Desmoplastic Small Round-Cell Tumor
Desmoplastic Small-Cell Tumor
Desmoplastic Small Round Cell Tumor
Desmoplastic Small Cell Tumor

A rare, aggressive soft tissue sarcoma that primarily affects adolescents and young adults. It is most commonly found in the abdomen.


Exypaque
Nycodenz
Compound 545
Iohexol 350
Omnipaque
Iohexol

An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.


Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).


Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.


Emergency Medical Service Communication Systems

Communication Systems, Emergency Medical Service

The use of communication systems, such as telecommunication, to transmit emergency information to appropriate providers of health services.


Novozir
Dithane Z-78
Zinc Ethylenebis(dithiocarbamate)
Zineb
Cynkotox

An agricultural fungicide of the dithiocarbamate class. It has relatively low toxicity and there is little evidence of human injury from exposure.


The presence of an uncomplimentary base in double-stranded DNA caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES).


Thin-walled sacs or spaces which function as a part of the respiratory system in birds, fishes, insects, and mammals.


Scheuthauer-Marie-Sainton Syndrome
Marie-Sainton Syndrome
Cleidocranial Digital Dysostosis
Cleidocranial Dysplasia
Dysostosis, Cleidocranial
Cleidocranial Dysostosis

Autosomal dominant syndrome in which there is delayed closing of the CRANIAL FONTANELLES; complete or partial absence of the collarbones (CLAVICLES); wide PUBIC SYMPHYSIS; short middle phalanges of the fifth fingers; and dental and vertebral anomalies.


Tibialis Posterior Dysfunction
Tibial Tendon Dysfunction, Posterior
Posterior Tibial Tendon Dysfunction
Posterior Tibial Tendon Insufficiency

A condition characterized by a broad range of progressive disorders ranging from TENOSYNOVITIS to tendon rupture with or without hindfoot collapse to a fixed, rigid, FLATFOOT deformity. Pathologic changes can involve associated tendons, ligaments, joint structures of the ANKLE, hindfoot, and midfoot. Posterior tibial tendon dysfunction is the most common cause of acquired flatfoot deformity in adults.


SURFACE-ACTIVE AGENTS that induce a dispersion of undissolved material throughout a liquid.


Orthopantomography
Panoramic Radiography
Pantomography
Radiography, Panoramic

Extraoral body-section radiography depicting an entire maxilla, or both maxilla and mandible, on a single film.


A site on an enzyme which upon binding of a modulator, causes the enzyme to undergo a conformational change that may alter its catalytic or binding properties.


Tobacco Use
Tobacco Chewing
Tobacco Consumption

Use of TOBACCO (Nicotiana tabacum L) and TOBACCO PRODUCTS.


Oncogene Protein
Oncogene Product
Oncogene Products
Oncoproteins
Oncogene Proteins

Proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and another gene (ONCOGENE PROTEINS, FUSION).


Administration, Library
Library Administration

Planning, organizing, staffing, direction, and control of libraries.


A subclass of ubiquitously-expressed lamins having an acidic isoelectric point. They are found to remain bound to nuclear membranes during mitosis.


Alcohol-Induced Korsakoff Syndrome
Alcoholic Korsakoff Syndrome
Alcoholic Wernicke-Korsakoff Syndrome

A neurological disorder characterized by inattentiveness and the inability to form short term memories. It is caused by THIAMINE DEFICIENCY due to chronic ALCOHOLISM.


Cross Linking Reagents
Bifunctional Reagents
Cross-Linking Reagents
Crosslinking Reagents

Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.


Inovirus
Filamentous Bacteriophages
Bacteriophages, Filamentous

A genus of filamentous bacteriophages of the family INOVIRIDAE. Organisms of this genus infect enterobacteria, PSEUDOMONAS; VIBRIO; and XANTHOMONAS.


Insecticide-Treated Bed Nets
Insecticide-Treated Bednets
Treated Mosquito Net

Lightweight meshwork fabric made of cotton, silk, polyester, nylon (polyamides), or other material impregnated with insecticide, having openings too small to allow entry of mosquitoes or other insects, thereby offering protection against insect bite and insect-borne diseases.


Proteolysis
Protein Digestion
Protein Degradation

Cleavage of proteins into smaller peptides or amino acids either by PROTEASES or non-enzymatically (e.g., Hydrolysis). It does not include Protein Processing, Post-Translational.


Employer Health Costs
Health Costs, Employer

That portion of total HEALTH CARE COSTS borne by an individual's or group's employing organization.


Veterinary Education
Education, Veterinary

Use for general articles concerning veterinary medical education.


Tumor Virus Infections
Papilloma, Shope
Fibroma, Shope
Infections, Tumor Virus

Infections produced by oncogenic viruses. The infections caused by DNA viruses are less numerous but more diverse than those caused by the RNA oncogenic viruses.


Laryngospasm
Laryngismus
Laryngeal Spasm

A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration.


Spermatic Cord Torsion
Testicular Torsion
Torsion Of Testicular Cord

The twisting of the SPERMATIC CORD due to an anatomical abnormality that left the TESTIS mobile and dangling in the SCROTUM. The initial effect of testicular torsion is obstruction of venous return. Depending on the duration and degree of cord rotation, testicular symptoms range from EDEMA to interrupted arterial flow and testicular pain. If blood flow to testis is absent for 4 to 6 h, SPERMATOGENESIS may be permanently lost.


Electrophoresis, Disc
Electrophoresis, Disk

Electrophoresis in which discontinuities in both the voltage and pH gradients are introduced by using buffers of different composition and pH in the different parts of the gel column. The term 'disc' was originally used as an abbreviation for 'discontinuous' referring to the buffers employed, and does not have anything to do with the shape of the separated zones.


Malate Condensing Enzyme
Malate Synthetase
Glyoxylate Transacetylase
Malate Synthase

An important enzyme in the glyoxylic acid cycle which reversibly catalyzes the synthesis of L-malate from acetyl-CoA and glyoxylate. This enzyme was formerly listed as EC 4.1.3.2.


Ischemic Postconditioning
Ischemic Post-Conditioning

The application of repeated, brief periods of vascular occlusion at the onset of REPERFUSION to reduce REPERFUSION INJURY that follows a prolonged ischemic event. The techniques are similar to ISCHEMIC PRECONDITIONING but the time of application is after the ischemic event instead of before.


Pulmonary Adenomatosis
Adenomatosis, Pulmonary

A neoplastic disease in which the alveoli and distal bronchi are filled with mucus and mucus-secreting columnar epithelial cells. It is characterized by abundant, extremely tenacious sputum, chills, fever, cough, dyspnea, and pleuritic pain. (Stedman, 25th ed)


Poly(Mannuronic Acid)
Polymannuronic Acid
Alginic Acid
Polymannuronic-Guluronic Acid

A polysaccharide and linear copolymer, consisting mainly of beta-1,4-linked D-mannuronic acid and alpha-1,4-linked L-glucuronic acid, that occurs in marine algae such as LAMINARIA, and in BIOFILMS produced by PSEUDOMONAS AERUGINOSA.


Non-Neuronal Cholinergic System
Nonneuronal Cholinergic System

The system of ACETYLCHOLINE-synthesizing enzymes, transporters, receptors and degrading enzymes that characterize non-neuronal cholinergic cells such as airway and skin EPITHELIAL CELLS.


Endurance, Physical
Physical Endurance
Physical Stamina
Stamina, Physical

The time span between the beginning of physical activity by an individual and the termination because of exhaustion.


Cholestasis, Extrahepatic
Bile Duct Obstruction, Extrahepatic
Biliary Stasis, Extrahepatic
Extrahepatic Cholestasis

Impairment of bile flow in the large BILE DUCTS by mechanical obstruction or stricture due to benign or malignant processes.


Forced expiratory effort against a closed GLOTTIS.


A species of the true toads, Bufonidae, found in South America.


Sarcosomes
Mitochondria, Muscle
Mitochondrion, Muscle

Mitochondria of skeletal and smooth muscle. It does not include myocardial mitochondria for which MITOCHONDRIA, HEART is available.


Sinus Arrest, Cardiac
Cardiac Sinus Pause
Cardiac Sinus Arrest

The omission of atrial activation that is caused by transient cessation of impulse generation at the SINOATRIAL NODE. It is characterized by a prolonged pause without P wave in an ELECTROCARDIOGRAM. Sinus arrest has been associated with sleep apnea (REM SLEEP-RELATED SINUS ARREST).


Stimulation, Electric
Electric Stimulation
Electrical Stimulation

Use of electric potential or currents to elicit biological responses.


Persistent Hyperplastic Primary Vitreous

A developmental ocular anomaly in which the primary VITREOUS BODY and its surrounding hyaloid vasculature failed to regress. It is usually unilateral and characterized by CATARACT; MICROPHTHALMOS (small eyeballs), and retrolenticular fibrovascular tissue. (from Yanoff: Ophthalmology, 2nd ed.)


Dopamine Antagonists
Antagonists, Dopamine
Dopamine Receptor Antagonists
Dopamine Blockers
Antagonists, Dopaminergic
Antagonists, Dopamine Receptor
Dopaminergic Antagonists

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.


Sleep Bruxism, Adult
Sleep-Related Bruxism
Bruxism, Nocturnal
Sleep Bruxism
Nocturnal Teeth Grinding Disorder
Sleep Bruxism, Childhood
Teeth Grinding Disorder, Nocturnal

A sleep disorder characterized by grinding and clenching of the teeth and forceful lateral or protrusive jaw movements. Sleep bruxism may be associated with TOOTH INJURIES; TEMPOROMANDIBULAR JOINT DISORDERS; sleep disturbances; and other conditions.


Evipan
Sodium Hexobarbital
Hexobarbital
Hexenal
Hexobarbitone

A barbiturate that is effective as a hypnotic and sedative.


Administration, Intranasal
Intranasal Administration
Administration, Nasal
Drug Administration, Intranasal
Intranasal Drug Administration
Administration, Intranasal Drug

Delivery of medications through the nasal mucosa.


Medical devices which substitute for a nervous system function by electrically stimulating the nerves directly and monitoring the response to the electrical stimulation.


Tumor Necrosis Factor (Ligand) Superfamily, Member 9

Tumor Necrosis Factor Ligand Superfamily Member 9

A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.


A strain of Murine leukemia virus (LEUKEMIA VIRUS, MURINE) isolated from radiation-induced lymphomas in C57BL mice. It is leukemogenic, thymotrophic, can be transmitted vertically, and replicates only in vivo.


After Hours Care
After-Hours Care
Out-of-Hours Medical Care
Practitioner Cooperative

Arrangements to provide healthcare after usual office hours.


Marine fish and shellfish used as food or suitable for food. (Webster, 3d ed) SHELLFISH and FISH PRODUCTS are more specific types of SEAFOOD.


BRL 14777
Relif
Apo-Nabumetone
Mebutan
Nabucox
Gen-Nabumetone
Rhoxal-nabumetone
Nabumeton
Relifex
Nabumetone
4-(6-Methoxy-2-naphthyl)-2-butanone
Relafen
Arthraxan
Listran

A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.


Primary Systemic Amyloidosis
Immunoglobulin Light-chain Amyloidosis
AL Amyloidosis
Amyloidosis, Immunoglobulin Light-chain
Primary Amyloidosis
Amyloidosis, Primary

A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.


Decortication, Cerebral Cortex
Cerebral Cortex Decortication
Cerebral Decortication

Partial or total removal, ablation, or destruction of the cerebral cortex; may be chemical. It is not used with animals that do not possess a cortex, i.e., it is used only with mammals.


The study of CHEMICAL PHENOMENA and processes in terms of the underlying PHYSICAL PHENOMENA and processes.


A family of ark shell mollusks, in the class BIVALVIA. They have soft bodies with platelike GILLS enclosed within two shells hinged together.


Ca(2+)-Transporting ATPase
Calcium-ATPase
ATPase, Calcium
Ca2+ ATPase
Adenosinetriphosphatase, Calcium
Calcium-Transporting ATPases
Calcium ATPase
Calcium Adenosinetriphosphatase
Adenosine Triphosphatase, Calcium

Cation-transporting proteins that utilize the energy of ATP hydrolysis for the transport of CALCIUM. They differ from CALCIUM CHANNELS which allow calcium to pass through a membrane without the use of energy.


TP Receptor
Thromboxane Receptor
TP Receptors
Thromboxane Receptors
Receptors, Thromboxanes
Receptors, Thromboxane

Cell surface proteins that bind THROMBOXANES with high affinity and trigger intracellular changes influencing the behavior of cells. Some thromboxane receptors act via the inositol phosphate and diacylglycerol second messenger systems.


Mechanistic Target of Rapamycin Complex 2

A multiprotein complex consisting of mTOR KINASE; MLST8 PROTEIN;  rapamycin-insensitive companion of mTOR protein (RICTOR PROTEIN); and PRR5 (proline-rich protein 5). Like mTORC1, it also regulates cell growth and proliferation in response to growth factors but may not be as sensitive to nutrient availability and is insensitive to SIROLIMUS. In contrast to mTORC1, it can regulate the ACTIN CYTOSKELETON through RHO GTPASES to promote the formation of STRESS FIBERS. The mTORC2 complex also plays a critical role in AKT1 PROTEIN KINASE phosphorylation and activation.


Environmental Carcinogens
Carcinogens, Environmental

Carcinogenic substances that are found in the environment.


An anabolic steroid with some progestational activity and little androgenic effect.


Psychological Dependency
Dependency, Psychology
Dependency, Psychological
Psychological Dependence
Dependency Burden

The tendency of an individual or individuals to rely on others for advice, guidance, or support.


Anterior pituitary cells that produce ADRENOCORTICOTROPHIC HORMONE.


A family of gram-negative bacteria, in the phylum FIRMICUTES.


Services, Technical Library
Library Services Technical
Technical Library Services
Services, Library Technical
Technical Services Library
Library Technical Services

Acquisition, organization, and preparation of library materials for use, including selection, weeding, cataloging, classification, and preservation.


Postherpetic Neuralgia
Neuralgia, Postherpetic

Pain in nerves, frequently involving facial SKIN, resulting from the activation the latent varicella-zoster virus (HERPESVIRUS 3, HUMAN). The two forms of the condition preceding the pain are HERPES ZOSTER OTICUS; and HERPES ZOSTER OPHTHALMICUS. Following the healing of the rashes and blisters, the pain sometimes persists.


TFII Transcription Factors
Transcription Factors, TFII

The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme.


Technology in which images of virtual objects and/or other digital information are superimposed over the real time view of the physical objects providing a composite view with guides for carrying out a task with or on the physical objects.


N3 Sleep
Delta Sleep
Deep Sleep
Sleep, Slow-Wave
NREM Stage 3
Slow-Wave Sleep

A stage of sleep characterized by synchronized wave activity as observed in the ELECTROENCEPHALOGRAM; the waves exhibit a frequency of 0.5 to 2 Hz, and a peak-to-peak amplitude greater than 75 microvolts.


National Center for Complementary and Integrative Health (U.S.)

The mission of NCCIH is to define, through rigorous scientific investigation, the usefulness and safety of complementary and integrative health interventions and their roles in improving health and health care. The Center was established in 1999 and was known as NCCAM National Center of Complementary and Alternative Medicine until 2015.


Biogenic Polyamines
Polyamines, Biogenic

Biogenic amines having more than one amine group. These are long-chain aliphatic compounds that contain multiple amino and/or imino groups. Because of the linear arrangement of positive charge on these molecules, polyamines bind electrostatically to ribosomes, DNA, and RNA.


Immunology, Allergy
Allergy, Immunology
Immunology and Allergy
Allergy and Immunology
Allergy Specialty
Immunology

A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder.


Ebolavirus Vaccines
Ebola Vaccines
Ebola Virus Vaccines
Ebolavirus Vaccine

Vaccines or candidate vaccines used to prevent EBOLA HEMORRHAGIC FEVER.


DEFICIENS is a homeotic gene involved in the genetic control of Antirrhinum majus flower development. Its protein is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.


TFF2 Protein
TFF2 Peptide
Trefoil Factor-2

A 106 amino acid (12 kDa) trefoil factor that contains two trefoil domains and associates with MUCIN-6. It is expressed in the GASTROINTESTINAL TRACT by cells of BRUNNER GLANDS; PYLORIC GLANDS and mucous neck cells. It inhibits GASTROINTESTINAL MOTILITY and GASTRIC ACID secretion and may help maintain the structural integrity of gastric mucus.


Dihydro beta Erythroidine
Dihydro-beta-Erythroidine

Dihydro analog of beta-erythroidine, which is isolated from the seeds and other plant parts of Erythrina sp. Leguminosae. It is an alkaloid with curarimimetic properties.


Traumatic Dental Occlusion
Occlusion, Dental, Traumatic
Occlusion, Traumatic Dental
Dental Occlusion, Traumatic

An occlusion resulting in overstrain and injury to teeth, periodontal tissue, or other oral structures.


Ternary Complex Transcription Factors
Ternary Complex Factors
Ternary Complex Proteins

A subclass of c-ets proto-oncogene proteins that were first described by their property of binding to DNA when associated with other regulatory proteins such as SERUM RESPONSE FACTOR. They contain an amino-terminal ets domain that binds to DNA along with centrally located SERUM RESPONSE FACTOR interacting domain, and carboxy-terminal map kinase activation domains. They play an important role in transcriptional regulation by INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.


beta-Globins
beta-Globin
Non-alpha Globin Chain, Unspecified

Members of the beta-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 11. They include epsilon-globin, gamma-globin, delta-globin and beta-globin. There is also a pseudogene of beta (theta-beta) in the gene cluster. Adult HEMOGLOBIN is comprised of two ALPHA-GLOBIN chains and two beta-globin chains.


A species of virus (unassigned to a genus) in the family FLAVIVIRIDAE. It is genetically heterogeneous, of human origin, and transmitted by blood or blood products. Despite its alternate name (Hepatitis G virus), its pathogenicity remains controversial.


Nuclear Microscope Analysis
Nuclear Microscopy
Scanning Nuclear Microprobe Analysis

A method of simultaneously imaging and measuring elements at the submicron level. Nuclear microscopy uses a focused high-energy ion beam of PROTONS and ALPHA PARTICLES (a nuclear microprobe) to interact with the sample. The resulting emitted radiations are analyzed by a group of techniques simultaneously: PARTICLE INDUCED X RAY EMISSION SPECTROMETRY for minor and trace element identification; Rutherford Backscattering Spectroscopy to assess sample thickness and bulk elements such as carbon, hydrogen, oxygen, and nitrogen; and Scanning Transmission Ion Microscopy to assess sample structure and density.


c-pim-1 Protein
Proto-Oncogene Protein c-pim-1
Proto-Oncogene Protein pim-1
pim-1 Proto-Oncogene Protein
Proto-Oncogene Proteins c-pim-1
Pim-1 Kinase

Serine-threonine protein kinases that relay signals from CYTOKINE RECEPTORS and are involved in control of CELL GROWTH PROCESSES; CELL DIFFERENTIATION; and APOPTOSIS.


Hemoglobin-C Disease
Hemoglobin C Disease

A disease characterized by compensated hemolysis with a normal hemoglobin level or a mild to moderate anemia. There may be intermittent abdominal discomfort, splenomegaly, and slight jaundice.


Dihydroorotate Oxidase
Dihydro-Orotate Oxidase

An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FLAVIN MONONUCLEOTIDE as well as iron-sulfur centers. EC 1.3.3.1.


Diet Records
Dietary Records
Food Diaries

Records of nutrient intake over a specific period of time, usually kept by the patient.


A family of winged insects of the suborder HETEROPTERA, called assassin bugs, because most prey on other insects. However one subfamily, TRIATOMINAE, attacks humans and other vertebrates and transmits Chagas disease.


A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.


BALB C Mice, Inbred
BALB C Mouse, Inbred
Inbred BALB C Mouse
Mouse, BALB C
Mice, Inbred BALB C
Inbred BALB C Mice
Mice, BALB C
Mouse, Inbred BALB C

An inbred strain of mouse that is widely used in IMMUNOLOGY studies and cancer research.


Sulfaisodimidine
Sulfisomidine Sodium
Aristamid Augentropfen
Sulfisomidine
Elkosin
Sulphasomidine
Aristamid Augensalbe


Cholinergic Agonists, Muscarinic
Cholinergic Muscarinic Agonists
Muscarinic Agonist
Cholinergic Agonist, Muscarinic
Muscarinic Agonists

Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.


Large woodland game BIRDS in the subfamily Meleagridinae, family Phasianidae, order GALLIFORMES. Formerly they were considered a distinct family, Melegrididae.


Complement C3d Fragment
Complement 3d
Complement Component 3d
C3d Complement
Complement C3d

A 302-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactivated (iC3b) and its alpha chain is cleaved by COMPLEMENT FACTOR I into C3c, and C3dg (955-1303) in the presence COMPLEMENT FACTOR H. Serum proteases further degrade C3dg into C3d (1002-1303) and C3g (955-1001).


Deep Sea Vents
Black Smoker Vents
Hydrothermal Vents

Hot springs on the ocean floor. They are commonly found near volcanically active places such as mid-oceanic ridges.


Multiple Chronic Conditions
Multiple Chronic Medical Conditions
Multiple Chronic Illnesses
Multiple Chronic Health Conditions

Two or more concurrent chronic physical, mental, or behavioral health problems in an individual.


Renal Nutcracker Syndrome
Renal Nutcracker Phenomenon
Renal Vein Entrapment Syndrome

Left RENAL VEIN compression between the AORTA, ABDOMINAL and the SUPERIOR MESENTERIC ARTERY. Variable symptoms include HYPERTENSION, RENOVASCULAR; HEMATURIA; and VARICOSE VEINS.


Oils which evaporate readily. The volatile oils occur in aromatic plants, to which they give odor and other characteristics. Most volatile oils consist of a mixture of two or more TERPENES or of a mixture of an eleoptene (the more volatile constituent of a volatile oil) with a stearopten (the more solid constituent). The synonym essential oils refers to the essence of a plant, as its perfume or scent, and not to its indispensability.


Diseases of domestic and wild horses of the species Equus caballus.


MPL Ligand Receptor
Receptors, Thrombopoietin
Antigens, CD110
Thrombopoietin Receptors
Thrombopoietin Receptor
CD110 Antigens

Cell surface receptors that are specific for THROMBOPOIETIN. They contain two central FIBRONECTIN TYPE III DOMAINS and signal through interaction with JANUS KINASES such as JANUS KINASE 2.


H1 Receptors
Receptors, Histamine H1
Receptors, H1
Histamine H1 Receptors
Histamine H1 Receptor

A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamine H1 receptors operate through the inositol phosphate/diacylglycerol second messenger system. Among the many responses mediated by these receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis. (From Biochem Soc Trans 1992 Feb;20(1):122-5)


A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes.


Technique, Cardiovascular Diagnostic
Cardiovascular Diagnostic Technic
Technic, Cardiovascular Diagnostic
Diagnostic Techniques, Cardiovascular
Cardiovascular Diagnostic Technique
Diagnostic Technics, Cardiovascular
Diagnostic Technic, Cardiovascular
Technics, Cardiovascular Diagnostic
Diagnostic Technique, Cardiovascular
Cardiovascular Diagnostic Technics
Techniques, Cardiovascular Diagnostic
Cardiovascular Diagnostic Techniques

Methods and procedures for the diagnosis of diseases or dysfunction of the cardiovascular system or its organs or demonstration of their physiological processes.


Aldosterone Receptor Antagonists
Mineralocorticoid Receptor Antagonists
Aldosterone Antagonists
Mineralocorticoid Antagonists

Drugs that bind to and block the activation of MINERALOCORTICOID RECEPTORS by MINERALOCORTICOIDS such as ALDOSTERONE.


Phosphofructokinase-1, Muscle Type
Phosphofructo-1-kinase Isozyme A
6-Phosphofructokinase, Muscle Type

An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.


FeLV
Leukemia Virus, Feline
Cat Leukemia Virus
Feline Leukemia Virus
Feline Lymphoma Virus

A species of GAMMARETROVIRUS causing leukemia, lymphosarcoma, immune deficiency, or other degenerative diseases in cats. Several cellular oncogenes confer on FeLV the ability to induce sarcomas (see also SARCOMA VIRUSES, FELINE).


Methyl-CpG-Binding Protein 2
MeCP2 Protein

A DNA-binding protein that interacts with methylated CPG ISLANDS. It plays a role in repressing GENETIC TRANSCRIPTION and is frequently mutated in RETT SYNDROME.


Finite Element Analysis
Analysis, Finite Element

A computer based method of simulating or analyzing the behavior of structures or components.


Sex Chromosome Abnormalities
Sex Chromosome Aberrations
Abnormalities, Sex Chromosome
Chromosome Abnormalities, Sex

Abnormal number or structure of the SEX CHROMOSOMES. Some sex chromosome aberrations are associated with SEX CHROMOSOME DISORDERS and SEX CHROMOSOME DISORDERS OF SEX DEVELOPMENT.


Senescent Cell-Derived Inhibitor Protein 1

Cyclin-Dependent Kinase Inhibitor 1A Protein

A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3.


MMR Vaccine
Trimovax
Measles-Mumps-Rubella Vaccine
Virivac
Mumps-Measles-Rubella Vaccine
Triviraten Berna
Priorix
Measles, Mumps, Rubella Vaccine
Pluserix

A combined vaccine used to prevent MEASLES; MUMPS; and RUBELLA.


Periodic Paralysis, Familial
Paralyses, Familial Periodic
Normokalemic Periodic Paralysis
Familial Periodic Paralysis

A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481)


Non-medical support services, such as food preparation and bathing, given by trained personnel to disabled, sick or convalescent individuals in their home.


Pinworm Infection
Oxyuris vermicularis Infection
Enterobiasis
Infection, Oxyuris vermicularis
Infection, Enterobius vermicularis
Enterobius vermicularis Infection

Infection with nematodes of the genus ENTEROBIUS; E. vermicularis, the pinworm of man, causes a crawling sensation and pruritus. This condition results in scratching the area, occasionally causing scarification.


Postcoital Contraceptives
Contraceptives, Postcoital
Contraceptives, Post-Coital
Contraceptive Agents, Post-Coital
Contraceptive Agents, Postcoital
Emergency Contraceptives
Morning-After Pill

High doses of contraceptive substances that can be taken before, the morning after, or up to five days after the unprotected vaginal intercourse.


Cardiac Catheter
Heart Catheters
Cardiac Catheters
Intracardiac Catheters

Catheters inserted into various locations within the heart for diagnostic or therapeutic purposes.


Secretoglobin, Family 1A, Member 1
Clara Cell-Specific Protein
Uteroglobin
Blastokinin
Clara Cell Secretory Protein

A steroid-inducible protein that was originally identified in uterine fluid. It is a secreted homodimeric protein with identical 70-amino acid subunits that are joined in an antiparallel orientation by two disulfide bridges. A variety of activities are associated with uteroglobin including the sequestering of hydrophobic ligands and the inhibition of SECRETORY PHOSPHOLIPASE A2.


Test Preparation
Test Taking Skills
Study Skills
Test-Taking
Test Taking Strategies
Test Wiseness

Skills and strategies, unrelated to the traits a test is intended to measure, that may increase test takers' scores -- may include the effects of coaching or experience in taking tests. (ERIC Thesaurus)


Societies, Nursing
Society, Nursing
Nursing Society
Nursing Societies

Societies whose membership is limited to nurses.


A genus of the family PARAMYXOVIRIDAE (subfamily PARAMYXOVIRINAE) where the virions of most members have hemagglutinin but not neuraminidase activity. All members produce both cytoplasmic and intranuclear inclusion bodies. MEASLES VIRUS is the type species.


Infection with tapeworms of the genus Diphyllobothrium.


Positively charged atoms, radicals or groups of atoms with a valence of plus 2, which travel to the cathode or negative pole during electrolysis.


Receptors, Transforming Growth Factor beta

Transforming Growth Factor beta Receptors

Cell-surface proteins that bind transforming growth factor beta and trigger changes influencing the behavior of cells. Two types of transforming growth factor receptors have been recognized. They differ in affinity for different members of the transforming growth factor beta family and in cellular mechanisms of action.


Bertielliasis
Tapeworm Infection
Raillietiniasis
Dipylidiasis
Cenuriasis
Coenuriasis
Cestode Infections

Infections with true tapeworms of the helminth subclass CESTODA.


Fees, Dental
Dental Fee
Fee, Dental
Dental Fees

Amounts charged to the patient as payer for dental services.


N-Terminal Acetyltransferase Type B
NatB N-Terminal Acetyltransferase
N-Terminal Acetyltransferase B

An N-terminal acetyltransferase subtype that consists of the Naa20p catalytic subunit and the Naa25p auxiliary subunit. The structure of this enzyme is conserved between YEASTS and HUMAN. It has specificity for the N-terminal METHIONINE of peptides where the next amino acid in the chain is either ASPARTATE; GLUTAMATE; ASPARAGINE; or GLUTAMINE.


Magnesium Hydroxide
Magnesium Hydroxide (Mg(OH)4)
Magnesium Hydrate
Brucite

An inorganic compound that occurs in nature as the mineral brucite. It acts as an antacid with cathartic effects.


Diaphragmatic Hernia, Traumatic
Hernia, Diaphragmatic, Traumatic

The type of DIAPHRAGMATIC HERNIA caused by TRAUMA or injury, usually to the ABDOMEN.


Diagnostic Techniques, Digestive System
Digestive System Diagnostic Technics
Diagnostic Technique, Digestive System
Techniques, Digestive System Diagnostic
Digestive System Diagnostic Techniques
Technic, Digestive System Diagnostic
Diagnostic Technic, Digestive System
Digestive System Diagnostic Technique
Digestive System Diagnostic Technic
Diagnostic Technics, Digestive System
Technique, Digestive System Diagnostic
Technics, Digestive System Diagnostic

Methods and procedures for the diagnosis of diseases or dysfunction of the digestive system or its organs or demonstration of their physiological processes.


Heparinase
Heparinase I
Neutralase
Heparin Eliminase
Heparin Lyase

An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. (From Enzyme Nomenclature, 1992) EC 4.2.2.7.


A benzazepine derivative that functions as an ALPHA4-BETA2 NICOTINIC RECEPTOR partial agonist. It is used for SMOKING CESSATION.


Cytoplasmic vesicles formed when COATED VESICLES shed their CLATHRIN coat. Endosomes internalize macromolecules bound by receptors on the cell surface.


The tip or terminal end of the root of a tooth. (Jablonski, Dictionary of Dentistry, 1992, p62)


Nuclear Receptor Subfamily 4, Group A, Member 1

An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene family. It was originally identified in NERVE CELLS and may play a role in mediation of NERVE GROWTH FACTOR-induced CELL DIFFERENTIATION. However, several other functions have been attributed to this protein including the positive and negative regulation of APOPTOSIS.


Space Closure, Orthodontic
Orthodontic Space Closure

Therapeutic closure of spaces caused by the extraction of teeth, the congenital absence of teeth, or the excessive space between teeth.


The capability of producing eggs (OVA) from which young are hatched outside the body. While mostly referring to nonmammalian species, this does include MAMMALS of the order MONOTREMATA.


Monomethylglycine Dehydrogenase
Sarcosine Dehydrogenase
Sarcosine N-Demethylase

A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.


Positron-Emission Tomography
PET Scan
Tomography, Positron-Emission

An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.


A subtype of caspases that contain long pro-domain regions that regulate the activation of the enzyme. The pro-domain regions contain protein-protein interaction motifs that can interact with specific signaling adaptor proteins such as DEATH DOMAIN RECEPTORS; DED SIGNALING ADAPTOR PROTEINS; and CARD SIGNALING ADAPTOR PROTEINS. Once activated, the initiator caspases can activate other caspases such as the EFFECTOR CASPASES.


An outward slant of the thigh in which the knees are wide apart and the ankles close together. Genu varum can develop due to skeletal and joint dysplasia (e.g., OSTEOARTHRITIS; Blount's disease); and malnutrition (e.g., RICKETS; FLUORIDE POISONING).


A highly contagious infectious disease caused by MORBILLIVIRUS, common among children but also seen in the nonimmune of any age, in which the virus enters the respiratory tract via droplet nuclei and multiplies in the epithelial cells, spreading throughout the MONONUCLEAR PHAGOCYTE SYSTEM.


The property of TEETH to permit passage of light, heat, gases, liquids, metabolites, mineral ions and other substances. It does not include the penetration of the teeth by microorganisms.


Neanderthals
Neandertals
Homo sapiens neanderthalensis
Neanderthal Man
Homo neanderthalensis

Common name for an extinct species of the Homo genus. Fossils have been found in Europe and Asia. Genetic evidence suggests that limited interbreeding with modern HUMANS (Homo sapiens) took place.


An arbovirus in the FLAVIVIRUS genus of the family FLAVIVIRIDAE. Originally isolated in the Zika Forest of UGANDA it has been introduced to Asia and the Americas.


A six-member ring deoxysugar with the chemical formula C6H12O5. It lacks a hydroxyl group on the carbon at position 6 of the molecule.


Arthroplasty, Replacement, Finger
Finger Replacement Arthroplasty

Partial or total replacement of one or more FINGERS, or a FINGER JOINT.


Vaginal Births after Cesarean
Vaginal Birth after Cesarean
Vaginal Birth after Cesareans

Delivery of an infant through the vagina in a female who has had a prior cesarean section.


HSP40 Heat-Shock Proteins
Heat Shock Protein 40 Family
HSP40 Proteins
HSP40 Protein Family
DnaJ Proteins
Heat-Shock Protein 40
Heat-Shock Proteins 40

A family of heat-shock proteins that contain a 70 amino-acid consensus sequence known as the J domain. The J domain of HSP40 heat shock proteins interacts with HSP70 HEAT-SHOCK PROTEINS. HSP40 heat-shock proteins play a role in regulating the ADENOSINE TRIPHOSPHATASES activity of HSP70 heat-shock proteins.


Ortoton
Methocarbamol
Lumirelax
Parabaxin
Guaiphenesin Carbamate
Robaxin

A centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1206)


Genes, vpr
vpr Genes
Genes, R
vpr Gene
Genes, rap

DNA sequences that form the coding region for a trans-activator protein that specifies rapid growth in human immunodeficiency virus (HIV). vpr is short for viral protein R, where R is undefined.


Treatment for individuals with speech defects and disorders that involves counseling and use of various exercises and aids to help the development of new speech habits.


Erythrocyte Sedimentation Rate
Blood Sedimentation
Erythrocyte Sedimentation

Measurement of rate of settling of erythrocytes in anticoagulated blood.


Out-Toeing
Metatarsus Valgus
Metatarsal Valgus
Toeing Out

A foot anomaly in which the forefoot is angled outward relative to the hindfoot.


Chelating agent and inhibitor of cellular respiration.


Genome, Plastid
Plastid Genomes
Plastid Genome

The genetic complement of PLASTIDS as represented in their DNA.


Chronic Illness
Chronically Ill
Chronic Disease

Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)


The first of four extra-embryonic membranes to form during EMBRYOGENESIS. In REPTILES and BIRDS, it arises from endoderm and mesoderm to incorporate the EGG YOLK into the DIGESTIVE TRACT for nourishing the embryo. In placental MAMMALS, its nutritional function is vestigial; however, it is the source of INTESTINAL MUCOSA; BLOOD CELLS; and GERM CELLS. It is sometimes called the vitelline sac, which should not be confused with the VITELLINE MEMBRANE of the egg.


Organic esters of thioglycolic acid (HS-CH2COOH).


Free Tissue Transfer Flaps
Free Flaps
Free Tissue Flaps
Microsurgical Free Flaps

A mass of tissue that has been cut away from its surrounding areas to be used in TISSUE TRANSPLANTATION.


Nogo Receptor 2
NgR2 Protein
Nogo-66 Receptor-related Protein 2
Nogo Receptor-like 3 Protein
Nogo-66 Receptor Homolog 1
Reticulon 4 Receptor-like 2 Protein
RTN4RL2 Protein

A Nogo receptor that binds to MYELIN-ASSOCIATED GLYCOPROTEIN. It localizes to the GROWTH CONES of neurons in the THALAMUS; CORTEX: AMYGDALA; OLFACTORY BULBS; and HYPOTHALAMUS.


Jagged Proteins
Serrate Proteins
Serrate-Jagged Proteins
Serrate Protein

Cell surface proteins that consist of multiple extracellular EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats), including calcium-binding EGF repeats. They function as transmembrane ligands for NOTCH RECEPTORS to control CELL DIFFERENTIATION during development.


Electron Energy-Loss Spectroscopy
Spectroscopy, Electron Energy-Loss

A technique for analysis of the chemical composition of molecules. A substance is bombarded with monochromatic ELECTRONS. Some of the electrons passing through the specimen will lose energy when they ionize inner shell electrons of the atoms in the specimen. The energy loss is element dependent. Analysis of the energy loss spectrum reveals the elemental composition of a specimen. ENERGY-FILTERED TRANSMISSION ELECTRON MICROSCOPY is a type of electron energy loss spectroscopy carried out in electron microscopes specially outfitted to analyze the spectrum of electron energy loss.


A product from the iodination of tyrosine. In the biosynthesis of thyroid hormones (THYROXINE and TRIIODOTHYRONINE), tyrosine is first iodized to monoiodotyrosine.


Vastus Intermedius
Quadriceps Muscle
Vastus Medialis
Rectus Femoris
Vastus Lateralis
Quadriceps Femoris

The quadriceps femoris. A collective name of the four-headed skeletal muscle of the thigh, comprised of the rectus femoris, vastus intermedius, vastus lateralis, and vastus medialis.


Sadophos Karbofos Prioderm Carbafos Cythion Malathion Carbofos Carbophos

A wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes.


Chondromalacia Patellae
Patella, Chondromalacia Of

A degeneration of the ARTICULAR CARTILAGE of the PATELLA, caused by a decrease in sulfated MUCOPOLYSACCHARIDES in the ground substance. When accompanied by pain, it is sometimes considered part of or confused with PATELLOFEMORAL PAIN SYNDROME.


Surgical Procedures, Urologic, Male
Surgical Procedure, Urological, Male
Male Urological Surgical Procedure
Male Urological Surgical Procedures
Surgical Procedure, Urologic, Male
Procedure, Urological Surgical, Male
Male Urologic Surgical Procedure
Surgical Procedures, Urological, Male
Procedures, Urologic Surgical, Male
Urological Surgical Procedures, Male
Urological Surgical Procedure, Male
Surgery, Male Urologic
Procedures, Urological Surgical, Male
Urologic Surgical Procedure, Male
Male Urologic Surgical Procedures
Procedure, Urologic Surgical, Male
Urologic Surgical Procedures, Male
Urological Surgery, Male
Urologic Surgery, Male
Male Urologic Surgery

Surgery performed on the male genitalia.


Chymase
Chymotrypsin-Like Protease
Chymases
Chymotrypsin-Like Proteases
Chymase-1

A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.


Investigator-Subject Relationship
Investigator-Subject Relations
Researcher-Subject Relations
Researcher Subject Relationship

Interaction between research personnel and research subjects.


INK4C Protein
CDKN2C Protein
CDK6-Associated Protein p18
Cyclin-Dependent Kinase Inhibitor p18
p18INK4c Protein
Cyclin-Dependent Kinase Inhibitor 2C
p18 CDK6 Inhibitor

An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN-LIKE REPEATS. Aberrant expression of this protein has been associated with deregulated EPITHELIAL CELL growth, organ enlargement, and a variety of NEOPLASMS.


Dietary practice of avoiding animal products in any form.


Whole-Body Irradiation
Irradiation, Whole-Body
Radiation, Whole-Body
Whole-Body Radiation
Total Body Irradiation
Irradiation, Total Body

Irradiation of the whole body with ionizing or non-ionizing radiation. It is applicable to humans or animals but not to microorganisms.


A mitosporic Oxygenales fungal genus causing various diseases of the skin and hair. The species Microsporum canis produces TINEA CAPITIS and tinea corporis, which usually are acquired from domestic cats and dogs. Teleomorphs includes Arthroderma (Nannizzia). (Alexopoulos et al., Introductory Mycology, 4th edition, p305)


A genus of parasitic nematode worms which infest the duodenum and stomach of domestic and wild herbivores, which ingest it with the grasses (POACEAE) they eat. Infestation of man is accidental.


A monophyletic group of green plants that includes all land plants (EMBRYOPHYTA) and all green algae (CHLOROPHYTA and STREPTOPHYTA).


Immunoglobulins, Fab
Immunoglobulin Fab Fragments
Fab Immunoglobulin Fragments
Immunoglobulin Fab Fragment
Immunoglobulins, Fab Fragment
Ig Fab Fragments
Fab Fragments

Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.


Anticipation, Genetic
Genetic Anticipation

The apparent tendency of certain diseases to appear at earlier AGE OF ONSET and with increasing severity in successive generations. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)


Hybrid Proteins, Mutant
Chimeric Proteins, Mutant
Mutant Chimeric Proteins
Mutant Hybrid Proteins

Proteins produced from GENES that have mutated by the fusing of protein coding regions of more than one gene. Such hybrid proteins are responsible for some instances of ANTIBIOTIC RESISTANCE and defective biological processes such as NEOPLASMS.


Program Appropriateness
Program Evaluation
Program Effectiveness
Family Planning Program Evaluation
Program Sustainability
Evaluation, Program

Studies designed to assess the efficacy of programs. They may include the evaluation of cost-effectiveness, the extent to which objectives are met, or impact.


ATP Binding Cassette Transporter, Subfamily G

ATP Binding Cassette Transporter, Sub-Family G

A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters.


An antiprotozoal agent used to combat coccidial infections of swine, cattle, fowl, and other veterinary animals. Also used in controlling outbreaks of fowl typhoid and fowl cholera and in treatment of infectious enteritis.


Oligodendrocyte Transcription Factor 2
OLIG2 Protein
OLIG-2 Protein

A basic helix-loop-helix transcription factor that is required for differentiation of OLIGODENDROCYTES and motor neurons in the spinal cord, and development of somatic motor neurons in the hindbrain.


Services Insurance, Physician
Insurance, Physician Services
Physician Services, Insurance

Insurance providing benefits for the costs of care by a physician which can be comprehensive or limited to surgical expenses or for care provided only in the hospital. It is frequently called "regular medical expense" or "surgical expense".


Macromolecular Substances
Macromolecular Compounds
Macromolecular Complexes
Macromolecular Compounds and Complexes

Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.


MET Proto-Oncogene, Receptor Tyrosine Kinase

Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.


Overall and Gorham Brief Psychiatric Rating Scale

Overall-Gorham Brief Psychiatric Rating Scale

A scale comprising 18 symptom constructs chosen to represent relatively independent dimensions of manifest psychopathology. The initial intended use was to provide more efficient assessment of treatment response in clinical psychopharmacology research; however, the scale was readily adapted to other uses. (From Hersen, M. and Bellack, A.S., Dictionary of Behavioral Assessment Techniques, p. 87)


Pentam
NebuPent
Pentamidine Mesylate
Lomidine
Pentamidine
Pentacarinat
Diamidine
Pentamidin
Pentamidine Isethionate

Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.


Fatty Acid Synthetases
Fatty Acid Synthases

Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives.


Behavioral or attitudinal compliance with recognized social patterns or standards.


Retinoblastoma Like Protein p130
Retinoblastoma-Like Protein p130
Retinoblastoma-Like Protein 2
RBL2 Protein

A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.


Src Homology 2 Domain-Containing, Transforming Protein 2

SHC2 (Src Homology 2 Domain-Containing) Protein

Src Homology 2 Domain-Containing-Transforming Protein C2

SHC (Src Homology 2 Domain-Containing) Transforming Protein 2

An SHC-signaling adaptor protein that links GROWTH FACTOR RECEPTORS to SIGNAL TRANSDUCTION PATHWAYS in neurons.


Ventricular Dysfunction, Right
Right Ventricular Dysfunction

A condition in which the RIGHT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE or MYOCARDIAL INFARCTION, and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the right ventricular wall.


Gram Negative Aerobic Bacteria
Gram-Negative Aerobic Bacteria
Achromatium
Achromatiaceae
Achromobacteriaceae

A large group of aerobic bacteria which show up as pink (negative) when treated by the gram-staining method. This is because the cell walls of gram-negative bacteria are low in peptidoglycan and thus have low affinity for violet stain and high affinity for the pink dye safranine.


Trypsin Inhibitor, alpha 1-Antitrypsin
alpha 1-Antitrypsin
alpha 1-Protease Inhibitor
alpha 1-Antiproteinase
Serpin A1
A1PI
alpha 1-Proteinase Inhibitor
alpha 1 Antiprotease
Prolastin
Zemaira

Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL ELASTASE; and other PROTEOLYTIC ENZYMES.


Rods of bone, metal, or other material used for fixation of the fragments or ends of fractured bones.


Myosin Type IV
Myosin IV
High Molecular Weight Myosin I
HMWMI

A subclass of myosin found in ACANTHAMOEBA. It is a non-filamentous myosin containing a single 180-kDa myosin heavy chain.


Agarose
Sepharose C1 4B
Sepharose
Sepharose 4B


A plant genus of the family Alstroemeriaceae. Members contain allergens, tuliposide A and tulipalin A.


General or unspecified injuries involving the fingers.


Calorimetric Differential Thermal Analysis

Differential Thermal Analysis, Calorimetric

Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.


Cranial Fossa, Anterior
Anterior Cranial Fossa
Olfactory Groove

The compartment containing the inferior part and anterior extremities of the frontal lobes (FRONTAL LOBE) of the cerebral hemispheres. It is formed mainly by orbital parts of the FRONTAL BONE and the lesser wings of the SPHENOID BONE.


Bacterial Proton-Translocating ATPases
Bacterial F(1)F(0) ATPases

Membrane-bound proton-translocating ATPases that serve two important physiological functions in bacteria. One function is to generate ADENOSINE TRIPHOSPHATE by utilizing the energy provided by an electrochemical gradient of protons across the cellular membrane. A second function is to counteract a loss of the transmembrane ion gradient by pumping protons at the expense of adenosine triphosphate hydrolysis.


Bronchial Alveolar Lavage Fluid
Bronchoalveolar Lavage Fluid
Lung Lavage Fluid
Lavage Fluid, Bronchial
Bronchial Lavage Fluid
Pulmonary Lavage Fluid
Lavage Fluid, Lung
Alveolar Lavage Fluid

Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung.


ADF Protein (Actin Depolymerizing Factor)

A member of the actin depolymerizing factors. Its depolymerizing activity is independent of HYDROGEN-ION CONCENTRATION.


Pulsed Radio Frequency Treatment
Pulsed Radiofrequency Treatment

The application, often via IMPLANTED ELECTRODES, of short bursts of electrical energy in the radiofrequency range, interspersed with pauses in delivery of the current long enough to dissipate the generated heat and avoid heat-induced tissue necrosis.


The type species of PARVOVIRUS prevalent in mouse colonies and found as a contaminant of many transplanted tumors or leukemias.


Replication Origin
ori Region
Origin of Replication

A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)


Veterinary Technicians
Nurses, Veterinary
Animal Care Technicians
Assistants, Veterinary
Animal Care Assistants
Veterinary Nurses
Animal Technicians
Technicians, Veterinary
Veterinary Assistants
Laboratory Animal Technologists

Assistants to a veterinarian, biological or biomedical researcher, or other scientist who are engaged in the care and management of animals, and who are trained in basic principles of animal life processes and routine laboratory and animal health care procedures. (Facts on File Dictionary of Health Care Management, 1988)


White Coat Hypertension
Isolated Clinic Hypertension
White Coat Syndrome

Phenomenon where BLOOD PRESSURE readings are elevated only when taken in clinical settings.


Muscle Cells
Myocytes
Muscle Cells, Mature

Mature contractile cells, commonly known as myocytes, that form one of three kinds of muscle. The three types of muscle cells are skeletal (MUSCLE FIBERS, SKELETAL), cardiac (MYOCYTES, CARDIAC), and smooth (MYOCYTES, SMOOTH MUSCLE). They are derived from embryonic (precursor) muscle cells called MYOBLASTS.


Aziridines
Azacyclopropanes, Saturated
Ethyleneimines
Dimethyleneimines

Saturated azacyclopropane compounds. They include compounds with substitutions on CARBON or NITROGEN atoms.


Pregnenolone Carbonitrile, (3 beta,16 beta)-Isomer

Pregnenolone Carbonitrile, (3 beta)-Isomer

A catatoxic steroid and microsomal enzyme inducer having significant effects on the induction of cytochrome P450. It has also demonstrated the potential for protective capability against acetaminophen-induced liver damage.


Cystic Kidney Diseases
Kidney Diseases, Cystic
Kidney, Cystic
Cystic Renal Diseases


Phakomatoses
Phakomatosis
Phacomatosis
Phacomatoses
Neurocutaneous Syndromes
Neurocutaneous Disorders
Neuroectodermal Dysplasia Syndromes

A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs.


Chemotactic Factor, Neutrophil, Monocyte-Derived

Monocyte-Derived Neutrophil Chemotactic Factor

Alveolar Macrophage Chemotactic Factor-I

A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.


N-Methyl-D-aspartic Acid
N-Methyl-D-aspartate
N-Methylaspartate
NMDA

An amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors (RECEPTORS, NMDA).


Mefenaminic Acid
Mefacit
Pinalgesic
Dysman
Mefac
Ponstan
Ponalar
Ponstan Forte
Coslan
Ponmel
Ponsyl
Pontal
Contraflam
Mefenamic Acid
Nu-Mefenamic
Ponalgic
Ponstel
Apo-Mefenamic
Mefic
Parkemed
PMS-Mefenamic Acid

A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.


Heart Valve Prosthesis
Cardiac Valve Prosthesis
Prosthesis, Heart Valve

A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.


Chromatography, High Performance Liquid
Chromatography, Liquid, High Pressure
Chromatography, High Pressure Liquid
Chromatography, High Speed Liquid
HPLC

Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.


Organic esters or salts of sulfonic acid derivatives containing an aliphatic hydrocarbon radical.


Quincke's Edema
Urticaria, Giant
Angioedema
Angioneurotic Edema

Swelling involving the deep DERMIS, subcutaneous, or submucosal tissues, representing localized EDEMA. Angioedema often occurs in the face, lips, tongue, and larynx.


Surgical Sponges
Sponges, Surgical
Surgical Sponge
Sponge, Surgical

Gauze material used to absorb body fluids during surgery. Referred to as GOSSYPIBOMA if accidentally retained in the body following surgery.


Acetonitriles
Cyanomethanes
Methyl Cyanides
Ethane Nitriles

Compounds in which a methyl group is attached to the cyano moiety.


Mangabey, Sooty
Sooty Mangabey
Cercocebus atys

A species of Old World monkeys from the genera CERCOCEBUS that is important in AIDS research. They may be naturally or experimentally infected with the SIMIAN IMMUNODEFICIENCY VIRUS. They inhabit African forests from Sierra Leone to the Congo Republic.


HLA-DRB1 Antigen
HLA-DRB1
HLA DRB1
HLA-DRB1 Chains

A subtype of HLA-DRB beta chains that includes over one hundred allele variants. The HLA-DRB1 subtype is associated with several of the HLA-DR SEROLOGICAL SUBTYPES.


Achaete-Scute Complex Genome Region
Achaete-Scute Gene Complex

A genomic region found in DROSOPHILA. The region contains genes encoding BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS that play a critical role in the regulation of pattern formation during EMBRYONIC DEVELOPMENT.


Fees
Fees and Charges
Charges and Fees
Charges

Amounts charged to the patient as payer for health care services.


Multilocus Sequence Typing
Multilocus Sequence Analysis

Direct nucleotide sequencing of gene fragments from multiple housekeeping genes for the purpose of phylogenetic analysis, organism identification, and typing of species, strain, serovar, or other distinguishable phylogenetic level.


Benzyloxyresorufin O-Dealkylase
CYP 2B1
Cytochrome P-450 CYP2B1
Pentoxyresorufin O-Dealkylase
CYP2B1
PROD
Cytochrome P450 2B1
BROD
7-Benzyloxyresorufin O-Dealkylase
7-Pentylresorufin O-Depentylase

A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.


A PYRIDOXAL PHOSPHATE-containing enzyme that catalyzes the transfer of a formyl group from L-GLUTAMATE to N-formimidoyl-L-glutamate and TETRAHYDROFOLATE. This enzyme may also catalyze formyl transfer from 5-formyltetrahydrofolate to L-GLUTAMATE. This enzyme was formerly categorized as EC 2.1.2.6.


Vascular Diseases, Spinal Cord
Spinal Cord Vascular Diseases
Hematomyelia
Posterior Spinal Artery Syndrome

Pathological processes involving any of the BLOOD VESSELS feeding the SPINAL CORD, such as the anterior and paired posterior spinal arteries or their many branches. Disease processes may include ATHEROSCLEROSIS; EMBOLISM; and ARTERIOVENOUS MALFORMATIONS leading to ISCHEMIA or HEMORRHAGE into the spinal cord (hematomyelia).


Receptors, Interleukin-4, 13
Receptor, Interleukin-4, 13
Interleukin-4 Receptor Type II
Interleukin-4, 13 Receptor
Receptors, Interleukin-4, Type II
Type II Interleukin-4 Receptor
Interleukin-4 Receptors, Type II
IL-4 Receptors, Type II
Type II Interleukin-4 Receptors
Interleukin-4, 13 Shared Receptor

An interleukin receptor subtype found on both hematopoietic and non-hematopoietic cells. It is a membrane-bound heterodimer that contains the INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT and the INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT. Although commonly referred to as the interleukin-4 type-II receptor this receptor has specificity for both INTERLEUKIN-4 and INTERLEUKIN-13


In Vitro as Topic
In Vitro
In Vitro Techniques


Calcitonin Gene-Related Peptide Receptor Antagonists

Pharmacologic agents that block NOCICEPTIVE PAIN signaling from CALCITONIN GENE-RELATED PEPTIDE RECEPTORS. They may be useful for the treatment of pain associated with MIGRAINE DISORDERS and OSTEOARTHRITIS.


The species Megaptera novaeangliae, in the family Balaenopteridae, characterized by its huge flippers and the arching of their back when diving. They are also known for their breaching and singing.


A type of ALPHAPAPILLOMAVIRUS associated with high risk for anogenital neoplasms.


Union Catalog as Topic
Catalogs, Union as Topic

Works about lists of books and other information sources held among a cooperating group of LIBRARIES.


Sulfites
Sulfites, Inorganic
Inorganic Sulfites


Kalonji
Black Cumin
Nigella sativa
Cumin, Black

A plant genus of the family RANUNCULACEAE that contains alpha-hederin, a triterpene saponin in the seeds, and is the source of black seed oil.


A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in membranes and is used as a tool in cellular biochemistry, and reagent for precipitating cholesterol. It has no cardiac effects.


Matrix Attachment Region Binding Proteins

Proteins that bind to the MATRIX ATTACHMENT REGIONS of DNA.


An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.


Prostaglandin Inhibitor
Inhibitors, Prostaglandin
Prostaglandin Inhibitors
Prostaglandin Antagonists
Antagonists, Prostaglandin
Prostaglandin Antagonist

Compounds that inhibit the action of prostaglandins.


Ultrasound, High-Intensity Focused, Transrectal

Transrectal High-Intensity Focused Ultrasound

Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).


Videorecording
Video Recording
Audiovisual Recording

The storing or preserving of video signals to be played back later via a transmitter or receiver.


Disintegrin and Metalloproteinase Domain-Containing Protein 12

A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12-L) and a short soluble form  (ADAM12-S). It modulates the cleavage of INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS and may also regulate CELL FUSION during MYOGENESIS.


Adjuvants, Immunological
Adjuvant, Immunologic
Immunoactivators
Immunostimulants
Immunoadjuvants
Immunologic Adjuvants
Adjuvants, Immunologic
Immunological Adjuvant
Immunopotentiators

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.


Radioisotope Dilution Technic
Radioisotope Dilution Technique

Method for assessing flow through a system by injection of a known quantity of radionuclide into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)


Travel Documents
Records as Topic
Records
Personal Identification Systems

Works on authentic evidence, of something having legal importance. The concept includes certificates of birth, death, etc., as well as hospital, medical, and other institutional records.


Glucochloral beta-Chloralose Anhydroglucochloral alpha-Chloralose Chloralose Glucochloralose

A derivative of CHLORAL HYDRATE that was used as a sedative but has been replaced by safer and more effective drugs. Its most common use is as a general anesthetic in animal experiments.


Preventive Surgical Procedures
Surgical Procedures, Prophylactic
Surgical Procedures, Preventive
Prophylactic Surgical Procedures

Surgical procedures done to prevent or reduce the risk of developing cancer or other disease conditions in persons who may be predisposed to such conditions.


Membrana Synovialis Capsulae Articularis

The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.


HLA-DRB4
HLA DRB4
HLA-DRB4 Antigen
HLA-DRB4 Chains

A subtype of HLA-DRB beta chains that is associated with the HLA-DR53 serological subtype.


Prenatal Nutritional Physiological Phenomenon

Prenatal Nutritional Physiological Phenomena


Vertebrogenic Pain Syndrome
Back Pain with Radiation
Back Ache
Back Pain without Radiation
Back Pain
Backache

Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.


Optoacoustic Techniques
Photoacoustic Techniques
Photoacoustic Technologies
Optoacoustic Technologies

Investigative and diagnostic methods and procedures based on the photoacoustic effect, which is the generation of SOUND WAVES from the absorption of ELECTROMAGNETIC RADIATION.


P22 Phage
Phage P22
Enterobacteria phage P22
Bacteriophage P22

A species of temperate bacteriophage in the genus P22-like viruses, family PODOVIRIDAE, that infects SALMONELLA species. The genome consists of double-stranded DNA, terminally redundant, and circularly permuted.


Inherited Amino Acid Transport Disorders

Disorders characterized by defective transport of amino acids across cell membranes. These include deficits in transport across brush-border epithelial cell membranes of the small intestine (MICROVILLI) and KIDNEY TUBULES; transport across the basolateral membrane; and transport across the membranes of intracellular organelles. (From Nippon Rinsho 1992 Jul;50(7):1587-92)


Erythromycin Propionate Monododecyl Sulfate

A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.


Twinning, Embryo
Embryo Twinning
Embryonic Twinning
Twinning, Embryonic

The development of two EMBRYOS in a single UTERUS at the same time.


Testing or screening required by federal, state, or local law or other agencies for the diagnosis of specified conditions. It is usually limited to specific populations such as categories of health care providers, members of the military, and prisoners or to specific situations such as premarital examinations or donor screening.


Infections, Birnaviridae
Birnaviridae Infections

Virus diseases caused by the BIRNAVIRIDAE.


Mitogen Activated Protein Kinase p49(3F12)

A c-jun amino-terminal kinase that is found predominantly within NEURONS of the BRAIN, suggesting a role in stress-induced neuronal APOPTOSIS. Several isoforms of the protein with molecular sizes of 47 kDa and 52 kDa exist due to multiple ALTERNATIVE SPLICING.


AC133 Antigen
Prominin-1
AC133-1 Antigen
Fudenine
AC141 Antigen
Prominin
PROML1
Prominin-Like PROML1
AC133-2 Antigen
CD133 Antigen

A member of the prominin family, AC133 Antigen is a 5-transmembrane antigen occurring as several isoforms produced by alternative splicing which are processed into mature forms. In humans, it is expressed as a subset of CD34 (bright) human hematopoietic stem cells and CD34 positive leukemias. Functionally, it is associated with roles in cell differentiation, proliferation, and apoptosis. Specifically, it regulates the organization of apical plasma membrane in epithelial cells, disk morphogenesis during early retinal development, MAPK and Akt signaling pathways, and in cholesterol metabolism.


Scanning Electrochemical Microscopy
Electrochemical Scanning Microscopy
Microscopy, Electrochemical, Scanning

A scanning probe microscopy technique that uses an ultramicroelectrode as the scanning probe that simultaneously records changes in electrochemical potential as it scans thereby creating topographical images with localized electrochemical information.


A synthetic precursor of norepinephrine that is used in the treatment of PARKINSONIAN DISORDERS and ORTHOSTATIC HYPOTENSION.


Anisocoria, Physiologic
Pupillary Size Inequality
Pupil Diameter Unequal
Anisocoria

Unequal pupil size, which may represent a benign physiologic variant or a manifestation of disease. Pathologic anisocoria reflects an abnormality in the musculature of the iris (IRIS DISEASES) or in the parasympathetic or sympathetic pathways that innervate the pupil. Physiologic anisocoria refers to an asymmetry of pupil diameter, usually less than 2mm, that is not associated with disease.


Type IIb Sodium-Phosphate Cotransporter Proteins

Type IIb Sodium-Phosphate Symporter Proteins

Sodium-Phosphate Cotransporter Proteins, Type IIb

A sodium-dependent phosphate transporter present primarily at apical sites of EPITHELIAL CELLS in the SMALL INTESTINE.


Antagonists, Serotonin
Serotonin Receptor Blockers
Serotonin Receptor Antagonists
Serotonin Blockaders
Antiserotonergic Agents
Serotonin Antagonists
5-Hydroxytryptamine Antagonists
Antagonists, 5-Hydroxytryptamine
Antagonists, 5-HT
5-HT Antagonists

Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS.


RNA, Transfer, Methyltransferases
RNA Methylases
T RNA Methyltransferases
tRNA Methyltransferases

Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases within a transfer RNA molecule. EC 2.1.1.


Complications of Diabetes Mellitus
Diabetic Complications
Diabetes-Related Complications
Diabetes Complications

Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.


Fifth-Nerve Palsy, Traumatic
Fifth-Nerve Trauma
Trigeminal Nerve Contusion
Cranial Nerve V Injury
Trigeminal Nerve Trauma
Fifth Cranial Nerve Injuries
Trigeminal Nerve Injury
Trigeminal Nerve Injuries
Traumatic Fifth-Nerve Palsy
Fifth Cranial Nerve Injury
Trigeminal Nerve Transection
Trigeminal Neuropathy, Traumatic
Injury, Fifth Cranial Nerve
Injury, Cranial Nerve V
Trigeminal Nerve Avulsion

Traumatic injuries to the TRIGEMINAL NERVE. It may result in extreme pain, abnormal sensation in the areas the nerve innervates on face, jaw, gums and tongue and can cause difficulties with speech and chewing. It is sometimes associated with various dental treatments.


The aggregate enterprise of manufacturing and technically producing books. (From Random House Unabridged Dictionary, 2d ed)


Antiprotozoal and antimicrobial agent used mainly in veterinary practice.


Submucous Plexus
Meissner's Plexus
Submucosal Plexus

One of two ganglionated neural networks which together form the enteric nervous system. The submucous (Meissner's) plexus is in the connective tissue of the submucosa. Its neurons innervate the epithelium, blood vessels, endocrine cells, other submucosal ganglia, and myenteric ganglia, and play an important role in regulating ion and water transport. (From FASEB J 1989;3:127-38)


A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.


Ig Subunits
Ig Polypeptide Chains
Ig Subunit
Immunoglobulin Subunits
Immunoglobulin Chains
Immunoglobulin Polypeptide Chains

The PROTEIN SUBUNITS of the multimeric IMMUNOGLOBULIN proteins, such as IGA; IGD; IGE; IGG; and IGM. Included are the heavy and light chains which contain the specific ANTIGEN binding domains, as well as the accessory proteins that are part of the the secreted forms of IGM and IGA; (SECRETORY IGA).


Guanylyl Cyclase C
Heat-Stable Enterotoxin Receptors
Enterotoxin-Guanylin Receptor
Enterotoxin-Guanylin Receptors
GC-C Receptors
Receptor, Enterotoxin
Guanylin-Uroguanylin Receptors
GC-C Receptor
Receptor, Guanyl Cyclase-C
Guanyl Cyclase-C Receptor
Heat-Stable Enterotoxin Receptor
Enterotoxin Receptor
Receptors, Guanyl Cyclase-C
Receptors, Enterotoxin
Guanyl Cyclase-C Receptors
Enterotoxin Receptors
Guanylin-Uroguanylin Receptor

Guanylate cyclase-coupled receptors that bind bacterial ENTEROTOXINS, as well as the endogenous peptides guanylin and uroguanylin. Ligand binding stimulates production of CYCLIC GMP by EPITHELIAL CELLS of the intestinal lumen, altering barrier permeability and mucus secretion. Mutations in the gene (GUCY2C) encoding this receptor are associated with some cases of hereditary diarrhea (Diarrhea 6) and MECONIUM ILEUS.


Mixed Leukocyte Reaction
Mixed Leukocyte Culture Test
Mixed Lymphocyte Culture Test
Leukocyte Culture Test, Mixed
Lymphocyte Culture Test, Mixed
Mixed Lymphocyte Reaction

Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.


Polyoxyethylene Polyoxypropylene Polyoxyethylene Polymer

A copolymer of polyethylene and polypropylene ether glycol. It is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.


An oil from flower buds of SYZYGIUM trees which contains large amounts of EUGENOL.


Resin-Bonded Acid-Etched Fixed Partial Denture

A commonly used prosthesis that results in a strong, permanent restoration. It consists of an electrolytically etched cast-metal retainer that is cemented (bonded), using resins, to adjacent teeth whose enamel was previously acid-treated (acid-etched). This type of bridgework is sometimes referred to as a Maryland bridge.


A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS.  Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE.


Rod Outer Segments
Rod Outer Segment
Rod Cell Outer Segment

The portion of a retinal rod cell situated between the ROD INNER SEGMENT and the RETINAL PIGMENT EPITHELIUM. It contains a stack of photosensitive disk membranes laden with RHODOPSIN.


Follicular Thyroid Carcinoma
Thyroid Carcinoma, Follicular
Adenocarcinoma, Follicular

An adenocarcinoma of the thyroid gland, in which the cells are arranged in the form of follicles. (From Dorland, 27th ed)


ATP Binding Cassette Transporter, Sub-Family G, Member 1

ATP Binding Cassette Transporter, Subfamily G, Member 1

ATP binding cassette transporter that functions primarily as a lipid and CHOLESTEROL exporter in MACROPHAGES.  It may also function in intracellular lipid transport and homoeostasis.


Fetal Cell Research
Fetal Tissue Research
Fetal Experimentation
Fetal Research

Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus in the postembryonic period, after the major structures have been outlined. In humans, this corresponds to the period from the third month after fertilization until birth.


Branched DNA Assay
bDNA Assay
bDNA Signal Amplification Assay
Branched DNA Signal Amplification Assay

A molecular probe technique that utilizes branched DNA (bDNA) as a means to amplify the hybridization signal. One end of the bDNA molecule is designed to bind a specific target, while the other end of the bDNA molecule contains many branches of DNA that are designed to bind a probe used for signal detection.


NF-D Nuclear Factor
Nuclear Matrix Protein 1
Yin-Yang-1 Protein
Delta Transcription Factor
YY1 Transcription Factor
Transcriptional Repressor Protein YY1

A ubiquitously expressed zinc finger-containing protein that acts both as a repressor and activator of transcription. It interacts with key regulatory proteins such as TATA-BINDING PROTEIN; TFIIB; and ADENOVIRUS E1A PROTEINS.


Balantidiasis
B. coli Infection
Balantidium Infection
Balantidium coli Infection

Infection by parasites of the genus BALANTIDIUM. The presence of Balantidium in the LARGE INTESTINE leads to DIARRHEA; DYSENTERY; and occasionally ULCER.


Cadmium Dichloride
Cadmium Chloride
CdCl2

A cadmium halide in the form of colorless crystals, soluble in water, methanol, and ethanol. It is used in photography, in dyeing, and calico printing, and as a solution to precipitate sulfides. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)


Occluding Junctions
Tight Junctions
Zonula Occludens

Cell-cell junctions that seal adjacent epithelial cells together, preventing the passage of most dissolved molecules from one side of the epithelial sheet to the other. (Alberts et al., Molecular Biology of the Cell, 2nd ed, p22)


An order of gram-positive bacteria in the class Bacilli, that have the ability to ferment sugars to lactic acid. They are widespread in nature and commonly used to produce FERMENTED FOODS AND BEVERAGES.


Isotype Switching
Immunoglobulin Class Switching
Ig Class Switching
Class Switching

Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.


15-Methylprostaglandin F2alpha
15(S)-15-Methyl PGF2alpha
Carboprost

A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of PREGNANCY.


Wrongful Life
Wrongful Lives
Wrongful Birth

In civil law a cause of action which alleges that a defendant has wrongfully caused a child to be born.


Lipids containing at least one monosaccharide residue and either a sphingoid or a ceramide (CERAMIDES). They are subdivided into NEUTRAL GLYCOSPHINGOLIPIDS comprising monoglycosyl- and oligoglycosylsphingoids and monoglycosyl- and oligoglycosylceramides; and ACIDIC GLYCOSPHINGOLIPIDS which comprises sialosylglycosylsphingolipids (GANGLIOSIDES); SULFOGLYCOSPHINGOLIPIDS (formerly known as sulfatides), glycuronoglycosphingolipids, and phospho- and phosphonoglycosphingolipids. (From IUPAC's webpage)


GNB2L1 Protein
Receptor of Activated C Kinase 1
Protein Kinase C Receptors
GNB2-RS1 Protein
RACK1 Protein
Receptors for Activated C Kinase
Receptor for Activated C Kinase
Protein Kinase C Receptor
Receptor, Protein Kinase C

Receptors for PROTEIN KINASE C that consist of seven WD40 REPEATS. They function in a wide variety of cellular and physiologic processes including the assembly of signaling complexes, protein translation, cell growth and proliferation, APOPTOSIS, and MUSCARINIC RECEPTOR transport. RACK1 depends on protein kinase C activity to translocate from the perinuclear region to the cell periphery and associates with the plasma membrane through interactions with KERATIN-1 and INTEGRIN BETA-1.


CBL E3 Ubiquitin Protein Ligase
Proto-Oncogene Proteins c-cbl
c-cbl Protein
c-cbl Proto-Oncogene Protein
RNF55 Protein
Proto-Oncogene Protein c-cbl
cbl Proto-Oncogene Protein
RING Finger Protein 55

Proto-oncogene proteins that negatively regulate RECEPTOR PROTEIN-TYROSINE KINASE signaling. It is a UBIQUITIN-PROTEIN LIGASE and the cellular homologue of ONCOGENE PROTEIN V-CBL.


Polymerized forms of styrene used as a biocompatible material, especially in dentistry. They are thermoplastic and are used as insulators, for injection molding and casting, as sheets, plates, rods, rigid forms and beads.


Carboxylic acids that contain a KETONE group.


Receptor-Interacting Serine-Threonine Kinase 2

Receptor-Interacting Protein Serine-Threonine Kinase 2

CARD-containing Interleukin (IL)-1 beta Converting Enzyme

A RIP serine-theonine kinase that contains a C-terminal caspase activation and recruitment domain. It can signal by associating with other CARD-signaling adaptor proteins and INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.


Complement Receptors
Complement Receptor Type 1
Receptors, Complement
Complement Receptor

Molecules on the surface of some B-lymphocytes and macrophages, that recognize and combine with the C3b, C3d, C1q, and C4b components of complement.


Compounds that bind to and reduce the biological availability of a chemical or pharmaceutical agent.


Ruta
Ruta graveolens
Ruta chalepensis
Rue

A plant genus of the family RUTACEAE. Members contain quinoline alkaloids.


Those disorders that have a disturbance in mood as their predominant feature.


One of a pair of thick-walled tubes that transports urine from the KIDNEY PELVIS to the URINARY BLADDER.


Ambulation, Early
Accelerated Ambulation
Early Ambulation
Early Mobilization

Procedure to accelerate the ability of a patient to walk or move about by reducing the time to AMBULATION. It is characterized by a shorter period of hospitalization or recumbency than is normally practiced.


Theory, Psychological
Theories, Psychological
Psychological Theories
Psychologic Theory
Psychological Theory

Principles applied to the analysis and explanation of psychological or behavioral phenomena.


Hemorrhage, Putamen
Brain Hemorrhage, Putaminal
Putaminal Hematoma
Putaminal Hemorrhage


Dehydroisoandrosterone Sulfate
DHEA Sulfate
Prasterone Sulfate
DHA Sulfate
Dehydroepiandrosterone Sulfate

The circulating form of a major C19 steroid produced primarily by the ADRENAL CORTEX. DHEA sulfate serves as a precursor for TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE.


Leukemia, Juvenile Myelomonocytic
Juvenile Chronic Myelogenous Leukemia
Leukemia, Myelomonocytic, Juvenile
Juvenile Myelomonocytic Leukemia

A leukemia affecting young children characterized by SPLENOMEGALY, enlarged lymph nodes, rashes, and hemorrhages. Traditionally classed as a myeloproliferative disease, it is now considered a mixed myeloproliferative-mylelodysplastic disorder.


P2 Purinoceptor Agonists
Purinergic P2 Receptor Agonists

Compounds that bind to and stimulate PURINERGIC P2 RECEPTORS.


A method of lowering core BODY TEMPERATURE by filling the STOMACH with chilled fluids.


Trimester, Third
Pregnancy Trimester, Third
Pregnancy, Third Trimester
Last Trimester

The last third of a human PREGNANCY, from the beginning of the 29th through the 42nd completed week (197 to 294 days) of gestation.


Hypertension, Ocular
Glaucoma, Suspect
Ocular Hypertension

A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.


A fabricated tooth substituting for a natural tooth in a prosthesis. It is usually made of porcelain or plastic.


Dihydromorphinone
Hydromorphon
Palladone
Hydromorphone
Laudacon
Hydromorphone Hydrochloride
Dilaudid

Hydromorphone hydrochloride extended release.


Hepatic Porphyria
Porphyrias, Hepatic
Porphyria, Hepatic

A group of metabolic diseases due to deficiency of one of a number of LIVER enzymes in the biosynthetic pathway of HEME. They are characterized by the accumulation and increased excretion of PORPHYRINS or its precursors. Clinical features include neurological symptoms (PORPHYRIA, ACUTE INTERMITTENT), cutaneous lesions due to photosensitivity (PORPHYRIA CUTANEA TARDA), or both (HEREDITARY COPROPORPHYRIA). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues.


VEGF-Related Factor, VEGF-B
VEGF-Related Protein, VEGF-B
Vascular Endothelial Growth Factor-B
VEGF-B
Vascular Endothelial Growth Factor B

A vascular endothelial growth factor expressed in a variety of tissues. It binds with high specificity to VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 and NEUROPILIN-1.


Immune Receptor Tyrosine-Based Activation Motif

Immunoreceptor Tyrosine-Based Activation Motif

Immuno-Receptor Tyrosine-Based Activation Motif

A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins involved in various IMMUNE RESPONSES. The CONSENSUS SEQUENCE of this motif is YXXL(or I)X(6-8)YXXL(or I) (where X denotes any amino acid). When phosphorylated ITAM motifs provide docking sites for PROTEIN TYROSINE KINASES of the Syk family thus forming signaling complexes which lead to activation of immune responses.


Antigens, CD57
HNK-1 Antigen
CD57 Antigen
CD57 Antigens
Leu-7 Antigen

Oligosaccharide antigenic determinants found principally on NK CELLS and T-CELLS. They are expressed at high levels in terminally differentiated or senescent cells with reduced proliferative capacity; however, their role in the immune response is poorly understood.


Developmental Genes
Genes, Developmental

Genes that determine the fate of a cell or CELLS in a region of the embryo during EMBRYONIC DEVELOPMENT.


Angelicins Psoralens Furocoumarins Furanocoumarins


Parasitic Skin Diseases
Skin Diseases, Parasitic

Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites.


Calorimetry, Indirect
Calorimetry, Respiration

Calculation of the energy expenditure in the form of heat production of the whole body or individual organs based on respiratory gas exchange.


Receptors, IL-3
IL-3 Receptor
Receptors, Interleukin-3
IL3 Receptors
IL3 Receptor
Interleukin-3 Receptors
Interleukin-3 Receptor
IL-3 Receptors

High affinity receptors for INTERLEUKIN-3. They are found on early HEMATOPOIETIC PROGENITOR CELLS; progenitors of MYELOID CELLS; EOSINOPHILS; and BASOPHILS. Interleukin-3 receptors are formed by the dimerization of the INTERLEUKIN-3 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR COMMON BETA SUBUNIT.


One of two salivary glands in the neck, located in the space bound by the two bellies of the digastric muscle and the angle of the mandible. It discharges through the submandibular duct. The secretory units are predominantly serous although a few mucous alveoli, some with serous demilunes, occur. (Stedman, 25th ed)


Mucopeptide Amidohydrolase
Autolysin
Peptidoglycan Hydrolase
T7 Lysozyme
LE-Enzyme
N-Acetylmuramoyl-L-alanine Amidase
Murein Hydrolase
T7 Endolysin

An autolytic enzyme bound to the surface of bacterial cell walls. It catalyzes the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell wall glycopeptides, particularly peptidoglycan. EC 3.5.1.28.


Hemagglutinins Isohemagglutinins Exohemagglutinins Hemagglutinin

Agents that cause agglutination of red blood cells. They include antibodies, blood group antigens, lectins, autoimmune factors, bacterial, viral, or parasitic blood agglutinins, etc.


A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.


ECG Electrocardiogram Electrocardiograph EKG Electrocardiography

Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.


Cytochrome c1
Cytochrome c-1
Cytochromes c1

The 30-kDa membrane-bound c-type cytochrome protein of mitochondria that functions as an electron donor to CYTOCHROME C GROUP in the mitochondrial and bacterial RESPIRATORY CHAIN. (From Enzyme Nomenclature, 1992, p545)


RTN4R Protein
Reticulon-4 Receptor
Nogo-66 Receptor
NgR1 Protein
Nogo Receptor 1

A high affinity receptor for myelin-associated inhibitors (MAIs) that include NOGO-A PROTEIN; OLIGODENDROCYTE MYELIN GLYCOPROTEIN; and MYELIN-ASSOCIATED GLYCOPROTEIN. It is expressed primarily by neurons in the brain and OLFACTORY BULBS. During embryonic development, it is expressed in the PERIPHERAL NERVOUS SYSTEM.  It localizes to GROWTH CONES and may inhibit neurite outgrowth following SPINAL INJURY.


Non-neoplastic tumor-like lesions at joints, developed from the SYNOVIAL MEMBRANE of a joint through the JOINT CAPSULE into the periarticular tissues. They are filled with SYNOVIAL FLUID with a smooth and translucent appearance. A synovial cyst can develop from any joint, but most commonly at the back of the knee, where it is known as POPLITEAL CYST.


Glucagonoma Syndrome
Glucagonoma
Adenoma, alpha-Cell
alpha-Cell Tumor

An almost always malignant GLUCAGON-secreting tumor derived from the PANCREATIC ALPHA CELLS. It is characterized by a distinctive migratory ERYTHEMA; WEIGHT LOSS; STOMATITIS; GLOSSITIS; DIABETES MELLITUS; hypoaminoacidemia; and normochromic normocytic ANEMIA.


Dental Implantation, Endosseous, Endodontic

Insertion of a tapered rod through the root canal into the periapical osseous structure to lengthen the existing root and provide individual tooth stabilization.


Jumonji Domain-Containing Histone Demethylases

JmjC Domain-Containing Histone Demethylases

A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.


The inner zone of the adrenal cortex. This zone produces the enzymes that convert PREGNENOLONE, a 21-carbon steroid, to 19-carbon steroids (DEHYDROEPIANDROSTERONE; and ANDROSTENEDIONE) via 17-ALPHA-HYDROXYPREGNENOLONE.


ELF-1 Protein, Mammalian
Ephrin-A2
Cek7 RPTK Ligand
Eph Ligand Family 1 Protein, Mammalian
EPLG6 Gene Product
LERK-6 Protein
Cek7 Ligand

A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR-containing ephrin with a high affinity for the EPHA3 RECEPTOR. Early in embryogenesis it is expressed at high levels in the MESENCEPHALON; SOMITES; branchial arches, and LIMB BUDS.


ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B)

HuB Paraneoplastic Encephalomyelitis Antigen

A neural-specific RRM protein that binds to several 3'UTRs, including its own as well as that of PROTO-ONCOGENE PROTEINS C-FOS  and ID DNA BINDING PROTEIN INHIBITOR. It binds through the recognition of a GAAA motif in the RNAs.


Cross-Disciplinary Communication
Multidisciplinary Communication
Interdisciplinary Communication
Communication Research

An academic field that deals with processes of human communication.


An inactive stage between the larval and adult stages in the life cycle of INSECTA.


Latex Fixation Tests
Latex Agglutination Tests

Passive agglutination tests in which antigen is adsorbed onto latex particles which then clump in the presence of antibody specific for the adsorbed antigen. (From Stedman, 26th ed)


Hypertension, Malignant
Malignant Hypertension

A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.


Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).


An order of insects, restricted mostly to the tropics, containing at least eight families. A few species occur in temperate regions of North America.


Organizational Change Management
Change Management

Processes, tools, and techniques involved in the management of ORGANIZATIONAL INNOVATION, the purpose of which is to help individuals and work groups make successful personal transitions which ensure overall successful outcomes.


Plant-Derived Chemicals
Phytonutrient
Dietary Phytochemicals
Plant Biologically Active Compounds
Phytonutrients
Plant-Derived Compounds
Bioactive Coumpounds, Plant
Phytochemical
Phytochemicals
Plant Bioactive Compounds
Biologically Active Coumpounds, Plant

A broad range of biologically active compounds which occur naturally in plants having important medicinal and nutritional properties.


Drug Resistance, Multiple
Multidrug Resistance
Multi-Drug Resistance

Simultaneous resistance to several structurally and functionally distinct drugs.


A plant genus of the family BOMBACACEAE that is used for FOOD and MEDICINE, TRADITIONAL.


Smooth Muscle Myosins
Myosins, Smooth Muscle

Myosin type II isoforms found in smooth muscle.


Clathrin Assembly Protein Complex mu Subunits

A family of medium adaptin protein subunits of approximately 45 KDa in size. They have been primarily found as components of ADAPTOR PROTEIN COMPLEX 3 and ADAPTOR PROTEIN COMPLEX 4.


Educational institutions for individuals specializing in the field of library science or information.


Non-fatal immersion or submersion in water. The subject is resuscitable.


Series of ocean waves produced by geologic events or underwater LANDSLIDES. These waves can travel at speeds averaging 450 (and up to 600) miles per hour in the open ocean.


Woman's Rights
Women's Liberation
Women's Rights
Women's Status

The rights of women to equal status pertaining to social, economic, and educational opportunities afforded by society.


A potent eye, throat, and skin irritant. One of its uses is as a riot control agent.


In Vitro Maturation of Oocytes
In Vitro Oocyte Maturation
In Vitro Oocyte Maturation Techniques
Oocyte In Vitro Maturation

Methods used to induce premature oocytes, that are maintained in tissue culture, to progress through developmental stages including to a stage that is competent to undergo FERTILIZATION.


RNAi Therapeutics
RNAi-Based Therapy
RNAi Therapy
RNAi-Based Therapeutics

A form of disease treatment which involves the silencing of genes that are associated with a disease by the process of RNA INTERFERENCE.


A round-to-oval mass of lymphoid tissue embedded in the lateral wall of the PHARYNX. There is one on each side of the oropharynx in the fauces between the anterior and posterior pillars of the SOFT PALATE.


Field Training, Medical
Preceptorship
Field Work, Medical
Field Study, Medical
Clinical Practicum

Practical experience in medical and health-related services that occurs as part of an educational program wherein the professionally-trained student works outside the academic environment under the supervision of an established professional in the particular field.