Ocular Headache
Bilateral Headache
Generalized Headache
Cephalgia
Headache
Hemicrania
Head Pain
Vertex Headache
Retro-Ocular Headache
Periorbital Headache
Unilateral Headache
Throbbing Headache
Cephalodynia
Cephalalgia
Sharp Headache
Cranial Pain
Orthostatic Headache

The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.


Yew, Harrington Plum
Cephalotaxus harringtonia
Cephalotaxus

A plant genus of the family TAXACEAE, order Pinales, class Pinopsida, division TRACHEOPHYTA. Members contain homoharringtonine.


Fluvoxamin beta
Fluvoxamin-neuraxpharm
Fluvoxamina Geminis
PMS-Fluvoxamine
DU-23000
Novo-Fluvoxamine
Fluvoxamin AL
Fevarin
Fluvoxamine
ratio-Fluvoxamine
Fluvoxamine Maleate, (E)-Isomer
Fluvoxamine, (Z)-Isomer
Fluvoxadura
Fluvoxamin Stada
Faverin
Floxyfral
Dumirox
Nu-Fluvoxamine
Fluvoxamine Maleate
Fluvoxamin-ratiopharm
Desiflu
Luvox

A selective serotonin reuptake inhibitor that is used in the treatment of DEPRESSION and a variety of ANXIETY DISORDERS.


Circovirus, Porcine
Beak and feather disease virus
Porcine Circovirus
Circovirus

A genus of the family CIRCOVIRIDAE that infects SWINE; PSITTACINES; and non-psittacine BIRDS. Species include Beak and feather disease virus causing a fatal disease in psittacine birds, and Porcine circovirus causing postweaning multisystemic wasting syndrome in pigs (PORCINE POSTWEANING MULTISYSTEMIC WASTING SYNDROME).


An indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and  MONOAMINE OXIDASE to prolong the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals and may be a neurotransmitter in some invertebrate nervous systems.


Otogenic Vertigo
Meniere Disease
Vertigo, Aural
Meniere's Syndrome
Aural Vertigo
Ménière's Vertigo
Ménière Disease
Auditory Vertigo
Ménière's Disease
Meniere's Disease

A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.


Insulinoma Amyloid Polypeptide Precursor

A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.


Interatrial Conduction Delay
Bayes' Syndrome
Bayes Syndrome
Interatrial Block

Impaired or delayed impulse conduction between the right and left HEART ATRIA. Advanced interatrial blocks are often associated with arrhythmias (e.g., ATRIAL FLUTTER; and ATRIAL FIBRILLATION), direct conduction block via the Bachmann's bundle and concomitant left atrial enlargement. Syndrome of advanced interatrial block associated with SUPRAVENTRICULAR TACHYCARDIA is referred to as Bayes syndrome.


A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.


Corneal Surgery, Laser
Laser Corneal Surgery
Keratectomy, Laser
Photokeratectomy
Laser Keratectomy

Surgical techniques on the CORNEA employing LASERS, especially for reshaping the CORNEA to correct REFRACTIVE ERRORS.


Demetrin
Lysanxia
Mono Demetrin
Centrax
Prazepam
Reapam

A benzodiazepine that is used in the treatment of ANXIETY DISORDERS.


Lipolysis, Suction
Lipoplasty
Aspiration Lipectomy
Liposuction
Suction Lipectomy
Aspiration Lipolysis
Lipectomy

Removal of localized SUBCUTANEOUS FAT deposits by SUCTION CURETTAGE or blunt CANNULATION in the cosmetic correction of OBESITY and other esthetic contour defects.


A group of related enzymes responsible for the endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose-content glycopeptides and GLYCOPROTEINS.


Nodular Heterotopia, Bilateral Periventricular

Bilateral Periventricular Nodular Heterotopia

Heterotopia, Periventricular, X-Linked Dominant

A disorder resulting from a defect in the pattern of neuronal migration in which ectopic collections of neurons lie along the lateral ventricles of the brain or just beneath, contiguously or in isolated patches.


Bean, Kidney
Tepary Bean
Common Bean Plant
Bean, Tepary
Phaseolus vulgaris
French Bean Plant
Phaseolus
Kidney Bean
Phaseolus acutifolius

Edible beans from Phaseolus acutifolius.


Adenovirus Early Region Transforming Proteins

Proteins encoded by adenoviruses that are synthesized prior to, and in the absence of, viral DNA replication. The proteins are involved in both positive and negative regulation of expression in viral and cellular genes, and also affect the stability of viral mRNA. Some are also involved in oncogenic transformation.


Indian Elecampane
Inula helenium
Pushkarmula
Pushkarmoola
Elecampane
Inula
Inula racemosa

A plant genus of the family ASTERACEAE. Members contain INULIN, alantol, helenin, alantic acid, and acrid resin.


A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.


Parathyroid Neoplasms
Cancer of the Parathyroid
Parathyroid Cancer
Parathyroid Adenoma
Neoplasms, Parathyroid
Cancer of Parathyroid
Parathyroid Carcinoma

Tumors or cancer of the PARATHYROID GLANDS.


Heschl's Gyri
Heschl's Convolutions
Temporal Auditory Area
Auditory Cortex
Transverse Temporal Gyri
Primary Auditory Cortex
Auditory Area

The region of the cerebral cortex that receives the auditory radiation from the MEDIAL GENICULATE BODY.


Conferences and Congresses
Congresses as Topic
Conferences and Proceedings
Congresses and Conferences
Professional Meetings and Conferences
Conferences
Conference Proceedings as Topic

Works about conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.


Rat Kangaroo
Potoroo
Bettongia
Long-Nosed Potoroo
Long-Nosed Rat Kangaroo
Potoroidae
Potorous tridactylus

Species of potoroo in the genus Potorous, family Potoroidae.


Emergency Medical Dispatcher
9-1-1 Dispatcher
911 Dispatcher

Professionals responsible for relaying calls for the deployment of EMERGENCY MEDICAL SERVICES.


Cavity Lining, Dental
Cavity Linings, Dental
Cavity Liner, Dental
Dental Cavity Lining
Cavity Lining Varnish
Dental Cavity Liner
Liners, Dental Cavity
Linings, Dental Cavity
Lining, Dental Cavity
Dental Cavity Linings
Dental Cavity Liners
Varnish, Cavity
Cavity Lining Varnishes
Cavity Varnishes

An inner coating, as of varnish or other protective substance, to cover the dental cavity wall. It is usually a resinous film-forming agent dissolved in a volatile solvent, or a suspension of calcium hydroxide in a solution of a synthetic resin. The lining seals the dentinal tubules and protects the pulp before a restoration is inserted. (Jablonski, Illustrated Dictionary of Dentistry, 1982)


Choledochal Cyst, Type III
Intrahepatic Choledochal Cyst
Cyst, Common Bile Duct
Cysts, Common Bile Duct
Choledochal Cyst, Type I
Choledochal Cyst, Type V
Multiple Choledochal Cysts
Choledochal Cyst, Type IV
Bile Duct Cysts
Choledochal Cyst, Type II
Congenital Biliary Dilatation
Choledochal Diverticulum
Choledochal Cyst
Congenital Choledochal Cyst
Choledochocele
Choledochal Cyst, Diverticulum
Common Bile Duct Cyst

Characterized by the presence of multiple extrahepatic and intrahepatic cysts.


Neuroprotectants
Neuroprotective Drugs
Neuroprotective Agents
Neuroprotective Effects
Neuroprotective Effect

Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.


Monkshood
Aconite
Radix Aconiti
Aconitum
Aconitum napellus


A plant genus of the family SAURURACEAE. Members contain aristolactams.


Cancer of Skin
Skin Cancer
Neoplasms, Skin
Cancer of the Skin
Skin Neoplasms


meta-Aminobenzoic Acid Derivatives
meta-Aminobenzoates
m-Aminobenzoates
5-Aminobenzoates
meta-Aminobenzoic Acids
3-Aminobenzoates
5-Aminobenzoic Acid Derivatives
3-Aminobenzoic Acids
3-Aminobenzoic Acid Derivatives
5-Aminobenzoic Acids

Aminobenzoate derivatives that contain an amino group attached to carbon number 3 or 5 of the benzene ring structure.


Neckache
Anterior Neck Pain
Posterior Neck Pain
Neck Pain
Cervicalgia
Cervicodynia
Neck Ache
Posterior Cervical Pain
Anterior Cervical Pain
Cervical Pain

Discomfort or more intense forms of pain that are localized to the cervical region. This term generally refers to pain in the posterior or lateral regions of the neck.


Granulocyte-Macrophage Colony Forming Units

The parent cells that give rise to both cells of the GRANULOCYTE lineage and cells of the monocyte/macrophage lineage.


A uridine monophosphate analog inhibitor of HEPATITIS C VIRUS (HCV) polymerase NS5B that is used as an ANTIVIRAL AGENT in the treatment of CHRONIC HEPATITIS C.


Ectodermal Dysplasia, Hidrotic, Autosomal Dominant

Clouston's Hidrotic Ectodermal Dysplasia

Hidrotic Ectodermal Dysplasia, Autosomal Dominant

Autosomal Dominant Hidrotic Ectodermal Dysplasia

A group of hereditary disorders involving tissues and structures derived from the embryonic ectoderm. They are characterized by the presence of abnormalities at birth and involvement of both the epidermis and skin appendages. They are generally nonprogressive and diffuse. Various forms exist, including anhidrotic and hidrotic dysplasias, FOCAL DERMAL HYPOPLASIA, and aplasia cutis congenita.


Genista tinctoria
Gorse, Spanish
Genista
Broom, Dyers
Genista hispanica

A plant genus of the family FABACEAE. The common name of broom may be confused with Scotch Broom (CYTISUS) or Butcher's Broom (RUSCUS) or Desert Broom (BACCHARIS) or Spanish Broom (SPARTIUM) or Brome (BROMUS).


A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)


Nanocrystals, Semiconductor
Quantum Dots
Semiconductor Nanocrystals
Semiconductor Nanoparticles

Nanometer sized fragments of semiconductor crystalline material which emit PHOTONS. The wavelength is based on the quantum confinement size of the dot. They can be embedded in MICROBEADS for high throughput ANALYTICAL CHEMISTRY TECHNIQUES.


The R-isomer of lansoprazole that is used to treat severe GASTROESOPHAGEAL REFLUX DISEASE.


Intracellular Calcium-Sensing Proteins
Calcium-Sensing Peptides, Intracellular
Intracellular Calcium-Sensing Peptides
Calcium-Sensing Proteins, Intracellular

Intracellular signaling peptides and proteins that bind to CALCIUM. They undergo allosteric changes when bound to CALCIUM that affects their interaction with other signal-transducing molecules. They differ from CALCIUM-SENSING RECEPTORS which sense extracellular calcium levels.


Thioredoxins
Thioredoxin 2
Thioredoxin
Thioredoxin-1
Thioredoxin-2
Thioredoxin 1

Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.


Roxihexal
RU 965
roxidura
Roxi-Puren
Claramid
Roxithro-Lich
Rotesan
Biaxsig
Roxi 1A Pharma
Roxi-paed 1A Pharma
Roxi-saar
Roxi TAD
Rotramin
Rulid
Roxi-Q
Roxigrün
Roxithromycin
MTW-Roxithromycin
Roxi Basics
Macrosil
RU-28965
Infectoroxit
RU-965
Rulide
roxi von ct
RU 28965
Roxigamma
Roxibeta
Roxi-Wolff

Semisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive intracellularly. While the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.


Vincetoxicum
Cynanchum atratum
Vincetoxicum atratum

A plant genus of the dogbane family ASCLEPIADACEAE.


bcl-X(L) Protein
bcl-Xb Protein
bcl2L1 Protein
bcl-Xshort Protein
bcl2-Like 1 Protein
bcl-XS Protein
bcl-XL Protein
bcl-Xbeta Protein
bcl-X(S) Protein
bcl-x(beta) Protein
bcl-Xa Protein
bcl-X Protein
bcl-Xalpha Protein
bcl-Xlong Protein

Bcl-XL is an anti-apoptotic protein that is the long isoform of Bcl-X protein. Bcl-XL localizes to the outer mitochondrial membrane and is overexpressed in most human NEOPLASMS. It has also been implicated in ISCHEMIC HEART DISEASE.


Exon Shuffling, In Vitro
Molecular Breeding
DNA Shuffling
In Vitro Exon Shuffling

The use of DNA recombination (RECOMBINATION, GENETIC) to prepare a large gene library of novel, chimeric genes from a population of randomly fragmented DNA from related gene sequences.


Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates.


DNA Primase
Bacteriophage T7 Gene 4 Protein
DnaG Protein
DnaG Gene Product
T7 DNA-Priming Protein
T7 DNA Primase-Helicase Protein
T7 gene-4 protein
Primase
DnaG (Primase)

A single-stranded DNA-dependent RNA polymerase that functions to initiate, or prime, DNA synthesis by synthesizing oligoribonucleotide primers. EC 2.7.7.-.


Psychomotor Disorders
Psychomotor Disorders, Developmental
Developmental Psychomotor Disorders
Psychomotor Impairment

Abnormalities of motor function that are associated with organic and non-organic cognitive disorders.


Hedgehog Protein, Vertebrate
Desert Hedgehog Protein
Sonic Hedgehog Protein
Hedgehog Proteins
Indian Hedgehog Protein
Vertebrate Hedgehog Protein
Banded Hedgehog Protein

A family of intercellular signaling proteins that play an important role in regulating the development of many TISSUES and organs. Their name derives from the observation of a hedgehog-like appearance in DROSOPHILA embryos with genetic mutations that block their action.


Family of electric rays, containing one genus (TORPEDO).


Dew Itch
Creeping Eruption
Larva Migrans, Ocular
Ground Itch
Larva Migrans
Ocular Larva Migrans
Larva Migrans, Cutaneous
Cutaneous Larva Migrans

Infections caused by nematode larvae which never develop into the adult stage and migrate through various body tissues. They commonly infect the skin, eyes, and viscera in man. Ancylostoma brasiliensis causes cutaneous larva migrans. Toxocara causes visceral larva migrans.


Costs and Cost Analyses
Pricing
Costs and Cost Analysis
Cost Comparison
Cost Measures
Costs, Cost Analysis
Analysis, Cost
Cost Analysis
Affordability
Cost-Minimization Analysis
Cost

The cost of goods or services in context of the expected benefit for the consumer and the means available to that consumer.


Furanoeremophilane Derivatives
Furanoeudesmanes
Sesquiterpenes, Eudesmane
Furanoeremophilanes
Eudesmane Derivatives
Furanoeudesmane Derivatives
Eudesmanes

SESQUITERPENES cyclized into two adjoining cyclohexane rings but with a different configuration from the ARTEMISININS.


Neoplasms, Salivary Gland
Salivary Gland Neoplasms
Salivary Gland Cancer
Cancer of Salivary Gland
Cancer of the Salivary Gland

Tumors or cancer of the SALIVARY GLANDS.


Secondary Somatosensory Area
Second Somatic Sensory Area
Anterior Parietal Cortex
Primary Somatosensory Cortex
SI Cortex
Secondary Sensory Cortex
Post Central Gyrus
Postcentral Gyrus
Primary Somatosensory Area
Gyrus Postcentralis
Primary Somatosensory Areas
Secondary Somatosensory Cortex
Somatosensory Cortex
Primary Somatic Sensory Area

Area of the parietal lobe concerned with receiving sensations such as movement, pain, pressure, position, temperature, touch, and vibration. It lies posterior to the central sulcus.


Palmitoylcarnitine Transferase
Carnitine Palmitoyltransferase I
CPT II
Carnitine O-Palmitoyltransferase
Palmitylcarnitine Acyltransferase
Carnitine Acyltransferase I
Carnitine Palmitoyltransferase
Carnitine Palmitoyltransferase II

An enzyme that catalyzes reversibly the conversion of palmitoyl-CoA to palmitoylcarnitine in the inner mitochondrial membrane. EC 2.3.1.21.


Idiopathic Diffuse Interstitial Pulmonary Fibrosis

A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.


A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.


Thrombosis, Carotid
Common Carotid Artery Thrombosis
Thrombosis, Internal Carotid Artery
Thrombosis, Carotid Artery
External Carotid Artery Thrombosis
Carotid Artery Thrombosis
Carotid Thrombosis
Thrombosis, Common Carotid Artery
Internal Carotid Artery Thrombosis
Thrombosis, External Carotid Artery

Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.


Palliative Nursing
Palliative Care Nursing
Hospice Nursing
Hospice and Palliative Care Nursing

A nursing specialty concerned with care of patients facing serious or life-threatening illnesses. The goal of palliative nursing is to prevent and relieve suffering, and to support the best possible quality of life for patients and their families. Hospice nursing is palliative care for people in their final stages of life.


Cricoarytenoid Muscles
Arytenoid Muscle
Thyroepiglottic Muscle
Cricothyroid Muscles
Laryngeal Muscles
Vocalis Muscle
Thyroarytenoid Muscles
Vocal Muscle
Aryepiglottic Muscle

The striated muscle groups which move the LARYNX as a whole or its parts, such as altering tension of the VOCAL CORDS, or size of the slit (RIMA GLOTTIDIS).


The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.


Textiloma
Retained Surgical Sponge
Retained Surgical Items
Retained Surgical Needle
Retained Surgical Instruments
Foreign Bodies
Gossypiboma
Foreign Objects
Retained Surgical Tools

Accidentally retained SURGICAL SPONGES after surgery.


Mononeuropathy Multiplex Syndrome
Mononeuritis
Mononeuropathies
Mononeuritis Multiplex
Mononeuropathy Multiplex

Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ISCHEMIA; traumatic injury; compression; CONNECTIVE TISSUE DISEASES; CUMULATIVE TRAUMA DISORDERS; and other conditions.


Innovation, Organizational
Organizational Innovation
Change, Organizational
Organizational Change

Introduction of changes which are new to the organization and are created by management.


Domestic Polecats
Ferrets
European Polecats
Mustela putorius
Mustela putorius furo

Semidomesticated variety of European polecat much used for hunting RODENTS and/or RABBITS and as a laboratory animal. It is in the subfamily Mustelinae, family MUSTELIDAE.


Guinea pig cytomegalovirus
Roseolovirus
Caviid herpesvirus 2

A cytomegalovirus species in the family ROSEOLOVIRUS, infecting guinea pigs.


Encephalomyelitis, Acute Necrotizing Hemorrhagic

A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5)


Left-Right Determination Factor Proteins

Signaling ligands that act in opposition to NODAL PROTEIN. During vertebrate development they regulate the degree of left-right asymmetry by controlling the spatiotemporal influence of NODAL PROTEIN.


Foodborne Diseases
Food-borne Illnesses
Food Poisoning
Poisoning, Food
Foodborne Illnesses
Food-borne Diseases

Acute illnesses, usually affecting the GASTROINTESTINAL TRACT, brought on by consuming contaminated food or beverages. Most of these diseases are infectious, caused by a variety of bacteria, viruses, or parasites that can be foodborne. Sometimes the diseases are caused by harmful toxins from the microbes or other chemicals present in the food. Especially in the latter case, the condition is often called food poisoning.


Spastic Dysphonia, Neurologic Adducter
Spastic Dysphonia
Dysphonia
Neurologic Adducter Spastic Dysphonia
Phonation Disorders
Organic Tremor Dysphonia
Hyperkinetic Dysphonia

Difficulty and/or pain in PHONATION or speaking.


Side Effects, Psychological
Psychological Factors
Psychosocial Factors
Psychology
Psychological Side Effects
Psychologists
Factors, Psychological

The science dealing with the study of mental processes and behavior in man and animals.


Indian Tobacco
Lobelia
Lobelia laxiflora
Lobelia inflata
Sierra Madre Lobelia

A plant genus of the family CAMPANULACEAE used medicinally and is a source of LOBELINE.


Proluton Depot
Hydroxyprogesterone Caproate
17-alpha-Hydroxy-Progesterone Caproate
Makena
17 alpha-Oxyprogesterone Capronate
Prolutin Depot
17 alpha-Hydroxyprogesterone Caproate
Oxyprogesterone Caproate
Hydroxyprogesterone Hexanoate
Neolutin
17-Hydroxyprogesterone Capronate
Delalutin

Hydroxyprogesterone derivative that acts as a PROGESTIN and is used to reduce the risk of recurrent MISCARRIAGE and of PREMATURE BIRTH. It is also used in combination with ESTROGEN in the management of MENSTRUATION DISORDERS.


GRB2 Adaptor Protein, Grb3-3 Isoform
Abundant Src Homology Protein
GRB2 Adaptor Protein
Growth Factor Receptor-Bound Protein-2
Grb3-3 Adaptor Protein

Grb3-3 is a natural isoform of GRB2 PROTEIN with a deletion in the SH2 DOMAIN. It acts as a dominant negative protein over GRB2, suppressing proliferative signals. It has also been implicated in APOPTOSIS.


Endometrioid Adenocarcinoma
Adenocarcinoma, Endometrioid
Carcinoma, Endometrioid

An adenocarcinoma characterized by the presence of cells resembling the glandular cells of the ENDOMETRIUM. It is a common histological type of ovarian CARCINOMA and ENDOMETRIAL CARCINOMA. There is a high frequency of co-occurrence of this form of adenocarcinoma in both tissues.


Minke Whale
Balaenoptera acutorostrata bonaerensis
Balaenoptera bonaerensis
Balaenoptera acutorostrata

The form of the MINKE WHALE, which some consider a subspecies, found in the southern hemisphere especially in the ANTARCTIC REGIONS. It is distinguishable by the lack of a white band on each flipper.


White Spots
Dental Decay
Dental White Spots
Caries, Dental
Decay, Dental
Dental Caries
Dental White Spot
Carious Dentin
White Spot, Dental
White Spots, Dental

Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.


Infarction, Anterior Cerebral Artery Circulation

Infarction, Anterior Cerebral Artery Distribution

NECROSIS occurring in the ANTERIOR CEREBRAL ARTERY system, including branches such as Heubner's artery. These arteries supply blood to the medial and superior parts of the CEREBRAL HEMISPHERE, Infarction in the anterior cerebral artery usually results in sensory and motor impairment in the lower body.


Eskazole
Gascop
Mediamix V Disthelm
Albendoral
SK&F-62979
Zentel
SKF-62979
Albendazole Monohydrochloride
Albendazole
Metiazol
Bendapar
Bilutac
Albenza
Lurdex
Valbazen
Digezanol
Disthelm
Andazol
Endoplus

A benzimidazole broad-spectrum anthelmintic structurally related to MEBENDAZOLE that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)


Telomerase Reverse Transcriptase Catalytic Subunit

An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.


Cancer of Pelvis
Pelvis Cancer
Pelvis Neoplasms
Neoplasms of Pelvis
Pelvic Neoplasms
Cancer of the Pelvis
Pelvic Cancer


Hepatitis, Chronic
Cryptogenic Chronic Hepatitis
Hepatitis, Chronic Active
Hepatitis, Chronic Persistent
Hepatitis, Chronic, Cryptogenic
Chronic Hepatitis

A mild form of chronic hepatitis causing limited damage to the liver.


Taurine Deoxycholate
Taurodeoxycholate
Taurodeoxycholic Acid
Deoxycholyltaurine
Sodium Taurodeoxycholate

A bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.


Arterial Diseases, Intracranial
Brain Disorders, Arterial
Arterial Diseases, Brain
Intracranial Arterial Diseases
Intracranial Arterial Disorders
Brain Diseases, Arterial
Arterial Brain Diseases

Pathological conditions involving ARTERIES in the skull, such as arteries supplying the CEREBRUM, the CEREBELLUM, the BRAIN STEM, and associated structures. They include atherosclerotic, congenital, traumatic, infectious, inflammatory, and other pathological processes.


Arctocebus
Loris Genus
Pottos
Perodicticus potto
Loris, Slow
Lorisidae
Genus Loris
Perodicticinae
Angwantibos
Lorisinae
Slender Lorises
Nycticebus
Slow Lorises
Perodicticus

A family of Primates of the suborder Strepsirhini containing four genera. The family is distributed in parts of Africa and Southeast Asian. The four genera are: Arctocebus (angwantibos) and Perodicticus (pottos) in the subfamily Perodicticinae and Loris (slender lorises) and Nycticebus (slow lorises) in the subfamily Lorisinae. All are arboreal and nocturnal. Genus GALAGO is now classified in the family GALAGIDAE.


Arenavirus Infections
Infections, Arenaviridae
Infections, Arenavirus
Arenaviridae Infections

Virus diseases caused by the ARENAVIRIDAE.


Phosphatidylinositol 4,5-Bisphosphate 5-Phosphatase Deficiency

A sex-linked recessive disorder affecting multiple systems including the EYE, the NERVOUS SYSTEM, and the KIDNEY. Clinical features include congenital CATARACT; MENTAL RETARDATION; and renal tubular dysfunction (FANCONI SYNDROME; RENAL TUBULAR ACIDOSIS; X-LINKED HYPOPHOSPHATEMIA or vitamin-D-resistant rickets) and SCOLIOSIS. This condition is due to a deficiency of phosphatidylinositol 4,5-bisphosphate-5-phosphatase leading to defects in PHOSPHATIDYLINOSITOL metabolism and INOSITOL signaling pathway. (from Menkes, Textbook of Child Neurology, 5th ed, p60; Am J Hum Genet 1997 Jun;60(6):1384-8)


Cuneus Cortex
Occipital Lobe
Calcarine Fissure
Occipital Gyrus
Calcarine Sulcus
Gyrus Lingualis
Cuneus Gyrus
Medial Occipitotemporal Gyrus
Occipital Sulcus
Occipital Cortex
Sulcus Calcarinus
Lunate Sulcus
Cuneus
Occipital Region
Lingual Gyrus
Annectant Gyrus
Cuneate Lobule

Posterior portion of the CEREBRAL HEMISPHERES responsible for processing visual sensory information. It is located posterior to the parieto-occipital sulcus and extends to the preoccipital notch.


Group B Streptococcal Infections
Infections, Streptococcal
Group A Strep Infection
Group A Streptococcal Infection
Group A Streptococcal Infections
Group B Strep Infection
Group B Streptococcal Infection
Streptococcal Infections

Infections with bacteria of the genus STREPTOCOCCUS.


Synteny
Syntenic Conservation
Chromosomal Colinearity
Colinearity, Chromosomal
Syntenic Homology
Conserved Synteny

The similarity between chromosome segments or chromosomes in the linear arrangement of genes (GENE ORDER) or genetic markers.


Malignancy
Malignant Neoplasms
Benign Neoplasms
Neoplasia
Tumors
Cancer
Neoplasm
Neoplasms, Benign
Neoplasms

New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.


Tripelennamine Monohydrochloride
Tripelennamine
Histantin
Tripelennamine Maleate
Vetibenzamin
Tripelennamine Citrate
Tripelennamine Maleate (1:1)
Tripelennamine Citrate (1:1)
Pyribenzamine
Tripelennamine Hydrochloride
Azaron

A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat ASTHMA; HAY FEVER; URTICARIA; and RHINITIS; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.


LF-178
Livesan
durafenat
Fenofibrat Stada
Nu-Fenofibrate
Fenobeta
Lipantil
Phenofibrate
Liparison
Normalip
Secalip
Lipidil
Tricor
Antara Micronized Procetofen
fenofibrat von ct
Lipanthyl
Fenofibrat FPh
Fenofibrat AbZ
Procetofen
Lipidil-Ter
Fénofibrate Debat
MTW-Fenofibrat
Fenofanton
Fenofibrat Hexal
CiL
Supralip
Apo-Fenofibrate
Fenofibrat AZU
Apo-Feno-Micro
Fenofibrat AL
Novo-Fenofibrate
Controlip
PMS-Fenofibrate Micro
Fénofibrate MSD
Lofibra
Fenofibrate
Fenofibrat Heumann
Procetofene
Gen-Fenofibrate
Fenofibrat-ratiopharm

An antilipemic agent which reduces both CHOLESTEROL and TRIGLYCERIDES in the blood.


Resource-Based Relative Value Scale
Relative Value Scales
Relative-Value Schedules
Resource Based Relative Value Scale

Coded listings of physician or other professional services using units that indicate the relative value of the various services they perform. They take into account time, skill, and overhead cost required for each service, but generally do not consider the relative cost-effectiveness. Appropriate conversion factors can be used to translate the abstract units of the relative value scales into dollar fees for each service based on work expended, practice costs, and training costs.


Long-Term Effects
Effects, Long-Term
Time
Longterm Effects
Effects, Longterm

The dimension of the physical universe which, at a given place, orders the sequence of events. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)


ORC2 Protein
ORC5 Protein
ORC4 Protein
Origin Recognition Complex, Subunit 2
Origin Recognition Complex Proteins
Origin Recognition Complex
Origin Recognition Complex, Subunit 4
ORC1 Protein
ORC3 Protein
Origin Recognition Complex, Subunit 1
Origin Recognition Complex, Subunit 5
Origin Recognition Complex, Subunit 3
ORC6 Protein
Origin Recognition Complex, Subunit 6

The origin recognition complex is a multi-subunit DNA-binding protein that initiates DNA REPLICATION in eukaryotes.


Tonsillar Hernia
Bifid Cranium
Cranial Meningoencephalocele
Cranium Bifidum
Notoencephalocele
Hernia, Cerebral
Cephalocele
Acquired Encephalocele
Encephalocele, Acquired
Encephalocele, Occipital
Frontal Encephalocele
Craniocele
Cerebellar Hernia
Occipital Encephalocele
Tonsillar Herniation
Encephalocele, Frontal
Encephalocele, Sincipital
Encephalocele
Sincipital Encephalocele
Cerebellar Herniation

Brain tissue herniation through a congenital or acquired defect in the skull. The majority of congenital encephaloceles occur in the occipital or frontal regions. Clinical features include a protuberant mass that may be pulsatile. The quantity and location of protruding neural tissue determines the type and degree of neurologic deficit. Visual defects, psychomotor developmental delay, and persistent motor deficits frequently occur.


Hurthle Cell Tumor
Huerthle Cell Tumor
Adenoma, Oxyphilic
Oncocytoma

A subtype of follicular adenoma in the THYROID GLAND. The Hurthle cell tumor is composed predominantly (at least 75%) or entirely of oxyphil cells. Hurthle cell neoplasms can be divided into benign and malignant categories. Malignant Hurthle cell carcinoma usually appear in patients over 60 years of age and are radioresistant.


Oxytocics
Oxytocic Effect
Oxytocic Drugs
Oxytocic Agents
Oxytocic Effects
Uterine Stimulants

Drugs that stimulate contraction of the myometrium. They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (ABORTIFACIENTS). Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (From AMA Drug Evaluations, 1994, p1157)


Sodium Tyropanoate
Tyropanoate
WIN-88512
Bilopaque
Tyropanoate Sodium

A diagnostic aid as a radiopaque medium in cholecystography.


Laxettes Thalinol Ap-La-Day Ex-Lax Modane Laxatone Feen-A-Mint Phenolphthalein

An acid-base indicator which is colorless in acid solution, but turns pink to red as the solution becomes alkaline. It is used medicinally as a cathartic.


Dyskinesia, Medication-Induced
Dyskinesia, Drug-Induced
Medication-Induced Dyskinesia

Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)


Satellites, Artificial
Launch Vehicle
Biosatellites
Space Shuttle
Satellites, Man-Made
Spaceship
Space Ship
Space Craft
Spacecraft
Space Vehicles
Space Probe
Space Capsule

Devices, manned and unmanned, which are designed to be placed into an orbit about the Earth or into a trajectory to another celestial body. (NASA Thesaurus, 1988)


Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).


An antiarrhythmic agent which exerts a potential- and frequency-dependent block of SODIUM CHANNELS.


Receptors, Adrenergic, alpha-1
alpha-1D Adrenergic Receptor
alpha-1B Adrenergic Receptor
Adrenergic Receptor, alpha-1
Receptors, Adrenergic, alpha-1D
alpha-1A Adrenergic Receptor
Adrenergic alpha-1D Receptors
Receptors, Adrenergic, alpha-1A
Receptors, Adrenergic, alpha-1B
Receptor, Adrenergic, alpha-1D
Receptor, Adrenergic, alpha-1
alpha 1 Adrenergic Receptor
Adrenergic alpha-1A Receptors
Adrenergic alpha-1B Receptors
Receptors, alpha-1 Adrenergic
Receptor, Adrenergic, alpha-1A
Receptor, Adrenergic, alpha-1B
alpha-1C Adrenergic Receptor
Adrenergic alpha-1 Receptors
alpha-1 Adrenergic Receptors

A subclass of alpha-adrenergic receptors that mediate contraction of SMOOTH MUSCLE in a variety of tissues such as ARTERIOLES; VEINS; and the UTERUS. They are usually found on postsynaptic membranes and signal through GQ-G11 G-PROTEINS.


Purslane
Portulaca oleracae
Portulaca oleracea
Portulaca

A plant genus of the family PORTULACACEAE.


Peripheral Nervous System Drugs
Peripheral Nervous System Agents
Peripheral Nervous System Effect
Peripheral Nervous System Effects

Drugs that act principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. (From Smith and Reynard, Textbook of Pharmacology, 1991, p75)


Hospital Group Purchasing
Shared Purchasing
Joint Purchasing, Hospital
Group Purchasing, Hospital
Group Purchasing
Hospital Joint Purchasing
Joint Purchasing
Purchasing, Hospital, Group
Hospital Shared Purchasing
Purchasing, Hospital, Shared
Shared Purchasing, Hospital
Purchasing, Hospital, Joint

A shared service which combines the purchasing power of individual organizations or facilities in order to obtain lower prices for equipment and supplies. (From Health Care Terms, 2nd ed)


Dimethyldioxanedione Polymer with Dioxanedione Polymer

Dioxanedione Polymer with Dimethyldioxanedione Polymer

A polyester used for absorbable sutures & surgical mesh, especially in ophthalmic surgery. 2-Hydroxy-propanoic acid polymer with polymerized hydroxyacetic acid, which forms 3,6-dimethyl-1,4-dioxane-dione polymer with 1,4-dioxane-2,5-dione copolymer of molecular weight about 80,000 daltons.


Trans-Activation, Genetic
Induction, Genetic
Transcription Activation
Gene Activation
Transactivation
Transcriptional Activation
Genetic Induction

Increased rate of gene expression directed by TRANS-ACTIVATORS.


Mental Retardation, Unusual Facies, And Intrauterine Growth Retardation

A syndrome that is considered as part of the spectrum of Wolf-Hirschhorn Syndrome variability. It maps to the short arm of chromosome 4, at 4p16.


Collagen Type-VIII, alpha1 Chain
Collagen Type-VIII, alpha1 Subunit
Collagen Type VIII
Type VIII Collagen
Collagen alpha1(VIII)
Procollagen Type VIII
Type VIII Procollagen

A non-fibrillar collagen originally found in DESCEMET MEMBRANE. It is expressed in endothelial cell layers and in tissues undergoing active remodeling. It is heterotrimer comprised of alpha1(VIII) and alpha2(VIII) chains.


Pachyrhizus erosus
Jicama
Bean, Yam
Pachyrhizus
Pachyrhizus tuberosus

A plant genus of the family FABACEAE. Some Pachyrhizus have been reclassified to PUERARIA. Do not confuse with yam (IPOMOEA; or DIOSCOREA) or African yam bean (SPHENOSTYLIS).


c-crk-I Proto-Oncogene Protein
Proto-Oncogene Proteins c-crk
Proto-Oncogene Protein c-crk
CT10 Regulator of Kinase Protein
Proto-Oncogene Protein c-crk-2
c-CrkII Protein
CrkII Adapter Protein
CRKII Protein
c-crk-3 Proto-Oncogene Protein
Proto-Oncogene Protein c-crk-3
Crk-1 Protein
Proto-Oncogene Protein c-crk-1
CRKI Protein
c-crk Proto-Oncogene Proteins
c-crkI Protein
c-crk Protein
crk Proto-Oncogene Proteins
Crk-2 Protein
c-crk-2 Proto-Oncogene Protein
Crk3 Protein
c-CrkIII Protein
CrkIII Protein

Signal transducing adaptor proteins that contain SRC HOMOLOGY DOMAINS and play a role in CYTOSKELETON reorganization. c-crk protein is closely related to ONCOGENE PROTEIN V-CRK and includes several alternatively spliced isoforms.


Leukocyte Migration Capillary Tube Technique (LMCT)

Assays that measure the rate of migration of LEUKOCYTES. They may involve a variety of techniques such as measuring the movement of leukocytes through substrates such as AGAROSE gels or the rate of exit of cells from a glass capillary.


Benign and malignant tumors of the HYPOTHALAMUS. Pilocytic astrocytomas and hamartomas are relatively frequent histologic types. Neoplasms of the hypothalamus frequently originate from adjacent structures, including the OPTIC CHIASM, optic nerve (see OPTIC NERVE NEOPLASMS), and pituitary gland (see PITUITARY NEOPLASMS). Relatively frequent clinical manifestations include visual loss, developmental delay, macrocephaly, and precocious puberty. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2051)


c-rel Proto-Oncogenes
rel Oncogene
Genes, rel
v-rel Oncogenes
rel Genes
v-rel Genes
c-rel Genes

Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.


Infarction, Brain, Posterior Circulation

Anterior Cerebral Circulation Infarction

Infarction, Posterior Circulation, Brain

Infarction, Anterior Cerebral Circulation

Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.


Flatfishes
Scophthalmus maximus
Solea
Pleuronectiformes
Turbot
Psetta maxima

A genus of fish in the family Soleidae (soles).


Computer-Assisted Image Processing
Image Analysis, Computer-Assisted
Computer-Assisted Image Analysis
Analysis, Computer-Assisted Image
Image Reconstruction
Image Processing, Computer-Assisted

A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.


Mallotus Plant
Kamala Tree
Mallotus philippensis

A plant genus of the family EUPHORBIACEAE. Members contain fredelin type TRITERPENES, mallorepine (a cyano-pyridone), and hydrolyzable TANNINS.


T-Cell Prolymphocytic Leukemia
Leukemia, Lymphocytic, Chronic, T-Cell
Lymphocytic Leukemia, T Cell, Chronic
Leukemia, T Cell, Chronic
Leukemia, T-Cell, Chronic
T-Lymphocytic Leukemia, Chronic
T-Cell Leukemia, Chronic
Lymphocytic Leukemia, T-Cell, Chronic
Leukemia, Prolymphocytic, T-Cell
Leukemia, Lymphocytic, Chronic, T Cell

A lymphoid leukemia characterized by a profound LYMPHOCYTOSIS with or without LYMPHADENOPATHY, hepatosplenomegaly, frequently rapid progression, and short survival. It was formerly called T-cell chronic lymphocytic leukemia.


Ciliary Motility Disorders
Ciliary Dyskinesia, Primary
Immotile Cilia Syndrome
Primary Ciliary Dyskinesia
Ciliary Dyskinesia

Conditions caused by abnormal CILIA movement in the body, usually causing KARTAGENER SYNDROME, chronic respiratory disorders, chronic SINUSITIS, and chronic OTITIS. Abnormal ciliary beating is likely due to defects in any of the 200 plus ciliary proteins, such as missing motor enzyme DYNEIN arms.


Sleep-Related Abnormal Swallowing Syndrome

Movements or behaviors associated with sleep, sleep stages, or partial arousals from sleep that may impair sleep maintenance. Parasomnias are generally divided into four groups: arousal disorders, sleep-wake transition disorders, parasomnias of REM sleep, and nonspecific parasomnias. (From Thorpy, Sleep Disorders Medicine, 1994, p191)


Salsify, Yellow
Goat's Beard
Tragopogon porrifolius
Tragopogon pratensis
Salsify, Common
Tragopogon

A plant genus of the family ASTERACEAE. The root and shoots have been used for food.


Prednacinolone Desone Desonide Locapred Tridésonit Tridesilon Desocort Locatop Desowen

A nonfluorinated corticosteroid anti-inflammatory agent used topically for DERMATOSES.


Family Planning Personnel Characteristics

Persons trained to assist professional health personnel in communicating with residents in the community concerning needs and availability of health services.


Flavin Mononucleotide Monosodium Salt, Dihydrate

A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.


Betulaceae
Ostryopsis
Hop Hornbeam
Hornbeam
Carpinus
Ostrya
Hornbeam, Hop


Chaperonin Containing t-Complex Polypeptide

Chaperonin-Containing T-Complex Polypeptide 1

A group II chaperonin found in eukaryotic CYTOSOL. It is comprised of eight subunits with each subunit encoded by a separate gene. This chaperonin is named after one of its subunits which is a T-COMPLEX REGION-encoded polypeptide.


Endosomal Sorting Complex Required for Transport Machinery

Endosomal Sorting Complexes Required for Transport

Endosomal Sorting Complex Required for Transport III

A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.


Optimax
Ardeydorm
Trofan
Naturruhe
Lyphan
Tryptan
L-Tryptophan
Ardeytropin
PMS-Tryptophan
Tryptophan
Tryptacin
L-Tryptophan-ratiopharm
Levotryptophan
ratio-Tryptophan
Tryptophan Metabolism Alterations

An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.


p85(gag-mos)
mos Oncogene Proteins
p37(v-mos)
Oncogene Products v-mos
Oncogene Protein p37(v-mos)
p37 v-mos
Oncogene Proteins v-mos
Fusion Proteins, gag-mos
Oncogene Proteins mos
v-mos Proteins
Oncogene Protein p85(gag-mos)
p85 gag-mos

Transforming proteins coded by mos oncogenes. The v-mos proteins were originally isolated from the Moloney murine sarcoma virus (Mo-MSV).


Mirza
Microcebus
Lemur, Dwarf
Phaner
Cheirogaleus
Cheirogaleidae
Allocebus
Lemur, Mouse

A family of the order PRIMATES, suborder Strepsirhini (PROSIMII), containing five genera. All inhabitants of Madagascar, the genera are: Allocebus, Cheirogaleus (dwarf lemurs), Microcebus (mouse lemurs), Mirza, and Phaner.


Amnioscopic Surgery
Surgical Procedures, Amnioscopic
Embryoscopic Surgery
Embryoscopic Surgical Procedures
Surgery, Amnioscopic
Fetoscopy
Surgery, Fetoscopic
Surgery, Embryoscopic
Fetoscopic Surgery
Fetoscopic Surgical Procedures
Surgical Procedures, Fetoscopic
Amnioscopy
Surgical Procedures, Embryoscopic
Amnioscopic Surgical Procedures
Embryoscopy

Endoscopic examination, therapy or surgery of the fetus and amniotic cavity through abdominal or uterine entry.


Waterclover
Marsileaceae
Pepperwort
Marsilea
Clover, Water

A plant family of the order Hydropteridales, class Filicopsida, division PTERIDOPHYTA. They are aquatic ferns with quatrifoliate leaves resembling four leaf clover, creeping rhizome, and bean shaped sporocarps.


Movement, Cell
Motility, Cell
Migration, Cell
Locomotion, Cell
Cell Migration
Cell Movement

The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.


Kv1.1 Potassium Channel, Alpha Subunit
KCNA1 Potassium Channel
Kv1.1alpha
Kv1.1 Potassium Channel
Kv1.1 Potassium Channel, Beta Subunit
Kv1.1beta

A delayed rectifier subtype of shaker potassium channels that is commonly mutated in human episodic ATAXIA and MYOKYMIA.


Brominated analog of MANNITOL which is an antineoplastic agent appearing to act as an alkylating agent.


Trifluoperazine
Triftazin
Stelazine
Trifluperazine
Eskazine
Trifluoperazine Hydrochloride
Flupazine
Trifluoperazine HCL
Apo-Trifluoperazine
Terfluzine
Trifluoroperazine

A phenothiazine with actions similar to CHLORPROMAZINE. It is used as an antipsychotic and an antiemetic.


Muscles of Pharynx
Velopharyngeal Muscle
Stylopharyngeus
Palatopharyngeus
Salpingopharyngeus
Palatopharyngeal Muscle
Pharyngeal Muscles

The muscles of the PHARYNX are voluntary muscles arranged in two layers. The external circular layer consists of three constrictors (superior, middle, and inferior). The internal longitudinal layer consists of the palatopharyngeus, the salpingopharyngeus, and the stylopharyngeus. During swallowing, the outer layer constricts the pharyngeal wall and the inner layer elevates pharynx and LARYNX.


Choroid Plexus Neoplasms, Primary
Neoplasms, Choroid Plexus
Choroid Plexus Neoplasms
Choroid Plexus Tumors
Primary Choroid Plexus Neoplasms

Benign or malignant tumors which arise from the choroid plexus of the ventricles of the brain. Papillomas (see PAPILLOMA, CHOROID PLEXUS) and carcinomas are the most common histologic subtypes, and tend to seed throughout the ventricular and subarachnoid spaces. Clinical features include headaches, ataxia and alterations of consciousness, primarily resulting from associated HYDROCEPHALUS. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2072; J Neurosurg 1998 Mar;88(3):521-8)


Services, Food
Meal on Wheels
Meals on Wheels
Food Services

Functions, equipment, and facilities concerned with the preparation and distribution of ready-to-eat food.


Oxytetracycline, Disodium Salt, Dihydrate

Oxytetracycline, (4a beta,5 beta,5a beta,12a beta)-Isomer

A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES RIMOSUS and used in a wide variety of clinical conditions.


Brain Perivascular Spaces
Glymphatic System
Glymphatic Pathway
Meningeal Lymphatic Vessels
Glymphatic Clearance System
Virchow-Robin Spaces

A vascular waste clearance system in the brain analogous to the lymphatic system that facilitates transporting of solutes and waste products from CEREBROSPINAL FLUID (CSF) and brain INTERSTITIAL FLUID (ISF). CSF from the SUBARACHNOID SPACE enters the brain periarterial spaces, into the interstitium via channels (e.g., AQUAPORIN 4 PROTEIN) on astrocytic endfeet and exchanges with brain ISF before perivenous drainage of solutes and waste.


Amlodipine, (+-)-Isomer, Maleate (1:1)
Amlodipine Maleate (1:1)
Amlor
Amlodipine, (+-)-Isomer
Amlodipine Maleate
Amlodis
Amlodipine, (S)-Isomer, Maleate (1:1)
Astudal
Norvasc
Amlodipine, (R)-Isomer
Amlodipine
Amlodipine Besylate
Istin

A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.


Indirect Antiglobulin Test
Indirect Coombs Test
Antiglobulin Consumption Test
Direct Antiglobulin Test
Antihuman Globulin Consumption Test
Direct Coombs Test
Anti-Human Globulin Consumption Test
Coombs' Test
Coombs Test
Antiglobulin Test

A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.


Blood Physiological Phenomena
Blood Physiological Processes
Physiology, Blood
Blood Physiology
Blood Physiological Concepts
Blood Physiologic Processes
Blood Physiological Phenomenon

Physiological processes and properties of the BLOOD.


Inductively Coupled Plasma Atomic Emission Spectrophotometry

Inductively Coupled Plasma Atomic Emission Spectroscopy

Spectrophotometric techniques by which the absorption or emmision spectra of radiation from atoms are produced and analyzed.


Amitriptylin-Neuraxpharm
Endep
Tryptizol
Apo-Amitriptyline
Amitriptyline Hydrochloride
Amineurin
Amitriptylin RPh
Amitriptylin Desitin
Elavil
Amitrol
Damilen
Domical
Amitrip
Sarotex
Saroten
Laroxyl
Amitriptyline
Syneudon
Anapsique
Novoprotect
Triptafen
Lentizol
Amitriptylin Beta
Tryptine
Tryptanol

Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.


PMS-Fluorometholone
FML
Fluorometholone
FML Liquifilm
Fluor-Op
Flucon
Isopto Flucon
Efflumidex
Fluoro-Ophtal
Fluoropos
Cortisdin
FML Forte

A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)


Dasyprocta leporina
Brazilian Agoutis
Green Acouchi
Red Acouchi
Agoutis
Acouchis
Dasyproctidae
Myoprocta acouchy
Myoprocta
Myoprocta pratti
Dasyprocta


Sanorex Teronac Mazindole AN-448 Solucaps Teronak Mazanor Mazindol Diestet Sanjorex

Tricyclic anorexigenic agent unrelated to and less toxic than AMPHETAMINE, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter.


Ostrea
Oyster, True
Oysters, True
Ostrea edulis

A genus of oysters in the family OSTREIDAE, which includes the edible true oyster, Ostrea edulis.


Penicillin-Binding Proteins
Peptidoglycan Synthetase
Penicillin-Binding Protein 7
Penicillin-Binding Protein 6
Penicillin-Binding Protein 3
Penicillin-Binding Protein 5
Penicillin-Binding Protein 1A
Penicillin-Binding Protein-2a
Penicillin-Binding Protein 1b
Penicillin-Binding Protein
Penicillin-Binding Protein 1
Penicillin-Binding Protein 2b
Penicillin-Binding Protein 2
Penicillin-Binding Protein 4
Penicillin-Binding Protein 2a

A complex of enzymes that synthesize the peptidoglycan cell wall structure.


Briquet Syndrome
Pain Disorder
Somatoform Disorders
Medically Unexplained Syndrome
Medically Unexplained Syndromes
Somatization Disorder

Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by another medical condition, by the direct effects of a substance, or by another mental disorder. The MEDICALLY UNEXPLAINED SYMPTOMS must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. In contrast to FACTITIOUS DISORDERS and MALINGERING, the physical symptoms are not under voluntary control. (APA, DSM-V)


A pyrimidine and thiazole derived ANTINEOPLASTIC AGENT and PROTEIN KINASE INHIBITOR of BCR-ABL KINASE. It is used in the treatment of patients with CHRONIC MYELOID LEUKEMIA who are resistant or intolerant to IMATINIB.


A piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS.


Myrobalans
Arjuna Tree
Arjun Tree
Terminalia arjuna
Terminalia

A plant genus of the family COMBRETACEAE. Members contain arjunin, an ellagitannin (TANNINS).


Hydrallazin
Hydralazine mono-Hydrochloride
Hydrazinophthalazine
Hydralazine Hydrochloride
Apressoline
Nepresol
Apressin
Apresoline
Hydralazine

A direct-acting vasodilator that is used as an antihypertensive agent.


Spores, Fungal
Conidia
Fungal Spores
Conidium


p87 Subunit, Class Ib Phosphatidylinositol 3-Kinase

Class Ib Phosphatidylinositol 3-Kinase, p110gamma Subunit

Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide

p84 Subunit, Class Ib Phosphatidylinositol 3-Kinase

Class Ib Phosphatidylinositol 3-Kinase, p101 Subunit

Phosphoinositide-3-Kinase, Regulatory Subunit 5

p110gamma Subunit, Class Ib Phosphatidylinositol 3-Kinase

Class Ib Phosphatidylinositol 3-Kinase, p84 Subunit

Class Ib Phosphatidylinositol 3-Kinase, p87 Subunit

A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the association of a p110gamma catalytic subunit and one of the three regulatory subunits of 84, 87, and 101 kDa in size. This subclass of enzymes is a downstream target of G PROTEIN-COUPLED RECEPTORS.


Ochotona Lagomorphs Lagomorpha Leporidae Ochotonidae Pikas


Subtractive Hybridization
Subtractive Hybridization Techniques
Supression Subtractive Hybridization
Supressive Subtractive Hybridization

Methods of studying differential GENE EXPRESSION of especially low-abundance, tissue-specific gene transcripts.


Locus, araC Regulator
Genes, araC
araC Genes
Regulator Locus, araC
araC Regulator Locus

Regulatory genes which encode a cyclic AMP receptor protein required for L-arabinose utilization in E. coli. It is an example of positive control or regulation of gene expression in the bacterial operon.


Scientific Bias
Biases, Ecological
Statistical Bias
Experimental Bias
Bias, Ecological
Outcome Measurement Errors
Bias, Statistical
Truncation Bias
Ecological Fallacy
Biases
Bias, Aggregation
Bias, Systematic
Ecological Biases
Truncation Biases
Ecological Bias
Fallacy, Ecological
Bias, Epidemiologic
Ecological Fallacies
Aggregation Bias
Fallacies, Ecological
Bias
Epidemiologic Biases
Statistical Biases
Biases, Statistical
Systematic Bias

Any deviation of results or inferences from the truth, or processes leading to such deviation. Bias can result from several sources: one-sided or systematic variations in measurement from the true value (systematic error); flaws in study design; deviation of inferences, interpretations, or analyses based on flawed data or data collection; etc. There is no sense of prejudice or subjectivity implied in the assessment of bias under these conditions.


Muscular Dystrophy, Distal, Late-Onset, Autosomal Dominant

Myopathy, Distal, Early-Onset, Autosomal Dominant

A heterogeneous group of genetic disorders characterized by progressive MUSCULAR ATROPHY and MUSCLE WEAKNESS beginning in the hands, the legs, or the feet. Most are adult-onset autosomal dominant forms. Others are autosomal recessive.


Aorta, Thoracic
Aortic Arch
Thoracic Aorta
Arch of the Aorta
Aorta, Descending

The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.


Mesenchyme
Mesenchyma
Intermediate Mesoderm
Mesoderm
Paraxial Mesoderm
Dorsal Mesoderm
Lateral Plate Mesoderm

It lies next to the neural tube and will form SOMITES.


Oppenheim's Disease
Fasciculation-Cramp Syndrome, Benign
Neuromuscular Diseases
Oppenheim Disease
Cramp-Fasciculation Syndrome
Foley-Denny-Brown Syndrome
Amyotonia Congenita

A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.


Transcobalamins
Transcobalamin III
Haptocorrin
Transcobalamin II
Transcobalamin I
Vitamin B 12-Binding Proteins
Cobalamin-Binding Proteins
Vitamin B12-Binding Proteins
Transcobalamin (I)
R-Binder
Cobalophilin
Vitamin B 12 Binder
Holo-Transcobalamin II

A group of carrier proteins which bind with VITAMIN B12 in the BLOOD and aid in its transport. Transcobalamin I migrates electrophoretically as a beta-globulin, while transcobalamins II and III migrate as alpha-globulins.


Mechanoreceptor Cells
Receptors, Stretch
Stretch Receptors
Krause's End Bulbs
Ruffini's Corpuscles
Mechanoreceptors
Meissner's Corpuscle
Golgi Tendon Organs
Neurotendinous Spindles

Cells specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. Mechanoreceptor cells include the INNER EAR hair cells, which mediate hearing and balance, and the various somatosensory receptors, often with non-neural accessory structures.


Tranquillizing Agents
Tranquilizing Effect
Tranquillizing Drugs
Tranquilizing Agents
Tranquilizing Effects
Ataractics
Tranquilizing Drugs

A traditional grouping of drugs said to have a soothing or calming effect on mood, thought, or behavior. Included here are the ANTI-ANXIETY AGENTS (minor tranquilizers), ANTIMANIC AGENTS, and the ANTIPSYCHOTIC AGENTS (major tranquilizers). These drugs act by different mechanisms and are used for different therapeutic purposes.


CDC2+-CDC28-related Protein Kinase
CDC2-Related Kinases
CDC2-CDC28 Kinases
CDC2-Related Kinase
CDC28-Related Kinases

A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE, S CEREVISIAE and the CDC2 PROTEIN KINASE found in mammalian species.


Adenine Nucleotide Carrier (Mitochondrial)

A class of nucleotide translocases found abundantly in mitochondria that function as integral components of the inner mitochondrial membrane. They facilitate the exchange of ADP and ATP between the cytosol and the mitochondria, thereby linking the subcellular compartments of ATP production to those of ATP utilization.


Analysis, Statistical Factor
Factor Analysis
Statistical Factor Analysis
Analysis, Factor
Factor Analysis, Statistical

A set of statistical methods for analyzing the correlations among several variables in order to estimate the number of fundamental dimensions that underlie the observed data and to describe and measure those dimensions. It is used frequently in the development of scoring systems for rating scales and questionnaires.


Edible Coating
Edible Food Packaging Materials
Edible Packaging
Edible Films

Packaging materials that can be directly consumed. They provide barrier and protection, while enhancing quality and safety of food products. (Bourtoom, 2008).


G Protein-Coupled Inwardly-Rectifying Potassium Channel 4

G Protein-Coupled Inwardly-Rectifying Potassium Channel 1

G Protein-Coupled Inwardly-Rectifying Potassium Channels

G Protein-Coupled Inwardly-Rectifying Potassium Channel 2

G Protein-Coupled Inwardly-Rectifying Potassium Channel 3

A family of inwardly-rectifying potassium channels that are activated by PERTUSSIS TOXIN sensitive G-PROTEIN-COUPLED RECEPTORS. GIRK potassium channels are primarily activated by the complex of GTP-BINDING PROTEIN BETA SUBUNITS and GTP-BINDING PROTEIN GAMMA SUBUNITS.


Woolens
Wool Fiber
Wool Textiles
Wool Fabric
Woolen Fiber

Filament, thread, or yarn produced from WOOL.


Anaesthesin
Anesthesin
Benzocaine Acetate
Ethyl Aminobenzoate
Benzocaine Formate
Benzocaine Hydrochloride
4-Aminobenzoic Acid Ethyl Ester
Benzocaine Methanesulfonate
Bensokain
Benzocaine
Benzocaine Hydrobromide
Americaine
Ethoform

A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS.


A synthetic hormone used for androgen replacement therapy and as an hormonal antineoplastic agent (ANTINEOPLASTIC AGENTS, HORMONAL).


FOIA Requests
Public Access to Information
Access to Information
Open Access to Information
Freedom of Information Act Requests

The Freedom of Information Act, passed in 1966, provides the public and industry a means of acquiring information about Federal Government activities.


3 alpha-Hydroxysteroid Dehydrogenase (B-Specific)

NADPH-5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase

5 alpha-3 alpha-Hydroxysteroid Dehydrogenase

A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.


Natto Bacteria
Bacillus subtilis var. natto
Bacillus subtilis (natto)
Bacillus subtilis

The source of nattokinase and used for fermenting SOYBEANS to NATTO.


Polymerase Chain Reaction
Inverse PCR
Inverse Polymerase Chain Reaction
Anchored PCR
Nested Polymerase Chain Reaction
Nested PCR
PCR
Anchored Polymerase Chain Reaction

In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.


Selenium Oxides
Selenium Oxide
Selenium Trioxide
Selenium Dioxide
Selenium Monoxide

Inorganic compounds formed through the oxidation of selenium.


Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.


Black Cohosh
Bugbane, Black
Cimicifuga racemosa
Cimicifuga
Cohosh, Black
Actaea racemosa

A plant genus of the family RANUNCULACEAE that contains triterpenoid saponins. Remifemin from C. racemosa is used to suppress LUTEINIZING HORMONE. It is reclassified by some to ACTAEA. The common name of black snakeroot is also used with ASARUM and SANICULA.


Immersion Feet
Trench Feet
Trench Foot
Immersion Foot

A condition of the feet produced by prolonged exposure of the feet to water. Exposure for 48 hours or more to warm water causes tropical immersion foot or warm-water immersion foot common in Vietnam where troops were exposed to prolonged or repeated wading in paddy fields or streams. Trench foot results from prolonged exposure to cold, without actual freezing. It was common in trench warfare during World War I, when soldiers stood, sometimes for hours, in trenches with a few inches of cold water in them. (Andrews' Diseases of the Skin, 8th ed, p27)


SRY (Sex Determining Region Y)-Box 1 Transcription Factor

SRY (Sex Determining Region Y)-Box 3 Transcription Factor

A subclass of SOX transcription factors that are expressed in neuronal tissue where they may play a role in the regulation of CELL DIFFERENTIATION. Members of this subclass are generally considered to be transcriptional activators.


Filamin 1
Filamin C
280 kDa Actin-Binding Protein
Filamin A
Filamin B
Merofilamins
beta-Filamin
Filamin 1-Like Protein
alpha-Filamin
Filamin
Filamins

A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences.


A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)


Adeno-Associated Viruses
Dependovirus
Virus, Adeno-Associated
Adeno-Associated Virus
Viruses, Adeno-Associated

A genus of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, which are dependent on a coinfection with helper adenoviruses or herpesviruses for their efficient replication. The type species is Adeno-associated virus 2.


Swine
Warthogs
Phacochoerus
Pigs
Suidae
Wart Hogs

Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).


Headache Disorders, Secondary
Analgesic Overuse Headache
Analgesic Rebound Headache
Medication Overuse Headache
Secondary Headache Disorders

Conditions with HEADACHE symptom that can be attributed to a variety of causes including BRAIN VASCULAR DISORDERS; WOUNDS AND INJURIES; INFECTION; drug use or its withdrawal.


Haw River Syndrome
Naito-Oyanagi Disease
Progressive Myoclonic Epilepsy
Myoclonic Epilepsies, Progressive
Progressive Myoclonus Epilepsies
Biotin-Responsive Encephalopathy
Familial Progressive Myoclonic Epilepsy
Myoclonic Epilepsy, Progressive
Dentatorubral-Pallidoluysian Atrophy
May-White Syndrome
Myoclonus-Nephropathy Syndrome
Atypical Inclusion-Body Disease
Ataxia, Chorea, Seizures, And Dementia
Action Myoclonus-Renal Failure Syndrome
Naito Oyanagi Disease

A heterogeneous group of primarily familial EPILEPSY disorders characterized by myoclonic seizures, tonic-clonic seizures, ataxia, progressive intellectual deterioration, and neuronal degeneration. These include LAFORA DISEASE; MERRF SYNDROME; NEURONAL CEROID-LIPOFUSCINOSIS; sialidosis (see MUCOLIPIDOSES), and UNVERRICHT-LUNDBORG SYNDROME.


Propilin
Pilin Precursors
Sex Pili Structural Proteins
Pre-Pilin
Fimbriae Protein Precusors
Pili Structural Proteins
Pilin
Pilins
Fimbriae Proteins

Proteins that are structural components of bacterial fimbriae (FIMBRIAE, BACTERIAL) or sex pili (PILI, SEX).


Chamaecyparis nootkatensis
Cypress, Lawson's False
Lawson's False Cypress
Chamaecyparis lawsoniana
Chamaecyparis
Cedar, Yellow
Atlantic White Cedar
Hinoki Cypress
Chamaecyparis thyoides
Chamaecyparis obtusa
Cedar, Atlantic White
Cypress, Yellow

A plant genus of the family CUPRESSACEAE which should not be confused with other cedar and cypress trees of THUJA or CUPRESSUS genera.


Pseudotumor, Inflammatory
Inflammatory Pseudotumor
Granuloma, Plasma Cell
Plasma Cell Granuloma

A slow-growing benign pseudotumor in which plasma cells greatly outnumber the inflammatory cells.


General Practitioner Assessment of Cognition

Neurobehavioral Cognitive Status Examination

Cognitive Assessment Screening Instrument

Unified Parkinson's Disease Rating Scale

Tests designed to assess various aspects of neurocognitive function or dementia.


Nu-Diflunisal Novo-Diflunisal Apo-Diflunisal Dolobis Dolobid MK-647 Dolocid Diflunisal

A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.


Periods, Neurologic Refractory
Period, Neurologic Refractory
Vvedenskii Inhibition
Neurologic Refractory Periods
Refractory Period, Neurologic
Inhibition, Vvedenskii
Neurologic Refractory Period
Refractory Period, Electrophysiological
Refractory Periods, Neurologic
Neuromuscular Transmission Fade
Refractory Period, Neurological
Inhibition, Wedensky
Tetanic Fade
Wedensky Inhibition
Neuromuscular Fade

A continuous refractory state preventing repolarization that occurs when the nerve is being stimulated with high electrical frequencies and ends when the application of current stops.


Hormone Replacement Therapy, Post-Menopausal

Postmenopausal Hormone Replacement Therapy

The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.


Timeout, Healthcare
Surgical Timeout
Surgical Time Out
Time Out, Healthcare

A period of time away from normal workflow taken to ensure key procedural details have been reviewed for better PATIENT SAFETY and help prevent MEDICAL ERRORS.


Carbonic Anhydrase I
Carbonic Anhydrase Isoenzyme B
Carbonic Anhydrase I Hiroshima-1
Carbonic Anhydrase B
CA I Hiroshima-1

A variant form of carbonic anhydrase I that has asparagine at position 86 replaced by glycine.


A synthetic non-aromatizable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.


Feeder Cell Layers
Feeder Layer
Feeder Layer Cell
Feeder Layer Cells
Feeder Cell
Feeder Cells
Feeder Layers

Cells used in COCULTURE TECHNIQUES which support the growth of the other cells in the culture. Feeder cells provide auxillary substances including attachment substrates, nutrients, or other factors that are needed for growth in culture.


Embryonic Pattern Formation
Body Pattern Formation
Body Patterning
Polarity of Development
Axial Patterning (Embryology)
Body Pattern Specification
Embryonic Pattern Specification

The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.


Equipment, Hospital
Hospital Equipment and Supplies
Equipment and Supplies, Hospital
Hospital Supplies
Hospital Equipment
Supply, Hospital
Supplies, Hospital

Any materials used in providing care specifically in the hospital.


Hearing Loss, Transitory
Transitory Hearing Loss
Deafness, Transitory
Hearing Impairment
Hearing Loss
Hypoacusis

A general term for the complete or partial loss of the ability to hear from one or both ears.


Glial Cell Line-Derived Neurotrophic Factor Receptors

Glial Derived Neurotrophic Factor Receptor 3

Glial Derived Neurotrophic Factor Receptor 2

Glial Derived Neurotrophic Factor Receptor 4

Glial Derived Neurotrophic Factor Receptor 1

A family of GLYCOSYLPHOSPHATIDYLINOSITOL-anchored cell surface receptors that are specific for GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS. They form a multi-component receptor complex with PROTO-ONCOGENE PROTEIN C-RET and regulate a variety of intracellular SIGNAL TRANSDUCTION PATHWAYS in conjunction with c-ret protein.


Isoprinosine
NPT-10381
Imunovir
Methysoprinol
Metisoprinol
Isoprinosin
Inosiplex
Methisoprinol
Inosine Pranobex

An alkylamino-alcohol complex of inosine used in the treatment of a variety of viral infections. Unlike other antiviral agents, it acts by modifying or stimulating cell-mediated immune processes rather than acting on the virus directly.


Procedures with continuous blood purification (e.g., dialysis, filtration or perfusion) via vascular access designed to mimic kidney function in kidney diseases (e.g., ACUTE RENAL FAILURE and poisoning).


Bloodless Medical and Surgical Procedures

Medical, pre-operative, and post-operative organizational approaches that support patients who refuse allogeneic BLOOD TRANSFUSIONS or blood products for personal reasons, religious beliefs, or fear of bloodborne infections. Preparations for AUTOLOGOUS BLOOD TRANSFUSIONS may be a component of some programs.


Malnutrition, Fetal
Fetal Malnutrition
Fetal Nutrition Disorders
Nutrition Disorders, Fetal

Disorders caused by nutritional imbalance, either overnutrition or undernutrition, in the FETUS in utero.


Concretions of swallowed hair, fruit or vegetable fibers, or similar substances found in the alimentary canal.


Intravenous Infusions
Drip Infusions
Intravenous Drip
Infusions, Intravenous

The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.


Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.


Novel Erythropoiesis Stimulating Protein

A recombinant protein which stimulates ERYTHROPOIESIS used to treat ANEMIA.


Classical Lissencephalies and Subcortical Band Heterotopias

Disorders comprising a spectrum of brain malformations representing the paradigm of a diffuse neuronal migration disorder. They result in cognitive impairment; SEIZURES; and HYPOTONIA or spasticity. Mutations of two genes, LIS1, the gene for the non-catalytic subunit of PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB; and DCX or XLIS, the gene for doublecortin, have been identified as the most common causes of disorders in this spectrum. Additional variants of classical (Type I) lissencephaly have been linked to RELN, the gene for reelin, and ARX, the gene for aristaless related homeobox protein. (From Leventer, R.J., et al, Mol Med Today. 2000 Jul;6(7):277-84 and Barkovich, A.J., et al, Neurology. 2005 Dec 27;65(12):1873-87.)


True Lemurs
Prohapalemur
Sportive Lemurs
Eulemur
Bamboo Lemurs
Hapalemur
Ruffed Lemurs
Varecia
Lemuridae
Prolemur

A family of the order PRIMATES, suborder STREPSIRHINI, containing four genera which inhabit Madagascar and the Comoro Island. Most of the lemurs prefer wooded areas. The four genera are Hapalemur, LEMUR, Lepilemur, and Varecia.


Immunoblotting, Dot
Immunoblotting
Electroimmunoblotting
Immunoelectroblotting
Dot Immunoblotting
Immunoblotting, Reverse
Reverse Immunoblotting

Immunologic method used for detecting or quantifying immunoreactive substances. The substance is identified by first immobilizing it by blotting onto a membrane and then tagging it with labeled antibodies.


Analysis, RNA Sequence
RNA Sequence Analysis
Sequence Analysis, RNA
Determination, RNA Sequence
Sequence Determination, RNA
Determinations, RNA Sequence
RNA Sequence Determination
RNA Sequence Determinations
RNA Sequencing
Sequence Determinations, RNA

A multistage process that includes cloning, physical mapping, subcloning, sequencing, and information analysis of an RNA SEQUENCE.


Mice, Obese
Hyperglycemic Mice
Obese Mice
Mouse, Obese
Mouse, Hyperglycemic

Mutant mice exhibiting a marked obesity coupled with overeating, hyperglycemia, hyperinsulinemia, marked insulin resistance, and infertility when in a homozygous state. They may be inbred or hybrid.


Cancer of the Duodenum
Duodenal Neoplasms
Duodenal Cancer
Cancer of Duodenum


Isoquinoline and quinuclidine derivative that acts as a 5-HT3 RECEPTOR antagonist. It is used in the prevention of nausea and vomiting induced by cytotoxic chemotherapy, and for the prevention of post-operative nausea and vomiting.


LTE4
Leukotriene E4
Leukotrienes E
Leukotriene E-4
Leukotriene E

A biologically active principle of SRS-A that is formed from LEUKOTRIENE D4 via a peptidase reaction that removes the glycine residue. The biological actions of LTE4 are similar to LTC4 and LTD4. (From Dictionary of Prostaglandins and Related Compounds, 1990)


Type IIN von Willebrand Disease
von Willebrand Disease, Type 2B
Type 2A von Willebrand Disease
Type IIA von Willebrand Disease
Type 2B von Willebrand Disease
von Willebrand Disease, Type IIA
von Willebrand Disease, Type 2M
Type 2 von Willebrand Disease
von Willebrand Disease, Type IIM
von Willebrand Disease, Type IIB
von Willebrand Disease, Type IIN
Type 2N von Willebrand Disease
Type IIM von Willebrand Disease
von Willebrand Disease, Type II
von Willebrand Disease, Type 2A
von Willebrand Disease, Type 2N
Type 2M von Willebrand Disease
Type II von Willebrand Disease
Type IIB von Willebrand Disease
von Willebrand Disease, Type 2

A subtype of von Willebrand disease that results from qualitative deficiencies of VON WILLEBRAND FACTOR. The subtype is divided into several variants with each variant having a distinctive pattern of PLATELET-interaction.


A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.


Argingipain
Lysine Gingipain
RGP-2 Gingipain
Gingipain R
Arg-Gingipain
Gingipains
Gingipain R1
Lys-Gingipain
KGP Protease
Gingipain Cysteine Endopeptidases
RGPB Protein
Gingipain Proteases
Gingipain R2
Arginine Gingipain
Gingipain K

Cysteine endoproteinases, from periodontal pathogen PORPHYROMONAS GINGIVALIS, acting as virulence factors associated with PERIODONTITIS. They are produced as pre-proproteins which mature into ARGININE and LYSINE specific endopeptidases.


Lead Induced Nervous System Diseases, Adult

Nervous System Diseases, Lead Induced, Adult

Neurologic conditions in adults associated with acute or chronic exposure to lead or any of its salts. The most common lead related neurologic syndrome in adults consists of a polyneuropathy involving motor fibers. This tends to affect distal nerves and may present as wrist drop due to RADIAL NEUROPATHY. Additional features of chronic lead exposure include ANEMIA; CONSTIPATION; colicky abdominal pain; a bluish lead line of the gums; interstitial nephritis (NEPHRITIS, INTERSTITIAL); and saturnine gout. An encephalopathy may rarely occur. (From Adams et al., Principles of Neurology, 6th ed, p1212)


Engineering, Biomedical
Engineering, Clinical
Clinical Engineering
Biomedical Engineering

Application of principles and practices of engineering science to biomedical research and health care.


Vitamin D 2
Calciferols
Ergocalciferol
Vitamin D2
Ergocalciferols

Derivatives of ERGOSTEROL formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. They differ from CHOLECALCIFEROL in having a double bond between C22 and C23 and a methyl group at C24.


Encephalopathy, Subacute Necrotizing, Infantile

Subacute Necrotizing Encephalopathy, Juvenile

Subacute Necrotizing Encephalopathy, Infantile

Juvenile Subacute Necrotizing Encephalopathy

Subacute Necrotizing Encephalomyelitis, Infantile

Infantile Subacute Necrotizing Encephalopathy

Encephalopathy, Subacute Necrotizing, Juvenile

A group of metabolic disorders primarily of infancy characterized by the subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision loss, eye movement abnormalities, seizures, dysphagia, and lactic acidosis. Pathological features include spongy degeneration of the neuropile of the basal ganglia, thalamus, brain stem, and spinal cord. Patterns of inheritance include X-linked recessive, autosomal recessive, and mitochondrial. Leigh disease has been associated with mutations in genes for the PYRUVATE DEHYDROGENASE COMPLEX; CYTOCHROME-C OXIDASE; ATP synthase subunit 6; and subunits of mitochondrial complex I. (From Menkes, Textbook of Child Neurology, 5th ed, p850).


A plant genus of the family FABACEAE known for the edible beans.


Nuclear Factor I-C
TGGCA-Binding Protein
Nuclear Factor-1
NFI Transcription Factors
Nuclear Factor I-X
Nuclear Factor I-A
Nuclear Factor I-B
CAAT Box Transcription Factor
Nuclear Factor I

Transcription factors that were originally identified as site-specific DNA-binding proteins essential for DNA REPLICATION by ADENOVIRUSES. They play important roles in MAMMARY GLAND function and development.


Glutathione Organic Nitrate Ester Reductase

A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.


Cytokeratin
Keratins
Keratin-Associated Proteins
Keratin
Glycosylated Keratin
Keratin, Glycosylated
alpha-Keratin

A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.


Receptors, Corticoid Type I
Corticoid Type I Receptors
Corticoid I Receptor
Receptors, Mineralocorticoid
Receptors, Mineralocorticoids
Receptors, Corticoid I
Receptors, Aldosterone
Aldosterone Receptors
Mineralocorticoid Receptors
Aldosterone Receptor
Mineralocorticoid Receptor

Cytoplasmic proteins that specifically bind aldosterone and mediate its cellular effects. The aldosterone-bound receptor acts in the nucleus to regulate the transcription of specific segments of DNA.


Illicit use of chemicals and products whose vapors can be inhaled to produce a rapid mind-altering effect. Inhalants include aerosols, gases, and volatile solvents that are often inhaled repeatedly to achieve the short-lived intoxicating effect.


Sheep
Ovis
Dall Sheep
Ovis dalli
Sheep, Dall

Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.


Stretch-Shortening Exercise
Plyometric Exercise
Plyometric Drill
Stretch-Shortening Cycle Exercise
Stretch-Shortening Drill
Plyometric Training

Exercises in which muscles are repeatedly and rapidly stretched, followed by shortening, concentric MUSCLE CONTRACTION (e.g. jumping and rebounding). They are designed to exert maximal force in minimal time by increasing STRETCH REFLEX.


Cerebrovascular Accident, Acute
Cerebrovascular Accident
Stroke, Acute
Stroke
Apoplexy
Cerebral Stroke
Cerebrovascular Stroke
Cerebrovascular Apoplexy
Vascular Accident, Brain
CVA (Cerebrovascular Accident)

A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)


Archipallium
Paleocortex
Periallocortex
Insula of Reil
Allocortex
Cortical Plate
Cerebral Cortex
Insular Cortex
Cortex Cerebri

Type of cerebral cortex which does not pass through a perinatal phase of six-layered structure as in the NEOCORTEX and develops into three or four layers in the mature brain. Allocortex has three subareas: archi- paleo- and periallo-cortex.


Pituitary Adenylate Cyclase Activating Polypeptide 38

Pituitary Adenylate Cyclase Activating Polypeptide 27

Pituitary Adenylate Cyclase-Activating Polypeptide

A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.


Adrenocortical Adenoma
Adenoma, Adrenal Cortical
Conn Disease
Conn Adenoma
Adenoma, Adrenocortical
Conn's Disease

An ADENOMA of the ZONA GLOMERULOSA that produces ALDOSTERONE and HYPERALDOSTERONISM.


CNS Cysts
Central Nervous System Cysts
Cysts, Central Nervous System
Suprasellar Cyst
Rathke's Cleft Cysts
Rathke Cleft Cysts

Congenital or acquired cysts of the brain, spinal cord, or meninges which may remain stable in size or undergo progressive enlargement.


Kabi-2165
Fragmin
FR-860
Fragmine
Dalteparin
Dalteparin Sodium
Tedelparin

A low-molecular-weight fragment of heparin, prepared by nitrous acid depolymerization of porcine mucosal heparin. The mean molecular weight is 4000-6000 daltons. It is used therapeutically as an antithrombotic agent. (From Merck Index, 11th ed)


Rohipnol
Fluridrazepam
Fluninoc
Flunitrazepam-Neuraxpharm
Flunizep Von Ct
Narcozep
Flunimerck
Flunibeta
Fluni 1A Pharma
Flunitrazepam
RO-5-4200
Flunitrazepam-Ratiopharm
Rohypnol
Flunitrazepam-Teva

A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.


Sumac, China
Ailanthus altissima
Tree Of Heaven
China-Sumac
Ailanthus

A plant genus of the family SIMAROUBACEAE. Members contain ailantinols and other quassinoids.


Citrus
Pummelo Tree
Orange Tree, Bitter
Citrus grandis
Citron Tree
Citrus hystrix
Citrus Fruit
Lemon Tree
Orange Tree, Sour
Citrus bergamia
Kaffir Lime
Citrus reticulata
Orange Tree, Mandarin
Citrus limon
Fruit, Citrus
Orange Tree, Seville
Citrus maxima
Pomelo Tree
Citrus aurantium
Citrus medica
Tangerine Tree

A species of CITRUS that is much used as a tough rootstock for other CITRUS species. The fruit inhibits CYTOCHROME P-450 isoform 3A4 much like grapefruit (CITRUS PARADISI).


Motor Vehicles, Off-Road
Dirt-Bikes
Snowmobiles
Off-Road Motor Vehicles
Motorbikes
Minibikes
Three-Wheeled Vehicles
All-Terrain Vehicles
Three-Wheeler Vehicles

Motorized, recreational vehicles used on non-public roads. They include all-terrain vehicles, dirt-bikes, minibikes, motorbikes, trailbikes, and snowmobiles. Excludes MOTORCYCLES, which are considered public road vehicles.


Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated

Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration

Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)


Dependence, Opioid
Addiction, Opioid
Opiate Abuse
Opioid Dependence
Opioid Addiction
Opiate Dependence
Opioid-Related Disorders
Opioid Abuse
Opiate Addiction

Disorders related to or resulting from abuse or misuse of OPIOIDS.


Tigazon
Tigason
Ethyl Etrinoate
Ro-10-9359
Etretinate
Ro 10-9359
B10-9359

An oral retinoid used in the treatment of keratotic genodermatosis, lichen planus, and psoriasis. Beneficial effects have also been claimed in the prophylaxis of epithelial neoplasia. The compound may be teratogenic.


Ambulatory 24-hour Esophageal pH Monitoring

Analysis of the HYDROGEN ION CONCENTRATION in the lumen of the ESOPHAGUS. It is used to record the pattern, frequency, and duration of GASTROESOPHAGEAL REFLUX.


M-Band Proteins
M-Protein (muscle)
Connectin
alpha-Connectin
beta-Connectin
Titin 2
Titin 1
Myomesin
Skelemins
M-Line 185 kDa Protein
Titin Kinase
Muscle M-Line Protein
Titin

A giant elastic protein of molecular mass ranging from 2,993 kDa (cardiac), 3,300 kDa (psoas), to 3,700 kDa (soleus) having a kinase domain. The amino- terminal is involved in a Z line binding, and the carboxy-terminal region is bound to the myosin filament with an overlap between the counter-connectin filaments at the M line.


Phenoxybenzamine
Phenoxybenzamine Hydrochloride
Dibenzyline
Dibenylene
Dibenzylin
Dibenyline
Dibenzyran
Dibenziran

An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.


Fontan Circuit
Fontan Operation
Stage III Norwood Procedure
Norwood Procedure, Stage 2
Norwood Procedure, Stage III
Bidirectional Glenn Shunt
Norwood Procedure, Stage 3
Fontan Circulation
Stage 2 Norwood Procedure
Stage 3 Norwood Procedure
Fontan Palliation
Bidirectional Cavopulmonary Shunt
Bidirectional Glenn Procedure
Norwood Procedure, Stage II
Stage II Norwood Procedure
Hemi-Fontan Procedure
Fontan Procedure

A procedure in which total right atrial or total caval blood flow is channeled directly into the pulmonary artery or into a small right ventricle that serves only as a conduit. The principal congenital malformations for which this operation is useful are TRICUSPID ATRESIA and single ventricle with pulmonary stenosis.


Pneumonia, Radiation
Radiation Fibrosis
Fibrosis, Radiation
Pneumonitis, Radiation
Radiation Pneumonia
Radiation Pneumonitis

Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.


Encainide, (+)-Isomer
MJ-9067
Enkaid
Encainide Hydrochloride
Encainide
Encainide, (-)-Isomer
Encainide Hydrochloride, (+-)-Isomer

One of the ANTI-ARRHYTHMIA AGENTS, it blocks VOLTAGE-GATED SODIUM CHANNELS and slows conduction within the His-Purkinje system and MYOCARDIUM.


A dopamine D2 antagonist that is used as an antiemetic.


Tissue Kallikrein
Glandular Kallikrein-1
Tissue Kallikreins
Kallikrein 2
Glandular Kallikrein
Human Glandular Kallikrein 2
Human Glandular Kallikrein 1
Pancreatic Kallikrein
hK1 Kallikrein
Kallikrein 1
hK2 Kallikrein
Prostate Specific Kallikrein
Human Glandular Kallikreins
Urinary Kallikrein

A family of trypsin-like SERINE ENDOPEPTIDASES that are expressed in a variety of cell types including human prostate epithelial cells. They are formed from tissue prokallikrein by action with TRYPSIN. They are highly similar to PROSTATE-SPECIFIC ANTIGEN.


Natives
Population Groups
Tribes
Native-Born
Indigenous Population

Individuals classified according to their sex, racial origin, religion, common place of living, financial or social status, or some other cultural or behavioral attribute. (UMLS, 2003)


Heritable Pulmonary Arterial Hypertension

Idiopathic Pulmonary Arterial Hypertension

Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia

Pulmonary Hypertension, Primary, Dexfenfluramine-Associated

Pulmonary Hypertension, Primary, Fenfluramine-Associated

Familial or idiopathic hypertension in the PULMONARY CIRCULATION which is not secondary to other disease.


Transcription Factor AP-2 epsilon Protein

A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.


Lutein Cells
Granulosa-Lutein Cells
Theca-Luteal cells
Theca-Lutein Cells
Luteal Cells
Small Luteal Cells
Large Luteal Cells
Granulosa-Luteal Cells

PROGESTERONE-producing cells in the CORPUS LUTEUM. The large luteal cells derive from the GRANULOSA CELLS. The small luteal cells derive from the THECA CELLS.


An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.


Macaca mulatta
Rhesus Macaque
Chinese Rhesus Macaques
Monkey, Rhesus
Macaca mulatta lasiota
Rhesus Monkey

A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans.


Invasive Hyalohyphomycosis
Disseminated Hyalohyphomycosis
Pulmonary Hyalohyphomycosis
Cutaneous Hyalohyphomycosis
Splenic Hyalohyphomycosis
Subcutaneous Hyalohyphomycosis
Hyalohyphomycosis

OPPORTUNISTIC INFECTIONS caused by a heterogeneous group of MITOSPORIC FUNGI with clear (hyalo-) HYPHAE in the host. Common causative agents include ACREMONIUM; ASPERGILLUS; CHRYSOSPORIUM; FUSARIUM; PAECILOMYCES; PENICILLIUM; PSEUDALLESCHERIA; SCEDOSPORIUM; and SCOPULARIOPSIS. Normally a dermatomycoses, it can become invasive in the IMMUNOCOMPROMISED HOST.


Morse Taper Dental Implant-Abutment Interface

Morse Taper Dental Implant-Abutment Connection

Implant-abutment interface that uses two matching uniformly tapered (Morse taper) components to provide the interface. It creates a lock fit that aims to add stability and DENTAL LEAKAGE reduction.


Butanedioic Acid, 2,3-Dimercapto-, (R*,S*)-Isomer

Succimer Antimony Sodium Salt, (R*,S*)-Isomer

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.


SKF-75073-2
Cefonicid Monosodium
Sodium Cefonicid
Cefonicid Disodium Salt
Monocid
Cefonicid Monosodium Salt
Cefonicid
SK&F-75073

A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.


Carcinoma in Situ
Intraepithelial Neoplasms
Neoplasms, Intraepithelial
Carcinoma, Preinvasive
Carcinoma, Intraepithelial

A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.


A plant genus of the family ZINGIBERACEAE. Members contain galangin, yakuchinone-A, and diarylheptanoids.


Trace Minerals
Biometals
Trace Mineral
Trace Elements
Trace Element
Biometal

A group of chemical elements that are needed in minute quantities for the proper growth, development, and physiology of an organism. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


Breakpoint Determination, Antimicrobial Susceptibility

Antibacterial Susceptibility Breakpoint Determination

Breakpoint Determination, Antibacterial Susceptibility

Antimicrobial Susceptibility Breakpoint Determination

Pie chart displaying the sensitivity of a set of microbes to one agent or condition.


Renal Neoplasms
Cancer of the Kidney
Kidney Cancer
Neoplasms, Kidney
Renal Cancer
Kidney Neoplasms
Cancer of Kidney


A plant genus of the family APOCYNACEAE. It is a very poisonous plant that contains cardioactive agents.


Motilium
Domperidone
Domperidon Hexal
Ratio-Domperidone
Domperidon-TEVA
Domperidone Maleate (1:1)
Domperidon Stada
Nu-Domperidone
Nauzelin
Domidon
Domperidona Gamir
R-33,812
R-33812
Domperidon AL
Domperidone Maleate
Domperidone Monohydrochloride
Apo-Domperidone
Domperidon
Gastrocure
Novo-Domperidone
PMS-Domperidone
Péridys

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.


bcl2-Associated X Protein Isoform sigma
bcl-2-Associated X Protein
Bax-alpha Protein
Bax Protein
bcl2-Associated X Protein Isoform omega
bcl2-Associated X Protein Isoform alpha
Bax-sigma Protein
Bax-delta Protein
Bax-omega Protein
Bax Apoptosis Regulator Protein
Bax-beta Protein
bcl2-Associated X Protein Isoform beta
bcl2-Associated X Protein
bcl2-Associated X Protein Isoform delta

A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.


Blastocyst Disintegration
Disintegration of Blastocyst
Embryo Disintegration
Embryo Loss
Disintegration of Embryo
Embryo Resorption
Embryo Death

Early pregnancy loss during the EMBRYO, MAMMALIAN stage of development. In the human, this period comprises the second through eighth week after fertilization.


Glycoprotein Ib, Platelet, Deficiency Of

Von Willebrand Factor Receptor Deficiency

A familial coagulation disorder characterized by a prolonged bleeding time, unusually large platelets, and impaired prothrombin consumption.


Infectious Disease Contact Tracing
Communicable Disease Contact Tracing
Partner Notification
Contact Tracing
Notification, Partner

Identification of those persons (or animals) who have had such an association with an infected person, animal, or contaminated environment as to have had the opportunity to acquire the infection. Contact tracing is a generally accepted method for the control of sexually transmitted diseases.


Head Cancer
UADT Neoplasms
Neoplasms, Neck
Cancer of Neck
Cancer of the Neck
Head Neoplasms
Neck Neoplasms
Cancer of the Head
Neoplasms, Head
Cancer of the Head and Neck
Upper Aerodigestive Tract Neoplasms
Cancer of Head
Head and Neck Cancer
Cancer of Head and Neck
Neck Cancer
Head, Neck Neoplasms
Neoplasms, Upper Aerodigestive Tract
Neoplasms, Head and Neck
Head and Neck Neoplasms

Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)


Zinc Sulfadiazine
Sulfazine
Sulphadiazine
Sulfadiazine
Sulfazin

One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.