Jatene Technique
Double-Switch Operation
Senning Procedure
Senning Operation
Arterial Switch Procedure
Mustard Repair
Atrial Switch Operation
Jatene Operation
Mustard Procedure
Rastelli Operation
Arterial Switch Operation
Rastelli Repair
Rastelli Technique
Atrial Switch Repair
Double-Switch Procedure
Double-Switch Technique
Rastelli Procedure
Jatene Procedure
Atrial Switch Procedure
Atrial Switch Technique
Mustard Operation
Arterial Switch Technique

Surgical procedure for anatomical correction of transposed great arteries (e.g., DOUBLE OUTLET RIGHT VENTRICLE).


Purified Protein Derivative of Tuberculin

A protein extracted from boiled culture of tubercle bacilli (MYCOBACTERIUM TUBERCULOSIS). It is used in the tuberculin skin test (TUBERCULIN TEST) for the diagnosis of tuberculosis infection in asymptomatic persons.


Vibrocardiography
Apex Cardiography
Accelography
Cardiography, Apex
Kinetocardiography

The graphic recording of chest wall movement due to cardiac impulses.


Viscum leucarpum
Phoradendron leucarpum
Phoradendron
Mistletoe, American

A plant genus in the family VISCACEAE, order Santalales, subclass Rosidae. Members contain phoratoxin and oleanane TRITERPENES.


Muscular Dystrophy, Congenital, Fukuyama Type

Muscular Dystrophy, Limb-Girdle, Autosomal Recessive, With Mental Retardation

Cerebromuscular Dystrophy, Fukuyama Type

Cerebroocular Dysplasia-Muscular Dystrophy Syndrome

Hydrocephalus, Agyria, And Retinal Dysplasia

Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle), Type C, 1

Muscular Dystrophy-Dystroglycanopathy (Congenital with Brain and Eye Anomalies), Type A, 1

Muscular Dystrophy, Limb-Girdle, Type 2K

Fukuyama Type Congenital Muscular Dystrophy

Congenital Muscular Dystrophy-Dystroglycanopathy with Brain and Eye Anomalies, Type A1

Rare autosomal recessive lissencephaly type 2 associated with congenital MUSCULAR DYSTROPHY and eye anomalies (e.g., RETINAL DETACHMENT; CATARACT; MICROPHTHALMOS). It is often associated with additional brain malformations such as HYDROCEPHALY and cerebellar hypoplasia and is the most severe form of the group of related syndromes (alpha-dystroglycanopathies) with common congenital abnormalities in the brain, eye and muscle development.


Acalypha hispida
Acalypha indica
Acalypha alnifolia
Chenille Plant
Kuppaimeni
Acalypha
Acalypha wilkesiana
Acalypha manniana

Nettle-like plants in the subfamily Acalyphoideae. Acalypha is the largest genus in the Euphorbiaceae family.


Traumatic Spinal Subdural Hematoma
Spinal Subdural Hematoma
Subdural Hematoma, Spinal, Traumatic
Spinal Subdural Hematoma, Traumatic
Hematoma, Subdural, Spinal


Fundulidae
Fundulus
Gulf Killifish
Killifish, Gulf
Topminnows
Mummichog
Fundulus heteroclitus
Killifish
Atlantic Killifish
Fundulus grandis

Common name for Fundulus grandis, an extensively studied fish species used in toxicological and biological investigations.


A naturally-occurring class of MONOTERPENES which occur as a clear colorless liquid at room temperature. Limonene is the major component in the oil of oranges which has many uses, including as flavor and fragrance. It is recognized as safe in food by the Food and Drug Administration (FDA).


Loop Ileostomy
Tube Ileostomy
Ileostomy
Continent Ileostomy
Incontinent Ileostomy

Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.


Central Nervous System Stimulants
Analeptics
Analeptic Agents
Central Stimulants
Analeptic Drugs
CNS Stimulants

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.


Artificial Cells
Artificial Cell
Synthetic Organelles
Artificial Organelles
Synthetic Cells
Protocells

Cell-like structures that contain the minimum of components necessary for carrying out self-sustaining biosynthetic reactions.


Medicaid
Dental Medicaid Programs
Medicaid Program, Dental
Dental Medicaid Program
Medical Assistance, Title 19
Medicaid Programs, Dental

Federal program, created by Public Law 89-97, Title XIX, a 1965 amendment to the Social Security Act, administered by the states, that provides health care benefits to indigent and medically indigent persons.


Paraneoplastic Syndromes, Nervous System

Degenerative or inflammatory conditions affecting the central or peripheral nervous system that develop in association with a systemic neoplasm without direct invasion by tumor. They may be associated with circulating antibodies that react with the affected neural tissue. (Intern Med 1996 Dec;35(12):925-9)


Capillaries
Capillary Beds
Sinusoids
Sinusoidal Beds

The minute vessels that connect arterioles and venules.


Burkholderia cepacia Sepsis
Burkholderia Infections
Infections, Burkholderia
B cepacia Infection
B. cepacia Infection
Burkholderia cepacia Infection

Infections with bacteria of the genus BURKHOLDERIA.


Pharmacopoeias as Topic
National Formulary
Formulary, National

Works about authoritative treatises on drugs and preparations, their description, formulation, analytic composition, physical constants, main chemical properties used in identification, standards for strength, purity, and dosage, chemical tests for determining identity and purity, etc.


Bioinformatics
Computational Molecular Biology
Computational Biology
Molecular Biology, Computational
Bio-Informatics
Biology, Computational

A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.


Angiospasm, Intracranial
Intracranial Vasospasm
Cerebral Angiospasm
Intracranial Vascular Spasm
Cerebrovascular Spasm
Vasospasm, Intracranial
Cerebral Artery Spasm
Cerebral Vasospasm
Intracranial Angiospasm

Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).


Patient Appointments
Patient Schedules
Schedules
Schedules, Patient
Appointments and Schedules
Appointments

The different methods of scheduling patient visits, appointment systems, individual or group appointments, waiting times, waiting lists for hospitals, walk-in clinics, etc.


Balbiani Rings
Chromosomal Puff
Balbiani Ring
Chromosome Puff
Chromosomal Puffs
Chromosome Puffs

Regions along polytene chromosomes that are uncondensed and active in DNA REPLICATION or RNA transcription (GENETIC TRANSCRIPTION).


Endonuclease Hin1076III
Deoxyribonuclease BstFI
Endonuclease LlaCI
Deoxyribonuclease HindIII
Endodeoxyribonuclease BpeI
Endonuclease MkiI
Endonuclease BbrI
Endonuclease Eco65I
Endonuclease ChuI
Endonuclease HinJCII
Endonuclease BpeI
B Pertussis Restriction Enzyme I
Endonuclease BstFI
Deoxyribonuclease EcoVIII
BpeI Endonuclease
Endonuclease Cfr32I
Endonuclease EcoVIII
Endonuclease Eco98I
Endonuclease Hin173I
Endonuclease HindIII
Endonuclease HsuI
Endonuclease HinfII
Endonuclease Asp52I
Endonuclease HinbIII
DNA Restriction Enzyme HindIII

An isoschizomer of HindIII from Lactococcus lactis W15.


Protein Tyrosine Phosphatase, Receptor Type M

Protein Tyrosine Phosphatase, Receptor Type S

Leukocyte Common Antigen-Related Receptor

Receptor Protein Tyrosine Phosphatase mu

Receptor-Like Protein Tyrosine Phosphatases, Class 2A

Protein Tyrosine Phosphatase, Receptor Type D

Protein Tyrosine Phosphatase Like Receptor kappa

Protein Tyrosine Phosphatase, Receptor, Type M

Receptor-Like Protein Tyrosine Phosphatases, Class 2B

Receptor-Like Protein Tyrosine Phosphatase mu

Receptor-Like Protein Tyrosine Phosphatases, Class II

Receptor-Type Protein Tyrosine Phosphatase PTPmu

Receptor Protein Tyrosine Phosphatase psi

Protein Tyrosine Phosphatase, Receptor Type, S

Protein Tyrosine Phosphatase, Receptor Type U

Protein Tyrosine Phosphatase, Receptor Type F

Receptor Protein Tyrosine Phosphatase rho

Protein Tyrosine Phosphatase, Receptor Type K

Receptor-Like Protein Tyrosine Phosphatase kappa

Receptor-Type Tyrosine-Protein Phosphatase F

Leucocyte Common Antigen-Related Receptor

Receptor Protein Tyrosine Phosphatase Sigma

Protein Tyrosine Phosphatase, Receptor Type T

A subclass of receptor-like protein tryosine phosphatases that contain multiple extracellular immunoglobulin G-like domains and fibronectin type III-like domains. An additional memprin-A5-mu domain is found on some members of this subclass.


An enzyme that catalyze the transfer of ADP-RIBOSE from NAD+ to an amino acid residue in a specific protein substrate. This reaction is catalyzed by both mono(ADP-ribose) transferases as well as POLY(ADP-RIBOSE) POLYMERASES. When the term NAD+ ADP-Ribosyltransferase refers to EC 2.4.2.30 it is referring to POLY(ADP-RIBOSE) POLYMERASES.


A genus of livebearing cyprinodont fish comprising the guppy and molly. Some species are virtually all female and depend on sperm from other species to stimulate egg development. Poecilia is used in carcinogenicity studies as well as neurologic and physiologic research.


Rhinorrhea, Cerebrospinal Fluid, Traumatic

Rhinorrhea, Spontaneous Cerebrospinal Fluid

Rhinorrhea, Cerebrospinal Fluid, Spontaneous

Spontaneous Cerebrospinal Fluid Rhinorrhea

Post-Traumatic Rhinorrhea, Cerebrospinal Fluid

Rhinorrhea, Post-Traumatic, Cerebrospinal Fluid

Cerebrospinal Fluid Rhinorrhea, Traumatic

Rhinorrhea, Traumatic Cerebrospinal Fluid

Rhinorrhea, Cerebrospinal Fluid, Post-Traumatic

Cerebrospinal Fluid Rhinorrhea, Post-Traumatic

Post-Traumatic Cerebrospinal Fluid Rhinorrhea

Spontaneous Rhinorrhea, Cerebrospinal Fluid

Cerebrospinal Fluid Rhinorrhea, Spontaneous

Discharge of cerebrospinal fluid through the nose. Common etiologies include trauma, neoplasms, and prior surgery, although the condition may occur spontaneously. (Otolaryngol Head Neck Surg 1997 Apr;116(4):442-9)


A sphingosine-derivative and IMMUNOSUPPRESSIVE AGENT that blocks the migration and homing of LYMPHOCYTES to the CENTRAL NERVOUS SYSTEM through its action on SPHINGOSINE 1-PHOSPHATE RECEPTORS. It is used in the treatment of MULTIPLE SCLEROSIS.


HMN (Hereditary Motor Neuropathy) Proximal Type I

Muscular Atrophy, Spinal, Intermediate Type

Spinal Muscular Atrophy, Mild Childhood and Adolescent Form

Muscular Atrophy, Spinal, Infantile Chronic Form

Proximal Hereditary Motor Neuropathy Type I

A group of recessive inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)


Col Factors
Bacteriocin Plasmids
Bacteriocin Factors
Colicin Factors
Colicin Plasmids


Sulfhydryl Compound Inhibitors
Thiol Reagents
Sulfhydryl Compounds Antagonists
SH-Reagents
Sulfhydryl Reagents
Sulfhydryl Compounds Inhibitors
Sulfhydryl Compound Antagonists

Chemical agents that react with SH groups. This is a chemically diverse group that is used for a variety of purposes. Among these are enzyme inhibition, enzyme reactivation or protection, and labelling.


A benzisoxazole derivative and active metabolite of RISPERIDONE that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST and SEROTONIN 5-HT2 RECEPTOR ANTAGONIST. It is an ANTIPSYCHOTIC AGENT used in the treatment of SCHIZOPHRENIA.


Ventricular Free Wall Rupture
Heart Rupture
Cardiac Rupture
Cardiac Free Wall Rupture
Free Wall Rupture, Heart

Disease-related laceration or tearing of tissues of the heart, including the free-wall MYOCARDIUM; HEART SEPTUM; PAPILLARY MUSCLES; CHORDAE TENDINEAE; and any of the HEART VALVES. Pathological rupture usually results from myocardial infarction (HEART RUPTURE, POST-INFARCTION).


Sperm Immobilizing Agents
Sperm-Immobilizing Effects
Sperm-Immobilizing Effect
Sperm-Immobilizing Agents

Chemical substances with sperm immobilizing activity used as topically administered vaginal contraceptives.


Encephalomalacia
Multicystic Encephalomalacia
Cerebromalacia
Encephalomalacia, Multicystic

Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia (see BRAIN ISCHEMIA), infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75)


Mammary Epithelium, Human
Mammary Epithelia, Human
Mammary Ducts, Human
Mammary Glands, Human
Human Mammary Glands
Mammary Alveoli, Human
Mammary Lobules, Human
Mammary Gland
Mammary Glands
Human Mammary Gland

Glandular tissue in the BREAST of human that is under the influence of hormones such as ESTROGENS; PROGESTINS; and PROLACTIN. In WOMEN, after PARTURITION, the mammary glands secrete milk (MILK, HUMAN) for the nourishment of the young.


Henipavirus Infections
NiV Infection
Hendra Virus Infections
Nipah Virus Encephalitis
Nipah Virus Infection

Infections with viruses of the genus HENIPAVIRUS, family PARAMYXOVIRIDAE.


alpha-Ketoglutaric Acid, Calcium Salt (2:1)

alpha-Ketoglutaric Acid, Diammonium Salt

alpha-Ketoglutaric Acid, Monosodium Salt

alpha-Ketoglutaric Acid, Dipotassium Salt

alpha-Ketoglutaric Acid, Monopotassium Salt

A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)


Killer Cell Lectin-Like Receptor Subfamily B

NK Cell Lectin-Like Receptor Subfamily B, Member 1

A subclass of NK cell lectin-like receptors that includes both inhibitory and stimulatory members.


A ribonucleoside in which RIBOSE is linked to URACIL.


Bigumal
Chloroguanide
Chloroguanide Hydrochloride
Paludrine
Proguanil
Proguanil Hydrochloride
Chloriguane
Chlorguanid
Paludrin

A biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.


Surgical Procedure, Endoscopic, Digestive System

Procedure, Digestive System, Endoscopic, Surgical

Digestive System Endoscopic Surgical Procedures

Surgical Procedures, Endoscopic, Digestive System

Procedure, Endoscopic, Digestive System, Surgical

Endoscopic, Digestive System, Surgical Procedure

Procedures, Digestive System, Endoscopic, Surgical

Procedures, Endoscopic, Digestive System, Surgical

Endoscopic examination, therapy or surgery of the digestive tract.


Traumatic Cerebral Intraparenchymal Hemorrhage

Cerebral Parenchymal Hemorrhage, Traumatic

Cerebral Intraparenchymal Hemorrhage, Traumatic

Cerebral Intraparenchymal Hematoma, Traumatic

Traumatic Cerebral Intraparenchymal Hematoma

Traumatic Cerebral Parenchymal Hemorrhage

Bleeding into one or both CEREBRAL HEMISPHERES due to TRAUMA. Hemorrhage may involve any part of the CEREBRAL CORTEX and the BASAL GANGLIA. Depending on the severity of bleeding, clinical features may include SEIZURES; APHASIA; VISION DISORDERS; MOVEMENT DISORDERS; PARALYSIS; and COMA.


Sus scrofa
Wild Boar
Pig, Domestic
Sus scrofa domestica

The domestic pig, a subspecies of SUS SCROFA.


Phodopus campbelli
Siberian Hamster
Djungarian
Djungarian Hamsters
Hamsters, Siberian
Phodopus sungorus
Phodopus
Hamsters, Djungarian
Phodopus sungorus campbelli

A genus of hamsters characterized by small size, very short tail, and short, broad feet with hairy soles.


A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.


Physostigma venenosum
Calabar Bean
Physostigma

A plant genus of the family FABACEAE that is a source of PHYSOSTIGMINE.


Mucopolysaccharidosis Type IV B
Morquio Syndrome, Type B
Morquio Disease
Mucopolysaccharidosis Type IV
Mucopolysaccharidosis 4
MPS IVB
Morquio Syndrome A
MPS IVA
Morquio Syndrome
Mucopolysaccharidosis 4B
MPS IV B
Morquio's Disease Type B
Morquio A Disease
Mucopolysaccharidosis IV
Eccentroosteochondrodysplasia
Mucopolysaccharidosis Type IV A
Morquio's Disease
Morquio-B Disease
Galactosamine-6-Sulfatase Deficiency
Morquio's Syndrome
Mucopolysaccharidosis Type IVB
MPS IV A
Mucopolysaccharidosis Type IVA
Eccentro-Osteochondrodysplasia
GALNS Deficiency
Morquio Syndrome B
Morquio B Syndrome

Genetic disorder of mucopolysaccharide metabolism characterized by skeletal abnormalities, joint instability, development of cervical myelopathy, and excessive urinary keratan sulfate. There are two biochemically distinct forms, each due to a deficiency of a different enzyme.


Mycamine
Micafungin Sodium
FK-463
Micafungin
FK463
FK 463

A cyclic lipo-hexapeptide echinocandin antifungal agent that is used for the treatment and prevention of CANDIDIASIS.


Syphilitic Aortitis
Cardiovascular Syphilis
Aortitis, Syphilitic
Syphilis, Cardiovascular

Cardiovascular manifestations of SYPHILIS, an infection of TREPONEMA PALLIDUM. In the late stage of syphilis, sometimes 20-30 years after the initial infection, damages are often seen in the blood vessels including the AORTA and the AORTIC VALVE. Clinical signs include syphilitic aortitis, aortic insufficiency, or aortic ANEURYSM.


Tubal Embryo Stage Transfer
Blastocyst Transfer
Tubal Embryo Transfer
Embryo Transfer

The delayed transfer of embryos at the blastocyst stage provides a means to eliminate unhealthy embryos that do not develop normally. The selection and transfer of superior blastocysts reduces the need for multiple-embryo transfer and the risks of high-order multiple gestation.


3-Phenylchromones. Isomeric form of FLAVONOIDS in which the benzene group is attached to the 3 position of the benzopyran ring instead of the 2 position.


Fensel
Felocor
Plendil
Flodil
H 154-82
Felo Biochemie
Modip
Perfudal
Felodipin Heumann
Felogamma
Felodipin AZU
Felodipin Von Ct
Agon
Felodipine
Felo-Puren
Felodipin Dura
Felodipin-Ratiopharm
Felobeta
Munobal
Felodipin Stada
Felodipin AL
Felodipin AbZ
Felodur
Felodipin 1A Pharma
Renedil

A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels.


Schizophreniform Catatonia
Catatonia, Organic
Lethal Catatonia
Catatonia, Malignant
Organic Catatonic Disorder
Catatonia

A neuropsychiatric disorder characterized by one or more of the following essential features: immobility, mutism, negativism (active or passive refusal to follow commands), mannerisms, stereotypies, posturing, grimacing, excitement, echolalia, echopraxia, muscular rigidity, and stupor; sometimes punctuated by sudden violent outbursts, panic, or hallucinations. This condition may be associated with psychiatric illnesses (e.g., SCHIZOPHRENIA; MOOD DISORDERS) or organic disorders (NEUROLEPTIC MALIGNANT SYNDROME; ENCEPHALITIS, etc.). (From DSM-IV, 4th ed, 1994; APA, Thesaurus of Psychological Index Terms, 1994)


Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC45 Isoform

Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC48 Isoform

A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.


Compression Stockings
Stockings, Compression
Stockings, Elastic
Elastic Stockings

Tight coverings for the foot and leg that are worn to aid circulation in the legs, and prevent the formation of EDEMA and DEEP VEIN THROMBOSIS. PNEUMATIC COMPRESSION STOCKINGS serve a similar purpose especially for bedridden patients, and following surgery.


Rapeseed Oil
Low Erucic Acid Rapeseed Oil
LEAR Oil
Canadian Oil
Canola Oil

RAPESEED OIL derivative; the word Canola stands for Canadian Oil Low Acid.


A genus in the family of EARLESS SEALS (Phocidae) and collectively the most abundant PINNIPEDS in the Northern Hemisphere.


Quso G32
Silicon Dioxide
Aerosil
Quso G-32
Silica
Tridymite
Aerosil 380
Cristobalite

Transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid.


A naphthalene derivative that inhibits fungal SQUALENE EPOXIDASE and is used to treat DERMATOMYCOSES of the skin and nails.


Monocyte Chemoattractant Protein 1 Receptor

CCR receptors with specificity for CHEMOKINE CCL2 and several other CCL2-related chemokines. They are expressed at high levels in T-LYMPHOCYTES; B-LYMPHOCYTES; MACROPHAGES; BASOPHILS; and NK CELLS.


Ixodes dammini
Ixodes
Ixodes scapularis
Black-legged Tick
Castor Bean Tick
Deer Tick
Ixodes ricinus
Ixodes persulcatus

The largest genus of TICKS in the family IXODIDAE, containing over 200 species. Many infest humans and other mammals and several are vectors of diseases such as LYME DISEASE, tick-borne encephalitis (ENCEPHALITIS, TICK-BORNE), and KYASANUR FOREST DISEASE.


A pyridine and sulfonamide derivative that acts as a sodium-potassium chloride symporter inhibitor (loop diuretic). It is used for the treatment of EDEMA associated with CONGESTIVE HEART FAILURE; CHRONIC RENAL INSUFFICIENCY; and LIVER DISEASES. It is also used for the management of HYPERTENSION.


Behavioral Assessment of Dysexecutive Syndrome

Repeatable Battery for the Assessment of Neuropsychological Status

Cambridge Neuropsychological Test Automated Battery

Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.


A nitrovinyl furan used as a schistosomicidal agent and proposed for trypanosomiasis, especially Chagas disease.


Dressings, Biological
Biological Dressings
Porcine Xenograft Dressings
Dressing, Biological
Biologic Dressing
Amniotic Membrane Dressings
Pig Skin Dressings
Allograft Dressings
Heterograft Dressings
Xenograft Dressings
Homograft Dressings

Human or animal tissue used as temporary wound coverings.


Zeugmatography
Chemical Shift Imaging
Magnetic Resonance Imaging
Steady-State Free Precession MRI
Spin Echo Imaging
Magnetization Transfer Contrast Imaging
Magnetic Resonance Imaging, Functional
NMR Imaging
Tomography, MR
MRI Scans
fMRI
Imaging, Chemical Shift
MR Tomography
NMR Tomography
Proton Spin Tomography
Tomography, NMR
Tomography, Proton Spin
MRI, Functional
Functional Magnetic Resonance Imaging

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.


Myrrh, Bisabol
Commiphora kataf
Commiphora
Bisabol Myrrh
Common Myrrh Tree
Commiphora mukul
Guggul Tree
Commiphora erythraea
Commiphora myrrha
Commiphora wightii
Commiphora molmol

A plant genus of the family BURSERACEAE which is a source of gugulipid and guggulu extract. Balm of Gilead is a common name more often referring to POPULUS and sometimes to ABIES.


Orally active semisynthetic cephalosporin antibiotic with broad-spectrum activity.


Aldomet Dopegit alpha-Methyl-L-Dopa Sembrina Dopegyt Alphamethyldopa Methyldopa Dopergit Hydopa alpha-Methyldopa Methyldopate Apo-Methyldopa Dopamet Nu-Medopa Meldopa

An alpha-2 adrenergic agonist that has both central and peripheral nervous system effects. Its primary clinical use is as an antihypertensive agent.


Clathrin Assembly Protein Complex sigma Subunits

A family of small adaptin protein complex subunits of approximately 19 KDa in size.


Isotopically-Coded Affinity Tagging
Isotope-Coded Affinity Tagging
Isotope Labeling, Stable
Isotope Labeling


Injuries, Craniocerebral
Head Trauma
Occipital Trauma
Forehead Trauma
Head Injuries
Superficial Head Injury
Head Injury, Open
Frontal Region Trauma
Injuries, Head
Parietal Region Trauma
Head Injury, Minor
Occipital Region Trauma
Temporal Region Trauma
Multiple Head Injuries
Craniocerebral Trauma
Trauma, Head
Crushing Skull Injury
Open Head Injury
Head Injuries, Multiple
Craniocerebral Injuries
Head Injury, Superficial

Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.


Ha-ras Genes
K-ras Genes
v-Ha-ras Genes
c-H-ras Genes
Ki-ras Oncogenes
v-Ki-ras Genes
c-Ha-ras Genes
Ha-ras Oncogenes
v-K-ras Oncogenes
v-H-ras Oncogenes
v-Ha-ras Oncogenes
N-ras Oncogenes
ras Oncogene
c-Ki-ras Genes
c-H-ras Proto-Oncogenes
c-N-ras Proto-Oncogenes
c-K-ras Genes
c-Ha-ras Proto-Oncogenes
c-N-ras Genes
Ki-ras Genes
v-Ki-ras Oncogenes
K-ras Oncogenes
v-K-ras Genes
Genes, ras
c-Ki-ras Proto-Oncogenes
c-K-ras Proto-Oncogenes
N-ras Genes
ras Genes
v-H-ras Genes
H-ras Genes
H-ras Oncogenes

Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.


Epulides, Giant Cell
Peripheral Giant Cell Granuloma
Granuloma, Giant Cell Reparative
Giant Cell Granuloma
Epulis, Giant Cell
Granuloma, Giant Cell

A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.


ATPases that are members of the AAA protein superfamily (ATPase family Associated with Diverse cellular Activities). The NSFs functions, acting in conjunction with SOLUBLE NSF ATTACHMENT PROTEINS (i.e. SNAPs, which have no relation to SNAP 25), are to dissociate SNARE complexes.


Sun Glasses, Nonprescription
Safety Lenses
Goggles
Safety Glasses
Eye Protective Devices

Personal devices for protection of the eyes from impact, flying objects, glare, liquids, or injurious radiation.


Appetite-Regulating Hormone
Ghrelin
Gastric MLTRP
PpMTLRP
Ppghrelin
Obestatin
Ghrelin-Obestatin Preprohormone
Motilin-Related Peptide Precursor
Ghrelin Precursor
GHRL Protein
Motilin-Related Peptide

A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.


Vertebral Column
Vertebra
Vertebrae
Spinal Column
Spine


An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.


Ribonucleoproteins, U6 Small Nuclear
Ribonucleoproteins, U4 Small Nuclear
Small Nuclear Ribonucleoproteins, U6
U6 snRNP
U4-U6 Small Nuclear Ribonucleoproteins
Ribonucleoproteins, Small, U4-U6
Small Nuclear Ribonucleoproteins, U4
U4 Small Nuclear Ribonucleoproteins
U6 Small Nuclear Ribonucleoproteins
U4-U6 snRNP
Small Nuclear Ribonucleoproteins, U4-U6
Ribonucleoprotein, U4-U6 Small Nuclear
U4 snRNP

A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U4-U6 snRNP along with the U5 snRNP preassemble into a single 25S particle that binds to the U1 and U2 snRNPs and the substrate to form mature SPLICEOSOMES. There is also evidence for the existence of individual U4 or U6 snRNPs in addition to their organization as a U4-U6 snRNP.


Ig-like Domain
Immunoglobulin C1-set Domain
Ig V-set Domain
Ig Domain
Immunoglobulin Domains
Ig Fold
Ig C2-set Domain
Immunoglobulin C2-set Domain
Ig Domains
Immunoglobulin-like Domain
Immunoglobulin Domain
Immunoglobulin V-set Domain
Immunoglobulin I-set Domain

Immunoglobulin-like domains similar to those of the immunoglobulin variable region. They occur in diverse protein families, including IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; T-CELL RECEPTORS;JUNCTIONAL ADHESION MOLECULES; and RECEPTOR PROTEIN-TYROSINE KINASES.


Survival of Motor Neuron Complex Proteins

Survival of Motor Neuron Protein-Interacting Protein 1

A complex of proteins that assemble the SNRNP CORE PROTEINS into a core structure that surrounds a highly conserved RNA sequence found in SMALL NUCLEAR RNA. They are found localized in the GEMINI OF COILED BODIES and in the CYTOPLASM. The SMN complex is named after the Survival of Motor Neuron Complex Protein 1, which is a critical component of the complex.


Mumps Vaccine, Inactivated
Mumps Vaccine
Inactivated Mumps Virus Vaccine
Inactivated Mumps Vaccine
Live Attenuated Mumps Vaccine
Live Attenuated Mumps Virus Vaccine
Mumps Virus Vaccine, Live Attenuated
Mumps Vaccine, Live Attenuated
Mumps Virus Vaccine, Inactivated

Vaccines used to prevent infection by MUMPS VIRUS. Best known is the live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.


Recombinase Resolvase Recombinases Resolvases

A broad category of enzymes that are involved in the process of GENETIC RECOMBINATION.


Greater Sac
Omental Bursa
Peritoneal Cavity
Lesser Sac

The space enclosed by the peritoneum. It is divided into two portions, the greater sac and the lesser sac or omental bursa, which lies behind the STOMACH. The two sacs are connected by the foramen of Winslow, or epiploic foramen.


Keratosis Palmoplantaris Transgradiens of Siemens

Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis).


Gentiana lutea
Yellow Gentian
Gentiana
Gentian

A plant genus of the family Gentianaceae whose members contain SECOIRIDOIDS and have been used in TRADITIONAL MEDICINE for suppressing INFLAMMATION.


Crouzon Craniofacial Dysostosis
Craniofacial Dysostosis
Crouzon Disease
Crouzon Syndrome
Dysostosis, Craniofacial
Craniofacial Dysarthrosis
Crouzon's Disease
Craniofacial Dysostosis Type 1
Craniofacial Dysostosis Syndrome
Craniofacial Dysostosis, Type I

Autosomal dominant CRANIOSYNOSTOSIS with shallow ORBITS; EXOPHTHALMOS; and maxillary hypoplasia.


Demethyl Epipodophyllotoxin Ethylidine Glucoside

A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.


Prometazin
Isopromethazine
Phensedyl
Rumergan
Promet
Pipolphen
Diphergan
Promethazine Hydrochloride
Pyrethia
Atosil
Diprazin
Pipolfen
Promethazine
Phenargan
Remsed
Phenergan
Proazamine
Prothazin

A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.


Anterior Optic Neuritis
Posterior Optic Neuritis
Optic Neuritis
Retrobulbar Neuritis
Neuropapillitis

Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).


Indoor Air Pollution
Air Quality, Indoor
Air Pollution, Indoor
Indoor Air Quality


The state of conforming to a type, standard, or regular pattern. (Merriam-Webster's Collegiate Dictionary, 10th ed)


Biochemical Processes
Biochemical Phenomenon
Biochemical Concepts
Phenomena, Biochemical
Biochemical Phenomena
Biochemical Process

The chemical processes, enzymatic activities, and pathways of living things and related temporal, dimensional, qualitative, and quantitative concepts.


Neurogenic Dysfunction of the Urinary Bladder

Dysfunction of the URINARY BLADDER due to disease of the central or peripheral nervous system pathways involved in the control of URINATION. This is often associated with SPINAL CORD DISEASES, but may also be caused by BRAIN DISEASES or PERIPHERAL NERVE DISEASES.


Antley-Bixler Syndrome-Like Phenotype With Disordered Steroidogenesis

Antley-Bixler Syndrome, Autosomal Dominant

Congenital Adrenal Hyperplasia Due To Apparent Combined P450c17 and P450c21 Deficiency

Osteodysgenesis, Multisynostotic, With Fractures

Combined Partial Deficiency of 17-Hydroxylase and 21-Hydroxylase

Adrenal Hyperplasia, Congenital, Due To Cytochrome P450 Oxidoreductase Deficiency

Disordered Steroidogenesis Due To Cytochrome P450 Oxidoreductase Deficiency

Multisynostotic Osteodysgenesis With Long Bone Fractures

Antley-Bixler Syndrome with Disordered Steroidogenesis

Antley-Bixler Syndrome phenotype with normal genitalia and normal steroidogenesis, and associated with autosomal dominant mutations in FGFR2, the gene for FIBROBLAST GROWTH FACTOR RECEPTOR 2.


Facial Myokymia
Facial Nerve Sensory Disorders
Motor Disorders, Facial Nerve
Facial Neuritis
Seventh Cranial Nerve Diseases
Facial Nerve Diseases
Geniculate Ganglionitis
Cranial Nerve VII Disorders
Acquired Facial Neuropathy
Facial Nerve Motor Disorders
Facial Nerve Disorders
Familial Facial Neuropathy
Facial Neuropathy
Sensory Disorders, Facial Nerve
Cranial Nerve VII Diseases

Diseases of the facial nerve or nuclei. Pontine disorders may affect the facial nuclei or nerve fascicle. The nerve may be involved intracranially, along its course through the petrous portion of the temporal bone, or along its extracranial course. Clinical manifestations include facial muscle weakness, loss of taste from the anterior tongue, hyperacusis, and decreased lacrimation.


Surgery, Cardiac
Surgery, Thoracic
Thoracic Surgery
Surgery, Heart
Heart Surgery
Cardiac Surgery

A surgical specialty concerned with diagnosis and treatment of disorders of the heart, lungs, and esophagus. Two major types of thoracic surgery are classified as pulmonary and cardiovascular.


Type 3 Inositol 1,4,5-trisphosphate Receptor

Type 1 Inositol 1,4,5-trisphosphate Receptor

Inositol 1,4,5-trisphosphate Receptor Subtype 3

Inositol 1,4,5-trisphosphate Receptor Type 3

Inositol 1,4,5-trisphosphate Receptor Type 2

Inositol 1,4,5-trisphosphate Receptor Type 1

Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.


Germacranes
Sesquiterpenes, Germacrane
Germacrane Derivatives

SESQUITERPENES cyclized to one 10-carbon ring.


Peripheral Autoimmune Demyelinating Disease

Demyelinating Autoimmune Disease, Peripheral

Demyelinating Disease, Peripheral Autoimmune

Autoimmune Demyelinating Disease, Peripheral

Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.


Auriculo-Ventricular Dissociation
Atrioventricular Dissociation
A-V Dissociation
Heart Block

Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.


Aid to Totally Disabled Persons
Aid to Visually Impaired
Aid to Visually Impaired Persons
Aid to the Blind
Social Insurance
Aid to the Totally Disabled
Social Security

Government sponsored social insurance programs.


Intracranial Embolism and Thrombosis
Cerebral Embolism and Thrombosis
Brain Embolism and Thrombosis
Embolism and Thrombosis, Brain

Embolism or thrombosis occurring in a cerebral vessel often leading to cerebral infarction.


Pseudomembranous Enterocolitis
Colitis, Pseudomembranous
Pseudomembranous Colitis
Enteritis, Pseudomembranous
Antibiotic-Associated Colitis
Clostridium Enterocolitis
Pseudomembranous Enteritis
Enterocolitis, Pseudomembranous

An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.


Umbellularia
Bay Laurel, California
California Bay Laurel

The common English name used for the aromatic leaves of Umbellularia.


Antigale
Carbaryl
Tigal
Carbyl
Océcoxil
Poudre insecticide Moureau
Poudre insecticide Vetoquinol
Joseph Lyddy
Dog-Net Insecticide Poudre
1-Naphthyl-N-methylcarbamate
Carylderm
G-Wizz
Fido's Free-Itch
Carbaryl, Nickel (2+) Salt
Carbaril
Sépou
Concentrat VO 18
Carbaryl, Manganese (2+) Salt
Poutic
Skatta Tick Flea Louse Powder
Sevin

A carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly low toxicity from dermal absorption and is used for control of head lice in some countries.


Bioflutin
etil von ct
Etilefrin AL
Ethylphenylephrine
Adrenam
Etilefrin
Fetanol
Etilefrine Hydrochloride
Ethyladrianol
Circupon
Eti-Puren
Phetanol
Effortil
Etilefrine
Etilefrine Pivalate Hydrochloride
Ethyl Adrianol
Ethylnorphenylephrine
Thomasin
Efortil
Etilefrin-ratiopharm
Cardanat

A phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.


Maze Procedure
Maze IV Procedure
Cox-Maze Procedure
Mini Maze Procedure
Cox Maze IV Procedure
Cox Maze III Procedure
Maze III Procedure
Maze Ablation
Left-sided Maze Procedure
Cox-Maze Operation
Maze Surgery
Cox Maze III Surgery

A surgical treatment in which heart tissue is scarred (cut-and-sew method), excised or otherwise destroyed in an open chest approach to direct electrical signals through a more controlled path via the ATRIOVENTRICULAR NODE. It is often used to restore normal rhythms in ATRIAL FIBRILLATION.


Health Plans, Accountable
Competition, Managed
Managed Competition
Accountable Health Plans

A strategy for purchasing health care in a manner which will obtain maximum value for the price for the purchasers of the health care and the recipients. The concept was developed primarily by Alain Enthoven of Stanford University and promulgated by the Jackson Hole Group. The strategy depends on sponsors for groups of the population to be insured. The sponsor, in some cases a health alliance, acts as an intermediary between the group and competing provider groups (accountable health plans). The competition is price-based among annual premiums for a defined, standardized benefit package. (From Slee and Slee, Health Care Reform Terms, 1993)


Radiotherapy, High-Energy
Radiotherapy, Megavolt
High-Energy Radiotherapy
Megavolt Radiotherapy

Radiotherapy using high-energy (megavolt or higher) ionizing radiation. Types of radiation include gamma rays, produced by a radioisotope within a teletherapy unit; x-rays, electrons, protons, alpha particles (helium ions) and heavy charged ions, produced by particle acceleration; and neutrons and pi-mesons (pions), produced as secondary particles following bombardment of a target with a primary particle.


Human Enterovirus A
Human Enterovirus 71
Enterovirus 71, Human
Enterovirus A, Human

A type A enterovirus prominently associated with hand, foot, and mouth disease, acute pulmonary edema, and serious neurologic syndromes.


Amfetamine
Phenamine
Mydrial
Amphetamine Sulfate
Thyramine
Amphetamine Sulfate (2:1)
levo-Amphetamine
l-Amphetamine
Levoamphetamine
Centramina
Fenamine
Desoxynorephedrin
Phenopromin
Amphetamine

A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.


Aroclor 1254
Aroclor-1254
Chlorodiphenyl (54% Chlorine)

A mixture of polychlorinated biphenyls that induces hepatic microsomal UDP-glucuronyl transferase activity towards thyroxine.


Bilirubin, (15E)-Isomer
Hematoidin
Bilirubin IX alpha
Bilirubin
Bilirubin, Calcium Salt
Bilirubin, Disodium Salt
delta-Bilirubin
Bilirubin, (4E,15E)-Isomer
Calcium Bilirubinate
Bilirubin, (4E)-Isomer
Bilirubin, Monosodium Salt

A bile pigment that is a degradation product of HEME.


A quinoline and tetrazole derivative that acts as a phosphodiesterase type 3 inhibitor, with anti-platelet and vasodilating activity. It is used in the treatment of PERIPHERAL VASCULAR DISEASES; ISCHEMIC HEART DISEASE; and in the prevention of stroke.


cdc42 GTP-Binding Protein, Saccharomyces cerevisiae

A member of the Rho family of MONOMERIC GTP-BINDING PROTEINS from SACCHAROMYCES CEREVISIAE. It is involved in morphological events related to the cell cycle. This enzyme was formerly listed as EC 3.6.1.47.


Superconducting Coil
Superconductors
Superconducting Magnets
Superconductivity
Meissner Effect


An ansa macrolide isolated from the MAYTENUS genus of East African shrubs.


Hepatobiliary Elimination
Hepatic Elimination
Hepatic Excretion
Biliary Excretion
Hepatobiliary Excretion
Biliary Elimination

The removal of substances from the blood supply via the LIVER and BILIARY TRACT.


Mycobiome
Fungal Microbiota
Fungal Microbiome
Fungal Community

The full spectrum of FUNGI that exist within a particular biological niche such as an organism, soil, a body of water, etc.


Xanthium
Cocklebur, Spiny
Cocklebur
Xanthium spinosum

Xanthium spinosum L. is considered a noxious weed.


Rock and Roll Music
Vocal Melody
Classical Music
Music
Hip Hop Music
Songs
Rap Music
Jazz Music

A serious and conventional form of music involving orchestral movements that was developed during the eighteenth and nineteenth centuries.


Molecular Diagnostics
Diagnostic Molecular Pathology
Pathology, Molecular

A subspecialty of pathology concerned with the molecular basis (e.g., mutations) of various diseases.


Spinner Dolphins
Stenella frontalis
Stenella coeruleoalba
Stenella longirostris
Stenella
Spotted Dolphins
Striped Dolphin

A genus comprised of spinner, spotted, and striped DOLPHINS, in the family Delphinidae. Schools of Stenella, that may number in the thousands, often associate with schools of TUNA, and are thus vulnerable to accidental harvesting.


Endometrial Stromal Tumors
Endolymphatic Stromal Myosis
Sarcoma, Endometrial Stromal, Low-Grade

Neoplasms of the endometrial stroma that sometimes involve the MYOMETRIUM. These tumors contain cells that may closely or remotely resemble the normal stromal cells. Endometrial stromal neoplasms are divided into three categories: (1) benign stromal nodules; (2) low-grade stromal sarcoma, or endolymphatic stromal myosis; and (3) malignant endometrial stromal sarcoma (SARCOMA, ENDOMETRIAL STROMAL).


Dragline Silk Fibroins
Fibroin
Silk Fibroin
Silk Fibroins
Fibroins
Fibroins, Spider
Spidroins

Fibrous proteins secreted by INSECTS and SPIDERS. Generally, the term refers to silkworm fibroin secreted by the silk gland cells of SILKWORMS, Bombyx mori. Spider fibroins are called spidroins or dragline silk fibroins.


Mesothelium
Epithelial Tissue
Mesothelial Tissue
Epithelium

The layers of EPITHELIAL CELLS which cover the inner and outer surfaces of the cutaneous, mucus, and serous tissues and glands of the body.


Plant-Based Nutrition
Lacto-Vegetarian Diet
Plant-Based Diet
Lacto-Ovo Vegetarian Diet
Diet, Plant-Based
Vegetarianism
Vegetarian Diet
Diet, Vegetarian

The dietary practice of completely avoiding meat or fish products in the DIET, consuming VEGETABLES, CEREALS, and NUTS. Some vegetarian diets called lacto-ovo also include milk and egg products.


Box Elder
Elder, Box
Acer
Acer negundo
Maple
Acer saccharum
Sugar Maple

A plant genus of the family SAPINDACEAE, best known for trees with palmately lobed leaves.


Genetic Pleiotropism
Pleiotropic Gene
Pleiotropic Genes
Genetic Pleiotropy

A single gene that influences several distinct and seemly unrelated phenotypic outcomes.


Primarily a technique of group psychotherapy which involves a structured, directed, and dramatized acting out of the patient's personal and emotional problems.


Organizations
Nongovernmental Organizations
Organizations, Nongovernmental
Non-Governmental Organizations

Groups of people working together in a structured manner to pursue common goals and objectives.


Medical History, 17th Cent.
17th Century History
History, 17th Century
Historical Events, 17th Century
17th Cent. History of Medicine
History of Medicine, 17th Cent.
Medicine, 17th Cent.
17th Cent. History (Medicine)
History, Seventeenth Century
17th Cent. Medicine

Events of lasting impact or importance occurring in the 17th century.


Transducin, gamma Subunit
Transducin, alpha Subunit
alpha-Transducin
gamma-Transducin
beta-Transducin
Transducin, beta Subunit
Transducin
G-Protein, Inhibitory Gt
Gt, Transducin G-Protein
Transducin G-Protein (Gt)

A heterotrimeric GTP-binding protein that mediates the light activation signal from photolyzed rhodopsin to cyclic GMP phosphodiesterase and is pivotal in the visual excitation process. Activation of rhodopsin on the outer membrane of rod and cone cells causes GTP to bind to transducin followed by dissociation of the alpha subunit-GTP complex from the beta/gamma subunits of transducin. The alpha subunit-GTP complex activates the cyclic GMP phosphodiesterase which catalyzes the hydrolysis of cyclic GMP to 5'-GMP. This leads to closure of the sodium and calcium channels and therefore hyperpolarization of the rod cells.


Sustained Low-Efficiency Daily Diafiltration

Procedures involving non-continuous blood purification (e.g., dialysis, filtration or perfusion) via vascular access with settings for dialysate and blood flow rates and treatment duration settings hybrid between CRRT TECHNIQUE and IRRT TECHNIQUE.


Death-Associated Protein Kinase-Related Protein 1

A family of calcium/calmodulin-dependent PROETIN-SERINE-THREONINE KINASES. They are ubiquitously expressed in adult and embryonic mammalian tissues, and their functions are tightly related to the early stages of eukaryotic programmed cell death.


Muscarinic Effects
Cholinergic Effects
Acetylcholine Agents
Muscarinic Effect
Nicotinic Effects
Cholinomimetics
Muscarinic Agents
Cholinergic Agents
Nicotinic Agents
Cholinergics
Nicotinic Effect
Cholinergic Effect
Cholinergic Drugs
Muscarinics

Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage.


Protein Phosphatase 2A, Catalytic Subunit, alpha Isoform

Protein Phosphatase 2A, Regulatory Subunit B, beta Isoform

Protein Phosphatase 2A, Regulatory Subunit B, gamma Isoform

Protein Phosphatase 2, Regulatory Subunit B, beta Isoform

Protein Phosphatase 2, Regulatory Subunit B, delta Isoform

Protein Phosphatase 2, Catalytic Subunit, beta Isoform

Protein Phosphatase 2, Catalytic Subunit, alpha Isoform

Protein Phosphatase 2A, Regulatory Subunit A , alpha Isoform

Protein Phosphatase 2A, Regulatory Subunit A, beta Isoform

Protein Phosphatase 2, Regulatory Subunit B, gamma Isoform

Protein Phosphatase 2, Regulatory Subunit B, alpha Isoform

Protein Phosphatase 2A, Catalytic Subunit, beta Isoform

Protein Phosphatase 2, Regulatory Subunit A, beta Isoform

Protein Phosphatase 2, Regulatory Subunit A, alpha Isoform

Protein Phosphatase 2A, Regulatory Subunit B, alpha Isoform

Protein Phosphatase 2A, Regulatory Subunit B, delta Isoform

Serine-Threonine-Protein Phosphatase 2A Catalytic Subunit alpha Isoform

Serine Threonine Protein Phosphatase 2A Catalytic Subunit beta Isoform

A phosphoprotein phosphatase subtype that is comprised of a catalytic subunit and two different regulatory subunits. At least two genes encode isoforms of the protein phosphatase catalytic subunit, while several isoforms of regulatory subunits exist due to the presence of multiple genes and the alternative splicing of their mRNAs. Protein phosphatase 2 acts on a broad variety of cellular proteins and may play a role as a regulator of intracellular signaling processes.


Androgen-Dependent Epididymal Secretory Proteins

Epididymal secretory proteins that are stimulated by androgen.


An indole sulfonamide compound and inhibitor of BRAF KINASES that is used for the treatment of unresectable or metastatic MELANOMA.


Cytochrome P-450 CYP3A4 Inducers
P450 CYP3A4 Inducers
P450 CYP3A7 Inducers
Cytochrome P-450 CYP3A7 Inducers
CYP3A7 Inducers
P450 CYP3A Inducers
P450 CYP3A5 Inducers
CYP3A Inducers
Cytochrome P-450 CYP3A Inducers
Cytochrome P-450 CYP3A5 Inducers
CYP3A5 Inducers
CYP3A4 Inducers

Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP3A.


Afibrinogenemia, Congenital
Fibrinogen Deficiency
Congenital Afibrinogenaemia
Afibrinogenemia
Deficiency, Fibrinogen
Hypofibrinogenemia, Congenital
Familial Afibrinogenemia
Congenital Afibrinogenemia

A deficiency or absence of FIBRINOGEN in the blood.


Fusidate Sodium
Stanicide
Fusidic Acid
Fusidin
Sodium Fusidate
Silver Fusidate
Fusidic Acid, Sodium Salt
Fucithalmic

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.


Hydroxyethyl Starch (130 KD-0.4 Substitution)

Hydroxyethyl starch derivative with five hydroxyethyl groups.


Radiography of any part of the URINARY TRACT.


Radiation, Beta
Beta Radiation
Beta Particles
Beta Rays

A stream of high energy POSITRONS or ELECTRONS ejected from a disintegrating atomic nucleus.


Liriodendron
Yellow Poplar
Liriodendron tulipifera
Tulip Tree
Poplar, Yellow

A plant genus of the family MAGNOLIACEAE. Members include hardwood trees of eastern North America with distinct large tuliplike flowers.


Escherichia coli O104
E coli O104-H4
Escherichia coli O104-H4
E coli O104

An enterohemorrhagic Escherichia coli of the O subfamily that can cause severe FOODBORNE DISEASE. The H4 serotype strain produces SHIGA TOXINS and has been linked to human disease outbreaks, including some cases of HEMOLYTIC-UREMIC SYNDROME, resulting from contamination of foods by feces containing E. coli O104.


Induced Abortion
Abortion (Induced)
Previous Abortion
Abortion Techniques
Anti-Abortion Groups
Embryotomy
Abortion, Drug-Induced
Abortion, Saline-Solution
Fertility Control, Postconception
Abortion Failure
Abortion, Rivanol
Abortion, Soap-Solution
Abortion Rate
Abortion Technics
Abortion History
Abortion, Induced

Intentional removal of a fetus from the uterus by any of a number of techniques. (POPLINE, 1978)


Tricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.


Health-Related Quality Of Life
Quality of Life
Life Quality
HRQOL

A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral, social environment as well as health and disease.


Isolated Somatotropin Deficiency Disorder

Isolated Human Growth Hormone Deficiency

A form of dwarfism caused by complete or partial GROWTH HORMONE deficiency, resulting from either the lack of GROWTH HORMONE-RELEASING FACTOR from the HYPOTHALAMUS or from the mutations in the growth hormone gene (GH1) in the PITUITARY GLAND. It is also known as Type I pituitary dwarfism. Human hypophysial dwarf is caused by a deficiency of HUMAN GROWTH HORMONE during development.


Adaptor Protein Complexes, Vesicular Transport

Vesicular Transport Adaptor Protein Complexes

Multisubunit protein complexes of adaptor proteins.


Dichloromethylene Biphosphonate
Clodronate Sodium
Clodronate
Dichloromethylene Diphosphonate
Bonefos
Cl2MDP
Clodronate Disodium
Dichloromethanediphosphonate
Dichloromethylenebisphosphonate
Dichloromethanediphosphonic Acid
Clodronic Acid
Dichloromethane Diphosphonate

A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.


Sarcoma, Cerebellar, Circumscribed Arachnoidal

Arachnoidal Cerebellar Sarcoma, Circumscribed

A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)


Laboratory Examinations and Diagnoses
Clinical Laboratory Techniques
Laboratory Techniques, Clinical
Clinical Laboratory Testings
Diagnosis, Laboratory
Clinical Laboratory Diagnoses
Laboratory Diagnosis
Diagnoses and Laboratory Examinations
Clinical Laboratory Tests

Techniques used to carry out clinical investigative procedures in the diagnosis and therapy of disease.


An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.


Permafrost Soil
Permafrost Region
Permafrost
Permafrost Zone

Perennially frozen layer of soil below the surface in tundra.


Hepatitis B Virus, Ground Squirrel
Ground Squirrel Hepatitis Virus
Orthohepadnavirus
Ground Squirrel Hepatitis B Virus

A genus of HEPADNAVIRIDAE causing HEPATITIS in humans, woodchucks (HEPATITIS B VIRUS, WOODCHUCK) and ground squirrels. Hepatitis B virus is the type species.


Periplaneta americana
Periplaneta
American Cockroaches
American Cockroach

A genus in the family Blattidae containing several species, the most common being P. americana, the American cockroach.


Infectious Enteritis Virus, Feline
Feline Parvovirus
Panleukopenia Virus of Cats
Feline Infectious Enteritis Virus
Parvovirus, Feline
Feline Panleukopenia Virus
FPLV

A species of PARVOVIRUS infecting cats with a highly contagious enteric disease. Host range variants include mink enteritis virus, canine parvovirus (PARVOVIRUS, CANINE), and raccoon parvovirus. After infecting their new hosts, many of these viruses have further evolved and are now considered distinct species.


Biofiltration, Acetate-Free
Hemodiafiltration
Acetate-Free Biofiltration

The combination of hemodialysis and hemofiltration either simultaneously or sequentially. Convective transport (hemofiltration) may be better for removal of larger molecular weight substances and diffusive transport (hemodialysis) for smaller molecular weight solutes.


Idiopathic Hypertrophic Pyloric Stenosis

Narrowing of the pyloric canal due to HYPERTROPHY of the surrounding circular muscle. It is usually seen in infants or young children.


Virtual Reality, Instructional
Virtual Reality
Virtual Reality, Educational

Using computer technology to create and maintain an environment and project a user's physical presence in that environment allowing the user to interact with it.


A plant genus of the family MYRTACEAE that bears an edible fruit and contains guavin B and quercetin glycosides.


Tinnitus, Spontaneous Oto-Acoustic Emission

Spontaneous Oto-Acoustic Emission Tinnitus

A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.


Butyric Acid, Sodium Salt
Butanoic Acid
Magnesium Butyrate
Butyric Acid Magnesium Salt
Magnesium Dibutyrate
Butyric Acid
Sodium Butyrate

A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.


Intravaginal Administration
Administration, Intravaginal
Instillation, Vaginal
Vaginal Administration
Administration, Vaginal
Drug Administration, Vaginal
Vaginal Drug Administration

The insertion of drugs into the vagina to treat local infections, neoplasms, or to induce labor. The dosage forms may include medicated pessaries, irrigation fluids, and suppositories.


Bronchi
Secondary Bronchi
Primary Bronchus
Tertiary Bronchi
Tertiary Bronchus
Primary Bronchi
Secondary Bronchus

The larger air passages of the lungs arising from the terminal bifurcation of the TRACHEA. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into BRONCHIOLES and PULMONARY ALVEOLI.


Reductases Oxidase Oxidases Oxidoreductases Dehydrogenase Reductase Dehydrogenases

The class of all enzymes catalyzing oxidoreduction reactions. The substrate that is oxidized is regarded as a hydrogen donor. The systematic name is based on donor:acceptor oxidoreductase. The recommended name will be dehydrogenase, wherever this is possible; as an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor. (Enzyme Nomenclature, 1992, p9)


Transitional Disorders, Sleep-Wake
Jactatio Capitis Nocturna
Sleep Talking
Nocturnal Sleep Head Banging
Sleep-Wake Transition Disorders
Sleep Starts
Rhythmic Movement Disorders, Nocturnal
Nocturnal Leg Cramps
Transition Disorders, Sleep-Wake
Sleep-Wake Transitional Disorders
Somnolescent Starts
Movement Disorders, Rhythmic Nocturnal

Parasomnias characterized by behavioral abnormalities that occur during the transition between wakefulness and sleep (or between sleep and wakefulness).


Complexes composed of subunits of the different sarcoglycans. The sarcoglycan complex is a component of the DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX. Mutations abolishing the expression of sarcoglycans of the muscle sarcoglycan complex are associated with of LIMB-GIRDLE MUSCULAR DYSTROPHY.


Scolicides
Anticestodal Agents
Scolicidal Agents
Taeniacides

Agents used in the treatment of ECHINOCOCCOSIS, especially those that kill the hydatid cyst, or larvae, of ECHINOCOCCUS worms.


Salaries and Fringe Benefits
Salaries
Wages
Pay Equity
Paternity Benefits
Fringe Benefits

The remuneration paid or benefits granted to an employee.


Prevention, Primordial
Primordial Prevention
Primary Prevention
Prevention, Primary
Disease Prevention, Primary

Specific practices for the prevention of disease or mental disorders in susceptible individuals or populations. These include HEALTH PROMOTION, including mental health; protective procedures, such as COMMUNICABLE DISEASE CONTROL; and monitoring and regulation of ENVIRONMENTAL POLLUTANTS. Primary prevention is to be distinguished from SECONDARY PREVENTION and TERTIARY PREVENTION.


Gyno-Pervaryl 150
Gyno-Pevaril
Econazole
Ekonazole
Pevaryl
Gyno-Pevaryl
Econazole Nitrate

An imidazole derivative that is commonly used as a topical antifungal agent.


Surgery, Colposcopic
Surgical Procedures, Colposcopic
Colposcopic Surgery
Colposcopic Surgical Procedures
Colposcopy

The examination, therapy or surgery of the cervix and vagina by means of a specially designed endoscope introduced vaginally.


Corylus Filberts Hazelnuts Hazelnut Filbert


A carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON DISEASE.


Smilax ornata
Greenbrier
Sarsaparilla
Smilax
Zarzaparilla
Greenbriar
Jamaican Sarsaparilla

A plant genus of the family SMILACACEAE. Members contain smiglasides (phenylpropanoid glycosides) and steroidal saponins. Commercially it is sometimes adulterated with HEMIDESMUS, which would affect experimental results. Drinks called sarsaparilla and root beer have been prepared from the Smilaz ornata (Jamaican sarsaparilla) and SASSAFRAS.


AMP-Activated Protein Kinase alpha Subunits

AMP-Activated Protein Kinase gamma Subunits

AMP-Activated Protein Kinase beta Subunits

Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.


A stilbene and non-flavonoid polyphenol produced by various plants including grapes and blueberries. It has anti-oxidant, anti-inflammatory, cardioprotective, anti-mutagenic, and anti-carcinogenic properties. It also inhibits platelet aggregation and the activity of several DNA HELICASES in vitro.


Basement Lamina
Basement Membrane
Basal Lamina

A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.


The use of nails that are inserted into bone cavities in order to keep fractured bones together.


Heterocyclic Compounds with Four or More Rings

Heterocyclic Compounds with 4 or More Rings

A class of heterocyclic compounds that include four or more fused rings. Both aromatic or non-aromatic ring structures are included in this category.


Intellectual Disability
Mental Retardation, Psychosocial
Idiocy
Mental Retardation
Mental Deficiency
Deficiency, Mental
Intellectual Development Disorder
Disability, Intellectual
Retardation, Mental

Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)


A pyrrole and heptanoic acid derivative, HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITOR (statin), and ANTICHOLESTEREMIC AGENT that is used to reduce serum levels of LDL-CHOLESTEROL; APOLIPOPROTEIN B; and TRIGLYCERIDES. It is used to increase serum levels of HDL-CHOLESTEROL in the treatment of HYPERLIPIDEMIAS, and for the prevention of CARDIOVASCULAR DISEASES in patients with multiple risk factors.


Cardamine pratensis
Cardamine
Cress, Meadow
Cress, Bitter

A plant genus of the family BRASSICACEAE that is low-growing in damp meadows of the Northern Hemisphere and has pinnately divided leaves and small white to rose flowers.


Receptors, Opioid, mu
mu Receptors
mu Receptor
Receptors, Morphine
Opioid Receptors, mu
Receptors, mu
Morphine Receptor
mu Opioid Receptor
Receptors, mu Opioid
Morphine Receptors

A class of opioid receptors recognized by its pharmacological profile. Mu opioid receptors bind, in decreasing order of affinity, endorphins, dynorphins, met-enkephalin, and leu-enkephalin. They have also been shown to be molecular receptors for morphine.


Hereditary Oligophrenic Cerebello-Lental Degeneration

A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.


The family Sturnidae, in the order PASSERIFORMES. The starling family also includes mynahs and oxpeckers.


Cork Oak Tree
Quercus infectoria
Quercus ilex
Quercus suber
Oak Tree
Holly Oak
Quercus

A plant genus of the family FAGACEAE that is a source of TANNINS. Do not confuse with Holly (ILEX).


A carotenoid and red pigment produced by tomatoes, other red fruits and vegetables, and photosynthetic algae. It is a key intermediate in the biosynthesis of other carotenoids, and has antioxidant, anti-carcinogenic, radioprotective, and anti-inflammatory properties.


Gastrointestinal Hormones
Intestinal Hormones
Enteric Hormones

HORMONES secreted by the gastrointestinal mucosa that affect the timing or the quality of secretion of digestive enzymes, and regulate the motor activity of the digestive system organs.


T2 Phage
Coliphage T2
Phage T2
T4 Phage
Phage T4
Bacteriophage T2
Coliphage T4
Bacteriophage T4
Enterobacteria phage T4
Enterobacteria phage T2


Sub-Fertility, Male
Subfertility, Male
Infertility, Male
Sterility, Male

The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.


Phosphorus-31
White Phosphorus
Yellow Phosphorus
Black Phosphorus
Red Phosphorus
Phosphorus

A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.


Japanese Medaka
Oryziinae
Oryzias latipes
Japanese Rice Fish
Medaka
Medaka Killifish
Japanese Killifish
Killifish, Japanese
Oryzias

Common name for a species in the genus Oryzias.


Infections, Tick-Borne
Tick-Borne Diseases
Tick-Borne Infections

Bacterial, viral, or parasitic diseases transmitted to humans and animals by the bite of infected ticks. The families Ixodidae and Argasidae contain many bloodsucking species that are important pests of man and domestic birds and mammals and probably exceed all other arthropods in the number and variety of disease agents they transmit. Many of the tick-borne diseases are zoonotic.


Kimmelstiel-Wilson Syndrome
Intracapillary Glomerulosclerosis
Diabetic Glomerulosclerosis
Diabetic Kidney Disease
Diabetic Nephropathies
Nodular Glomerulosclerosis
Kimmelstiel-Wilson Disease
Glomerulosclerosis, Diabetic
Diabetic Nephropathy

KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.


Biosafety
Physical Containment
Biohazards Containment
Biological Containment
Containment of Biohazards
Containment, Biologic
Biohazard Containment

Physical and biological barriers against the spread of potentially hazardous biologically active agents such as bacteria, viruses, recombinant nucleotides, contaminated bio-specimens, etc. Typically involves the use of specialized equipment, facilities, procedures, professional personnel and established protocols.


Scheie's Syndrome
Mucopolysaccharidosis Type Ih S
Hurler-Scheie Syndrome
Gargoylism
Hurler's Disease
Mucopolysaccharidosis Type Is
alpha-L-Iduronidase Deficiency
Pfaundler-Hurler Syndrome
Mucopolysaccharidosis 5
Mucopolysaccharidosis Type I
Hurler's Syndrome
Mucopolysaccharidosis I
Mucopolysaccharidosis 1
Hurler Disease
Gargoylism, Hurler Syndrome
Mucopolysaccharidosis V
Hurler Syndrome
Mucopolysaccharidosis Type Ih
Lipochondrodystrophy
Mucopolysaccharidosis I-S
Scheie Syndrome

Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase (IDURONIDASE) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity from severe to mild: Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome (formerly mucopolysaccharidosis V). Symptoms may include DWARFISM; hepatosplenomegaly; thick, coarse facial features with low nasal bridge; corneal clouding; cardiac complications; and noisy breathing.


Miraa
Catha edulis
Khat
Qat Plant
Catha
Mairungi

A plant genus of the family CELASTRACEAE. The leafy stems of khat are chewed by some individuals for stimulating effect. Members contain ((+)-norpseudoephedrine), cathionine, cathedulin, cathinine & cathidine.


Consensus Development Conferences as Topic

Conferences, Consensus Development as Topic

Works that are about the concept of consensus development conferences, such as their general design or a means of scientific communication.


Pulmonary Emphysemas
Panlobular Emphysema
Centrilobular Emphysema
Emphysemas, Pulmonary
Panacinar Emphysema
Emphysema, Pulmonary
Centriacinar Emphysema
Focal Emphysema
Pulmonary Emphysema

Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.


Differentiation Antigens, B-Cell
B-Lymphocyte Differentiation Antigens
Antigens, Differentiation, B-Cell
Differentiation Antigens, B-Lymphocyte
Antigens, Differentiation, B-Lymphocyte
Antigens, Plasma Cell, PC-1
Leu Antigens, B-Lymphocyte
Antigens, Differentiation, B Lymphocyte
Plasma Cell Antigens PC-1
B-Cell Blast-2 Antigen
B-Cell Differentiation Antigens
Blast-2 Antigen, B-Cell

Membrane antigens associated with maturation stages of B-lymphocytes, often expressed in tumors of B-cell origin.


Orthodenticle Homolog Homeodomain Proteins

A family of VERTEBRATE homeodomain proteins that share homology with orthodenticle protein, Drosophila. They regulate GENETIC TRANSCRIPTION and play an important role in EMBRYONIC DEVELOPMENT of the BRAIN.


Curcuma
Curcuma zedoaria
Turmeric
Zedoary zedoaria
Curcuma longa
Tumeric

A plant genus of the family ZINGIBERACEAE that contains CURCUMIN and curcuminoids.


A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)


A plant genus of the family CRASSULACEAE. Some species in this genus are called stonecrop which is also a common name for RHODIOLA.


Phosphoinositide-3-Kinase, Regulatory Subunit 2

p110delta Subunit, Class Ia Phosphatidylinositol 3-Kinase

Class Ia Phosphatidylinositol 3-Kinase, p85beta Subunit

Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide

Phosphoinositide-3-Kinase, Regulatory Subunit 3

Class Ia Phosphatidylinositol 3-kinase, Regulatory, gamma Polypeptide

Class Ia Phosphatidylinositol 3-Kinase, p85alpha Subunit

Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide

p110beta Subunit, Class Ia Phosphatidylinositol 3-Kinase

p85alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase

Class Ia Phosphatidylinositol 3-Kinase, p110alpha Subunit

Class Ia Phosphatidylinositol 3-Kinase, p55alpha Subunit

p55gamma Subunit, Class Ia Phosphatidylinositol 3-Kinase

Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide

p50alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase

p85beta Subunit, Class Ia Phosphatidylinositol 3-Kinase

Class Ia Phosphatidylinositol 3-Kinase, p110beta Subunit

Class Ia Phosphatidylinositol 3-Kinase, p55gamma Subunit

Class Ia Phosphatidylinositol 3-Kinase, p110delta Subunit

Phosphoinositide-3-Kinase, Regulatory Subunit 1

Class Ia Phosphatidylinositol 3-kinase, Regulatory, alpha Polypeptide

Class Ia Phosphatidylinositol 3-Kinase, p50alpha Subunit

p110alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase

Class Ia Phosphatidylinositol 3-kinase, Regulatory, beta Polypeptide

p55alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase

A 50kDa variant protein resulting from alternatively-splicing of the phosphoinositide-3-Kinase, regulatory subunit 1mRNA.


A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.


Almitrine
Vectarion
Almitrine Dimesylate
Almitrine Monomesylate
Almitrine Bis(methanesulfonate)
Almitrine Bismesylate

A respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.


Adaptive Thermogenesis
Facultative Thermogenesis
Thermogenesis
Heat Production
Nonshivering Thermogenesis

The generation of heat in order to maintain body temperature. The uncoupled oxidation of fatty acids contained within brown adipose tissue and SHIVERING are examples of thermogenesis in MAMMALS.


Voltage-Gated Sodium Channel Type 3 alpha Subunit

Voltage-Gated Sodium Channel Type 3 Subunit alpha

A voltage-gated sodium channel subtype found in neuronal tissue that mediates the sodium ion PERMEABILITY of excitable membranes.


Bacterium-Host Interactions
Microbiota Host Interactions
Bacterial-Host Interactions
Microbe Host Interactions
Host Microbiota Interactions
Host Microbial Interactions
Virus Host Interactions
Viral-Host Interactions
Host Microbe Interactions
Host Bacteria Interactions
Host-Fungal Interactions
Bacteria Host Interactions
Host-Microbial Interface
Host Virus Interactions
Microbial Host Interactions

Interactions between a host and microbe or microbiota.


Lock Jaw
Masseter Spasm
Lockjaw
Trismus
Masseter Muscle Spasm

Spasmodic contraction of the masseter muscle resulting in forceful jaw closure. This may be seen with a variety of diseases, including TETANUS, as a complication of radiation therapy, trauma, or in association with neoplastic conditions.


Temaze
PMS-Temazepam
Norkotral Tema
Pronervon T
Oxydiazepam
Levanxol
Remestan
Gen-Temazepam
Novo-Temazepam
3-Hydroxydiazepam
Euhypnos
WY-3917
Tenox
Nu-Temazepam
Ro-5-5345
Apo-Temazepam
Normitab
Dasuen
SaH 47-603
Temtabs
Signopam
Normison
Methyloxazepam
Nocturne
Temazep Von Ct
Hydroxydiazepam
Restoril
Nortem
Planum
Temazepam

A benzodiazepine that acts as a GAMMA-AMINOBUTYRIC ACID modulator and anti-anxiety agent.


Deficiency Disease, Ganglioside Sialidase

Ganglioside Sialidase Deficiency Disease

A group of inherited metabolic diseases characterized by the accumulation of excessive amounts of acid mucopolysaccharides, sphingolipids, and/or glycolipids in visceral and mesenchymal cells. Abnormal amounts of sphingolipids or glycolipids are present in neural tissue. INTELLECTUAL DISABILITY and skeletal changes, most notably dysostosis multiplex, occur frequently. (From Joynt, Clinical Neurology, 1992, Ch56, pp36-7)


Dental Care for Handicapped
Dentistry for Handicapped
Dental Care for Disabled
Dentistry for Disabled

Dental care for the emotionally, mentally, or physically disabled patient. It does not include dental care for the chronically ill ( = DENTAL CARE FOR CHRONICALLY ILL).


Hypophyseal Disorders
Pituitary Disorders
Pituitary Gland Diseases
Anterior Pituitary Diseases
Posterior Pituitary Diseases
Adenohypophyseal Diseases
Neurohypophyseal Diseases
Pituitary Diseases

Disorders involving either the ADENOHYPOPHYSIS or the NEUROHYPOPHYSIS. These diseases usually manifest as hypersecretion or hyposecretion of PITUITARY HORMONES. Neoplastic pituitary masses can also cause compression of the OPTIC CHIASM and other adjacent structures.


Second Opinion
Hospital Referral
Health Service Gatekeepers
Referral
Gatekeepers, Health Service
Consultation and Referral
Hospital Referrals
Referrals, Hospital
Referral and Consultation
Consultation
Referral, Hospital

The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.


Typing, Bacterial
Typing Technic, Bacterial
Techniques, Bacterial Typing
Technic, Bacterial Typing
Technique, Bacterial Typing
Bacteriocin Typing
Bacterial Typing
Bacterial Typing Technics
Bacterial Typing Technique
Technics, Bacterial Typing
Typing Techniques, Bacterial
Bacterial Typing Technic
Bacterial Biotyping
Typing Technique, Bacterial
Bacterial Typing Techniques
Biotyping, Bacterial
Typing Technics, Bacterial

Procedures for identifying types and strains of bacteria. The most frequently employed typing systems are BACTERIOPHAGE TYPING and SEROTYPING as well as bacteriocin typing and biotyping.


Skull Fracture, Depressed
Skull Fracture, Compound Depressed
Compound Depressed Skull Fracture
Compound Depressed Skull Fractures
Skull Fractures, Compound Depressed

A skull fracture characterized by inward depression of a fragment or section of cranial bone, often compressing the underlying dura mater and brain. Depressed cranial fractures which feature open skin wounds that communicate with skull fragments are referred to as compound depressed skull fractures.


Adenosine Diphosphate Receptor Antagonists

Compounds that bind to and block the stimulation of PURINERGIC P2Y RECEPTORS. Included under this heading are antagonists for specific P2Y receptor subtypes.


An acetamide derivative that acts as a blocker of VOLTAGE-GATED SODIUM CHANNELS. It is used as an anticonvulsant, for adjunctive or monotherapy, in the treatment of PARTIAL SEIZURES.


HSIL, High-Grade Squamous Intraepithelial Lesions

LSIL, Atypical Squamous Cells Cannot Exclude HSIL

LSIL, Low-Grade Squamous Intraepithelial Lesions

A cytological test finding that shows abnormal lesions of SQUAMOUS EPITHELIAL cells.


Weill-Marchesani Syndrome, Autosomal Dominant

Weill-Marchesani Syndrome, Autosomal Recessive

The autosomal dominant form of Weill-Marchesani syndrome is associated with Adamts10 gene mutations.


Cell Cycle Checkpoint Genes
cdc Genes
Genes, Cell Division Cycle
Cell Cycle Genes
Genes, cdc
Cell Division Cycle Genes
Checkpoint Genes, Cell Cycle

A set of genes that stop cell division if events in the CELL CYCLE have not been completed properly.


Receptors, Neuromodulators
Neurohumor Receptors
Neuromodulator Receptors
Receptors, Neuroregulators
Neurotransmitter Receptor
Synaptic Receptors
Receptors, Neurotransmitter
Receptors, Neurotransmitters
Neuromediator Receptors
Neuromodulator Receptor
Neuromediator Receptor
Receptors, Neurohumor
Neuroregulator Receptors
Neuroregulator Receptor
Receptors, Neuromediators
Receptors, Synaptic

Cell surface receptors that bind signalling molecules released by neurons and convert these signals into intracellular changes influencing the behavior of cells. Neurotransmitter is used here in its most general sense, including not only messengers that act to regulate ion channels, but also those which act on second messenger systems and those which may act at a distance from their release sites. Included are receptors for neuromodulators, neuroregulators, neuromediators, and neurohumors, whether or not located at synapses.


Educational Needs Assessment
Determination of Health Care Needs
Needs Assessment
Determination of Healthcare Needs
Assessment of Health Care Needs
Assessment of Healthcare Needs

Systematic identification of a population's needs or the assessment of individuals to determine the proper level of services needed.


Function Tests, Pulmonary
Respiratory Function Tests
Pulmonary Function Tests
Pulmonary Function Test
Test, Pulmonary Function
Lung Function Tests
Tests, Pulmonary Function
Function Test, Pulmonary

Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.


Ocular Physiologic Process
Ocular Physiological Processes
Ocular Physiological Concepts
Ocular Physiological Process
Eye Physiology
Physiology, Ocular
Visual Physiology
Ocular Physiology
Ocular Physiological Phenomenon
Ocular Physiological Phenomena
Ocular Physiologic Processes
Physiology of the Eye

Processes and properties of the EYE as a whole or of any of its parts.


Clathrin Assembly Protein Complex alpha Subunits

A family of large adaptin protein subunits of approximately 100 kDa in size. They have been primarily found as components of ADAPTOR PROTEIN COMPLEX 2.


Convulsofin
Valproate Sodium
Depakine
Sodium Valproate
Depakene
Valproate
Magnesium Valproate
Depakote
Valproate Calcium
Divalproex
Ergenyl
2-Propylpentanoic Acid
Dipropyl Acetate
Propylisopropylacetic Acid
Valproic Acid, Sodium Salt (2:1)
Semisodium Valproate
Vupral
Calcium Valproate
Valproic Acid
Divalproex Sodium

A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.


Receptor, Vascular Endothelial Cell Growth Factor

Vascular Endothelial Cell Growth Factor Receptor

Receptors, Vascular Endothelial Growth Factor

Vascular Endothelial Growth Factor Receptor

A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.


Periodontitis, Apical, Chronic Nonsuppurative

Periapical Periodontitis, Chronic Nonsuppurative

Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.


Transcription, Medical
Medical Records
Medical Transcription
Health Diaries
Records, Medical

Recording of pertinent information concerning patient's illness or illnesses.


Quararibea Durio Durian Pachira Ochroma Bombacaceae Balsa

A plant family of the order Malvales, subclass Dilleniidae, class Magnoliopsida of tropical trees.


Hearing Loss, Sudden
Deafness, Sudden
Sudden Deafness
Sudden Hearing Loss

Complete sensorineural hearing loss which develops suddenly over a period of hours or a few days.


Hereditary Angioedema Type II
Deficiency of C1 Esterase Inhibitor
Hereditary Angioedema Type I
C1 Esterase Inhibitor, Deficiency Of
Hereditary Angioedema Type 1
Hereditary Angioedema Types I and II
Angioedema, Hereditary, Types I and II
Angioedema, Hereditary, Type II
Angioedema, Hereditary, Type I

Forms of hereditary angioedema that occur due to mutations in the gene for COMPLEMENT C1 INHIBITOR PROTEIN. Type I hereditary angioedema is associated with reduced serum levels of complement C1 inhibitor protein. Type II hereditary angioedema is associated with the production of a non-functional complement C1 inhibitor protein.


Endochondral Ossification
Ossification, Physiological
Physiologic Ossification
Ossification
Osteoclastogenesis
Osteogenesis
Bone Formation
Ossification, Physiologic

The process of bone formation. Histogenesis of bone including ossification.


Nodular Elastoidosis
Facial Dermatosis
Facial Dermatoses
Favre-Racouchot Syndrome
Nodular Elastosis


Elocon
Sch 32088
Mometasone Furoate Monohydrate
Mometasone
Asmanex Twisthaler
Rinelon
Nasonex
Mometasone Furoate
Sch-32088
Asmanex

A pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for skin disorders.


An anti-CTLA-4 ANTIGEN monoclonal antibody initially indicated for the treatment of certain types of metastatic MELANOMA. Its mode of actions may include blocking of CTLA-4 mediated inhibition of CYTOTOXIC T LYMPHOCYTES, allowing for more efficient destruction of target tumor cells.


An androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant PROSTATE CANCER.


Self Esteem
Self-Perception
Self Concept
Self Confidence
Self Perception


Startle Gating
Sensorimotor Gating
Sensory Filtering
Sensory Gating
Auditory Sensory Gating
Acoustic Startle Gating

The ability of the BRAIN to suppress neuronal responses to external sensory inputs, such as auditory and visual stimuli. Sensory filtering (or gating) allows humans to block out irrelevant, meaningless, or redundant stimuli.


Delay Discounting
Intertemporal Preferences
Intertemporal Decision-Making
Intertemporal Decision Making
Delayed Gratification
Temporal Discounting
Deferred Gratification

The ability to resist the temptation for an immediate reward and wait for a later reward.


Cold-Induced Autoinflammatory Syndrome, Familial

Chronic, Infantile, Neurological, Cutaneous, Articular Syndrome

Chronic Neurologic, Cutaneous, and Articular Syndrome

Chronic Infantile Neurological, Cutaneous, and Articular Syndrome

Familial Cold Autoinflammatory Syndrome 1

Neonatal Onset Multisystem Inflammatory Disease

Familial Cold-Induced Autoinflammatory Syndrome

Infantile Onset Multisystem Inflammatory Disease

Chronic Neurologic Cutaneous and Articular Syndrome

Multisystem Inflammatory Disease, Neonatal-Onset

Chronic Infantile Neurologic, Cutaneous, and Articular Syndrome

A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ damage. The atypical hives do not involve T-cell or autoantibody. Cryopyrin-associated periodic syndrome includes three previously distinct disorders: Familial cold autoinflammatory syndrome; Muckle-Wells Syndrome; and CINCA Syndrome, that are now considered to represent a disease continuum, all caused by NLRP3 PROTEIN mutations.


Kasaba
Arrowroot, Brazilian
Cassava
Manihot esculenta
Manihot
Brazilian Arrowroot
Tapioca
Manioc

A plant genus of the family EUPHORBIACEAE that is perennial with conspicuous, almost palmate leaves like those of RICINUS but more deeply parted into five to nine lobes. It is a source of a starch after removal of the cyanogenic glucosides. The common name of Arrowroot is also used with Maranta (MARANTACEAE). The common name of yuca is also used for YUCCA.


One Medicine Initiative
One Health Concept
One Health
One Health Initiative

An integrative effort of multiple disciplines working collaboratively and locally, nationally, and globally in all aspects of health care for humans, animals, and the environment.


Elvitegravir-Cobicistat-Emtricitabine-Tenofovir Disoproxil Fumarate Drug Combination

Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate Drug Combination

Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination

A pharmaceutical preparation of the ANTI-HIV AGENTS elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate that is used in the treatment of HIV INFECTIONS.


Computer-Aided Manufacturing
Computer-Assisted Design
CAD-CAM
Computer-Aided Design
Computer-Assisted Manufacturing

The use of computers for designing and/or manufacturing of anything, including drugs, surgical procedures, orthotics, and prosthetics.


Cerebellar Gait
Gait Ataxia
Ataxia of Gait
Gait Ataxia, Sensory
Cerebellar Gait Ataxia

Impairment of the ability to coordinate the movements required for normal ambulation (WALKING) which may result from impairments of motor function or sensory feedback. This condition may be associated with BRAIN DISEASES (including CEREBELLAR DISEASES and BASAL GANGLIA DISEASES); SPINAL CORD DISEASES; or PERIPHERAL NERVOUS SYSTEM DISEASES.


Progressive Intracranial Occlusive Arteropathy (Moyamoya)

A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.


Glia Maturation Factor
GMF-beta
GMFbeta
Glial Maturation Factor
GMF
Glia Maturation Factor beta
Glia Maturation Factor-beta

A factor identified in the brain that influences the growth and differentiation of NEURONS and NEUROGLIA. Glia maturation factor beta is the 17-kDa polypeptide product of the GMFB gene and is the principal component of GLIA MATURATION FACTOR.


Transforming Growth Factor beta 1 Latency Associated Peptide

A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.


ESWL (Extracorporeal Shockwave Lithotripsy)

The destruction of a calculus of the kidney, ureter, bladder, or gallbladder by physical forces, including crushing with a lithotriptor through a catheter. Focused percutaneous ultrasound and focused hydraulic shock waves may be used without surgery. Lithotripsy does not include the dissolving of stones by acids or litholysis. Lithotripsy by laser is LITHOTRIPSY, LASER.


Anti-Cyclic Citrullinated Protein Antibodies

Autoantibodies to citrullinated-peptides and proteins.


An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.


Moricizine Hydrochloride
Moracizin
EN-313
Moracizine
Ethmozin
Moricizine
Etmozin
Ethmozine

An antiarrhythmia agent used primarily for ventricular rhythm disturbances.


Hexanoic Acids
Caproates
Caproic Acids
Hexanoates
Caproic Acid Derivatives
Hexanoic Acid Derivatives

Derivatives of caproic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a carboxy terminated six carbon aliphatic structure.


Microfluidic Devices
Lab-On-A-Chip Devices
Microchip Analytical Devices
Microfluidic Lab-On-A-Chip
Nanochip Analytical Devices
Microfluidic Microchips

Microdevices that combine microfluidics technology with electrical and/or mechanical functions for analyzing very small fluid volumes. They consist of microchannels etched into substrates made of silicon, glass, or polymer using processes similar to photolithography. The test fluids in the channels can then interact with different elements such as electrodes, photodetectors, chemical sensors, pumps, and valves.


Proglucagon
Pro-Glucagon
Pre-Proglucagons
Glucagon Precursors
Glucagon Precursor
Preproglucagons
Preproglucagon

The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE PEPTIDES. Proglucagon is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence. Proglucagon is expressed in the PANCREAS; INTESTINES; and the CENTRAL NERVOUS SYSTEM. Posttranslational processing of proglucagon is tissue-specific yielding numerous bioactive peptides.


A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.


An organoplatinum compound that possesses antineoplastic activity.


A phylum of unicellular parasitic EUKARYOTES characterized by the presence of complex apical organelles generally consisting of a conoid that aids in penetrating host cells, rhoptries that possibly secrete a proteolytic enzyme, and subpellicular microtubules that may be related to motility.


Light-Dark Cycle
Photoperiod
Dark-Light Cycle
Daylight Cycle
Light Cycle

The time period of daily exposure that an organism receives from daylight or artificial light. It is believed that photoperiodic responses may affect the control of energy balance and thermoregulation.


Failure, Dental Restoration
Restoration Failure, Dental
Prosthesis Failure, Dental
Restoration Failures, Dental
Failure, Dental Prosthesis
Prosthesis Failures, Dental
Failures, Dental Restoration
Dental Prosthesis Failure
Dental Prosthesis Failures
Dental Restoration Failure
Dental Restoration Failures
Failures, Dental Prosthesis

Inability or inadequacy of a dental restoration or prosthesis to perform as expected.


Neurotrophic Tyrosine Kinase, Receptor-related Proteins

Receptor Tyrosine Kinase-like Orphan Receptors

Receptor Tyrosine Kinase-like Orphan Receptor 2

Receptor Tyrosine Kinase-like Orphan Receptor 1

A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.


H(+)-Transporting ATP Synthase, Acyl-Phosphate-Linked

The catalytic sector of proton-translocating ATPase complexes. It contains five subunits named alpha, beta, gamma, delta and eta.


Bean, African Yam
Yam Bean, African
Sphenostylis stenocarpa
Sphenostylis

A plant genus of the family FABACEAE that contains LECTINS and raffinose oligosaccharides.


Multiple Tumor-Associated Chromosome Region 1 Genes

Tumor suppressor gene located in the 11p13 region on the short arm of human chromosome 11. The absence of this gene is associated with the formation of Wilms tumor. It encodes several isoforms that are zinc finger containing transcription factors involved in both transactivation and repression, and are critical for normal development and function of the urogenital tract.


Animal Hypnosis
Hypnosis, Animal
Immobility Response, Tonic
Immobilization, Tonic
Death Feigning
Tonic Immobilization

An induced response to threatening stimuli characterized by complete loss of muscle strength.


Butapyrazole Fenilbutazon Butazolidin Phenylbutazone Diphenylbutazone Butadione Butacote Butadion Butapirazol

A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.


The main trunk of the systemic arteries.


Cholangitis, Chronic Nonsuppurative Destructive

FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.


Estradiol Dehydrogenase
17 beta-Estradiol Dehydrogenase
Estradiol 17 beta-Dehydrogenase
Estradiol Dehydrogenases
Estradiol 17 alpha-Dehydrogenase

Enzymes that catalyze the oxidation of estradiol at the 17-hydroxyl group in the presence of NAD+ or NADP+ to yield estrone and NADH or NADPH. The 17-hydroxyl group can be in the alpha- or beta-configuration. EC 1.1.1.62


Cellular senescence during AGING or due to extended passages of normal cells in culture and that is triggered by the DNA damage-response to TELOMERE SHORTENING or by repeated exposure to stress signals.


Class I human histocompatibility (HLA) surface antigens encoded by alleles on locus B of the HLA complex. The HLA-G antigens are considered non-classical class I antigens due to their distinct tissue distribution which differs from HLA-A; HLA-B; and HLA-C antigens. Note that several isoforms of HLA-G antigens result from alternative splicing of messenger RNAs produced from the HLA-G*01 allele.


Vincrisul
Vincristin Bristol
Farmistin
Citomid
Onkocristin
Vintec
Vincasar
Oncovin
Leurocristine
Vincristin medac
Vincristine Sulfate
Oncovine
Vincristine
cellcristin
Vincasar PFS

An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)


Coronary Arteriosclerosis
Coronary Atherosclerosis
Atherosclerosis, Coronary
Coronary Artery Disease
Arteriosclerosis, Coronary

Thickening and loss of elasticity of the CORONARY ARTERIES, leading to progressive arterial insufficiency (CORONARY DISEASE).