Aortic Arch Syndromes
Aortic Arch Syndrome

Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.


The expected function of a member of the medical profession.


Acetylserotonin O-Methyltransferase
Hydroxyindole O-Methyltransferase
HIOMT
Oxyindol-O-Methyltransferase
Acetylserotonin Methyltransferase

An enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to N-acetylserotonin to form N-acetyl-5-methoxytryptamine (MELATONIN).


Encephalitis, Infectious
Infectious Encephalitis
Encephalitis Infection

Brain inflammation caused by an infectious agent.


Toluylene Red
C.I. Basic Red 5
Nuclear Fast Red (Basic Dye)
Neutral Red

A vital dye used as an indicator and biological stain. Various adverse effects have been observed in biological systems.


Vanadate
Metavanadate
Monovanadate
Sodium Vanadate
Vanadyl
Vanadates
Orthovanadate
Oxyvanadium
Decavanadate

Oxyvanadium ions in various states of oxidation. They act primarily as ion transport inhibitors due to their inhibition of Na(+)-, K(+)-, and Ca(+)-ATPase transport systems. They also have insulin-like action, positive inotropic action on cardiac ventricular muscle, and other metabolic effects.


Chromosome Mapping, Physical
Physical Chromosome Mapping
Physical Mapping (Genetics)

Mapping of the linear order of genes on a chromosome with units indicating their distances by using methods other than genetic recombination. These methods include nucleotide sequencing, overlapping deletions in polytene chromosomes, and electron micrography of heteroduplex DNA. (From King & Stansfield, A Dictionary of Genetics, 5th ed)


CD135 Antigens
CD135 Antigen
Antigens, CD135
Fetal Liver Kinase-2
fms-Like Tyrosine Kinase 3
Stem Cell Tyrosine Kinase 1
Fetal Liver Kinase-3

A receptor tyrosine kinase that is involved in HEMATOPOIESIS. It is closely related to FMS PROTO-ONCOGENE PROTEIN and is commonly mutated in acute MYELOID LEUKEMIA.


Hyperostosis, Diffuse Idiopathic Skeletal

Diffuse Idiopathic Skeletal Hyperostosis

Ankylosing Vertebral Hyperostosis with Tylosis

A disease of elderly men characterized by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions.


Records, Dental
Dental Record
Dental Records
Record, Dental

Data collected during dental examination for the purpose of study, diagnosis, or treatment planning.


Central retinal artery and its branches. It arises from the ophthalmic artery, pierces the optic nerve and runs through its center, enters the eye through the porus opticus and branches to supply the retina.


A family of voltage-gated eukaryotic porins that form aqueous channels. They play an essential role in mitochondrial CELL MEMBRANE PERMEABILITY, are often regulated by BCL-2 PROTO-ONCOGENE PROTEINS, and have been implicated in APOPTOSIS.


Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.


Fenestra Cochleae
Cochlear Round Window
Round Window, Ear
Round Window of Ear

Fenestra of the cochlea, an opening in the basal wall between the MIDDLE EAR and the INNER EAR, leading to the cochlea. It is closed by a secondary tympanic membrane.


AGAMOUS Protein, Arabidopsis
AGAMOUS 1 Protein

A plant homeotic protein involved in the development of stamens and carpels of Arabidopsis thaliana. It is a DNA-binding protein that contains the MADS-box domain. It is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.


Cine Magnetic Resonance Imaging
Magnetic Resonance Imaging, Cine
Cine MRI

A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.


Brachyspira hyodysenteriae
Serpula hyodysenteriae
Treponema hyodysenteriae
Serpulina hyodysenteriae

A species of anaerobic, spiral bacteria that was formerly classified as Serpulina hyodysenteriae and Treponema hyodysenteriae (and for a short while, Serpula hyodysenteriae). This organism is the agent of swine dysentery.


A plant species of the genus OCIMUM, family LAMIACEAE. It is a condiment with carminative properties.


Blood Glucose
Glucose, Blood
Blood Sugar


Vitamin H
Medobiotin
Biotin Hermes
Biokur
Biotin-Ratiopharm
Medebiotin
Biotine Roche
Gabunat
Deacura
Biodermatin
Biotin
Rombellin
Biotin Gelfert

A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.


A continuous cell line that is a substrain of SWISS 3T3 CELLS developed though clonal isolation. The mouse fibroblast cells undergo an adipose-like conversion as they move to a confluent and contact-inhibited state.


A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN.


Surgery Department, Hospital
Department, Hospital Surgery
Surgery Departments, Hospital
Surgical Service, Hospital
Hospital Surgery Department

Hospital department which administers all departmental functions and the provision of surgical diagnostic and therapeutic services.


Group of chemokines with the first two cysteines separated by three amino acids. CX3C chemokines are chemotactic for natural killer cells, monocytes, and activated T-cells.


Jehovah's Witnesses
Watchtower Bible and Tract Society

Members of a religious denomination founded in the United States during the late 19th century in which active evangelism is practiced, the imminent approach of the millennium is preached, and war and organized government authority in matters of conscience are strongly opposed (from American Heritage Dictionary of the English Language, 4th ed). Jehovah's Witnesses generally refuse blood transfusions and other blood-based treatments based on religious belief.


Chromatin Assembly Complex-1, p60 Subunit

Chromatin Assembly Complex-1, p150 Subunit

A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.


Receptor, Interleukin-15
Receptors, Interleukin-15
IL-15 Receptor
Interleukin-15 Receptor
Interleukin-15 Receptors

Cell surface receptors for INTERLEUKIN-15. They are widely-distributed heterotrimeric proteins consisting of the INTERLEUKIN-15 RECEPTOR ALPHA SUBUNIT, the INTERLEUKIN-2, 15 RECEPTOR BETA SUBUNIT, and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN.


The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPIPHYSES. It is usually caused by somatotroph hyperplasia or a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. These patients are of abnormally tall stature, more than 3 standard deviations above normal mean height for age.


Metandienone Dehydromethyltestosterone Metanabol Methandienone Methandrostenolone Dianabol Nerobol

A synthetic steroid with anabolic properties that are more pronounced than its androgenic effects. It has little progestational activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1188)


Cucumber Mosaic Virus Satellite RNA
Cucumber Mosaic Virus Satellite

A satellite RNA (not a satellite virus) which has several types. Different cucumoviruses can act as helper viruses for different types.


Phenolic metacyclophanes derived from condensation of PHENOLS and ALDEHYDES. The name derives from the vase-like molecular structures. A bracketed [n] indicates the number of aromatic rings.


Oncorhynchus keta
Salmon, Dog
Salmon, Chum

An anadromous species of SALMON found in the streams of the Pacific coast from Sacramento north, and also common in Japan. It is used frequently in genetic and other medical research.


A synthetic progestational agent with actions similar to those of PROGESTERONE. This racemic or (+-)-form has about half the potency of the levo form (LEVONORGESTREL). Norgestrel is used as a contraceptive, ovulation inhibitor, and for the control of menstrual disorders and endometriosis.


Dental Esthetic
Aesthetics, Dental
Cosmetic Dentistry
Esthetics, Dental
Dental Esthetics
Esthetic, Dental

Skills, techniques, standards, and principles used to improve the art and symmetry of the teeth and face to improve the appearance as well as the function of the teeth, mouth, and face. (From Boucher's Clinical Dental Terminology, 4th ed, p108)


T-Cell Antigen Receptor
T-Cell Receptors
Receptors, Antigen, T-Cell
Antigen Receptors, T-Cell
Receptors, T-Cell Antigen
T-Cell Receptor

Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.


Research Embryo Creation
Embryo Creation, Research

The creation of embryos specifically for research purposes.


Refraction of LIGHT effected by the media of the EYE.


Genes whose entire sequences are contained within other genes.


Lymphangiectasis, Intestinal
Lymphangiectasia, Intestinal
Intestinal Lymphangiectasis

Dilatation of the intestinal lymphatic system usually caused by an obstruction in the intestinal wall. It may be congenital or acquired and is characterized by DIARRHEA; HYPOPROTEINEMIA; peripheral and/or abdominal EDEMA; and PROTEIN-LOSING ENTEROPATHIES.


Spermine Synthase
Spermine Synthetase
Spermidine Aminopropyltransferase

An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to spermidine in the biosynthesis of spermine. It has an acidic isoelectric point at pH 5.0. EC 2.5.1.22.


Dynamin I
Dynamin-1
Dynamin D100
DNM1 Gene Product, Dynamin

A subtype of dynamin found primarily in the NEURONS of the brain.


A usually benign tumor made up predominantly of myoepithelial cells.


Retinal Horizontal Cells
Horizontal Cells, Retinal

NEURONS in the inner nuclear layer of the RETINA that synapse with both the RETINAL PHOTORECEPTOR CELLS and the RETINAL BIPOLAR CELLS, as well as other horizontal cells. The horizontal cells modulate the sensory signal.


A species of bacteria present in man and many kinds of animals and birds, often causing infertility and/or abortion.


Myxoma virus
Poxvirus Myxomatis
Myxomatosis Virus

The type species of LEPORIPOXVIRUS causing infectious myxomatosis, a severe generalized disease, in rabbits. Tumors are not always present.


Patients' guests and rules for visiting.


Rats, SHR
Rats, Inbred SHR
Rats, Spontaneously Hypertensive

A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.


Antitubercular Agents
Antitubercular Drugs
Tuberculostatic Agents

Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.


Apolipoproteins L
Apolipoprotein L Family
ApoL Proteins

A family of apolipoproteins occurring in humans that are structurally similar to B-CELL LEUKEMIA 2 FAMILY PROTEINS. In addition to their roles in cholesterol and lipid transport, they are expressed by MYELOID CELLS and ENDOTHELIAL CELLS during INFLAMMATION and may function to promote CELL DEATH.


Therapy, Renal Replacement
Renal Replacement Therapy
Kidney Replacement Therapy
Therapy, Kidney Replacement
Replacement Therapy, Kidney
Replacement Therapy, Renal

Procedures which temporarily or permanently remedy insufficient cleansing of body fluids by the kidneys.


An element with the atomic symbol Se, atomic number 34, and atomic weight 78.97. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.


A class of compounds composed of repeating 5-carbon units of HEMITERPENES.


Fluid obtained by THERAPEUTIC IRRIGATION or washout of the nasal cavity and NASAL MUCOSA. The resulting fluid is used in cytologic and immunologic assays of the nasal mucosa such as with the NASAL PROVOCATION TEST in the diagnosis of nasal hypersensitivity.


A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.


Public Health Administration
Administration, Public Health

Management of public health organizations or agencies.


Specificity Protein 4 Transcription Factor

A specificity protein transcription factor that is expressed primarily in the CENTRAL NERVOUS SYSTEM.


An enzyme that catalyzes the formation of phosphoribosyl pyrophosphate from ATP and ribose-5-phosphate. EC 2.7.6.1.


Bradykinin Receptor Inhibitors
Bradykinin Receptor Blockers
Bradykinin Receptor Antagonists
Bradykinin Antagonists

Compounds and drugs that inhibit ligand binding or cellular signaling by BRADYKININ RECEPTORS.


Kidney Failure, Chronic
End-Stage Kidney Disease
End-Stage Renal Disease
Renal Failure, End-Stage
Renal Disease, End-Stage
ESRD
Chronic Kidney Failure
Renal Failure, Chronic

The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.


Nitroderm TTS
Tridil
Susadrin
Nitroderm
Transderm Nitro
Glyceryl Trinitrate
Nitrol
Trinitrolong
Dynamite
Sustonit
Nitro-Bid
Perlinganit
Nitrolan
Sustac
Nitrong
Gilustenon
Nitroglycerin
Nitrostat
Sustak
Nitrangin
Nitrospan
Nitro-Dur
Nitroglyn
Anginine
Trinitrin
Nitrocard

A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.


Cartilage-Derived Morphogenetic Protein 1

A growth differentiation factor that plays a role in early CHONDROGENESIS and joint formation.


Behavior, Compulsive
Compulsive Behavior

The behavior of performing an act persistently and repetitively without it leading to reward or pleasure. The act is usually a small, circumscribed behavior, almost ritualistic, yet not pathologically disturbing. Examples of compulsive behavior include twirling of hair, checking something constantly, not wanting pennies in change, straightening tilted pictures, etc.


Nerve fibers liberating catecholamines at a synapse after an impulse.


Anxiety, Separation
Separation Anxiety Disorder

Anxiety experienced by an individual upon separation from a person or object of particular significance to the individual.


Convallariaceae Polianthes Hesperaloe Muscari Anemarrhenaceae Agavaceae Hyacinthaceae Asparagaceae Nolinoideae


Miniature Swine
Swine, Miniature
Minipigs

Genetically developed small pigs for use in biomedical research. There are several strains - Yucatan miniature, Sinclair miniature, and Minnesota miniature.


Baculoviral IAP Repeat-containing Protein 5

An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.


The 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. They act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics.


Occupational Health Physicians
Company Physicians
Physicians, Occupational Health

Physicians employed in a company or corporate setting that is generally not in the health care industry.


Transient Receptor Potential Channels, Type C

Transient Receptor Potential Cation Channel Subfamily C

A subgroup of TRP cation channels that contain 3-4 ANKYRIN REPEAT DOMAINS and a conserved C-terminal domain. Members are highly expressed in the CENTRAL NERVOUS SYSTEM. Selectivity for calcium over sodium ranges from 0.5 to 10.


Sulfinylbis(methane)
Sclerosol
DMSO
Rheumabene
Dimethylsulphinyl
Dimexide
Rimso 100
Dimethylsulphoxide
Dimethyl Sulfoxide
Dimethylsulfoxide
Rimso-50
Dimethyl Sulphoxide
Rimso

A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.


Hypertensin
Angiotensin Amide
5-Valine-Angiotensin II Amide
1-Asparagine-5-valine Angiotensin II
Angiotensinamide

The octapeptide amide of bovine angiotensin II used to increase blood pressure by vasoconstriction.


A species of RHODOCOCCUS found in soil, herbivore dung, and in the intestinal tract of cows, horses, sheep, and pigs. It causes bronchopneumonia in foals and can be responsible for infection in humans compromised by immunosuppressive drug therapy, lymphoma, or AIDS.


A viral disease of cloven-hoofed animals caused by MORBILLIVIRUS. It may be acute, subacute, or chronic with the major lesions characterized by inflammation and ulceration of the entire digestive tract. The disease was declared successfully eradicated worldwide in 2010.


Emergency Contraception
Contraception, Postcoital
Fertility Control, Postcoital

Means of postcoital intervention to avoid pregnancy, such as the administration of POSTCOITAL CONTRACEPTIVES to prevent FERTILIZATION of an egg or implantation of a fertilized egg (OVUM IMPLANTATION).


Bland White Garland Syndrome
ALCAPA Syndrome
ALCAPA
Bland-White-Garland Syndrome

A congenital coronary vessel anomaly in which the left main CORONARY ARTERY originates from the PULMONARY ARTERY instead of from AORTA. The congenital heart defect typically results in coronary artery FISTULA; LEFT-SIDED HEART FAILURE and MITRAL VALVE INSUFFICIENCY during the first months of life.


Arylsulfatase A
Cerebroside-Sulfatase
Sulfatidate Sulfatase

An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.


Hemorrhage, Cerebral
Cerebral Hemorrhage
Brain Hemorrhage, Cerebral
Hemorrhage, Cerebrum
Cerebral Parenchymal Hemorrhage
Intracerebral Hemorrhage

Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.


Ehrlichia risticii
Neorickettsia risticii

A species of gram-negative bacteria in the genus NEORICKETTSIA, family ANAPLASMATACEAE.


Staphylococcal Infections
Staphylococcus aureus Infection
Infections, Staphylococcal

Infections with bacteria of the genus STAPHYLOCOCCUS.


Sequence Inversion
Inverted Sequence
Inversion, Sequence

The deletion and reinsertion of a segment of a nucleic acid sequence in the same place, but flipped in an opposite orientation.


Analysis of Variance
Variance Analysis
ANOVA
Analysis, Variance

A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.


The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.


Exo-alpha-Sialidase
N-Acylneuraminate Glycohydrolases
Oligosaccharide Sialidase
Neuraminidase
Sialidase

An enzyme that catalyzes the hydrolysis of alpha-2,3, alpha-2,6-, and alpha-2,8-glycosidic linkages (at a decreasing rate, respectively) of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid, and synthetic substrate. (From Enzyme Nomenclature, 1992)


Triose Sugar Alcohols
Glycerol Derivatives

Sugar alcohol molecules that contain three carbons.


Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis.


A thin leaf-shaped cartilage that is covered with LARYNGEAL MUCOSA and situated posterior to the root of the tongue and HYOID BONE. During swallowing, the epiglottis folds back over the larynx inlet thus prevents foods from entering the airway.


Confinement of an individual to bed for therapeutic or experimental reasons.


Excision, in part or whole, of an INTERVERTEBRAL DISC. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.


von Willebrand Disease, Recessive Form
Vascular Pseudohemophilia
Von Willebrand's Factor Deficiency
von Willebrand's Disease
Angiohemophilia
Hemophilia, Vascular
von Willebrand's Diseases
von Willebrand Diseases
Von Willebrand Disorder
von Willebrand Disease

Group of hemorrhagic disorders in which the VON WILLEBRAND FACTOR is either quantitatively or qualitatively abnormal. They are usually inherited as an autosomal dominant trait though rare kindreds are autosomal recessive. Symptoms vary depending on severity and disease type but may include prolonged bleeding time, deficiency of factor VIII, and impaired platelet adhesion.


Peanut and Tree Nut Hypersensitivity
Peanut and Nut Allergy
Tree Nut and Peanut Allergy
Peanut and Nut Allergies
Nut and Peanut Allergy
Nut and Peanut Hypersensitivity
Peanut and Tree Nut Allergies
Nut and Peanut Allergies
Peanut and Tree Nut Allergy

Allergic reaction to tree nuts and peanuts, including other LEGUMES, that is triggered by the immune system. It includes co-sensitization to other food (e.g., sesame seed).


Lightning Injuries
Lightning Stroke
Injuries, Lightning

Accidental injuries caused by brief high-voltage electrical discharges during thunderstorms. Cardiopulmonary arrest, coma and other neurologic symptoms, myocardial necrosis, and dermal burns are common. Prompt treatment of the acute sequelae, including cardiopulmonary resuscitation, is indicated for survival.


Niche, Ecological
Systems, Ecological
Ecologic System
System, Ecological
Habitat
Biome
Ecologic Systems
Ecosystem
Ecological System

A functional system which includes the organisms of a natural community together with their environment. (McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)


Centers, Poison Control
Poison Control Centers

Facilities which provide information concerning poisons and treatment of poisoning in emergencies.


Communicable Diseases, Imported
Imported Diseases, Infectious
Imported Infections
Imported Infectious Diseases

Infectious diseases originating in one geographically delineated ecosystem that are carried (by travel or immigration) to another geographically delineated ecosystem by an infected individual, animal, or disease vector.


Axonal Injury, Diffuse
DAI (Diffuse Axonal Injury)
Diffuse Axonal Injury

A relatively common sequela of blunt head injury, characterized by a global disruption of axons throughout the brain. Associated clinical features may include NEUROBEHAVIORAL MANIFESTATIONS; PERSISTENT VEGETATIVE STATE; DEMENTIA; and other disorders.


Cell Membrane
Cytoplasmic Membrane
Plasma Membrane

The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.


A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.


A chronic and relatively benign subepidermal blistering disease usually of the elderly and without histopathologic acantholysis.


Polysaccharides composed of D-fructose units.


40S Ribosome Subunits
Small Ribosomal Subunits, Eukaryotic
Ribosomal Subunits, 40S
Small Ribosome Subunits, Eukaryotic
Ribosomal Subunits, Small, Eukaryotic
40S Ribosomal Subunits
Eukaryotic Small Ribosome Subunits
Ribosome Subunits, 40S
Eukaryotic Small Ribosomal Subunits
Ribosome Subunits, Small, Eukaryotic

The small subunit of the 80s ribosome of eukaryotes. It is composed of the 18S RIBOSOMAL RNA and 32 different RIBOSOMAL PROTEINS.


Tobramycin, Dexamethasone Drug Combination

A topical preparation of tobramycin and dexamethasone that is used for treating or preventing superficial bacterial infections of the eye.


MNNG Methylnitrosonitroguanidine Nitrosomethylnitroguanidine Nitrosonitromethylguanidine N-Methyl-N'-nitro-N-nitrosoguanidine Methylnitronitrosoguanidine

A nitrosoguanidine derivative with potent mutagenic and carcinogenic properties.


Erythrosine B
F D & C #3
FD & C Red No. 3
Erythrosine
2',4',5',7'-Tetraiodofluorescein
FDC Red No. 3
Erythrosin B
Erythrosin

A tetraiodofluorescein used as a red coloring in some foods (cherries, fish), as a disclosure of DENTAL PLAQUE, and as a stain of some cell types. It has structural similarity to THYROXINE.


Premenopausal Period
Pre-menopausal Period
Premenopause
Pre-Menopause

The period before MENOPAUSE. In premenopausal women, the climacteric transition from full sexual maturity to cessation of ovarian cycle takes place between the age of late thirty and early fifty.


p-Aminosalicylic Acid, Aluminum (2:1) Salt

p-Aminosalicylic Acid Monopotassium Salt

p-Aminosalicylic Acid, Monosodium Salt, Dihydrate

p-Aminosalicylic Acid, Calcium (2:1) Salt

An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.


Receptors, Cholecalciferol
Calcitriol Receptors
1,25-Dihydroxycholecalciferol Receptor
Calcitriol Receptor
Vitamin D 3 Receptor
Vitamin D 3 Receptors
Vitamin D3 Receptors
1,25-Dihydroxyvitamin D 3 Receptor
1,25-Dihydroxyvitamin D3 Receptors
1,25-Dihydroxyvitamin D3 Receptor
Receptors, Vitamin D 3
Receptors, Vitamin D
Receptors, Calcitriol
Receptors, Vitamin D3
Vitamin D Receptors
Vitamin D3 Receptor
Receptors, 1,25-Dihydroxyvitamin D 3
Vitamin D Receptor
1,25-Dihydroxycholecalciferol Receptors
Cholecalciferol Receptors

Proteins, usually found in the cytoplasm, that specifically bind calcitriol, migrate to the nucleus, and regulate transcription of specific segments of DNA with the participation of D receptor interacting proteins (called DRIP). Vitamin D is converted in the liver and kidney to calcitriol and ultimately acts through these receptors.


Disease Vectors
Infectious Disease Vectors

Invertebrates or non-human vertebrates which transmit infective organisms from one host to another.


Esterified Estrogens (USP)
Estrogens, Esterified (USP)

A pharmaceutical preparation containing a mixture of esterified estrogens derived from estrogen sulfates, principally from ESTRONE sulfate. Esterified estrogen content should be 75-85% of the estrone sulfate and 6-15% of the EQUILIN sulfate.


Left Atrium
Right Atrium
Heart Atria
Heart Atrium

The chambers of the heart, to which the BLOOD returns from the circulation.


Mouse t-Haplotype
t-Complex Genome Region
t-Complex Region

A 20 cM region of mouse chromosome 17 that is represented by a least two HAPLOTYPES. One of the haplotypes is referred to as the t-haplotype and contains an unusual array of mutations that affect embryonic development and male fertility. The t-haplotype is maintained in the gene pool by the presence of unusual features that prevent its recombination.


Embolotherapy
Embolization, Therapeutic
Therapeutic Embolization

A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.


An acidifying agent that has expectorant and diuretic effects. Also used in etching and batteries and as a flux in electroplating.


Baylisascaris procyonis Infection
Raccoon Roundworm Encephalitis
Raccoon Roundworm Infections
Baylisascaris Infection
Ascaridida Infections
Infections, Ascaridida

Infections with nematodes of the order ASCARIDIDA.


Slim Disease
Wasting Syndrome, HIV
Wasting Disease, HIV
HIV Wasting Syndrome
HIV Wasting Disease
AIDS Wasting Syndrome

Involuntary weight loss of greater than 10 percent associated with intermittent or constant fever and chronic diarrhea or fatigue for more than 30 days in the absence of a defined cause other than HIV infection. A constant feature is major muscle wasting with scattered myofiber degeneration. A variety of etiologies, which vary among patients, contributes to this syndrome. (From Harrison's Principles of Internal Medicine, 13th ed, p1611).


The room or rooms in which the physician and staff provide patient care. The offices include all rooms in the physician's office suite.


Compounds that bind to and inhibit the action of 5-LIPOXYGENASE-ACTIVATING PROTEINS.


Drug-Induced Abnormalities
Abnormalities, Drug-Induced

Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.


Protein Methyltransferases
Protein Methylases

Enzymes that catalyze the methylation of amino acids after their incorporation into a polypeptide chain. S-Adenosyl-L-methionine acts as the methylating agent. EC 2.1.1.


Keratosis, Oral
Leukokeratosis, Oral
Leukoplakia, Oral

A white patch seen on the oral mucosa. It is considered a premalignant condition and is often tobacco-induced. When evidence of Epstein-Barr virus is present, the condition is called hairy leukoplakia (LEUKOPLAKIA, HAIRY).


Very Low Density Lipoprotein Cholesterol

Cholesterol which is contained in or bound to very low density lipoproteins (VLDL). High circulating levels of VLDL cholesterol are found in HYPERLIPOPROTEINEMIA TYPE IIB. The cholesterol on the VLDL is eventually delivered by LOW-DENSITY LIPOPROTEINS to the tissues after the catabolism of VLDL to INTERMEDIATE-DENSITY LIPOPROTEINS, then to LDL.


Pharmaceuticals, Dental
Pharmaceutical Preparations, Dental
Dental Drugs
Drugs, Dental


DNA found in the ENVIRONMENT that is from the residual biological materials of the organisms in the environment.


Sister Mary Joseph's Nodule
Sister Joseph's Nodule

Metastatic lesion of the UMBILICUS associated with intra-abdominal neoplasms especially of the GASTROINTESTINAL TRACT or OVARY.


Therapeutic Electrical Stimulation
Interferential Current Electrotherapy
Therapy, Electric Stimulation
Electrotherapy
Electric Stimulation Therapy
Therapeutic Electric Stimulation
Electrical Stimulation Therapy

A type of electric stimulation therapy using a current produced by mixing two slightly out-of-phase medium frequency currents.


Bovine Spongiform Encephalopathy
Spongiform Encephalopathy, Bovine
Mad Cow Disease
BSE (Bovine Spongiform Encephalopathy)
Encephalopathy, Bovine Spongiform
Encephalitis, Bovine Spongiform

A transmissible spongiform encephalopathy of cattle associated with abnormal prion proteins in the brain. Affected animals develop excitability and salivation followed by ATAXIA. This disorder has been associated with consumption of SCRAPIE infected ruminant derived protein. This condition may be transmitted to humans, where it is referred to as variant or new variant CREUTZFELDT-JAKOB SYNDROME. (Vet Rec 1998 Jul 25;143(41):101-5)


A general class of integral membrane proteins that transport ions across a membrane against an electrochemical gradient.


Chemodenervation
Nerve Blockade
Nerve Block
Chemical Neurolysis

Interruption of NEURAL CONDUCTION in peripheral nerves or nerve trunks by the injection of a local anesthetic agent (e.g., LIDOCAINE; PHENOL; BOTULINUM TOXINS) to manage or treat pain.


The flattened, funnel-shaped expansion connecting the URETER to the KIDNEY CALICES.


A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)


Chromosomes, Human, Pair 18
Chromosome 18

A specific pair of GROUP E CHROMOSOMES of the human chromosome classification.


Administration, Health Services
Health Services Administration

The organization and administration of health services dedicated to the delivery of health care.


Fluopromazine Triflupromazine Siquil Trifluopromazine

A phenothiazine used as an antipsychotic agent and as an antiemetic.


Contracture, Volkmann
Volkmann's Ischemic Contracture
Volkmann Contracture
Ischemic Contracture

A type of permanent damage to muscles and nerves that results from prolonged lack blood flow to those tissues. It is characterized by shortening and stiffening of the muscles.


Blood Platelet Number
Blood Platelet Count
Platelet Count
Platelet Number

The number of PLATELETS per unit volume in a sample of venous BLOOD.


Neural Constitutive Nitric Oxide Synthase

A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in NERVE TISSUE.


Hyperimidodipeptiduria
Prolidase Deficiency
Imidodipeptidase Deficiency

Rare autosomal recessive disorder of metabolism due to mutations in the prolidase gene. It is characterized by recurrent lower extremity skin ulcers, recurrent infections, and FACIES, often with INTELLECTUAL DISABILITY.


Lactate Dehydrogenase
L-Lactate Dehydrogenase

A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.


Material applied to the tissue side of a denture to provide a soft lining to the parts of a denture coming in contact with soft tissue. It cushions contact of the denture with the tissues.


Mouse Encephalomyelitis Virus
Mouse Elberfeld Virus
Maus Elberfeld virus
Murine Encephalomyelitis Virus
Encephalomyelitis Virus, Murine

A strain of ENCEPHALOMYOCARDITIS VIRUS, a species of CARDIOVIRUS, usually causing an inapparent intestinal infection in mice. A small number of mice may show signs of flaccid paralysis.


The species Canis latrans in the family CANIDAE, a smaller relative of WOLVES. It is found in the Western hemisphere from Costa Rica to Alaska.


Macrocyclic Lactams
Lactams, Macrocyclic
Ansamycins

A group of LACTAMS with an aliphatic ansa chain which is linked to a BENZENE or naphthalene chromophore. Included are RIFAMYCINS, naphthomycins, geldanamycins, streptovaricins, and maytansinoids.


Calcium-Dependent Neutral Proteinase
Calpain II
Calpain I
Desminase
Ca2+-Activated Protease
Calcium-Activated Protease
Calpain
Calcium-Activated Neutral Proteinase
Calcium-Activated Neutral Protease
Calcium-Dependent Neutral Protease

Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from SMOOTH MUSCLE; CARDIAC MUSCLE; liver; platelets; and erythrocytes. Two subclasses having high and low calcium sensitivity are known. Removes Z-discs and M-lines from myofibrils. Activates phosphorylase kinase and cyclic nucleotide-independent protein kinase. This enzyme was formerly listed as EC 3.4.22.4.


Sinus Histiocytosis with Massive Lymphadenopathy

Benign, non-Langerhans-cell, histiocytic proliferative disorder that primarily affects the lymph nodes. It is often referred to as sinus histiocytosis with massive lymphadenopathy.


Nuclear Antigens, Herpesvirus 4, Human
EBV Nuclear Antigens
Herpesvirus 4, Human Nuclear Antigens
Epstein-Barr Virus Nuclear Antigens

Nuclear antigens encoded by VIRAL GENES found in HUMAN HERPESVIRUS 4. At least six nuclear antigens have been identified.


Implants, Breast
Breast Prosthesis, Internal
Breast Implants

Implants used to reconstruct and/or cosmetically enhance the female breast. They have an outer shell or envelope of silicone elastomer and are filled with either saline or silicone gel. The outer shell may be either smooth or textured.


The movement of molecules from one location to another as effected by temperature changes.


A macrolide antibiotic produced by Streptomyces kitasatoensis. The drug has antimicrobial activity against a wide spectrum of pathogens.


SLC31 Proteins
Solute Carrier Family 31 Proteins

Eukaryotic copper transport proteins that function primarily in the transport of dietary or environmental COPPER.


Healthcare Quality, Access, and Evaluation

Health Care Quality, Access, and Evaluation

The concept concerned with all aspects of the quality, accessibility, and appraisal of health care and health care delivery.


Cytochrome P450 PB-1
Cytochrome P450 MP-8
Cytochrome P450 MP-4
CYP2C9
Cytochrome P-450 CYP2C9
CYPIIC9

A cytochrome P-450 subtype that has specificity for acidic XENOBIOTICS. It oxidizes a broad range of important clinical drugs that fall under the categories of NONSTEROIDAL ANTI-INFLAMMATORY AGENTS; HYPOGLYCEMIC AGENTS; ANTCOAGULANTS; and DIURETICS.


SAPS 3
SAPS III
Simplified Acute Physiology Score
SAPS II
SAPS 2

A severity of disease classification system designed to measure the severity of disease for patients aged 15 and over admitted to intensive care units.


A plant genus of the family LILIACEAE that contains cholestane glycosides (CHOLESTANES).


Apc4 Subunit, Anaphase-Promoting Complex-Cyclosome

A subunit of the anaphase-promoting complex whose primary function is to provide structural support for the catalytic and substrate-recognition modules of the complex. Apc4, along with Apc5, tethers the tetratricopeptide-coactivator binding subcomplex to the main structural subunit, Apc1.


A woman who is head of a house of certain orders of nuns, and who is next in rank below an abbess.


Picornaviruses Senecavirus Sicinivirus Tremovirus Pasivirus Avihepatovirus Picornaviridae Sapelovirus Rosavirus

A family of small RNA viruses comprising some important pathogens of humans and animals. Transmission usually occurs mechanically. There are nine genera: APHTHOVIRUS; CARDIOVIRUS; ENTEROVIRUS; ERBOVIRUS; HEPATOVIRUS; KOBUVIRUS; PARECHOVIRUS; RHINOVIRUS; and TESCHOVIRUS.


General Practice, Dental
Practice, Dental General
Dental General Practice
Dental General Practices
General Practices, Dental
Practices, Dental General

Nonspecialized dental practice which is concerned with providing primary and continuing dental care.


Bilateral Synchronous Inferior Petrosal Sinus Sampling

Sampling of blood levels of the adrenocorticotropic hormone (ACTH) by withdrawal of blood from the inferior petrosal sinus. The inferior petrosal sinus arises from the cavernous sinus and runs to the internal jugular vein. Sampling of blood at this level is a valuable tool in the differential diagnosis of Cushing disease, Cushing syndrome, and other adrenocortical diseases.


Hospital Unit Dose Drug Distribution Systems

Overall systems, traditional or automated, to provide medication to patients in hospitals. Elements of the system are: handling the physician's order, transcription of the order by nurse and/or pharmacist, filling the medication order, transfer to the nursing unit, and administration to the patient.


L-Tryptophan Aminotransferase
Tryptophan Transaminase
Tryptophan Aminotransferase

A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer amino group from L-TRYPTOPHAN to 2-oxoglutarate in order to generate indolepyruvate and L-GLUTAMATE.


Mycobacterium duvalii
Mycobacterium terrae
Mycobacterium szulgai
Mycobacterium flavescens
Mycobacterium obuense
Mycobacterium, Atypical
Nontuberculous Mycobacterium
Atypical Mycobacterium
Mycobacterium gordonae
Non-Tuberculous Mycobacteria
Mycobacterium gilvum
Atypical Mycobacteria
Mycobacteria, Atypical
Nontuberculous Mycobacteria
Tuberculoid Bacillus

So-called atypical species of the genus MYCOBACTERIUM that do not cause tuberculosis. They are also called tuberculoid bacilli, i.e.: M. abscessus, M. buruli, M. chelonae, M. duvalii, M. flavescens, M. fortuitum, M. gilvum, M. gordonae, M. intracellulare (see MYCOBACTERIUM AVIUM COMPLEX;), M. kansasii, M. marinum, M. obuense, M. scrofulaceum, M. szulgai, M. terrae, M. ulcerans, M. xenopi.


Protein Conformation, alpha-Helical
alpha-Helical Structures
alpha-Helix
alpha-Helical Conformation, Protein
alpha-Helical Protein Conformation
alpha-Helices

A secondary structure of proteins that is a right-handed helix or coil, where each amino (N-H) group of the peptide backbone contributes a hydrogen bond to the carbonyl(C=O) group of the amino acid four residues N-terminal to it (n-4). It is the most common type of secondary structure.


HLA Class II Histocompatibility Antigen, DQ beta Chains

Transmembrane proteins that form the beta subunits of the HLA-DQ antigens.


RUNX1 Translocation Partner 1 Protein
Eight Twenty One Protein
RUNX1T1 Protein

A transcriptional co-repressor that contains a MYND-type zinc finger (MYND DOMAIN) at its C-terminal and functions as a homo-oligomer. It associates with DNA-binding transcription factors, other repressor proteins, and HISTONE ACETYLTRANSFERASES to repress expression of genes involved in cell growth and differentiation such as MATRIX METALLOPROTEINASE 7 and TCF12. A CHROMOSOMAL TRANSLOCATION involving the RUNX1T1 and CORE BINDING FACTOR ALPHA 2 SUBUNIT (RUNX1) genes frequently occurs in cells of leukemia patients; the resulting fusion protein (AML1-ETO or RUNX1-RUNX1T1) plays a critical role in leukemogenesis.


Thoracoabdominal Syndrome
Pentalogy of Cantrell
Cantrell Haller Ravitch syndrome
Cantrell's Pentalogy
Cantrell Pentalogy

Rare congenital deformity syndrome characterized by a combination of five anomalies as a result of neural tube defect. The five anomalies are a midline supraumbilical abdominal wall defect (e.g., OMPHALOCELE), a lower STERNUM defect, a congenital intracardiac defect, an anterior DIAPHRAGM defect, and a diaphragmatic PERICARDIUM defect (e.g., PERICARDIAL EFFUSION). Variants with incomplete and variable combinations of the defects are known. ECTOPIA CORDIS; CLEFT LIP; and CLEFT PALATE are often associated with the syndrome.


Diet, Reducing
Weight Reduction Diet
Weight Loss Diet

A diet designed to cause an individual to lose weight.


Maxillary Expansion
Palatal Expansion Technic
Palatal Expansion Technique

An orthodontic method used for correcting narrow or collapsed maxillary arches and functional cross-bite. (From Jablonski's Dictionary of Dentistry),


Influenza A Virus, H5N1 Subtype
H5N1 Virus

A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 5 and neuraminidase 1. The H5N1 subtype, frequently referred to as the bird flu virus, is endemic in wild birds and very contagious among both domestic (POULTRY) and wild birds. It does not usually infect humans, but some cases have been reported.


The family of civets which are small and medium-sized Old World carnivores, often striped or spotted.


Adrenergic beta-3 Receptor
Adrenergic Receptors, beta-3
Receptors, Adrenergic, beta-3
Adrenergic beta-3 Receptors
Receptors, beta-3 Adrenergic
beta3 Adrenoreceptor
beta-3 Adrenergic Receptors
Receptor, Adrenergic beta-3

A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The beta-3 adrenergic receptors are the predominant beta-adrenergic receptor type expressed in white and brown ADIPOCYTES and are involved in modulating ENERGY METABOLISM and THERMOGENESIS.


Hospital, Rehabilitation
Hospitals, Rehabilitation

Free standing rehabilitation hospitals and rehabilitation units in acute care hospitals.  They provide an intensive inpatient rehabilitation program.


Malonyl Coenzyme A-Acyl Carrier Protein Transacylase

This enzyme catalyzes the transacylation of malonate from MALONYL CoA to activated holo-ACP, to generate malonyl-(acyl-carrier protein), which is an elongation substrate in FATTY ACIDS biosynthesis. It is an essential enzyme in the biosynthesis of FATTY ACIDS in all BACTERIA.


Sphenocleales Cestrales Solanales Convolvulales Cuscutales Nolanales Hydroleales

An order of flowering plants comprising tropical and temperate species, major crop plants such as potatoes, tomatoes, bell peppers, eggplants, tobacco, and the garden petunia. Its largest family is the SOLANACEAE.


Encephalitozoon cuniculi
Nosema cuniculi

A species of parasitic FUNGI. This intracellular parasite is found in the BRAIN; HEART; and KIDNEYS of several MAMMALS. Transmission is probably by ingestion of the spores (SPORES, FUNGAL).


Monoferric Transferrins
tau-Transferrin
Transferrin B
Isotransferrin
beta-1 Metal-Binding Globulin
Transferrin C
Serotransferrin
Siderophilin
beta 2-Transferrin
Transferrin

An iron-binding beta1-globulin that is synthesized in the LIVER and secreted into the blood. It plays a central role in the transport of IRON throughout the circulation. A variety of transferrin isoforms exist in humans, including some that are considered markers for specific disease states.


The number of copies of a given gene present in the cell of an organism. An increase in gene dosage (by GENE DUPLICATION for example) can result in higher levels of gene product formation. GENE DOSAGE COMPENSATION mechanisms result in adjustments to the level GENE EXPRESSION when there are changes or differences in gene dosage.


Dental Clasps
Dental Clasp
Denture Clasps
Clasp, Dental
Clasps, Dental

Metal devices for fastening together two or more parts of dental prostheses for stabilizing or retaining them by attachment to abutment teeth. For a precision attachment for a partial denture DENTURE PRECISION ATTACHMENT is available.


Toll-Like Receptor Signal Adaptor Protein MyD88

An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.


Smad9 Protein
Madh9 Protein
Smad8 Protein

A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS and regulates BONE MORPHOGENETIC PROTEIN signaling.


Benzaldehyde Dehydrogenase (NADP+)
Benzaldehyde Dehydrogenase (NADP)
NADP-Linked Benzaldehyde Dehydrogenase

An NADP+ dependent enzyme that catalyzes the oxidation of benzaldehyde to BENZOIC ACID. It also plays a role in the degradation of TOLUENE and XYLENE.


The systematic surveying, mapping, charting, and description of specific geographical sites, with reference to the physical features that were presumed to influence health and disease. Medical topography should be differentiated from EPIDEMIOLOGY in that the former emphasizes geography whereas the latter emphasizes disease outbreaks.


State of the body in relation to the consumption and utilization of nutrients.


Leukemia-Lymphoma Virus I Antigens, Human T-Cell

Leukemia Lymphoma Virus I Antigens, Human T Cell

Antigens associated with HUMAN T-LYMPHOTROPIC VIRUS 1.


Schizophrenia
Schizophrenic Disorders
Dementia Praecox

A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.


Antineutrophil Cytoplasmic Antibodies
p-ANCA
Anti-Neutrophil Cytoplasmic Antibody
Anti-Neutrophil Cytoplasmic Antibodies
Antineutrophil Cytoplasmic Antibody
c-ANCA
ANCA
Antibodies, Antineutrophil Cytoplasmic

Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for GRANULOMATOSIS WITH POLYANGIITIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.


Lichen Sclerosus et Atrophicus
Lichen Sclerosus
Lichen Sclerosis
Lichen Sclerosis et Atrophicus

A chronic inflammatory mucocutaneous disease usually affecting the female genitalia (VULVAR LICHEN SCLEROSUS) and BALANITIS XEROTICA OBLITERANS in males. It is also called white spot disease and Csillag's disease.


Foscarnet Sodium
Phosphonoformate
Trisodium Phosphonoformate
Foscarnet Manganese (2+) (2:3) Salt
Foscarnet Magnesium (2:3) Salt
Foscarnet Sodium Hexahydrate
Foscarnet
Foscarnet Disodium Salt
Phosphonoformic Acid
Foscavir
Foscarnet Tripotassium Salt
Foscarnet Trisodium Salt
Foscarnet Calcium (2:3) Salt
Foscarnet Barium (2:3) Salt
Foscarnet Trilithium Salt

An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.


Alcoholism
Alcohol Abuse
Alcohol Addiction
Alcoholic Intoxication, Chronic
Alcohol Use Disorder
Alcohol Dependence

A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)


Lentiviruses, Feline
Feline Lentiviruses

A subgenus of LENTIVIRUS comprising viruses that produce multi-organ disease with long incubation periods in cats.


Reperfusion Injury, Myocardial
Myocardial Reperfusion Injury
Injury, Myocardial Reperfusion
Myocardial Ischemic Reperfusion Injury

Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.


ATF1 Transcription Factor
Activating Transcription Factor-1
Activating Transcription Factor 1

An activating transcription factor that regulates expression of a variety of genes including C-JUN GENES and TRANSFORMING GROWTH FACTOR BETA2.


Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.


Enzymes that hydrolyze O-glucosyl-compounds. (Enzyme Nomenclature, 1992) EC 3.2.1.-.


Adnexitis
Pelvic Inflammatory Disease
Inflammatory Pelvic Disease
Inflammatory Disease, Pelvic
Pelvic Disease, Inflammatory

Inflammation of the uterine appendages (ADNEXA UTERI) including infection of the FALLOPIAN TUBES (SALPINGITIS), the ovaries (OOPHORITIS), or the supporting ligaments (PARAMETRITIS).


Fibroblast Growth Factor
DNA Synthesis Factor
Fibroblast Growth Regulatory Factor
Fibroblast Growth Factors

A family of small polypeptide growth factors that share several common features including a strong affinity for HEPARIN, and a central barrel-shaped core region of 140 amino acids that is highly homologous between family members. Although originally studied as proteins that stimulate the growth of fibroblasts this distinction is no longer a requirement for membership in the fibroblast growth factor family.


Wooley monkey sarcoma virus
Sarcoma Virus, Woolly Monkey
Simian Sarcoma Viruses
Woolly Monkey Virus
Sarcoma Viruses, Simian

A species of GAMMARETROVIRUS producing tumors in primates. Originally isolated from a fibrosarcoma in a woolly monkey, WMSV is a replication-defective v-onc virus which carries the sis oncogene. In order to propagate, WMSV requires a replication-competent helper virus.


A genus of cone-shaped marine snails in the family Conidae, class GASTROPODA. It comprises more than 600 species, many containing unique venoms (CONUS VENOMS) with which they immobilize their prey.


An enzyme that catalyzes the conversion of urate and unidentified products. It is a copper protein. The initial products decompose to form allantoin. EC 1.7.3.3.


Epithelium, Corneal
Corneal Epithelium, Anterior
Corneal Epithelium
Epithelium, Anterior Corneal
Anterior Corneal Epithelium

Stratified squamous epithelium that covers the outer surface of the CORNEA. It is smooth and contains many free nerve endings.


One of two ganglionated neural networks which together form the ENTERIC NERVOUS SYSTEM. The myenteric (Auerbach's) plexus is located between the longitudinal and circular muscle layers of the gut. Its neurons project to the circular muscle, to other myenteric ganglia, to submucosal ganglia, or directly to the epithelium, and play an important role in regulating and patterning gut motility. (From FASEB J 1989;3:127-38)


Learning Healthcare System
Learning Health Community
Learning Health System

Community in which where health care providers, researchers, and administrators engage area residents in an on-going communication to establish trust, remain healthy, and improve health literacy before treatment is needed.


Esophageal Sphincter, Lower
Gastroesophageal Sphincter
Lower Esophageal Sphincter

The physiologic or functional barrier to GASTROESOPHAGEAL REFLUX at the esophagogastric junction. Sphincteric muscles remain tonically contracted during the resting state and form the high-pressure zone separating the lumen of the ESOPHAGUS from that of the STOMACH. (Haubrich et al, Bockus Gastroenterology, 5th ed., pp399, 415)


A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)


Parasitic Diseases, Animal
Parasitic Infections, Animal


Serpin A7
Thyropexin
Thyroxine-Binding Globulin

A thyroid hormone transport protein found in serum. It binds about 75% of circulating THYROXINE and 70% of circulating TRIIODOTHYRONINE.


Guava, Pineapple
Pineapple Guava
Feijoa
Guavasteen

A plant genus of the family MYRTACEAE that is cultivated for the edible fruit, which is different from the ordinary guava (PSIDIUM).


Small Myelin-Associated Glycoprotein Isoform

Large Myelin-Associated Glycoprotein Isoform

A myelin protein found in the periaxonal membrane of both the central and peripheral nervous systems myelin sheaths. It binds to cells surface receptors found on AXONS and may regulate cellular interactions between MYELIN and AXONS.


Isoimmunization, Rhesus
Rh Isoimmunization
Rh Sensitization

The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.


Within a eukaryotic cell, a membrane-limited body which contains chromosomes and one or more nucleoli (CELL NUCLEOLUS). The nuclear membrane consists of a double unit-type membrane which is perforated by a number of pores; the outermost membrane is continuous with the ENDOPLASMIC RETICULUM. A cell may contain more than one nucleus. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)


Killer Cell Immunoglobulin-Like Receptor 3DL1

A KIR receptor that has specificity for HLA-B ANTIGENS. It is an inhibitory receptor that contains D0, D1, and D2 extracellular immunoglobulin-like domains and a long cytoplasmic tail.


Lactotrophs
Pituitary Prolactin-Secreting Cells
Pituitary Prolactin Cells

Anterior pituitary cells that produce PROLACTIN.


5-Hydroxytryptamine Agonists
5-HT Agonist
Serotonin Receptor Agonists
Serotonin Agonist
5-HT Agonists
Serotonin Agonists
5-Hydroxytrytamine Agonist
Serotonin Receptor Agonist
Receptor Agonists, Serotonin
Serotonergic Agonists
Serotonergic Agonist

Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.


Gene Products, Algal
Algal Peptides
Algal Gene Products
Algal Proteins
Algal Gene Proteins


Antennal Sensilla
Antennal Sensillum
Sensilla
Olfactory Sensilla
Setae
Sensillum

Collective name for a group of external MECHANORECEPTORS and CHEMORECEPTORS manifesting as sensory structures in ARTHROPODS. They include cuticular projections (setae, hairs, bristles), pores, and slits.


Signaling Lymphocytic Activation Molecule Receptors

Signaling Lymphocytic Activation Molecule Family Receptors

Signaling Lymphocytic Activation Molecules

Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation.


Fulminant Hepatic Failure with Cerebral Edema

A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)


Four carbon unsaturated hydrocarbons containing two double bonds.


Oligodendrocyte Precursor Cells
Preoligodendrocytes
Oligodendrocyte Progenitors
Pre-Oligodendrocytes
Oligodendrocyte Progenitor Cells
Oligodendrocyte Precursors

Neuroglial cells that first appear during mid-embryogenesis in the central nervous system of mammals and give rise to OLIGODENDROCYTES. Mitotically-active populations remain through late adulthood and are capable of regenerating MYELIN lost to disease or injury.


DIARRHEA occurring in infants from newborn to 24-months old.


Protein Tyrosine Phosphatase, Non-Receptor Type 1

A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.


The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.


Copper Influx Transporter
Copper Transporter 1
SLC31A1 Protein
COPT1 Protein
Copper Transport Protein 1

A high-affinity, saturable copper transporter of the PLASMA MEMBRANE that functions in the absorption of dietary copper.


Blood Coagulation Factor V, Activated
Factor 5A
Factor Va
Factor Five A
Coagulation Factor Va
Factor V, Activated

Activated form of factor V. It is an essential cofactor for the activation of prothrombin catalyzed by factor Xa.


Propylene Glycol, (R)-Isomer
Propan-1,2-Diol
Propylene Glycol, (+-)-Isomer
1,2-Propanediol
Propylene Glycol
Propylene Glycol Monohydrate
Propylene Glycol Sodium Salt
Propylene Glycol, (S)-Isomer

A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.


Receptors, Insulin-Like Growth Factors
Somatomedin Receptor
Insulin-Like Growth Factor Receptors
Somatomedin Receptors
Insulin-Like Growth Factor Receptor
Receptors, Somatomedin

Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.


Blocking Agents, Ganglionic
Ganglioplegic Agents
Ganglionic Blockers
Ganglionic Blocking Agents
Ganglionic Blockaders

Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.


The scientific study of inherited human variation.


A trisaccharide occurring in Australian manna (from Eucalyptus spp, Myrtaceae) and in cottonseed meal.


Sex Reassignment Procedures
Gender Reassignment Procedures
Gender Change Procedures
Gender Confirmation Procedures
Sex Change Procedures

Clinical treatments used to change the physiological sexual characteristics of an individual.


Bispecific Monoclonal Antibodies
Bispecific Antibodies
Bifunctional Antibodies
Antibodies, Bispecific

Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIGENIC DETERMINANTS. They are artificial antibodies produced by chemical crosslinking, fusion of HYBRIDOMA cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabeled haptens, and effector cells to diseased tissue, primarily tumors.


Nonoxynol-9
Nonoxynols
Nonoxynol, 4-Sulfate, Ammonium Salt
Advantage-S
Nonoxynol
Emulgin 913
Patentex Oval
Nonoxinols
Nonylphenoxypolyethoxyethanol
Nonylphenoxypolyethoxyethanols
Emulgen 911
Delfen Cream
Nonoxynol, 1(4)-Sulfate, Sodium Salt
Nonoxinol

A spermicidal contraceptive vaginal gel that contains nonoxynol-9 (N-9), available without prescription


Calcium Binding Proteins
Calcium-Binding Proteins

Proteins to which calcium ions are bound. They can act as transport proteins, regulator proteins, or activator proteins. They typically contain EF HAND MOTIFS.


A quiescent state of cells during G1 PHASE.


Denture, Partial, Fixed
Pontic
Fixed Bridge
Fixed Partial Denture

A partial denture attached to prepared natural teeth, roots, or implants by cementation.


HBeAg
HBe Ag-1
Hepatitis B e Antigens
HBe Ag-2
e Antigens
Hepatitis Be Antigens

A closely related group of antigens found in the plasma only during the infective phase of hepatitis B or in virulent chronic hepatitis B, probably indicating active virus replication; there are three subtypes which may exist in a complex with immunoglobulins G.


The aorta from the DIAPHRAGM to the bifurcation into the right and left common iliac arteries.


Experimental Psychology
Psychology, Experimental

The branch of psychology which seeks to learn more about the fundamental causes of behavior by studying various psychologic phenomena in controlled experimental situations.


Chloromercuribenzenesulfonate
p-Chloromercuriphenylsulphonate
PCMBS
4-Chloromercuribenzenesulfonate
Chloromercuribenzene-p-sulphonic Acid
Chloromercuriphenylsulfonate
PCMPS

A cytotoxic sulfhydryl reagent that inhibits several subcellular metabolic systems and is used as a tool in cellular physiology.


One of two types of muscle in the body, characterized by the array of bands observed under microscope. Striated muscles can be divided into two subtypes: the CARDIAC MUSCLE and the SKELETAL MUSCLE.


T-Cell Leukemia
T Lymphocytic Leukemia
Leukemia, Lymphocytic, T-Cell
T-Lymphocytic Leukemia
Leukemia, T-Cell
Leukemia, Lymphocytic, T Cell
Lymphocytic Leukemia, T-Cell

A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood.


A common parasite of humans in the moist tropics and subtropics. These organisms attach to villi in the small intestine and suck blood causing diarrhea, anorexia, and anemia.


The use of freezing as a special surgical technique to destroy or excise tissue.


Behavioral Economics
Economics, Behavioral

The combined discipline of psychology and economics that investigates what happens in markets in which some of the agents display human limitations and complications.


Phosphocreatine
Phosphocreatine, Disodium Salt
Creatine Phosphate
Neoton
Phosphorylcreatine

An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996)


Plant Tumors
Plant Galls
Crown Gall
Galls, Plant

A localized proliferation of plant tissue forming a swelling or outgrowth, commonly with a characteristic shape and unlike any organ of the normal plant. Plant tumors or galls usually form in response to the action of a pathogen or a pest. (Holliday, P., A Dictionary of Plant Pathology, 1989, p330)


Glia
Neuroglia
Glial Cells
Neuroglial Cells

The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the BLOOD-BRAIN BARRIER and BLOOD-RETINAL BARRIER, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.


Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.


Photokymography
Kymography, Radiographic
Roentgenkymography
Electrokymography
Radiographic Kymography

Radiographic technique combining a photoelectric recording system with fluoroscopy. It is used especially with electrocardiography to study heart motion.


Tuberous Sclerosis 2 Protein
Tuberous Sclerosis Complex 2 Protein
Tuberin

An intracellular signaling and tumor suppressor protein that forms a complex with TUBEROUS SCLEROSIS COMPLEX 1 PROTEIN (TSC1) and other signaling factors to negatively regulate MTORC1 and affect cell growth and proliferation. It can also function as GTPASE-ACTIVATING PROTEIN (GAP) for RHEB GTPASE to activate mTORC1 independent of its role in the complex. Structurally, it interacts with TSC1 through its N-terminus, which also contains a leucine zipper and coiled-coil region. It also has multiple phosphorylation sites for different cell signaling kinases, a central coiled-coil region, a C-terminal GAP domain and CALMODULIN binding domain. Mutations in the TSC2 gene are associated with TUBEROUS SCLEROSIS.


Health care provided during a transition to a different mode of care (e.g., TRANSITION TO ADULT CARE).


Galanin Receptor
Galanin Receptors
Receptors, Galanin

A family of G-protein-coupled receptors that are specific for GALANIN and galanin peptides. They are generally considered to be coupled to the GI, INHIBITORY G-PROTEIN to meditate the neurological effects of galanin. Several subtypes of galanin receptors occur with differing specificities for the full length galanin, galanin peptide fragments, and galanin-like peptide.


Reimbursement, Disproportionate Share
Disproportionate Share Reimbursement
Disproportionate Reimbursement

Payments that include adjustments to reflect the costs of uncompensated care and higher costs for inpatient care for certain populations receiving mandated services. MEDICARE and MEDICAID include provisions for this type of reimbursement.


Adenylyl Cyclase Inhibitors
Adenylate Cyclase Inhibitors

Compounds that bind to and inhibit the action of ADENYLYL CYCLASES.


An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.


Anti-Australia Antigens
Anti-HBAg
Hepatitis B Antibodies
Anti HBAg
Anti-Hepatitis B Antigens
Hepatitis B Virus Antibodies

Antibodies to the HEPATITIS B ANTIGENS, including antibodies to the surface (Australia) and core of the Dane particle and those to the "e" antigens.


Osteogenesis, Distraction
Callotasis
Distraction Osteogenesis

Bone lengthening by gradual mechanical distraction. An external fixation device produces the distraction across the bone plate. The technique was originally applied to long bones but in recent years the method has been adapted for use with mandibular implants in maxillofacial surgery.


Neutron Capturing Therapy
Therapy, Neutron Capture
Neutron Capture Therapy

A technique for the treatment of neoplasms in which an isotope is introduced into target cells followed by irradiation with thermal neutrons.


SARS (Severe Acute Respiratory Syndrome)

A viral disorder characterized by high FEVER, dry COUGH, shortness of breath (DYSPNEA) or breathing difficulties, and atypical PNEUMONIA. A virus in the genus CORONAVIRUS is the suspected agent.


Biglycan
Proteoglycan S1
Bone Proteoglycan I

A small leucine-rich proteoglycan found in a variety of tissues including CAPILLARY ENDOTHELIUM; SKELETAL MUSCLE; CARTILAGE; BONE; and TENDONS. The protein contains two glycosaminoglycan chains and is similar in structure to DECORIN.


Enoyl-CoA Hydratase
Enoyl Hydrase
beta-Hydroxyacyl-CoA Dehydrases
Enoyl CoA Hydratases
beta-Hydroxyacyl Dehydratases
3-Hydroxyacyl Dehydratases
3-Hydroxyacyl CoA Hydrolyases
trans-2-Enoyl-Coenzyme A Hydratase
Crotonase

An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.


Pluripotent Stem Cells
Stem Cells, Pluripotent

Cells that can give rise to cells of the three different GERM LAYERS.


Complement
Complement Protein
Complement Proteins
Complement System Proteins
Hemolytic Complement

Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY).


Supravalvular Aortic Stenosis
Stenosis, Supravalvular Aortic
Stenosis, Aortic Supravalvular
Supravalvular Stenosis, Aortic
Supravalvar Aortic Stenosis
Aortic Stenosis, Supravalvular
Aortic Supravalvular Stenosis

A pathological constriction occurring in the region above the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.


Mannosides formed by the reaction of the hydroxyl group on the anomeric carbon atom of mannose with methyl alcohol. They include both alpha- and beta-methylmannosides.


Mitogen-Activated Protein Kinase Kinase 4

SAP Kinase-Extracellular Signal-Regulated Kinase Kinase 1

Stress-Activated Protein Kinase Kinase 1

A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES and the RETINOID X RECEPTORS. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to cellular stress.


Complement C5 Convertase, Classical Pathway

A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEMENT 5B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of CLASSICAL PATHWAY C3 CONVERTASE (C4b2a) with an additional COMPLEMENT C3B, or C4b2a3b.


Shipping Fever Virus
Bovine parainfluenza virus 3
Parainfluenza Virus 3, Bovine

A species of RESPIROVIRUS, subfamily PARAMYXOVIRINAE, most often seen in conjunction with a secondary infection of MANNHEIMIA HAEMOLYTICA resulting in pneumonic pasteurellosis (PASTEURELLOSIS, PNEUMONIC).


High-Temperature Requirement A Serine Peptidase 1

A secreted serine protease that contains a Kazal domain-like region and a C-terminal PDZ domain. It has a broad range of targets that include EXTRACELLULAR MATRIX PROTEINS; PROTEOGLYCANS; and INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS. Mutations in the HTRA1 gene are associated with AGE-RELATED MACULAR DEGENERATION 7 and Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL).


Thymidylate Synthase
Thymidylate Synthetase

An enzyme of the transferase class that catalyzes the reaction 5,10-methylenetetrahydrofolate and dUMP to dihydrofolate and dTMP in the synthesis of thymidine triphosphate. (From Dorland, 27th ed) EC 2.1.1.45.


Management review designed to evaluate efficiency and to identify areas in need of management improvement within the institution in order to ensure effectiveness in meeting organizational goals.


Receptors, IL-6
Interleukin-6 Receptors
IL6 Receptors
IL-6 Receptor
Receptors, Interleukin-6
IL6 Receptor
Interleukin 6 Receptor
IL-6 Receptors

Cell surface receptors that are specific for INTERLEUKIN-6. They are present on T-LYMPHOCYTES, mitogen-activated B-LYMPHOCYTES, and peripheral MONOCYTES. The receptors are heterodimers of the INTERLEUKIN-6 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130.


Reoviruses, Aquatic
Respiratory Enteric Orphan Viruses
Reoviridae
Aquareovirus
Cytoplasmic Polyhedrosis Viruses
Idnoreovirus
Fijivirus
Phytoreovirus
Mycoreovirus
Seadornavirus
Cypovirus
Oryzavirus

A family of unenveloped RNA viruses with cubic symmetry. The twelve genera include ORTHOREOVIRUS; ORBIVIRUS; COLTIVIRUS; ROTAVIRUS; Aquareovirus, Cypovirus, Phytoreovirus, Fijivirus, Seadornavirus, Idnoreovirus, Mycoreovirus, and Oryzavirus.


Luciola Photinus Firefly Lampyridae Fireflies

The family Lampyidae, which are bioluminescent BEETLES. They contain FIREFLY LUCIFERIN and LUCIFERASES. Oxidation of firefly luciferin results in luminescence.


A tetrazole derivative and ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER that is used to treat HYPERTENSION.


Pathological Processes
Pathologic Processes
Processes, Pathologic

The abnormal mechanisms and forms involved in the dysfunctions of tissues and organs.


Carnitine-Acetylcarnitine Translocase
Carnitine-Acylcarnitine Translocase
Carnitine Acyltransferases
Acylcarnitine Translocase
Carnitine Translocase

Acyltransferases in the inner mitochondrial membrane that catalyze the reversible transfer of acyl groups from acyl-CoA to L-carnitine and thereby mediate the transport of activated fatty acids through that membrane. EC 2.3.1.


A type of pregnancy in which EMBRYO IMPLANTATION occurs in an OVARY instead of in the uterine cavity.


Membrane-Type Matrix Metalloproteinase 1

Membrane-Type 1 Matrix Metalloproteinase

A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15.


Rhamnose
Rhamnose, L-Isomer
Deoxymannose

A methylpentose whose L- isomer is found naturally in many plant glycosides and some gram-negative bacterial lipopolysaccharides.


Phospholipases A1
Phospholipase A1
Phosphatidate 1-Acylhydrolase
Lecithinase A1

A phospholipase that hydrolyzes the acyl group attached to the 1-position of PHOSPHOGLYCERIDES.


A genus of flowering plants in the family of mallows (MALVACEAE). Their common name is fanpetals.


Prenatal Programming
Embryo and Fetal Development
Embryonic and Fetal Development

Permanent alteration of tissue structures and functions as a result of prenatal environment, either positive or negative.


Prostaglandin Endoperoxide Synthase Inhibitors

Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.


Interleukin-7 Receptor alpha Subunit
CD127 Antigens
CD127 Antigen
Antigens, CD127

A low affinity interleukin-7 receptor subunit that combines with the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT to form a high affinity receptor for INTERLEUKIN-7.


A beak-like bone projection located at the lateral end of the superior anterior border of the SCAPULA.


Deanol
Tonibral
Dimethylaminoethanol
N,N-Dimethyl-2-hydroxyethylamine
Dimethylethanolamine
Demanyl
Demanol
Astyl
Deanol Bisorcate
N,N-Dimethylethanolamine

An antidepressive agent that has also been used in the treatment of movement disorders. The mechanism of action is not well understood.


Vitamin B Deficiency
Deficiency, Vitamin B

A condition due to deficiency in any member of the VITAMIN B COMPLEX. These B vitamins are water-soluble and must be obtained from the diet because they are easily lost in the urine. Unlike the lipid-soluble vitamins, they cannot be stored in the body fat.


Epithelial Sodium Channel Activators
Epithelial Sodium Channel Stimulators
Epithelial Sodium Channel Agonists

Compounds that either stimulate the opening or prevent closure of EPITHELIAL SODIUM ION CHANNELS.


Compounds or factors that act on a specific enzyme to increase its activity.


Technique involving the diffusion of antigen or antibody through a semisolid medium, usually agar or agarose gel, with the result being a precipitin reaction.


An order of New World mammals characterized by the absence of incisors and canines from among their teeth, and comprising the ARMADILLOS, the SLOTHS, and the anteaters. The order is distinguished from all others by what are known as xenarthrous vertebrae (xenos, strange; arthron, joint): there are secondary, and sometimes even more, articulations between the vertebrae of the lumbar series. The order was formerly called Edentata. (From Random House Unabridged Dictionary, 2d ed; Walker's Mammals of the World, 5th ed, vol. I, p515)


Venoms produced by FISHES, including SHARKS and sting rays, usually delivered by spines. They contain various substances, including very labile toxins that affect the HEART specifically and all MUSCLES generally.


Bronchial Neoplasms
Neoplasms, Bronchial


Nuclear Receptor Subfamily 2, Group C, Member 1

A DNA-binding orphan nuclear receptor that has specificity for directly repeated (DR) AGGTCA sequences. It binds DNA as either as a homodimer or as a heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 2. The protein was originally identified as a PROSTATE-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.


A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these compounds. These are similar to CARBAZOLES which are benzo-indoles.


Thiazide diuretic also used as an antihypertensive agent.


Haemophilus segnis
Aggregatibacter segnis

A species of Gram-negative, facultatively anaerobic pleomorphic rod-shaped often filamentous bacteria in the genus of AGGREGATIBACTER found in the oral cavity. It is associated with DENTAL PLAQUE; and BACTERIAL ENDOCARDITIS.


Diacetyl Dimethylglyoxal 2,3-Butanedione Dimethyldiketone Diketobutane Biacetyl

Carrier of aroma of butter, vinegar, coffee, and other foods.


Pre-B Cell Receptor
Pre-B Cell Receptors

Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU IMMUNOGLOBULIN HEAVY CHAINS in complex with SURROGATE LIGHT CHAINS instead of conventional IMMUNOGLOBULIN LIGHT CHAINS. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the pre-B cell receptors is an important checkpoint in the development of mature B cells.


Ribonucleoprotein Domain Proteins
RNA Recognition Motif Proteins
RNA-Binding Domain Proteins
RRM Proteins

A family of RNA-BINDING PROTEINS that contain an RNA RECOGNITION MOTIF and two ribonucleoprotein (RNP) domains which bind RNA, in addition to other domains that allow for high affinity binding, sequence specificity, and protein interactions. Examples of RNA recognition motif proteins include HETEROGENEOUS NUCLEAR RIBONUCLEARPROTEINS (hnRNP) and EMBRYONIC LETHAL ABNORMAL-VISION (ELAV) proteins.


A subgroup of TRP cation channels that are widely expressed in various cell types. Defects are associated with POLYCYSTIC KIDNEY DISEASES.


Albright Hereditary Osteodystrophy without Multiple Hormone Resistance

A form of PSEUDOHYPOPARATHYROIDISM characterized by the same features except for the abnormal response to hormones such as PARATHYROID HORMONE. It is associated with paternally inherited mutant alleles of the ALPHA CHAIN OF STIMULATORY G PROTEIN.


Tiapride
Tiapride Monohydrochloride
Tiaprizal
Equilium
FLO-1347
Tiapride Hydrochloride
Tiapridex
Tiapridal

A benzamide derivative that is used as a dopamine antagonist.


A species of HAEMOPHILUS that appears to be the pathogen or causative agent of the sexually transmitted disease, CHANCROID.


4-(2-Aminoethyl)-1,2-benzenediol
Hydroxytyramine
Dopamine
3,4-Dihydroxyphenethylamine
Dopamine Hydrochloride
Intropin

One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.


Single-Chain Urokinase-Type Plasminogen Activator

A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.


Toxic antibiotic of the mitomycin group, obtained from MITOMYCIN and also from Streptomyces ardus and other species. It is proposed as an antineoplastic agent, with some antibiotic properties.


Corpus Callosum
Neocortical Commissure
Interhemispheric Commissure

Broad plate of dense myelinated fibers that reciprocally interconnect regions of the cortex in all lobes with corresponding regions of the opposite hemisphere. The corpus callosum is located deep in the longitudinal fissure.


DNA sequences that form the coding region for proteins associated with the viral core in retroviruses. gag is short for group-specific antigen.


Nitrogenase
Dinitrogenase
Vanadium Nitrogenase

An enzyme system that catalyzes the fixing of nitrogen in soil bacteria and blue-green algae (CYANOBACTERIA). EC 1.18.6.1.


Cytochrome P-450 CYP2D6 Inhibitors
P450 CYP2D6 Inhibitors
CYP2D6 Inhibitors

Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP2D6.


Crimean-Congo hemorrhagic fever virus
Hemorrhagic Fever Virus, Crimean-Congo
Congo Virus
Hemorrhagic Fever Virus, Crimean

A species of NAIROVIRUS of the family BUNYAVIRIDAE. It is primarily transmitted by ticks and causes a severe, often fatal disease in humans.


A sulfhydryl proteinase with cysteine at the active site from ficus latex. Preferential cleavage is at tyrosine and phenylalanine residues. EC 3.4.22.3.


Choroid Plexus
Chorioid Plexus
Plexus Choroideus

A villous structure of tangled masses of BLOOD VESSELS contained within the third, lateral, and fourth ventricles of the BRAIN. It regulates part of the production and composition of CEREBROSPINAL FLUID.


Obstructive Pulmonary Diseases
Lung Diseases, Obstructive
Obstructive Lung Diseases

Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.


Ectopic Heartbeats
Premature Cardiac Complex
Cardiac Complex, Premature
Cardiac Complexes, Premature
Extrasystole
Premature Beats
Extrasystoles
Premature Cardiac Complexes

A group of cardiac arrhythmias in which the cardiac contractions are not initiated at the SINOATRIAL NODE. They include both atrial and ventricular premature beats, and are also known as extra or ectopic heartbeats. Their frequency is increased in heart diseases.


Proto-Oncogene Protein c-rel
c-rel Proteins
Proto-Oncogene Proteins rel
rel Proto-Oncogene Proteins
c-rel Protein
Proto-Oncogene Products c-rel
rel Proto-Oncogene Product p68
Proto-Oncogene Proteins c-rel
p68(c-rel)
p68 c-rel

Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.


A plant genus of the family Phrymaceae. Members contain 6-geranylflavanones and mimulone.


Selenoprotein
Selenoproteins
Selenoprotein P1

Selenoproteins are proteins that specifically incorporate SELENOCYSTEINE into their amino acid chain. Most selenoproteins are enzymes with the selenocysteine residues being responsible for their catalytic functions.


Clostridium histolyticum Collagenase
Collagenase, Microbial
Clostridiopeptidase A
Microbial Collagenase
Nucleolysin
Collagenase Clostridium histolyticum
Collalysine
Collagenase-Like Peptidase

A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.


Gold Colloid, Radioactive
Radio-Colloidal Gold

A suspension of radioactive gold particles emitting negative beta particles and gamma irradiation. It was formerly used for liver scans and irradiation treatment of some metastatic malignancies.


N-Acetylgucosamide 1-4 beta Galactosyl Transferase

An enzyme complex that catalyzes the transfer of GALACTOSE from UDP GALACTOSE to GLUCOSE, forming LACTOSE. The enzyme complex is composed of a B subunit, ALPHA-LACTALBUMIN, which changes the substrate specificity of the A subunit, N-ACETYLLACTOSAMINE SYNTHASE, from N-ACETYLGLUCOSAMINE to glucose making lactose synthesis the preferred reaction.


Systems Oriented Approach
Analysis, Systems
Systems Approach
System Dynamics Analysis
Systems Thinking
Complexity Analysis
Systems Medicine
Systems Analysis
Agent-Based Modeling

The analysis of an activity, procedure, method, technique, or business to determine what must be accomplished and how the necessary operations may best be accomplished.


Proteolipid Protein, Myelin
Folch-Lees Protein
Myelin PLP
Folch-PI Proteolipid Protein
Myelin Proteolipid Protein

A myelin protein that is the major component of the organic solvent extractable lipoprotein complexes of whole brain. It has been the subject of much study because of its unusual physical properties. It remains soluble in chloroform even after essentially all of its bound lipids have been removed. (From Siegel et al., Basic Neurochemistry, 4th ed, p122)


Pulmonary Tuberculosis
Pulmonary Tuberculoses
Tuberculosis, Pulmonary
Tuberculoses, Pulmonary
Pulmonary Phthisis
Pulmonary Consumption


Periodontal Atrophy
Gingivo-Osseous Atrophy
Atrophy of Periodontium

Degradation or wasting of the PERIODONTIUM tissues that may involve the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, or the PERIODONTAL LIGAMENT.


Sulfate Adenylyltransferase
Sulfurylase
ATP Sulfurylase

An enzyme that catalyzes the activation of sulfate ions by ATP to form adenosine-5'-phosphosulfate and pyrophosphate. This reaction constitutes the first enzymatic step in sulfate utilization following the uptake of sulfate. EC 2.7.7.4.


Desmoglein 3
Desmosomal Glycoprotein 3
Desmoglein III

A desmosomal cadherin that is an autoantigen in the acquired skin disorder PEMPHIGUS VULGARIS.


omega-Crystallins
Crystallins, omega
omega-Crystallin

A type of crystallin that has been found in the lens (LENS, CRYSTALLINE) of certain species of MOLLUSCA such as SQUID and OCTOPUS. It is an inactivated form of aldehyde dehydrogenase.


Src Homology 2 Domain-Containing Inositol Phosphatases

Phosphoinositide phosphatases that catalyze the dephosphorylation (hydrolysis) of  phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P(3)) to produce PtdIns(3,4)P(2), which negatively regulates the PI3K ( 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES) pathways. They contain an SH2 DOMAIN and STERILE ALPHA MOTIF and have important functions in regulating the immune response and other cellular processes in vertebrates.


Technic, Molecular Probe
Molecular Probe Technique
Techniques, Molecular Probe
Molecular Probe Technics
Technics, Molecular Probe
Molecular Probe Techniques
Molecular Probe Technic
Technique, Molecular Probe

The use of devices which use detector molecules to detect, investigate, or analyze other molecules, macromolecules, molecular aggregates, or organisms.


Lymphocytic Colitis
Colitis, Lymphocytic

A subtype of MICROSCOPIC COLITIS, characterized by chronic watery DIARRHEA of unknown origin, a normal COLONOSCOPY but abnormal histopathology on BIOPSY. Microscopic examination of biopsy samples taken from the COLON show infiltration of LYMPHOCYTES in the superficial EPITHELIUM and the underlying connective tissue (lamina propria).


A type of oropharyngeal airway that provides an alternative to endotracheal intubation and standard mask anesthesia in certain patients. It is introduced into the hypopharynx to form a seal around the larynx thus permitting spontaneous or positive pressure ventilation without penetration of the larynx or esophagus. It is used in place of a facemask in routine anesthesia. The advantages over standard mask anesthesia are better airway control, minimal anesthetic gas leakage, a secure airway during patient transport to the recovery area, and minimal postoperative problems.


Sodium Lauryl Sulfate
Sodium Dodecyl Sulfate
Irium

An anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.


Production or presence of gas in the gastrointestinal tract which may be expelled through the anus.


Radionuclide Tomography, Single-Photon Emission-Computed

Single-Photon Emission Computerized Tomography

Single-Photon Emission Computer-Assisted Tomography

A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.


Totipotent Stem Cells
Stem Cells, Totipotent

Single cells that have the potential to form an entire organism. They have the capacity to specialize into extraembryonic membranes and tissues, the embryo, and all postembryonic tissues and organs. (Stem Cells: A Primer [Internet]. Bethesda (MD): National Institutes of Health (US); 2000 May [cited 2002 Apr 5]. Available from: http://www.nih.gov/news/stemcell/primer.htm)


Gastric Lavage
Lavage, Gastric
Irrigation, Gastric

Medical procedure involving the emptying of contents in the stomach through the use of a tube inserted through the nose or mouth. It is performed to remove poisons or relieve pressure due to intestinal blockages or during surgery.


A monooxygenase that catalyzes the conversion of BETA-CAROTENE into two molecules of RETINAL. It was formerly characterized as EC 1.13.11.21 and EC 1.18.3.1.


A water-soluble crystalline benzene-1,3-diol (resorcinol) and its derivatives.


Database Management Systems
Management System, Data Base
Data Base Management Systems
Systems, Data Base Management
Management Systems, Data Base
System, Data Base Management

Software designed to store, manipulate, manage, and control data for specific uses.


Dinitrofluorobenzene Fluorodinitrobenzene DNFB 1-Fluoro-2,4-dinitrobenzene

Irritants and reagents for labeling terminal amino acid groups.


Nonaccidental Trauma in Children
Battered Child Syndrome

A clinical condition resulting from repeated physical and psychological injuries inflicted on a child by the parents or caregivers.


HLA Class I Histocompatibility Antigen, B-15 alpha Chain

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*15 allele family.


Spectrometry
Analysis, Spectrum
Spectroscopy
Spectrum Analysis

The use of spectrographic techniques for deriving the physical constants of materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)


Preparation of TOOTH surfaces, and of materials bonded to teeth or DENTAL IMPLANTS, with agents and methods which roughen the surface to facilitate adhesion. Agents include phosphoric or other acids (ACID ETCHING, DENTAL) and methods include LASERS.


Rochalimaea henselae
Bartonella henselae

A species of gram-negative bacteria that is the etiologic agent of bacillary angiomatosis (ANGIOMATOSIS, BACILLARY). This organism can also be a cause of CAT-SCRATCH DISEASE in immunocompetent patients.


Convalescent Hospital
Hospitals, Convalescent

Hospitals which provide care to the patient for the period following an acute illness until health is restored.


Kidney Collecting Ducts
Kidney Collecting Duct
Kidney Tubules, Collecting

Straight tubes commencing in the radiate part of the kidney cortex where they receive the curved ends of the distal convoluted tubules. In the medulla the collecting tubules of each pyramid converge to join a central tube (duct of Bellini) which opens on the summit of the papilla.


Methodologies, Computing
Computing Methodologies
High Performance Computing

Computer-assisted analysis and processing of problems in a particular area.


Online Pharmacies
Online Pharmaceutical Services
Pharmaceutical Services, Online
Pharmacy Services, Online
Pharmacies, Online

Pharmacy services accessed via electronic means.


Sterol Regulatory Element Binding Proteins

Sterol regulatory element binding proteins are basic helix-loop-helix leucine zipper transcription factors that bind the sterol regulatory element TCACNCCAC. They are synthesized as precursors that are threaded into the MEMBRANES of the ENDOPLASMIC RETICULUM.


Nursing, Radiologic and Imaging
Radiologic and Imaging Nursing
Radiologic Nursing

A nursing specialty that deals specifically with the care of patients undergoing diagnostic, neurological, cardiovascular, interventional, ultrasonography, computerized tomography, nuclear medicine, magnetic resonance, radiation oncology or other related procedures .