2-pyridinylmethylsulfinylbenzimidazole proton pump inhibitor that is used in the treatment of GASTROESOPHAGEAL REFLUX and PEPTIC ULCER.


Loeffler Syndrome
Simple Pulmonary Eosinophilia
Eosinophilic Pneumonia
Pulmonary Eosinophilia
Pneumonia, Eosinophilic
Tropical Eosinophilic Pneumonia
Eosinophilias, Pulmonary
Pulmonary Eosinophilias
Eosinophilia, Pulmonary

Pulmonary eosinophilia or pneumonia caused by parasitic infections in tropical areas .


Physical changes in the growth patterns of a plant brought on by sustained absence of light. These changes are characterized by lengthened internodes which produce long weak stems, fewer leaves, and pale yellow color (chlorosis). The physiological basis for etiolation is induction of the phytohormone, AUXIN.


Bacterial Warfare
Warfare, Biological
Biologic Warfare
Warfare, Bacterial
Biological Warfare

Warfare involving the use of living organisms or their products as disease etiologic agents against people, animals, or plants.


P2Y1 Purinoceptor Agonists
Purinergic P2Y1 Receptor Agonists
P2Y12 Purinoceptor Agonists
Purinergic P2Y12 Receptor Agonists
Purinergic P2Y Receptor Agonists
P2Y2 Purinoceptor Agonists
P2Y Purinoceptor Agonists
Purinergic P2Y2 Receptor Agonists

Compounds that bind to and stimulate PURINERGIC P2Y RECEPTORS. Included under this heading are agonists for specific P2Y receptor subtypes.


Htk Ligand
Eph Ligand Family 2 Protein, Mammalian
Eplg5 Gene Product
LERK-5 Gene Product
Efbn2 Gene Product
Eplg5 Protein
HTKL Protein
Ephrin-B2
ELF-2 Protein, Mammalian
LERK-5 Protein
Mammalian ELF-2

A transmembrane domain containing ephrin that binds with high affinity to EPHB1 RECEPTOR; EPHB3 RECEPTOR; and EPHB4 RECEPTOR. Expression of ephrin-B2 occurs in a variety of adult tissues. During embryogenesis, high levels of ephrin-B2 is seen in the PROSENCEPHALON; RHOMBENCEPHALON; developing SOMITES; LIMB BUD; and bronchial arches.


Evaluation Studies, FDA Phase 4 as Topic

Evaluation Studies, FDA Phase IV as Topic

Works about planned post-marketing studies of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques that have been approved for general sale. These studies are often conducted to obtain additional data about the safety and efficacy of a product. This concept includes phase IV studies conducted in both the U.S. and in other countries.


Nursing Outcomes Classification Terminology

International Classification for Nursing Practice

Standardized terms used in the nursing field (e.g., NURSING INFORMATICS).


Gamadiabet Dymelor Dimelor Acetohexamide

A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide.


Polymorphic Crystals
Crystallization
Crystal Growth
Crystalline Polymorphs
Polymorphism, Crystallization

Different crystal packing configurations which result in different properties such as SOLUBILITY which affects biological activity.


Partial Monosomy
Monosomy, Partial
Chromosome Deletion


Superior Segmental Optic Nerve Hypoplasia

Underdevelopment of the superior aspect of the OPTIC NERVE HEAD.


Lecithin Cholesterol Acyltransferase Deficiency

An autosomal recessive disorder of lipoprotein metabolism caused by mutation of LECITHIN CHOLESTEROL ACYLTRANSFERASE gene. It is characterized by low HDL-cholesterol levels, and the triad of CORNEAL OPACITIES; HEMOLYTIC ANEMIA; and PROTEINURIA with renal failure.


MMP1 Metalloproteinase
Interstitial Collagenase
MMP-1 Metalloproteinase
Matrix Metalloproteinase 1
Matrix Metalloproteinase-1
proMMP-1
Pro-Matrix Metalloproteinase-1
Promatrixmetalloproteinase-1

A member of the metalloproteinase family of enzymes that is principally responsible for cleaving FIBRILLAR COLLAGEN. It can degrade interstitial collagens, types I, II and III.


Holoxan
Iso-Endoxan
Iphosphamide
NSC-109724
Isofosfamide
Isophosphamide
Ifosfamide
NSC-109,724
Asta Z 4942

Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.


Pancreatitis-Associated Proteins
Regenerating Islet-Derived Protein 3
Regenerating Islet-Derived Proteins
Pancreatitis-Associated Protein-1
Pancreatitis-Associated Protein

C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.


Panicum
Panicum virgatum
Millet, Little
Panicum miliare
Millet, Broomcorn
Panicum miliaceum
Proso Millet
Panicgrass
Switchgrass
Millet, Common

A plant genus of the family POACEAE. The seed is one of the EDIBLE GRAINS used in millet cereals and in feed for birds and livestock (ANIMAL FEED). It contains diosgenin (SAPONINS).


Bromazepam-Ratiopharm
Ro 5-3350
Lexomil
Durazanil
Bromazepam AL
Bromaz 1A Pharma
Bromazepam-Neuraxpharm
Bromazepam Beta
Apo-Bromazepam
Anxyrex
Bromazepam Heumann
Lexotan
Lexotanil
BromaLich
Bromazanil
Gen-Bromazepam
Bromazep Von Ct
Lexatin
Bromazepam

One of the BENZODIAZEPINES that is used in the treatment of ANXIETY DISORDERS.


Immunoglobulin Light Chain-Like lambda5 Peptide

lambda5 Peptide, Immunoglobulin Light Chain-Like

Surrogate Immunoglobulin kappa Light Chain

An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and an IMMUNOGLOBULIN CONSTANT REGION-like peptide (such as Vpreb1 peptide). Surrogate light chains associate with MU IMMUNOGLOBULIN HEAVY CHAINS in place of a conventional immunoglobulin light chains to form pre-B cell receptors.


Skull Fracture, Basilar
Battle's Sign
Skull Fracture, Frontobasilar
Basilar Skull Fracture
Skull Fracture, Basilar, Childhood
Skull Fracture, Transphenoid Basilar
Battle Sign

Fractures which extend through the base of the SKULL, usually involving the PETROUS BONE. Battle's sign (characterized by skin discoloration due to extravasation of blood into the subcutaneous tissue behind the ear and over the mastoid process), CRANIAL NEUROPATHIES, TRAUMATIC; CAROTID-CAVERNOUS SINUS FISTULA; and CEREBROSPINAL FLUID OTORRHEA are relatively frequent sequelae of this condition. (Adams et al., Principles of Neurology, 6th ed, p876)


Gastrocoele
Blastopore
Archenteron
Gastrula
Primitive Gut

The opening of the archenteron, central cavity of gastrula, which is formed by invagination of the BLASTULA or BLASTOCYST. Archenteron gives rise to the alimentary canal of the DIGESTIVE SYSTEM.


Argemone mexicana
Prickly Poppy
Argemone
Poppy, Prickly

A plant genus of the family PAPAVERACEAE that contains isoquinoline alkaloids.


Xantalgin
Calcium Alginate
poly(Mannuronic Acid), Sodium Salt
Alginate
Alloid G
Sodium Alginate
Alginates
Sodium Calcium Alginate
Alginic Acid, Sodium Salt
Potassium Alginate
Alginic Acid, Calcium Salt
Calginat
Kalrostat 2
Alginic Acid, Potassium Salt
Barium Alginate
Copper Alginate
Vocoloid
Alginic Acid, Copper Salt
Alginic Acid, Barium Salt
Kalrostat
Kaltostat

Salts and esters of ALGINIC ACID that are used as HYDROGELS; DENTAL IMPRESSION MATERIALS, and as absorbent materials for surgical dressings (BANDAGES, HYDROCOLLOID). They are also used to manufacture MICROSPHERES and NANOPARTICLES for DIAGNOSTIC REAGENT KITS and DRUG DELIVERY SYSTEMS.


Convulsive Therapy
Therapy, Convulsive
Insulin Shock Therapy
Therapy, Insulin Coma
Coma Therapy, Insulin
Therapy, Insulin Shock
Insulin Coma Therapy
Therapy, Shock
Shock Therapy
Shock Therapy, Insulin

Convulsions induced in order to treat MENTAL DISORDERS. It is used primarily in the treatment of severe affective disorders and SCHIZOPHRENIA.


Amino Acid Transport System XAG
Glutamate Translocase
Glutamate Transport Glycoprotein
Glutamate Transporter
Amino Acid Transport System X-AG
Glutamate-Aspartate Transporter
GLAST Glutamate-Aspartate Transporters

A family of POTASSIUM and SODIUM-dependent acidic amino acid transporters that demonstrate a high affinity for GLUTAMIC ACID and ASPARTIC ACID. Several variants of this system are found in neuronal tissue.


Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis

Muscle-Specific Receptor Tyrosine Kinase Myasthenia Gravis

A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.


Heart Injuries
Injuries, Heart
Heart Rupture, Traumatic
Cardiac Rupture, Traumatic

General or unspecified injuries to the heart.


Guinea Worm
Medina Worm
Dracunculus Nematode
Dracunculus medinensis

A genus of nematode parasites which inhabit the body cavity, serous membranes, and connective tissues of vertebrates. The parasitic species in humans is Dracunculus medinensis.


Streptomycin Grünenthal
Streptomycin Sulfate
Estreptomicina Clariana
Estreptomicina CEPA
Strepto-Fatol
Strepto-Hefa
Estreptomicina Normon
Streptomycin
Streptomycine Panpharma
Streptomycin Sulphate
Streptomycin Sulfate (2:3) Salt

An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.


Crotonates
2-Butenoic Acids
Crotonic Acids

4-Carbon monounsaturated monocarboxylic acids with the unsaturation in the 2 position.


Leprosy, Lepromatous
Leprosy, Cutaneous
Leprosy, Nodular

A chronic communicable infection which is a principal or polar form of LEPROSY. This disorder is caused by MYCOBACTERIUM LEPRAE and produces diffuse granulomatous skin lesions in the form of nodules, macules, or papules. The peripheral nerves are involved symmetrically and neural sequelae occur in the advanced stage.


Allium schoenoprasum
Chinese Chive
Chives
Chive
Allium tuberosum

A plant in the genus ALLIUM, similar to ONIONS.


Immunologic Desensitization
Allergen Immunotherapy
Hyposensitization Therapy
Desensitization, Immunologic
Therapy, Hyposensitization
Immunotherapy, Allergen

Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.


Lansing Virus
Leon Virus
Poliovirus Type 3
Polioviruses
Human poliovirus 1
Poliovirus
Human poliovirus 3
Poliovirus Type 1
Poliovirus Type 2
Human poliovirus 2
Brunhilde Virus

A species of ENTEROVIRUS which is the causal agent of POLIOMYELITIS in humans. Three serotypes (strains) exist. Transmission is by the fecal-oral route, pharyngeal secretions, or mechanical vector (flies). Vaccines with both inactivated and live attenuated virus have proven effective in immunizing against the infection.


Assay for Transposase-Accessible Chromatin Using Sequencing

Chromatin Immuno-Precipitation Paired-End Tag

High-Throughput Sequencing of RNA Isolated by Crosslinking Immunoprecipitation

Chromatin Immunoprecipitation Paired-End Tag

Cross-Linking and Immunoprecipitation Followed by Deep Sequencing

A technique for identifying the BINDING SITES on nucleic acid sequences that are associated with binding proteins.


Drug-Related Side Effects and Adverse Reactions

Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.


Peptide Mapping
Fingerprints, Peptide
Fingerprints, Protein
Protein Fingerprinting
Peptide Fingerprinting

Analysis of PEPTIDES that are generated from the digestion or fragmentation of a protein or mixture of PROTEINS, by ELECTROPHORESIS; CHROMATOGRAPHY; or MASS SPECTROMETRY. The resulting peptide fingerprints are analyzed for a variety of purposes including the identification of the proteins in a sample, GENETIC POLYMORPHISMS, patterns of gene expression, and patterns diagnostic for diseases.


Shiatsu
Shiatzu
Chih Ya
Acupressure
Zhi Ya

A type of massage in which finger pressure on specific body sites is used to promote healing, relieve fatigue, etc. Although the anatomical locations are the same as the ACUPUNCTURE POINTS used in ACUPUNCTURE THERAPY (hence acu-), no needle or other acupuncture technique is employed in acupressure. (From Random House Unabridged Dictionary, 2d ed). Shiatsu is a modern outgrowth that focuses more on prevention than healing.


Amobarbital Sodium
Pentymal
Neur-Amyl
Amsal
Isoamitil Sedante
Amobarbital
Sodium Amobarbital
Amylobeta
Amytal
Eunoctal
Sodium Amytal
Amylbarb sodium
Amylobarbitone
Barbamyl
Transital
Novamobarb
Placidel
Amytal Sodium
Isonal

A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)


Sodium 2-Mercaptoethanesulphonate
UCB-3983
Mucofluid
Uromitexan
Mistabronco
MESNA-cell
Mesna
Mesnex
Coenzyme M
Mitexan
2-Mercaptoethanesulfonate
Mistabron
Mesnum
Ziken
ASTA-D 7093

A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.


Plasma Membrane Calcium-Transporting ATPase 3

Plasma Membrane Calcium-Transporting ATPases

Plasma Membrane Ca(2+)-Pumping Adenosinetriphosphatase

Calcium-Transporting ATPases, Plasma Membrane

Plasma Membrane Calcium-Transporting ATPase 1

Plasma Membrane Calcium-Transporting ATPase 2

Plasma Membrane Calcium-Transporting ATPase 4

Calcium-transporting ATPases found on the PLASMA MEMBRANE that catalyze the active transport of CALCIUM from the CYTOPLASM into the extracellular space. They play a role in maintaining a CALCIUM gradient across plasma membrane.


Costal Margin
Rib Cage
Ribcage
Costal Arch
Thoracic Cage
Rib Margin

The bony thoracic enclosure consisting of the vertebral column; the RIBS; the STERNUM; and the COSTAL CARTILAGE.


Sodium Channel, Voltage-Gated, Type I, alpha Protein

Voltage-Gated Sodium Channel Type 1 Subunit alpha

Voltage-Gated Sodium Channel Type 1 alpha Subunit

A voltage-gated sodium channel subtype that is predominantly expressed in the CENTRAL NERVOUS SYSTEM. Defects in the SCN1A gene which codes for the alpha subunit of this sodium channel are associated with DRAVET SYNDROME, generalized epilepsy with febrile seizures plus, type 2 (GEFS+2), and familial hemiplegic migraine type 3.


M Phase
Cell Division
Cell Division Phase
Cell Divisions

The period of the cell cycle when CELLS divide their nucleus and cytoplasm.


A non-peptide, kappa-opioid receptor agonist which has also been found to stimulate the release of adrenocorticotropin (ADRENOCORTICOTROPIC HORMONE) via the release of hypothalamic arginine vasopressin (ARGININE VASOPRESSIN) and CORTICOTROPIN-RELEASING HORMONE. (From J Pharmacol Exp Ther 1997;280(1):416-21)


Hoe-40045
Carticain
Ultracaine
Carticaine Hydrochloride
Articaine
Hoe-045
Carticaine
Articain

A thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.


A variant within a species of microorganisms with a specific combination of antigens.


Taurocholate
Taurocholate Sodium
Taurocholic Acid, (7 beta)-Isomer
Cholyltaurine
Sodium Taurocholate
Taurocholic Acid, (5 alpha)-Isomer
Taurocholic Acid
Taurocholic Acid, Monosodium Salt
Taurine Cholate
Taurocholic Acid, Monolithium Salt

The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.


p-Aminobenzoic Acid
Pabasan
Magnesium para-Aminobenzoate
Paraminan
Aminobenzoic Acid (USP)
Potassium Aminobenzoate
Paraminol
4-Aminobenzoic Acid, Potassium Salt
para-Aminobenzoic Acid
PABA
Potassium 4-Aminobenzoate
Hachemina
Potaba
Epit Vit
4-Aminobenzoic Acid
Epitelplast

An aminobenzoic acid isomer that combines with pteridine and GLUTAMIC ACID to form FOLIC ACID. The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in SUNSCREENS.


Chenic Acid
Chenix
Gallodesoxycholic Acid
Henohol
Chenique Acid
Chenodeoxycholic Acid
Chenodeoxycholate
Quenocol
Sodium Chenodeoxycholate
Chenophalk
Chenofalk
Chenodiol
Quenobilan

A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.


Tubal Occlusion
Tubal Occlusion, Chemical
Chemical Tubal Occlusion
Tubal Ligation
Occlusion, Chemical Tubal
Pomeroy Method
Uchida Method
Ligation, Tubal
Nonchemical Tubal Occlusion
Sterilization, Tubal
Cornual Coagulation
Irving Method
Madlener Method
Aldridge Procedure
Kroener Fimbriectomy
Tubal Rings
Cooke Method
Tubal Occlusion, Nonchemical
Pomeroy Sterilization
Fimbriectomy
Occlusion, Nonchemical Tubal
Kroener Method

A fimbriectomy technique that consists of excising the distal tube and fimbriae, and ligating the cut ends of the tube with silk sutures.


Recommended Daily Intake
Recommended Daily Allowance
Dietary Reference Intake
Recommended Dietary Allowance
Reference Daily Intake
Daily Recommended Allowance
Daily Recommended Intake
Recommended Dietary Allowances
Recommended Daily Allowances

The amounts of various substances in the diet recommended by governmental guidelines as needed to sustain healthy life.


A benzamide and indazole derivative that acts as a TYROSINE KINASE inhibitor of the VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR. It is used in the treatment of advanced RENAL CELL CARCINOMA.


Calcium-Calmodulin-Dependent Protein Kinase I Activator

Calcium-Calmodulin-Dependent Protein Kinase Kinase 2

Calcium-Calmodulin-Dependent Protein Kinase Kinase alpha

Calcium-Calmodulin-Dependent Protein Kinase Kinase beta

Calcium-Calmodulin-Dependent Protein Kinase Kinase 1

A regulatory calcium-calmodulin-dependent protein kinase that specifically phosphorylates CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; and PROTEIN KINASE B. It is a monomeric enzyme that is encoded by at least two different genes.


Brain Thrombus
Thrombosis, Intracranial
Cerebral Thrombus
Cerebral Thrombosis
Thrombosis, Brain
Brain Thrombosis
Intracranial Thrombosis
Thrombus, Intracranial

Formation or presence of a blood clot (THROMBUS) in a blood vessel within the SKULL. Intracranial thrombosis can lead to thrombotic occlusions and BRAIN INFARCTION. The majority of the thrombotic occlusions are associated with ATHEROSCLEROSIS.


Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. EC 2.6.1.1.


Vaccines, Subunit
Vaccines, Peptide
Peptide Vaccines

Vaccines consisting of one or more antigens that stimulate a strong immune response. They are purified from microorganisms or produced by recombinant DNA techniques, or they can be chemically synthesized peptides.


Trenbolone
Trenbolone Acetate
Trenbolone Acetate, (17beta)-isomer
17 beta-acetoxyestra-4,9,11-trien-3-one
Trienbolone Acetate
Progro T-S
Trienbolone

An anabolic steroid used mainly as an anabolic agent in veterinary practice.


Fendiline
Sensit
Senzit
Fendilin
Fendiline Hydrochloride

Coronary vasodilator; inhibits calcium function in muscle cells in excitation-contraction coupling; proposed as antiarrhythmic and antianginal agents.


Angiotensin 2 Type 1 Receptor Antagonists

Angiotensin II Type 1 Receptor Antagonists

Selective Angiotensin II Receptor Antagonists

Agents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS.


Avicennia marina
Black Mangrove
Avicennia
Mangrove, Grey

A plant genus of the family Acanthaceae. Members contain NAPHTHOQUINONES. Black mangroves (common name for the genus) are distinguished from other mangroves by their spike-like aerial roots called pneumatophores that project from the soil or water surrounding the plants.


Oxyphenisatin Acetate
Oxyphenisatine
Phenolisatin
Diasatine
Isocrin
Dioxyphenylisatin
Oxyphenisatin
Acetfenolisatin

A laxative that undergoes enterohepatic circulation. It may cause jaundice.


Inferior Pharyngeal Constrictor
Inferior Constrictor of Pharynx
Upper Esophageal Sphincter
Esophageal Sphincter, Upper
Cricopharyngeus
Cricopharyngeus Muscle
Thyropharyngeus

The structure at the pharyngoesophageal junction consisting chiefly of the cricopharyngeus muscle. It normally occludes the lumen of the ESOPHAGUS, except during SWALLOWING.


Hyperglycemia, Postprandial
Hyperglycemia
Postprandial Hyperglycemia

Abnormally high BLOOD GLUCOSE level after a meal.


Polio Encephalitis
Encephalitis, Polio
Poliomyelitis Infection
Polio
Epidemic Acute Poliomyelitis
Poliomyelitis, Preparalytic
Poliomyelitis
Poliomyelitis, Acute
Poliomyelitis, Nonpoliovirus
Infantile Paralysis

An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)


Pleuropneumonia Like Organisms
Mycoplasma
Haemobartonella
Eperythrozoon
Pleuropneumonia-Like Organisms
PPLO
Mycoplasma putrefaciens

A species that is associated with caprine MASTITIS and possesses an intense odor.


Lyovac-Cosmegen
Dactinomycin
Meractinomycin
Actinomycin D
Actinomycin
Cosmegen
Cosmegen Lyovac

A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)


Strawberries
Alpine Strawberry
Woodland Strawberry
Strawberry
Fragaria
Fragaria vesca

A plant genus of the family ROSACEAE known for the edible fruit.


In Vitro Diagnostic Medical Devices
Diagnostic Reagents and Test Kits
Diagnostic Reagent Kits
In Vitro Diagnostic Devices
In Vitro Diagnostic Medical Device
Diagnostic Test Kits
Reagent Kits, Diagnostic
Kits, Diagnostic Reagent
In Vitro Diagnostic Device

Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.


Fasigyn Tricolam CP-12,574 Fasigyne Fasigin Tinidazole Simplotan Fasygin CP-12574 Bioshik

A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.


A cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT.


Acute Exercise
Exercise Training
Exercise, Aerobic
Aerobic Exercise
Isometric Exercise
Physical Activity
Exercise
Exercise, Physical
Exercise, Isometric


Tendons, Paraarticular
Epotenon
Tendons, Para-Articular
Endotenon
Tendons

Fibrous bands or cords of CONNECTIVE TISSUE at the ends of SKELETAL MUSCLE FIBERS that serve to attach the MUSCLES to bones and other structures.


Central Nervous System Inborn Metabolic Diseases

Metabolic Diseases, Inborn, Central Nervous System

Central Nervous System Inborn Metabolic Disorders

Brain disorders resulting from inborn metabolic errors, primarily from enzymatic defects which lead to substrate accumulation, product reduction, or increase in toxic metabolites through alternate pathways. The majority of these conditions are familial, however spontaneous mutation may also occur in utero.


Pneumatic Suits
Antigravity Suits
Military Anti-Shock Trousers
Antishock Trousers
Military Antishock Trousers
Anti-Shock Trousers
Gravity Suits
Pressure Suits

Double-layered inflatable suits which, when inflated, exert pressure on the lower part of the wearer's body. The suits are used to improve or stabilize the circulatory state, i.e., to prevent hypotension, control hemorrhage, and regulate blood pressure. The suits are also used by pilots under positive acceleration.


Bioethics Consultants
Bioethicists
Ethicists, Clinical
Ethics Consultants
Ethicist, Clinical
Ethicists
Clinical Ethicist
Clinical Ethicists

Persons trained in philosophical or theological ethics who work in clinical, research, public policy, or other settings where they bring their expertise to bear on the analysis of ethical dilemmas in policies or cases. (Bioethics Thesaurus)


Mutagenesis, Oligonucleotide-Directed
Mutagenesis, Site-Specific
Mutagenesis, Site-Directed
Site-Directed Mutagenesis
Site-Specific Mutagenesis
Oligonucleotide-Directed Mutagenesis

Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.


Dietary Guidelines
Food Policy
Nutrition Guidelines
Nutrition Policy

Guidelines and objectives pertaining to food supply and nutrition including recommendations for healthy diet.


Sabal serrulata
Serenoa serrulata
Sabal
Serenoa
Serenoa repens

A plant genus in the family ARECACEAE, order Arecales, subclass Arecidae. The fruit or the extract (Permixon) is used for PROSTATIC HYPERPLASIA.


Nymphicus hollandicus
Cacatuidae
Cockatiels
Cockatoos

The smallest species of COCKATOO, Nymphicus hollandicus.


Cardiac Arrest, Sudden
Sudden Cardiac Death
Cardiac Sudden Death
Death, Sudden, Cardiac
Sudden Cardiac Arrest

Sudden suspension of cardiac activity that is usually due to ARRHYTHMIA, in contrast to heart attack (MYOCARDIAL INFARCTION) which occurs due to blockage. The sudden suspension of cardiac activity generally requires RESUSCITATION.


rab4A GTP-Binding Protein
rab4 GTP-Binding Protein
rab4A Protein
rab4 GTP-Binding Proteins
rab4 Protein

A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in recycling of proteins such as cell surface receptors from early endosomes to the cell surface. This enzyme was formerly listed as EC 3.6.1.47.


Carya
Carya illinoensis
Hickory Nuts
Pecans
Hickory Tree
Pecan Tree

A plant genus of the family JUGLANDACEAE that bears edible nuts.


Antistatic Agents
Anti-Static Material
Anti-Static Agents
Antistatic Materials

Substances that do not retain an electrostatic charge.


Lambdoid Synostosis
Oxycephaly
Metopic Synostosis
Craniosynostosis
Craniosynostosis, Type 1
Synostotic Anterior Plagiocephaly
Craniostenosis
Synostotic Posterior Plagiocephaly
Plagiocephaly, Craniosynostosis
Craniosynostoses
Brachycephaly
Sagittal Synostosis
Scaphocephaly
Craniosynostosis, Lambdoidal
Unilateral Coronal Synostosis
Trigonocephaly
Acrocephaly
Plagiocephaly, Synostotic

Premature closing of the lambdoid and coronal sutures.


Rats, Inbred Dahl
Dahl Salt-Resistant Rats
Dahl Hypertensive Rats
Dahl Salt-Sensitive Rats
Dahl Rats

Inbred rats derived from Sprague-Dawley rats and used for the study of salt-dependent hypertension. Salt-sensitive and salt-resistant strains have been selectively bred to show the opposite genetically determined blood pressure responses to excess sodium chloride ingestion.


Thevetia
Thevetia peruviana
Oleander Tree, Yellow
Yellow Oleander Tree

A plant genus of the family APOCYNACEAE. Members contain thevetin.


Tests, Diagnostic
Physical Examination, Preadmission
Hospital Admission Tests
Tests, Routine Diagnostic
Preadmission Physical Examination
Routine Diagnostic Test
Admission Tests, Routine
Admission Tests, Hospital
Test, Routine Diagnostic
Routine Diagnostic Tests
Diagnostic Tests, Routine
Diagnostic Tests
Examination, Preadmission Physical
Diagnostic Test, Routine
Tests, Hospital Admission

Diagnostic procedures, such as laboratory tests and x-rays, routinely performed on all individuals or specified categories of individuals in a specified situation, e.g., patients being admitted to the hospital. These include routine tests administered to neonates.


Biological Aging
Senescence
Aging, Biological
Aging

The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.


Neoplasms, Adrenal Cortex
Adrenal Cortex Cancer
Cancer of Adrenal Cortex
Adrenal Cortex Neoplasms
Adrenocortical Cancer
Cancer of the Adrenal Cortex

Tumors or cancers of the ADRENAL CORTEX.


Receptors, Pituitary Hormone-Regulating Hormone

Receptors, Hypothalamic Release-Inhibiting Hormones

Hypothalamic Release-Inhibiting Hormone Receptors

Hypothalamic Releasing Hormone Receptors

Pituitary Hormone-Regulating Hormone Receptors

Receptors, Pituitary Hormone-Releasing Hormone

Receptors, Hypothalamic Releasing Hormones

Receptors, Pituitary Hormone Release Inhibiting Hormones

Pituitary Hormone-Releasing Hormone Receptors

Cell surface receptors that bind the hypothalamic hormones regulating pituitary cell differentiation, proliferation, and hormone synthesis and release, including the pituitary-releasing and release-inhibiting hormones. The pituitary hormone-regulating hormones are also released by cells other than hypothalamic neurons, and their receptors also occur on non-pituitary cells, especially brain neurons, where their role is less well understood. Receptors for dopamine, which is a prolactin release-inhibiting hormone as well as a common neurotransmitter, are not included here.


Diabetes Mellitus, Experimental
Streptozotocin Diabetes
Experimental Diabetes Mellitus
Alloxan Diabetes
Streptozocin Diabetes

Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.


Phenylalanine Hydroxylase Deficiency Disease, Severe

Deficiency Disease, Phenylalanine Hydroxylase, Severe

Dihydropteridine Reductase Deficiency Disease

Hyperphenylalaninemia Caused by a Defect in Biopterin Metabolism

Deficiency Disease, Dihydropteridine Reductase

Hyperphenylalaninemia, Tetrahydrobiopterin-Deficient, Due To DHPR Deficiency

Quinoid Dihydropteridine Reductase Deficiency

A group of autosomal recessive disorders marked by a deficiency of the hepatic enzyme PHENYLALANINE HYDROXYLASE or less frequently by reduced activity of DIHYDROPTERIDINE REDUCTASE (i.e., atypical phenylketonuria). Classical phenylketonuria is caused by a severe deficiency of phenylalanine hydroxylase and presents in infancy with developmental delay; SEIZURES; skin HYPOPIGMENTATION; ECZEMA; and demyelination in the central nervous system. (From Adams et al., Principles of Neurology, 6th ed, p952).


Repetitive Sequences, Nucleic Acid
DNA Repetitious Region
Genes, Selfish
Direct Repeat
Nucleic Acid Repetitive Sequences
Repetitive Sequence
Repetitious Region, DNA
Selfish DNA
Selfish Genes
DNA, Selfish
Repetitive Region


Diatrizoic Acid Methylglucamine
Triombrin
Reno 60
Amidotrizoic Acid
Renografin M-76
Angiografin
Urografin
Verografin
Gastrografin
Amidotricoic Acid
Renograffin
Renografin
Meglumine Diatrizoate
Triombrast
Gastrograffin
Diatrizoate Meglumine
Gastrographin
Sinografin
Ioxeol
Methylglucamine Diatrizoate
Diatrizoate Methylglucamine
Urografin 76
Urovist
Reno M-Dip
Meglumine Amidotrizoate

A versatile contrast medium used for DIAGNOSTIC X-RAY RADIOLOGY.


DNA Type 1 Topoisomerase Inhibitors
DNA Topoisomerase I Inhibitors
Topoisomerase I Inhibitors
Topoisomerase 1 Inhibitors
Topoisomerase 3 Inhibitors
DNA Topoisomerase III Inhibitors
DNA Type III Topoisomerase Inhibitors
Topoisomerase III Inhibitors

Compounds that inhibit the activity of DNA TOPOISOMERASE I.


Toxoplasmosis, Central Nervous System
Intracranial Toxoplasmosis
Neurotoxoplasmosis
Toxoplasmosis, Cerebral
Central Nervous System Toxoplasmosis
Cerebral Toxoplasmosis

Infections of the BRAIN caused by the protozoan TOXOPLASMA gondii that primarily arise in individuals with IMMUNOLOGIC DEFICIENCY SYNDROMES (see also AIDS-RELATED OPPORTUNISTIC INFECTIONS). The infection may involve the brain diffusely or form discrete abscesses. Clinical manifestations include SEIZURES, altered mentation, headache, focal neurologic deficits, and INTRACRANIAL HYPERTENSION. (From Joynt, Clinical Neurology, 1998, Ch27, pp41-3)


Diet Drinks
Artificially Sweetened Beverages
Diet Beverages

Beverages sweetened with SWEETENING AGENTS that are synthetic or artificial as opposed to naturally-occurring. Examples of sweetening agents include ASPARTAME, sucralose, and saccharin.


Transgenic Organisms
Organisms, Genetically Engineered
Organisms, Transgenic
Organisms, Genetically Modified
Genetically Modified Organisms
Genetically Modified Organism
Modified Organism, Genetically
Organism, Transgenic
Genetically Engineered Organisms
GMO Organisms
GMO Organism
Organism, Genetically Modified

Organisms that have had genes from other species inserted into their genome.


A plant genus of the family BIXACEAE that contains bixin and is the source of annatto food coloring.


Starch Branching Enzyme
1,4-alpha-Glucan Branching Enzyme
Branching Glycosyltransferase
Branching Enzyme
Q-Enzyme
Amylopectin Branching Enzyme
Glycogen Branching Enzyme

In glycogen or amylopectin synthesis, the enzyme that catalyzes the transfer of a segment of a 1,4-alpha-glucan chain to a primary hydroxy group in a similar glucan chain. EC 2.4.1.18.


Butirosin A
Butirosins
Butirosin Sulfate, Anhydrous
Butirosin B
Butirosin Sulfate
Butirosin Sulphate
Butirosin

A water-soluble aminoglycosidic antibiotic complex isolated from fermentation filtrates of Bacillus circulans. Two components (A and B) have been separated from the complex. Both are active against many gram-positive and some gram-negative bacteria.


Comprehensive Health Planning
Review, Appropriateness
Appropriateness Review
Areawide Planning
Annual Implementation Plans
Regional Health Planning

Planning for health resources at a regional or multi-state level.


Recombinant Human Growth Hormone (Mammalian)

Mammalian-cell derived recombinant human growth hormone.


Quasispecies
Quasi-Species
Viral Quasispecies
Viral Quasi-Species

Variations among a population of a given species due to errors in replication of the genome that result in a distribution of non-identical members.


Homologous Recombination Double-Stranded Break DNA Repair

Repair of DNA DAMAGE by exchange of DNA between matching sequences, usually between the allelic DNA (ALLELES) of sister chromatids.


Indinavir Sulfate
L-735 524
L-735,524
Indinavir
Crixivan
MK-639
Indinavir, Sulfate (1:1)

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability.


White Perch
Micropterus
Dicentrarchus
Sea Bass
Moronidae
Sea Basses
Serranidae
Temperate Basses
Morone americana
Morone
Bass

A species of FISHES with the common name white perch, but actually a kind of BASS.


BW A509U
AZT Antiviral
Retrovir
BWA-509U
3'-Azido-3'-deoxythymidine
AZT, Antiviral
Azidothymidine
AZT (Antiviral)
Zidovudine
3'-Azido-2',3'-Dideoxythymidine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.


Candida
Candida utilis
Monilia
Torulopsis utilis
Candida auris

A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; VULVOVAGINAL CANDIDIASIS; and CANDIDIASIS, ORAL (THRUSH).


Seloken
Spesicor
Betaloc
CGP-2175
Metoprolol Succinate
Betaloc-Astra
Metoprolol Tartrate
Beloc-Duriles
Toprol-XL
Spesikor
Lopressor
Metoprolol
Toprol
Metoprolol CR-XL
H 93-26
Betalok

A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.


Orthopedic Surgery
Orthopedic Surgical Procedures
Orthopedic Rehabilitation Surgery
Orthopedic Procedures
Surgery, Orthopedic

Procedures used to treat and correct deformities, diseases, and injuries to the MUSCULOSKELETAL SYSTEM, its articulations, and associated structures.


Liraglutide
Victoza
NN-2211
Saxenda
NN 2211
NN2211

An analog of GLUCAGON-LIKE PEPTIDE 1 and agonist of the GLUCAGON-LIKE PEPTIDE 1 RECEPTOR that is used as a HYPOGLYCEMIC AGENT and supplemental therapy in the treatment of DIABETES MELLITUS by patients who do not respond to METFORMIN.


Transfusion-Associated Graft Vs. Host Disease

Blood Transfusion-Associated Adverse Reactions

Febrile Non-Hemolytic Transfusion Reaction

Transfusion reaction complications such as delayed suppression of ERYTHROPOIESIS may occur after destruction of autologous RED BLOOD CELLS in Hemolytic Transfusion Reaction.


Collagen Type IV, alpha1 Subunit
Collagen Type IV, alpha1 Chain
Type IV (Basement Membrane) Collagen
7S Collagen
Collagen Type IV, alpha2 Subunit
Type IV Collagen
Collagen Type IV, alpha2 Chain
Collagen Type IV
Procollagen Type IV
alpha1(IV) collagen
Collagen alpha1(IV)
Type IV Procollagen

A stable peptide fragment originating from the N-terminal domain of collagen type IV.


Cafe-au-Lait Spots with Pulmonic Stenosis

Pulmonic Stenosis with Cafe-au-Lait Spots

A syndrome characterized by the presence of PULMONARY STENOSIS; CAFE-AU-LAIT SPOTS; MENTAL RETARDATION; and short stature caused by mutations in the NF1 gene (GENES, NEUROFIBROMATOSIS 1).


Commissura Hippocampi
Fornix, Brain
Commissure of Fornix
Fimbria, Brain
Fimbria-Fornix
Fornix (Brain)
Fornical Commissure
Fimbria (Brain)
Fornix-Fimbria
Dorsal Hippocampal Commissure
Hippocampal Commissure
Fimbria of Hippocampus

Heavily myelinated fiber bundle of the TELENCEPHALON projecting from the hippocampal formation to the HYPOTHALAMUS. Some authorities consider the fornix part of the LIMBIC SYSTEM. The fimbria starts as a flattened band of axons arising from the subiculum and HIPPOCAMPUS, which then thickens to form the fornix.


Cerebral Hemorrhage, Hypertensive
Intracerebral Hemorrhage, Hypertensive
Intracranial Hemorrhage, Hypertensive
Hypertensive Hemorrhage, Intracranial
Hypertensive Hemorrhage, Cerebral

Bleeding within the SKULL that is caused by systemic HYPERTENSION, usually in association with INTRACRANIAL ARTERIOSCLEROSIS. Hypertensive hemorrhages are most frequent in the BASAL GANGLIA; CEREBELLUM; PONS; and THALAMUS; but may also involve the CEREBRAL CORTEX, subcortical white matter, and other brain structures.


Paramyotonia Congenita Without Cold Paralysis

Diseases characterized by MYOTONIA, which may be inherited or acquired. Myotonia may be restricted to certain muscles (e.g., intrinsic hand muscles) or occur as a generalized condition.


Contraceptive Agents
Contraceptive Effects
Contraceptives
Contraceptive Effect

Chemical substances that prevent or reduce the probability of CONCEPTION.


Immune System Process
Immune System Processes
Immune System Phenomenon
Immune System Concepts
Immune System Phenomena

The characteristic properties and processes involved in IMMUNITY and an organism's immune response.


Drug Associated Myopathies
Toxic Myopathies
Myalgia-Arthralgia Syndrome
Drug Related Myopathies
Drug Induced Myopathies
Myotoxicity

Damage to the muscle or its function secondary to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.


Voltage-Gated Sodium Channel Type 10 Subunit alpha

Sodium Channel Protein Type 10 Subunit alpha

A voltage-gated sodium channel subtype that is expressed in nociceptors, including spinal and trigeminal sensory neurons. It plays a role in the transmission of pain signals induced by cold, heat, and mechanical stimuli.


Period Circadian Protein 1
Circadian Clock Protein Period 2
Period Circadian Protein 3
Circadian Clock Protein Period
Circadian Clock Protein Period 1
Period Circadian Protein 2
Circadian Pacemaker Protein Rigui
Period Circadian Proteins
Circadian Clock Protein Period 3
Period Proteins

Circadian rhythm signaling proteins that influence circadian clock by interacting with other circadian regulatory proteins and transporting them into the CELL NUCLEUS.


Programmable Implantable Insulin Pump
Pancreas, Artificial Endocrine
Insulin Infusion Systems
beta Cell, Artificial
Insulin Pump, Programmable Implantable
Implantable Programmable Insulin Pump
Pump, Programmable Implantable Insulin

Portable or implantable devices for infusion of insulin. Includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic glucose sensor.


Mitosis
Mitotic M Phase
M Phase, Mitotic

A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species.


Safety-Based Biomedical Device Withdrawals

Removal of a MEDICAL DEVICE from the market due to the identification of an intrinsic property of the device that results in a serious risk to public health.


A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.


Somatomotor Areas
Primary Motor Cortex
Motor Area
Precentral Motor Area
Somatic Motor Areas
Secondary Motor Areas
Supplementary Motor Area
Premotor Area
Motor Cortex
Secondary Motor Cortex
Precentral Motor Cortex
Motor Strip
Primary Motor Area
Premotor Cortex

A thin band of cells on the posterior portion of the precentral gyrus. It forms a parallel band just anterior to primary motor cortex, and the supplementary motor area occupies the central portion of the premotor cortex, along the midline surface of both hemispheres.


Medical Imaging
Imaging, Diagnostic
Imaging, Medical
Diagnostic Imaging

Any visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. It includes measuring physiologic and metabolic responses to physical and chemical stimuli, as well as ultramicroscopy.


Sweetgums
Liquidambar styraciflua
Sweet Gum Trees
Liquidambar
Sweet Gum
Sweetgum

A plant genus of the family HAMAMELIDACEAE. The sap is a source of storax, which should not be confused with the similar named STYRAX genus.


Radiogenic Isotopes
Daughter Nuclides
Radioisotopes
Radioactive Isotopes
Radionuclides
Daugter Isotopes

Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


Anterior Chamber Associated Immune Deviation

Phenomenon which occurs in certain tissue sites and organs (e.g., the ANTERIOR CHAMBER and CORNEA of the eye, brain PARENCHYMAL TISSUE and fetus) to tolerate a known antigen, thereby suppressing the inflammatory immune response. Foreign tissue grafts survive for prolonged periods when placed within such immune privileged sites and organs.


Reproductive Techniques
Technology, Reproductive
Reproductive Technologies
Reproduction Technics
Reproductive Technology
Reproduction Techniques

Methods pertaining to the generation of new individuals, including techniques used in selective BREEDING, cloning (CLONING, ORGANISM), and assisted reproduction (REPRODUCTIVE TECHNIQUES, ASSISTED).


Anabolic Agents
Anabolic Effects
Anabolic Effect

These compounds stimulate anabolism and inhibit catabolism. They stimulate the development of muscle mass, strength, and power.


Epilepsy, Benign Frontal, Childhood
Frontal Epilepsy, Benign, Childhood
Benign Frontal Childhood Epilepsy
Frontal Lobe Epilepsy
Epilepsy, Orbito-Frontal
Epilepsy, Frontal Lobe
Epilepsy, Supplementary Motor
Epilepsy, Cingulate
Childhood Benign Frontal Epilepsy
Epilepsy, Opercular
Epilepsy, Anterior Fronto-Polar

A localization-related (focal) form of epilepsy characterized by seizures which arise in the FRONTAL LOBE.


Texturized Soy Protein
Tofu
Tempeh
Natto
Bean Curd, Soy
Texturized Vegetable Protein
Miso
Soy Foods
Soy Sauce
Soy Cheese


Measurement of the degree of darkening of X-ray film by means of a photocell which measures light transmission through the film.


Ambient Assisted Living
Ambient Intelligence
Ambient-Assisted Living

An emerging paradigm in which people are empowered through intelligent (digital) tools embedded in the surrounding environment. These tools proactively support human existence by being sensitive, adaptive, and responsive to the needs, habits, gestures, and emotions of individuals.


Diuretic Effects
Diuretic Effect
Diuretics
Diuretic

Agents that promote the excretion of urine through their effects on kidney function.


Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 3

Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 4

Hyperpolarization Cyclic-Nucleotide Gated Ion Channels

Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2

Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 1

Potassium-Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2

Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium.


Chromosome Replication Pattern, Temporal

The temporal order in which the DNA of the GENOME is replicated.


L-Protein, Glycine Decarboxylase Complex

A flavoprotein containing oxidoreductase that catalyzes the reduction of lipoamide by NADH to yield dihydrolipoamide and NAD+. The enzyme is a component of several MULTIENZYME COMPLEXES.


Gardens
Plant Nurseries
Nurseries, Plant

Places provided for the cultivation and/or display of PLANTS.


Parasympathomimetic Agents
Parasympathomimetic Drugs
Parasympathomimetic Effect
Parasympathomimetic Effects
Parasympathomimetics

Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.


Fruit, Miracle
Synsepalum
Miracle Fruit
Synsepalum dulcificum

A plant genus of the family SAPOTACEAE. Members contain miraculin (also spelled mieraculin), a sweet protein.


Vomacur
Dramamine
Aviomarin
Calm-X
Dramanate
Dimen Heumann
Reisetabletten-ratiopharm
Vomex A
Dimen Lichtenstein
Superpep
Apo-Dimenhydrinate
Reisegold
Reisetabletten Lünopharm
Dinate
Wehamine
Vomisin
Gravol
Dimenhydrinate
Reisetabletten Stada
Travel Well
Contramareo
Cinfamar
TripTone
DMH
Biodramina
Marmine
Rodovan
Vertigo-Vomex
Diphenhydramine Theoclate
RubieMen
Dimetabs
Motion-Aid
Nausicalm

A drug combination that contains diphenhydramine and theophylline. It is used for treating VERTIGO, MOTION SICKNESS, and NAUSEA associated with PREGNANCY.


Genes, src
v-src Genes
v-src Oncogenes
src Genes
c-src Proto-Oncogenes
c-src Genes
src Oncogene
src Gene

Retrovirus-associated DNA sequences (src) originally isolated from the Rous sarcoma virus (RSV). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20.


Neurotransmitter Transport Proteins, GABA-Specific

Gamma-Aminobutyric Acid Plasma Membrane Transport Proteins

GABA Plasma Membrane Transporter Proteins

A family of plasma membrane neurotransmitter transporter proteins that regulates extracellular levels of the inhibitory neurotransmitter GAMMA-AMINOBUTYRIC ACID. They differ from GABA RECEPTORS, which signal cellular responses to GAMMA-AMINOBUTYRIC ACID. They control GABA reuptake into PRESYNAPTIC TERMINALS in the CENTRAL NERVOUS SYSTEM through high-affinity sodium-dependent transport.


Treatment Delay
Delayed Treatment
Time-to-Treatment
Door-to-Treatment Time
Time to Treatment

The interval of time between onset of symptoms and initiation of therapy.


Computer Systems Evaluation
Computer Architecture
Computer Systems
Real-Time Systems
Computer Systems Organization
Organization, Computer Systems
Computer Systems Development

Systems composed of a computer or computers, peripheral equipment, such as disks, printers, and terminals, and telecommunications capabilities.


pH gradient
Proton-Motive Force
Chemiosmotic Mechanisms
delta pH
deltapH

Change in HYDROGEN-ION CONCENTRATION across a membrane. The pH gradient together with the voltage gradient constitute an electrochemical proton gradient which exerts the PROTON-MOTIVE FORCE.


In Situ Hydrogels
Hydrogel
Patterned Hydrogels
In Situ Hydrogel
Hydrogels
Patterned Hydrogel

Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)


Carum carvi
Carum copticum
Ajowan
Carum
Caraway

A plant genus of the family Apiaceae. The seeds are used as flavoring.


A plant genus of the family APOCYNACEAE. Members contain echitovenidine, echitamine, venenatine (an indole alkaloid), and anti-inflammatory triterpenoids


Nucleobindins
CALNUC
CALNUC protein
Nucleobindin
Nucleobindin-1 protein

A DNA and calcium binding protein which plays a role in calcium homeostasis.


Postoperative Vasoplegic Syndrome
Vasoplegia
Vasoplegic Syndrome
Post-operative Vasoplegic Syndrome

Condition of low SYSTEMIC VASCULAR RESISTANCE that develops secondary to other conditions such as ANAPHYLAXIS; SEPSIS; SURGICAL SHOCK; and SEPTIC SHOCK. Vasoplegia that develops during or post surgery (e.g., CARDIOPULMONARY BYPASS) is called postoperative vasoplegic syndrome or vasoplegic syndrome.


Anti-Carcinogenic Drugs
Anti-Carcinogenic Effect
Anticarcinogenic Effects
Anticarcinogens
Anticarcinogenic Drugs
Anticarcinogenic Agents
Anti-Carcinogenic Agents
Anticarcinogenic Effect
Anti-Carcinogenic Effects

Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.


Coxa Vara
Congenital Coxa Vara
Acquired Coxa Varus
Coxa Varus
Coxa Vara, Congenital
Infantile Coxa Vara
Developmental Coxa Vara
Developmental Coxa Varus
Acquired Coxa Vara
Congenital Coxa Varus

Hip deformity in which the femoral neck leans forward resulting in a decrease in the angle between femoral neck and its shaft. It may be congenital often syndromic, acquired, or developmental.


Unilamellar Liposomes
Unilamellar Vesicles
Monolayer Vesicles
Monolayer Liposomes

Single membrane vesicles, generally made of PHOSPHOLIPIDS.


Neoplastic Cells, Circulating
Embolism, Tumor
Circulating Cells, Neoplasm
Neoplasm Circulating Cells
Circulating Neoplastic Cells
Circulating Tumor Cells
Tumor Cells, Embolic
Cells, Neoplasm Circulating
Embolic Tumor Cells

Exfoliate neoplastic cells circulating in the blood and associated with metastasizing tumors.


Spatial Processing
Visual Spatial Processing
Auditory Spatial Processing
Auditory-Visual Spatial Processing
Visual-Auditory Spatial Processing

Integration of spatial information perceived by visual and/or auditory CUES.


Pitcherplant Darlingtonia Sarraceniaceae Flytrap Sarracenia


Posterior Commissure, Laryngeal
Laryngeal Posterior Commissure
Laryngeal Anterior Commissure
Anterior Commissure, Laryngeal
Anterior Commissure, Larynx
Larynx
Posterior Commissure, Larynx

A tubular organ of VOICE production. It is located in the anterior neck, superior to the TRACHEA and inferior to the tongue and HYOID BONE.


Delirium, Dementia, Amnestic, Cognitive Disorders

Cognitive disorders including delirium, dementia, and other cognitive disorders. These may be the result of substance use, trauma, or other causes.


Antibiosis
Interference, Bacterial
Microbial Antagonism
Bacterial Interference

A natural association between organisms that is detrimental to at least one of them. This often refers to the production of chemicals by one microorganism that is harmful to another.


Clock, Biologic
Oscillators, Endogenous
Pacemakers, Biological
Biological Oscillators
Biologic Clock
Clocks, Biological
Biologic Oscillator
Oscillators, Biological
Biological Pacemakers
Pacemakers, Biologic
Pacemaker, Biologic
Oscillator, Biologic
Biological Clocks

The physiological mechanisms that govern the rhythmic occurrence of certain biochemical, physiological, and behavioral phenomena.


Angiotensin Receptor Blockers
Angiotensin II Receptor Antagonists
Angiotensin II Receptor Blockers
Angiotensin Receptor Antagonists

Agents that antagonize ANGIOTENSIN RECEPTORS. Many drugs in this class specifically target the ANGIOTENSIN TYPE 1 RECEPTOR.


Tabloid
Thioguanine
Thioguanine Anhydrous
Lanvis
Thioguanine Hemihydrate
Tioguanine
2-Amino-6-Purinethiol
Thioguanine Tabloid
Thioguanine Monosodium Salt
6-Thioguanine
Tioguanina Wellcome
Thioguanin-GSK

An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.


Diplotene Stage
Meiotic Prophase 1
Diakinesis
Zygotene Stage
Zygonema
Prophase 1
Diplonema
Meiotic Prophase I
Leptotene Stage
Prophase I

The first stage of meiotic prophase I when the CHROMOSOMES first become visible. Also called leptonema. Distinguish from the genus Leptonema.


Chronic Liver Failure
Liver Failure, Chronic
End Stage Liver Disease

Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed.


Bouillaud Disease
Bouillaud's Disease
Rheumatic Heart Disease

Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.


Surgical Procedures, Arthroscopic
Arthroscopic Surgery
Arthroscopic Surgical Procedures
Surgery, Arthroscopic
Arthroscopy

Endoscopic examination, therapy and surgery of the joint.


Tree Bark
Plant Bark
Bark, Tree
Bark, Plant

The outer layer of the woody parts of plants.


Monoamine Oxidase A
MAO-A
Amine Oxidase (Flavin-Containing)
Monoamine Oxidase B
MAO-B
MAO
Monoamine Oxidase
Type A Monoamine Oxidase
Type B Monoamine Oxidase
Tyramine Oxidase

An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4.


Acrinol
Neo Chinosol
Metifex
Uroseptol
Rimaon
Rivanol
Ethacridine
Ethodin
Acrolactine
Ethacridine Lactate
Ethacridine Lactate, Monohydrate
Ethacridine Monohydrate
2,5-Diamino-7-ethoxyacridine

A topically applied anti-infective agent.


A morpholine derivative that is a selective and potent noradrenaline reuptake inhibitor; it is used in the treatment of DEPRESSIVE DISORDER.


History, 16th Century
16th Cent. History of Medicine
16th Century History
Historical Events, 16th Century
Medical History, 16th Cent.
Medicine, 16th Cent.
16th Cent. History (Medicine)
History of Medicine, 16th Cent.
History, Sixteenth Century
16th Cent. Medicine

Events of lasting impact or importance occurring in the 16th century.


Prolactin-Releasing Peptide PrRP20
PrRP31
Prolactin-Releasing Peptide
Prolactin-Releasing Hormone
PrRP20
Prolactin-Releasing Peptide PrRP31

A hypothalamic hormone that is synthesized as a precursor protein which is cleaved into two peptides. In addition to stimulating PROLACTIN release the peptides bind to specific G-PROTEIN-COUPLED RECEPTORS found at locations within the BRAIN.


High-Frequency Positive Pressure Ventilation

High Frequency Positive Pressure Ventilation

Ventilatory support system using frequencies from 60-900 cycles/min or more. Three types of systems have been distinguished on the basis of rates, volumes, and the system used. They are high frequency positive-pressure ventilation (HFPPV); HIGH-FREQUENCY JET VENTILATION; (HFJV); and high-frequency oscillation (HFO).


WDSV
WEHV-1
Walleye dermal sarcoma virus
Epidermal Hyperplasia Virus 2, Walleye
Sarcoma Virus, Walleye Dermal
Epidermal Hyperplasia Virus 1, Walleye
Walleye epidermal hyperplasia virus 2
Epsilonretrovirus
WEHV-2
Walleye epidermal hyperplasia virus 1


Accidental Release, Chemical
Chemical Hazard Release
Incidents, Chemical
Accidents, Chemical

Non-deliberate uncontrolled release of a chemical from its containment.


Newsletters
Journals as Topic
Magazines
Periodicals as Topic

Works about publications issued at stated, more or less regular, intervals.


Stenoses, Pulmonary Valve
Pulmonary Stenoses
Valvular Pulmonic Stenosis
Pulmonic Stenosis
Stenosis, Pulmonary
Stenosis, Pulmonary Valve
Stenoses, Pulmonary
Pulmonary Valve Stenosis
Pulmonary Valve Stenoses
Pulmonary Stenosis

The pathologic narrowing of the orifice of the PULMONARY VALVE. This lesion restricts blood outflow from the RIGHT VENTRICLE to the PULMONARY ARTERY. When the trileaflet valve is fused into an imperforate membrane, the blockage is complete.


CIK Cells
Cytokine-Induced Killer Cells
Lymphocyte-Activated Killer Cell
Lymphocyte-Activated Killer Cells

Mononuclear leukocytes that have be expanded in CELL CULTURE and activated by co-culturing with cells that express CYTOKINES such as INTERLEUKIN-2 to produce large numbers of highly cytotoxic cells.


Glucose, (DL)-Isomer
Glucose, (beta-D)-Isomer
Anhydrous Dextrose
Glucose
Glucose, (L)-Isomer
D-Glucose
Glucose, (alpha-D)-Isomer
L-Glucose
Glucose Monohydrate
Dextrose

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.


Adrenocorticotropic Hormone, Inappropriate Secretion

Inappropriate Adrenocorticotropic Hormone Secretion

A disease of the PITUITARY GLAND characterized by the excess amount of ADRENOCORTICOTROPIC HORMONE secreted. This leads to hypersecretion of cortisol (HYDROCORTISONE) by the ADRENAL GLANDS resulting in CUSHING SYNDROME.


Methylmethylergonovine
Methysergide Maleate
UML-491
Methysergide Dimaleate
Desril
Dimethylergometrin
Sansert
Methysergide
Deseril
Désernil-Sandoz

An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.


External Chest Wall Oscillation
High-Frequency Chest Compression
High-Frequency Chest Wall Compression
High-Frequency Chest Wall Oscillation
Chest Wall Oscillation

A respiratory support system that applies high-frequency chest wall oscillation (HFCWO) for airway clearance by removing mucus to enhance pulmonary function.


An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)


Hospital Planning, Regional
Planning, Hospital
Plannings, Hospital
Hospital Plannings, Regional
Regional Hospital Planning
Hospital Planning
Regional Hospital Plannings

Areawide planning for hospitals or planning of a particular hospital unit on the basis of projected consumer need. This does not include hospital design and construction or architectural plans.


Liquaemin
Unfractionated Heparin
Heparin Sodium
Heparinic Acid
alpha-Heparin
Sodium Heparin
Heparin

A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.


n-Hexadecane Polyoxyethylene Glycol Monether

Non-ionic surfactant of the polyethylene glycol family. It is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base, and also as a research tool.


1,3-Propanediol, 2-(2-(2-amino-9H-purin-9-yl)ethyl)-, diacetate (ester)

An aminopurine derivative and prodrug of penciclovir which is a competitive inhibitor of herpes simplex 2 DNA polymerase. It is used to treat HERPES SIMPLEX VIRUS INFECTION.


Formyltransferases
Formyl Transferases
Hydroxymethyl and Formyl Transferases
Transhydroxymethylases
Hydroxymethyl Transferases
Transformylases
Hydroxymethyltransferases
Transformylase

Enzymes that catalyze the transfer of hydroxymethyl or formyl groups. EC 2.1.2.


Pathologic Calcification
Calcinosis, Tumoral
Microcalcinosis
Microcalcification
Calcification, Pathologic
Calcinosis

An extremely rare benign condition characterized by large calcified periarticular soft tissue masses composed of calcium salts, usually located around large joints. Tumoral calcinosis can occur due to HYPERPHOSPHATEMIA in patients with UREMIA and/or who are undergoing RENAL DIALYSIS.


Typing Technics, Mycological
Mycological Biotyping
Typing Technique, Mycological
Mycological Typing Technics
Typing, Fungal
Mycological Typing Technique
Mycological Typing Technic
Typing Technic, Mycological
Typing Techniques, Mycological
Fungal Typing Techniques
Biotyping, Mycological
Technique, Mycological Typing
Fungal Typing Technics
Technics, Mycological Typing
Techniques, Mycological Typing
Technic, Mycological Typing
Mycological Typing Techniques

Procedures for identifying types and strains of fungi.


Lipotes vexillifer
Orcaella brevirostris
Peponocephala electra
Pontoporia blainvillei
Many-Toothed Blackfish
Risso's Dolphin
Dolphins
Pacific White-Sided Dolphins
Cephalorhynchus
White-Beaked Dolphins
Melon-Headed Whale
Whale, Melon-Headed
Steno bredanensis
Right Whale Dolphins
La Plata Dolphin
Baiji
Feresa attenuata
Sousa
Whale, Pygmy Killer
Delphinidae
Pseudorca crassidens
Amazon Dolphins
Chinese River Dolphin
Marine Dolphins
Franciscana
Amazon River Dolphins
Lagenorhynchus albirostris
Inia geoffrensis
Gray Grampus
Fraser's Dolphin
Pygmy Killer Whale
Irrawaddy River Dolphin
Ganges River Dolphin
Lagenorhynchus acutus
False Killer Whale
Tucuxi Dolphin
Lissodelphis
Lagenorhynchus
Ganges Dolphin
Yangtze River Dolphin
Humpback Dolphins
Sotalia fluviatilis
Whale, False Killer
Platanista
Piebald Dolphins
Grampus griseus
Atlantic White-Sided Dolphins
Susus
Langenorhynchus obliquidens
Ocean Dolphins
Rough-Toothed Dolphin
Planista gangetica
Lagenodelphis hosei

Mammals of the families Delphinidae (ocean dolphins), Iniidae, Lipotidae, Pontoporiidae, and Platanistidae (all river dolphins). Among the most well-known species are the BOTTLE-NOSED DOLPHIN and the KILLER WHALE (a dolphin). The common name dolphin is applied to small cetaceans having a beaklike snout and a slender, streamlined body, whereas PORPOISES are small cetaceans with a blunt snout and rather stocky body. (From Walker's Mammals of the World, 5th ed, pp978-9)


Anastrepha ludens
Trypetidae
Bactrocera tryoni
Anastrepha suspensa
Fruit Fly, Caribbean
Fruit Fly, Mexican
Bactrocera
Anastrepha
Fruit Fly, Queensland
Tephritidae
Rhagoletis

Genus in the family TEPHRITIDAE that includes the Mexican fruit fly Anastrepha ludens and Caribbean fruit fly Anastrepha suspensa.


6 alpha-Methylprednisolone Sodium Hemisuccinate

Methylprednisolone Hemisuccinate Monosodium Salt

A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.


Nu-Sulindac Clinoril Apo-Sulin Kenalin Copal Novo-Sundac Klinoril Aclin MK-231 Sulindac Sulindal Arthrobid Chibret Arthrocine

A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.


Neoplasm Antigens, Viral
T Antigen
Virus Transforming Antigens
Antigens, Viral, Tumor
T Antigens
Viral T Antigens
Viral Tumor Antigens
T-Antigen
Small T-Antigen
Tumor Antigens, Viral
Antigens, Neoplasm, Viral
Large T-Antigen
Large T Antigen
Small T Antigen

Those proteins recognized by antibodies from serum of animals bearing tumors induced by viruses; these proteins are presumably coded for by the nucleic acids of the same viruses that caused the neoplastic transformation.


Cancer of Lip
Cancer of the Lip
Neoplasms, Lip
Lip Neoplasms
Lip Cancer


Listeria Cerebritis
Listeria Meningoencephalitis
Meningoencephalitis, Listeria
Meningitis, Listeria
Listeria monocytogenes Meningitis

Inflammation of the meninges caused by LISTERIA MONOCYTOGENES infection, usually occurring in individuals under the age of 3 years or over the age of 50 years. It may occur at any age in individuals with IMMUNOLOGIC DEFICIENCY SYNDROMES. Clinical manifestations include FEVER, altered mentation, HEADACHE, meningeal signs, focal neurologic signs, and SEIZURES. (From Medicine 1998 Sep;77(5):313-36)


Nervous System Autoimmune Disease, Experimental

Autoimmune Disease Models, Nervous System

Nervous System Autoimmune Disease Models

Disease Models, Autoimmune, Nervous System

Experimental animal models for human AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM. They include GUILLAIN-BARRE SYNDROME (see NEURITIS, AUTOIMMUNE, EXPERIMENTAL); MYASTHENIA GRAVIS (see MYASTHENIA GRAVIS, AUTOIMMUNE, EXPERIMENTAL); and MULTIPLE SCLEROSIS (see ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL).


Gleditsia japonica
Gleditsia
Fagara horrida

A plant genus of the family FABACEAE that contains gleditsiosides (triterpenoid SAPONINS).


Lice of the genus Phthirus, family Pediculidae. Phthirus pubis, the crab louse, is usually acquired by sexual contact or contact with infected objects. It is found most frequently in the pubic hair, but also on eyebrows, eyelashes, or on the axillary hairs.


Tissue and Organ Procurement
Donor Cards
Required Organ Donation Request
Tissue Procurement
Required Request
Tissue Donation
Organ Procurement
Organ Procurement Systems
Organ Donation

An organ procurement policy based on the requirement that health personnel routinely make inquiry of family members about the possibility of removing organs from a patient who has been declared legally dead.


Menstrual Irregularity
Menstrual Irregularities
Irregular Menstruation
Menstruation, Retrograde
Menstruation Disorders
Hypomenorrhea
Menstruation Disturbances
Irregular Menses
Polymenorrhea

Variations of MENSTRUATION which may be indicative of disease.


Choledochojejunostomy Choledochoduodenostomy Choledochostomy Choledojejunostomies

Surgical formation of an opening (stoma) into the COMMON BILE DUCT for drainage or for direct communication with a site in the small intestine, primarily the DUODENUM or JEJUNUM.


Progressive Muscle Relaxation
Autogenic Training
Progressive Relaxation

Technique based on muscle relaxation during self-hypnotic exercises. It is used in conjunction with psychotherapy.


Hexosaminidase alpha-Subunit Deficiency (Variant B)


Dwarf Sperm Whale
Narwhals
Mesoplodon
Grey Whale
Caperea
Goose-Beaked Whale
Pygmy Sperm Whale
Right Whale, North Atlantic
Eubalaena australis
Ziphiidae
Right Whale, Southern
Beaked Whales
Monodon monoceros
Pygmy Right Whale
Gray Whale
Whales
Giant Bottle-Nosed Whales
Ziphius
Berardius
North Atlantic Right Whale
Eschrichtius robustus

Large marine mammals of the order CETACEA. In the past, they were commercially valued for whale oil, for their flesh as human food and in ANIMAL FEED and FERTILIZERS, and for baleen. Today, there is a moratorium on most commercial whaling, as all species are either listed as endangered or threatened.


Precarious Employment
Employment Insecurity
Marginal Employment
Occupational Status
Employment Termination
Labor Force
Employment Status
Employment
Status, Occupational
Underemployment

The state of being engaged in an activity or service for wages or salary.


Apo-Desipramine
Norpramin
Novo-Desipramine
Pertofran
Pertofrane
Desipramine Hydrochloride
Ratio-Desipramine
Desmethylimipramine
Petylyl
Demethylimipramine
Nu-Desipramine
Pertrofran
Desipramine
PMS-Desipramine

A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.


Neurohemal Organ
Sensory Circumventricular Organs
Circumventricular Organs
Secretory Circumventricular Organs

Highly vascularized and specialized tissues distributed principally along the midline of the VENTRICULAR SYSTEM from the FOREBRAIN to the HINDBRAIN. They are distinguished by their lack of normal BLOOD-BRAIN BARRIER and fenestrated capillaries and contain either neurosecretory neurons or chemoreceptors.


Inhalation Devices
Vaporizers and Nebulizers
Nebulizers and Vaporizers
Inhalators
Vaporizers
Atomizers
Nebulizers
Inhalers

Devices that cause a liquid or solid to be converted into an aerosol (spray) or a vapor. It is used in drug administration by inhalation, humidification of ambient air, and in certain analytical instruments.


Poplar, Black
Poplar, Balsam
Populus fremontii
Poplar, True
Populus
Cottonwood
Populus balsamifera
Populus nigra

A plant genus of the family SALICACEAE. Balm of Gilead is a common name used for P. candicans, or P. gileadensis, or P. jackii, and sometimes also used for ABIES BALSAMEA or for COMMIPHORA.


Pueraria lobata
Kudzu
Pueraria montana
Pachyrhizus thunbergianus
Pueraria
Pueraria tuberosa
Puerariae

A plant genus of the family FABACEAE a common weed of the southeast US. There has been folk use for alcoholism and liver protection. It contains puerarin, kakkalide, daidzein (isoflavonoids), and kudzusaponins (oleanene-type triterpene glycosides).


Staphylomycin M
Staphylomycin M1
Pristinamycin IIB
Virginiamycin Factor M1
Streptogramin A
Pristinamycin IIA
Ostreogrycin G
Virginiamycin M1
Virginiamycin IIB

Pristinamycin IIB is identical to Streptogramin A except that it lacks a double bond at the 2,3-position of the pyrroline moiety of the compound.


Medical Device Safety
Device Safety
Hazards, Equipment
Safety, Equipment
Safety, Medical Device
Device Safety, Medical
Equipment Safety

Freedom of equipment from actual or potential hazards.


Patient Nonadherence
Patient Cooperation
Therapeutic Compliance
Patient Compliance
Treatment Compliance
Patient Non-Compliance
Patient Noncompliance
Patient Adherence
Patient Non-Adherence

Voluntary cooperation of the patient in following a prescribed regimen.


A 21-carbon steroid that is converted from PREGNENOLONE by STEROID 17-ALPHA-HYDROXYLASE. It is an intermediate in the delta-5 pathway of biosynthesis of GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.


External Anal Sphincter
Detrusor External Sphincter
Anal Gland
Anal Glands, Human
Anus
Anal Gland, Human
Anal Sphincter
Anal Canal
Internal Anal Sphincter

Large SWEAT GLANDS in the mucous membrane of the ANUS.


Amino Acid Modification, Pretranslational

Pre-Translational Amino Acid Modification

Amino Acid Modification, Co-Translational

Co-Translational Amino Acid Modification

Pretranslational Amino Acid Modification

Amino Acid Modification, Pre-Translational

The enzymatically catalyzed modifications of the amino acid component of an AMINO ACYL TRNA. This includes modifications such as the conversion of the seryl-tRNA to selenocysteinyl-tRNA which is eventually used during GENETIC TRANSLATION in the biosynthesis of selenoproteins.


Online Education
Education, Distance
Online Learning
Correspondence Courses
Distance Learning
Distance Education

Education via communication media (correspondence, radio, television, computer networks) with little or no in-person face-to-face contact between students and teachers. (ERIC Thesaurus, 1997)


DNA Synthesis Inhibitors
Inhibitors, DNA Synthesis
Nucleic Acid Synthesis Inhibitors
DNA Polymerase Inhibitors
Inhibitors, RNA Synthesis
Inhibitors, Nucleic Acid Synthesis
RNA Synthesis Inhibitors

Compounds that inhibit cell production of DNA or RNA.


src Homology Domains
SH1 Domain
SH3 Domain
SH2 Domain
SH Domains
src Homology Region 2 Domain

Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.


Birthing Centers, Free-Standing
Birth Center, Free Standing
Birth Centers
Birthing Centers
Free-Standing Birth Centers
Free Standing Birthing Center

Free-standing facilities that provide prenatal, childbirth, and postnatal care and usually incorporate family-centered maternity care concepts and practices.


Sino-Nasal Outcome Test-22
Sinonasal Outcome Test-22
Sinonasal Outcome Test-20
Sino-Nasal Outcome Test
SNOT-20
Sinonasal Outcome Test
Sino-Nasal Outcome Test-20
SNOT-22

Patient-reported measure of outcome in sino-nasal disorders such as rhinosinusitis and nasal polyposis.


Ataxia
Ataxia, Sensory
Tremor, Rubral
Dyssynergia
Coordination Impairment
Dyscoordination
Ataxia, Motor
Ataxia, Truncal
Lack of Coordination
Incoordination
Ataxy
Ataxia, Appendicular
Ataxia, Limb

Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.


Wechsler Intelligence Scale for Children

Wechsler Adult Intelligence Scale-Revised

Wechsler Preschool and Primary Scale of Intelligence

Tests designed to measure intellectual functioning in children and adults.


Capybaras
Dipodidae
Rodents
Hydrochaeris
Jerboas
Castor Beaver
Beavers
Rodentia

A mammalian order which consists of 29 families and many genera.


Quantitative Real-Time Polymerase Chain Reaction

Methods used for detecting the amplified DNA products from the polymerase chain reaction as they accumulate instead of at the end of the reaction.


Anti-Cholinergics
Cholinergic Antagonists
Acetylcholine Antagonists
Cholinergic Receptor Antagonists
Anticholinergics
Anticholinergic Agents
Cholinergic Antagonist
Cholinergic-Blocking Agents
Cholinolytics

Drugs that bind to but do not activate CHOLINERGIC RECEPTORS, thereby blocking the actions of ACETYLCHOLINE or cholinergic agonists.


Escherichia coli O157-H7
E coli O157-H7
Escherichia coli O157
E coli O157

A verocytotoxin-producing serogroup belonging to the O subfamily of Escherichia coli which has been shown to cause severe food-borne disease. A strain from this serogroup, serotype H7, which produces SHIGA TOXINS, has been linked to human disease outbreaks resulting from contamination of foods by E. coli O157 from bovine origin.


GGF Protein
Neuregulin-1
NDF Protein
Glial Growth Factor
neu Differentiation Factor
NRG1 Protein
Heregulin

A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (RECEPTOR, ERBB-2). It is a ligand for the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Variant forms of NEUREGULIN-1 occur through alternative splicing of its mRNA.


CapZ Actin Capping Protein, alpha Subunit

CapZ Actin Capping Protein, beta Subunit

An actin capping protein that binds to the barbed-ends of ACTIN filaments. It is a heterodimer consisting of an alpha and a beta subunit. It regulates actin assembly by stabilizing actin oligomers for elongation. In SKELETAL MUSCLE, CapZ is localized to the Z-disk.


Serum Albumin, Radio-Iodinated
(131)I-MAA
(131)I-Macroaggregated Albumin
Serum Albumin, Radioiodinated

Normal human serum albumin mildly iodinated with radioactive iodine (131-I) which has a half-life of 8 days, and emits beta and gamma rays. It is used as a diagnostic aid in blood volume determination. (from Merck Index, 11th ed)


Pharyngeal Arches
Visceral Arches
Branchial Clefts
Branchial Region
Pharyngeal Grooves
Branchial Grooves
Pharyngeal Arch
Visceral Arch
Pharyngeal Clefts
Branchial Arch
Branchial Arches

A region, of SOMITE development period, that contains a number of paired arches, each with a mesodermal core lined by ectoderm and endoderm on the two sides. In lower aquatic vertebrates, branchial arches develop into GILLS. In higher vertebrates, the arches forms outpouchings and develop into structures of the head and neck. Separating the arches are the branchial clefts or grooves.


Neuromodulator
Neurotransmitters
Neurotransmitter
Neuromodulators
Transmitter Substances, Nerve
Substances, Nerve Transmitter
Neuroregulator
Neurotransmitter Agent
Neurohumors
Nerve Transmitter Substances
Neurotransmitter Agents
Neuroregulators
Neurohormones

Substances secreted by neurons into the blood, CNS, or intercellular space.


Laminaria
Laminaria japonica
Kombu
Laminaria Tents

A genus of BROWN ALGAE in the family Laminariaceae. Dried pencil-like pieces may be inserted in the cervix where they swell as they absorb moisture, serving as osmotic dilators.


Branchial Clefts with Characteristic Facies, Growth Retardation, Imperforate Nasolacrimal Duct, and Premature Aging

Lip Pseudocleft-Hemangiomatous Branchial Cyst Syndrome

Hemangiomatous Branchial Clefts-Lip Pseudocleft Syndrome

An autosomal dominant disorder manifested by various combinations of preauricular pits, branchial fistulae or cysts, lacrimal duct stenosis, hearing loss, structural defects of the outer, middle, or inner ear, and renal dysplasia. Associated defects include asthenic habitus, long narrow facies, constricted palate, deep overbite, and myopia. Hearing loss may be due to Mondini type cochlear defect and stapes fixation. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed)


Colobini
Procolobus
Piliocolobus
Red Colobus
Colobinae
Olive Colobus

A subfamily of the Old World monkeys, CERCOPITHECIDAE, that inhabits the forests of Africa and Asia. The genera COLOBUS (Procolobus; colobus), Nasalis (proboscis monkey), Presbytis (Semnopithecus; leaf monkey), Pygathrix (Rhinopithecus; snub-nosed monkey), and Simias (pig-tailed langur) all belong to this subfamily.


A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.


Pain Sensation Diminished
Light Touch Sensation Impairment
Thermal Sensation Disorders
Impairment, Light Touch Sensation
Pinprick Sensation Diminished
Proprioceptive Disorders
Position Sense Disorders
Somatosensory Disorders
Somatic Sensation Disorders

Disorders of sensory information received from superficial and deep regions of the body. The somatosensory system conveys neural impulses which pertain to proprioception, tactile sensation, thermal sensation, pressure sensation, and pain. PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD DISEASES; and BRAIN DISEASES may be associated with impaired or abnormal somatic sensation.


Matrilin-3
Matrilin 4
MATN2 Protein
Matrilin-1
Matrilin 2
Matrilins
MATN3 Protein
MATN4 Protein
Matrilin-4
Matrilin Proteins
Cartilage Matrix Protein
Matrilin 1
Matrilin 3
MATN1 Protein
Cartilage Matrix Glycoprotein
Matrilin-2
Cartilage Matrix Proteins

PROTEOGLYCANS-associated proteins that are major components of EXTRACELLULAR MATRIX of various tissues including CARTILAGE; and INTERVERTEBRAL DISC structures. They bind COLLAGEN fibers and contain protein domains that enable oligomer formation and interaction with other extracellular matrix proteins such as CARTILAGE OLIGOMERIC MATRIX PROTEIN.


Genes, Homeo Box
Homeo Box
Homeoboxes
Homeotic Genes
Sequence, Homeo Box
Genes, Homeobox
Homeo Box Sequence
Homeo Boxes
Hox Genes
Homeobox
Genes, Homeotic
Homeobox Sequence

Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.


Raphanus raphanistrum
Raphanus
Raphanus sativus
Radishes
Wild Radish
Cultivated Radish
Garden Radish
Radish

A plant genus of the family BRASSICACEAE known for its peppery red root.


High-Throughput DNA Sequencing
Ion Proton Sequencing
Deep Sequencing
Massively-Parallel Sequencing
High-Throughput RNA Sequencing
High-Throughput Nucleotide Sequencing
Next-Generation Sequencing
Pyrosequencing
Illumina Sequencing
Ion Torrent Sequencing

Techniques of nucleotide sequence analysis that increase the scale of operations enabling an increase in the depth of coverage (number of copies) to which each polynucleotide is sequenced.


Helicobacter heilmannii
Candidatus Helicobacter suis
Helicobacter suis
Gastrospirillum suis
Gastrospirillum hominis


A genus of sphinx or hawk moths of the family Sphingidae. These insects are used in molecular biology studies during all stages of their life cycle.


GroES Stress Protein
Heat-Shock Protein 10
Heat-Shock Proteins 10
Chaperonin 10
hsp10 Protein
GroES Protein
hsp10 Family

A chaperonin 10 heat-shock protein isolated from bacterial sources.


Basal Magnocellular Nucleus
Basal Nucleus of Meynert
Nucleus Basalis Magnocellularis
Nucleus Basalis of Meynert

A group of nerve cells in the SUBSTANTIA INNOMINATA that has wide projections to the NEOCORTEX and is rich in ACETYLCHOLINE and CHOLINE ACETYLTRANSFERASE. In PARKINSON DISEASE and ALZHEIMER DISEASE the nucleus undergoes degeneration.


Long-Beaked Common Dolphin
Common Dolphins
Delphinus delphis
Delphinus
Saddleback Dolphins
Delphinus capensis
Short-Beaked Common Dolphin

The genus Delphinus, in the family Delphinidae, consisting of two species of DOLPHINS. They are multicolored, with a characteristic yellow-tan criss-cross hourglass pattern behind the eyes.


Gluconacetobacter liquefaciens
Gluconacetobacter
Acetobacter liquefaciens


beta-Pyridylcarbinol
Ronicol Retard
Nicomethanol Hydrofluoride
3-Hydroxymethylpyridine
Pyridylcarbinol
Nicotinic Alcohol
Radecol
Ronicol
Roniacol
Nicotinyltartrate
Nicotinyl Alcohol
Pyridine-3-Methanol

Alcohol analog of NICOTINIC ACID which is a direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened GANGRENE.


Idiopathic Minimal Change Nephrotic Syndrome

A kidney disease with no or minimal histological glomerular changes on light microscopy and with no immune deposits. It is characterized by lipid accumulation in the epithelial cells of KIDNEY TUBULES and in the URINE. Patients usually show NEPHROTIC SYNDROME indicating the presence of PROTEINURIA with accompanying EDEMA.


RAD001
RAD 001
SDZ-RAD
Everolimus
40-O-(2-hydroxyethyl)-rapamycin
Afinitor
SDZ RAD
Certican

A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.


P450 CYP3A4 Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 CYP3A5 Inhibitors
P450 CYP3A Inhibitors
CYP3A4 Inhibitors
P450 CYP3A7 Inhibitors
P450 CYP3A5 Inhibitors
CYP3A7 Inhibitors
CYP3A5 Inhibitors
CYP3A Inhibitors
Cytochrome P-450 CYP3A7 Inhibitors
Cytochrome P-450 CYP3A4 Inhibitors

Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP3A.


Woolly Monkey
Brachyteles
Monkey, Woolly Spider
Monkey, Spider
Ateles
Lagothrix
Spider Monkey
Monkey, Woolly
Atelinae

A subfamily in the family ATELIDAE, comprising three genera: woolly monkeys (Lagothrix), spider monkeys (Ateles), and woolly spider monkeys (Brachyteles).


Epithelial Neoplasms
Glandular Neoplasms
Neoplasms, Glandular
Neoplasms, Epithelial
Neoplasms, Glandular Epithelial
Glandular and Epithelial Neoplasms
Neoplasms, Glandular and Epithelial

Neoplasms composed of glandular tissue, an aggregation of epithelial cells that elaborate secretions, and of any type of epithelium itself. The concept does not refer to neoplasms located in the various glands or in epithelial tissue.


Reiter's Disease
Postinfectious Arthritis
Reiter Syndrome
Reiter Disease
Reactive Arthritis
Post-Infectious Arthritis
Arthritis, Postinfectious
Reiter's Syndrome
Arthritis, Post-Infectious
Arthritis, Reactive

Historically characterized by a triad of inflammation involving the eye (CONJUNCTIVITIS), the bone (POST-INFECTIOUS ARTHRITIS), and the urethra (URETHRITIS), it is now thought to be nearly synonymous with reactive arthritis.


Family Planning Services
Family Planning Programs
Pregnancy, Planned
Family Planning
Planned Pregnancy

Health care programs or services designed to assist individuals in the planning of family size. Various methods of CONTRACEPTION can be used to control the number and timing of childbirths.


NP-27
Chlorisept
Tolnaftat Purder N
Curatin
Tinaderm
Ony-Clear
Tinactin
Genaspor
Tineafax
ZeaSorb
Aftate
Chinofungin
Tonoftal
Ting
Micoisdin
Breezee
Sporiline
Tolnaftate
Tinatox


A persistent skin infection marked by the presence of furuncles, often chronic and recurrent. In humans, the causative agent is various species of STAPHYLOCOCCUS. In salmonid fish (SALMONIDS), the pathogen is AEROMONAS SALMONICIDA.


Serogroup W-135, Meningococcal Meningitis

Serogroup W135, Meningococcal Meningitis

Meningitis, Meningococcal, Serogroup W135

Meningitis, Meningococcal, Serogroup W-135

Meningococcal Meningitis, Serogroup W-135

Meningococcal Meningitis, Serogroup W135

A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Organisms from Neisseria meningitidis serogroups A, B, C, Y, and W-135 have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8)


Transurethral Electroresection of Prostate

Transurethral Electrovaporization of Prostate

Transurethral Radiofrequency Thermal Ablation

Transurethral Needle Ablation of Prostate

Transurethral Ultrasound-Guided Laser-Induced Prostatectomy

Transurethral Visual Laser Ablation of Prostate

Removal of all or part of the PROSTATE, often using a cystoscope and/or resectoscope passed through the URETHRA.


Illicium
Star Anise
Illicium verum
Illicium anisatum
Anise, Star

A plant genus of the family SCHISANDRACEAE, order AUSTROBAILEYALES, class MAGNOLIOPSIDA. They have evergreen, aromatic leaves and bisexual flowers. The female portion of the flower consists of 7 to 15 carpels.


An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and glutamine. This enzyme is important in the de novo biosynthesis of pyrimidines. EC 6.3.5.5.


Barbary Ape
Ape, Celebes
Ape, Barbary
Macaque
Celebes Ape
Macaca
Black Ape
Ape, Black

A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of 16 species inhabiting forests of Africa, Asia, and the islands of Borneo, Philippines, and Celebes.


A humanized monoclonal antibody that binds to IL-12 and IL-23 and is used as a DERMATOLOGIC AGENT in the treatment of patients with plaque PSORIASIS who have not responded to other therapies.


HMG Ferring
Pergonal-500
ORG-31338
Menopur
Normegon
Menogon
Gonadotropins, Human Menopausal
CP-90033
HMG Lepori
Humegon
Menotropins
Pergonal
Menotrophin
HMG Massone
CP-89044


Paraesophageal Hiatal Hernia
Hernia, Paraesophageal
Hiatal Hernia
Hernia, Hiatal
Esophageal Hernia
Hernia, Esophageal
Sliding Hiatal Hernia
Sliding Esophageal Hernia
Hernia, Hiatus

A HIATAL HERNIA in which the STOMACH herniation is located alongside the ESOPHAGUS and the ESOPHAGOGASTRIC JUNCTION is in its normal position below the DIAPHRAGM.


Bigfoot
Sasquatch
Yeti, Himalayan
Mermaids
Vampires
Unicorns
Mythical Creatures
Mythical Animals
Legendary Creatures
Werewolves

Mythical blood-sucking humans who rise from the grave at night to prey on the living. Historically, vampire legend dates from ancient times and may be based on persons suffering from RABIES; PELLAGRA; or especially PORPHYRIAS, who exhibit sensitivity to sunlight, abnormal, reddish-brown discoloration of the TEETH, and madness or melancholy disposition. Clinical vampirism includes persons who drink the blood of others or themselves.


Congenital Lobulation of Kidneys
Fused Kidney
Crossed Fused Ectopia
Pelvic Cake Kidney
Fusion of Kidney
Crossed Fused Ectopia of Kidneys
Renal Fusion
Lobulated Kidney
Lobulation of Kidney
Cake Kidney
Horseshoe Kidney
Congenital Fusion of Kidneys

Congenital fusion of two kidneys in the lower midline.


Coma, Post-Concussive
Coma, Traumatic
Coma, Post-Traumatic
Coma, Post-Head Injury
Coma, Post-Traumatic, Prolonged
Post-Head Injury Coma
Coma, Post-Trauma

Prolonged unconsciousness from which the individual cannot be aroused, associated with traumatic injuries to the BRAIN. This may be defined as unconsciousness persisting for 6 hours or longer. Coma results from injury to both cerebral hemispheres or the RETICULAR FORMATION of the BRAIN STEM. Contributing mechanisms include DIFFUSE AXONAL INJURY and BRAIN EDEMA. (From J Neurotrauma 1997 Oct;14(10):699-713)


Norbornenes
Norbornene Derivatives
Norcamphanes
Norbornanes
Norbornane Derivatives

Compounds that include or are derivatives of norbornane(bicyclo[2.2.1]heptane).


CA2 Pyramidal Cell Area
Hippocampus CA2 Field
CA2 Stratum Radiatum
Stratum Radiatum, CA2
CA2 Pyramidal Cell Layer
CA2 Field of Hippocampus
CA2 Region, Hippocampal
Cornu Ammonis 2 Area
CA2 Stratum Pyramidale
Hippocampal Sector CA2

The pyramidal cell layer (stratum pyramidale) of the HIPPOCAMPUS CA2 FIELD.


Perioral Dermatitis
Dermatitis, Perioral
Periocular Dermatitis
Dermatitis, Periocular

A papular eruption of unknown etiology that progresses to residual papular erythema and scaling usually confined to the area of the mouth, and almost exclusively occurring in young women. It may also be localized or extend to involve the eyelids and adjacent glabella area of the forehead (periocular dermatitis). (Dorland, 28th ed)


Greek Letter Societies
College Fraternities
College Fraternities and Sororities
Greek-Letter Societies
Collegiate Fraternities and Sororities
College Sororities
Greek Letter Organizations
Greek-Letter Organizations
Collegiate Fraternities
Collegiate Sororities

Local or national organizations of college students, primarily for social purposes, usually with secret initiations and rites and a name composed of two or three Greek letters.


Respiratory Depression
Respiratory Insufficiency
Ventilatory Depression
Respiratory Failure

Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)


Curling Ulcer
Duodenal Ulcer
Curling's Ulcer

Acute stress DUODENAL ULCER, usually observed in patients with extensive third-degree burns.


Rutledge Lethal Multiple Congenital Anomaly Syndrome

Hyperotosis Corticalis Generalisata Familiaris

Polydactyly, Sex Reversal, Renal Hypoplasia, And Unilobar Lung

An autosomal recessive disorder of CHOLESTEROL metabolism. It is caused by a deficiency of 7-dehydrocholesterol reductase, the enzyme that converts 7-dehydrocholesterol to cholesterol, leading to an abnormally low plasma cholesterol. This syndrome is characterized by multiple CONGENITAL ABNORMALITIES, growth deficiency, and INTELLECTUAL DISABILITY.


Bendamustine Hydrochloride
Cytostasan
Treanda
Zimet 3393
Ribomustin
Bendamustine
Bendamustin
IMET 3393

A nitrogen mustard compound that functions as an ALKYLATING ANTINEOPLASTIC AGENT and is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA and NON-HODGKIN'S LYMPHOMA.


A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.


Short-lived elementary particles found in cosmic radiation or produced from nuclear disintegration. Their mass is between that of protons and electrons and they can be negative, positive, or neutral. pi-Mesons (pions) are heavier than mu-mesons (muons) and are proposed for cancer radiotherapy because their capture and disintegration by matter produces powerful, but short-lived, secondary radiation.


Diagnosis
Examinations and Diagnoses
Diagnoses and Examinations
Antemortem Diagnosis
Postmortem Diagnosis

Diagnosis of a disease or condition made after DEATH.


Macaca fascicularis aurea
Crab-Eating Monkey
Monkey, Crab-Eating
Cynomolgus Monkey
Monkey, Cynomolgus
Crab-Eating Macaque
Burmese Long-Tailed Macaque
Macaca fascicularis
M. fascicularis
M. f. aurea

A species of the genus MACACA which typically lives near the coast in tidal creeks and mangrove swamps primarily on the islands of the Malay peninsula.


Familial Atypical Multiple Mole-Melanoma

Clinically atypical nevi (usually exceeding 5 mm in diameter and having variable pigmentation and ill defined borders) with an increased risk for development of non-familial cutaneous malignant melanoma. Biopsies show melanocytic dysplasia. Nevi are clinically and histologically identical to the precursor lesions for melanoma in the B-K mole syndrome. (Stedman, 25th ed)


Overdiagnosis
Unwanted Medical Care
Overmedication
Overutilization of Health Services
Overuse, Health Services
Medical Preference Misdiagnosis
Preference Misdiagnosis
Health Services Overuse
Medical Overuse
Health Services Overutilization
Overtreatment

Excessive or unnecessary utilization of health services by patients or physicians.


Papilla, Interdental
Gums
Gingiva
Interdental Papilla

Oral tissue surrounding and attached to TEETH.


Cardiovascular Physiology
Cardiovascular Physiologic Processes
Cardiovascular Physiological Phenomena
Cardiovascular Physiological Processes
Cardiovascular Physiological Concepts
Cardiovascular Physiological Phenomenon
Physiology, Cardiovascular
Cardiovascular Physiological Process

Biological actions and events that support the functions of the CARDIOVASCULAR SYSTEM.


Ectosialyltransferase
Glycoprotein Sialyltransferases
Sialyltransferases
Glycoprotein Sialyltransferase

A group of enzymes with the general formula CMP-N-acetylneuraminate:acceptor N-acetylneuraminyl transferase. They catalyze the transfer of N-acetylneuraminic acid from CMP-N-acetylneuraminic acid to an acceptor, which is usually the terminal sugar residue of an oligosaccharide, a glycoprotein, or a glycolipid. EC 2.4.99.-.


A component of the murine major histocompatibility complex class I family. It contains one Ig-like C1-type domain and functions in processing and presentation of exogenous peptide antigens to the immune system.


Adhesin, Bacterial
Adhesins, Bacterial
Bacterial Adhesins
Bacterial Adhesin
Adhesins, Fimbrial
Fimbrial Adhesins

Cell-surface components or appendages of bacteria that facilitate adhesion (BACTERIAL ADHESION) to other cells or to inanimate surfaces. Most fimbriae (FIMBRIAE, BACTERIAL) of gram-negative bacteria function as adhesins, but in many cases it is a minor subunit protein at the tip of the fimbriae that is the actual adhesin. In gram-positive bacteria, a protein or polysaccharide surface layer serves as the specific adhesin. What is sometimes called polymeric adhesin (BIOFILMS) is distinct from protein adhesin.


Guanylate Kinase 1
GMP Kinase
ATP-(d)GMP Phosphotransferase
Membrane-Associated Guanylate Kinase
MAGUK Proteins
Guanylate Kinases
Guanylate Kinase
Guanosine Monophosphate Kinase
Erythrocyte protein p55
Membrane-Associated Guanylate Kinases

Catalyzes the ATP-dependent PHOSPHORYLATION of GMP to generate GDP and ADP.


Thujane Derivatives
Caranes
Pinanes
Bicyclic Monoterpenes
Carane Derivatives
Pinane Derivatives
Camphenes
Thujanes
Camphene Derivatives

Monoterpenes containing two ring structures that are joined either by bridgehead carbon atoms or fused ring structure.