Tick-Borne Encephalitis
European Tick-Borne Encephalitis
Encephalitis, Tick-Borne
Encephalitis, Far Eastern Russian
Encephalitis, Central European
Encephalitis, Louping Ill
Central European Encephalitis
Far Eastern Russian Encephalitis
Powassan Virus Disease
Louping Ill Encephalitis
Russian Spring-Summer Encephalitis
Powassan Encephalitis
Encephalitis, Russian Spring-Summer
Encephalitis, European Tick-Borne

Encephalitis caused by neurotropic viruses that are transmitted via the bite of TICKS. In Europe, the diseases are caused by ENCEPHALITIS VIRUSES, TICK-BORNE, which give rise to Russian spring-summer encephalitis, central European encephalitis, louping ill encephalitis, and related disorders. Powassan encephalitis occurs in North America and Russia and is caused by the Powassan virus. ASEPTIC MENINGITIS and rarely encephalitis may complicate COLORADO TICK FEVER which is endemic to mountainous regions of the western United States. (From Joynt, Clinical Neurology, 1996, Ch26, pp14-5)


Virus Physiological Phenomena
Virus Physiological Process
Virus Physiological Processes
Viral Physiological Phenomena
Viral Physiological Concepts
Viral Physiological Process
Virus Physiology
Physiology, Viral
Viral Physiology
Virus Physiological Concepts
Viral Physiological Processes
Virus Physiological Phenomenon

Biological properties, processes, and activities of VIRUSES, including the interactions with the cells they infect.


Glycoinositol Phospholipid Membrane Anchor

Glycosyl-Phosphatidylinositol Membrane Protein Anchors

Compounds containing carbohydrate or glycosyl groups linked to phosphatidylinositols. They anchor GPI-LINKED PROTEINS or polysaccharides to cell membranes.


MS2 Phage
Coliphage MS2
Enterobacteria phage MS2
Enterobacteria phage f2
Bacteriophage MS2
Enterobacteria phage fr
Enterobacteria phage R17
Phage MS2
Levivirus
Pseudomonas phage PP7


A plant genus of the family Passifloraceae.


FMRF
FMRFamide, (D-Arg)-Isomer
FMRFamide, (D-Phe)-Isomer
FMRFamide, (D-Met)-Isomer
FMRF-amide
Phe-Met-Arg-Phe-NH2
Phe-Met-Arg-Phe-amide
FMRFamide, (D-phenylalanine)-Isomer
FMRFamide
FMRF-NH2

A molluscan neuroactive peptide which induces a fast excitatory depolarizing response due to direct activation of amiloride-sensitive SODIUM CHANNELS. (From Nature 1995; 378(6558): 730-3)


Rebound Nystagmus
Jerk Nystagmus
Rotational Nystagmus
Horizontal Nystagmus
Periodic Alternating Nystagmus
Vertical Nystagmus
Fatigable Positional Nystagmus
Symptomatic Nystagmus
Retraction Nystagmus
Rotary Nystagmus
Spontaneous Ocular Nystagmus
Non-Fatigable Positional Nystagmus
Unidirectional Nystagmus
Conjugate Nystagmus
Temporary Nystagmus
Multidirectional Nystagmus
Dissociated Nystagmus
See-Saw Nystagmus
Convergence Nystagmus
Nystagmus, Pathologic
Pendular Nystagmus
Permanent Nystagmus

Involuntary movements of the eye that are divided into two types, jerk and pendular. Jerk nystagmus has a slow phase in one direction followed by a corrective fast phase in the opposite direction, and is usually caused by central or peripheral vestibular dysfunction. Pendular nystagmus features oscillations that are of equal velocity in both directions and this condition is often associated with visual loss early in life. (Adams et al., Principles of Neurology, 6th ed, p272)


Cercopithecus ochraceus
Yellow Baboon
Central Yellow Baboon
Papio strepitus
Cynocephalus babouin
Choiropithecus rhodesiae
Papio cynocephalus cynocephalus
Papio cynocephalus

A species of baboon in the family CERCOPITHECIDAE found in southern equatorial and east Africa. They are smaller than PAPIO ANUBIS and have a thinner mane.


9-Aminoacridine
Aminopt
Aminacrine
Aminoacridine
Acridinamine
Mykocert
Aminacrine Hydrochloride
Aminoacridine Hydrochloride

A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.


Radioisotope Plaque Therapy
Implant Radiotherapy
Radioisotope Brachytherapy
Brachytherapy, Radioisotope
Radiotherapy, Interstitial
Radiotherapy, Intracavity
Interstitial Radiotherapy
Plaque Therapy, Radioisotope
Brachytherapy
Radiotherapy, Surface
Radiotherapy, Implant
Intracavity Radiotherapy
Curietherapy
Surface Radiotherapy

A collective term for interstitial, intracavity, and surface radiotherapy. It uses small sealed or partly-sealed sources that may be placed on or near the body surface or within a natural body cavity or implanted directly into the tissues.


Chromosomal Breaks
Chromosome Breaks
Chromosome Breakage
Chromosomal Breakage

A type of chromosomal aberration involving DNA BREAKS. Chromosome breakage can result in CHROMOSOMAL TRANSLOCATION; CHROMOSOME INVERSION; or SEQUENCE DELETION.


Contrast Echocardiography
Echocardiography, Cross-Sectional
Echocardiography, Two-Dimensional
Echocardiography, 2-D
Echocardiography
Echocardiography, M-Mode
Echocardiography, Transthoracic
Transthoracic Echocardiography
2D Echocardiography
Cross-Sectional Echocardiography
Two-Dimensional Echocardiography
Echocardiography, 2D
M-Mode Echocardiography
Echocardiography, Contrast
2-D Echocardiography

Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.


Paraplegia, Ataxic
Paraplegia, Flaccid
Paralysis, Legs
Paraplegia, Spastic
Paraplegia, Spinal
Paralysis, Lower Extremities
Paraplegia, Cerebral
Spastic Paraplegia
Paralysis, Lower Limbs
Paraplegia

Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.


Jejunal Cancer
Cancer of Jejunum
Cancer of the Jejunum
Jejunal Neoplasms
Cancer, Jejunal

Tumors or cancer in the JEJUNUM region of the small intestine (INTESTINE, SMALL).


Complete Argininosuccinic Acid Synthetase Deficiency Disease

Argininosuccinate Synthase Deficiency Disease

Partial Argininosuccinic Acid Synthetase Deficiency Disease

Deficiency Disease, Argininosuccinate Synthase

Argininosuccinic Acid Synthase Deficiency Disease

Deficiency, Argininosuccinic Acid Synthetase, Partial

Argininosuccinic Acid Synthetase Deficiency Disease, Partial

Argininosuccinic Acid Synthetase Deficiency, Complete

Deficiency Disease, Argininosuccinic Acid Synthase

Deficiency, Argininosuccinic Acid Synthetase, Complete

A group of diseases related to a deficiency of the enzyme ARGININOSUCCINATE SYNTHASE which causes an elevation of serum levels of CITRULLINE. In neonates, clinical manifestations include lethargy, hypotonia, and SEIZURES. Milder forms also occur. Childhood and adult forms may present with recurrent episodes of intermittent weakness, lethargy, ATAXIA, behavioral changes, and DYSARTHRIA. (From Menkes, Textbook of Child Neurology, 5th ed, p49)


R-14950
Flunarizin
Flunarizine
Flunarizine Dihydrochloride
Sibelium
Flunarizine Hydrochloride

Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.


Anetholetrithione
Trithioparamethoxyphenylpropene
Heporal
Anetholtrithione
Anisyldithiolthionine
Trithio
Sulfralem
Mucinol
Anethol Dithiolthione
Anethole Trithione
Sulfarlem
SL-25
Anetholtrithion
Tiotrifar
Felviten
Sialor
Trithioanethol
Sonicur

Choleretic used to allay dry mouth and constipation due to tranquilizers.


Clinically Isolated Syndrome, CNS Demyelinating

Clinically Isolated CNS Demyelinating Syndrome

The first region-restricted episode of CNS inflammatory demyelination in a patient. It is usually characterized by an acute monosymptomatic presentation of the optic nerves, brainstem, or spinal cord. It may not reoccur (isolated), or it may progress to MULTIPLE SCLEROSIS.


Circular Intronic RNA
Circular RNAs
circRNAs
ciRNA
Closed Circular RNA
circRNA
Circular RNA
RNA, Circular

RNA molecules in which the 3' and 5' ends are covalently joined to form a closed continuous loop. They are resistant to digestion by EXORIBONUCLEASES.


Diffusely Adherent Escherichia coli
Alkalescens-Dispar Group
Enteroinvasive Escherichia coli
Enteroinvasive E. coli
Enteroaggregative E. coli
Diffusely Adherent E. coli
E coli
EAggEC
Escherichia coli
Enteroaggregative Escherichia coli

A pathotype (virotype) of E. coli characterized by a distinct aggregative adherence pattern to HEp-2 cells.


Right Bundle Branch Block, ST Segment Elevation, and Sudden Death Syndrome

Sudden Unexplained Nocturnal Death Syndrome (SUNDS)

An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.


Cancer of Gastrointestinal Tract
Cancer of the Gastrointestinal Tract
Neoplasms, Gastrointestinal
Gastrointestinal Cancer
Gastrointestinal Neoplasms

Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.


Peptidase Inhibitory Proteins, Secretory

Proteinase Inhibitory Proteins, Secretory

Peptidase Inhibitory Peptides, Secretory

Proteinase Inhibitory Peptides, Secretory

Peptides and proteins found in BODILY SECRETIONS and BODY FLUIDS that are PROTEASE INHIBITORS. They play a role in INFLAMMATION, tissue repair and innate immunity (IMMUNITY, INNATE) by inhibiting endogenous proteinases such as those produced by LEUKOCYTES and exogenous proteases such as those produced by invading microorganisms.


Receptor-Like Protein Tyrosine Phosphatases, Class IV

Receptor-Like Protein Tyrosine Phosphatases, Class 4

Protein Tyrosine Phosphatase, Receptor Type A

Protein Tyrosine Phosphatase, Receptor Type E

A subclass of receptor-like protein tryosine phosphatases that contain short highly glycosylated extracellular domains and two active cytosolic protein tyrosine phosphatase domains.


Trapezoid Nuclear Complex
Preolivary Nucleus
Superior Olive
Superior Paraolivary Nucleus
Periolivary Nucleus
Superior Olivary Nuclei
Nucleus Olivaris Superior
Superior Olivary Complex

An auditory brainstem structure in the pontine tegmentum that contains several nuclei associated with auditory localization and is component of ascending and descending auditory pathways.


Fatty Liver with Encephalopathy
Reye's Syndrome
Reye-Johnson Syndrome
Reye Syndrome, Adult
Reye's-Like Syndrome
Reye's Syndrome, Adult
Reye-Like Syndrome
Reye Syndrome

A form of encephalopathy with fatty infiltration of the LIVER, characterized by brain EDEMA and VOMITING that may rapidly progress to SEIZURES; COMA; and DEATH. It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and CARNITINE metabolism.


Echo-Planar Magnetic Resonance Imaging
Echoplanar Magnetic Resonance Imaging
Magnetic Resonance Imaging, Echoplanar
Magnetic Resonance Imaging, Echo-Planar
Echoplanar MR Tomography
Echo-Planar Imaging
Echo-Planar MR Tomography
Echoplanar Imaging
MR Tomography, Echo-Planar
MR Tomography, Echoplanar

A type of MAGNETIC RESONANCE IMAGING that uses only one nuclear spin excitation per image and therefore can obtain images in a fraction of a second rather than the minutes required in traditional MRI techniques. It is used in a variety of medical and scientific applications.


Radon Daughters
Thoron Decay Products
Radon Decay Products
Radon Progeny
Thoron Progeny
Thoron Daughters
Radon Daughter Nuclides
Thoron Daughter Nuclides

Short-lived radioactive decay products of radon that include 216-Po, 214-Pb, 214-Bi, and 214-Po. They have an effective half-life of about 30 minutes and are solids that can deposit on the bronchial airways during inhalation and exhalation. This results in exposure of the respiratory airways to alpha radiation and can lead to diseases of the respiratory system, including lung cancer. (From Casarett and Doull's Toxicology, 4th ed, p740)


Telomere-Binding Proteins, Double Stranded

Double-Stranded Telomeric Binding Protein

Proteins that specifically bind to TELOMERES. Proteins in this class include those that perform functions such as telomere capping, telomere maintenance and telomere stabilization.


PL93-579
Privacy Act
PL 93-579
Privacy
Public Law 93-579

The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)


Killer Cell Lectin-Like Receptor Subfamily K, Member 1

NK Cell Lectin-Like Receptor Subfamily K, Member 1

An activating NK cell lectin-like receptor subfamily that regulates immune responses to INFECTION and NEOPLASMS. Members of this subfamily generally occur as homodimers.


Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities

Rare autosomal recessive syndrome, characterized by a milder set of clinical features with prolonged survival, compared to Donohue syndrome. Mutations in the same INSULIN RECEPTOR, mostly in the non-binding domain, result in Rabson-Mendenhall syndrome (allelic heterogeneity). Clinical features include insulin-resistant DIABETES MELLITUS, often with ACANTHOSIS NIGRICANS; DIABETIC KETOACIDOSIS; HYPERTRICHOSIS; and dysmorphisms.


Easterlin Hypothesis
Macroeconomic Factors
Capital
Cost of Living
Remittances
Microeconomic Factors
Factors, Economic
Consumption
Consumer Price Index
Policies, Economic
Utility Theory
Economic Policy
Economic Policies
Home Economics
Economics
Household Consumption
Economic Conditions
Economics, Home
Production
Policy, Economic
Economic Factors
Conditions, Economic

The science of utilization, distribution, and consumption of services and materials.


Visible Korean Human Project
American Visible Human Project
Visible Human Projects
United States Visible Human Project
Korean Visible Human Project
Visible Chinese Human Project
Chinese Visible Human Project

Digital image data sets, created by the NATIONAL LIBRARY OF MEDICINE, consisting of complete, anatomically detailed, three-dimensional representations of the normal male and female human bodies. The images were generated from carefully selected and prepared CADAVERS in three modes: computerized tomography (TOMOGRAPHY, X-RAY COMPUTED), magnetic resonance (MAGNETIC RESONANCE IMAGING) and cryosection (CRYOSECTIONING).


Nonketotic Hyperglycinemia, Type III
Hyperglycinemia, Nonketotic
Nonketotic Hyperglycinemia, Type I
Hyperglycinemia, Nonketotic, Type III
Non-ketotic Hyperglycinemia
Nonketotic Hyperglycinemia, Type II
Glycine Encephalopathy
Type III Nonketotic Hyperglycinemia
Type II Nonketotic Hyperglycinemia
Hyperglycinemia, Nonketotic, Type I
Nonketotic Hyperglycinemia
Hyperglycinemia, Nonketotic, Type II
Type I Nonketotic Hyperglycinemia

An autosomal recessive metabolic disorder caused by deficiencies in the mitochondrial GLYCINE cleavage system.


Peumus
Peumus boldus
Boldea fragrans
Boldo

A plant genus of the family MONIMIACEAE. Members contain boldine ALKALOIDS. Some PEUMUS species have been reclassified as CRYPTOCARYA.


Convulsant Effects
Convulsant Effect
Convulsants

Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were formerly used to stimulate respiration or as antidotes to barbiturate overdose. They are now most commonly used as experimental tools.


A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.


Myocardial Stunning
Hibernation, Myocardial
Stunned Myocardium
Myocardial Hibernation

Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity.


Congenital Cystic Adenomatoid Malformation, Type III

Lung Malformation, Cystic Adenomatoid, Congenital

Congenital Cystic Adenomatoid Malformation, Type 2

Congenital Cystic Adenomatoid Malformation, Type 1

Lung Malformation, Congenital Cystic Adenomatoid

Cystic Adenomatoid Malformation of Lung, Congenital

Congenital Cystic Adenomatoid Malformation, Type 3

Congenital Cystic Adenomatoid Malformation of Lung

This type is characterized by a bulky solid mass with cysts of <0.5 cm.


Carbamoyltransferases
Carbamoyl Transferases
Carboxyltransferases
Carboxyl and Carbamoyl Transferases
Carboxyl Transferases

A group of enzymes that catalyze the transfer of carboxyl- or carbamoyl- groups. EC 2.1.3.


Southern Blotting
Blot, Southern
Blotting, Southern
Southern Blot

A method (first developed by E.M. Southern) for detection of DNA that has been electrophoretically separated and immobilized by blotting on nitrocellulose or other type of paper or nylon membrane followed by hybridization with labeled NUCLEIC ACID PROBES.


Kayaking
Surfboarding
Boating
Wave Surfing
Water Skiing
Canoeing
Water Polo
Surfing, Wave
Water Sports
Rowing

Activities or games performed in a body of water.


Syndrome, Upper Airway Resistance, Sleep Apnea

Upper Airway Resistance Sleep Apnea Syndrome

A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)


Quinpirole Hydrochloride
Quinpirole Monohydrochloride
Quinpirole


Methoxa-Dome Puvalen Dermox Meloxine Ultramop Oxsoralen 8-Methoxypsoralen Ammoidin Geroxalen Xanthotoxin Méladinine 8-MOP Meladinina Oxsoralen-Ultra Meladinine Deltasoralen Methoxsalen

A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.


Antibody-Secreting Cells
Antibody-Producing Cells
Immunoglobulin-Secreting Cells
Immunoglobulin-Producing Cells

Cells of the lymphoid series that can react with antigen to produce specific cell products called antibodies. Various cell subpopulations, often B-lymphocytes, can be defined, based on the different classes of immunoglobulins that they synthesize.


Epulis, Congenital
Epulides, Congenital
Congenital Epulides
Neoplasms, Gingival
Congenital Epulis
Gingival Neoplasms

New abnormal growth of tissue in the GINGIVA.


Radiographic Phantom
Phantoms, Imaging
Radiographic Phantoms
Phantom, Radiographic
Phantom, Radiologic
Phantoms, Radiographic
Radiologic Phantom
Phantoms, Radiologic
Radiologic Phantoms

Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)


Psychologic Processes
Psychological Phenomena
Psychologic Processes and Principles
Psychological Processes

Mechanisms and underlying psychological principles of mental processes and their applications.


Consanguinity
Consanguineous Marriage
Inbreeding, Human
Consanguinous Mating

REPRODUCTION between genetically related individuals.


A plant genus of the family ARECACEAE. It is a tropical palm tree that yields a large, edible hard-shelled fruit from which oil and fiber are also obtained.


Lamina III
Lamina 4
Marginal Nucleus
Dorsal Horn
Lamina I
Lamina 3
Lamina 1
Clarke's Nucleus
Spinal Cord Posterior Horn
Posterior Horn of Spinal Cord
Clarke's Columns
Zona Spongiosa
Spinal Cord Dorsal Horn
Nucleus Dorsalis
Lamina IV

One of three central columns of the spinal cord. It is composed of GRAY MATTER spinal laminae I-VI.


A plant family of the order Urticales, subclass Hamamelidae, class Magnoliopsida. Members are trees and shrubs of temperate regions that have watery sap and alternate leaves which are lopsided at the base. The flowers lack petals.


Mother-Child Relations
Mother-Child Interaction
Mother-Infant Relations
Mother-Child Relationship
Mother-Infant Interaction


Glioma, Optic Nerve, Childhood
Malignant Optic Nerve Astrocytoma
Childhood Optic Nerve Glioma
Optic Glioma
Optic Nerve Glioma, Childhood
Glioma, Optic Nerve, Adult
Glioma, Optic Nerve
Optic Nerve Glioma
Adult Optic Nerve Glioma
Optic Nerve, Malignant Astrocytoma
Malignant Astrocytoma, Optic Nerve
Optic Nerve Glioma, Adult
Astrocytoma, Malignant, Optic Nerve

Glial cell derived tumors arising from the optic nerve, usually presenting in childhood.


Ganglioside Hydrolysis Activator Proteins

Ganglioside Degradation Activator Protein

A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as GLUCOSYLCERAMIDASE; GALACTOCEREBROSIDASE; BETA-N-ACETYLHEXOSAMINIDASE; and CEREBROSIDE-SULFATASE.


Egg White Proteins, Dietary
Yolk Proteins, Dietary
Egg Yolk Proteins, Dietary
Egg Proteins, Dietary
Dietary Egg Proteins

Proteins found in eggs which are consumed as a food.


Gingivosis
Epulides
Epulis
Gingival Diseases


Chondroitin Sulfate Lyase
Chondroitin AC Lyase
Chondroitin Eliminase
Chondroitin Lyases
Chondroitin B Lyase
Chondroitinase-AC II

Enzymes which catalyze the elimination of delta-4,5-D-glucuronate residues from polysaccharides containing 1,4-beta-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages thereby bringing about depolymerization. EC 4.2.2.4 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. EC 4.2.2.5 acts on chondroitin sulfate A and C.


Peritonitis, Chylous
Chyloperitoneum
Ascites, Chylous
Chylous Ascites
Chylous Peritonitis

Presence of milky lymph (CHYLE) in the PERITONEAL CAVITY, with or without infection.


Position Frequency Matrices
Position-Specific Scoring Matrix
Sequence Logo
Position-Specific Weight Matrices
Position Weight Matrix
Position-Specific Weight Matrix
Position-Specific Scoring Matrices
Sequence Logos
Position Weight Matrices

The tabular notation of the count per position of each potential residue as observed from an aligned set of sequences.


Biomimetic Materials
Biomimetic Devices
Biomimicry Materials
Biomimicry Devices

Devices fabricated with materials from biological systems.


Gardenal
Hysteps
Luminal
Phenobarbital Sodium
Phenobarbitone
Phenylethylbarbituric Acid
Phenemal
Phenobarbital
Phenobarbital, Monosodium Salt
Phenylbarbital

A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.


Dental Prosthesis, Surgical
Dental Implants
Prostheses, Surgical Dental
Surgical Dental Prosthesis
Prosthesis, Surgical Dental
Implant, Dental
Dental Implant
Dental Prostheses, Surgical
Implants, Dental
Surgical Dental Prostheses

Biocompatible materials placed into (endosseous) or onto (subperiosteal) the jawbone to support a crown, bridge, or artificial tooth, or to stabilize a diseased tooth.


Sex Organs, Accessory
Reproductive Organs
Accessory Sex Organs
Genitalia
Genital System
Genitals
Genital Organs
Reproductive System

The external and internal organs involved in the functions of REPRODUCTION.


Hypercholesterolemia, Autosomal Dominant, Type B

Apolipoprotein B-100, Familial Defective

Apolipoprotein B-100, Familial Ligand-Defective

Hypercholesterolemia that is caused by mutation in the LOW DENSITY LIPOPROTEIN RECEPTOR gene. This receptor defect prevents LDL binding to the cell membrane and uptake of cholesterol which normally suppresses further cholesterol synthesis.


Imipenem
Imipenem Anhydrous
MK-0787
Imipenem, Anhydrous
N-Formimidoylthienamycin
Imipemide
MK0787

Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.


Transmission Electron Microscopy
Microscopy, Electron Diffraction
Electron Microscopy, Transmission
Microscopy, Electron, Transmission
Electron Diffraction Microscopy

Electron microscopy in which the ELECTRONS or their reaction products that pass down through the specimen are imaged below the plane of the specimen.


Ovarian Cancer
Cancer of the Ovary
Cancer of Ovary
Ovary Neoplasms
Ovary Cancer
Ovarian Neoplasms
Neoplasms, Ovarian

Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.


Zone Therapy
Therapy, Zone
Massage
Massage Therapy

The systematic and methodical manipulations of body tissues best performed with the hands for the purpose of affecting the nervous and muscular systems and the general circulation.


Coxiella burnetii Vector-Borne Disease
Acute Q Fever
Coxiella burnetii Infection
Query Fever
Coxiella burnetii Fever
Chronic Q Fever
Q Fever

An acute infectious disease caused by COXIELLA BURNETII. It is characterized by a sudden onset of FEVER; HEADACHE; malaise; and weakness. In humans, it is commonly contracted by inhalation of infected dusts derived from infected domestic animals (ANIMALS, DOMESTIC).


Policy Analysis
Policy Development
Policy Making
Analysis, Policy

The decision process by which individuals, groups or institutions establish policies pertaining to plans, programs or procedures.


Leopard's Bane, False
Asteraceae
Carpesium
Heterotheca
Clibadium
Lychnophora
Sphaeranthus
Phagnalon
Doronicum
Compositae
Enhydra fluctuans
Ixeris
Viguiera
Aspilia
Silphium
Pseudognaphalium
Iostephane
Emilia Plant
Trixis

A plant genus. Members contain cadinane type SESQUITERPENES.


Taurolithocholate
Taurolithocholic Acid
Taurine Lithocholate
Lithocholyltaurine
Taurolithocholic Acid, Monosodium Salt

A bile salt formed in the liver from lithocholic acid conjugation with taurine, usually as the sodium salt. It solubilizes fats for absorption and is itself absorbed. It is a cholagogue and choleretic.


Artabotrys
Artabotrys uncinatus
Porcelia
Annonaceae
Fissistigma
Yingzhao

The source of the sesquiterpene PEROXIDES yingzhaosu A and yingzhaosu C.


Synthetic Peptide Synthesis
Peptide Synthesis, Synthetic
Methods of Inorganic Synthesis
Inorganic Synthesis Techniques
Chemistry Techniques, Synthetic
Organic Synthesis
Inorganic Synthesis
Organic Synthesis Techniques
Peptide Synthesis Methods
Inorganic Synthesis Methods
Methods of Organic Synthesis
Synthetic Chemistry Techniques
Methods of Peptide Synthesis
Peptide Synthesis Techniques
Organic Synthesis Methods

Methods used for the chemical synthesis of compounds. Included under this heading are laboratory methods used to synthesize a variety of chemicals and drugs.


RNA, Transfer, Met
Initiator tRNA
Transfer RNA, Met
RNA, Transfer, Initiator
tRNA(i)Met
tRNA(f)Met
tRNA(m)Met
tRNAMet
Methionine-Specific tRNAm
tRNA(Met)
Methionine-Specific tRNA

A transfer RNA which is specific for carrying methionine to sites on the ribosomes. During initiation of protein synthesis, tRNA(f)Met in prokaryotic cells and tRNA(i)Met in eukaryotic cells binds to the start codon (CODON, INITIATOR).


Emetine Hydrochloride
Emetine
Methylcephaeline
Ipecine
Emetine Dihydrochloride

The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.


Coagulation Factor VIII
Thromboplastinogen
Factor Eight
Factor VIII Coagulant Antigen
Factor VIII
Blood Coagulation Factor VIII
Factor 8
Factor VIIIC
Hyatt-C
Factor 8 C
Hyate-C
Factor VIII Clotting Antigen
F VIII-C
Factor VIII Procoagulant Activity

Factor VIII of blood coagulation. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.


Blalock-Taussig Procedure
Blalock Taussig Shunt
Blue Baby Operation
Blalock-Taussig Operation
Modified Blalock-Taussig Shunt
Modified Blalock-Taussig Procedure
Subclavian Pulmonary Artery Shunt

The use of a BLOOD VESSEL PROSTHESIS to connect the subclavian branch of the aorta to the pulmonary artery.


An injectable formulation of albumin-bound paclitaxel NANOPARTICLES.


Post-Vaccinal Encephalitis
Postvaccinal Encephalitis
Postinfectious Encephalomyelitis
Acute Disseminated Encephalomyelitis
Encephalitis, Postvaccinal
Encephalomyelitis, Postinfectious
Encephalitis, Vaccination
Disseminated Encephalomyelitis, Acute
Encephalomyelitis, Acute Disseminated
Post-Vaccinal Encephalomyelitis
Vaccination Encephalitis
Encephalomyelitis, Postexanthem
Postexanthem Encephalomyelitis
Encephalitis, Post-Vaccinal

An acute or subacute inflammatory process of the CENTRAL NERVOUS SYSTEM characterized histologically by multiple foci of perivascular demyelination. Symptom onset usually occurs several days after an acute viral infection or immunization, but it may coincide with the onset of infection or rarely no antecedent event can be identified. Clinical manifestations include CONFUSION, somnolence, FEVER, nuchal rigidity, and involuntary movements. The illness may progress to COMA and eventually be fatal. (Adams et al., Principles of Neurology, 6th ed, p921)


Clinical Trials, Randomized
Controlled Clinical Trials, Randomized
Randomized Controlled Trials as Topic
Trials, Randomized Clinical

Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.


Pirinitramide Dipidolor Dipydolor Piritramide Piritramid

A diphenylpropylamine with intense narcotic analgesic activity of long duration. It is a derivative of MEPERIDINE with similar activity and usage.


Primary Central Nervous System Neoplasms

Central Nervous System Neoplasms, Primary

Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.


Unnecessary Procedures
Surgery, Unnecessary
Unnecessary Surgery

Diagnostic, therapeutic, and investigative procedures prescribed and performed by health professionals, the results of which do not justify the benefits or hazards and costs to the patient.


Receptor, Estrogen Nuclear
Receptors, Estrogen, Type I
Estrogen Receptors Type II
Receptors, Estrogen, Type II
Estrogen Receptor Type II
Receptors, Estrogen
Estrogen Receptors
Estrogen Receptors Type I
Estrogen Nuclear Receptor
Estrogen Receptor Type I

Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.


Single Step-Parent
Parent, Single
Single Parent
Single Stepparent

A natural, adoptive, or substitute parent of a dependent child, who lives with only one parent. The single parent may live with or visit the child. The concept includes the never-married, as well as the divorced and widowed.


Vomiting, Postoperative
Postoperative Vomiting
Nausea and Vomiting, Postoperative
Postoperative Nausea
Postoperative Nausea and Vomiting
Nausea, Postoperative
PONV
Emesis, Postoperative
Postoperative Emesis

Emesis and queasiness occurring after anesthesia.


Infibulation
Clitoridectomy
Female Circumcision
Genital Mutilation, Female
Circumcision, Female
Clitorectomy

A general term encompassing three types of excision of the external female genitalia - Sunna, clitoridectomy, and infibulation. It is associated with severe health risks and has been declared illegal in many places, but continues to be widely practiced in a number of countries, particularly in Africa.


Medical Computer Science
Informatics, Clinical
Computer Science, Medical
Health Informatics
Medical Informatics
Informatics, Medical
Health Information Technology
Clinical Informatics
Medical Information Science
Information Science, Medical

Comprehensive, knowledge-based system capable of providing information to those who need it to make sound decisions about health.


Fibroid Tumor
Fibroid Uterus
Fibroid
Leiomyoma, Uterine
Fibroids, Uterine
Leiomyoma
Fibromyoma
Fibroma, Uterine

A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.


Antithrombic Drugs
Fibrinolytic Agents
Thrombolytic Drugs
Fibrinolytic Drugs
Antithrombotic Agents
Thrombolytic Agents

Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.


Intrathoracic Goiter
Goiter, Intrathoracic
Substernal Goiter
Goiter, Substernal

A goiter that grows behind the STERNUM and CLAVICLE.


Glucose Clamping
Glucose Clamp
Euglycaemic Clamping
Euglycaemic Clamp
Euglycemic Clamping
Euglycemic Clamp
Glucose Clamp Technique
Glucose Clamp Technic

Maintenance of a constant blood glucose level by perfusion or infusion with glucose or insulin. It is used for the study of metabolic rates (e.g., in glucose, lipid, amino acid metabolism) at constant glucose concentration.


A niacinamide and phenylurea derivative that inhibits multiple intracellular and cell surface kinases thought to be involved in ANGIOGENESIS, including RAF KINASES and VEGF RECEPTORS. It is used in the treatment of advanced RENAL CELL CARCINOMA and HEPATOCELLULAR CARCINOMA, and for treatment of THYROID CARCINOMA refractory to radioactive iodine therapy.


Voluntary Patient Safety Event Reporting

The process of minimizing risk to an organization by developing systems to identify and analyze potential hazards to prevent accidents, injuries, and other adverse occurrences, and by attempting to handle events and incidents which do occur in such a manner that their effect and cost are minimized. Effective risk management has its greatest benefits in application to insurance in order to avert or minimize financial liability. (From Slee & Slee: Health care terms, 2d ed)


Hypoxia-Inducible Factor Prolyl Hydroxylase 1

Hypoxia-Inducible Factor Prolyl Hydroxylase 3

Hypoxia-Inducible Factor Prolyl Hydroxylase 2

Dioxygenase enzymes that specifically hydroxylate a PROLINE residue on the HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. They are OXYGEN-dependent enzymes that play an important role in mediating cellular adaptive responses to HYPOXIA.


Electron Spectroscopy for Chemical Analysis

A form of photoelectron spectroscopy in which a sample is irradiated with a beam of ULTRAVIOLET RAYS and the energies of the resulting photoelectrons are analyzed.


Gene Modules
Gene Circuits
Gene Networks
Gene Module
Transcriptional Networks
Gene Regulatory Networks

Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.


Syngamiasis
Angiostrongylus Infections
Stephanurus dentatus Infections
Infections, Stephanurus dentatus
Infections, Strongylida
Strongylida Infections

Infections with nematodes of the order STRONGYLIDA.


Tocolytic Effects
Tocolytic Effect
Tocolytic Agents
Tocolytics

Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete.


Phosphoinositide-Specific Phospholipase C delta

A phosphoinositide phospholipase C subtype that is structurally defined by the presence of an N-terminal pleckstrin-homology and EF-hand domains, a central catalytic domain, and a C-terminal calcium-dependent membrane-binding domain.


Oxyquinoline Potassium Sulfate (2:1)
Oxine
Chinosol
Oxyquinoline Sulfate
Superol
Oxyquinol
Quinosol
8-Quinolinol
8-Oxyquinoline
Oxyquinoline
Khinozol
8-Hydroxyquinoline
Bioquin
Leioderm
8-Hydroxyquinoline Sulfate

An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.


Tetroses Aldotetroses Ketotetroses Ketotetrose Aldotetrose

Monosaccharide sugar molecules that contain a four carbon backbone.


Physalia
Portuguese Man-of-War
Hydrozoa
Hydrozoans
Physalia physalis
Liriope tetraphylla

A species of hydrozoan sea organism, not to be confused with LIRIOPE PLANT.


Solid-Phase Nucleotide Synthesis Techniques

Solid-Phase Peptide Synthesis Techniques

Techniques used to synthesize chemicals using molecular substrates that are bound to a solid surface. Typically a series of reactions are conducted on the bound substrate that results in either the covalent attachment of specific moieties or the modification of existing function groups. These techniques offer an advantage to those involving solution reactions in that the substrate compound does not have to be isolated and purified between the reaction steps.


Posterior Parahippocampal Gyrus
Hippocampal Gyri
Parahippocampal Gyrus
Uncus of Parahippocampal Gyrus
Parahippocampal Gyri
Gyrus Parahippocampalis
Posterior Parahippocampal Gyri
Presubiculum
Uncus, Parahippocampal Gyrus
Hippocampal Gyrus
Gyrus Hippocampi

A convolution on the inferior surface of each cerebral hemisphere, lying between the hippocampal and collateral sulci.


Anterograde Amnesia
Post-Ictal Memory Loss
Memory Loss, Anterograde
Amnesia, Post-Ictal
Amnesia, Anterograde

Loss of the ability to form new memories beyond a certain point in time. This condition may be organic or psychogenic in origin. Organically induced anterograde amnesia may follow CRANIOCEREBRAL TRAUMA; SEIZURES; ANOXIA; and other conditions which adversely affect neural structures associated with memory formation (e.g., the HIPPOCAMPUS; FORNIX (BRAIN); MAMMILLARY BODIES; and ANTERIOR THALAMIC NUCLEI). (From Memory 1997 Jan-Mar;5(1-2):49-71)


Mercazole
Thiamazol Hexal
Thimazol
Mercazol
Thiamazole
Mercazolyl
Tapazole
Mercasolyl
Merkazolil
1-Methyl-2-mercaptoimidazole
Methylmercaptoimidazole
Thyrozol
Methymazol
Strumazol
Methimazole
Thiamazol Henning
Tirodril
Favistan
Metisol
Methizol
Tiamazol
Metizol

A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.


Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of pregnant women but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5).


Spinal Cord
Conus Medullaris
Sacral Cord
Coccygeal Cord
Medulla Spinalis
Thoracic Cord
Myelon
Conus Terminalis
Lumbar Cord

A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.


Community Pharmacists
Clinical Pharmacists
Retail Pharmacists
Pharmacists

Pharmacists with clinical training to provide patient-centered evidence-based PHARMACEUTICAL CARE. Clinical pharmacists assist with the design, implementation, monitoring, and modification of the patient's drug treatment.


Human Endogenous Retroviruses
ERVs
HERVs
Retroviruses, Endogenous
Endogenous Retroviruses

Retroviruses that have integrated into the germline (PROVIRUSES) that have lost infectious capability but retained the capability to transpose.


Bandicota
Apodemus
Rats, Bandicoot
Praomys
Mastomys
Murinae
Acomys
Bandicoot Rats

A subfamily in the family MURIDAE, comprising the Old World MICE and RATS.


Water Snake
Lampropeltis
Garter Snake
King Snake
Colubridae
Thamnophis
Water Moccasin
Natrix

The largest family of snakes comprising five subfamilies: Colubrinae, Natricinae, Homalopsinae, Lycodontinae, and Xenodontinae. They show a great diversity of eating habits, from eating almost anything to having a specialized diet. They can be oviparous, ovoviviparous, or viviparous. The majority of North American snakes are colubrines. Among the colubrids are king snakes, water snakes, and garter snakes. Some genera are poisonous. (Goin, Goin, and Zug, Introduction to Herpetology, 3d ed, pp321-29)


Sperm Aspiration
Vasal Sperm Retrieval
Testicular Sperm Retrieval
Epididymal Sperm Retrieval
Testicular Sperm Aspiration
Sperm Retrieval
Epididymal Sperm Aspiration
Vasal Sperm Aspiration

Procedures to obtain viable sperm from the male reproductive tract, including the TESTES, the EPIDIDYMIS, or the VAS DEFERENS.


Cancer of the Bile Duct
Bile Duct Cancer
Cancer of Bile Duct
Bile Duct Neoplasms
Neoplasms, Bile Duct


Typus Degenerativus Amstelodamensis
Cornelia de Lange Syndrome 2
CdLS2
Cornelia de Lange Syndrome, X-Linked
Cornelia de Lange Syndrome 1
Cornelia de Lange Syndrome 3
Brachmann-De Lange Syndrome
De Lange's Syndrome
De Lange Syndrome
CdLS, X-Linked
Cornelia De Lange Syndrome

A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)


B Lymphocyte Heavy Chain Gene Rearrangement

B-Lymphocyte Heavy Chain Gene Rearrangement

Gene Rearrangement, B-Lymphocyte, Heavy Chain

B-Lymphocyte Mu Chain Gene Rearrangement

Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.


Cryoprotective Effects
Cryoprotective Effect
Cryoprotective Agents

Substances that provide protection against the harmful effects of freezing temperatures.


Garamycin
Gentacycol
Gentamicin Sulfate
G-Myticin
Gentamycins
Gentamicin
Genticin
Gentamicin Sulfate (USP)
Gentamycin
Gentavet
Gentamicins

A complex of closely related aminoglycoside bases (e.g., Gentamicins C1, C2, and C1(subA)), obtained from MICROMONOSPORA purpurea and related species.


Dynorphin A
Dynorphin (1-17)
Dynorphins
Dynorphin A (1-17)
Dynorphin

A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.


Nursing, Industrial
Nursing, Occupational Health
Occupational Health Nursing
Industrial Nursing

The practice of nursing in the work environment.


Hemeralopia
Vision Disability
Metamorphopsia
Day Blindness
Vision Disorders
Visual Disorders
Micropsia
Macropsia
Visual Impairment


Diagnostic aid in pancreas function determination.


A triazine derivative that introduces breaks into DNA strands in hypoxic cells, sensitizing tumor cells to the cytotoxic activity of other drugs and radiation.


Orthoreovirus
Nelson Bay orthoreovirus
Baboon orthoreovirus
Orthoreovirus, Nelson Bay
Orthoreovirus, Baboon

A species of ORTHOREOVIRUS isolated from baboons suffering from meningoencephalomyelitis.


Bovine Syncytial Virus
Spumavirinae
Macaque simian foamy virus
Bovine foamy virus
Spumaviruses
Spumavirus
Feline foamy virus
African green monkey simian foamy virus
Simian foamy virus 3
Simian foamy virus 1
Foamy Virus
Feline Syncytium-Forming Virus

Genus of non-oncogenic retroviruses which establish persistent infections in many animal species but are considered non-pathogenic. Its species have been isolated from primates (including humans), cattle, cats, hamsters, horses, and sea lions. Spumaviruses have a foamy or lace-like appearance and are often accompanied by syncytium formation. SIMIAN FOAMY VIRUS is the type species.


Suppurative Arthritis
Arthritis, Infectious
Bacterial Arthritides
Arthritis, Bacterial
Arthritis, Viral
Arthritides, Bacterial
Arthritis, Suppurative
Bacterial Arthritis
Arthritis, Septic
Infectious Arthritis

Arthritis caused by BACTERIA; RICKETTSIA; MYCOPLASMA; VIRUSES; FUNGI; or PARASITES.


Corticovirus
PM2 Bacteriophage
Bacteriophage PM2
Alteromonas phage PM2
Corticoviridae

The sole species in the genus Corticovirus, family CORTICOVIRIDAE.


Phospholipase C
Phospholipases, Type C
Lecithinase C
Type C Phospholipases
Phospholipases C

An enzyme found in the alpha-toxin of Clostridium welchii and other strains of clostridia and bacilli. It hydrolyzes glycerophosphatidates with the formation of 1,2-diacylglycerol and a phosphorylated nitrogenous base such as choline.


Dobutamine Stress Echocardiography
Echocardiography, Stress, Dobutamine
Echocardiography, Stress
Stress Echocardiography

A method of recording heart motion and internal structures by combining ultrasonic imaging with exercise testing (EXERCISE TEST) or pharmacologic stress.


Japanese Quail
Coturnix japonica
Coturnix

A genus of BIRDS in the family Phasianidae, order GALLIFORMES, containing the common European and other Old World QUAIL.


Neoplasms, Tonsillar
Tonsillar Neoplasms
Cancer of Tonsil
Tonsil Cancer
Tonsillar Cancer
Cancer of the Tonsil
Neoplasms, Tonsil
Tonsil Neoplasms

Tumors or cancer of the PALATINE TONSIL.


Diphenoxylate Hydrochloride
Diphenoxylate Monohydrochloride
Diphenoxylate

A MEPERIDINE congener used as an antidiarrheal, usually in combination with ATROPINE. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity.


Cancer, Radiation-Induced
Radiation-Induced Neoplasms
Radiation-Induced Cancer
Neoplasms, Radiation-Induced

Tumors, cancer or other neoplasms produced by exposure to ionizing or non-ionizing radiation.


Cystatin-2
Salivary Gland Acidic Protein
Cystatin S, Salivary Gland
Salivary Cystatins
SD-Type Cystatins
Cystatin SA
Cystatin S
Cystatin-S5
Cystatin-SN
Cystatin-SA-I
Salivary Acidic Protein 1
Cystatin-4
Cystatin SA2
Acid Protein (Submandibular Gland)
Cystatin-1

A group of closely-related cystatins found in SALIVA.


A ZINC metalloenzyme that catalyzes the transfer of a methyl group from BETAINE to HOMOCYSTEINE to produce dimethylglycine and METHIONINE, respectively. This enzyme is a member of a family of ZINC-dependent METHYLTRANSFERASES that use THIOLS or selenols as methyl acceptors.


Phantom Limb
Phantom Sensation
Pseudomelia
Phantom Limb Pain
Phantom Pain

Perception of painful and nonpainful phantom sensations that occur following the complete or partial loss of a limb. The majority of individuals with an amputated extremity will experience the impression that the limb is still present, and in many cases, painful. (From Neurol Clin 1998 Nov;16(4):919-36; Brain 1998 Sep;121(Pt 9):1603-30)


Zenapax
Dacliximab
Ro 24-7375
Zinbryta
Daclizumab
Ro-24-7375

An anti-TAC (INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT) humanized monoclonal antibody (immunoglobulin G1 disulfide with human-mouse monoclonal clone 1H4 light chain, dimer) that is used in the treatment of ACUTE RELAPSING MULTIPLE SCLEROSIS.


Resistance Training
Weight-Lifting Strengthening Program
Strength Training
Weight-Bearing Exercise Program
Weight-Lifting Exercise Program
Weight-Bearing Strengthening Program

A type of strength-building exercise program that requires the body muscle to exert a force against some form of resistance, such as weight, stretch bands, water, or immovable objects. Resistance exercise is a combination of static and dynamic contractions involving shortening and lengthening of skeletal muscles.


Excess Mortality
Mortality Rate
Determinants, Mortality
Mortality Determinants
Differential Mortality
Age Specific Death Rate
Age-Specific Death Rate
Mortality
Death Rate
Mortality, Excess
Case Fatality Rate
Mortality, Differential
Mortality Decline
Decline, Mortality

All deaths reported in a given population.


Zinc Acetate Dihydrate
Zinc Acetate Anhydrous
Anhydrous Zinc Acetate
Galzin
Zinc Acetate

A salt produced by the reaction of zinc oxide with acetic acid and used as an astringent, styptic, and emetic.


Catharanthus
Periwinkle, Madagascar
Vinca rosea
Catharanthus roseus

A plant genus of the family Apocynaceae. It is the source of VINCA ALKALOIDS, used in leukemia chemotherapy.


Multi-Ingredient Cold, Flu, and Allergy Medications

Multi-Ingredient Cold and Flu Medications

Cold, Flu, and Allergy Medications, Multi-Ingredient

Cold and Flu Medications, Multi-Ingredient

A broad category of multi-ingredient preparations that are marketed for the relief of upper respiratory symptoms resulting from the COMMON COLD; ALLERGIES; or HUMAN INFLUENZA. While the majority of these medications are available as OVER-THE-COUNTER DRUGS some of them contain ingredients that require them to be sold as PRESCRIPTION DRUGS or as BEHIND-THE COUNTER DRUGS.


Accessory Basal Amygdaloid Nucleus
Basolateral Amygdala
Deep Nuclei, Amygdaloid
Basolateral Amygaloid Nucleus
Amygdaloid Basolateral Complex
Basolateral Nuclear Group
Lateral Principal Nucleus of Amygdala
Deep Nuclei, Amygdala
Paralaminar Nucleus
Basal Nucleus of the Amygdala
Basolateral Nuclear Complex
Accessory Basal Nucleus
Lateral Amygdaloid Nucleus
Basal Amygdaloid Nucleus
Lateral Nucleus of Amygdala

A set of amygdalar nuclei bordered laterally by the EXTERNAL CAPSULE and medially by the CENTRAL AMYGDALOID NUCLEUS.


Quadriplegia
Spastic Quadriplegia
Spastic Tetraplegia
Quadriparesis
Paralysis, Spinal, Quadriplegic
Flaccid Tetraplegia
Tetraplegia
Flaccid Quadriplegia

Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.


The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.


Feeding Patterns
Dietary Habits
Food Habits
Diet Habits
Eating Habits
Feeding Behavior
Eating Behavior


Idiopathic Inflammatory Myopathies
Inflammatory Myopathies, Idiopathic
Myositis, Infectious
Idiopathic Inflammatory Myopathy
Myopathies, Idiopathic Inflammatory
Inflammatory Myopathy, Idiopathic
Inflammatory Muscle Diseases
Muscle Diseases, Inflammatory
Inflammatory Myopathy
Myopathy, Inflammatory
Myositis
Myositis, Focal
Myositis, Proliferative
Infectious Myositis
Idiopathic Inflammatory Myositis

Inflammation of a muscle or muscle tissue.


Myotonic Dystrophy 1
Congenital Myotonic Dystrophy
Dystrophia Myotonica 1
Steinert Disease
Proximal Myotonic Myopathy
Myotonia Atrophica
Ricker Syndrome
Myotonic Dystrophy, Congenital
Myotonic Myopathy, Proximal
Myotonia Dystrophica
PROMM (Proximal Myotonic Myopathy)
Steinert's Disease
Dystrophia Myotonica 2
Dystrophia Myotonica
Steinert Myotonic Dystrophy
Myotonic Dystrophy 2
Myotonic Dystrophy

Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.


Radiosurgery, Stereotactic
Linear Accelerator Radiosurgery
Stereotactic Radiosurgery
Stereotactic Radiation
Radiosurgery, Gamma Knife
Radiosurgery, Linear Accelerator
LINAC Radiosurgery
Gamma Knife Radiosurgery
CyberKnife Radiosurgery
Radiosurgery
Stereotactic Radiation Therapy
Stereotactic Body Radiotherapy

A type of radiosurgery performed with a LINAC radiosurgery system mounted on a robotic manipulator.


Estrogens, Synthetic
Estradiol Congeners
Synthetic Estrogens
Estrogen Analogs
Estrogen Analogues

Compounds obtained by chemical synthesis which possess estrogenic activity, but differ in structure from naturally occurring estrogens.


Viral Fusion-GP
F Protein (Sendai Virus)
F Protein SV
Virus Fusion Proteins
Glycoprotein, Viral Fusion
Viral Fusion Proteins
Viral Fusion Glycoproteins
Mumps Virus Fusion Protein
Sendai Virus Fusion Protein
Paramyxovirus Fusion Protein
F-Glycoprotein SV
F1 Polypeptide (Paramyxovirus)
Fusion Glycoprotein, Viral
Fusion VP1 Protein
F Protein Newcastle Disease Virus
Fusion Proteins, Viral
Measles Fusion Protein
F Protein Measles Virus

Proteins, usually glycoproteins, found in the viral envelopes of a variety of viruses. They promote cell membrane fusion and thereby may function in the uptake of the virus by cells.


Epinephrine Hydrochloride, Racemic Mixture

Adrenaline Hydrochloride, Racemic Mixture

A racemic mixture of d-epinephrine and l-epinephrine.


Colonic Pseudo-Obstruction
Ogilvie Disease
Ogilvie's Syndrome
Pseudoobstruction, Colonic
Ogilvie Syndrome
Pseudo-Obstruction, Colonic

Functional obstruction of the COLON leading to MEGACOLON in the absence of obvious COLONIC DISEASES or mechanical obstruction. When this condition is acquired, acute, and coexisting with another medical condition (trauma, surgery, serious injuries or illness, or medication), it is called Ogilvie's syndrome.


Genetic Counseling, Prenatal
Genetic Counseling
Prenatal Genetic Counseling
Counseling, Genetic

An educational process that provides information and advice to individuals or families about a genetic condition that may affect them. The purpose is to help individuals make informed decisions about marriage, reproduction, and other health management issues based on information about the genetic disease, the available diagnostic tests, and management programs. Psychosocial support is usually offered.


Cerebral Amyloid Angiopathy, Cst3-Related

Cerebral Hemorrhage, Hereditary, With Amyloidosis

Hereditary Cerebral Hemorrhage With Amyloidosis

Hereditary Cerebral Amyloid Angiopathy, Icelandic Type

Icelandic Type Hereditary Cerebral Amyloid Angiopathy

Autosomal Dominant Cerebrovascular Amyloidosis

Amyloidosis, Cerebroarterial, Icelandic Type

A familial disorder marked by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES.


Clustered Regularly Interspaced Short Palindromic Repeats

Short pieces of unique sequence in between CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS. These spacers, which are homologous to previously invading viruses, are generated from invading viral DNA and are inserted in between the repeats.


Meningeal Cancer
Neoplasms, Leptomeningeal
Meningeal Neoplasms, Benign
Meningeal Neoplasms, Malignant
Malignant Meningeal Neoplasms
Neoplasms, Meningeal
Meningeal Tumors
Benign Meningeal Neoplasms
Meningeal Neoplasms
Meningeal Neoplasms, Intracranial
Spinal Meningeal Neoplasms
Leptomeningeal Neoplasms
Intracranial Meningeal Neoplasms

Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.


4306-CB
Dipotassium Chlorazepate
Tranxene
Clorazepate
Tranxilium
Chlorazepate
Clorazepate Monopotassium
Clorazepic Acid
Clorazepate Dipotassium

A water-soluble benzodiazepine derivative effective in the treatment of anxiety. It has also muscle relaxant and anticonvulsant actions.


Return to Recreational Activities
Resumption of Sporting Activity
Resumption of Recreational Activities
Return to Sport
Return to Play
Return to Sporting Activities

Resumption of sporting activity following a hiatus or period of absence due to injury or other reasons.


Extranodal Extension
Extracapsular Extension
Tumor Deposit
Extranodal Tumor Deposits

Tumor nodules located in the mesorectal/pericolic fatty tissues of the primary tumor.


Germ Cells, Plant
Generative Cells, Plant
Plant Germ Cells
Gametophytes
Plant Gametes
Gametes, Plant

The forms of the PLANT GERM CELLS at the final stage of GAMETOGENESIS.


Colesevelam
Welchol
CholestaGel
Colesevelam HCl
GT-31104
GT 31104
GT31-104
Colesevelam Hydrochloride

An allylamine derivative that binds BILE ACIDS in the intestine and is used as an ANTICHOLESTEREMIC AGENT in the treatment of HYPERCHOLESTEROLEMIA and HYPERLIPIDEMIAS.


Artemether, Lumefantrine Drug Combination

Artemether, Benflumetol Drug Combination

Drug combination of artemether and lumefantrine that is used to treat PLASMODIUM FALCIPARUM MALARIA.


RNA, Messenger, Polyadenylated
RNA, Polyadenylated
Poly(A) RNA
Messenger RNA, Polyadenylated
Poly(A) Tail
mRNA, Non-Polyadenylated
mRNA
mRNA, Polyadenylated
RNA, Messenger
Messenger RNA
Polyadenylated mRNA
Poly(A)+ mRNA
Non-Polyadenylated mRNA
Poly(A)+ RNA

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.


Psychogenic Inversion of Circadian Rhythm

Inversion of Circadian Rhythm, Psychogenic

Disruptions of the rhythmic cycle of bodily functions or activities.


Educational Measurement
Educational Assessment
Assessment, Educational
Graduate Records Examination
Measurement, Educational
Examination, Graduate Records

The assessing of academic or educational achievement. It includes all aspects of testing and test construction.


Animal Mammary Carcinoma
Mammary Neoplasms, Animal
Mammary Carcinoma, Animal
Neoplasms, Mammary
Mammary Neoplasms

Tumors or cancer of the MAMMARY GLAND in animals (MAMMARY GLANDS, ANIMAL).


Staff Workload
Work Load
Workload
Employee Work Load
Employee Workload
Staff Work Load

The total amount of work to be performed by an individual, a department, or other group of workers in a period of time.


Alfacid LM-427 Rifabutine Ansatipine Ansatipin Mycobutin Rifabutin Ansamycin

A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.


Seizure Disorder, Nonconvulsive Generalized

Seizure Disorder, Generalized, Convulsive

Generalized Seizure Disorder, Convulsive

Generalized Nonconvulsive Seizure Disorder

Nonconvulsive Seizure Disorder, Generalized

Convulsive Seizure Disorder, Generalized

Generalized Seizure Disorder, Nonconvulsive

Seizure Disorder, Convulsive, Generalized

Seizure Disorder, Generalized Nonconvulsive

Nonconvulsive Generalized Seizure Disorder

Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71(4):405-14)


Total Quality Management
Six Sigma
Lean Six Sigma
Continuous Quality Management
Sigma Metrics

A set of techniques and metric tools used to strive for a near perfect process or production. It targets a defect rate of 3.4 per million or 6 standard deviations (designated as Greek letter sigma).


A synthetic rifamycin derivative and anti-bacterial agent that is used for the treatment of GASTROENTERITIS caused by ESCHERICHIA COLI INFECTIONS. It may also be used in the treatment of HEPATIC ENCEPHALOPATHY.


Capillariasis
Infections, Dioctophyma renale
Capillaria hepatica Infection
Capillaria philippinensis Infection
Enoplida Infections
Capillaria Infections
Dioctophyma renale Infections
Hepatic Capillariasis
Infections, Enoplida
Intestinal Capillariasis

Infections with nematodes of the order ENOPLIDA.


Antiangiogenesis Effects
Inhibitors, Angiogenetic
Angiogenetic Antagonists
Anti-Angiogenesis Effect
Antiangiogenesis Effect
Angiostatic Agents
Anti-Angiogenic Drugs
Angiogenic Inhibitors
Inhibitors, Angiogenesis
Antiangiogenic Agents
Angiogenetic Inhibitors
Anti-Angiogenesis Effects
Inhibitors, Neovascularization
Anti-Angiogenetic Agents
Antagonists, Angiogenic
Angiogenesis Factor Inhibitors
Angiogenesis Inhibitors
Angiogenic Antagonists
Inhibitors, Angiogenic
Neovascularization Inhibitors

Agents and endogenous substances that antagonize or inhibit the development of new blood vessels.


Departments, Hospital Radiology
Department, X-Ray
X-Ray Department
Radiology Departments, Hospital
X-Ray Departments
Departments, X-Ray
Department, Hospital Radiology
Radiology Department, Hospital
Hospital Radiology Department

Hospital department which is responsible for the administration and provision of x-ray diagnostic and therapeutic services.


Acantholytic Dyskeratotic Epidermal Nevi

Acantholytic Dyskeratotic Epidermal Nevus

An alleleic variant of Darier's disease.


Cotoneaster
Amelanchier
Serviceberry
Cercocarpus
Rosaceae
Chaenomeles
Quince
Dryas Plant
Quince, Flowering
Cydonia
Mahogany, Mountain
Coleogyne
Mountain Mahogany

A plant genus of the family ROSACEAE. Do not confuse with Dryas Butterfly (BUTTERFLIES).


Amplification Technics, Nucleic Acid
RNA Amplification Technics
Nucleic Acid Amplification Tests
Amplification Techniques, Nucleic Acid
Techniques, Nucleic Acid Amplification
Nucleic Acid Amplification Techniques
DNA Amplification Techniques
DNA Amplification Technics
Nucleic Acid Amplification Technics
Technics, Nucleic Acid Amplification
RNA Amplification Techniques
Nucleic Acid Amplification Test

Diagnostic nucleic acid amplification procedures used to test for the presence of an infectious agent or a specific ALLELE or MUTATION.


Thrombin Receptor Activating Peptide Ligand

A cryptic peptide ligand contained within the N-terminal of the thrombin receptor.


Human parainfluenza virus 1
Parainfluenza Virus Type 1
Parainfluenza Virus 1, Human
Hemadsorption Virus 2
Para-Influenza Virus Type 1

A species of RESPIROVIRUS also called hemadsorption virus 2 (HA2), which causes laryngotracheitis in humans, especially children.


Ecteinascidin 743
ET 743
ET-743
Trabectedin
NSC 684766
Yondelis

A complex structure that includes isoquinolines joined by a cyclic ester; it is a DNA-binding agent and guanine N2 alkylator derived from the marine tunicate, Ecteinascidia turbinata. Trabectedin is used for the treatment of advanced soft-tissue SARCOMA, after failure of ANTHRACYCLINES or IFOSFAMIDE drug therapy.


Medicine, Atomic
Radiology, Nuclear
Nuclear Medicine
Atomic Medicine
Medicine, Nuclear
Nuclear Radiology

A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds.


Type III Sodium-Phosphate Symporter Proteins

Pit1 Sodium-Dependent Phosphate Symporter

Solute Carrier Family 20 (Phosphate Transporter), Member 2

Type III Sodium-Phosphate Cotransporter Proteins

Type III Na-Dependent Phosphate Cotransporter

Amphotropic Murine Leukemia Virus Receptor

Sodium-Phosphate Cotransporter Proteins, Type III

Pit2 Sodium-Dependent Phosphate Symporter

Solute Carrier Family 20 (Phosphate Transporter), Member 1

A family of highly conserved and widely expressed sodium-phosphate cotransporter proteins. They are electrogenic sodium-dependent transporters of phosphate that were originally identified as retroviral receptors in HUMANS and have been described in yeast and many other organisms.


Behavior Test
Behavioral Test
Behavioral Rating Scale
Behavior Rating Scale

Written, visual, or verbal evaluation administered to assess the cognitive and emotional functioning of both humans and animals.


Aminohexanoates
Aminohexanoic Acid Derivatives
Aminocaproates
Aminocaproic Acids
Aminohexanoic Acids
Aminocaproic Acid Derivatives

Amino derivatives of caproic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the amino caproic acid structure.


Caimans
Caymans
Crocodiles
Alligators
Alligators and Crocodiles

Large, long-tailed reptiles, including caimans, of the order Loricata.


Blindness, Unilateral
Blindness
Bilateral Blindness
Blindness, Bilateral
Blindness Transient
Blindness, Hysterical
Unilateral Blindness
Blindness, Legal
Sudden Visual Loss
Blindness Bilateral
Visual Loss Sudden
Blindness, Monocular
Blindness, Complete
Amaurosis
Blindness Unilateral
Blindness, Transient
Blindness, Acquired

The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.


Hypertranscription, X-Chromosome
Gene Dosage Compensation
X-Chromosome Hypertranscription
Dosage Compensation (Genetics)
Dosage Compensation, Genetic

Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female.


Urinals
Toilets
Commodes
Bathroom Equipment
Bedpans

Receptacles used for collection of human excrement.


Myasthenia Gravis, Autoimmune Experimental

Myasthenia Gravis, Experimental Autoimmune

Experimental Autoimmune Myasthenia Gravis, Passive Transfer

Autoimmune Experimental Myasthenia Gravis

Myasthenia Gravis, Autoimmune, Experimental

Passive Transfer Experimental Autoimmune Myasthenia Gravis

Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)


Vaginal Examinations
Pelvic Examination
Pelvic Exam
Gynecological Exam
Gynecological Examination
Vaginal Exam

External and internal inspection of the FEMALE GENITALIA. (from Dictionary of Obstetrics and Gynecology)


Toronja
Grapefruit
Citrus x paradisi
Citrus paradisi

A plant species of the genus CITRUS, family RUTACEAE that produces the familiar grapefruit. There is evidence that grapefruit inhibits CYTOCHROME P-450 CYP3A4, resulting in delayed metabolism and higher blood levels of a variety of drugs.


Indolesulfonic acid used as a dye in renal function testing for the detection of nitrates and chlorates, and in the testing of milk.


A plant genus of the family ASTERACEAE. Members contain ATRACTYLOSIDE.


Franklin's Disease
mu-Chain Disease
Heavy Chain Disease
gamma-Chain Disease
Franklin Disease

A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes.


Intergenic Sequence
DNA, Spacer
Intercistronic Region
Sequence, Intergenic
DNA, Junk
Intergenic Region
Junk DNA
DNA, Intergenic
Intercistronic Sequence
Spacer DNA
Intergenic DNA

Any of the DNA in between gene-coding DNA, including untranslated regions, 5' and 3' flanking regions, INTRONS, non-functional pseudogenes, and non-functional repetitive sequences. This DNA may or may not encode regulatory functions.


LDL Cholesteryl Linoleate
Cholesteryl Linoleate, LDL
LDL Cholesterol
beta-Lipoprotein Cholesterol
Cholesterol, LDL
Low Density Lipoprotein Cholesterol

Cholesterol which is contained in or bound to low density lipoproteins (LDL), including CHOLESTEROL ESTERS and free cholesterol.


Arterial Tension
Aortic Tension
Aortic Pressure
Arterial Blood Pressure
Blood Pressure, Arterial
Arterial Pressure
Aortic Pulse Pressure
Aortic Blood Pressure
Mean Aortic Pressure
Blood Pressure, Aortic
Mean Arterial Pressure


Hepatitis, Fulminant
Drug-induced Hepatic Necrosis
Submassive Hepatic Necrosis
Fulminant Hepatitis
Acute Yellow Atrophy of Liver
Acute Yellow Atrophy
Massive Hepatic Necrosis

Extensive and rapid death of parenchymal cells in the LIVER, often due to exposure to toxic materials or drug-induced injury. It is characterized by a soft, flabby, yellow-brown wrinkled, and shrunken liver. It was called "acute yellow atrophy".


Abrus
Precatory Bean Plant
Abrus precatorius
Bean Plant, Precatory

A plant genus of the family FABACEAE whose members contain the highly toxic compound ABRIN.


Eremophila alpestris
Songbirds
Thrushes
Robins
Horned Lark
Oscines
Flycatchers
Turdidae
Warblers
Troglodytidae
Troglodytinae
Wrens

PASSERIFORMES of the suborder, Oscines, in which the flexor tendons of the toes are separate, and the lower syrinx has 4 to 9 pairs of tensor muscles inserted at both ends of the tracheal half rings. They include many commonly recognized birds such as CROWS; FINCHES; robins; SPARROWS; and SWALLOWS.


Employee Assistance Programs (Health Care)

Health services for employees, usually provided by the employer at the place of work.


Waardenburg Syndrome with Upper Limb Anomalies

Waardenburg Syndrome with Dystopia Canthorum

White Forelock (Poliosis) Syndrome with Multiple Congenital Malformations

Rare, autosomal dominant disease with variable penetrance and several known clinical types. Characteristics may include depigmentation of the hair and skin, congenital deafness, heterochromia iridis, medial eyebrow hyperplasia, hypertrophy of the nasal root, and especially dystopia canthorum. The underlying cause may be defective development of the neural crest (neurocristopathy). Waardenburg's syndrome may be closely related to piebaldism. Klein-Waardenburg Syndrome refers to a disorder that also includes upper limb abnormalities.


Nucleus Lentiformis
Lentiform Nuclei
Corpus Striatum
Lenticular Nucleus
Lentiform Nucleus

Striped GRAY MATTER and WHITE MATTER consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the THALAMUS in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The WHITE MATTER is the INTERNAL CAPSULE.


Tetradium ruticarpum
Euodia
Evodiae Fructus
Evodia
Evodia rutaecarpa
Wu Zhu Yu
Euodia ruticarpa

Dried ripe fruit of Evodia ruticarpa that is used in DRUGS, CHINESE HERBAL.


G-Protein-Coupled Receptor Kinase 4delta

G-Protein-Coupled Receptor Kinase 4alpha

G-Protein-Coupled Receptor Kinase 4gamma

A G-protein-coupled receptor kinase subtype that is primarily expressed in the TESTES and BRAIN. Variants of this subtype exist due to multiple alternative splicing of its mRNA.


Squatters
Transients
Transients and Migrants
Migrants
Nomads
Migrant Workers
Nonmigrants

People who frequently change their place of residence.


A histamine H2 receptor antagonist that is used as an anti-ulcer agent.


Plantago arenaria
Plantago
Plantago indica
Plantago psyllium
Plantain
Narrow-Leaved Plantain
Plantago ovata
Plantago lanceolata
English Plantain

A plant genus of the family Plantaginaceae. The small plants usually have a dense tuft of basal leaves and long, leafless stalks bearing a terminal spike of small flowers. The seeds, known as PSYLLIUM, swell in water and are used as laxatives. The leaves have been used medicinally.


Ro-13-7652
Acitretin, (Z,E,E,E)-Isomer
Isoacitretin
Isoetretin
13-cis-Acitretin
Ro 13-7652
Etretin
Neotigason
Ro 10-1670
Ro-10-1670
Soriatane
Acitretin

An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of ETRETINATE with the advantage of a much shorter half-life when compared with etretinate.


NADH-Cytochrome B5 Reductase
NADH-Ferrihemoglobin Reductase
NADH Methemoglobin Reductase
Cytochrome-B(5) Reductase
Methemoglobin Reductase
NADH Cytochrome B5 Reductase

The soluble, erythrocyte form of cytochrome-B(5) reductase. It catalyzes the reduction of methemoglobin (ferrihemoglobin) to hemoglobin (ferrohemoglobin).


Hereditary Progressive Chorea Without Dementia

Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.


Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins

A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins

A subfamily of ADAMTS proteins that lack a protease domain.


Medical History, 20th Cent.
Medicine, 20th Cent.
20th Cent. History (Medicine)
History of Medicine, 20th Cent.
20th Century History
20th Cent. History of Medicine
Historical Events, 20th Century
History, 20th Century
History, Twentieth Century
20th Cent. Medicine

Events of lasting impact or importance occurring in the 20th century.


Sodium Dependent Neutral Amino Acid Transport Proteins

Sodium Independent Neutral Amino Acid Transporters

Zwitterionic Amino Acid Transport Systems

Zwitterionic Amino Acid Transport Proteins

Sodium Dependent Neutral Amino Acid Transporters

Na+-Independent Neutral Amino Acid Transporter

Sodium Independent Neutral Amino Acid Transport Proteins

Amino acid transporter systems capable of transporting neutral amino acids (AMINO ACIDS, NEUTRAL).


Arts, Industrial
Industrial Arts
Technology

The application of scientific knowledge to practical purposes in any field. It includes methods, techniques, and instrumentation.


Major Depressive Disorder
Psychosis, Involutional
Depressive Disorder, Major
Melancholia, Involutional
Paraphrenia, Involutional
Depression, Involutional

Form of depression in those MIDDLE AGE with feelings of ANXIETY.


Receptors, Extracellular Matrix Glycoprotein

Extracellular Matrix Glycoprotein Receptors

A group of INTEGRINS that includes the platelet outer membrane glycoprotein GPIIb-IIIa (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX) and the vitronectin receptor (RECEPTORS, VITRONECTIN). They play a major role in cell adhesion and serve as receptors for fibronectin, von Willebrand factor, and vitronectin.


Polyposis, Skin Pigmentation, Alopecia, And Fingernail Changes

A nonfamilial polyposis syndrome that is characterized by the presence of diffuse gastrointestinal polyposis, DIARRHEA, and PROTEIN-LOSING ENTEROPATHY. It was first reported by Cronkhite and Canada in 1955.


Cytotoxin-Like Basic Protein (Cobra Venom)

Most abundant proteins in COBRA venom; basic polypeptides of 57 to 62 amino acids with four disulfide bonds and a molecular weight of less than 7000; causes skeletal and cardiac muscle contraction, interferes with neuromuscular and ganglionic transmission, depolarizes nerve, muscle and blood cell membranes, thus causing hemolysis.


Fosinopril, (1(S*(R*)),2 alpha,4 alpha)-(D-Pro)-Isomer

Fosinopril, (1(S*(S*)),2 alpha,4 beta)-Isomer

Fosinopril, (1(S*(R*)),2 alpha,4 beta)-Isomer

A phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.


Memory and Learning Tests
California Verbal Learning Test
Rey Auditory Verbal Learning Test
TOMAL
Rivermead Behavioural Memory Test
Test of Memory Malingering
Test of Memory and Learning

Tests designed to evaluate general and specific areas of behaviors and abilities associated with memory and/or learning.


Validity of Results
Reliability of Results
Reproducibility of Findings
Validity (Epidemiology)
Reproducibility of Results
Reliability (Epidemiology)
Face Validity
Test-Retest Reliability
Reliability and Validity

Consistency of measurements in a test/procedure/assessment that is repeated over time.


Maternal-Child Nursing
Maternity Nursing
Nursing, Maternity
Nursing, Maternal-Child

The nursing specialty that deals with the care of women throughout their pregnancy and childbirth and the care of their newborn children.


9 alpha-Fluorohydrocortisone
9-Fluorocortisol
Fludrocortisone
9-Fluoro-17-Hydroxycortisone
Astonin Merck
Astonin-H
Astonin
FCOL
9-Fluorohydrocortisone
9 alpha-Fluoro-17-Hydroxycorticosterone
9 alpha Fludrohydrocortisone

A synthetic mineralocorticoid with anti-inflammatory activity.


Bacillus Bacteriophages
Bacteriophage phi 29
Phage phi 29
Bacteriophage phi 105
Phage phi 105
Bacillus Phages

Viruses whose host is Bacillus. Frequently encountered Bacillus phages include bacteriophage phi 29 and bacteriophage phi 105.


Hospital Distribution System
Clinical Distribution
Hospital Distribution Systems
Distribution Systems, Hospital
Distribution, Clinical
Clinical Distributions
Distribution System, Hospital
Distributions, Clinical

Systems for delivering hospital supplies, food, laundry, etc., to patient care areas.


Antibody-Toxin Hybrids
Chimeric Toxins
Affinotoxins
Toxin-Antibody Conjugates
Toxin Carrier
Toxins, Targeted
Toxin Carriers
Targeted Toxins
Toxins, Chimeric
Toxin-Antibody Hybrids
Toxin Conjugate
Chimeric Toxin
Antibody-Toxin Conjugates
Immunotoxin
Toxin Conjugates
Cytotoxin-Antibody Conjugates
Immunotoxins
Monoclonal Antibody-Toxin Conjugates

Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect.


An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.


A selective aromatase inhibitor effective in the treatment of estrogen-dependent disease including breast cancer.


Residual Disease, Minimal
Minimal Residual Disease
Residual Tumour
Minimal Disease, Residual
Neoplasm, Residual
Residual Tumor
Residual Neoplasm
Residual Cancer

Remnant of a tumor or cancer after primary, potentially curative therapy.


Hydrastis canadensis
Hydrastis
Golden Seal
Goldenseal

A plant genus of the family RANUNCULACEAE. Members contain BERBERINE.


A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.


Amino Acid Permeases
Amino Acid Transport Systems
Amino Acid Transporter
Amino Acid Permease
Amino Acid Transporters

Amino acid transporters found in yeasts, plants and lower organisms. However, the distinction between the terms permease and transporter has not been consistently maintained in the literature.


Common oxidized form of deoxyguanosine in which C-8 position of guanine base has a carbonyl group.


Carbamic Acids
Carbamates
Aminoformic Acids

Derivatives of carbamic acid, H2NC(=O)OH. Included under this heading are N-substituted and O-substituted carbamic acids. In general carbamate esters are referred to as urethanes, and polymers that include repeating units of carbamate are referred to as POLYURETHANES. Note however that polyurethanes are derived from the polymerization of ISOCYANATES and the singular term URETHANE refers to the ethyl ester of carbamic acid.


Secondary Vascular Parkinson Disease
Parkinson Disease, Symptomatic
Secondary Parkinsonism
Parkinsonism, Symptomatic
Parkinson Disease, Secondary
Parkinsonism, Secondary
Atherosclerotic Parkinsonism
Parkinson Disease, Secondary Vascular
Symptomatic Parkinson Disease

Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)


Lipase A (Lysosomal Acid Cholesterol Esterase)

An enzyme that catalyzes the hydrolysis of CHOLESTEROL ESTERS and some other sterol esters, to liberate cholesterol plus a fatty acid anion.


Organizations, Professional
Professional Organizations
Societies

Organizations composed of members with common interests and whose professions may be similar.


Eukaryotic Translation-Initiation Factor 4AIII

A component of eukaryotic initiation factor 4F that as an RNA helicase involved in unwinding the secondary structure of the 5' UNTRANSLATED REGION of MRNA. The unwinding facilitates the binding of the 40S ribosomal subunit.


Piperamic Acid
Pipemidic Acid
Deblaston
Urisan
Nuril
Galusan
Palin
Pipram
Uropipemid

Antimicrobial against Gram negative and some Gram positive bacteria. It is protein bound and concentrated in bile and urine and used for gastrointestinal, biliary, and urinary infections.


Proctocolitis, Ulcerative
Proctocolitis, Hemorrhagic
Hemorrhagic Proctocolitis
Rectocolitis
Proctosigmoiditis
Rectocolitis, Hemorrhagic
Rectocolitis, Ulcerative
Ulcerative Proctocolitis
Rectosigmoiditis
Proctocolitis

Inflammation of the RECTUM and the distal portion of the COLON.


Antiresorptive Drugs
Bone Resorption Inhibitors
Bone Density Conservation Agents
Antiresorptive Agents
Bone Resorption Inhibitory Agents

Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS.


A plant species of the genus SOLANUM, family SOLANACEAE. The starchy roots are used as food. SOLANINE is found in green parts.


Fibroatheroma
Plaque, Atherosclerotic
Atherosclerotic Plaque
Atheromatous Plaques
Atherosclerotic Plaques
Atheroma
Fatty Streak, Arterial
Fibroatheromatous Plaques

Lesions formed within the walls of ARTERIES.


Eukaryotic Initiation Factor-2B, gamma Subunit

Eukaryotic Initiation Factor-2B, beta Subunit

Eukaryotic Initiation Factor-2B, alpha Subunit

Eukaryotic Initiation Factor-2B, delta Subunit

Eukaryotic Initiation Factor-2B, epsilon Subunit

A guanine nucleotide exchange factor that acts to restore EUKARYOTIC INITIATION FACTOR-2 to its GTP bound form.


Cyclic Nucleotide Phosphodiesterases, Type 3B

cGMP-Inhibited Cyclic Nucleotide Phosphodiesterase

Cyclic Nucleotide Phosphodiesterases, Type 3A

Cyclic Nucleotide Phosphodiesterase PDE3 Family

A cyclic nucleotide phosphodiesterase subfamily that is inhibited by the binding of CYCLIC GMP to an allosteric domain found on the enzyme and through phosphorylation by regulatory kinases such as PROTEIN KINASE A and PROTEIN KINASE B. The two members of this family are referred to as type 3A, and type 3B, and are each product of a distinct gene. In addition multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing.


Complement Factor B, Alternative Pathway

A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb.


Olives
Common Olive Tree
Olive Tree
Olea
Olea europaea

A plant genus of the family Oleaceae. The olive fruit is the source of OLIVE OIL.


Quality Indicators, Health Care
Healthcare Global Trigger Tool
Quality Indicators, Healthcare
Health Metrics
Global Trigger Tool, Healthcare

Norms, criteria, standards, and other direct qualitative and quantitative measures used in determining the quality of health care.


Genes, erbA beta
Genes, erbA alpha
Genes, TR alpha
erbA Genes
Genes, erbA-alpha
Genes, THRB
Genes, TR-beta
v-erbA Genes
Genes, erbA
c-erbA Genes
Genes, THRA
Genes, TR beta
v-erbA Oncogenes
Genes, TR-alpha
Genes, erbA-beta
c-erbA Proto-Oncogenes

Viral oncogenes that are homologues of erbA1 (THRA) gene which encodes thyroid hormone receptor alpha. v-erbA Oncogenes potentiate the transforming ability of other oncogenes such as v-erbB by inhibiting spontaneous differentiation of already transformed cells.


beta-Stranded Structures
Protein Conformation, beta-Sheet
beta-Sheets
beta-Strands
Protein Conformation, beta-Strand
beta-Strand
beta-Sheet
beta-Pleated Sheet

A type of secondary structure that occurs between lateral beta strands connected by at least two or three backbone hydrogen bonds. Multiple beta-sheets may associate to form PROTEIN AGGREGATES.


Galanthamine Hydrobromide
Galantamine
Lycoremine
Nivalin
Galanthamine
Reminyl
Nivaline
Razadyne
Galantamin

Name of the FDA approved preparation from J&J.


Thyroliberin
Relefact TRH
Proterelin Tartrate Hydrate
Stimu-TSH
Abbott-38579
Protirelin Tartrate (1:1)
Proterelin Tartrate
Protirelin
Thypinone
Thyrotropin-Releasing Hormone Tartrate
Thyroliberin TRH Merck
TRH Ferring
TRH Prem
Antepan
Thyrotropin-Releasing Factor
Thyrotropin-Releasing Hormone

A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND.


A drug that selectively activates certain subclasses of muscarinic receptors and also activates postganglionic nicotinic receptors. It is commonly used experimentally to distinguish muscarinic receptor subtypes.


Procarboxypeptidase A
PCPA1 Enzyme
Carboxypeptidases A
Procarboxypeptidase A2
Carboxypeptidase A5
Procarboxypeptidase A1
Carboxypeptidase A2
Carboxypeptidase A
Carboxypeptidase A1
PCPA2 Enzyme

Carboxypeptidases that are primarily found the DIGESTIVE SYSTEM that catalyze the release of C-terminal amino acids. Carboxypeptidases A have little or no activity for hydrolysis of C-terminal ASPARTIC ACID; GLUTAMIC ACID; ARGININE; LYSINE; or PROLINE. This enzyme requires ZINC as a cofactor and was formerly listed as EC 3.4.2.1 and EC 3.4.12.2.


Rigid Flatfoot
Flatfoot
Convex Pes Valgus
Rocker-Bottom Foot
Talipes Calcaneovalgus
Vertical Talus
Flatfeet
Vertical Talus, Congenital
Splayfoot
Pes Valgus, Congenital Convex
Flat Foot
Pes Planus
Flexible Flatfoot
Flat Feet
Convex Foot
Acquired Adult Flatfoot Deformity
Talipes Valgus

Progressive acquired flatfoot in which the arch of the foot is flat only when standing. It is often caused by POSTERIOR TIBIAL TENDON DYSFUNCTION.


Hill-Sachs Lesions
Osseous Bankart Lesion
Bony Bankart Lesions
Hill-Sachs Lesion
Bankart Lesions
Bony Bankart Lesion
Bankart Fractures
Bankart Tears
Osseous Bankart Lesions
Bankart Lesion

HUMERAL HEAD defect created by the sharp edge of the anterior GLENOID LABRUM as the humeral head dislocates over it.


Coma, Hyperglycemic Hyperosmolar Nonketotic

Hyperglycemic Hyperosmolar Nonketotic Coma

Hyperosmolar Hyperglycemic Nonketotic Coma

A serious complication of TYPE 2 DIABETES MELLITUS. It is characterized by extreme HYPERGLYCEMIA; DEHYDRATION; serum hyperosmolarity; and depressed consciousness leading to COMA in the absence of KETOSIS and ACIDOSIS.


Carbamate derivative used as an insecticide, acaricide, and nematocide.


Organosilanes
Organosilane Compounds
Organosilicon Compounds

Organic compounds that contain silicon as an integral part of the molecule.


Drynariae Drynaria Polypodiaceae Gusuibu

The fern plant family of the order Polypodiales, class Filicopsida, division Pteridophyta, subkingdom TRACHEOPHYTA.


2-benzofurancarboxamide, 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)-1-piperazinyl)-, hydrochloride (1:1)

A benzofuran, indole, and piperazine derivative that functions as a SEROTONIN UPTAKE INHIBITOR and partial SEROTONIN 5-HT1 RECEPTOR AGONIST. It is used as an ANTIDEPRESSIVE AGENT.


Bio-amplification
Biomagnification
Bio Amplification
Bioamplification
Bioaccumulation
Bio-concentration
Bioconcentration
Bio Concentration
Bio Magnification
Bio-accumulation
Bio-magnification
Bio Accumulation

An increase in the concentration of an exogenous substance in the tissues of organisms higher than surrounding ENVIRONMENT. Accumulation of such XENOBIOTICS at successively higher levels up the FOOD CHAIN is called biomagnification. Bioaccumulation of toxic chemicals (e.g., Lead and DDT) may result in CHEMICALLY-INDUCED DISORDERS.


Astronomical Phenomena
Astronomic Processes
Astronomic Phenomenon
Astrophysical Phenomenon
Astronomical Concepts
Astronomical Processes
Astronomic Process
Astronomical Process
Astrophysical Concepts
Astrophysical Phenomena
Astrophysical Processes
Astronomic Concepts
Astronomic Phenomena

Aggregates of matter in outer space, such as stars, planets, and comets; their properties; and the processes they undergo.


Aquarana clamitans
Green Frog
Lithobates clamitans melanota
Lithobates clamitans
Rana clamitans
Rana clamitans clamitans
Rana clamitans melanota
Frog, Bronze
Northern Green Frog
Frog, Green

A species of the family Ranidae which occurs primarily in the eastern half of the United States and Canada. Two subspecies exist, commonly referred to as green frog (R. c. melanota) and bronze frog (R. c. clamitans).


Biocompatible Artificial Receptors
Receptors, Artificial
Artificial Receptors
Synthetic Receptors
Abiotic Receptors
Biocompatible Synthetic Receptors

Receptors that are created by SYNTHETIC CHEMISTRY TECHNIQUES. They are usually designed to mimic endogenous CELL SURFACE RECEPTORS.


Nursing Protocols
Protocols, Nursing
Nursing Assessment
Assessment, Nursing

Evaluation of the nature and extent of nursing problems presented by a patient for the purpose of patient care planning.


Dalfampridine
4-Aminopyridine
VMI-103
Fampridine-SR
Pymadine
4-Aminopyridine Sustained Release

One of the POTASSIUM CHANNEL BLOCKERS with secondary effect on calcium currents which is used mainly as a research tool and to characterize channel subtypes.


Aphrodisiac Effects
Aphrodisiacs
Aphrodisiac Effect

Chemical agents or ODORANTS that stimulate sexual desires. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


Transport Proteins
Binding Protein
Carrier Proteins
Binding Proteins

Proteins that bind or transport specific substances in the blood, within the cell, or across cell membranes.


MAP Kinase Signaling System
p38 Kinase Signaling Pathway
JNK Pathway
MAP Kinase Signaling Cascades
ERK Pathway
MAP Kinase Modules
ERK1-2 Pathway
p38 Kinase Pathway
MAP Kinase Cascade
MAP Kinase Signaling Pathways
JNK Signaling Pathway
ERK1 and ERK2 Pathway
MEK-ERK Pathway
ERK Signal Tranduction Pathway

An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.


5-HT2 Antagonist
Serotonin 5-HT2C Receptor Antagonists
5-HT2B Antagonist
Serotonin 5-HT2A Receptor Antagonists
Serotonin 5-HT2 Receptor Antagonists
5-HT2A Antagonist
Serotonin 5-HT2B Receptor Antagonists
5-HT2C Antagonist

Drugs that bind to but do not activate SEROTONIN 5-HT2 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT2 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more specific 5-HT2 receptor subtypes.


Chronic Urticaria
Chronic Autoimmune Urticaria
Chronic Spontaneous Urticaria
Chronic Idiopathic Urticaria
Idiopathic Chronic Urticaria
CIndU
Chronic Inducible Urticaria
Autoimmune Urticaria

Wheals and/or angioedema presented with daily symptoms lasting for more than 6 weeks. It may be classified into chronic spontaneous and chronic inducible urticaria depending on whether a specific trigger can be linked to the development of vascular reaction.


Diagnosis, Psychiatric
Mental Disorders
Behavior Disorders
Psychiatric Diseases
Psychiatric Illness
Psychiatric Disorders
Mental Disorders, Severe
Psychiatric Diagnosis

Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.


Mice, ICR
Mouse, Inbred ICRC
Mice, Inbred ICRC
Mouse, ICR
Mice, Inbred ICR
Mouse, Inbred ICR

An inbred strain of mouse that is used as a general purpose research strain, for therapeutic drug testing, and for the genetic analysis of CARCINOGEN-induced COLON CANCER.


Evolution, Neutral
Genetic Drift
Drift, Genetic
Neutral Evolution

The fluctuation of the ALLELE FREQUENCY from one generation to the next.


A cyclohexane and triazole derivative that acts as an antagonist of the CCR5 RECEPTOR. It prevents infection by HIV-1 virus strains which use CCR5 as a co-receptor for membrane fusion and cellular entry.


Dimethindene Maleate
Dimetindene
Dimethpyrindene
Forhistal
Fenistil
Dimethindene

A histamine H1 antagonist. It is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies.


United States National Academy of Sciences

A United States organization of distinguished scientists and engineers established for the purpose of investigating and reporting upon any subject of art or science as requested by any department of government. The National Research Council organized by NAS serves as the principal operating agency to stimulate and support research.


Nociceptive Pain
Tissue Pain
Somatic Pain

Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.


Teclea
Fortunella
Raulinoa
Australian Wild Lime
Kumquat
Sarcomelicope
Melicope
Glycosmis
Rutaceae
Severinia
Microcitrus
Acronychia
Vepris
Lime, Australian Wild
Bauerella
Haplophyllum
Swinglea
Agathosma
Atalantia
Zieria

The common name of stinkwood is also used for OCOTEA (a genus in the family LAURACEAE).


Conjunctiva
Tunica Conjunctiva
Plicae Semilunares of Conjunctiva
Palpebral Conjunctiva
Plica Semilunaris of Conjunctiva
Bulbar Conjunctiva

Conjunctiva covering the anterior pericorneal surface of the eyeball.


Glycosidic antibiotic from Streptomyces griseus used as a fluorescent stain of DNA and as an antineoplastic agent.


Insertion Sequence Elements
DNA Transposons
DNA Insertion Elements
DNA Transposable Elements
Sequence Elements, Insertion
Elements, Insertion Sequence
Tn Elements
IS Elements
Transposable Elements

Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.


Skin Physiological Process
Skin Physiological Phenomenon
Skin Physiological Phenomena
Physiology, Skin
Skin Physiology
Skin Physiological Processes
Skin Physiological Concepts

The functions of the skin in the human and animal body. It includes the pigmentation of the skin.


Bylaws
Constitution and Bylaws
Constitutions
Constitution

The fundamental principles and laws adopted by an organization for the regulation and governing of its affairs.


HESW
High-Energy Shock Waves
Shock Waves, Ultrasonic
Shock Waves, High-Energy
High Energy Shock Waves
Shockwaves, Ultrasonic

High-amplitude compression waves, across which density, pressure, and particle velocity change drastically. The mechanical force from these shock waves can be used for mechanically disrupting tissues and deposits.