Enamel Pellicle
Salivary Pellicle
Dental Pellicle
Salivary Acquired Pellicle

A thin protein film on the surface of DENTAL ENAMEL. It is widely believed to result from the selective adsorption of precursor proteins present in SALIVA onto tooth surfaces, and to reduce microbial adherence to the TEETH.


Health Associations, Mental
Mental Health Associations
Associations, Mental Health

Voluntary organizations which support educational programs and research in psychiatry with the objective of the promotion of mental health. An early association in the United States was founded as the National Committee for Mental Hygiene in 1909, became the Mental Health Association in 1976 and later the National Mental Health Association in 1980. State and local mental health associations in this country are chartered by the national organization and affiliated with it.


Derivatives of valeric acid, including its salts and esters.


Tricho-Rhino-Phalangeal Syndrome Type II

Trichorhinophalangeal Syndrome with Exostoses

Autosomal dominant disorder characterized by cone-shaped epiphyses in the hands and multiple cartilaginous exostoses. INTELLECTUAL DISABILITY and abnormalities of chromosome 8 are often present. The exostoses in this syndrome appear identical to those of hereditary multiple exostoses (EXOSTOSES, HEREDITARY MULTIPLE).


A large increase in oxygen uptake by neutrophils and most types of tissue macrophages through activation of an NADPH-cytochrome b-dependent oxidase that reduces oxygen to a superoxide. Individuals with an inherited defect in which the oxidase that reduces oxygen to superoxide is decreased or absent (GRANULOMATOUS DISEASE, CHRONIC) often die as a result of recurrent bacterial infections.


Intra-Arterial Injections
Injections, Intraarterial
Intraarterial Injections
Injections, Intra-Arterial


Equid Herpesvirus 4
Equine Rhinopneumonitis Virus
EHV-4
Herpesvirus 4, Equid
Equine Herpesvirus 4

A species of VARICELLOVIRUS and the chief cause of rhinopneumonitis in horses.


Group A Chromosomes
Chromosomes, Human, 1-3
Chromosomes A

The large, metacentric human chromosomes, called group A in the human chromosome classification. This group consists of chromosome pairs 1, 2, and 3.


Survival of Motor Neuron 1, Telomeric Protein

An SMN complex protein that contains a TUDOR DOMAIN and is essential for the function of the SMN protein complex. In humans, the protein is encoded by a single gene found near the inversion TELOMERE of a large inverted region of CHROMOSOME 5. Mutations in the gene coding for survival of motor neuron 1 protein may result in SPINAL MUSCULAR ATROPHIES OF CHILDHOOD.


A refined petroleum fraction used as a fuel as well as a solvent.


Octopressin
Felypressin
Phenylalanine Lysine Vasopressin
Octapressin
Vasopressin, Phenylalanyl-Lysyl
PLV-2
Phelypressin

A synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activity.


Subaortic Stenosis, Discrete
Discrete Subaortic Stenosis

A type of constriction that is caused by the presence of a fibrous ring (discrete type) below the AORTIC VALVE, anywhere between the aortic valve and the MITRAL VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.


J1-200-220 Hexabrachion Tenascin-C Cytotactin Tenascin

Hexameric extracellular matrix glycoprotein transiently expressed in many developing organs and often re-expressed in tumors. It is present in the central and peripheral nervous systems as well as in smooth muscle and tendons. (From Kreis & Vale, Guidebook to the Extracellular Matrix and Adhesion Proteins, 1993, p93)


Disasters linked to natural hazards including widespread fires, floods, storms, earthquakes and drought.These events may result in significant damage and loss of lives.


Cyclic Peptides
Peptides, Cyclic
Cyclopeptides
Orbitides
Circular Peptides

Ribosomally synthesized homodetic plant cyclic peptides that have N-to-C amide bonds rather than disulfide bonds.


Cytochromes d
Cytochrome d
Cytochrome d Group

Cytochromes (electron-transporting proteins) with a tetrapyrrolic chelate of iron as a prosthetic group in which the degree of conjugation of double bonds is less than in porphyrin. (From Enzyme Nomenclature, 1992, p539)


Healthcare Surveys
Health Care Surveys
National Hospital Discharge Survey
National Ambulatory Medical Care Survey

Statistical measures of utilization and other aspects of the provision of health care services including hospitalization and ambulatory care.


Thyroid-Stimulating Hormone
TSH (Thyroid Stimulating Hormone)
Thyreotropin
Thyrotropin
Thyrotrophin

A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.


Molecular Targeted Therapy
Targeted Molecular Therapy

Treatments with drugs which interact with or block synthesis of specific cellular components characteristic of the individual's disease in order to stop or interrupt the specific biochemical dysfunction involved in progression of the disease.


Antiretroviral Therapy, Highly Active
Highly Active Antiretroviral Therapy
HAART

Drug regimens, for patients with HIV INFECTIONS, that aggressively suppress HIV replication. The regimens usually involve administration of three or more different drugs including a protease inhibitor.


Stochastic Process
Stochastic Processes
Process, Stochastic

Processes that incorporate some element of randomness, used particularly to refer to a time series of random variables.


Left Ventricular Apical Ballooning Syndrome

A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.


Lichenoid Eruptions
Licheniform Eruptions

Conditions in which there is histological damage to the lower epidermis along with a grouped chronic inflammatory infiltrate in the papillary dermis disturbing the interface between the epidermis and dermis. LICHEN PLANUS is the prototype of all lichenoid eruptions. (From Rook et al., Textbook of Dermatology, 4th ed, p398)


A 2-carbon aldehyde with carbonyl groups on both carbons.


Complement C2a
Complement C2 Fragment a
C2a Complement
Complement C2a Fragment
Complement 2a

The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S. It is a SERINE PROTEASE. C2a combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).


Stromelysin Inhibitors
Gelatinase Inhibitors
MMP Inhibitors
Matrix Metalloproteinase Inhibitors
Collagenase Inhibitors

Compounds that inhibit the enzyme activity or activation of MATRIX METALLOPROTEINASES.


Serotonin Uptake Inhibitors
5-HT Uptake Inhibitors
Serotonin Reuptake Inhibitors
Inhibitors, Serotonin Uptake
Uptake Inhibitors, Serotonin
Uptake Inhibitors, 5-Hydroxytryptamine
Uptake Inhibitors, 5-HT
Reuptake Inhibitors, Serotonin
Selective Serotonin Reuptake Inhibitors
Inhibitors, 5-Hydroxytryptamine Uptake
Inhibitors, Serotonin Reuptake
Inhibitors, 5-HT Uptake
5-Hydroxytryptamine Uptake Inhibitors

Compounds that specifically inhibit the reuptake of serotonin in the brain.


Test, Speech Reception Threshold
Speech Reception Threshold Test

A test to determine the lowest sound intensity level at which fifty percent or more of the spondaic test words (words of two syllables having equal stress) are repeated correctly.


A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.


Rapicidin Tyrocidine Brevicidin Tyrocidines

An antibiotic mixture produced by Bacillus brevis which may be separated into three components, tyrocidines A, B, and C. It is the major constituent (40-60 per cent) of tyrothricin, gramicidin accounting for the remaining 10-20 per cent active material. It is a topical antimicrobial agent, that is very toxic parenterally.


Avian Reoviruses
Orthoreovirus, Avian
Avian orthoreovirus

A species of ORTHOREOVIRUS infecting birds, with outcomes ranging from inapparent to lethal depending on the virus strain and age of the host bird. This species does not infect mammals.


A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.


Woman's Health
Womens Health
Women's Health

The concept covering the physical and mental conditions of women.


Speech, Alaryngeal
Voice Production, Alaryngeal

Methods of enabling a patient without a larynx or with a non-functional larynx to produce voice or speech. The methods may be pneumatic or electronic.


Infections, Fusobacterium
Fusobacterium Infections
Sphaerophorus Infections
Infections, Sphaerophorus
Necrobacillosis

Infections with bacteria of the genus FUSOBACTERIUM.


Inhibitor of DNA replication in gram-positive bacteria.


Point-of-Care
Point of Care Technology
Bedside Computing
Point-of-Care Systems
Bedside Technology

Laboratory and other services provided to patients at the bedside. These include diagnostic and laboratory testing using automated information entry.


Peroxins
Peroxin
Peroxisome Biogenesis Factors

Proteins that are essential for the assembly of PEROXISOMES. They recognize and transport cytoplasmic proteins that contain PEROXISOMAL TARGETING SIGNALS (PTS) to the peroxisome. Mutations in peroxin (PEX) genes are associated with several PEROXISOMAL DISORDERS.


Encephalopathy, Hypertensive
Hypertensive Encephalopathy

Brain dysfunction or damage resulting from sustained MALIGNANT HYPERTENSION. When BLOOD PRESSURE exceeds the limits of cerebral autoregulation, cerebral blood flow is impaired (BRAIN ISCHEMIA). Clinical manifestations include HEADACHE; NAUSEA; VOMITING; SEIZURES; altered mental status (in some cases progressing to COMA); PAPILLEDEMA; and RETINAL HEMORRHAGE.


Spinal Osteochondrosis
Osteochondrosis of Spine

A bone disorder involving ossification centers (EPIPHYSES) of the VERTEBRAL COLUMN.


Tumor Necrosis Factor Receptors
TNF Receptor
Receptors, Tumor Necrosis Factor
Receptors, TNF
Tumor Necrosis Factor Receptor
Cachectin Receptors
Receptors, Cachectin
TNF Receptors

Cell surface receptors that bind TUMOR NECROSIS FACTORS and trigger changes which influence the behavior of cells.


Malted Grain
Seedlings
Sprouts, Plant
Sprouted Seeds
Seedling


Hexadienoic Acid
Potassium Sorbate
Propenylacrylic Acid
Sorbic Acid
Sodium Sorbate

Mold and yeast inhibitor. Used as a fungistatic agent for foods, especially cheeses.


Orofacial Pain
Face Pain
Facial Pain
Pain, Facial
Craniofacial Pain
Neuralgic Facial Pain
Myofacial Pain

Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.


tRNACys
Transfer RNA, Cys
RNA, Transfer, Cys
Cysteine-Specific tRNA
tRNA(Cys)

A transfer RNA which is specific for carrying cysteine to sites on the ribosomes in preparation for protein synthesis.


A pair of nuclei and associated GRAY MATTER in the interpeduncular space rostral to the posterior perforated substance in the POSTERIOR HYPOTHALAMUS.


Immediate Recall
Working Memory
Memory, Short-Term
Memory, Shortterm
Memory, Immediate

Remembrance of information for a few seconds to hours.


Ricin
Ricin B Chain
Ricinus Toxin
RCA 60
Lectin, Ricinus
Castor Bean Lectin
Ricin D
Lectin, Castor Bean
Ricin A Chain
RCA60
Ricin I

A protein phytotoxin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally.


Receptors, G-Protein-Coupled
G-Protein-Coupled Receptors

The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.


Artificial Intra-ocular Implant Dislocation

The shifting and or tilting of implanted artificial lens resulting in impaired vision.


Laws and regulations pertaining to the field of dentistry, proposed for enactment or recently enacted by a legislative body.


Ligamentum Longitudinale
Longitudinal Ligaments
Posterior Longitudinal Ligament
Anterior Longitudinal Ligament

Two extensive fibrous bands running the length of the vertebral column. The anterior longitudinal ligament (ligamentum longitudinale anterius; lacertus medius) interconnects the anterior surfaces of the vertebral bodies; the posterior longitudinal ligament (ligamentum longitudinale posterius) interconnects the posterior surfaces. The commonest clinical consideration is OSSIFICATION OF POSTERIOR LONGITUDINAL LIGAMENT. (From Stedman, 25th ed)


Modifier Gene
Modifier Genes
Genes, Modifier

GENES with ALLELES that affect the PHENOTYPE associated with a nonallelic gene.


Cell growth support structures composed of BIOCOMPATIBLE MATERIALS. They are specially designed solid support matrices for cell attachment in TISSUE ENGINEERING and GUIDED TISSUE REGENERATION uses.


Biological Model
Biological Models
Models, Biological
Models, Biologic
Model, Biological

Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.


A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7 Protein

An ADAMTS protease that contains four central and four C-terminal thrombospondin (TS) motifs. It binds to and degrades CARTILAGE OLIGOMERIC MATRIX PROTEIN.


Calphobindin I
Anchorin CII
Annexin A5
Placental Anticoagulant Protein I
Lipocortin-V
Lipocortin V
Endonexin II
Annexin V

A protein of the annexin family isolated from human PLACENTA and other tissues. It inhibits cytosolic PHOSPHOLIPASE A2, and displays anticoagulant activity.


Complement C3-C5 Convertases, Alternative Pathway

Important enzymes in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. They cleave COMPLEMENT C3 and COMPLEMENT C5.


Energy Resources Conservation
Conservation of Energy Resources

Planned management, use, and preservation of energy resources.


Triple-looped protein domains linked by disulfide bonds. These common structural domains, so-named for their resemblance to Danish pastries known as kringlers, play a role in binding membranes, proteins, and phospholipids as well as in regulating proteolysis. Kringles are also present in coagulation-related and fibrinolytic proteins and other plasma proteinases.


Inosine Polynucleotides
Polyinosinic Acids
Poly I

A group of inosine ribonucleotides in which the phosphate residues of each inosine ribonucleotide act as bridges in forming diester linkages between the ribose moieties.


Regulation, Gene Expression, Enzymologic

Regulation of Gene Expression, Enzymologic

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in enzyme synthesis.


Pseudomonas phage Pf1
Phage Pf1
Pf1 Phage
Bacteriophage Pf1

A species of filamentous Pseudomonas phage in the genus INOVIRUS, family INOVIRIDAE.


Colitis, Mucous
Irritable Bowel Syndrome
Colon, Irritable

A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.


Ensoulment
Beginning of Human Life
Beginning of Life

The point at which religious ensoulment or PERSONHOOD is considered to begin.


Computer-based Information systems having real-time remote access to information or processes.


Body ventilators that assist ventilation by applying intermittent subatmospheric pressure around the thorax, abdomen, or airway and periodically expand the chest wall and inflate the lungs. They are relatively simple to operate and do not require tracheostomy. These devices include the tank ventilators ("iron lung"), Portalung, Pneumowrap, and chest cuirass ("tortoise shell").


A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions.


The sum total of nursing activities which includes assessment (identifying needs), intervention (ministering to needs), and evaluation (validating the effectiveness of the help given).


Core Binding Factors
PEBP2 Transcription Factor
Polyomavirus Enhancer Binding Protein 2
Core-Binding Factor

Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.


Mitogen-Activated Protein Kinase 9
c-jun Kinase-2
JNK2 Stress-Activated Protein Kinase
Stress-Activated Protein Kinase JNK2
MAPK9 Mitogen-Activated Protein Kinase
JNK2 Kinase
c-jun N-terminal Kinase 2

A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 48 and 54 KD exist due to multiple ALTERNATIVE SPLICING.


Medical Director
Director, Medical
Physician Executives
Medical Directors
Directors, Medical

Physicians who serve in a medical and administrative capacity as head of an organized medical staff and who also may serve as liaison for the medical staff with the administration and governing board.


A galectin found preferentially expressed in the gastrointestinal tract. The protein occurs as a homodimer with two 14-kDa subunits.


Slow Reacting Substance of Anaphylaxis
SRS-A

A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a "slow-reacting substance of ANAPHYLAXIS" released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)


Any of the compounds derived from a group of glycols or polyhydroxy alcohols by chlorine substitution for part of the hydroxyl groups. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)


Hypoxanthine-Xanthine Oxidase
Hypoxanthine Dehydrogenase
Xanthine Oxidase
Purine-Xanthine Oxidase
Hypoxanthine Oxidase

An iron-molybdenum flavoprotein containing FLAVIN-ADENINE DINUCLEOTIDE that oxidizes hypoxanthine, some other purines and pterins, and aldehydes. Deficiency of the enzyme, an autosomal recessive trait, causes xanthinuria.


A combination of congenital heart defects consisting of three key features including ATRIAL SEPTAL DEFECTS; PULMONARY STENOSIS; and RIGHT VENTRICULAR HYPERTROPHY.


Dual Diagnosis
Dual Diagnosis, Psychiatric
Psychiatric Dual Diagnosis
Diagnosis, Dual (Psychiatry)
Psychiatric Diagnosis, Dual

The co-existence of a substance abuse disorder with a psychiatric disorder. The diagnostic principle is based on the fact that it has been found often that chemically dependent patients also have psychiatric problems of various degrees of severity.


Aurora Kinases C
Aurora-Ipl1-Related Kinase 3
Serine-Threonine-Protein Kinase 13
Aurora C Kinases
Aurora-Ipl1-Related Protein Kinase
AIK3 Protein Kinase
Aurora Kinase C

Aurora kinase C is a chromosomal passenger protein that interacts with aurora kinase B in the regulation of MITOSIS. It is found primarily in GERM CELLS in the TESTIS, and may mediate CHROMOSOME SEGREGATION during SPERMATOGENESIS.


Healthy Lifestyle
Healthy Lifestyles
Healthy Life Styles
Healthy Life Style

A pattern of behavior involving LIFE STYLE choices which ensure optimum health. Examples are eating right; maintaining physical, emotional, and spiritual wellness, and taking preemptive steps against communicable diseases.


Medical Contraindications
Contraindications, Physical Agent
Contraindications

A condition or factor associated with a recipient that makes the use of a drug, procedure, or physical agent improper or inadvisable.  Contraindications may be absolute (life threatening) or relative (higher risk of complications in which benefits may outweigh risks).


Communication Methods, Total
Total Communication Methods

Utilization of all available receptive and expressive modes for the purpose of achieving communication with the hearing impaired, such as gestures, postures, facial expression, types of voice, formal speech and non-speech systems, and simultaneous communication.


Methods for maintaining or growing CELLS in vitro.


The group in which legal authority is vested for the control of health-related institutions and organizations.


Phospholipase A2
Phospholipases A2
Lecithinase A2

Phospholipases that hydrolyze the acyl group attached to the 2-position of PHOSPHOGLYCERIDES.


Neurasthenic Neuroses
Neuroses, Neurasthenic
Neurasthenia

A mental disorder characterized by chronic fatigue and concomitant physiologic symptoms.


Chronic delayed gastric emptying. Gastroparesis may be caused by motor dysfunction or paralysis of STOMACH muscles or may be associated with other systemic diseases such as DIABETES MELLITUS.


Hair-like extensions on specialized epidermal surfaces of plants which protect against damage from insects, animals, light degradation and fungal infection. Trichomes may also occur on certain unicellular EUKARYOTES.


Tumor Necrosis Factor alpha-Induced Protein 3

A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity.


Ophthalmologic Surgical Procedures
Procedure, Ophthalmologic Surgical
Procedures, Ophthalmologic Surgical
Surgical Procedures, Ophthalmologic
Surgical Procedure, Ophthalmologic
Ophthalmologic Surgical Procedure
Ophthalmological Surgical Procedures

Surgery performed on the eye or any of its parts.


Teaching Rounds
Attending Rounds
Clinical Rounds
Morning Report
Grand Rounds
Morning Rounds

Systematic discussions and TEACHING conducted in HOSPITALS and HEALTHCARE facilities related to patient care.


Syndrome, Congenital Rubella
Rubella Syndrome, Congenital
Congenital Rubella Syndrome

Transplacental infection of the fetus with rubella usually in the first trimester of pregnancy, as a consequence of maternal infection, resulting in various developmental abnormalities in the newborn infant. They include cardiac and ocular lesions, deafness, microcephaly, mental retardation, and generalized growth retardation. (From Dorland, 27th ed)


Duodenogastric Reflux
Duodenal Reflux
Duodeno-Gastric Reflux

Retrograde flow of duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the STOMACH.


Specific Pathogen-Free Organisms
Specific Pathogen Free
Pathogen-Free Organisms

Animals or humans raised in the absence of a particular disease-causing virus or other microorganism. Less frequently plants are cultivated pathogen-free.


Methyl-CCNU MeCCNU Me-CCNU Semustine NSC-95441

4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.


Antivenins Anti-Venoms Anti-Venins Antivenoms

Antisera used to counteract poisoning by animal VENOMS, especially SNAKE VENOMS.


Bucladesine, Disodium Salt
Dibutyryl Cyclic AMP
N',O'-Dibutyryl-cAMP
Dibutyryl Adenosine 3,5 Monophosphate
Bucladesine, Sodium Salt
(But)(2) cAMP
DBcAMP
Bucladesine, Monosodium Salt
Bucladesine, Barium (1:1) Salt
Dibutyryl Adenosine-3',5'-Monophosphate
Bucladesine
N(6),0(2')-Dibutyryl Cyclic AMP

A cyclic nucleotide derivative that mimics the action of endogenous CYCLIC AMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. (From Merck Index, 11th ed)


beta-Endothelial Growth Factor
Endothelial Growth Factors
Endothelial Growth Factor
Endothelial Cell-Derived Growth Factors
Endo-GF
ECDGF
alpha-Endothelial Growth Factor
Endothelial Growth Factor Polypeptides

These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.


Extracellular Calcium-Ion Sensing Receptor

A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-sensing receptors in the PARATHYROID GLANDS play an important role in the maintenance of calcium HOMEOSTASIS by regulating the release of PARATHYROID HORMONE. They differ from INTRACELLULAR CALCIUM-SENSING PROTEINS which sense intracellular calcium levels.


Community Psychiatry
Psychiatry, Community
Social Psychiatry

Branch of psychiatry concerned with the provision and delivery of a coordinated program of mental health care to a specified population. The foci included in this concept are: all social, psychological and physical factors related to etiology, prevention, and maintaining positive mental health in the community.


Film Badge
Film Dosimetry
Film Badge Dosimetry

Use of a device (film badge) for measuring exposure of individuals to radiation. It is usually made of metal, plastic, or paper and loaded with one or more pieces of x-ray film.


Various species of HARES in the genus Lepus, not RABBITS.


Rats, Inbred BN
Rats, BN
Rats, Inbred Brown Norway

An inbred strain of rat that is widely used in a variety of research areas such as the study of ASTHMA; CARCINOGENESIS; AGING; and LEUKEMIA.


Carcinogenic and neurotoxic glycoside occurring in a number of plant species, including Cycas revoluta.


Malnutrition
Malnourishment
Undernutrition
Nutritional Deficiency

An imbalanced nutritional status resulting from insufficient intake of nutrients to meet normal physiological requirement.


Emergency Outpatient Unit
Hospital Service Emergency
Hospital Emergency Service
Emergency Hospital Service
Emergency Room
Emergency Departments
Emergency Service, Hospital
Accident and Emergency Department
Emergency Ward
Service, Hospital Emergency
Emergency Units

Hospital department responsible for the administration and provision of immediate medical or surgical care to the emergency patient.


Youth Sports
Children's Sports
Organized Youth Sports
Adolescent Sports

SPORTS activities designed and/or organized for CHILDREN or YOUTH.


Surgical Fixation Devices
Surgical Fasteners

Devices used to hold tissue structures together for repair, reconstruction or to close wounds. They may consist of adsorbable or non-adsorbable, natural or synthetic materials. They include tissue adhesives, skin tape, sutures, buttons, staples, clips, screws, etc., each designed to conform to various tissue geometries.


Serotonin 2C Receptor
5-HT(2C) Receptor
5-Hydroxytryptamine Type 2C Receptors
Receptor, 5-Hydroxytryptamine Type 2C
5-HT2C Receptor
5-Hydroxytryptamine Type 2C Receptor
Receptor, Serotonin, 5-HT2C

A serotonin receptor subtype found primarily in the CENTRAL NERVOUS SYSTEM and the CHOROID PLEXUS. This receptor subtype is believed to mediate the anorectic action of SEROTONIN, while selective antagonists of the 5-HT2C receptor appear to induce ANXIETY. Several isoforms of this receptor subtype exist, due to adenine deaminase editing of the receptor mRNA.


Kazal Motif
Kazal Domains
Kazal Domain
Kazal Motifs

Highly conserved protein domains characteristic of SERINE PROTEASE INHIBITORS, KAZAL TYPE. They generally occur as tandem repeats, with each domain consisting of approximately 60 amino acids that form a large extended amino acid chain, two short ALPHA-HELICES, and a three-stranded anti-parallel BETA-SHEET. Kazal-like domains also occur in the extracellular portions of AGRIN.


Immunoglobulin gamma-Chain
Immunoglobulin gamma-Chains
gamma Immunoglobulin Heavy Chain
Immunoglobulins, gamma-Chain
gamma Immunoglobulin Heavy Chains
gamma-Chain Immunoglobulins
gamma-2b-Immunoglobulin Heavy Chain
gamma-2a-Immunoglobulin Heavy Chain
gamma-1-Immunoglobulin Heavy Chain

Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.


A group of genetically identical cells all descended from a single common ancestral cell by mitosis in eukaryotes or by binary fission in prokaryotes. Clone cells also include populations of recombinant DNA molecules all carrying the same inserted sequence. (From King & Stansfield, Dictionary of Genetics, 4th ed)


Antigens, CD196
Receptors, CCR6
CC Chemokine Receptors 6
CCR6 Receptors
CC Chemokine Receptor 6
CD196 Antigens

CCR receptors with specificity for CHEMOKINE CCL20. They are expressed at high levels in T-LYMPHOCYTES; B-LYMPHOCYTES; and DENDRITIC CELLS.


A sudden CARDIAC ARRHYTHMIA (e.g., VENTRICULAR FIBRILLATION) caused by a blunt, non-penetrating impact to the precordial region of chest wall. Commotio cordis often results in sudden death without prompt cardiopulmonary defibrillation.


Purinergic Receptor P2X, Ligand-Gated Ion Channel, 2

A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension and NEUROPATHIC PAIN. The receptor comprises three P2X2 subunits. The P2X2 subunits also have been found associated with P2X3 RECEPTOR subunits in a heterotrimeric receptor variant.


Fascicular Block
Left Bundle-Branch Block
Bundle-Branch Block
Posterior Fascicular Block
Anterior Fascicular Block
Right Bundle-Branch Block
Bundle Branch Block

A form of heart block in which the electrical stimulation of HEART VENTRICLES is interrupted at either one of the branches of BUNDLE OF HIS thus preventing the simultaneous depolarization of the two ventricles.


CYP51 Family
CYP51 Enzymes
Cytochrome P450 Family 51

A cytochrome P450 family that occurs in all EUKARYOTES. Its members function in the biosynthesis of STEROIDS and some are targets of ANTIFUNGAL AGENTS.


Rabon Stirofos Tetrachlorvinphos Gardona

An organophosphate cholinesterase inhibitor that is used as an insecticide. It has low mammalian toxicity. (From Merck Index, 11th ed)


Genetic loci which direct transcription of ribosomal RNA in bacterial operons. They are designated rrnB, rrnC, rrnD, etc. according to the structural position of the transcription unit in the DNA sequence.


Chimeras, Transplantation
Transplantation Chimeras
Chimera, Transplantation
Transplantation Chimera

An organism that, as a result of transplantation of donor tissue or cells, consists of two or more cell lines descended from at least two zygotes. This state may result in the induction of donor-specific TRANSPLANTATION TOLERANCE.


The constricted portion of the thigh bone between the femur head and the trochanters.


A derivative of COUMARIN with molecular formula C15H16O9.


Osler-Vaquez Disease
Polycythemia Rubra Vera
Erythremia
Polycythemia Vera
Primary Polycythemia
Polycythemia Ruba Vera

A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.


Xenomelia
Apotemnophilia
Body Integrity Disorder
Amputee Identity Disorder
Foreign Limb Syndrome
Body Integrity Identity Disorder
BIID

Condition in which individuals desire the amputation of one or more healthy limbs or who desire a paralysis.


The separation of individuals or groups resulting in the lack of or minimizing of social contact and/or communication. This separation may be accomplished by physical separation, by social barriers and by psychological mechanisms. In the latter, there may be interaction but no real communication.


Immunofluorescence Technic
Fluorescent Antinuclear Antibody Test
Immunofluorescence
Antinuclear Antibody Test, Fluorescent
Coon's Technique
Immunofluorescence Technique
Fluorescent Protein Tracing
Fluorescent Antibody Technique
Coon's Technic
Fluorescent Antibody Technic

Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.


Genes whose nucleotide sequences overlap to some degree. The overlapped sequences may involve structural or regulatory genes of eukaryotic or prokaryotic cells.


Solute Carrier Family 4, Anion Exchanger, Member 1

Erythrocyte Membrane Anion Transport Protein

Erythrocyte Membrane Protein Band 3, Diego Blood Group

A major integral transmembrane protein of the ERYTHROCYTE MEMBRANE. It is the anion exchanger responsible for electroneutral transporting in CHLORIDE IONS in exchange of BICARBONATE IONS allowing CO2 uptake and transport from tissues to lungs by the red blood cells. Genetic mutations that result in a loss of the protein function have been associated with type 4 HEREDITARY SPHEROCYTOSIS.


Inosine Cyclic Monophosphate
Inosine Cyclic 3',5'-Monophosphate
Cyclic IMP
Inosine Cyclic-3',5'-Monophosphate

Inosine cyclic 3',5'-(hydrogen phosphate). An inosine nucleotide which acts as a mild inhibitor of the hydrolysis of cyclic AMP and cyclic GMP and as an inhibitor of cat heart cyclic AMP phosphodiesterase.


Radiological Health
Health, Radiologic
Radiologic Health

Health concerns associated with the effects of radiation on the environment and on public and personal health.


C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of ESTRADIOL to resemble TESTOSTERONE but less one carbon at the 19 position.


Sulfite Dehydrogenase
Sulphite Cytochrome C Reductase
Sulphite Dehydrogenase
Sulfite Cytochrome C Reductase

An enzyme that catalyzes oxidation of sulfite to sulfate along with the reduction of FERROCYTOCHROME C to FERRICYTOCHROME C.


Controlled vocabulary thesaurus produced by the NATIONAL LIBRARY OF MEDICINE. It consists of sets of terms naming descriptors in a hierarchical structure that permits searching at various levels of specificity.


Shoulder Fractures
Greater Tuberosity Fractures
Humeral Fractures, Proximal

Fractures of the proximal humerus, including the head, anatomic and surgical necks, and tuberosities.


Dried Blood Spot Testing
Dried Blood Spot Method
Dried Blood Spot Analysis

Techniques for using whole blood samples collected on filter paper for a variety of clinical laboratory tests.


Illicit Drugs
Club Drugs
Illegal Drugs
Recreational Drugs
Street Drugs
Drugs, Illegal

Drugs that are manufactured, obtained, or sold illegally. They include prescription drugs obtained or sold without prescription and non-prescription drugs. Illicit drugs are widely distributed, tend to be grossly impure and may cause unexpected toxicity.


Transfusion, White Blood Cell
Transfusions, White Blood Cell
White Blood Cell Transfusion
White Blood Cell Transfusions
Leukocyte Transfusion

The transfer of leukocytes from a donor to a recipient or reinfusion to the donor.


Uveoparotid Fever
Heerfordt Syndrome
Uveoparotitis

A manifestation of sarcoidosis marked by chronic inflammation of the parotid gland and the uvea.


RNA, Heterogeneous Nuclear
hnRNA
Heterogeneous Nuclear RNA

Nuclear nonribosomal RNA larger than about 1000 nucleotides, the mass of which is rapidly synthesized and degraded within the cell nucleus. Some heterogeneous nuclear RNA may be a precursor to mRNA. However, the great bulk of total hnRNA hybridizes with nuclear DNA rather than with mRNA.


The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.


N-Demethylases
Oxidoreductases, N Demethylating
Oxidoreductases, N-Demethylating


Mannopyranoside D-Mannose Mannopyranose Mannose

A hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants. (From Grant & Hackh's Chemical Dictionary, 5th ed & Random House Unabridged Dictionary, 2d ed)


Taeniasis
Infections, Taenia
Taenia Infections

Infection with tapeworms of the genus Taenia.


A type II keratin that is found associated with the KERATIN-10 in terminally differentiated epidermal cells such as those that form the stratum corneum. Mutations in the genes that encode keratin-1 have been associated with HYPERKERATOSIS, EPIDERMOLYTIC.


MeDAB 3'-Methyl-4-dimethylaminoazobenzene Dimethyl-p-(m-tolylazo)aniline Methyldimethylaminoazobenzene


Serine Protease Inhibitor Kazal-Type 5
SPINK5 Protein
Serine Peptidase Inhibitor Kazal-Type 5
LEKTI Protein
Lympho-Epithelial Kazal-Type Inhibitor

A secreted serine peptidase inhibitor that consists of 15 KAZAL MOTIFS and inhibits KALLIKREINS KLK5, KLK7, and KLK14 as well as TRYPSIN. It plays important roles in protecting MUCOSA against infection and inflammation, and in maintaining the integrity of the skin. Mutations in the SPINK5 gene are associated with NETHERTON SYNDROME.


Morgellons Disease
Morgellons
Morgellon's
Morgellons Syndrome

An unexplained illness which is characterized by skin manifestations including non-healing lesions, itching, and the appearance of fibers.


Sodium Channel
Ion Channels, Sodium
Sodium Channels
Ion Channel, Sodium
Sodium Ion Channels

Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.


Silent Mating Type Information Regulation 2 Homolog 3

A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.


Reticular Fibrils
Reticulin
Reticular Fiber
Reticulin Fibers
Reticulin Fibril
Reticulin Fiber
Reticular Fibers
Reticulin Fibrils
Reticular Fibril

A scleroprotein fibril consisting mostly of type III collagen. Reticulin fibrils are extremely thin, with a diameter of between 0.5 and 2 um. They are involved in maintaining the structural integrity in a variety of organs.


Leu-tRNA Ligase
Leucyl T RNA Synthetase
Leucine-tRNA Synthetase
Leucine-tRNA Ligase

An enzyme that activates leucine with its specific transfer RNA. EC 6.1.1.4.


Home Care Aides
Homemaker-Home Health Aides
Home Health Aides

Persons who assist ill, elderly, or disabled persons in the home, carrying out personal care and housekeeping tasks. (From Slee & Slee, Health Care Terms. 2d ed, p202)


Electrogalvanism, Intraoral
Galvanism, Oral

Chemical reaction that occurs when saliva comes into contact with the metals in dental fillings. This reaction can send electric currents through the brain causing negative symptoms.


An acaricide used against many organophosphate and carbamate resistant pests. It acts as an uncoupling agent and monoamine oxidase inhibitor.


Includes ortho-, meta-, and para-nitrophenylgalactosides.


(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II).


CD62L Antigen
Leukocyte Adhesion Molecule, LAM-1
Leu-8 Antigen
TQ1 Antigen
LAM-1
Mel-14 Antigen
Antigens, CD62L
CD62L Antigens
LECAM-1
L Selectin
L-Selectin

Cell adhesion molecule and CD antigen that serves as a homing receptor for lymphocytes to lymph node high endothelial venules.


E1A-Associated p300 Protein
p300 E1A-Associated Coactivator

A member of the p300-CBP transcription factors that was originally identified as a binding partner for ADENOVIRUS E1A PROTEINS.


Polyangium
Polyangiaceae
Myxobacterales
Myxococcales
Myxobacteria
Slime Bacteria

An order of rod-shaped, gram-negative fruiting gliding bacteria found in SOIL; WATER; and HUMUS.


Thyroid Stimulator, Long-Acting
Long-Acting Thyroid Stimulator
LATS

An immunoglobulin G, often found in the blood of hyperthyroid individuals. It stimulates the thyroid for a longer duration than does thyrotoxin and may cause hyperthyroidism in newborns due to placental transmission.


Calcium-binding motifs composed of two helices (E and F) joined by a loop. Calcium is bound by the loop region. These motifs are found in many proteins that are regulated by calcium.


The posterior portion of the avian stomach located between the PROVENTRICULUS and INTESTINE. It consists of a thick muscular wall and small stones (gastroliths) that function to mechanically grind SEEDS and other ingested objects.


Infectious Endophthalmitis
Ophthalmia
Endophthalmitis

Infectious condition of the internal eye.


A psychedelic phenyl isopropylamine derivative, commonly called DOM, whose mood-altering effects and mechanism of action may be similar to those of LSD.


Maf Transcription Factors, Small
Small Maf Transcription Factors

A family of Maf Transcription Factors that lack activation domains. Small Maf proteins function as transcriptional repressors or form heterodimeric complexes to serve as transcriptional coactivators. Small Maf proteins include MafF, MafG, and MafK.


Driver Examination, Automobile
Automobile Driver Examination
Examination, Automobile Driver

Government required written and driving test given to individuals prior to obtaining an operator's license.


Osteoblastoma
Giant Osteoid Osteoma
Osteoma, Giant Osteoid

A benign, painful, tumor of bone characterized by the formation of osteoid tissue, primitive bone and calcified tissue. It occurs frequently in the spine of young persons. (From Dorland, 27th ed; Stedman, 25th ed)


Grafting, Lung
Lung Transplantation
Transplantation, Lung

The transference of either one or both of the lungs from one human or animal to another.


Services provided by dietitians or nutritionists to meet the nutritional needs of individuals, including consultation with other professional personnel.


Dihydrodipicolinic Acid Reductase
Dihydrodipicolinate Reductase

An enzyme that catalyzes the oxidation of 2,3,4,5-tetrahydrodipicolinate to 2,3-dihydrodipicolinate using NAD(P)+ as a cofactor. It is found in BACTERIA and higher plants involved in the biosynthesis of DIAMINOPIMELIC ACID and LYSINE.


Monoclonal Gammopathy of Undetermined Significance

Monoclonal Gammapathy of Undetermined Significance

Conditions characterized by the presence of M protein (Monoclonal protein) in serum or urine without clinical manifestations of plasma cell dyscrasia.


Channel Blockers, Sodium
Sodium Channel Inhibitors
Sodium Channel Blockers

A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.


Mouth Guards
Mouth Pieces, Protective
Mouth Protectors
Mouthpieces, Protective

Devices or pieces of equipment placed in or around the mouth or attached to instruments to protect the external or internal tissues of the mouth and the teeth.


Calcineurin Blockers
Calcineurin Antagonists
Protein Phosphatase 3 Inhibitors
Calcineurin Inhibitors
Protein Phosphatase-2B Inhibitors

Compounds that inhibit or block the PHOSPHATASE activity of CALCINEURIN.


Bruch Membrane
Bruch's Membrane
Lamina Basalis Choroideae
Complexus Basalis

The inner layer of CHOROID, also called the lamina basalis choroideae, located adjacent to the RETINAL PIGMENT EPITHELIUM; (RPE) of the EYE. It is a membrane composed of the basement membranes of the choriocapillaris ENDOTHELIUM and that of the RPE. The membrane stops at the OPTIC NERVE, as does the RPE.


Cellular Inclusions
Cytoplasmic Inclusions
Inclusion Bodies

A generic term for any circumscribed mass of foreign (e.g., lead or viruses) or metabolically inactive materials (e.g., ceroid or MALLORY BODIES), within the cytoplasm or nucleus of a cell. Inclusion bodies are in cells infected with certain filtrable viruses, observed especially in nerve, epithelial, or endothelial cells. (Stedman, 25th ed)


Pyramidal neurons in the HIPPOCAMPUS that play a role in cognitive representation of a specific location within a space.


Vascular Trauma, Brain
Injury, Vascular, Brain
Cerebrovascular Trauma
Vascular Injury, Brain
Brain Injury, Vascular

Penetrating and nonpenetrating traumatic injuries to an extracranial or intracranial blood vessel that supplies the brain. This includes the CAROTID ARTERIES; VERTEBRAL ARTERIES; MENINGEAL ARTERIES; CEREBRAL ARTERIES; veins, and venous sinuses.


Dimethyl Adipinamidate
Dimethyl Adipimidate
Dimethyl Adipimate

Bifunctional cross-linking agent that links covalently free amino groups of proteins or polypeptides, including those in cell membranes. It is used as reagent or fixative in immunohistochemistry and is a proposed antisickling agent.


Auditory Comprehension Disorder
Auditory Processing Disorder
Psychoacoustical Disorders
Auditory Inattention
Auditory Perceptual Disorders
Perceptual Disorders, Auditory
Acoustic Perceptual Disorder

Acquired or developmental cognitive disorders of AUDITORY PERCEPTION characterized by a reduced ability to perceive information contained in auditory stimuli despite intact auditory pathways. Affected individuals have difficulty with speech perception, sound localization, and comprehending the meaning of inflections of speech.


Direct-To-Consumer Screening and Testing

Laboratory testing and diagnostic imaging services offered to consumers outside of the patient-physician relationship.


Wnt Proteins
Wnt Factors
Wingless Type Proteins

Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.


Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS.


A phospholipid-interacting antimalarial drug (ANTIMALARIALS). It is very effective against PLASMODIUM FALCIPARUM with very few side effects.


Vagus Nerve Trauma
Vagus Nerve Injuries
Tenth Cranial Nerve Injuries
Cranial Nerve X Injury
Vagus Nerve Avulsion
Vagus Nerve Contusion
Vagus Nerve Transection
Tenth-Nerve Trauma
Injury, Tenth Cranial Nerve
Tenth Cranial Nerve Injury
Traumatic Tenth-Nerve Palsy
Tenth-Nerve Palsy, Traumatic
Vagus Neuropathy, Traumatic
Injury, Cranial Nerve X

Traumatic injuries to the VAGUS NERVE. Because the vagus nerve innervates multiple organs, injuries in the nerve fibers may result in any gastrointestinal organ dysfunction downstream of the injury site.


Large veins on either side of the root of the neck formed by the junction of the internal jugular and subclavian veins. They drain blood from the head, neck, and upper extremities, and unite to form the superior vena cava.


SLC19a1 Transporter
Solute Carrier Family 19, Member 1
Folate Transporter 1
Reduced Folate Carrier
SLC19a1 Protein
Reduced Folate Carrier Protein

A ubiquitously expressed folic acid transporter that functions via an antiporter mechanism which is coupled to the transport of organic phosphates.


Soft Tissue Injuries
Injuries, Soft Tissue

Injuries of tissue other than bone. The concept is usually general and does not customarily refer to internal organs or viscera. It is meaningful with reference to regions or organs where soft tissue (muscle, fat, skin) should be differentiated from bones or bone tissue, as "soft tissue injuries of the hand".


A type of chromogranin which was initially characterized in a rat PHEOCHROMOCYTOMA CELL LINE. It is found in many species including human, rat, mouse, and others. It is an acidic protein with 626 to 657 amino acid residues. In some species, it inhibits secretion of PARATHYROID HORMONE or INSULIN and exerts bacteriolytic effects in others.


Dental Prosthesis, Implant-Supported
Implant-Supported Dental Prosthesis
Implant-Supported Denture
Prosthesis Dental, Implant-Supported
Denture, Implant-Supported

A prosthesis that gains its support, stability, and retention from a substructure that is implanted under the soft tissues of the basal seat of the device and is in contact with bone. (From Boucher's Clinical Dental Terminology, 4th ed)


Differential, Semantic
Semantic Differential

Analysis of word concepts by the association of polar adjectives, e.g., good-bad, with the concept, father. The adjectives are usually scaled in 7 steps. The subject's placement of the concept on the adjectival scale indicates the connotative meaning of the concept.


Implantation, Heart Valve Prosthesis
Heart Valve Prosthesis Implantation

Surgical insertion of synthetic material to repair injured or diseased heart valves.


Central Supply, Hospital
Hospital Central Supplies
Hospital Central Supply
Supply, Hospital Central
Supplies, Hospital Central

Hospital department responsible for receiving, storing, and distributing medical and surgical supplies and equipment.


Isotretinoin Zinc Salt, 13-cis-Isomer
13-cis-Retinoic Acid
Roaccutane
Accutane
Isotretinoin
Ro 4-3780

A topical dermatologic agent that is used in the treatment of ACNE VULGARIS and several other skin diseases. The drug has teratogenic and other adverse effects.


Carcinoma, Brown-Pearce
Epithelioma, Brown-Pearce

A transplantable EPITHELIAL CELL neoplasm of rabbits.


Synaptophysin
p38 Membrane Protein, Synaptic Vesicle

A MARVEL domain-containing protein found in the presynaptic vesicles of NEURONS and NEUROENDOCRINE CELLS. It is commonly used as an immunocytochemical marker for neuroendocrine differentiation.


Acute pain that comes on rapidly despite the use of pain medication.


Sensitivity, Radiation
Tolerance, Radiation
Radiation Tolerance
Radiosensitivity
Radiation Sensitivity

The ability of some cells or tissues to survive lethal doses of IONIZING RADIATION. Tolerance depends on the species, cell type, and physical and chemical variables, including RADIATION-PROTECTIVE AGENTS and RADIATION-SENSITIZING AGENTS.


Receptor, Tumor Autocrine Motility Factor

Tumor Autocrine Motility Factor Receptor

Cell surface receptors for AUTOCRINE MOTILITY FACTOR, which is the secreted form of GLUCOSE-6-PHOSPHATE ISOMERASE. The receptor has an unusual composition in that it shares some structural similarities with G-PROTEIN-COUPLED RECEPTORS and functions as an ubiquitin protein ligase when internalized.


Myeloid Cell Leukemia Sequence 1 Protein

Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1

A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation.


A plant genus of the family FABACEAE. Members contain STILBENES.


Receptors, Muscarinic M3
Muscarinic Receptors M3
Muscarinic Receptor M3
Receptor, Muscarinic M3

A subclass of muscarinic receptor that mediates cholinergic-induced contraction in a variety of SMOOTH MUSCLES.


Blastomycosis, South American
Paracoccidioidal Granuloma
Paracoccidioidomycosis
Blastomyces brasiliensis Infection
Paracoccidioides brasiliensis Infection

A mycosis affecting the skin, mucous membranes, lymph nodes, and internal organs. It is caused by Paracoccidioides brasiliensis. It is also called paracoccidioidal granuloma. Superficial resemblance of P. brasiliensis to Blastomyces brasiliensis (BLASTOMYCES) may cause misdiagnosis.


Species of tapeworm in the genus TAENIA, that infects swine. It is acquired by humans through the ingestion of cured or undercooked pork.


The region of the lower limb between the FOOT and the LEG.


PGE Receptor, EP1 Subtype
Receptors, Prostaglandin E, EP1 Subtype
Prostaglandin E2 Receptor, EP1 Subtype
Prostanoid Receptor EP1
Prostaglandin E Receptor 1

A subtype of prostaglandin E receptors that specifically couples to GTP-BINDING PROTEIN ALPHA SUBUNIT, GQ and the subsequently activates TYPE C PHOSPHOLIPASES. Additional evidence has shown that the receptor can act through a calcium-dependent signaling pathway.


Evidence-Based Nursing
Nursing, Evidence-Based

A way of providing nursing care that is guided by the integration of the best available scientific knowledge with nursing expertise. This approach requires nurses to critically assess relevant scientific data or research evidence, and to implement high-quality interventions for their nursing practice.


Therapy, PUVA
Psoralen Ultraviolet A Therapy
PUVA Therapy

Photochemotherapy using PSORALENS as the photosensitizing agent and ultraviolet light type A (UVA).


Centers for Health Planning
Organizations, Health Planning
Planning Organizations, Health
Health Planning Organizations

Organizations involved in all aspects of health planning activities.


Plasma Thromboplastin Component Deficiency

A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)


Mep Protein
EphB6 Receptor
Ephrin Receptor EphB6
Receptor, EphB6

An eph family receptor found primarily in BRAIN and THYMUS. The EphB6 receptor is unusual in that its tyrosine kinase domain shares little homology with other members of this class. The unusual tyrosine kinase domain of this receptor appears to result in its lack of tyrosine kinase activity.


Experimental Mammary Neoplasms
Neoplasms, Experimental Mammary
Mammary Neoplasms, Experimental

Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.


Alkylating antineoplastic agent used especially in bladder neoplasms. It is toxic to hair follicles, gastro-intestinal tract, and vasculature.


A syrup made from the dried rhizomes of two different species, CEPHAELIS ipecacuanha and C. acuminata. They contain EMETINE, cephaeline, psychotrine and other ISOQUINOLINES. Ipecac syrup is used widely as an emetic acting both locally on the gastric mucosa and centrally on the chemoreceptor trigger zone.


Material Safety Data Sheets
Material Safety Data Sheet

Information or data used to ensure the safe handling and disposal of substances in the workplace. Such information includes physical properties (i.e. melting, boiling, flashing points), as well as data on toxicity, health effects, reactivity, storage, disposal, first-aid, protective equipment, and spill-handling procedures.


A broad specificity HLA-DR antigen that is associated with HLA-DRB1 CHAINS encoded by DRB1*01:15 and DRB1*01:16 alleles.


Equipment, Diagnostic
Diagnostic Equipment

Nonexpendable items used in examination.


Lipoprotein (a-)
Lipoprotein(a)
Lipoprotein (a)
Lipoprotein Lp(a)
Lipoprotein a

Lipoprotein(a) with the antiangiogenic APOLIPOPROTEIN (A) removed.


An extract from calf blood containing inorganic salts, amino acids, polypeptides and purines, but no proteins nor antigenic substances or blood group characteristics. Its exact composition is unknown. It has been proposed as a radiation-protective agent.


Subacute Sclerosing Panenceph Virus
SSPE Virus

A defective variant of MEASLES VIRUS that has been isolated from the brain tissue of patients with subacute sclerosing panencephalitis.


Nursing Facilities, Skilled
Extended Care Facilities
Facilities, Skilled Nursing
Skilled Nursing Facilities

Extended care facilities which provide skilled nursing care or rehabilitation services for inpatients on a daily basis.


Adrenergic alpha-2 Receptor Antagonists
alpha-2 Adrenergic Blocking Agents
Adrenergic alpha2-Antagonists
Adrenergic alpha-2 Antagonists
alpha2-Adrenergic Antagonists
Adrenergic alpha-2 Receptor Blockers

Drugs that bind to and block the activation of ADRENERGIC ALPHA-2 RECEPTORS.


Esophageal Spasm
Spasm, Esophageal
Esophageal Spasm, Diffuse

A hypermotility disorder of the ESOPHAGUS that is characterized by spastic non-peristaltic responses to SWALLOWING; CHEST PAIN; and DYSPHAGIA.


Cdk5 Protein
Cyclin-Dependent Kinase 5
Cdk5 Protein Kinase
PSSALRE Protein
Cdc2-Related Kinase PSSALRE
Neuronal Cdc2-Like Protein Kinase

A serine-threonine kinase that plays important roles in CELL DIFFERENTIATION; CELL MIGRATION; and CELL DEATH of NERVE CELLS. It is closely related to other CYCLIN-DEPENDENT KINASES but does not seem to participate in CELL CYCLE regulation.


Normal Body Weight
Ideal Body Weight Chart
Ideal Body Mass
Ideal Body Weight Formula
Ideal Body Weight

A method of computing the ideal body weight of an individual


Mastoid Foramen
Mastoid Process
Mastoid Bone
Mastoid

The posterior part of the temporal bone. It is a projection of the petrous bone.


Neuroectodermal Tumor, Melanotic
Retinal Anlage Tumor
Melanoameloblastoma
Progonoma, Melanotic

A benign, rapidly growing, deeply pigmented tumor of the jaw and occasionally of other sites, consisting of an infiltrating mass of cells arranged in an alveolar pattern, and occurring almost exclusively in infants. Its source of origin is in dispute, the various theories giving rise to its several names. (Dorland, 27th ed)


Antidiuretic Hormone Receptor Antagonists

Endogenous compounds and drugs that inhibit or block the activity of ANTIDUIRETIC HORMONE RECEPTORS.


An amphetamine-like anorectic agent. It may cause pulmonary hypertension.


Anterior Commissure of Brain
Anterior Cerebellar Commissure
Anterior Commissure, Brain

Bundle of MYELINATED NERVE FIBERS that connects the two CEREBRAL HEMISPHERES in the LAMINA TERMINALIS. It is located ventral to the SEPTAL NUCLEI, and caudal to the median PREOPTIC NUCLEUS.


A ubiquitinyl hydrolase that deubiquitinates several proteins with critical roles in DNA REPAIR, cell growth, and survival, including TUMOR SUPPRESSOR PROTEIN P53; MDM-2 PROTEIN; and PTEN PHOSPHOHYDROLASE. It also stabilizes herpesvirus 1 trans-acting transcriptional protein VMW110 during HSV-1 infection, contributing to its function as a TRANS-ACTIVATOR.


Acetylcholine Release Inhibitors
Acetylcholine Release Antagonists
Acetylcholine Release Blockers

Compounds that block release of the neurotransmitter ACETYLCHOLINE.


Nursing, Recovery Room
Recovery Room Nursing
Nursing, Postanesthesia
Nursing, Post-Surgical
Postanesthesia Nursing
Nursing, Post-Anesthesia
Post-Anesthesia Nursing
Post-Surgical Nursing

The specialty or practice of nursing in the care of patients in the recovery room following surgery and/or anesthesia.


A macrolide antibiotic of the oligomycin group, obtained from Streptomyces rutgersensis. It is used in cytochemistry as a tool to inhibit various ATPases and to uncouple oxidative phosphorylation from electron transport and also clinically as an antifungal agent.


Skin, Artificial
Artificial Skin
Skin Substitutes

Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.


Deep-Bite
Overbite
Incisor Protrusion
Deep Bite
Over Bite
Overjet, Dental

A malocclusion of the teeth in which maxillary incisor and canine teeth project over the mandiblar teeth. The overlap is measured parallel to the occlusal plane and therefore is called horizontal overlap.


Discrimination, Psychological
Psychological Discrimination
Discrimination, Psychology

Differential response to different stimuli.


Mometasone Furoate Formoterol Fumarate Drug Combination

Mometasone Furoate, Formoterol Fumarate Drug Combination

Mometasone Furoate-Formoterol Fumarate Drug Combination

A pharmaceutical preparation of mometasone furoate and formoterol fumarate that is used as an inhaled dosage form for the treatment of ASTHMA.


Aclarubicin
MA-144A1
Aclaplastin
Aclacin
Aclacinomycin A
NSC-208734

An anthracycline produced by Streptomyces galilaeus. It has potent antineoplastic activity.


Eicosanoid Receptor
Receptors, Eicosanoid
Eicosanoid Receptors
Receptor, Eicosanoids

Cell surface proteins that bind eicosanoids with high affinity and trigger intracellular changes influencing the behavior of cells. Among the eicosanoid receptors are receptors for the prostaglandins, thromboxanes, and leukotrienes.


Transmembrane Protein Deleted in Velocardiofacial Syndrome

A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.


Hypertrophic Subaortic Stenosis, Idiopathic

Obstructive Asymmetric Septal Hypertrophy

An autosomal dominant inherited form of HYPERTROPHIC CARDIOMYOPATHY. It results from any of more than 50 mutations involving genes encoding contractile proteins such as VENTRICULAR MYOSINS; cardiac TROPONIN T; ALPHA-TROPOMYOSIN.


Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.


Pancoast Tumor
Pancoast Syndrome
Pancoast's Syndrome

A lung tumor located in the superior pulmonary sulcus.


A plant genus of the family POACEAE. The common name of buffelgrass is also used for PENNISETUM.


Mouse, Inbred Strain
Inbred Strain of Mice
Inbred Mouse Strains
Mice, Inbred Strains
Inbred Strain of Mouse
Inbred Strains of Mice

Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.


Absorbable Implants
Implants, Absorbable
Biodegradable Implants
Bioabsorbable Implants

Implants constructed of materials designed to be absorbed by the body without producing an immune response. They are usually composed of plastics and are frequently used in orthopedics and orthodontics.


Tanacetum parthenium
Feverfew
Chrysanthemum parthenium

An aromatic perennial plant species that has been used to treat migraines, arthritis, and as a febrifuge. It contains TANNINS, volatile oils (OILS, ESSENTIAL), and sesquiterpene lactones, especially parthenolide.


PKC-alpha Serine-Threonine Kinase
Protein Kinase C(alpha)
Protein Kinase C alpha
Protein Kinase C-alpha

A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.


Cytochrome P-450 CYP26
Cytochrome P450 Family 26
CYP26 Enzymes
CYP26 Family
CYP26 Cytochrome P450

A cytochrome P450 enzyme family whose members function in the metabolism of RETINOIC ACID. It includes RETINOIC ACID 4-HYDROXYLASE.


Progesterone 16 alpha-Hydroxylase
Steroid 16alpha-Hydroxylase
Progesterone-16-alpha-Hydroxylase
16-alpha Hydroxylase
Estrone-3-sulfate 16-alpha Hydroxylase
Estrone 16-alpha Hydroxylase
Steroid 16-alpha-Hydroxylase
Testosterone 16alpha Hydroxylase
16alpha-Hydroxylase
Estrogen 16-alpha Hydroxylase
Testosterone 16-alpha Hydroxylase
Cytochrome P-450(16 alpha)
Estradiol 16-alpha Hydroxylase
Progesterone 16-alpha-Hydroxylase

A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.


Collateral Circulation, Blood
Circulation, Collateral
Collateral Circulation
Collateral Blood Circulation
Blood Circulation, Collateral

Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.


Porcine Epidemic Abortion and Respiratory Syndrome

Swine Infertility and Respiratory Syndrome

Porcine Reproductive and Respiratory Syndrome

A syndrome characterized by outbreaks of late term abortions, high numbers of stillbirths and mummified or weak newborn piglets, and respiratory disease in young unweaned and weaned pigs. It is caused by PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS. (Radostits et al., Veterinary Medicine, 8th ed, p1048)


Cells in the body that store FATS, usually in the form of TRIGLYCERIDES. WHITE ADIPOCYTES are the predominant type and found mostly in the abdominal cavity and subcutaneous tissue. BROWN ADIPOCYTES are thermogenic cells that can be found in newborns of some species and hibernating mammals.


Nursing practice limited to an office setting.


VAMP3
Synaptobrevin 3
Vesicle-Associated Membrane Protein 3
Cellubrevin

A member of the vesicle associated membrane protein family. It has a broad tissue distribution and is involved in MEMBRANE FUSION events of the endocytic pathways.


The degree to which BLOOD VESSELS are not blocked or obstructed.


3-Ketoacyl CoA Thiolase
2-Methylacetoacetyl CoA Thiolase
3-Ketothiolase
3-Oxoacyl-Coenzyme A Thiolase
Acetyl CoA Acyltransferase
3-Oxoacyl CoA Thiolase
beta-Ketoacyl Thiolase
Acetyl Coenzyme A Acyltransferase
Acetyl-CoA C-Acyltransferase
beta-Ketothiolase

Enzyme that catalyzes the final step of fatty acid oxidation in which ACETYL COA is released and the CoA ester of a fatty acid two carbons shorter is formed.


Signal Detection Analysis
Signal Detection (Psychology)
Signal Detection, Psychological
Signal Detection Theory

Psychophysical technique that permits the estimation of the bias of the observer as well as detectability of the signal (i.e., stimulus) in any sensory modality. (From APA, Thesaurus of Psychological Index Terms, 8th ed.)


A plant genus of the family FABACEAE. Members contain karanjin. Some species of this genus have been reclassified to other genera of FABACEAE including Callerya, DERRIS and MILLETTIA.


P450 CYP2E1 Inducers
CYP2E1 Inducers
Cytochrome P-450 CYP2E1 Inducers

Drugs and compounds that induce the synthesis of CYTOCHROME P-450 CYP2E1.


The moral obligations governing the conduct of research. Used for discussions of research ethics as a general topic.


A totalitarian system of government in which a single authoritarian party controls state-owned means of production with the professed aim of establishing a classless society.


Mucosal-Associated Invariant T Cells
MAIT Cells

A subset of T-lymphocytes that are present in large numbers at MUCOUS MEMBRANES and respond to INFECTIONS. They express a conserved invariant T-CELL RECEPTOR ALPHA-CHAIN that enables them to respond to infections by sensing RIBOFLAVIN metabolites of pathogens.


Culture of an isolated organism free from any other associating or contaminating organisms.


A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.


Protease Antagonists
Peptidase Inhibitors
Protease Inhibitor
Endopeptidase Inhibitors
Protease Inhibitors
Peptide Peptidohydrolase Inhibitors
Peptide Hydrolase Inhibitors
Antiproteases

Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).


Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine

A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards T LYMPHOCYTES and B LYMPHOCYTES.


Hybridization in Situ
In Situ Hybridization

A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.


Traumatic Subarachnoid Hemorrhage
Post-Traumatic Subarachnoid Hemorrhage
Subarachnoid Hemorrhage, Traumatic

Bleeding into the SUBARACHNOID SPACE due to CRANIOCEREBRAL TRAUMA. Minor hemorrhages may be asymptomatic; moderate to severe hemorrhages may be associated with INTRACRANIAL HYPERTENSION and VASOSPASM, INTRACRANIAL.


Neuronal Precursor Cell-Expressed Developmentally Down-Regulated 4 Ligase

E3 ubiquitin ligases that consist of four WW DOMAINS. They accept UBIQUITIN from E2 UBIQUITIN-CONJUGATING ENZYME as a thioester via their C-terminal HECT domains and transfer it specifically to the 63rd LYSINE residue (Lys-63) of target proteins. NEDD4 targets include many proteins and receptors with important functions for cell growth and homeostasis such as VEGFR-2; FGFR1 TYROSINE KINASE; and ERBB-4 RECEPTOR. They play a critical role in the internalization of these receptors, their degradation by LYSOSOMES, and also function as part of the ESCRT complex in VIRUS RELEASE.


An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.


A common name (but used formally) for a group of organisms that are mostly kinds of algae including BACILLARIOPHYTA; OOMYCETES; PHAEOPHYCEAE; and CHRYSOPHYCEAE. They all contain CHLOROPLASTS that are thought to have been derived from the endosymbiosis of ancient RED ALGAE.


Low-Density Lipoprotein Receptor-Related Protein-2

Low Density Lipoprotein Receptor-Related Protein-2

An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in that it binds to a variety of ligands with relatively high affinity and may function in mediating the uptake and lysosomal degradation of macromolecules such as: LIPOPROTEINS; ENDOPEPTIDASES; and PROTEASE INHIBITORS.


Vanillic Acid
p-Hydroxy-m-methoxy-benzoic Acid
4-Hydroxy-3-methoxybenzoic Acid

A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).


Hindlimb Suspension
Skeletal Unloading
Hindlimb Elevation
Tail Suspension
Hindlimb Unloading
Hindlimb Immobilization

This refers to skeletal muscle usually related to the hindlimb.


Patterns associated with eating including modes of feeding, rhythmic patterns of eating, and time intervals.


Intracoronal Attachment
Slotted Attachment, Dental
Dental Slotted Attachment
Precision Attachment, Denture
Denture Precision Attachment
Attachment, Dental Slotted
Denture, Precision Attachment
Dental Slotted Attachments
Attachments, Dental Slotted
Slotted Attachments, Dental

A precision device used for attaching a fixed or removable partial denture to the crown of an abutment tooth or a restoration. One type is the intracoronal attachment and the other type is the extracoronal attachment. It consists of a female portion within the coronal portion of the crown of an abutment and a fitted male portion attached to the denture proper. (Jablonski, Dictionary of Dentistry, 1992, p85; from Boucher's Clinical Dental Terminology, 4th ed, p264)


Intravascular Coagulation, Disseminated
Coagulation, Disseminated Intravascular
Disseminated Coagulation, Intravascular
Intravascular Disseminated Coagulation
Consumption Coagulopathy
Disseminated Intravascular Coagulation

A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.


Prostaglandin E2 Receptor, EP3 Subtype
Receptors, Prostaglandin E, EP3 Subtype
PGE Receptor, EP3 Subtype
Prostaglandin E Receptor 3
Prostanoid Receptor EP3

A subtype of prostaglandin E receptors that specifically couples to GTP-BINDING PROTEIN ALPHA SUBUNIT, GI and subsequently inhibits ADENYLYL CYCLASES.


Infectious Hepatitis
Hepatitis A
Hepatitis, Infectious

INFLAMMATION of the LIVER in humans caused by a member of the HEPATOVIRUS genus, HUMAN HEPATITIS A VIRUS. It can be transmitted through fecal contamination of food or water.


Dihydroxybutanes
Butylene Glycols
Butanediols

4-carbon straight chain aliphatic hydrocarbons substituted with two hydroxyl groups. The hydroxyl groups cannot be on the same carbon atom.


Tyrosine-Protein Kinase HCK
Proto-Oncogene Protein hck
c-hck Proteins
c-hck Proto-Oncogene Proteins
Proto-Oncogene Proteins c-hck
hck Proto-Oncogene Proteins
Hematopoietic Cell Kinase
Proto-Oncogene Protein c-hck

Members of the src-family tyrosine kinase family that are strongly expressed in MYELOID CELLS and B-LYMPHOCYTES.


Casein Kinase I alpha
Casein Kinase Ialpha
Casein Kinase IalphaL
Casein Kinase IalphaS
Casein Kinase IalphaLS

A casein kinase I isoenzyme that plays a role in intracellular signaling pathways including the WNT SIGNALING PATHWAY, the CELL CYCLE, membrane trafficking, and RNA processing. Multiple isoforms of casein kinase I alpha exist and are due to ALTERNATIVE SPLICING.


Gangliosidoses, GM2
Gangliosidoses GM2
GM2 Gangliosidosis
G(M2) Gangliosidoses

A group of recessively inherited diseases characterized by the intralysosomal accumulation of G(M2) GANGLIOSIDE in the neuronal cells. Subtypes include mutations of enzymes in the BETA-N-ACETYLHEXOSAMINIDASES system or G(M2) ACTIVATOR PROTEIN leading to disruption of normal degradation of GANGLIOSIDES, a subclass of ACIDIC GLYCOSPHINGOLIPIDS.


A synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents (ORAL CONTRACEPTIVES, COMBINED).


Bradykinin Type 1 Receptor
Bradykinin B1 Receptors
Bradykinin B1 Receptor
Receptor, Bradykinin B1

A subtype of BRADYKININ RECEPTOR that is induced in response to INFLAMMATION. It may play a role in chronic inflammation and has a high specificity for KININS lacking the C-terminal ARGININE such as des-Arg(10)-kallidin and des-Arg(9)-bradykinin. The receptor is coupled to G-PROTEIN, GQ-G11 ALPHA FAMILY and G-PROTEIN, GI-GO ALPHA FAMILY signaling proteins.


Psychological Set
Set, Psychology
Set (Psychology)

Readiness to think or respond in a predetermined way when confronted with a problem or stimulus situation.


Delayed Rectifier Potassium Channels
Delayed Rectifying Potassium Channels

A group of slow opening and closing voltage-gated potassium channels. Because of their delayed activation kinetics they play an important role in controlling ACTION POTENTIAL duration.


Animal Testing Alternatives
Alternatives to Animal Testing

Procedures, such as TISSUE CULTURE TECHNIQUES; mathematical models; etc., when used or advocated for use in place of the use of animals in research or diagnostic laboratories.


Elastica
Vulcanite
Natural Rubber
Latex Rubber
Plant Rubber
Rubber
India Rubber

A high-molecular-weight polymeric elastomer derived from the milk juice (LATEX) of HEVEA brasiliensis and other trees and plants. It is a substance that can be stretched at room temperature to at least twice its original length and after releasing the stress, retract rapidly, and recover its original dimensions fully.


A nucleus in the pons with exon projections to the sacral parasympathetic nucleus associated with bladder control.


Osteoclastic Bone Loss
Bone Resorption
Bone Loss, Osteoclastic


S-adenosylhomocysteine Synthase
SAH Hydrolase
S-adenosylhomocysteine Hydrolase
Adenosylhomocysteinase

An enzyme which catalyzes the catabolism of S-ADENOSYLHOMOCYSTEINE to ADENOSINE and HOMOCYSTEINE. It may play a role in regulating the concentration of intracellular adenosylhomocysteine.


Mannose-Binding Lectin
Mannose-Binding Protein
Mannan-Binding Protein
Mannan-Binding Lectin

A specific mannose-binding member of the collectin family of lectins. It binds to carbohydrate groups on invading pathogens and plays a key role in the MANNOSE-BINDING LECTIN COMPLEMENT PATHWAY.


Ethylmesylate
Ethyl Methanesulfonate
Ethylmethane Sulfonate
Ethylmesilate
Ethyl Mesilate
Ethyl Mesylate

An antineoplastic agent with alkylating properties. It also acts as a mutagen by damaging DNA and is used experimentally for that effect.


Neoplasms, Multiple Endocrine
Multiple Endocrine Adenomatosis
Endocrine Neoplasia, Multiple
Multiple Endocrine Neoplasia
Multiple Endocrine Neoplasia Syndromes
Adenomatosis, Familial Endocrine
Familial Endocrine Adenomatosis
Neoplasia, Multiple Endocrine
Multiple Endocrine Neoplasms
Adenomatosis, Multiple Endocrine
Multiple Endocrine Adenopathy

A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.


Dual Specificity Phosphatase 2
PAC-1 Phosphatase
PAC1 Phosphatase

A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for EXTRACELLULAR SIGNAL-REGULATED MAP KINASES and is primarily localized to the CELL NUCLEUS.


Thyroid Stimulating Antibody
Thyroid-Stimulating Immunoglobulins
Thyroid-Stimulating Immunoglobulin
Ig Thyroid Stimulating
Immunoglobulin, Thyroid-Stimulating
Immunoglobulins, Thyroid-Stimulating
Antibodies, Thyroid-Stimulating
Thyroid-Stimulating Antibodies

Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.


Bacterial Infections, Central Nervous System

Infections, Bacterial, Central Nervous System

Central Nervous System Bacterial Infections

Bacterial infections of the brain, spinal cord, and meninges, including infections involving the perimeningeal spaces.


Codon, Start
Initiator Codon
Codon, Initiation
Codon, Initiator
Start Codon

A codon that directs initiation of protein translation (TRANSLATION, GENETIC) by stimulating the binding of initiator tRNA (RNA, TRANSFER, MET). In prokaryotes, the codons AUG or GUG can act as initiators while in eukaryotes, AUG is the only initiator codon.


Aplastic Anemia
Anemia, Hypoplastic
Aplastic Anaemia
Anemia, Aplastic

A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.


Plasma glycoproteins that form a stable complex with hemoglobin to aid the recycling of heme iron. They are encoded in man by a gene on the short arm of chromosome 16.


Neutrophilic Eccrine Hidradenitis
Hydradenitis
Hidradenitis
Hidrosadenitis

The inflammation of a sweat gland (usually of the apocrine type). The condition can be idiopathic or occur as a result of or in association with another underlying condition. Neutrophilic eccrine hidradenitis is a relatively rare variant that has been reported in patients undergoing chemotherapy, usually for non-Hodgkin lymphomas or leukemic conditions.


Derivatives of PHOSPHATIDYLCHOLINES obtained by their partial hydrolysis which removes one of the fatty acid moieties.


Gene Rearrangement, delta-Chain T-Cell Antigen Receptor

T Lymphocyte delta-Chain Gene Rearrangement

T-Cell Antigen Receptor delta-Chain Gene Rearrangement

Gene Rearrangement, delta-Chain T Cell Antigen Receptor

T-Lymphocyte Antigen Receptor delta-Chain Gene Rearrangement

Ordered rearrangement of T-cell variable gene regions coding for the delta-chain of antigen receptors.


Capping, Pulp
Pulp Capping, Dental
Capping, Dental Pulp
Pulp Capping
Dental Pulp Capping

Application of a protective agent to an exposed pulp (direct capping) or the remaining thin layer of dentin over a nearly exposed pulp (indirect capping) in order to allow the pulp to recover and maintain its normal vitality and function.


Optical Devices
Optical System
Optical Components

A specific collection of optical components configured to detect, analyze, or manipulate light.


Muscle Fibers, Type I
Muscle Fibers, Slow-Twitch
Muscle Fibers, Red

Skeletal muscle fibers characterized by their expression of the Type I MYOSIN HEAVY CHAIN isoforms which have low ATPase activity and effect several other functional properties - shortening velocity, power output, rate of tension redevelopment.


Irritant Dermatitis
Dermatitis, Irritant
Dermatitis, Primary Irritant

A non-allergic contact dermatitis caused by prolonged exposure to irritants and not explained by delayed hypersensitivity mechanisms.


Formed by the articulation of the talus with the calcaneus.


DAZ-1 Protein
Deleted in Azoospermia 1 Protein
SPGY Protein
DAZ1 Protein

An RNA recognition motif protein that is essential for SPERMATOGENESIS. It promotes entry of male GERM CELLS to MEIOSIS, possibly by regulating the translation of mRNAs. DAZ1 occurs within a cluster of similar genes on the Y CHROMOSOME that is prone to genetic deletions and duplications. Deletions in these genes, including DAZ1, are associated with AZOOSPERMIA and OLIGOSPERMIA.


A class of phosphotransferases that catalyzes the transfer of diphosphate-containing groups. EC 2.7.6.


Neuritis, Sensory
Neuritis
Neuritis, Motor
Neuritis, Peripheral
Polyneuritis


Enisyl
Lysine Hydrochloride
L-Lysine
Lysine
Lysine Acetate

An essential amino acid. It is often added to animal feed.


Pathological conditions in the INTESTINES that are characterized by the gastrointestinal loss of serum proteins, including SERUM ALBUMIN; IMMUNOGLOBULINS; and at times LYMPHOCYTES. Severe condition can result in HYPOGAMMAGLOBULINEMIA or LYMPHOPENIA. Protein-losing enteropathies are associated with a number of diseases including INTESTINAL LYMPHANGIECTASIS; WHIPPLE'S DISEASE; and NEOPLASMS of the SMALL INTESTINE.


2-amino-4-mercaptobutyric acid
Homocysteine
Homocysteine, L-Isomer

A thiol-containing amino acid formed by a demethylation of METHIONINE.


Chromosomes, Human, Pair 17
Chromosome 17

A specific pair of GROUP E CHROMOSOMES of the human chromosome classification.


L-Carnosine
Carnosine
beta-Alanylhistidine
Carnosine, (D-His)-Isomer
Carnosine Hydrochloride

A naturally occurring dipeptide neuropeptide found in muscles.


Hypnoanesthesia
Hypnosis, Anesthetic
Hypnosedation

Procedure in which an individual is induced into a trance-like state to relieve pain. This procedure is frequently performed with local but not general ANESTHESIA.


Infections, Filarioidea
Filarioidea Infections
Elaeophoriasis
Filariasis

Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.


A mobile chain of three small bones (INCUS; MALLEUS; STAPES) in the TYMPANIC CAVITY between the TYMPANIC MEMBRANE and the oval window on the wall of INNER EAR. Sound waves are converted to vibration by the tympanic membrane then transmitted via these ear ossicles to the inner ear.


An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.


A variation from the normal set of chromosomes characteristic of a species.


A pattern recognition receptor that binds FLAGELLIN. It mediates cellular responses to certain bacterial pathogens.


Phosphotriesterase
Phosphoric Triester Hydrolases

A class of enzymes that catalyze the hydrolysis of one of the three ester bonds in a phosphotriester-containing compound.


Adenosine A1 Receptors
Receptor, Adenosine A1
Adenosine A1 Receptor

A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of tissues including the BRAIN and DORSAL HORN NEURONS. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.


Narrowing of the pyloric canal with varied etiology. A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants.


Infectious Myelitis
Inflammation, Spinal Cord
Myelitis
Subacute Necrotizing Myelitis
Myelopathy, Inflammatory
Spinal Cord Inflammation

Inflammation of the spinal cord. Relatively common etiologies include infections; AUTOIMMUNE DISEASES; SPINAL CORD; and ischemia (see also SPINAL CORD VASCULAR DISEASES). Clinical features generally include weakness, sensory loss, localized pain, incontinence, and other signs of autonomic dysfunction.


Hydroxycinnamic acid and its derivatives. Act as activators of the indoleacetic acid oxidizing system, thereby producing a decrease in the endogenous level of bound indoleacetic acid in plants.


A strain of ENCEPHALOMYOCARDITIS VIRUS, a species of CARDIOVIRUS, that infects rodents.


Enzymes that catalyze a reverse aldol condensation. A molecule containing a hydroxyl group and a carbonyl group is cleaved at a C-C bond to produce two smaller molecules (ALDEHYDES or KETONES). EC 4.1.2.


Felis catus
Felis sylvestris catus
Felis domesticus
Cats
Domestic Cats
Felis domestica

The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)


Study Guide as Topic
Study Guides as Topic

Works about use of aids to help facilitate learning and comprehension of a topic or to help prepare for an examination.


Pseudo-Exfoliation Syndrome
Exfoliation Glaucoma
Pseudoexfoliation Of The Lens
Exfoliative Syndrome
Glaucoma Capsulare
Exfoliation Syndrome
Pseudoexfoliation Syndrome

The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380)


A family of galactoside hydrolases that hydrolyze compounds with an O-galactosyl linkage. EC 3.2.1.-.


Methicillin Resistant Staphylococcus aureus

A strain of Staphylococcus aureus that is non-susceptible to the action of METHICILLIN. The mechanism of resistance usually involves modification of normal or the presence of acquired PENICILLIN BINDING PROTEINS.


4-Methylpyrazole Monohydrochloride
Fomepizole
4-Methylpyrazole
Antizol

A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.


The common name for the phylum of microscopic unicellular STRAMENOPILES. Most are aquatic, being found in fresh, brackish, and salt water. Diatoms are noted for the symmetry and sculpturing of their siliceous cell walls. They account for 40% of PHYTOPLANKTON, but not all diatoms are planktonic.


Ratio of T-LYMPHOCYTES that express the CD4 ANTIGEN to those that express the CD8 ANTIGEN. This value is commonly assessed in the diagnosis and staging of diseases affecting the IMMUNE SYSTEM including HIV INFECTIONS.


Adult-Onset Still Disease
Still's Disease, Adult-Onset
Adult-Onset Still's Disease
Still Disease, Adult-Onset

Systemic-onset rheumatoid arthritis in adults. It differs from classical rheumatoid arthritis in that it is more often marked by acute febrile onset, and generalized lymphadenopathy and hepatosplenomegaly are more prominent.


G-T Mismatch-Specific Thymine DNA Glycosylase

An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine.


ADF Proteins (Actin Depolymerizing Factors)

A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.


Anti-Allergy Drugs
Antiallergic Drugs
Anti-Allergics
Antiallergy Agents
Anti-Allergic Agents
Antiallergics
Antiallergic Agents

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)


A metabolite of TESTOSTERONE or ANDROSTENEDIONE with a 3-alpha-hydroxyl group and without the double bond. The 3-beta hydroxyl isomer is epiandrosterone.


Bacteriophages, RNA
Phages, RNA
RNA Phages

Bacteriophages whose genetic material is RNA, which is single-stranded in all except the Pseudomonas phage phi 6 (BACTERIOPHAGE PHI 6). All RNA phages infect their host bacteria via the host's surface pili. Some frequently encountered RNA phages are: BF23, F2, R17, fr, PhiCb5, PhiCb12r, PhiCb8r, PhiCb23r, 7s, PP7, Q beta phage, MS2 phage, and BACTERIOPHAGE PHI 6.


Carbon Flux
Carbon Cycle
Carbon Fixation

The cycle by which the element carbon is exchanged between organic matter and the earth's physical environment.


A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).


High temperature destruction of waste by burning with subsequent reduction to ashes or conversion to an inert mass.


Troponin I3
Troponin I
Troponin I1
Troponin I2
Troponin-I

A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.


NF-kappa B
NF-kappaB
Nuclear Factor kappa B
Immunoglobulin Enhancer-Binding Protein
Ig-EBP-1
NF-kB
Transcription Factor NF-kB
kappa B Enhancer Binding Protein
Nuclear Factor-Kappab

Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.


1-Acylglycerol Phosphate Acyltransferase 2

An enzyme that catalyzes the acyl group transfer of ACYL COA to 1-acyl-sn-glycerol 3-phosphate to generate 1,2-diacyl-sn-glycerol 3-phosphate. This enzyme has alpha, beta, gamma, delta and epsilon subunits.


EphA5 Receptor
Receptor, EphA5
EphA5 Protein
Brain-Specific Kinase
bsk Tyrosine Kinase

An eph family receptor found primarily in differentiated neuronal tissues. Several isoforms of EphA5 receptor occur due to multiple alternative RNA splicing. The protein is prominently expressed in the NEURONS of the LIMBIC SYSTEM during development and throughout adult life, suggesting its role in the plasticity of limbic structure and function.


Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.


Calciphylaxes
Calciphylaxis
Idiopathic Calciphylaxis

Condition of induced systemic hypersensitivity in which tissues respond to appropriate challenging agents with a sudden local calcification.


Protein components on the surface of LIPOPROTEINS. They form a layer surrounding the hydrophobic lipid core. There are several classes of apolipoproteins with each playing a different role in lipid transport and LIPID METABOLISM. These proteins are synthesized mainly in the LIVER and the INTESTINES.


Triosephosphate Mutase
Phosphotriose Isomerase
Triosephosphate Isomerase
Triose-Phosphate Isomerase

An enzyme that catalyzes reversibly the conversion of D-glyceraldehyde 3-phosphate to dihydroxyacetone phosphate. A deficiency in humans causes nonspherocytic hemolytic disease (ANEMIA, HEMOLYTIC, CONGENITAL NONSPHEROCYTIC). EC 5.3.1.1.


Myeloma-Multiple
Kahler Disease
Myelomatosis
Myeloma, Multiple
Plasma Cell Myeloma
Multiple Myeloma
Myeloma, Plasma-Cell

A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.


Illegal Behavior
Criminal Behavior
Unlawful Behavior
Illicit Behavior
Criminal Conduct
Criminal Intent

Conduct leading to commission of unlawful acts.


Disruptive, Impulse Control, and Conduct Disorders

Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.


Sensorimotor Area
Sensory-Motor Area
Sensory Motor Cortex
Sensorimotor Cortex
Sensory Motor Area
Sensory-Motor Cortex

A composite area of the cerebral cortex concerned with motor control and sensory perception comprising the motor cortex areas, the somatosensory areas, the gustatory cortex, the olfactory areas, the auditory cortex, and the visual cortex.


Melanocyte-Stimulating Hormone Release-Inhibiting Factor

Melanocyte-Stimulating Hormone Release-Inhibiting Hormone

A hypothalamic tripeptide, enzymatic degradation product of OXYTOCIN, that inhibits the release of MELANOCYTE-STIMULATING HORMONES.


Labor, Induced
Induction of Labor
Labor Induced
Induced Labor
Labor Induction

Artificially induced UTERINE CONTRACTION.


Persons who perform certain functions under the supervision of a pharmacist.


Sex Pili
Sex Pilus
Pili, Conjugative
Conjugative Pili
Pili, Sex

Filamentous or elongated proteinaceous structures which extend from the cell surface in gram-negative bacteria that contain certain types of conjugative plasmid. These pili are the organs associated with genetic transfer and have essential roles in conjugation. Normally, only one or a few pili occur on a given donor cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed, p675) This preferred use of "pili" refers to the sexual appendage, to be distinguished from bacterial fimbriae (FIMBRIAE, BACTERIAL), also known as common pili, which are usually concerned with adhesion.


v-mos Genes
v-mos Oncogenes
mos Genes
c-mos Proto-Oncogenes
mos Proto-Oncogenes
Genes, mos
c-mos Genes
mos Oncogenes

Retrovirus-associated DNA sequences (mos) originally isolated from the Moloney murine sarcoma virus (Mo-MSV). The proto-oncogene mos (c-mos) codes for a protein which is a member of the serine kinase family. There is no evidence as yet that human c-mos can become transformed or has a role in human cancer. However, in mice, activation can occur when the retrovirus-like intracisternal A-particle inserts itself near the c-mos sequence. The human c-mos gene is located at 8q22 on the long arm of chromosome 8.


Dental cements composed either of polymethyl methacrylate or dimethacrylate, produced by mixing an acrylic monomer liquid with acrylic polymers and mineral fillers. The cement is insoluble in water and is thus resistant to fluids in the mouth, but is also irritating to the dental pulp. It is used chiefly as a luting agent for fabricated and temporary restorations. (Jablonski's Dictionary of Dentistry, 1992, p159)