Bartonella bacilliformis Infection
Carrion Disease
Verruga Peruana
Bartonella Infections
Oroya Fever
Rochalimaea Infections
Carrion's Disease
Infections, Bartonella
Infections, Rochalimaea
Bartonellosis

Infections by the genus BARTONELLA. Bartonella bacilliformis can cause acute febrile anemia, designated Oroya fever, and a benign skin eruption, called verruga peruana. BARTONELLA QUINTANA causes TRENCH FEVER, while BARTONELLA HENSELAE is the etiologic agent of bacillary angiomatosis (ANGIOMATOSIS, BACILLARY) and is also one of the causes of CAT-SCRATCH DISEASE.


Sodium-driven chloride bicarbonate exchanger

Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 7

Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 5

Electroneutral Sodium Bicarbonate Exchanger 1

Electrogenic Sodium Bicarbonate Cotransporter 4

Electrogenic Sodium Bicarbonate Cotransporter 1

Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4

Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8

Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 10

Electroneutral Na(+)-Driven Cl-HCO3 Exchanger

electrogenic sodium-coupled bicarbonate transporters (SLC4A4 and 5); electroneutral sodium-coupled bicarbonate transporters (SLC4A7, 8 and 10)


Asialoglycoprotein Receptor
Asialoorosomucoid-Binding Protein
Asialoglycoprotein Receptors
Liver Carbohydrate-Binding Protein
ASGP-R
Receptor, Asialoglycoprotein
Hepatic Asialoglycoprotein Receptor
Receptor, Asialoorosomucoid
Hepatic Lectin
Asialoorosomucoid Receptor
Asialoorosomucoid Receptors

Asialoglycoprotein receptor found in liver.


Examiners, Medical
Medical Examiners
Medical Examiners and Coroners
Coroners
Medical Examiner
Examiner, Medical
Coroners and Medical Examiners

Physicians appointed to investigate all cases of sudden or violent death.


Herpesvirus 2, Ateline
Ateline Herpesvirus 2
Herpesvirus 2, Equid
Herpesvirus 2 (gamma), Ateline
Murine herpesvirus 68
Herpesvirus 4, Murid
Mouse herpesvirus strain 68
Herpesvirus Ateles
Equid Herpesvirus 2
Rhadinovirus
Equine Herpesvirus 2
Murid Herpesvirus 4

A genus of the family HERPESVIRIDAE, subfamily GAMMAHERPESVIRINAE, infecting New World primates and other species. HERPESVIRUS 2, SAIMIRIINE is the type species.


Animal Nutritional Sciences
Veterinary Nutrition Sciences
Animal Nutrition Sciences
Nutritional Sciences, Veterinary
Veterinary Nutritional Sciences
Nutritional Sciences, Animal

The study of NUTRITION PROCESSES, as well as the components of food, their actions, interaction, and balance in relation to health and disease in animals.


Genes, Essential
Genes, House-keeping
Genes, Housekeeping

Constitutively and evenly expressed genes involved in routine cellular metabolisms.


Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.


Laser-Doppler Velocimetry
Doppler-Laser Flowmetry
Flowmetry, Laser-Doppler
Laser-Doppler Flowmetry
Velocimetry, Laser-Doppler

A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.


Derivatives of oxazolidin-2-one. They represent an important class of synthetic antibiotic agents.


C3-C5 Convertase
C3 Activator
Complement C5 Convertases
C5 Convertase
Complement 5 Convertase
Complement 3 Convertase
Complement C3-C5 Convertases
C 3 Convertase
C5 Cleaving Enzyme
C3 Convertase
Complement C3 Convertases

Serine proteases that cleaves C3 at the carboxyl of Arg-77 of the alpha-chain to yield COMPLEMENT 3A and COMPLEMENT 3B in either the classical or the alternative pathways of COMPLEMENT ACTIVATION.


Metolazone Zaroxolyn SR-720-22 Microx Diulo Mykrox

A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.


CSF Hypovolemia
Intracranial Hypotension
Intracranial Hypotension, Secondary
Intracranial Hypotension, Essential
Intracranial Hypotension, Spontaneous
Cerebrospinal Fluid Hypovolemia

Reduction of CEREBROSPINAL FLUID pressure characterized clinically by ORTHOSTATIC HEADACHE and occasionally by an ABDUCENS NERVE PALSY; HEARING LOSS; NAUSEA; neck stiffness, and other symptoms. This condition may be spontaneous or secondary to CEREBROSPINAL FLUID LEAK; SPINAL PUNCTURE; NEUROSURGICAL PROCEDURES; DEHYDRATION; UREMIA; trauma (see also CRANIOCEREBRAL TRAUMA); and other processes. Chronic hypotension may be associated with subdural hematomas (see HEMATOMA, SUBDURAL) or hygromas. (From Semin Neurol 1996 Mar;16(1):5-10; Adams et al., Principles of Neurology, 6th ed, pp637-8)


A species of ORBIVIRUS infecting cattle and sheep. It is transmitted by culicine mosquitoes and gnats (CULICOIDES).


Ependymoma
Ependymoma, Myxopapillary
Clear Cell Ependymoma
Anaplastic Ependymoma
Cellular Ependymoma
Papillary Ependymoma
Ependymoma, Papillary

Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)


Mitogen-Activated Protein Kinase Kinase Kinases

Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).


Progressive Ossifying Myositis
Myositis Ossificans
Myositis Ossificans Progressiva
Fibrodysplasia Ossificans Progressiva
Progressive Myositis Ossificans

A disease characterized by bony deposits or the ossification of muscle tissue.


Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18

Human Papillomavirus Vaccine L1, Type 6,11,16,18

A vaccine containing L1 capsid proteins from four types of HPV (ALPHAPAPILLOMAVIRUS), types 6, 11, 16 and 18 that is used to prevent infections from HUMAN PAPILLOMAVIRUSES of these subtypes.


Folithion
Nitrophos
Methylnitrophos
Metathion
Sumithione
Fenitrothion
Sumithion
Agria 1050

An organothiophosphate cholinesterase inhibitor that is used as an insecticide.


Deficiency, Smooth Pursuit
Convergence Insufficiency
Smooth Pursuit Deficiency
Opsoclonus
Eye Motility Disorders
Internuclear Ophthalmoplegia
Paroxysmal Ocular Dyskinesia
Tendon Sheath Syndrome of Brown
Parinaud Syndrome
Eye Movement Disorders
Ocular Motility Disorders
Cyclophoria
Brown's Tendon Sheath Syndrome
Brown Tendon Sheath Syndrome
Spasm of Conjugate Gaze
Pseudoophthalmoplegia
Convergence Excess
Parinaud's Syndrome
Syndrome, Brown's Tendon Sheath
Ocular Torticollis
Skew Deviation

Disorders that feature impairment of eye movements as a primary manifestation of disease. These conditions may be divided into infranuclear, nuclear, and supranuclear disorders. Diseases of the eye muscles or oculomotor cranial nerves (III, IV, and VI) are considered infranuclear. Nuclear disorders are caused by disease of the oculomotor, trochlear, or abducens nuclei in the BRAIN STEM. Supranuclear disorders are produced by dysfunction of higher order sensory and motor systems that control eye movements, including neural networks in the CEREBRAL CORTEX; BASAL GANGLIA; CEREBELLUM; and BRAIN STEM. Ocular torticollis refers to a head tilt that is caused by an ocular misalignment. Opsoclonus refers to rapid, conjugate oscillations of the eyes in multiple directions, which may occur as a parainfectious or paraneoplastic condition (e.g., OPSOCLONUS-MYOCLONUS SYNDROME). (Adams et al., Principles of Neurology, 6th ed, p240)


A sulfone and pyridine derivative that acts as a cyclooxygenase-2 inhibitor. It is used as a NSAID for the treatment of pain associated with RHEUMATOID ARTHRITIS and ANKYLOSING SPONDYLITIS. It is also used for the short-term treatment of moderate postoperative dental pain.


Primate T-lymphotropic virus 2
PTLV-2
Simian T-lymphotropic virus-PP
STLV-PP
T-Lymphotropic Virus 2, Primate

A species in the family DELTARETROVIRUS, comprising strains from different host species but arising from the same geographic origin. They include HUMAN T-LYMPHOTROPIC VIRUS 2; SIMIAN T-LYMPHOTROPIC VIRUS 2; and Simian T-lymphotropic virus - PP.


Reverse-Phase Liquid Chromatography
Reverse-Phase Chromatography
Reversed-Phase Liquid Chromatography
Chromatography, Reversed-Phase Liquid
Reversed-Phase Chromatography
Chromatography, Reverse-Phase

A chromatography technique in which the stationary phase is composed of a non-polar substance with a polar mobile phase, in contrast to normal-phase chromatography in which the stationary phase is a polar substance with a non-polar mobile phase.


Benzatropine Methanesulfonate, Hydrochloride, (endo)-Isomer

Benzatropine Methanesulfonate, Hydrobromide, (endo)-Isomer

A centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine.


Instability, Joint
Laxity, Joint
Hypermobility, Joint
Joint Instability

Lack of stability of a joint or joint prosthesis.


Capsella bursa-pastoris
Shepherds Purse
Shepherd's Purse
Capsella


Cedar, Western Red
Thuja occidentalis
Biota orientalis
Arbor Vitae
Thuja orientalis
Thuja
Thuja plicata


External Compression Syndrome, Ulnar Nerve

Ulnar Nerve External Compression Syndrome

Ulnar neuropathies caused by mechanical compression of the nerve at any location from its origin at the BRACHIAL PLEXUS to its terminations in the hand. Common sites of compression include the retroepicondylar groove, cubital tunnel at the elbow (CUBITAL TUNNEL SYNDROME), and Guyon's canal at the wrist. Clinical features depend on the site of injury, but may include weakness or paralysis of wrist flexion, finger flexion, and ulnar innervated intrinsic hand muscles, and impaired sensation over the ulnar aspect of the hand, fifth finger, and ulnar half of the ring finger. (Joynt, Clinical Neurology, 1995, Ch51, p43)


Physicochemical Phenomenon
Physical Chemistry Processes
Physicochemical Process
Physicochemical Concepts
Chemical Concepts
Chemical Processes
Chemical Process
Physicochemical Phenomena
Physical Chemistry Process
Physicochemical Processes
Chemical Phenomenon
Physical Chemistry Concepts
Physical Chemistry Phenomena
Chemical Phenomena

The physical phenomena and properties underlying the structure of atoms and molecules, and their reaction and interaction processes.


Surface Tension
Interfacial Force
Interfacial Tension

Surface tension of the surfaces at the boundary between two immiscible liquids.


Enokitake
Flammulina
Flammulina velutipes
Enoki Mushroom

A genus of mushrooms in the family Tricholomataceae, whose species are characterized by a slimy cap (FRUITING BODIES, FUNGAL).


Glutaredoxin 1
Glutaredoxins
Thioltransferase
Glutaredoxin 5
TTase-1
Thioltransferase-1
Glutaredoxin 3
Glutaredoxin 2
Glutaredoxin

A family of thioltransferases that contain two active site CYSTEINE residues, which either form a disulfide (oxidized form) or a dithiol (reduced form). They function as an electron carrier in the GLUTHIONE-dependent synthesis of deoxyribonucleotides by RIBONUCLEOTIDE REDUCTASES and may play a role in the deglutathionylation of protein thiols. The oxidized forms of glutaredoxins are directly reduced by the GLUTATHIONE.


Euphorbia
Euphorbia hirta
Spurge
Chamaesyce hirta

A large plant genus of the family EUPHORBIACEAE, order Euphorbiales, subclass Rosidae. They have a milky sap and a female flower consisting of a single pistil surrounded by numerous male flowers of one stamen each. Euphorbia hirta is rarely called milkweed but that name is normally used for ASCLEPIAS.


Hemoglobin, Sickle
Deoxyhemoglobin S
Hemoglobin SS
Hemoglobin S
Deoxygenated Sickle Hemoglobin

An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.


An oxazolidinone and acetamide derived ANTI-BACTERIAL AGENT and PROTEIN SYNTHESIS INHIBITOR that is used in the treatment of GRAM-POSITIVE BACTERIAL INFECTIONS of the skin and respiratory tract.


Insurance, Health, Catastrophic
Medical Insurance, Major
Catastrophic Health Insurance
Major Medical Insurance
Comprehensive Health Insurance
Insurance, Major Medical

Insurance providing a broad range of medical services and supplies, when prescribed by a physician, whether or not the patient is hospitalized. It frequently is an extension of a basic policy and benefits will not begin until the basic policy is exhausted.


Pericardial Cavity
Pericardial Space
Epicardium
Visceral Pericardium
Parietal Pericardium
Serous Pericardium
Fibrous Pericardium
Pericardium

A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.


B-Lymphocyte kappa-Chain Gene Rearrangement

Gene Rearrangement, B-Lymphocyte, Light Chain

B-Lymphocyte Light Chain Gene Rearrangement

B Lymphocyte Light Chain Gene Rearrangement

B-Lymphocyte lambda-Chain Gene Rearrangement

Ordered rearrangement of B-lymphocyte variable gene regions coding for the kappa or lambda IMMUNOGLOBULIN LIGHT CHAINS, thereby contributing to antibody diversity. It occurs during the second stage of differentiation of the IMMATURE B-LYMPHOCYTES.


Cefamezine
Cefamedin
Cephamezine
Kefzol
Sodium Cephazolin
Cefazolin
Gramaxin
Cephazolin
Totacef
Cefazolin Sodium
Cephazolin Sodium
Ancef

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.


Base Composition
GC Composition
G+C Content
GC Content
G+C Composition
Guanine + Cytosine Content
Guanine + Cytosine Composition
Base Ratio

The relative amounts of the PURINES and PYRIMIDINES in a nucleic acid.


Cefsulodin Sodium
Pyocefal
CGP-7174-E
Cefsulodin
Abbott 46811
Cefsulodin Monosodium Salt
Monaspor
SCE-129

A pyridinium-substituted semisynthetic, broad-spectrum antibacterial used especially for Pseudomonas infections in debilitated patients.


Disopyramide, L-Tartrate (1:1), (S)-Isomer

Disopyramide, D-Tartrate (1:1), (S)-Isomer

Disopyramide, L-Tartrate (1:1), (R)-Isomer

Disopyramide Phosphate (1:1), (+-)-Isomer

Disopyramide Phosphate (1:1), (S)-Isomer

Disopyramide, L-Tartrate (1:2), (+-)-Isomer

Disopyramide Phosphate (1:1), (R)-Isomer

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.


Arches, Zygomatic
Malar Bone
Cheek Bone
Zygomatic Arches
Zygoma
Jugal Bone
Zygomatic Arch

Either of a pair of bones that form the prominent part of the CHEEK and contribute to the ORBIT on each side of the SKULL.


A pyrazine and boronic acid derivative that functions as a reversible PROTEASOME INHIBITOR. It is used as an ANTINEOPLASTIC AGENT in the treatment of MULTIPLE MYELOMA and MANTLE CELL LYMPHOMA.


Hepatopancreatic Ampulla
Greater Duodenal Papilla
Ampulla of Vater
Duodenal Papilla, Major
Vater's Ampulla

A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.


Hereditary Nonpolyposis Colorectal Neoplasms

Hereditary Nonpolyposis Colorectal Cancer

Colorectal Cancer Hereditary Nonpolyposis

Colorectal Neoplasms, Hereditary Nonpolyposis

HNPCC with no history of associated cancers.


GCAP Proteins
Guanylyl Cyclase-Activating Protein 1
Guanylate Cyclase-Activating Proteins
Guanylyl Cyclase-Activating Protein 3
Guanylyl Cyclase-Activating Protein 2
Guanylyl Cyclase Activating Proteins
Guanylate Cyclase-Activating Protein 2
Guanylate Cyclase-Activating Protein 3
GCAP2 Protein
GCAP1 Protein
GCAP3 Protein
Guanylate Cyclase-Activating Protein 1

Neuronal calcium sensor proteins that regulate the activation of membrane-bound GUANYLATE CYCLASE. They are primarily expressed in the RETINA where they play an important role in PHOTOTRANSDUCTION.


E-Cigarettes
Electronic Cigarettes
E-Cigs
Electronic Nicotine Delivery Systems

Devices or objects designed to provide NICOTINE in the form of an inhaled aerosol.


Recofol
ICI-35,868
2,6-Diisopropylphenol
Propofol Abbott
Propofol-Lipuro
Propofol Fresenius
Disoprivan
Ivofol
Diprivan
Aquafol
Fresofol
Propofol MCT
Propofol Rovi
Disoprofol
2,6-Bis(1-methylethyl)phenol
Propofol
ICI-35868

An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.


Plasminogen Activator, Tissue-Type
Tissue Plasminogen Activator
T-Plasminogen Activator
Activase
Tisokinase
Actilyse
Alteplase
Tissue-Type Plasminogen Activator
Lysatec rt-PA
Tissue Activator D-44
TTPA

A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.


Ulnar Trochlear Groove
Semilunar Notch
Ulna
Trochlear Notch
Ulnar Coronoid Process

A prominent depression in the upper extremity of the ulna between the coronoid process and the OLECRANON. It articulates with the distal end of the HUMERUS in the ELBOW JOINT.


Proendothelin (1-38)
Endothelin-1
Big Endothelin-1
Endothelin, Big
Big Endothelin
Endothelin Type 1
Proendothelin-1 Precursor
Preproendothelin
Preproendothelin-1

A 38 amino acid form of endothelin-1 that results from alternative processing of proendothelin-1.


Thiophanate-Methyl
Dimethylphenylene Bis-Thioallophanate
Mildothane
Thiophanate
Cercobin M-70

Nematocide used in livestock; also has fungicidal properties.


Wolfiporia
Tuckahoe Fungus
Wolfiporia extensa
Poria cocos
Fu Ling
Fuling
Wolfiporia cocos
Fu-Ling

The type species of Wolfiporia, formerly known as Poria cocos. It grows as a coconut-shaped sclerotium on the roots of pine trees and conifers.


Cariostatic Agents
Cariostatic Effect
Cariostatic Effects

Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed)


Septal Region
Septal Area
Septum of Brain
Paraterminal Body

GRAY MATTER structures of the telencephalon and LIMBIC SYSTEM in the brain, but containing widely varying definitions among authors. Included here is the cortical septal area, subcortical SEPTAL NUCLEI, and the SEPTUM PELLUCIDUM.


Naphuride
Suramin, Monosodium Salt
Naganol
Moranil
Suramin, Hexasodium Salt
Germanin
Naganin
Suramin
Suramin Sodium

A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.


Cancer of Digestive System
Digestive System Cancer
Cancer of the Digestive System
Neoplasms, Digestive System
Digestive System Neoplasms

Tumors or cancer of the DIGESTIVE SYSTEM.


Oral Mucositis
Oromucositis
Mucositis, Oral
Stomatitis


Collaborative Cross Mouse
Mouse, Diversity Outbred
Diversity Outbred Mouse
Collaborative Cross Mice
Mice, Diversity Outbred
Diversity Outbred Mice
Mice, Collaborative Cross
Mouse, Collaborative Cross

Inbred strain of mice derived from a subset of Collaborative Cross mice.


c-bcl-2 Proto-Oncogenes
bcl-2 Genes
Genes, bcl-2
c-bcl-2 Genes

The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.


Carbon Dioxide Partial Pressure Determination, Transcutaneous

Oxygen Partial Pressure Determination, Transcutaneous

The noninvasive measurement or determination of the partial pressure (tension) of oxygen and/or carbon dioxide locally in the capillaries of a tissue by the application to the skin of a special set of electrodes. These electrodes contain photoelectric sensors capable of picking up the specific wavelengths of radiation emitted by oxygenated versus reduced hemoglobin.


Elicitation of a rotatory nystagmus by stimulating the semicircular canals with water or air which is above or below body temperature. In warm caloric stimulation a rotatory nystagmus is developed toward the side of the stimulated ear; in cold, away from the stimulated side. Absence of nystagmus indicates the labyrinth is not functioning.


Sodium Biselenite
Selenous Acid, Disodium Salt
Disodium Selenite
Sodium Selenite Pentahydrate
Sodium Selenite
Selenous Acid Disodium Salt
Monosodium Selenite

The disodium salt of selenious acid. It is used therapeutically to supply the trace element selenium and is prepared by the reaction of SELENIUM DIOXIDE with SODIUM HYDROXIDE.


Microvasculature
Microvessels
Microvascular Network

The finer blood vessels of the vasculature that are generally less than 100 microns in internal diameter.


An estrogen antagonist that has been used in the treatment of breast cancer.


Government-Sponsored Programs
Government Programs
Government Sponsored Programs

Programs and activities sponsored or administered by local, state, or national governments.


Asfarviridae
Asfivirus
African Swine Fever-Like Viruses

The sole genus of ASFARVIRIDAE, containing a single species: AFRICAN SWINE FEVER VIRUS.


Infectious hypodermal and hematopoietic necrosis virus


Theiler's murine encephalomyelitis virus

Encephalomyelitis Virus, Murine, Theiler

Encephalomyelitis Virus, Human, Vilyuisk

A strain of THEILOVIRUS that can be divided into two biological subgroups which both infect mice. One causes an acute and fatal polioencephalomyelitis and the other causes a chronic persistent demyelinating infection of the white matter. (7th ICTV Report, p668-9)


Mineralocorticoids
Mineralocorticoid Effects
Mineralocorticoid Effect

A group of CORTICOSTEROIDS primarily associated with water and electrolyte balance. This is accomplished through the effect on ION TRANSPORT in renal tubules, resulting in retention of sodium and loss of potassium. Mineralocorticoid secretion is itself regulated by PLASMA VOLUME, serum potassium, and ANGIOTENSIN II.


New Zealand Rabbits
Chinchilla Rabbits
New Zealand White Rabbits
NZW Rabbits
Belgian Hare
Rabbits
Rabbit, Domestic
Oryctolagus cuniculus

This is a breed of rabbit, not to be confused with the rodent CHINCHILLA.


Aspects, Historical
History
Historical Aspects


Aquifers
Water Table
Underground Water
Underground Lakes
Groundwater
Ground-Water
Subterranean Lakes
Ground Water
Underground Streams

Liquid water present beneath the surface of the earth.


Renal Dialysis
Hemodialysis
Dialysis, Extracorporeal
Dialysis, Renal
Extracorporeal Dialysis

Removal of certain elements from the blood based on the difference in their rates of diffusion through a semipermeable membrane.


Abnormalities, Chromosomal
Cytogenetic Aberrations
Chromosome Abnormalities
Abnormalities, Autosome
Autosome Abnormalities
Chromosome Aberrations
Cytogenetic Abnormalities
Abnormalities, Chromosome
Chromosomal Aberrations

Abnormal number or structure of chromosomes. Chromosome aberrations may result in CHROMOSOME DISORDERS.


Models, Psychological
Model, Psychological
Models, Psychologic
Model, Mental
Models, Mental
Psychological Models

Cognitive representations of real, imaginary, or hypothetical situations or objects.


Poloxamer 2930
Poloxamer 213
Pluronic L-121
Poloxamer 338
Poloxalkol
Poloxamer 188
Pluronic F-68
Pluronics
Pluronic F-127
Pluronic L-81
Pluronic L-101
Poloxamers
Pluronic F68
Poloxamer 407
Pluronic F-108
Poloxamer

A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)


Lobule 9
Cerebellar Vermis
Lobule IX
Uvula of Cerebellum

A subregion of the CEREBELLAR CORTEX, located along the midsagittal plane of the CEREBELLUM.


Swineherd's Disease
Rice-Field Fever
Mud Fever
Canicola Fever
Leptospira Canicola Infection
Leptospirosis Canicola
Leptospira Infection
Leptospirosis
Stuttgart Disease
Cane-Cutter Fever

Infections with bacteria LEPTOSPIRA POMONA.


A broad-spectrum antimicrobial carboxyfluoroquinoline.


Inhibins, Testicular
Ovarian Inhibin
Testicular Inhibin
Inhibin-F
Female Inhibin
Inhibins, Female
Inhibins
Inhibin

Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively


Ionic monomeric contrast media. Usually the sodium or calcium salts are used for examination of the gall bladder and biliary tract. (From Martindale, The Extra Pharmacopoeia, 30th ed, p704)


Brain Connectomics
Connectome
Human Connectome
Connectome Mapping
Human Connectome Project
Connectomics


Serotonin 5-HT1A Receptor Agonists
5-HT1A Agonist
Serotonin 5-HT1B-D Agonists
Serotonin 5-HT1B Receptor Agonists
Serotonin 5-HT1 Receptor Agonists
5-HT1B-D Agonist
5-HT1 Agonist
5-HT1 Agonists
5-HT1B Agonist
Serotonin 5-HT1D Receptor Agonists
5-HT1D Agonist

Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT1 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT1 receptor subtypes.


Mammoths
Mammuthus
Woolly Mammoth
Mammuthus primigenius

An extinct genus of large mammals in the family Elephantidae that fed by grazing on low vegetation. Most died out at the end of the last ice age.


Intraoperative Blood Salvage
Post-Operative Blood Salvage
Intraoperative Blood Cell Salvage
Postoperative Blood Salvage
Operative Blood Salvage

Recovery of blood lost from surgical procedures, during the procedures, for reuse by the same patient in AUTOLOGOUS BLOOD TRANSFUSIONS.


Methylpromazine Variargil Trimeprazine Vallergan Nedeltran Panectyl Repeltin Théralène Spansule Isobutrazine Alimemazine

A phenothiazine derivative that is used as an antipruritic.


Pulsed Dye Lasers
Lasers, Tunable Dye
Lasers, Dye
Lasers, Pulsed Dye
Tunable Dye Lasers
Dye Lasers

Tunable liquid lasers with organic compounds (i.e., dye) which have a strong absorption band, used as the active medium. During emission, the dye has to be optically excited by another light source (e.g., another laser or flash lamp). The range of the emission wavelength may be anywhere from the ultraviolet to the near infrared (i.e., from 180 to 1100nm). These lasers are operated in continuous wave and pulsed modes. (UMDNS, 2005)


Methylscopolammonium Methylsulfate
N-Methylscopolamine Bromide
Ulix
N-Methylscine Methylsulfate
Hyoscine Methiodide
N-Methylscopolamine
Methscopolamine
DD-234
N-Methylscopolamine Methylchloride
N-Methylscopolamine Methylsulfate
N-Methylscopolamine Nitrate
Skopyl
Hyoscine Methobromide
Scopolamine Methylbromide
N-Methylscopolamine Iodide
Methylscopolamine Nitrate

A muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.


Collagen Type XIII, alpha1 Subunit
Collagen Type XIII, alpha1 Chain
Collagen Type XIII
Procollagen Type XIII
Type XIII Collagen
Collagen alpha1(XIII)
Type XIII Procollagen

A non-fibrillar collagen found as a ubiquitously expressed membrane- associated protein. Type XIII collagen contains both collagenous and non-collagenous domains along with a transmembrane domain within its N-terminal region.


Polar Bears
Giant Pandas
Grizzly Bears
Spectacled Bear
Ursus
Pandas, Greater
Ailuropoda
Tremarctos
Bears
Pandas, Giant
Black Bears
Ursidae

The family of carnivorous or omnivorous bears, having massive bodies, coarse heavy fur, relatively short limbs, and almost rudimentary tails.


alpha-L-Fucosidase Deficiency
Fucosidase Deficiency
Fucosidase Deficiency Disease
Deficiency Disease, alpha-Fucosidase
Fucosidosis
Fucosidosis, Infantile
Fucosidosis Type I
Fucosidosis, Juvenile
Fucosidosis Type II
alpha-L-Fucosidase Deficiency Disease
Alpha-Fucosidase Deficiency
alpha-Fucosidase Deficiency Disease
Deficiency Disease, alpha-L-Fucosidase
Fucosidosis Type 1

An autosomal recessive lysosomal storage disease caused by a deficiency of ALPHA-L-FUCOSIDASE activity resulting in an accumulation of fucose containing SPHINGOLIPIDS; GLYCOPROTEINS, and mucopolysaccharides (GLYCOSAMINOGLYCANS) in lysosomes. The infantile form (type I) features psychomotor deterioration, MUSCLE SPASTICITY, coarse facial features, growth retardation, skeletal abnormalities, visceromegaly, SEIZURES, recurrent infections, and MACROGLOSSIA, with death occurring in the first decade of life. Juvenile fucosidosis (type II) is the more common variant and features a slowly progressive decline in neurologic function and angiokeratoma corporis diffusum. Type II survival may be through the fourth decade of life. (From Menkes, Textbook of Child Neurology, 5th ed, p87; Am J Med Genet 1991 Jan;38(1):111-31)


Gramicidin K
Gramoderm
Gramicidin B
Gramicidin J
Linear Gramicidin
Gramicidin A(1)
Gramicidin P
Gramicidin
Gramicidin Dubos
Gramicidin S
Gramicidin D
Gramicidin A
Gramicidin C
Gramicidins
Gramicidin NF

A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTHRICIN.


Nutritional Genomics
Nutrigenetics
Nutritional Genetics
Nutrigenomics

The study of the relationship between NUTRITIONAL PHYSIOLOGY and genetic makeup. It includes the effect of different food components on GENE EXPRESSION and how variations in GENES effect responses to food components.


Polylactic Acid-Polyglycolic Acid Copolymer

A co-polymer that consists of varying ratios of polylactic acid and polyglycolic acid. It is used as a matrix for drug delivery and for BONE REGENERATION.


Size, Bed
Bed Sizes, Hospital
Capacities, Hospital Bed
Bed Capacity, Hospital
Size, Hospital Bed
Bed Capacities, Hospital
Bed Size
Bed Size, Hospital
Capacity, Hospital Bed
Sizes, Bed
Bed Sizes
Hospital Bed Size
Sizes, Hospital Bed
Hospital Bed Capacity
Hospital Bed Sizes

The number of beds which a hospital has been designed and constructed to contain. It may also refer to the number of beds set up and staffed for use.


Apocillin
Pen VK
Phenoxymethylpenicillin
Beromycin
Beromycin, Penicillin
Penicillin V Potassium
Penicillin VK
Betapen
Penicillin V
Vegacillin
Penicillin, Phenoxymethyl
Penicillin V Sodium
Berromycin, Penicillin
V-Cillin K
Fenoxymethylpenicillin

A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.


A guanine-derived ANTINEOPLASTIC AGENT that functions as a NUCLEIC ACID SYNTHESIS INHIBITOR through its binding to, and inhibition of, THYMIDYLATE SYNTHASE.


Biological Products
Biologic Medicines
Biologic Drugs
Biologics
Biological Medicines
Biologic Pharmaceuticals
Natural Products
Biopharmaceuticals
Biologic Products
Biologicals
Products, Biological
Biological Drugs

Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay.


Fine Needle Biopsy
Aspiration Biopsy, Fine-Needle
Fine-Needle Aspiration
Biopsy, Fine-Needle

Using fine needles (finer than 22-gauge) to remove tissue or fluid specimens from the living body for examination in the pathology laboratory and for disease diagnosis.


Neoplasms, Urethral
Urethra Cancer
Urethral Neoplasms
Cancer of Urethra
Urethra Neoplasms
Cancer of the Urethra
Urethral Cancer

Cancer or tumors of the URETHRA. Benign epithelial tumors of the urethra usually consist of squamous and transitional cells. Primary urethral carcinomas are rare and typically of squamous cells. Urethral carcinoma is the only urological malignancy that is more common in females than in males.


Lectin Receptors
Mitogen Receptors
Receptors, Lectin
Mitogen Receptor
Receptors, Mitogen

Glycoprotein molecules on the surface of B- and T-lymphocytes, that react with molecules of antilymphocyte sera, lectins, and other agents which induce blast transformation of lymphocytes.


Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt

(1-hydroxyethylene)diphosphonic acid, Tetrapotassium Salt

A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.


Rousettus bat coronavirus HKU9
HCoV-HKU1
Tylonycteris bat coronavirus HKU4
Betacoronavirus
Human coronavirus HKU1
Pipistrellus bat coronavirus HKU5

A genus of the family CORONAVIRIDAE which causes respiratory or gastrointestinal disease in a variety of mostly mammals. Human betacoronaviruses include HUMAN ENTERIC CORONAVIRUS; HUMAN CORONAVIRUS OC43; MERS VIRUS; and SARS VIRUS. Members have either core transcription regulatory sequences of 5’-CUAAAC-3’ or 5’-CUAAAC-3’ and mostly have no ORF downstream to the N protein gene.


Azetidine-3-carboxylic Acid
Azetidine-2-carboxylic Acid
Azetidinecarboxylic Acid
3-azetidinecarboxylic Acid

A proline analog that acts as a stoichiometric replacement of proline. It causes the production of abnormal proteins with impaired biological activity.


Polycyclic Hydrocarbons
Cyclic Hydrocarbons
Hydrocarbons, Polycyclic
Hydrocarbons, Cyclic

Hydrocarbons consisting of two or more ring structures.


Generalized Resistance to Thyroid Hormone

An inherited autosomal recessive trait, characterized by peripheral resistance to THYROID HORMONES and the resulting elevation in serum levels of THYROXINE and TRIIODOTHYRONINE. This syndrome is caused by mutations of gene THRB encoding the THYROID HORMONE RECEPTORS BETA in target cells. HYPOTHYROIDISM in these patients is partly overcome by the increased thyroid hormone levels.


Infertility
Sterility, Reproductive
Reproductive Sterility
Sterility
Subfertility
Sub-Fertility

Complete inability to conceive or induce conception.


Synovial Osteochondromatosis
Reichel's Syndrome
Henderson-Jones Syndrome
Chondromatosis, Synovial
Synovial Chondrometaplasia
Synovial Chondromatosis
Osteochondromatosis, Synovial

Rare, benign, chronic, progressive metaplasia in which cartilage is formed in the synovial membranes of joints, tendon sheaths, or bursae. Some of the metaplastic foci can become detached producing loose bodies. When the loose bodies undergo secondary calcification, the condition is called synovial osteochondromatosis.


Achromycin V
Tetracycline
4-Epitetracycline
Topicycline
Tetracycline Hydrochloride
Tetracycline Monohydrochloride
Sustamycin
Achromycin
Hostacyclin
Tetrabid

A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.


Candida parapsilosis Group
C. parapsilosis Complex
Candida parapsilosis
Candida metapsilosis
C. orthopsilosis
C. parapsilosis
Candida parapsilosis Complex
C. metapsilosis
Candida orthopsilosis

A species of MITOSPORIC FUNGI and opportunistic pathogen associated with its ability to form BIOFILMS in catheters and parenteral nutrition IV lines. C. parapsilosis complex includes closely related species C. orthopsilosis; and C. metapsilosis.


Acanthamoeba polyphaga mimivirus
Mimiviridae
Mimivirus

A virus whose host is the amoeba Acanthamoeba polyphaga. Mimivirus is a putative pathogen of human PNEUMONIA.


Cyclic peptide that acts as a platelet glycoprotein IIB-IIIA antagonist, reversibly inhibiting the binding of FIBRINOGEN; VON WILLEBRAND FACTOR; and other adhesive molecules to the GPIIB-IIIA RECEPTORS of platelets. It is used in the management of UNSTABLE ANGINA and in patients undergoing coronary ANGIOPLASTY and stenting procedures.


Serotonin 5-HT1D Receptor Antagonists
Serotonin 5-HT1 Receptor Antagonists
5-HT1B Antagonist
Serotonin 5-HT1A Receptor Antagonists
Serotonin 5-HT1B-D Antagonists
Serotonin 5-HT1B Receptor Antagonists
5-HT1 Antagonist
5-HT1A Antagonist
5-HT1 Antagonists
5-HT1D Antagonist
5-HT1B-D Antagonist

Drugs that bind to but do not activate SEROTONIN 5-HT1 RECEPTORS, thereby blocking the actions of SEROTONIN 5-HT1 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more of the specific 5-HT1 receptor subtypes.


Models, Proportional Hazards
Hazard Models
Cox Proportional Hazards Models
Cox Models
Proportional Hazards Models
Proportional Hazard Models
Hazards Models

Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.


Puncto E
Dal-E
Bio E
Tocopherols
Biosan
E Vitamin E
Evion
Bioweyxin
Richtavit E
Biopto-E
Vitamin-E EVI-MIRALE
Eplonat
EUNOVA Vitamin E
Auxina E
Spondyvit
Equivit E
Vitamin E Natur
E-ferol
Vita-Plus E
Unique E
Vitamin-E Dragees
Micorvit E
Vitamin E Sanum
Uno-Vit
Detulin
Aquasol E
Tocopharm
Dermorelle
Embial
Lasar
Vitamin E AL
E-Vicotrat
Davitamon
Ephynal
Malton E
Togasan Vitamin E
Vit E hydrosol
Vibolex
Tocovital
Vitagutt Vitamin E
Eusovit
Vit. E Stada
Abortosan
Tocopherol
Tocopherol Bayer
E-Mulsin
Snow-E Muscle, Energy & Feritility
Vita-E
Ecoro
Tocopa
Vitamin E Suspension
Vitazell
Antioxidans E-Hevert
Tocolion
Sanavitan S
Hydrovit E
Vitamin E-mp
E-Vitamin-Ratiopharm
Vitamine E GNR
Mowivit Vitamin E
Elex Verla

A collective name for a group of closely related lipids that contain substitutions on the 2H-1-benzopyran-6-ol nucleus and a long hydrocarbon chain of isoprenoid units. They are antioxidants by virtue of the phenolic hydrogen. Tocopherols react with the most reactive form of oxygen and protect unsaturated fatty acids from oxidation.


Intal
Cromolyn
Bicromat Spray
Nasalcrom
FPL-670
Aarane
Vicrom
Cromolyn Sodium
Sodium Cromoglycate
Opticrom
Cromoglycic Acid
Cromoglicic Acid
Disodium Cromoglycate
Nalcrom
Cromoglycate
Lomudal

A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.


Poisoning, Blood
Blood Poisoning
Sepsis
Severe Sepsis
Septicemia
Pyaemia
Pyemia
Pyohemia

Systemic disease associated with the presence of pathogenic microorganisms or their toxins in the blood.


Malayi Filariasis
Lymphatic Filariasis
Elephantiasis, Filarial
Bancroftian Filariasis
Bancroftian Elephantiasis
Filariasis, Lymphatic
Elephantiasis, Malayi
Filarial Elephantiasis
Elephantiasis, Bancroftian

Parasitic infestation of the human lymphatic system by WUCHERERIA BANCROFTI or BRUGIA MALAYI. It is also called lymphatic filariasis.


Neoplasms, Cervix
Uterine Cervical Cancer
Uterine Cervical Neoplasms
Cancer of the Cervix
Cancer of the Uterine Cervix
Cervix Cancer
Cervix Neoplasms
Cervical Neoplasms
Neoplasms, Cervical
Cervical Cancer
Cancer of Cervix


Prenatal Structures
Embryo
Embryonic Structures
Embryos

The entities of developing ANIMALS in early stages.


A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.


Senile Dementia, Alzheimer Type
Familial Alzheimer Disease (FAD)
Late Onset Alzheimer Disease
Dementia, Primary Senile Degenerative
Alzheimer Dementia
Alzheimer Disease
Focal Onset Alzheimer's Disease
Alzheimer's Disease, Focal Onset
Alzheimer Disease, Late Onset
Acute Confusional Senile Dementia
Primary Senile Degenerative Dementia
Alzheimer Sclerosis
Dementia, Alzheimer Type
Alzheimer-Type Dementia (ATD)
Alzheimer's Disease
Early Onset Alzheimer Disease
Dementia, Presenile
Senile Dementia, Acute Confusional
Alzheimer Syndrome
Presenile Alzheimer Dementia
Alzheimer Disease, Early Onset
Dementia, Senile
Alzheimer Type Senile Dementia

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)


Levocarnitine
L-Carnitine
Bicarnesine
Vitamin BT
Carnitine

A constituent of STRIATED MUSCLE and LIVER. It is an amino acid derivative and an essential cofactor for fatty acid metabolism.


Expressed in Non-Metastatic Cells 2 Protein

Tumor Metastatic Process-Associated Protein

A family of nucleotide diphosphate kinases that play a role in a variety of cellular signaling pathways that effect CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS. They are considered multifunctional proteins that interact with a variety of cellular proteins and have functions that are unrelated to their enzyme activity.


Arthroscopic Subchondral Bone Microfracture

Surgical techniques used to correct or augment healing of chondral defects in the joints (CARTILAGE, ARTICULAR). These include abrasion, drilling, and microfracture of the subchondral bone to enhance chondral resurfacing via autografts, allografts, or cell transplantation.


Family Research
Stepfamily
Family Members
Relatives
Extended Family
Filiation
Family Life Cycle
Family
Kinship Networks
Family, Reconstituted
Family Life Cycles

A social group consisting of parents or parent substitutes and children.


Conflict Resolution
Arbitrating
Negotiation
Arbitration
Negotiating
Mediation
Mediating

The process of bargaining in order to arrive at an agreement or compromise on a matter of importance to the parties involved. It also applies to the hearing and determination of a case by a third party chosen by the parties in controversy, as well as the interposing of a third party to reconcile the parties in controversy.


Desoxi Topisolon Desoximetasone Topicort Topicorte 17-Desoxymethasone Flubason A-41304 Stiedex Desoxymethasone Deoxydexamethasone Ibaril

A topical anti-inflammatory glucocorticoid used in DERMATOSES, skin allergies, PSORIASIS, etc.


Cress, Upland
Rocket, Yellow
Yellow Rocket
Barbarea verna
Cress, Winter
Barbarea
Barbarea vulgaris


Puberty, Precocious
Familial Precocious Puberty
Sexual Precocity
Testotoxicosis
Precocious Puberty
Precocious Puberty, Male-Limited
Precocious Puberty, Central
Pubertas Praecox
Idiopathic Sexual Precocity
Precocious Puberty, Male Limited

Familial precocious puberty in boys usually presents by age 4 with rapid VIRILIZATION and is also characterized by gonadotropin-independent testosterone secretion, low secretion of LUTEINIZING HORMONE, and advanced SPERMATOGENESIS in the testis. Mutations in the LHCGR gene have been identified. OMIM: 176410


Habenular Commissure
Habenula
Habenular Nuclei
Habenular Nucleus
Habenula Complex
Commissura Habenularum
Nucleus Habenularis

A small protuberance at the dorsal, posterior corner of the wall of the THIRD VENTRICLE, adjacent to the dorsal THALAMUS and PINEAL BODY. It contains the habenular nuclei and is a major part of the epithalamus.


Chondroitin Sulfate 4-Sulfate, Sodium Salt

Derivatives of chondroitin which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. Chondroitin sulfate A, or chondroitin 4-sulfate, and chondroitin sulfate C, or chondroitin 6-sulfate, have the sulfate esterified in the 4- and 6-positions, respectively. Chondroitin sulfate B (beta heparin; DERMATAN SULFATE) is a misnomer and this compound is not a true chondroitin sulfate.


A plant species of the family POACEAE that is widely cultivated for its EDIBLE GRAIN.


Thymopoietin I
Thymopoietins
Thymopoietin II
Thymins
TP-49

Two closely related polypeptides (molecular weight 7,000) isolated from the thymus gland. These hormones induce the differentiation of prothymocytes to thymocytes within the thymus. They also cause a delayed impairment of neuromuscular transmission in vivo and are therefore believed to be the agent responsible for myasthenia gravis.


Genetic Databases
Databases, Genetic
Genetic Data Bases
Genetic Sequence Databases
Online Mendelian Inheritance In Man
OMIM
Genetic Information Databases
Genetic Databanks
Genetic Data Banks

Databases devoted to knowledge about specific genes and gene products.


Larvae Maggots Maggot Tadpoles Larva Tadpole

Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.


Motor Neuron Disease
Motor Neuron Disease, Familial
Motor Neuron Disease, Secondary
Secondary Motor Neuron Disease
Motor Neuron Disease, Lower
Lower Motor Neuron Disease
Motor Neuron Disease, Upper
Anterior Horn Cell Disease
Primary Lateral Sclerosis
Familial Motor Neuron Disease
Motor System Disease
Upper Motor Neuron Disease
Lateral Sclerosis

Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)


Bos indicus
Cattle
Bos taurus
Yak
Cow, Domestic
Zebu
Bos grunniens

Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.


Atherosclerotic Disease, Carotid
Arterial Diseases, Common Carotid
Carotid Atherosclerosis
Carotid Artery Disorders
Arterial Diseases, Carotid
Common Carotid Artery Diseases
Arterial Diseases, External Carotid
Carotid Atherosclerotic Disease
Carotid Artery Diseases
Arterial Diseases, Internal Carotid
External Carotid Artery Diseases
Internal Carotid Artery Diseases

Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.


Chronic Obstructive Pulmonary Disease
COPD
Chronic Obstructive Lung Disease
Chronic Obstructive Airway Disease
COAD
Chronic Airflow Obstruction
Pulmonary Disease, Chronic Obstructive
Airflow Obstruction, Chronic

A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.


Viral Core Proteins
Influenza Virus Core Proteins
Adenovirus Core Protein VII
Virus Core Proteins
Major Core Protein lambda-1
Oncornaviral Protein P19
Core Protein lambda 2
Major Core Protein sigma-2
P30 Core Proteins
Core Proteins, Viral
Major Core Protein
Major Core Protein lambda 1
Major Core Proteins, Viral
Viral Protein P19
Major Core Protein sigma 2
Core Protein V
OVP 19

Proteins found mainly in icosahedral DNA and RNA viruses. They consist of proteins directly associated with the nucleic acid inside the NUCLEOCAPSID.


Coronary Angioplasty, Transluminal Balloon

Percutaneous Transluminal Coronary Angioplasty

Angioplasty, Transluminal, Percutaneous Coronary

Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.


Baculoviral IAP Repeat-Containing 2 Protein

Baculoviral Inhibitor Of Apoptosis Repeat Proteins

Baculoviral IAP Repeat Containing Protein 2

Cellular Inhibitor of Apoptosis 1 Protein

A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.


Calovo virus
Bunyamwera Group Viruses
Cache Valley virus
Bunyamwera virus
Batai virus
Chittoor virus

A species in the ORTHOBUNYAVIRUS genus of the family BUNYAVIRIDAE. A large number of serotypes or strains exist in many parts of the world. They are transmitted by mosquitoes and infect humans in some areas.


Male Fern
Aspidium filix-mas
Dryopteris
Fern, Male
Dryopteris filix-mas

A plant genus of the family DRYOPTERIDACEAE. Members contain aspidin and filicic acid.


Hamsters, Syrian
Hamsters, Golden
Hamsters, Golden Syrian
Mesocricetus auratus
Mesocricetus

A genus of the family Muridae having three species. The present domesticated strains were developed from individuals brought from Syria. They are widely used in biomedical research.


Carphecillin
Carfecillin Sodium Salt
Carbenicillin Phenyl Sodium
BRL-3475
Carfecillin
Uticillin

The phenyl ester of CARBENICILLIN that, upon oral administration, is broken down in the intestinal mucosa to the active antibacterial. It is used for urinary tract infections.


Natriuretic Hormones
Natriuretic Effects
Natriuretic Agents
Chloriuretic Hormones
Natriuretic Factors
Natriuretic Effect

Endogenous chemicals that regulate the WATER-ELECTROLYTE BALANCE in the body, such as the NATRIURETIC PEPTIDES.


Acetonemia
Ketoaciduria
Ketoacidosis
Ketonemia
Ketonuria
Metabolic Ketosis
Acetonuria
Ketosis
Metabolic Ketoacidosis
Ketoacidemia

A condition characterized by an abnormally elevated concentration of KETONE BODIES in the blood (acetonemia) or urine (acetonuria). It is a sign of DIABETES COMPLICATION, starvation, alcoholism or a mitochondrial metabolic disturbance (e.g., MAPLE SYRUP URINE DISEASE).


Records Management
Forms Control
Records Control
Forms and Records Control

A management function in which standards and guidelines are developed for the development, maintenance, and handling of forms and records.


Smoking Blunts
Marijuana Smoking
Smoking, Blunts
Cannabis Smoking
Hashish Smoking
Marihuana Smoking

Smoking of hollowed out cigars or cigarettes filled with MARIJUANA.


Dystroglycan
alpha-Dystroglycan
Dystroglycan 1
Dystroglycans
Cranin
beta-Dystroglycan
Dystrophin-Associated Glycoprotein 1

Dystrophin-associated proteins that play role in the formation of a transmembrane link between laminin-2 and DYSTROPHIN. Both the alpha and the beta subtypes of dystroglycan originate via POST-TRANSLATIONAL PROTEIN PROCESSING of a single precursor protein.


Neuronal Ceroid Lipofuscinosis, Infantile

Ceroid Lipofuscinosis, Neuronal, Parry Type

Kufs Type Neuronal Ceroid Lipofuscinosis

Late-Infantile Neuronal Ceroid Lipofuscinosis

Neuronal Ceroid Lipofuscinosis, Late Infantile

Neuronal Ceroid Lipofuscinosis, Juvenile

Ceroid Lipofuscinosis, Neuronal 3, Juvenile

Ceroid Lipofuscinosis, Neuronal, 4A, Autosomal Recessive

Ceroid Lipofuscinosis, Neuronal, 4B, Autosomal Dominant

Neuronal Ceroid Lipofuscinosis, Adult Type

Neuronal Ceroid Lipofuscinosis, Late-Infantile

Neuronal Ceroid Lipofuscinosis Juvenile Type

This type is caused by mutation in the gene (CLN1or PPT1) encoding palmitoyl-protein thioesterase (THIOLESTER HYDROLASES), an enzyme involved in catabolism of lipid-modified proteins.


Bioelectrical Impedance
Ohmic Resistance
Biolectric Impedance
Electrical Impedance
Impedance
Electric Impedance
Electric Resistance
Electrical Resistance

The resistance to the flow of either alternating or direct electrical current.


CNP-22
C-Type Natriuretic Peptide
CNP-53
Natriuretic Peptide, C-Type
C-Type Natriuretic Peptide-53
C-Type Natriuretic Peptide-22

A PEPTIDE of 22 amino acids, derived mainly from cells of VASCULAR ENDOTHELIUM. It is also found in the BRAIN, major endocrine glands, and other tissues. It shares structural homology with ATRIAL NATRIURETIC FACTOR. It has vasorelaxant activity thus is important in the regulation of vascular tone and blood flow. Several high molecular weight forms containing the 22 amino acids have been identified.


Streptococcus Group A
Bacteria, Flesh-Eating
Streptococcus pyogenes
Flesh-Eating Bacteria

A species of gram-positive, coccoid bacteria isolated from skin lesions, blood, inflammatory exudates, and the upper respiratory tract of humans. It is a group A hemolytic Streptococcus that can cause SCARLET FEVER and RHEUMATIC FEVER.


Movies
Films as Topic
Motion Pictures
Cinema
Movies as Topic
Films

A theater where people can view MOTION PICTURES.


Psychotherapists
Clinical Psychotherapists
Schema Therapy
Psychotherapy
Logotherapy

Therapy that emphasizes lifelong patterns, affective change techniques, and the therapeutic relationship. (https://www.apa.org/pubs/videos/4310804)


Dihydroxyundecyl Resorcylic Acid Lactone


Gastrointestinal Microbial Community
Enteric Bacteria
Gut Flora
Intestinal Flora
Intestinal Microbiota
Gastrointestinal Flora
Gut Microbiome
Gastrointestinal Microbiome
Gastric Microbiome
Intestinal Microbiome
Gut Microflora
Gut Microbiota
Gastrointestinal Microbiota
Intestinal Microflora
Gastrointestinal Microflora

All of the microbial organisms that naturally exist within the GASTROINTESTINAL TRACT.


Autonomic Agents
Autonomic Effect
Autonomic Effects
Autonomic Drugs

Agents affecting the function of, or mimicking the actions of, the autonomic nervous system and thereby having an effect on such processes as respiration, circulation, digestion, body temperature regulation, certain endocrine gland secretions, etc.


Hyalinosis, Segmental
Hyalinosis, Segmental Glomerular
Segmental Glomerular Hyalinosis
Glomerulosclerosis, Focal Segmental
Focal Segmental Glomerulosclerosis
Glomerulosclerosis, Focal
Glomerulonephritis, Focal Sclerosing

Segmental glomerular degeneration with a glassy appearance (hyalinosis) caused by the accumulation of plasma proteins in the glomeruli.


Brain Hypoxia
Encephalopathy, Hypoxic
Brain Anoxia
Hypoxia, Cerebral
Hypoxic Encephalopathy
Anoxia, Cerebral
Anoxic Encephalopathy
Hypoxia, Brain
Anoxic Brain Damage
Hypoxic Brain Damage
Cerebral Anoxia
Anoxia, Brain
Cerebral Hypoxia

A reduction in brain oxygen supply due to ANOXEMIA (a reduced amount of oxygen being carried in the blood by HEMOGLOBIN), or to a restriction of the blood supply to the brain, or both. Severe hypoxia is referred to as anoxia, and is a relatively common cause of injury to the central nervous system. Prolonged brain anoxia may lead to BRAIN DEATH or a PERSISTENT VEGETATIVE STATE. Histologically, this condition is characterized by neuronal loss which is most prominent in the HIPPOCAMPUS; GLOBUS PALLIDUS; CEREBELLUM; and inferior olives.


Congenital Insensitivity to Pain with Anhidrosis

Hereditary Sensory Autonomic Neuropathy, Type 5

Neuropathy, Hereditary Sensory And Autonomic, Type I

Sensory and Autonomic Neuropathies, Hereditary

Neuropathy Hereditary Sensory and Autonomic Type 1

Neuropathy, Hereditary Sensory Radicular, Autosomal Dominant

Hereditary Sensory Autonomic Neuropathy, Type 1

Hereditary Sensory and Autonomic Neuropathy Type 1

Insensitivity to Pain with Anhidrosis, Congenital

Neuropathies, Hereditary Sensory and Autonomic

Hereditary Sensory and Autonomic Neuropathies

Hereditary Sensory and Autonomic Neuropathy 4

Insensitivity to Pain, Congenital, with Anhidrosis

Hereditary Sensory Radicular Neuropathy, Recessive Form

Neuropathy, Progressive Sensory, Of Children

Hereditary Sensory and Autonomic Neuropathy, Type 4

Neuropathy, Hereditary Sensory And Autonomic, Type V

Pain Insensitivity with Anhidrosis, Congenital

Hereditary Sensory and Autonomic Neuropathy, Type 5

Hereditary Sensory and Autonomic Neuropathy Type V

Hereditary Sensory And Autonomic Neuropathy IV

Hereditary Sensory and Autonomic Neuropathy Type IV

Hereditary Sensory and Autonomic Neuropathy Type 2

Neuropathy, Hereditary Sensory Radicular, Autosomal Recessive

Hereditary Sensory Autonomic Neuropathy, Type 4

HSAN (Hereditary Sensory Autonomic Neuropathy)

Hereditary Sensory and Autonomic Neuropathy Type II

Neuropathy Hereditary Sensory Radicular, Autosomal Dominant

Neuropathy, Congenital Sensory, with Anhidrosis

Hereditary Sensory Autonomic Neuropathy, Type 2

A group of inherited disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and clinically by loss of sensation and autonomic dysfunction. There are five subtypes. Type I features autosomal dominant inheritance and distal sensory involvement. Type II is characterized by autosomal inheritance and distal and proximal sensory loss. Type III is DYSAUTONOMIA, FAMILIAL. Type IV features insensitivity to pain, heat intolerance, and mental deficiency. Type V is characterized by a selective loss of pain with intact light touch and vibratory sensation. (From Joynt, Clinical Neurology, 1995, Ch51, pp142-4)


NAD(P) Nucleosidase
NAD-Glycohydrolases
NAD+ Nucleosidase
NADP-Glycohydrolase
NAD+ Nucleosidases
DPNase
NAD-Glycohydrolase
NADases
NADase
NADP Nucleosidase
Diphosphopyridine Nucleotidases
Ecto-NAD+ Glycohydrolase
Diphosphopyridine Nucleotidase
NAD+ Glycohydrolase

An enzyme that catalyzes the hydrolysis of nicotinamide adenine dinucleotide (NAD) to NICOTINAMIDE and ADENOSINE DIPHOSPHATE RIBOSE. Some are extracellular (ectoenzymes).The enzyme from some sources also catalyses the hydrolysis of nicotinamide adenine dinucleotide phosphate (NADP).


Acute Myeloid Leukemia without Maturation

Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.


Quillaja Saponaria
Soapbush
Quillaja
Soapbark

A plant genus of the family ROSACEAE whose members produce SAPONINS.


CBF Protein, CCAAT-Binding
CCAAT-Binding Transcription Factor
CBF-A Protein, CCAAT-Binding
CBF-C Protein, CCAAT-Binding
CCAAT-Binding Protein, CP1
CCAAT-Binding Factor
CCAAT-Binding Factor, B-Subunit
CCAAT-Binding-Factor
CCAAT-Binding Factor, C-Subunit
CCAAT-Binding Factor, A-Subunit
NF-Y Protein
CBF-B Protein, CCAAT-Binding

A heterotrimeric DNA-binding protein that binds to CCAAT motifs in the promoters of eukaryotic genes. It is composed of three subunits: A, B and C.


An indole and pyrrole derivative that inhibits VEGFR-2 and PDGFR BETA RECEPTOR TYROSINE KINASES. It is used as an antineoplastic agent for the treatment of GASTROINTESTINAL STROMAL TUMORS, and for treatment of advanced or metastatic RENAL CELL CARCINOMA.


Anabolic Steroids
Testosterone Congeners
Synthetic Androgens
Androgen Analogs
Androgen Analogues
Androgens, Synthetic

Steroidal compounds related to TESTOSTERONE, the major mammalian male sex hormone. Testosterone congeners include important testosterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with androgenic activities.


Burningbush (Euonymus)
Euonymus sieboldianus
Euonymus
Spindletree

A plant genus of the family CELASTRACEAE.


GTP-Binding Protein alpha Subunits, Gq-G11

A family of heterotrimeric GTP-binding protein alpha subunits that activate TYPE C PHOSPHOLIPASES dependent signaling pathways. The Gq-G11 part of the name is also spelled Gq/G11.


An anti-cholesteremic agent that inhibits delta 7-reductase, delta 14 reductase, and sterol biosynthesis.


Minute projections of cell membranes which greatly increase the surface area of the cell.


Systemic Enzyme Therapy
Enzyme Therapy
Enzymotherapy


Glatiramer Acetate
Copaxone
TV 5010
Glatiramer
TV-5010
TV5010

A random polymer of L-ALANINE, L-GLUTAMIC ACID, L-LYSINE, and L-TYROSINE that structurally resembles MYELIN BASIC PROTEIN. It is used in the treatment of RELAPSING-REMITTING MULTIPLE SCLEROSIS.


Pyelonephritis
Pyelonephritis, Acute Necrotizing
Necrotizing Pyelonephritis

Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.


Fern, Rainbow
Selaginellaceae
Moss, Spike
Spikemoss
Selaginella

A plant family of the order Selaginellales, class Lycopodiopsida, division Lycopodiophyta, subkingdom TRACHEOPHYTA. Members contain bilobetin. The rarely used common name of resurrection plant is mainly used with CRATEROSTIGMA.


Pharmacogenomic Study
Pharmacogenomic Testing
Pharmacogenetic Testing
Pharmacogenetic Analysis
Pharmacogenetic Screening
Pharmacogenetic Study
Pharmacogenomic Analysis
Pharmacogenomic Screening

The detection of genetic variability (e.g., PHARMACOGENOMIC VARIANTS) relevant to PHARMACOGENETICS and PRECISION MEDICINE. The purpose of such genetic testing is to help determine the most effective treatment options and their optimum dosages with least potential risks for DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS.


Liquid Crystalline Materials
Liquid Crystals
Mesomorphous Phase Materials

Materials in intermediate state between solid and liquid.


SOX-11 Transcription Factor
SOX-4 Transcription Factor
SOX4 Transcription Factor
SOX12 Transcription Factor
Group C SOX Transcription Factors
SOX-12 Transcription Factor
SOX11 Transcription Factor
SOXC Transcription Factors

A subclass of closely-related SOX transcription factors. Members of the group have been found expressed in developing neuronal tissue, LYMPHOCYTES, and during EMBRYONIC DEVELOPMENT.


Early Promoters, Genetic
Promotor, Genetic
Pseudopromoter, Genetic
Promotor Regions
Middle Promoters, Genetic
Promoter Regions, Genetic
Late Promoters, Genetic
Promoter, Genetic
Promoter Regions
rRNA Promoter

DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.


Chlormequat Chloride
Chlormequat
Cycocel
Chlorocholine Chloride
Chlorinecolinchloride

A plant growth regulator that is commonly used on ornamental plants.


Nephrox
Amphojel
Pepsamer
Alhydrogel
Dialume
Alugel
Basalgel
Brasivil
Hydrated Alumina
Rocgel
Aluminum Hydroxide
Algeldrate
Aldrox

A compound with many biomedical applications: as a gastric antacid, an antiperspirant, in dentifrices, as an emulsifier, as an adjuvant in bacterins and vaccines, in water purification, etc.


An ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER that is used to manage HYPERTENSION.


Pneumocystis carinii
Pneumocystis jirovecii
Pneumocystis carini
Pneumocystis jiroveci

The prototype species of PNEUMOCYSTIS infecting the laboratory rat. It was formerly called Pneumocystis carinii f. sp. carinii. Strains that infect humans and cause PNEUMOCYSTIS PNEUMONIA were originally classified as Pneumocystis jirovecii or Pneumocystis carinii f. sp. hominis.


Three-Dimensional Imaging, Computer Generated

Imaging, Three-Dimensional, Computer Assisted

The generation of three dimensional images with the aid of computers.


A serotonin antagonist with limited antihistaminic, anticholinergic, and immunosuppressive activity.


Weight-Loss Agents
Antiobesity Agents
Anti-Obesity Drugs
Weight-Loss Drugs
Anti-Obesity Agents
Antiobesity Drugs

Agents that increase energy expenditure and weight loss by neural and metabolic regulation.


Mean Corpuscular Hemoglobulin Concentration

A measure of the variability in size of circulating ERYTHROCYTES. It is expressed as the coefficient of variation of the erythrocyte volume.


Ametop
Tetrakain
Dicaine
Pontocaine
Pantocaine
Tetracaine Monohydrochloride
Tetracaine
Tetrracaine Hydrochloride
Amethocaine

A potent local anesthetic of the ester type used for surface and spinal anesthesia.


Falithrom Phenprocoumalol Phenylpropylhydroxycumarinum Marcumar Phenprocoumon Phenprogramma Phenprocoumarol Marcoumar Liquamar

Coumarin derivative that acts as a long acting oral anticoagulant.


Subacromial Impingement Syndrome
Internal Impingement Syndrome
Rotator Cuff Impingement
Coracoid Impingement Syndrome
Posterosuperior Glenoid Impingement
Outlet Impingement
Shoulder Impingement Syndrome
Coracohumeral Impingement Syndrome
Rotator Cuff Impingement Syndrome
Outlet Impingement Syndrome
Shoulder Impingement
Coracohumeral Impingement

Compression of the ROTATOR CUFF tendons and subacromial bursa between the HUMERAL HEAD and  the ACROMION of the SCAPULA. This condition is associated with subacromial BURSITIS, as well as rotator cuff (largely supraspinatus) and bicipital tendon INFLAMMATION.


Parents
Stepparent
Parenthood Status
Parental Age
Step-Parents

Persons functioning as natural, adoptive, or substitute parents. The heading includes the concept of parenthood as well as preparation for becoming a parent.


Matricaria chamomilla
Mayweed, Crown
Camomile, German
Chamomile, German
Pineapple Weed
Chamomilla recutita
Matricaria recutita
Matricaria
Matricaria matricarioides
German Chamomile

A plant genus of the family ASTERACEAE. M. chamomilla appears similar to Anthemis but this flower disk is conical and hollow and lacks chaffy bract scales and the odor is weaker. The common name of 'manzanilla' is confused with other meanings of the word. 'Matricaria chamomilla sensu' is classified by some as Tripleurospermum perforata. Other plants with similar common names include CHAMAEMELUM; TRIPLEUROSPERMUM and ANTHEMIS.


Metrazol Pentylenetetrazol Pentamethylenetetrazole Pentylenetetrazole Korazol Korazole Metrazole Pentazol Pentetrazole Cardiazol Corasol Corazole Corazol Leptazole

A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.


Rhoxal-Nitrazepam
Radedorm
Nitrazepam-Neuraxpharm
Eatan
Imadorm
Nitrazep
Nitrodiazepam
Dormo-Puren
Mogadon
Dormalon
Alodorm
Serenade
Nitrazepam
Imeson
Nitrazadon
Somnite
Remnos
Novanox
Nitrazepam AL

A benzodiazepine derivative used as an anticonvulsant and hypnotic.


IRS Signaling Adaptor Proteins
Insulin Receptor Substrate-3
Insulin Receptor Substrate-1 Protein
Insulin Receptor Substrate Proteins
Insulin Receptor Substrate-3 Protein
Insulin Receptor Substrate-4
Insulin Receptor Substrate-2
Insulin Receptor Substrate-4 Protein
Insulin Receptor Substrate-1
Insulin Receptor Substrate-2 Protein

A structurally-related group of signaling proteins that are phosphorylated by the INSULIN RECEPTOR PROTEIN-TYROSINE KINASE. The proteins share an N-terminal PLECKSTRIN HOMOLOGY DOMAIN, a phosphotyrosine-binding domain that interacts with the phosphorylated INSULIN RECEPTOR, and a C-terminal TYROSINE-rich domain. Upon tyrosine phosphorylation, insulin receptor substrate proteins interact with specific SH2 DOMAIN containing proteins that are involved in insulin receptor signaling.


Nervous System Physiological Concepts
Nervous System Physiological Process
Physiology, Nervous System
Nervous System Physiological Processes
Nervous System Physiology
Nervous System Physiological Phenomena
Nervous System Physiologic Processes
Nervous System Physiological Phenomenon

Biological actions and events that constitute the functions of the NERVOUS SYSTEM.


Short Rib-Polydactyly Syndrome, Majewski Type

Polydactyly with Neonatal Chondrodystrophy, Type 2

Polydactyly With Neonatal Chondrodystrophy, Type II

Polydactyly with Neonatal Chondrodystrophy, Type 1

Short Rib-Polydactyly Syndrome, Saldino-Noonan Type

A syndrome inherited as an autosomal recessive trait and incompatible with life. The main features are narrow thorax, short ribs, scapular and pelvic dysplasia, and polydactyly.


Hyper-Immunoglobulin E Syndrome, Autosomal Dominant

Hyper-Immunoglobulin E Syndrome, Autosomal Recessive

Hyper-IgE Recurrent Infection Syndrome, Autosomal Recessive

Hyperimmunoglobulin E, Recurrent Infection Syndrome

Hyperimmunoglobulin E-Recurrent Infection Syndrome

Primary immunodeficiency syndrome characterized by recurrent infections and hyperimmunoglobulinemia E. Most cases are sporadic. Of the rare familial forms, the dominantly inherited subtype has additional connective tissue, dental and skeletal involvement that the recessive type does not share.


Stimulus Deprivation-Induced Amblyopia
Lazy Eye
Amblyopia, Developmental
Amblyopia, Stimulus Deprivation-Induced
Amblyopia
Amblyopia, Suppression
Anisometropic Amblyopia

A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.


An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.


Sleep Disorder, Shift-Work
Sleep-Wake Disorder, Non-24 Hour
Advanced Sleep Phase Syndrome
Sleep Disorders, Circadian Rhythm
Disturbed Nyctohemeral Rhythm
Delayed Sleep-Phase Syndrome
Sleep-Wake Schedule Disorders
Circadian Rhythm Sleep Disorders
Shift-Work Sleep Disorder
Non-24 Hour Sleep-Wake Disorder
Nonorganic Sleep Wake Cycle Disorders
Sleep-Wake Cycle Disorders
Delayed Sleep Phase Syndrome

Dyssomnias associated with disruption of the normal 24 hour sleep wake cycle secondary to travel (e.g., JET LAG SYNDROME), shift work, or other causes.


Aneurysm, Dissecting
Dissection, Blood Vessel
Blood Vessel Dissection
Aortic Dissection
Dissecting Aneurysm

An aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the tunica intima and TUNICA MEDIA causes luminal occlusion. Dissection at the media, or between the media and the outer ADVENTITIA causes aneurismal dilation.


Rotenone-Sensitive Mitochondrial NADH-Ubiquinone Oxidoreductase

A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UBIQUINONE to ubiquinol. In MITOCHONDRIA the complex also couples its reaction to the transport of PROTONS across the internal mitochondrial membrane. The NADH DEHYDROGENASE component of the complex can be isolated and is listed as EC 1.6.99.3.


Miliary Aneurysm
Charcot-Bouchard Aneurysms
Microaneurysm
Charcot-Bouchard Aneurysm
Retinal Microaneurysm

Aneurysm of the MICROVASCULATURE. Charcot–Bouchard aneurysms are aneurysms of the brain vasculature which is a common cause of CEREBRAL HEMORRHAGE. Retinal microaneurysm is an early diagnostic sign of DIABETIC RETINOPATHY.


Achondroplasia, Severe, With Developmental Delay And Acanthosis Nigricans

Severe Achondroplasia with Developmental Delay and Acanthosis Nigricans

An autosomal dominant disorder that is the most frequent form of short-limb dwarfism. Affected individuals exhibit short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and mid-face hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, GENU VARUM, and trident hand. (Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim, MIM#100800, April 20, 2001)


21st Cent. History of Medicine
21st Cent. History (Medicine)
History of Medicine, 21st Cent.
Medicine, 21st Cent.
21st Cent. Medicine
History, Twenty-first Century
Medical History, 21st Cent.
21st Century History
History, 21st Century
Historical Events, 21st Century

Events and developments in medicine during the 100 year period following the 20th century.


Receptors, ATP
ATP Receptors
Receptors, Purinergic P2
ADP Receptor
P2 Purinoceptors
ADP Receptors
P2 Purinoceptor
Receptor, Purinergic P2
ATP Receptor
Purinergic P2 Receptors
Receptors, ADP

A class of cell surface receptors for PURINES that prefer ATP or ADP over ADENOSINE. P2 purinergic receptors are widespread in the periphery and in the central and peripheral nervous system.


Pigmentary Cirrhosis
Primary Hemochromatosis
Haemochromatosis
Hemochromatoses
Bronze Diabetes
Bronzed Cirrhosis
Diabetes, Bronze
Hemochromatosis
Von Recklenhausen-Applebaum Disease
Genetic Hemochromatosis
Iron Storage Disorder
Troisier-Hanot-Chauffard Syndrome
Familial Hemochromatosis

A disorder of iron metabolism characterized by a triad of HEMOSIDEROSIS; LIVER CIRRHOSIS; and DIABETES MELLITUS. It is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed)


Adipose-Derived Mesenchymal Stromal Cells

Adipose Tissue-Derived Mesenchymal Stem Cells

Adipose Tissue-Derived Mesenchymal Stromal Cells

Mesenchymal stromal cells found in WHARTON JELLY, in the perivascular, intervascular, and subamnion regions of the UMBILICAL CORD. They are fibroblastic in appearance, rich in hyaluronic acid, and have been induced to form bone, CARTILAGE, and adipose cells in vitro.


Bay-1040
Adalat
Procardia XL
Procardia
Vascard
BAY-a-1040
Nifedipine-GTIS
Nifedipine Monohydrochloride
Nifangin
Nifedipine
Cordipine
Fenigidin
Korinfar
Cordipin
Corinfar

A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.


Chemicals, Hazardous
Environmental Substances, Toxic
Hazardous Materials
Biohazards
Hazardous Substances
Toxic Substances, Environmental
Hazardous Chemicals
Toxic Environmental Substances

Elements, compounds, mixtures, or solutions that are considered severely harmful to human health and the environment. They include substances that are toxic, corrosive, flammable, or explosive.


Pro-C4
Pro-complement 4
Complement Component 4
Complement C4, Precursor
Complement C4
C4 Complement Component
Complement 4
C4 Complement

A glycoprotein that is important in the activation of CLASSICAL COMPLEMENT PATHWAY. C4 is cleaved by the activated COMPLEMENT C1S into COMPLEMENT C4A and COMPLEMENT C4B.


Sulfoxyphenylpyrazolidin Anturan Sulfinpyrazone Apo-Sulfinpyrazone Anturane Nu-Sulfinpyrazone Sulphinpyrazone

A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.


Cephalaria Knautia Succisa Teasel Dipsacus Dipsacaceae Scabiosa

A plant family of the order Dipsacales, subclass Asteridae, class Magnoliopsida. It is sometimes called the teasel family.


Type C Avian Retroviruses
Avian Erythroblastosis Virus
Avian Leukosis-Sarcoma Viruses
Retroviruses Type C, Avian
Alpharetrovirus
Retroviruses, ALV-Related
Erythroblastosis Virus, Avian

A defective avian leukemia virus in the family ALPHARETROVIRUS, causing progressive anemia and weakness in domestic and wild fowl.


Type III Collagen
Collagen alpha1(III)
Type III Procollagen
Procollagen Type III
Collagen Type III, alpha1 Chain
Collagen Type III

A fibrillar collagen consisting of three identical alpha1(III) chains that is widely distributed in many tissues containing COLLAGEN TYPE I. It is particularly abundant in BLOOD VESSELS and may play a role in tissues with elastic characteristics.


Colombian Catfish
Heteropneustes
Siluriformes
Eremophilus mutisii
Catfishes
Arius
Plotosus
Catfish

A fish species of the order SILURIFORMES, family Trichomycteridae.


Perineuronal Satellite Oligodendroglia Cells

Satellite Cells, Perineuronal, Oligodendroglia

A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as SATELLITE CELLS, PERINEURONAL of GANGLIA) according to their location. They form the insulating MYELIN SHEATH of axons in the central nervous system.


Salt Stress Reaction
Salinity Stress Reponse
Salinity Stress
Salt Stress Response
Salinity Stress Reaction
Salt Stress

The condition that results from ion toxicity due to ion imbalances (e.g., excessive Na+ and deficiency in Mg++).


Diketopiperazine Compounds
Piperazinediones
Diketopiperazines
Diketopiperazine
Diketopiperazine Ion (1-)
Pyrrolopiperazinediones
Pyrrolodiketopiperazines


Uteroplacental Circulation
Fetal-Placental Circulation
Fetoplacental Circulation
Placental Circulation
Circulation, Fetoplacental
Circulation, Placental
Circulation, Uteroplacental

The circulation of blood through the uterus and placenta on the maternal side.


Levee Failure
Structure Failure
Building Collapse
Dam Collapse
Bridge Failure
Bridge Collapse
Structure Collapse
Dike Failure
Levee Collapse


Sacrospinalis Spinalis
Interspinales
Paraspinal Muscles
Rotatores
Sacrospinalis Longissimus
Semispinalis
Multifidus
Intertransversarii
Splenius
Intertransversales
Sacrospinalis Iliocostalis
Deep Muscles of the Back
Intrinsic Muscles of the Back

Deep muscles in the BACK whose function is to extend and rotate the SPINE and maintain POSTURE. It consists splenius, semispinalis, multifidus, rotatores, interspinales, intertransversarii and sacrospinalis.


Cohosh, Blue
Caulophyllum thalictroides
Blue Cohosh
Caulophyllum


Ichthyosis, X-Linked
Placental Steroid Sulfatase Deficiency
Steroid Sulfatase Deficiency Disease
Ichthyosis, Sex-Linked
Steroid Sulfatase Deficiency

Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the X-chromosome and transmitted to the male offspring. It is characterized by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency.


Marsdenia tenacissima
Marsdenia condurango
Marsdenia
Condurango

A plant genus of the family ASCLEPIADACEAE. Members contain pregnane glycosides (marsdekoiside & marstomentosides, maryal) and hainaneosides (SAPONINS).


MCM2-7 Complex
MCM Protein Complex
Minichromosome Maintenance Proteins
MCM2-7 Helicase

A hexameric protein complex of minichromosome maintenance proteins.


Symptom Exacerbation
Symptom Flare-up
Symptom Increase
Symptom Flaring Up
Symptom Flareup
Acute Symptom Flare
Symptom Flare Up
Symptom Worsening
Symptom Magnification
Symptom Exaggeration

A transient exacerbation of symptoms of an existing disease or condition.


Abdominal Oblique Muscles
Oblique Muscles, Abdominal
External Abdominal Oblique Muscle
External Oblique Muscle
Internal Oblique Muscle
Internal Abdominal Oblique Muscle

Muscles of the anterolateral abdominal wall consisting of the external oblique and the internal oblique muscles. The external abdominal oblique muscle fibers extend from lower thoracic ribs to the linea alba and the iliac crest. The internal abdominal oblique extend superomedially beneath the external oblique muscles.


Foenumgraecum
Trigonella foenum-graecum
Poenumgraecum
Fenugreek
Trigonella


Autocrine Motility Factor
Glucosephosphate Isomerase
Neuroleukin
Phosphoglucose Isomerase
Glucose-6-Phosphate Isomerase
Isomerase, Glucose 6 Phosphate
Phosphohexose Isomerase
Tumor-Cell Autocrine Motility Factor
Tumor Autocrine Motility Factor

A secreted form of glucose-6-phosphate isomerase.


Dyssynergia Cerebellaris Myoclonica Of Hunt

A condition marked by progressive CEREBELLAR ATAXIA combined with MYOCLONUS usually presenting in the third decade of life or later. Additional clinical features may include generalized and focal SEIZURES, spasticity, and DYSKINESIAS. Autosomal recessive and autosomal dominant patterns of inheritance have been reported. Pathologically, the dentate nucleus and brachium conjunctivum of the CEREBELLUM are atrophic, with variable involvement of the spinal cord, cerebellar cortex, and basal ganglia. (From Joynt, Clinical Neurology, 1991, Ch37, pp60-1)


Pancuronium Bromide
Pancuronium
Pancuronium Organon
Pancuronium Curamed
Pavulon

A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than CURARE but has less effect on the circulatory system and on histamine release.


Acrospiroma, Eccrine
Eccrine Spiradenoma
Nodular Hidradrenoma
Hidradenoma
Solid-Cystic Hidradenoma
Cystic Hidradenoma
Eccrine Acrospiroma
Spiradenoma
Clear-Cell Hidradrenoma
Acrospiroma

A rare cutaneous tumor of apocrine or eccrine SWEAT GLAND origin. It is most commonly found on the extremities and is usually benign. It appears as a solitary nodule or cyst and may be solid or produce a watery discharge. It is related to POROMA except in acrospiroma it does not involve the epidermis. There is no indication that heredity or external agents cause these tumors.


Bazudine Neotsidol Diazinon Dimpylate Neocidol

A cholinesterase inhibitor that is used as an organothiophosphorus insecticide.


Dyskinesias
Orofacial Dyskinesia
Oral Dyskinesia
Tardive Oral Dyskinesia
Involuntary Movements
Lingual-Facial-Buccal Dyskinesia
Ballismus
Linguofacial Dyskinesia
Oral-Facial Dyskinesia
Abnormal Movements
Hemiballism
Asterixis
Hemiballismus

Abnormal involuntary movements which primarily affect the extremities, trunk, or jaw that occur as a manifestation of an underlying disease process. Conditions which feature recurrent or persistent episodes of dyskinesia as a primary manifestation of disease may be referred to as dyskinesia syndromes (see MOVEMENT DISORDERS). Dyskinesias are also a relatively common manifestation of BASAL GANGLIA DISEASES.


Homeless Child
Homeless Children
Street Child
Runaways
Street Youth
Street Children
Homeless Youth

Runaway and homeless children and adolescents living on the streets of cities and having no fixed place of residence.


Mecain
Mepivacaine Hydrochloride
Scandonest
Polocaine
Mepihexal
Isocaine
Mepivacaine
Carbocaine
Carbocaïne
Meaverin
Scandinibsa
Mepivacain-Injektopas
Mepivacaine Monohydrochloride
Isogaine
Mepivastesin
Scandicain
Mepivacaina Braun
Scandicaine

A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)


Activated Leukocyte Cell Adhesion Molecule

Activated-Leukocyte Cell Adhesion Molecule

Cell adhesion molecule expressed on activated leukocytes, fibroblasts, and neurons. It is a ligand for CD6. ALCAM-CD6 interactions may play a role in the binding of T and B cells to activated leukocytes.


Deficiency, Vitamin
Vitamin Deficiency
Avitaminosis

A condition due to a deficiency of one or more essential vitamins. (Dorland, 27th ed)


Dental Prosthesis Coloring
Prosthesis Coloring, Dental
Coloring, Dental Prosthesis
Prosthesis Coloring

Coloring, shading, or tinting of prosthetic components, devices, and materials.


Tetras Characidae Characids Characins Tetragonopterus

A family of fresh water fish in the order CHARACIFORMES, which includes the Tetras.


Switching Complex
Switch Genes
Switch Complexes
Switching Complexes
Genes, Switch

Genes that cause the epigenotype (i.e., the interrelated developmental pathways through which the adult organism is realized) to switch to an alternate cell lineage-related pathway. Switch complexes control the expression of normal functional development as well as oncogenic transformation.


Medical Home
Patient-Centered Nursing
Patient-Centered Care
Patient-Focused Care
Nursing, Patient-Centered

Ongoing integrated provision of care and services focused on the needs of the individual including preventive, ambulatory, and acute hospital-based.


Elaeagnus
Olive, Russian
Buffaloberry
Elaeagnaceae
Shepherdia

A plant family of the order Rhamnales, subclass Rosidae class Magnoliopsida. The plants have a characteristic silvery or rusty-colored sheen, caused by tiny distinctive scales. Flowers have a tubular structure of four sepals. Root nodules host the Frankia (ACTINOMYCETES) nitrogen-fixing symbionts.


Kisspeptin-1
Metastasis Suppressor KiSS-1
KiSS-1 Metastasis Suppressor
Metastins
Kisspeptins

Intercellular signaling peptides that were originally characterized by their ability to suppress NEOPLASM METASTASIS. Kisspeptins have since been found to play an important role in the neuroendocrine regulation of REPRODUCTION.


Hearing Loss, Central
Deafness Neurosensory
Central Hearing Loss
Deafness, Cortical
Cortical Deafness

Hearing loss due to disease of the AUDITORY PATHWAYS (in the CENTRAL NERVOUS SYSTEM) which originate in the COCHLEAR NUCLEI of the PONS and then ascend bilaterally to the MIDBRAIN, the THALAMUS, and then the AUDITORY CORTEX in the TEMPORAL LOBE. Bilateral lesions of the auditory pathways are usually required to cause central hearing loss. Cortical deafness refers to loss of hearing due to bilateral auditory cortex lesions. Unilateral BRAIN STEM lesions involving the cochlear nuclei may result in unilateral hearing loss.


Growth-Associated Proteins, Neuronal
Neuronal Growth-Associated Proteins
Neurotrophic Proteins
Neuronotrophic Factors
Neurotrophins
Neurite Outgrowth Factors
Proteins, Neuronal Growth-Associated
Nerve Growth Factors
Neurotrophic Protein
Neurotrophic Factors

Factors which enhance the growth potentialities of sensory and sympathetic nerve cells.


Vascular Medicine
Cardiology
Cardiovascular Disease Specialty
Angiology

The study, diagnosis, and treatment of diseases of the blood vessels (VASCULAR DISEASES) and vessels of lymphatic system (LYMPHATIC DISEASES).


Pituitary Carcinoma
Pituitary Cancer
Pituitary Adenoma
Pituitary Neoplasms
Cancer of the Pituitary
Cancer of Pituitary
Pituitary Tumors

Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.


Protein Tyrosine Phosphatase, Receptor Type, C

A splicing isoform of CD45 antigen that includes exon A.


Ayurvedic Medicine
Medicine, Hindu
Hindu Medicine
Medicine, Ayurvedic
Siddha Medicine

A derivative of Ayurveda Rasashastra alchemy.


Bacillus amyloliquefaciens Serine Protease

A family of SERINE ENDOPEPTIDASES isolated from Bacillus subtilis. EC 3.4.21.-


Neopallium
Neopallial Cortex
Neocortical External Pyramidal Layer
Cerebral Neocortex
Neocortical Internal Granular Layer
Isocortex
Substantia Corticalis
Neocortical Multiform Layer
Neocortical Internal Pyramidal Layer
External Granular Layer
Neocortical External Granular Layer
Neocortical Molecular Layer
Neocortex

The largest portion of the CEREBRAL CORTEX in which the NEURONS are arranged in six layers in the mammalian brain: molecular, external granular, external pyramidal, internal granular, internal pyramidal and multiform layers.


Neoplasms, Gastric
Gastric Neoplasms
Gastric Cancer
Cancer of the Stomach
Stomach Neoplasms
Neoplasms, Stomach
Cancer of Stomach
Gastric Cancer, Familial Diffuse
Stomach Cancer


Biologic Waste Disposal
Disposal, Infectious Waste
Waste Disposal, Pathological
Waste Disposal, Infectious
Disposal, Biological Waste
Waste Disposal, Medical
Infectious Waste Disposal
Medical Waste Disposal
Disposal, Pathological Waste
Biological Waste Disposal
Specimen Disposal
Pathological Waste Disposal
Disposal, Medical Waste
Waste Disposal, Biological

Management, removal, and elimination of biologic, infectious, pathologic, and dental waste. The concept includes blood, mucus, tissue removed at surgery or autopsy, soiled surgical dressings, and other materials requiring special control and handling. Disposal may take place where the waste is generated or elsewhere.


Duck Gait
Gait, Frontal
Gait, Shuffling
Sensorimotor Gait Disorder
Gait, Festinating
Gait, Hysterical
Gait, Drop Foot
Rapid Fatigue of Gait
Gait, Hemiplegic
Neurologic Locomotion Disorders
Gait, Athetotic
Gait, Reeling
Gait, Unsteady
Charcot's Gait
Gait Dysfunction, Neurologic
Gait, Scissors
Neurologic Ambulation Disorders
Marche a Petit Pas
Ambulation Disorders, Neurologic
Gait Disorder, Sensorimotor
Gait Disorders, Neurologic
Gait, Stumbling
Charcot Gait
Locomotion Disorders, Neurologic
Gait, Rigid
Gait, Broadened
Gait, Spastic
Gait, Widebased

Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES.


Rhaponticum
Leuzea carthamoides
Rhaponticum carthamoides
Leuzea

A plant genus of the family ASTERACEAE. ECDYSONE has been found in seeds of some members.


Bestrophin-1
BEST-1 Protein
Bestrophin-2
BEST-2 Protein
Bestrophin Proteins
Bestrophin Family
Bestrophins

A protein family characterized by a highly conserved N-terminus and four to six transmembrane helices; they function as bicarbonate permeable, calcium-activated chloride channels. Bestrophin-1 (BEST-1) and bestrophin-2 are highly expressed in human RETINAL PIGMENT EPITHELIUM cells and mutations in the BEST-1 gene are associated with VITELLIFORM MACULAR DYSTROPHY, TYPE 2.


Service, British National Health
Medicine, State
British Health Service, National
National Health Service, British
State Medicine
British National Health Service
Socialized Medicine
Medicine, Socialized

A system of medical care regulated, controlled and financed by the government, in which the government assumes responsibility for the health needs of the population.


Loeffler's Endocarditis
Endocarditis, Loeffler's
Loeffler Endocarditis
Leukemia, Eosinophilic
Hypereosinophilic Syndrome
Endocarditis, Loeffler
Idiopathic Hypereosinophilic Syndrome
Hypereosinophilic Syndrome, Idiopathic

A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.


Jockey Elements
LINE Repeat Sequences
Long Interspersed DNA Sequence Elements
Long Interspersed Nucleotide Elements
LINE-1 Elements
L1 Elements

Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is related to the reverse transcriptase of retroviruses but they do not contain LTRs (long terminal repeats). Copies of the LINE 1 (L1) family form about 15% of the human genome. The jockey elements of Drosophila are LINEs.


Patient Hand Over
Patient Sign Outs
Patient Sign Out
Patient Signover
Nursing Handoff
Nursing Hand Over
Patient Hand Offs
Nursing Hand Overs
Clinical Handover
Patient Hand Overs
Nursing Handover
Clinical Handoffs
Nursing Hand Off
Patient Hand Off
Patient Handoff
Nursing Hand Offs
Patient Handover
Patient Signout

Transfers within a facility between clinical locations (eg, ICU to the step-down unit) and disciplines (eg, cardiology to cardiac surgery) in addition to within a discipline (eg, cross-coverage by residents, nurses, or attending physicians).


Veterinary Hospitals
Veterinary Clinics
Hospitals, Veterinary
Hospitals, Animal
Clinics, Veterinary
Animal Hospitals

Facility for in-house medical care of animals.


Patient Reported Outcome Measures
Patient Reported Outcomes
Patient Reported Outcome

Assessment of the quality and effectiveness of health care as measured and directly reported by the patient.


Methoxyverapamil
Gallopamil
gallopamil von ct
Elgiprona
Prebet
D-600
Procorum
Gallobeta
Gallopamil Hydrochloride
D600

Coronary vasodilator that is an analog of iproveratril (VERAPAMIL) with one more methoxy group on the benzene ring.


Congenital Toxoplasmosis
Congenital Toxoplasma Infections
Congenital Toxoplasma gondii Infection
Toxoplasmosis, Prenatal
Congenital Infection, Toxoplasma gondii
Toxoplasma Infections, Congenital
Toxoplasmosis, Congenital
Toxoplasmosis, Fetal

Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)


Protein Subunit
Protein Subunits
Protomer
Protomers

Substructures of multimeric PROTEINS. They may be monomeric or heterodimeric substructures.


Water Buffalo
Bubalus
Buffaloes
Water Buffaloes
Syncerus
Buffalo

Ruminants of the family Bovidae consisting of Bubalus arnee and Syncerus caffer. This concept is differentiated from BISON, which refers to Bison bison and Bison bonasus.


A type II keratin found expressed in the upper spinous layer of epidermal KERATINOCYTES. Mutations in genes that encode keratin-2A have been associated with ICHTHYOSIS BULLOSA OF SIEMENS.


A dacarbazine derivative that is used as an alkylating antineoplastic agent for the treatment of MALIGNANT GLIOMA and MALIGNANT MELANOMA.


Reversible Posterior Leukoencephalopathy Syndrome

Posterior Reversible Encephalopathy Syndrome

A condition that is characterized by HEADACHE; SEIZURES; and visual loss with edema in the posterior aspects of the CEREBRAL HEMISPHERES, such as the BRAIN STEM. Generally, lesions involve the white matter (nerve fibers) but occasionally the grey matter (nerve cell bodies).


Frog adenovirus
Turkey adenovirus 3
Turkey adenovirus A
Marble spleen disease virus
Siadenovirus


Ureaplasma urealyticum biovar 1
T-Mycoplasma
Ureaplasma parvum
Ureaplasma

A species of UREAPLASMA containing four serovars formerly classed as UREAPLASMA UREALYTICUM. Those serovars are 1, 3, 6, and 14.


Stored Messenger RNA
RNA, Messenger, Maternal
Masked mRNA
RNA, Messenger, Paternal
Stored mRNA
Maternal Messenger RNA
Masked Messenger RNA
Paternal mRNA
RNA, Messenger, Stored
RNA, Messenger, Masked
Maternal mRNA
Paternal Messenger RNA

Messenger RNA derived from the paternal genome during spermatogenesis. It is stored in a masked state for translation in the early stages of embryogenesis.


Licensure, Institutional, Personnel
Licensing
Licensure
Licenses
Permits
Institutional Personnel Licensure

The legal authority or formal permission from authorities to carry on certain activities which by law or regulation require such permission. It may be applied to licensure of institutions as well as individuals.


Cancer of the Vulva
Cancer of Vulva
Neoplasms, Vulvar
Vulvar Cancer
Vulvar Neoplasms
Vulva Cancer
Vulva Neoplasms


Urogenital Cancer
Genito-urinary Cancer
Urogenital Neoplasms
Genito-urinary Neoplasm
Genitourinary Neoplasms
Neoplasms, Genitourinary
Genitourinary Cancer
Neoplasms, Urogenital

Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.


Privacy of Patient Data
Secrecy
Privileged Communication
Patient Data Privacy
Confidential Information
Confidentiality

In law, a confidential statement made to a lawyer, physician, pastor, or spouse, which is privileged against disclosure in court if the privilege is claimed by the client, patient, penitent, or spouse. (Bioethics Thesaurus)


Ak-Tracin
Bacitracin Zinc Complex
Baci-IM
Altracin
Ocu-Tracin
Zinc Bacitracin
Baciguent
Bacitin
Bacitracine Martinet
Zeba-Rx
Bacitracin
Topitracin
Baci-Rx
Bacitracin Zinc

A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The commercial preparation is a mixture of at least nine bacitracins with bacitracin A as the major constituent. It is used topically to treat open infections such as infected eczema and infected dermal ulcers. (From Goodman and Gilman, The Pharmacological Basis of Therapeutics, 8th ed, p1140)


EloB Protein
Transcription Factor SIII
Elongin
EloA Protein
EloC Protein
Elongin A
Elongin B
TF-SIII
Elongin Complex
Elongin C
SIII Elongation Factor

A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity.


FMR1-Related Primary Ovarian Insufficiency

Hypergonadotropic Ovarian Failure, X-Linked

Primary Ovarian Insufficiency, Fragile X-Associated

X-Linked Hypergonadotropic Ovarian Failure

Fragile X-Associated Primary Ovarian Insufficiency

A form of ovarian failure, caused by resistance to GONADOTROPINS stimulation. It may be caused by defects in the receptors for FOLLICLE STIMULATING HORMONE or LUTEINIZING HORMONE. It may be due to factors interfering with the actions of gonadotropins, such as antibodies blocking the ligand-receptor interaction.


ATPases Associated with Diverse Cellular Activities

A large highly-conserved family of ATPases with diverse functions in cells that are characterized by the presence of a P-LOOP and a ring shape. They couple the energy generated by ATP hydrolysis to remodeling or mechanical translocation of their target molecules.