurance or medical assistance.


Unstable isotopes of krypton that decay or disintegrate emitting radiation. Kr atoms with atomic weights 74-77, 79, 81, 85, and 87-94 are radioactive krypton isotopes.


A group of cells at the base of a leaf in certain plants that, by rapidly losing water, brings about changes in the position of the leaves. (Concise Dictionary of Biology, 1990)


A systematic process of adapting wild species of animals and plants into new environments often in close association or proximity to humans.


Enzymes that regulate the topology of DNA by actions such as breaking, relaxing, passing, and rejoining strands of DNA in cells. These enzymes are important components of the DNA replication system. They are classified by their substrate specificities. DNA TOPOISOMERASE I enzymes act on a single strand of DNA. DNA TOPOISOMERASE II enzymes act on double strands of DNA.


An increase in the total red cell mass of the blood. (Dorland, 27th ed)


A fungal genus which grows in the epidermis and is the cause of TINEA.


The language and sounds expressed by a child at a particular maturational stage in development.


A genus of FLAVIVIRIDAE, also known as mucosal disease virus group, which is not arthropod-borne. Transmission is by direct and indirect contact, and by transplacental and congenital transmission. Species include BORDER DISEASE VIRUS, bovine viral diarrhea virus (DIARRHEA VIRUS, BOVINE VIRAL), and CLASSICAL SWINE FEVER VIRUS.


An order of nematodes of the subclass SECERNENTEA. Its organisms are characterized by an annulated or smooth cuticle and the absence of caudal glands.


Collaborative process of reaching a decision.


Data processing using paper cards with punched holes that represent data.


An abnormal hemoglobin that results from the substitution of lysine for glutamic acid at position 26 of the beta chain. It is most frequently observed in southeast Asian populations.


Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.


Accumulations of blood in the PERITONEAL CAVITY due to internal HEMORRHAGE.


Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.


Living outdoors as a recreational activity.


The prevention of growth and or spread of unwanted plants.


A plant genus of the family ZINGIBERACEAE. Members contain aculeatin D, beta-sitosterol, and STIGMASTEROL. Some members have been reclassified to ELETTARIA and other ZINGIBERACEAE.


Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.


The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).


A plant genus of the family PROTEACEAE which should not be confused with Protea Beetles (Cetoniini).


A broad approach to appropriate coordination of the entire disease treatment process that often involves shifting away from more expensive inpatient and acute care to areas such as preventive medicine, patient counseling and education, and outpatient care. This concept includes implications of appropriate versus inappropriate therapy on the overall cost and clinical outcome of a particular disease. (From Hosp Pharm 1995 Jul;30(7):596)


A species of parasitic nematode found in the intestine of dogs. Lesions in the brain, liver, eye, kidney, and lung are caused by migrating larvae. In humans, these larvae do not follow normal patterns and may produce visceral larva migrans (LARVA MIGRANS, VISCERAL).


A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.


An order of nematodes of the subclass SECERNENTEA. Characteristics include ventral or caudoventral papillae and an esophagus divided into anterior muscular and posterior glandular parts.


A suborder of ameboid protozoa. Characteristics include subpseudopodia that are more or less finely tipped, occasionally filiform, commonly furcate hyaline, and produced from a broad hyaline lobe. Cysts are usually formed and nuclear division is mesomitotic or metamitotic.


Family of MITES, in the superfamily Sarcoptoidea, order Astigmata. They are slow moving, obligate PARASITES that infect MAMMALS and BIRDS. The species SARCOPTES SCABIEI causes SCABIES.


A genus of IRIDOVIRIDAE comprising small iridescent insect viruses. The infected larvae and purified virus pellets exhibit a blue to purple iridescence.


Activity which reduces the feelings of tension and the effects of STRESS, PHYSIOLOGICAL.


A complex blood group system having pairs of alternate antigens and amorphic genes, but also subject to a dominant independently segregating repressor.


Works about research studies that evaluate interventions or exposures on biomedical or health-related outcomes.  The two main types of clinical studies are interventional studies (clinical trials) and observational studies.


In evolutionary theory, overlapping geographic distribution of diverging species. In sympatric GENETIC SPECIATION, genetic diversion occurs without geographic separation.


A system which emphasizes that experience and behavior contain basic patterns and relationships which cannot be reduced to simpler components; that is, the whole is greater than the sum of its parts.


A personality trait rendering the individual acceptable in social or interpersonal relations. It is related to social acceptance, social approval, popularity, social status, leadership qualities, or any quality making him a socially desirable companion.


A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.


Organic Anion Transporters, Sodium-Dependent

A subclass of ORGANIC ANION TRANSPORTERS whose transport of organic anions is driven either directly or indirectly by a gradient of sodium ions.


A genus of gram-positive, facultatively anaerobic bacteria whose growth is dependent on the presence of a fermentable carbohydrate. No endospores are produced. Its organisms are found in fermenting plant products and are nonpathogenic to plants and animals, including humans.


An element of the rare earth family of metals. It has the atomic symbol Yb, atomic number 70, and atomic weight 173. Ytterbium has been used in lasers and as a portable x-ray source.


A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria that require SERUM; ASCITIC FLUID; or BLOOD for growth. Its organisms inhabit the THROAT; and NASOPHARYNX of wild and laboratory rats and cause one form of RAT-BITE FEVER in man.


Any situation where an animal or human is trained to respond differentially to two stimuli (e.g., approach and avoidance) under reward and punishment conditions and subsequently trained under reversed reward values (i.e., the approach which was previously rewarded is punished and vice versa).


Combination of HEALTH KNOWLEDGE, ATTITUDES, PRACTICE which underlie actions taken by individuals regarding their health.


A species of gram-negative bacteria, in the genus ERWINIA, causing a necrotic disease of plants.


Derivatives of propylamine (the structural formula NH2CH2CH2CH3).


A synthetic glucocorticoid with anti-inflammatory properties.


Autologous skeletal muscle that is wrapped around the heart and electrically stimulated in order to provide mechanical heart assistance. The latissimus dorsi muscle is commonly used to form this ventricle that functions to independently augment cardiac performance by pumping in series with the heart.


Derivatives of ethylenediamine (the structural formula NH2CH2CH2NH2).


A plant genus of the family POLYGALACEAE that contains securiosides and indole alkaloids.


A nerve originating in the lumbar spinal cord (L2 to L4) and traveling through the lumbar plexus to the lower extremity. The obturator nerve provides motor innervation to the adductor muscles of the thigh and cutaneous sensory innervation of the inner thigh.


Histamine Hydrochloride
Histamine
Ceplene
Histamine Dihydrochloride
Peremin

Tradename for histamine dihydrochloride.


Selective renal carbonic anhydrase inhibitor. It may also be of use in certain cases of respiratory failure.


The amount of DNA (or RNA) in one copy of a genome.


Provisions of an insurance policy that require the insured to pay some portion of covered expenses. Several forms of sharing are in use, e.g., deductibles, coinsurance, and copayments. Cost sharing does not refer to or include amounts paid in premiums for the coverage. (From Dictionary of Health Services Management, 2d ed)


A psychological theory based on dimensions or categories used by a given person in describing or explaining the personality and behavior of others or of himself. The basic idea is that different people will use consistently different categories. The theory was formulated in the fifties by George Kelly. Two tests devised by him are the role construct repertory test and the repertory grid test. (From Stuart Sutherland, The International Dictionary of Psychology, 1989)


The process by which organs are kept viable outside of the organism from which they were removed (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).


An order of parasitic EUKARYOTES typically having four to six flagella. True cysts are known in very few species. Trichomonadida were formerly members of the class Zoomastigophora in the old five kingdom paradigm.


A general term collectively applied to tumors associated with the APUD CELLS series, irrespective of their specific identification.


Alkaloids obtained from various plants, especially the deadly nightshade (Atropa belladonna), variety acuminata; atropine, hyoscyamine and scopolamine are classical, specific antimuscarinic agents with many pharmacologic actions; used mainly as antispasmodics.


Recording of change in the size of a part as modified by the circulation in it.


Stable phosphorus atoms that have the same atomic number as the element phosphorus, but differ in atomic weight. P-31 is a stable phosphorus isotope.


A group of compounds that contain a bivalent O-O group, i.e., the oxygen atoms are univalent. They can either be inorganic or organic in nature. Such compounds release atomic (nascent) oxygen readily. Thus they are strong oxidizing agents and fire hazards when in contact with combustible materials, especially under high-temperature conditions. The chief industrial uses of peroxides are as oxidizing agents, bleaching agents, and initiators of polymerization. (From Hawley's Condensed Chemical Dictionary, 11th ed)


The formation of dense connective tissue in the TYMPANIC MEMBRANE that does not necessarily cause or lead to loss of hearing.


INFLAMMATION of the LIVER in non-human animals.


Self-administered health questionnaire developed to obtain details of the medical history as an adjunct to the medical interview. It consists of 195 questions divided into eighteen sections; the first twelve deal with somatic complaints and the last six with mood and feeling patterns. The Index is used also as a personality inventory or in epidemiologic studies.


The 4-aminomethyl form of VITAMIN B 6. During transamination of amino acids, PYRIDOXAL PHOSPHATE is transiently converted into pyridoxamine phosphate.


Painful URINATION. It is often associated with infections of the lower URINARY TRACT.


Diagnostic and Statistical Manual of Mental Disorders

Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)


A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE); dihydrolipoamide acetyltransferase; and LIPOAMIDE DEHYDROGENASE. Pyruvate dehydrogenase complex is subject to three types of control: inhibited by acetyl-CoA and NADH; influenced by the energy state of the cell; and inhibited when a specific serine residue in the pyruvate decarboxylase is phosphorylated by ATP. PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE catalyzes reactivation of the complex. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)


Xanthoma Disseminatum
Histiocytosis, Non-Langerhans-Cell
Reticulohistiocytoma

Group of disorders which feature accumulations of active HISTIOCYTES and LYMPHOCYTES, but where the histiocytes are not LANGERHANS CELLS. The group includes HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; SINUS HISTIOCYTOSIS; xanthogranuloma; reticulohistiocytoma; JUVENILE XANTHOGRANULOMA; xanthoma disseminatum; as well as the lipid storage diseases (SEA-BLUE HISTIOCYTE SYNDROME; and NIEMANN-PICK DISEASES).


A bacterial vaccine for the prevention of brucellosis in man and animal. Brucella abortus vaccine is used for the immunization of cattle, sheep, and goats.


Diseases characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spinal cord. Inclusions of the pathologic protein in neurons and glia, without the presence of AMYLOID, is the major feature of these conditions, thus making these proteinopathies distinct from most other neurogenerative disorders in which protein misfolding leads to brain amyloidosis. Both frontotemporal lobar degeneration and AMYOTROPHIC LATERAL SCLEROSIS exhibit this common method of pathogenesis and thus they may represent two extremes of a continuous clinicopathological spectrum of one disease.


Observable changes of expression in the face in response to emotional stimuli.


Tumor-selective, replication competent VIRUSES that have antineoplastic effects. This is achieved by producing cytotoxicity-enhancing proteins and/or eliciting an antitumor immune response. They are genetically engineered so that they can replicate in CANCER cells but not in normal cells, and are used in ONCOLYTIC VIROTHERAPY.


Caulimoviridae Cavemovirus Petuvirus Solendovirus Soymovirus Rosadnavirus

A family of DNA plant viruses with isometric or bacilliform virions and no envelope. The host ranges of most species are narrow. There are six genera: CAULIMOVIRUS; BADNAVIRUS; Cavemovirus; Soymovirus; Petuvirus; and TUNGROVIRUS.


Drying and inflammation of the conjunctiva as a result of insufficient lacrimal secretion. When found in association with XEROSTOMIA and polyarthritis, it is called SJOGREN'S SYNDROME.


External application of water for therapeutic purposes.


Members of the class of neutral glycosphingolipids. They are the basic units of SPHINGOLIPIDS. They are sphingoids attached via their amino groups to a long chain fatty acyl group. They abnormally accumulate in FABRY DISEASE.


Individuals participating in the health care system for the purpose of receiving therapeutic, diagnostic, or preventive procedures.


Oxidoreductases Acting on Aldehyde or Oxo Group Donors

A broad category of oxidoreductases that either reduce double bonds or oxidize single bonds between OXYGEN and CARBON in organic compounds.


Small organic molecules that act as allosteric activators of the calcium sensing receptor (CaSR) in the PARATHYROID GLANDS and other tissues. They lower the threshold for CaSR activation by extracellular calcium ions and diminish PARATHYROID HORMONE (PTH) release from parathyroid cells.


The turning outward (eversion) of the edge of the eyelid, resulting in the exposure of the palpebral conjunctiva. (Dorland, 27th ed)


The awareness of the spatial properties of objects; includes physical space.


The sum or the stock of words used by a language, a group, or an individual. (From Webster, 3d ed)


Suaeda Chenopodiaceae Kochia Halogeton Salicornia

The goosefoot plant family of the order Caryophyllales, subclass Caryophyllidae, class Magnoliopsida. It includes beets and chard (BETA VULGARIS), as well as SPINACH, and salt tolerant plants.


A status with BODY WEIGHT that is above certain standard of acceptable or desirable weight. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal "over fat".


A plant genus of the family APIACEAE. Members contain THAPSIGARGIN and other guaianolides (SESQUITERPENES, GUAIANOLIDE).


A genus of ascomycetous fungi in the family Nectriaceae, order HYPOCREALES. They are found as saprophytes on decaying wood or parasites of trees. Anamorphs include FUSARIUM and Cylindrocarpon.


The field of nursing care concerned with the promotion, maintenance, and restoration of health.


Edible seeds which contain all components of the seed - germ, bran, and ENDOSPERM.


Derivatives of isocitric acid, a structural isomer of CITRIC ACID, including its salts and esters.


Geminin inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex. It is absent during G1 phase of the CELL CYCLE and accumulates through S, G2,and M phases. It is degraded at the metaphase-anaphase transition by the ANAPHASE-PROMOTING COMPLEX-CYCLOSOME.


An element of the rare earth family of metals. It has the atomic symbol Tm, atomic number 69, and atomic weight 168.93.


The totality of characteristics of reproductive structure, functions, PHENOTYPE, and GENOTYPE, differentiating the MALE from the FEMALE organism.


A group of MYCOTOXINS found in CORN contaminated with FUSARIUM fungus. They are chains of about 20 carbons with acidic ester, acetylamino and sometimes other substituents. They inhibit ceramide synthetase conversion of SPHINGOLIPIDS to CERAMIDES.


A family of gram-negative bacteria in the order Oceanospirillales.


Enediyne aminoglycosides derived from the bacterium MICROMONOSPORA ECHINOSPORA that are used as antineoplastic antibiotics. They bind to DNA in both healthy and tumor cells, resulting in strand scission and cell death.


The artery formed by the union of the right and left vertebral arteries; it runs from the lower to the upper border of the pons, where it bifurcates into the two posterior cerebral arteries.


Observational Studies, Veterinary as Topic

Works about clinical studies in which animal subjects may receive diagnostic, therapeutic, or other types of interventions and where the investigator does not assign subjects  to specific interventions.


Hearing loss in frequencies above 1000 hertz.


A plant family of the order Hamamelidales, subclass Hamamelidae, class Magnoliopsida.


A species of gram-negative, aerobic bacteria that is pathogenic for plants.


The science pertaining to the interrelationship of psychologic phenomena and the individual's response to the physical properties of sound.


The ability to recognize when information is needed and to locate, evaluate, and use the needed information effectively.


Lenograstim
Granocyte
Lenograstim, Component 1
Euprotin
Lenograstim, Component 2

A recombinant granulocyte colony-stimulating factor that is used to treat or prevent NEUTROPENIA in patients receiving myelosuppressive cancer chemotherapy, for the preparation and collection of blood progenitor cells in PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; and in the treatment of severe congenital neutropenia. Component 1 and Component 2 differ by absence or presence of Neu5Ac in 2-6 linkage to GalNAc side chain.


Benzoic acid or benzoic acid esters substituted with one or more bromine atoms.


Treatment with a combination of two types of antiplatelet agents to prevent blood clotting - usually ASPIRIN and another of the PLATELET AGGREGATION INHIBITORS.


Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.


Government Officials
Diplomat
Government Employees


A plant genus of the family ASTERACEAE that contains antifungal plant defensin.


Life Care Centers, Retirement
Housing for the Elderly
Continuing Care Retirement Centers

Housing arrangements for the elderly or aged, intended to foster independent living. The housing may take the form of group homes or small apartments. It is available to the economically self-supporting but the concept includes housing for the elderly with some physical limitations. The concept should be differentiated from HOMES FOR THE AGED which is restricted to long-term geriatric facilities providing supervised medical and nursing services.


A prosthetic appliance for the replacement of areas of the mandible missing or defective as a result of deformity, disease, injury, or surgery.


Infection of ruminants with tapeworms of the genus Moniezia.


A genus of basidiomyceteous fungi in the family POLYPORACEAE found mostly on living trees or dead wood.


A method of stopping internal bleeding or blood flow, or the closure of a wound or body cavity, achieved by applying pressure or introducing an absorbent liquid, gel, or tampon.


Hemolytic anemia due to the ingestion of fava beans or after inhalation of pollen from the Vicia fava plant by persons with glucose-6-phosphate dehydrogenase deficient erythrocytes.


Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.


Solid rather than hollow nanometer-sized rods formed from multiwalled nanotubes.


Indifference to, or rejection of, RELIGION or religious considerations. (From Merriam-Webster's Collegiate Dictionary, 10th ed)


The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.


Skin tests in which the sensitizer is applied to a patch of cotton cloth or gauze held in place for approximately 48-72 hours. It is used for the elicitation of a contact hypersensitivity reaction.


Spider Bites
Arachnidism
Necrotic Arachnidism

The effects, both local and systemic, caused by the bites of SPIDERS.


An irregularly shaped venous space in the dura mater at either side of the sphenoid bone.


Derivatives of methylamine (the structural formula CH3NH2).


A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.


An immunological attack mounted by a graft against the host because of tissue incompatibility when immunologically competent cells are transplanted to an immunologically incompetent host; the resulting clinical picture is that of GRAFT VS HOST DISEASE.


A species of AZORHIZOBIUM which forms nodules on the roots of the tropical legume Sesbania rostrata. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


A measurement of OXYGEN uptake in a sitting, resting person (resting oxygen consumption), varying with age, sex, race, and other factors. In normal adult men, one MET is approximately 3.5 ml O2/kg/min of body weight. Oxygen uptake during activities or work can be measured in METs which can be use to determine health status and exercise prescription.


Medicare Prescription Drug Improvement and Modernization Act of 2003, PL 108-173.


A series of tests used to assess various functions of the eyes.


An intracellular proteinase found in a variety of tissue. It has specificity similar to but narrower than that of pepsin A. The enzyme is involved in catabolism of cartilage and connective tissue. EC 3.4.23.5. (Formerly EC 3.4.4.23).


A condition of metabolic imbalance that is caused by complications of initially feeding a severely malnourished patient too aggressively. Usually occurring within the first 5 days of refeeding, this syndrome is characterized by WATER-ELECTROLYTE IMBALANCE; GLUCOSE INTOLERANCE; CARDIAC ARRHYTHMIAS; and DIARRHEA.


Physiological or psychological effects of periods of work which may be fixed or flexible such as flexitime, work shifts, and rotating shifts.


Abnormal breathing through the mouth, usually associated with obstructive disorders of the nasal passages.


Affective Symptoms
Alexithymia
Emotional Disturbances

Mood or emotional responses dissonant with or inappropriate to the behavior and/or stimulus.


A low-molecular-weight (16,000) iron-free flavoprotein containing one molecule of flavin mononucleotide (FMN) and isolated from bacteria grown on an iron-deficient medium. It can replace ferredoxin in all the electron-transfer functions in which the latter is known to serve in bacterial cells.


A class of ciliate protozoa characterized by a well-developed, conspicuous adoral zone of numerous buccal or peristomial organelles, often extending out onto the body surface.


A ketose sugar that is commonly used in the commercial synthesis of ASCORBIC ACID.


Nutrient blood vessels which supply the walls of large arteries or veins.


The ventral rami of the thoracic nerves from segments T1 through T11. The intercostal nerves supply motor and sensory innervation to the thorax and abdomen. The skin and muscles supplied by a given pair are called, respectively, a dermatome and a myotome.


A synthetic steroid with estrogenic activity.


An order of heavy-bodied, slow-moving, completely aquatic, herbivorous mammals. The body is fusiform, plump, and hairless, except for bristles on the snout. Hindlimbs are absent, the forelimbs are modified to flippers, and the tail is a horizontal fluke. (From Scott, Concise Encyclopedia Biology, 1996)


The clumping together of suspended material resulting from the action of AGGLUTININS.


A legal requirement that designated types of information acquired by professionals or institutions in the course of their work be reported to appropriate authorities.


Infection with nematodes of the genus Setaria. This condition is usually seen in cattle and equines and is of little pathogenic significance, although migration of the worm to the eye may lead to blindness.


A serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.


Percutaneous Aspiration Thrombectomy
Thrombectomy
Aspiration Thrombectomy

Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.


Specialized phagocytic cells of the MONONUCLEAR PHAGOCYTE SYSTEM found on the luminal surface of the hepatic sinusoids. They filter bacteria and small foreign proteins out of the blood, and dispose of worn out red blood cells.


Molecules which contain an atom or a group of atoms exhibiting an unpaired electron spin that can be detected by electron spin resonance spectroscopy and can be bonded to another molecule. (McGraw-Hill Dictionary of Chemical and Technical Terms, 4th ed)


A phylum of anaerobic fungi found in the stomachs of RUMINANTS. These fungi lack mitochondria and reproduce through zoospores.


Unstable isotopes of ruthenium that decay or disintegrate emitting radiation. Ru atoms with atomic weights 93-95, 97, 103, and 105-108 are radioactive ruthenium isotopes.


Infection with protozoa of the genus TRYPANOSOMA.


Serratus Posterior Superior
Serratus Posterior Inferior
Intermediate Back Muscles

Two muscles, the serratus posterior superior and serratus posterior inferior, located in between the deep and the superficial back muscle layers. Their function is to control THORAX movement.


Nanometer-scale wires made of materials that conduct electricity. They can be coated with molecules such as antibodies that will bind to proteins and other substances.


Oxidases that specifically introduce DIOXYGEN-derived oxygen atoms into a variety of organic molecules.


Information relating to itemized coding of procedures and costs associated with healthcare delivery, used as a means for tracking healthcare utilization, patterns of care, and treatment outcomes.


An active blood parasite that is present in practically all domestic animals in Africa, the West Indies, and parts of Central and South America. In Africa, the insect vector is the tsetse fly. In other countries, infection is by mechanical means indicating that the parasites have been introduced to these countries and have been able to maintain themselves in spite of the lack of a suitable intermediate host. It is a cause of nagana, the severity of which depends on the species affected.


A subclass of winged insects belonging to the class Insecta.


Filament or fiber, or the materials generated from them by weaving, embroidery, knitting, crocheting, tufting, or felting such as yarn, thread, cording, rope, netting, lace, or sheets of cloth or fabric.


A plant genus of the family LAMIACEAE that is an ingredient of Banxia Houpu (DRUGS, CHINESE HERBAL).


Hepatocyte nuclear factors are a family of evolutionarily conserved transcription factors that are preferentially expressed in HEPATOCYTES. They play important roles in liver-specific transcription and are critical for CELL DIFFERENTIATION and METABOLISM.


A supergroup (some say phylum) of ameboid EUKARYOTES, comprising ARCHAMOEBAE; LOBOSEA; and MYCETOZOA.


A large family of parasites in the order EIMERIIDA. They cause COCCIDIOSIS in a number of vertebrates including humans.


The muscles of the palate are the glossopalatine, palatoglossus, levator palati(ni), musculus uvulae, palatopharyngeus, and tensor palati(ni).


A species of gram-negative bacteria of the family ACETOBACTERACEAE found in FLOWERS and FRUIT. Cells are ellipsoidal to rod-shaped and straight or slightly curved.


Compounds of silver and proteins used as topical anti-infective agents.


Granulomatous disorders affecting one or more sites in the respiratory tract.


A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.


Oxidoreductases Acting on CH-CH Group Donors

A subclass of enzymes which includes all dehydrogenases acting on carbon-carbon bonds. This enzyme group includes all the enzymes that introduce double bonds into substrates by direct dehydrogenation of carbon-carbon single bonds.


Indoor or outdoor areas designated for the parking of vehicles.


The process of discovering or asserting an objective or intrinsic relation between two objects or concepts; a faculty or power that enables a person to make judgments; the process of bringing to light and asserting the implicit meaning of a concept; a critical evaluation of a person or situation.


The transitional period before and after MENOPAUSE. Perimenopausal symptoms are associated with irregular MENSTRUAL CYCLE and widely fluctuated hormone levels. They may appear 6 years before menopause and subside 2 to 5 years after menopause.


A clinical manifestation consisting of alterations in an individual's weight from his or her norm.


A defense mechanism operating unconsciously, in which the individual attempts to justify or make consciously tolerable, by plausible means, feelings, behavior, and motives that would otherwise be intolerable.


MULTIPLE PREGNANCY with EMBRYO IMPLANTATION occuring at different locations, involving both an intrauterine site and an extrauterine (ECTOPIC PREGNANCY) site.


A family of gram-positive lactic acid-producing bacteria in the order Lactobacillales.


A subspecialty of internal medicine concerned with morphology, physiology, and pathology of the blood and blood-forming tissues.


Communication between animals involving the giving off by one individual of some chemical or physical signal, that, on being received by another, influences its behavior.


A plant genus of the family Costaceae (sometimes classified in Zingiberaceae), order Zingiberales, subclass Zingiberidae, class Liliopsida (monocotyledons). It is a source of SAPONINS and furostanol glycosides.


Student’s unsuccessful attempt at academic achievement or a marked inadequacy in the areas of scholarship or study. This is not underachievement which is performance, usually in school work, poorer than that predicted from aptitude and/or intelligence testing.