A genus of tapeworm, containing several species, found as adults in birds and mammals. The larvae or cysticercoid stage develop in invertebrates. Human infection has been reported and is probably acquired from eating inadequately cooked meat of animals infected with the second larval stage known as the tetrahythridium.


Cardiac Resynchronization Therapy Devices

Artificial pacemakers with implantable leads to be placed in the RIGHT ATRIUM and both HEART VENTRICLES. They are used to treat various cardiac conduction disturbances which interfere with the timing of contraction of the ventricles.


An isoform of DNA that occurs under experimental conditions. It is a right-handed helix that is less compact than the B-form of DNA.


Numeric or quantitative entities, descriptions, properties, relationships, operations, and events.


Branch of agriculture which involves the cultivation of vegetables, flowers, or ornamental plants for food, industrial, medicinal, or aesthetic purposes. It does not include CROP PRODUCTION on a large scale.


A family of gram-negative, moderately halophilic bacteria in the order Oceanospirillales. Members of the family have been isolated from temperate and Antarctic saline lakes, solar salt facilities, saline soils, and marine environments.


Highly conserved protein domains of approximately 130 to 140 amino acids. The SET domain was first identified in the Drosophila proteins (S)u(var)3-9, (E)nhancer-of-zeste and (T)rithorax and occurs in other proteins with a variety of functions, including histone-lysine N-methyltransferases. Structurally, it consists of BETA-SHEETS interspersed among loops and turns that result in an "L" shape. The most conserved motifs are a stretch at the C-terminal that contains a strictly conserved tyrosine residue and an adjacent loop that the C-terminal segment passes through to form a "knot". These motifs and especially the tyrosine residue are essential for S-ADENOSYLMETHIONINE binding and catalysis. The PR domain has high homology to the catalytic region of the SET domain and occurs at the N-terminal of PRDM proteins such as PRDM1 PROTEIN.


Devices in which blood and oxygen are separated by a semipermeable membrane, generally of Teflon or polypropylene, across which gas exchange occurs. The membrane may be arranged as a series of parallel plates or as a number of hollow fibers; in the latter arrangement, the blood may flow inside the fibers, which are surrounded by gas, or the blood may flow outside the fibers and the gas inside the fibers. (Dorland, 28th ed)


A network of nerve fibers originating in the upper four CERVICAL SPINAL CORD segments. The cervical plexus distributes cutaneous nerves to parts of the neck, shoulders, and back of the head. It also distributes motor fibers to muscles of the cervical SPINAL COLUMN, infrahyoid muscles, and the DIAPHRAGM.


The biological objects that contain genetic information and that are involved in transmitting genetically encoded traits from one organism to another.


An element of the rare earth family of metals. It has the atomic symbol Y, atomic number 39, and atomic weight 88.91. In conjunction with other rare earths, yttrium is used as a phosphor in television receivers and is a component of the yttrium-aluminum garnet (YAG) lasers.


Gastric Mucosa
Cardiac Glands
Pyloric Glands
Gastric Glands

Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones.


A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)


Gastric Artery
Left Gastric Artery
Right Gastric Artery

Any of several branches of the SPLENIC ARTERY distributed to the greater curvature of the stomach.


A feeling of self-consciousness, shame, or awkwardness.


An extremely rare condition manifested as monoclonal IMMUNOGLOBULIN M dysproteinemia without features of lymphoproliferative disease, but with chronic urticaria, fever of unknown origin, disabling bone pain, hyperostosis, and increased erythrocyte sedimentation rate.


A small round or oval, mostly subcutaneous nodule made up chiefly of a mass of Aschoff bodies and seen in cases of rheumatic fever. It is differentiated from the RHEUMATOID NODULE which appears in rheumatoid arthritis, most frequently over bony prominences. (From Dorland, 27th ed)


Endoscopes for examining the interior of the esophagus.


Infection of the spleen with species of MYCOBACTERIUM.


The occurrence in an individual of two or more cell populations of different chromosomal constitutions, derived from a single ZYGOTE, as opposed to CHIMERISM in which the different cell populations are derived from more than one zygote.


Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.


Two-phase systems in which one is uniformly dispersed in another as particles small enough so they cannot be filtered or will not settle out. The dispersing or continuous phase or medium envelops the particles of the discontinuous phase. All three states of matter can form colloids among each other.


A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.


Enzymes of the isomerase class that catalyze reactions in which a group can be regarded as eliminated from one part of a molecule, leaving a double bond, while remaining covalently attached to the molecule. (From Enzyme Nomenclature, 1992) EC 5.5.


The cellular processes involved in adjustments to the MITOCHONDRIAL VOLUME, content, and activity, that depend on the energy demands of the cell.


Interactive Ventilatory Support
Proportional Assist Ventilation
Neurally Adjusted Ventilatory Assist

Delivery of ventilator support based on the patient's changing respiratory mechanics which vary at each breathing cycle.


Visible gaseous suspension of carbon and other particulate matter emitted from burning substances.


An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.


Phosphotransferases (Nitrogenous Group Acceptor)

A group of enzymes that catalyzes the transfer of a phosphate group onto a nitrogenous group acceptor. EC 2.7.3.


A species of gram-positive, coccoid bacteria that is numerous in the mouth and throat. It is a common cause of endocarditis and is also implicated in dental plaque formation.


The use of statistical and mathematical methods to analyze biological observations and phenomena.


Devices or tools used in combat or fighting in order to kill or incapacitate.


An enzyme that catalyzes the oxidation of protocatechuate to 3-carboxy-cis-cis-muconate in the presence of molecular oxygen. It contains ferric ion. EC 1.13.11.3.


A cardiac arrhythmia that is caused by interaction of two independently initiated cardiac impulses of different rates from two separate foci. Generally one focus is the SINOATRIAL NODE, the normal pacemaker. The ectopic focus is usually in the HEART VENTRICLE but can be in the HEART ATRIUM or the ATRIOVENTRICULAR NODE. Modulation of the parasystolic rhythm by the sinus rhythm depends on the completeness of entrance block surrounding the parasystolic focus.


A competitive nine-member team sport including softball.


A phylum of bacteria comprising four classes; Bacteroidia, Cytophagia, Flavobacteriia, and Sphingobacteriia.


Course of conduct directed at a specific person that involves repeated (two or more occasions) visual or physical proximity, nonconsensual communication, or verbal, written, or implied threats, or a combination thereof, that would cause a reasonable person fear.


A plant genus of the family ANNONACEAE. Members contain aporphines, acetogenins and rollinone.


A species of bacteria found in the marine environment, sea foods, and the feces of patients with acute enteritis.


Recruitment, Neurophysiological
Recruitment, Motor Unit

The spread of response if stimulation is prolonged. (Campbell's Psychiatric Dictionary, 8th ed.)


A plant family of the order Liliales, subclass Liliidae, class Liliopsida (monocotyledons). Most species are perennials, native primarily to tropical America. They have creeping rootstocks, fibrous roots, and leaves in clusters at the base of the plant or borne on branched stems. The fruit is a capsule containing many seeds, or a one-seeded winged structure.


The technique of placing cells or tissue in a supporting medium so that thin sections can be cut using a microtome. The medium can be paraffin wax (PARAFFIN EMBEDDING) or plastics (PLASTIC EMBEDDING) such as epoxy resins.


Tiazac
CRD-401
Cardil
Dilacor
Dilren
Diltiazem Hydrochloride
Diltiazem Malate
Cardizem
Dilacor XR
Diltiazem
Aldizem
Dilzem

A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.


A plant genus of the family RHAMNACEAE. Root nodules host the Frankia (ACTINOMYCETES) nitrogen-fixing bacteria.


Aesthetic surgical treatment of the abdominal region using LIPOSUCTION associated with ABDOMINOPLASTY.


Hallucinations, Olfactory
Hallucinations, Somatic
Hallucinations, Tactile
Hallucinations, Hypnagogic
Hallucinations, Elementary
Hallucinations
Hallucinations, Auditory
Hallucinations, Kinesthetic
Hallucinations, Verbal Auditory
Hallucinations, Mood Congruent
Hallucinations, Hypnapompic
Hallucinations, Organic
Hallucinations, Visual
Hallucinations, Sensory
Hallucinations, Dissociative
Hallucinations, Gustatory
Hallucinations, Mood Incongruent
Hallucination of Body Sensation
Hallucinations, Formed, of People
Hallucinations, Visual, Unformed
Hallucinations, Visual, Formed
Hallucinations, Reflex
Hallucinations, Internal Body Sensation

Subjectively experienced sensations in the absence of an appropriate stimulus, but which are regarded by the individual as real. They may be of organic origin or associated with MENTAL DISORDERS.


A sensory branch of the MANDIBULAR NERVE, which is part of the trigeminal (5th cranial) nerve. The lingual nerve carries general afferent fibers from the anterior two-thirds of the tongue, the floor of the mouth, and the mandibular gingivae.


A phase transition from liquid state to gas state, which is affected by Raoult's law. It can be accomplished by fractional distillation.


A human cell line established from a diffuse histiocytic lymphoma (HISTIOCYTIC LYMPHOMA, DIFFUSE) and displaying many monocytic characteristics. It serves as an in vitro model for MONOCYTE and MACROPHAGE differentiation.


Condition in which the plasma levels of homocysteine and related metabolites are elevated (>13.9 μmol/l). Hyperhomocysteinemia can be familial or acquired. Development of the acquired hyperhomocysteinemia is mostly associated with vitamins B and/or folate deficiency (e.g., PERNICIOUS ANEMIA, vitamin malabsorption). Familial hyperhomocysteinemia often results in a more severe elevation of total homocysteine and excretion into the urine, resulting in HOMOCYSTINURIA. Hyperhomocysteinemia is a risk factor for cardiovascular and neurodegenerative diseases, osteoporotic fractures and complications during pregnancy.


Cytoskeleton
Microtrabecular Lattice
Cytoplasmic Filaments
Cytoskeletal Filaments

The network of filaments, tubules, and interconnecting filamentous bridges which give shape, structure, and organization to the cytoplasm.


Six-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives. Various polyneuropathies are caused by hexane poisoning.


Berries
Fruit
Plant Aril
Plant Capsule
Legume Pod

The fleshy or dry ripened ovary of a plant, enclosing the seed or seeds.


A method, developed by Dr. Virginia Apgar, to evaluate a newborn's adjustment to extrauterine life. Five items - heart rate, respiratory effort, muscle tone, reflex irritability, and color - are evaluated 60 seconds after birth and again five minutes later on a scale from 0-2, 0 being the lowest, 2 being normal. The five numbers are added for the Apgar score. A score of 0-3 represents severe distress, 4-7 indicates moderate distress, and a score of 7-10 predicts an absence of difficulty in adjusting to extrauterine life.


Facilities which provide care for infants.


The reversibly oxidized form of ascorbic acid. It is the lactone of 2,3-DIKETOGULONIC ACID and has antiscorbutic activity in man on oral ingestion.


A pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. Significant attenuation of the cardiopulmonary changes are noted after oral magnesium treatment.


Measurable biological (physiological, biochemical, and anatomical features), behavioral (psychometric pattern) or cognitive markers that are found more often in individuals with a disease than in the general population. Because many endophenotypes are present before the disease onset and in individuals with heritable risk for disease such as unaffected family members, they can be used to help diagnose and search for causative genes.


A voluntary contract between two or more doctors who may or may not share responsibility for the care of patients, with proportional sharing of profits and losses.


Institutional Ethics Committees
Ethics Committees
Regional Ethics Committees

Committees established by professional societies, health facilities, or other institutions to consider decisions that have bioethical implications. The role of these committees may include consultation, education, mediation, and/or review of policies and practices. Committees that consider the ethical dimensions of patient care are ETHICS COMMITTEES, CLINICAL; committees established to protect the welfare of research subjects are ETHICS COMMITTEES, RESEARCH.


Stable xenon atoms that have the same atomic number as the element xenon, but differ in atomic weight. Xe-124, 126, 128-131, 134, and 136 are stable xenon isotopes.


A lymphatic disease characterized by INFLAMMATION of LYMPHATIC VESSELS.


An area occupying the most posterior aspect of the ABDOMINAL CAVITY. It is bounded laterally by the borders of the quadratus lumborum muscles and extends from the DIAPHRAGM to the brim of the true PELVIS, where it continues as the pelvic extraperitoneal space.


Communications via an interactive conference between two or more participants at different sites, using computer networks (COMPUTER COMMUNICATION NETWORKS) or other telecommunication links to transmit audio, video, and data.


A subclass of alpha-amylase ISOENZYMES that are secreted into PANCREATIC JUICE.


A species of gram-negative bacteria strongly implicated in oral infection, PERIODONTAL DISEASES, eye and ear disorders, and SEPTIC ARTHRITIS.


A microtubule-disrupting pre-emergence herbicide.


Proteins found in SEMEN. Major seminal plasma proteins are secretory proteins from the male sex accessory glands, such as the SEMINAL VESICLES and the PROSTATE. They include the seminal vesicle-specific antigen, an ejaculate clotting protein; and the PROSTATE-SPECIFIC ANTIGEN, a protease and an esterase.


An ULCER of the skin and underlying tissues.


Process of preserving a dead body to protect it from decay.


Form of radioimmunoassay in which excess specific labeled antibody is added directly to the test antigen being measured.


The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis.


The experimental joining of two individuals for the purpose of studying the effects of one on the other.


Viruses which produce a mottled appearance of the leaves of plants.


A group of toxic chemical compounds that share chemical structures and biological characteristics that are related to the potent carcinogen 2,3,7,8-tetrachlorodibenzo-p-dioxin.


A multisubunit polycomb protein complex that catalyzes the METHYLATION of chromosomal HISTONE H3. It works in conjunction with POLYCOMB REPRESSIVE COMPLEX 1 to effect EPIGENETIC REPRESSION.


A species in the ORTHOBUNYAVIRUS genus of the family BUNYAVIRIDAE family. Previously a large group of serotypes, most are now considered separate species.


A plant family of the order Cornales, subclass Rosidae, class Magnoliopsida, consisting of slow-growing evergreen trees common in tropical forests of south India and Burma. Members contain tetrahydroisoquinoline-monoterpene and iridoid glycosides.


A colorless liquid used as a solvent and an antiseptic. It is one of the ketone bodies produced during ketoacidosis.


A genus of gram-negative, aerobic bacteria that causes BRUCELLOSIS. Its cells are nonmotile coccobacilli and are animal parasites and pathogens. The bacterium is transmissible to humans through contact with infected dairy products or tissue.


Computer processing of a language with rules that reflect and describe current usage rather than prescribed usage.


Ecological Parameter Monitoring
Ecosystem Health Monitoring

Measuring and analysing the data from various biochemical or physiochemical indicators that reflect the condition of an ECOSYSTEM.


The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.


A genus of gram-negative, facultatively anaerobic bacteria including species which are often associated with grasses (POACEAE) and which fix nitrogen as well as species which anaerobically degrade toluene and other mono-aromatic hydrocarbons.


A genus of gram-negative organisms including saprophytic and parasitic or pathogenic species.


An act which constitutes the termination of a given instinctive behavior pattern or sequence.


A plant genus of the family LAMIACEAE best known for the thyme spice added to foods.


Body Representation
Body Schema
Body Image

Individual's non-conscious representation of their bodies that regulates posture and movement.


An infectious disease of the skin caused by Treponema carateum that occurs only in the western hemisphere. Age of onset is between 10 and 20 years of age. This condition is characterized by marked changes in the skin color and is believed to be transmitted by direct person-to-person contact.


Disciplines concerned with the interrelationships of individuals in a social environment including social organizations and institutions. Includes Sociology and Anthropology.


Repetitive visual hallucinations experienced mostly by elderly with diminished visual acuity or visual field loss, with awareness of the fictional nature of their hallucinations. It is not associated with delusions and other sensory hallucinations.


Destinations frequented as vacation or recreational retreats, equipped with specialized amenities, treatments and facilities, for the promotion of general well-being and health.


Inflammation of the mouth due to denture irritation.


Cyclohexanes which contain two double bonds in the ring.


A genus of coccidian parasites in the family EIMERIIDAE. Cyclospora cayetanensis is pathogenic in humans, probably transmitted via the fecal-oral route, and causes nausea and diarrhea.


A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.


The yam plant family, of the order Liliales, has thick roots or tubers and net-veined, heart-shaped leaves that sometimes are lobed.


Individual's expression of desirability or value of one course of action, outcome, or selection in contrast to others.


The process that starts the transcription of an RNA molecule. It includes the assembly of the initiation complex and establishment of the start site.


A computer disk read by a laser beam, containing data prerecorded by a vendor. The buyer cannot enter or modify data in any way but the advantages lie in the speed of accessibility, relative immunity to damage, and relatively low cost of purchase.


Infusions, Intracerebroventricular
Infusions, Intraventricular

Delivery of drugs into the ventricular system of brain.


A family of bacteria which produce endospores. They are mostly saprophytes from soil, but a few are insect or animal parasites or pathogens.


The various physical methods which include wind, insects, animals, tension, and water, by which a plant scatters its seeds away from the parent plant.


A species of gram-negative, rod-shaped bacteria isolated from the intestinal tract of swine, poultry, and man. It may be pathogenic.


Diseases that occur in PREMATURE INFANTS.


The numerous (6-12) small thin-walled spaces or air cells in the ETHMOID BONE located between the eyes. These air cells form an ethmoidal labyrinth.


Articles of food which are derived by a process of manufacture from any portion of carcasses of any animal used for food (e.g., head cheese, sausage, scrapple).


A mitosporic Saccharomycetales fungal genus, various species of which have been isolated from pulmonary lesions. Teleomorphs include Dipodascus and Galactomyces.


A thrombin-like enzyme from the venom of snakes of the viper/rattlesnake group. Species variants of the enzyme include ANCROD (Agkistrodon rhodostoma (Malayan pit viper)); BATROXOBIN from Bothrops atrox; and crotalase from Crotalus adamanteus (Eastern diamondback rattlesnake). EC 3.4.21.74.


The hospital unit in which patients with respiratory conditions requiring special attention receive intensive medical care and surveillance.


A member of the epidermal growth factor (EGF) family of peptide growth factors that is synthesized as a transmembrane protein which can be cleaved to release a soluble active form. Epiregulin has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR.


Studies of interactions between living organisms and characteristics of the extraterrestrial environment. These studies specifically address the structure and function of living organisms in an extraterrestrial environment and interdependent relationships of organisms with each other and/or the extraterrestrial environment while also touching on the origin, evolution and potential for extraterrestrial life. (From www.nasa.gov/audience/foreducators/spacelife/)


The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for, among other things, VIRUS CULTIVATION and PRECLINICAL DRUG EVALUATION assays.


Inflammation of the vagina due to thinning of the vaginal wall and decreased lubrication associated with reduced estrogen levels at MENOPAUSE.


A measurement of collective behavior and attitudes that exist towards a specific person—a measurement of the social environment or social relationships of an individual.


Apoptotic Bodies
Exovesicles
Extracellular Vesicles

Extracellular vesicles released from fragmenting apoptotic cells.


Polyviol
Liquifilm Tears
Polyvinyl Alcohol

A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.


A low molecular weight peptide of about 800-1000 having a negative inotropic effect. It is released into the circulation during experimental hemorrhagic pancreatitis, severe ischemia, and postoligemic shock.


Proteins obtained from species of fish (FISHES).


Removal of an implanted therapeutic or prosthetic device.


Tenotomy
Tendon Release
Heel-Cord Release
Tendon Lengthening

Surgical division of a tendon for relief of a deformity that is caused by congenital or acquired shortening of a muscle (Stedman, 27th ed). Tenotomy is performed in order to lengthen a muscle that has developed improperly, or become shortened and is resistant to stretching.


Characteristics or attributes of the outer boundaries of objects, including molecules.


The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.


A cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a precursor for the biosynthesis of UBIQUINONE and the AROMATIC AMINO ACIDS.


Stable mercury atoms that have the same atomic number as the element mercury, but differ in atomic weight. Hg-196, 198-201, and 204 are stable mercury isotopes.


A genus of extremely halophilic HALOBACTERIACEAE which are chemoheterotropic and strictly aerobic. They are found in neutral saline environments such as salt lakes (especially the Dead Sea) and marine salterns.


A scale that assesses the outcome of serious craniocerebral injuries, based on the level of regained social functioning.


A genus of rod-shaped, oval, or bean-shaped bacteria found in soil and fresh water. Polar prosthecae are present and cells reproduce by budding at the tips of the prosthecae. Cells of this genus are aerobic and grow best with one-carbon compounds. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).


A widely cultivated plant, native to Asia, having succulent, edible leaves eaten as a vegetable. (From American Heritage Dictionary, 1982)


Moving towards a possibly rewarding stimulus or situation.


The total area or space visible in a person's peripheral vision with the eye looking straightforward.


A class of water-soluble polyelectrolytes with pi-delocalized structure and functional ionic properties used for fluorescent staining of cells and as semi-conducting materials in electronic devices.


Written, witnessed declarations in which persons request that if they become disabled beyond reasonable expectation of recovery, they be allowed to die rather than be kept alive by extraordinary means. (Bioethics Thesaurus)


Estrone, (+-)-Isomer
Estrone, (8 alpha)-Isomer
Estrone, (9 beta)-Isomer
Kestrone
Estrovarin
Folliculin
Wehgen
Estrone
Unigen

An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.


Polysaccharides consisting of xylose units.


A complex of several closely related glycosidic antibiotics from Streptomyces griseus. The major component, CHROMOMYCIN A3, is used as a fluorescent stain of DNA where it attaches and inhibits RNA synthesis. It is also used as an antineoplastic agent, especially for solid tumors.


Production of an image when x-rays strike a fluorescent screen.


Two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. (From Kandel, Schwartz, and Jessel, Principles of Neural Science, 3d ed, p766)


A rapid-growing, nonphotochromogenic species that is potentially pathogenic, producing lesions of lung, bone, or soft tissue following trauma. It has been found in soil and in injection sites of humans, cattle, and cold-blooded animals. (Dorland, 28th ed)


A skin crease on each side of the face that runs from the outer corners of the nose to the corner of the mouth. It is a common site of PLASTIC SURGERY.


A plant genus of the family VALERIANACEAE. Members contain ursolic acid and oleanolic acid glycosides, sulfapatrinosides (triterpenoid glycosides), and patriscabrol (iridolactone).


Nexium
Esomeprazole Magnesium
Esomeprazole Sodium
Esomeprazole
Esomeprazole Potassium
Esomeprazole Strontium
Esomeprazole Strontium Anhydrous


Rapid handwriting using simple strokes, abbreviations, or symbols that designate letters, words, or phrases.


An in vitro test used in the diagnosis of allergies including drug hypersensitivity. The allergen is added to the patient's white blood cells and the subsequent histamine release is measured.


Tendency toward involvement in accidents. Implies certain personality characteristics which predispose to accidents.


A measure of the functional capabilities of the heart, lungs and muscles, relative to the demands of specific exercise routines such as running or cycling.


A plant genus of the family CUCURBITACEAE. It is a source of gypenosides and triterpenoid SAPONINS.


A powerful synthetic, non-steroidal estrogen.


Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.


Nitrous acid (HNO2). A weak acid that exists only in solution. It can form water-soluble nitrites and stable esters. (From Merck Index, 11th ed)


The training or molding of an individual through various relationships, educational agencies, and social controls, which enables him to become a member of a particular society.


The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls.


Order of CHLOROPHYTA commonly found in freshwater habitats. Characteristics include the presence of a cellulose wall and two to four equal, smooth, apical flagella.


Techniques used for measuring BLOOD PRESSURE.


A disorder in which fantasies about or the act of exposing the genitals to an unsuspecting stranger produces sexual excitement with no attempt at further sexual activity with the stranger.


The possession of four chromosomes of any one type in an otherwise diploid cell.


A medical specialty concerned with the provision of continuing, comprehensive primary health care for the entire family.


A massive slaughter, especially the systematic mass extermination of European Jews in Nazi concentration camps prior to and during World War II.


The full set of CHROMOSOMES presented as a systematized array of METAPHASE chromosomes from a photomicrograph of a single CELL NUCLEUS arranged in pairs in descending order of size and according to the position of the CENTROMERE. (From Stedman, 25th ed)


Brain waves seen on EEG characterized by a high amplitude and a frequency of 4 Hz and below. They are considered the "deep sleep waves" observed during sleep in dreamless states, infancy, and in some brain disorders.


A genus of gram-positive bacteria in the family Listeriaceae. It has 93% homology to LISTERIA and shares with it many phenotypic properties.


Compounds based on 2-amino-4-hydroxypteridine.


Substances obtained from various species of microorganisms that are, alone or in combination with other agents, of use in treating various forms of tuberculosis; most of these agents are merely bacteriostatic, induce resistance in the organisms, and may be toxic.


A man-made radioactive actinide with atomic symbol Es, and atomic number 99. Its known isotopes range in mass number from 240-258. Its valence can be +2 or +3. Einsteinium was originally discovered in the debris from a thermonuclear explosion in 1952.


The use of automatic machines or processing devices in libraries. The automation may be applied to library administrative activities, office procedures, and delivery of library services to users.


A genus of the family POXVIRIDAE, subfamily CHORDOPOXVIRINAE, consisting of ether-sensitive viruses of leporids and squirrels. They commonly cause tumors and are usually transmitted mechanically by arthropods. MYXOMA VIRUS is the type species.


Various components of food that are required for nourishment.


A large and diverse group in the order CAMPYLOBACTERALES, individual species of which grow in aerobic and anaerobic conditions as free-living, commensal, or pathogenic forms.


Antioxidant for foods, fats, oils, ethers, emulsions, waxes, and transformer oils.


A modification of the freeze-drying method in which the ice within the frozen tissue is replaced by alcohol or other solvent at a very low temperature.


A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.


Abbreviations as Topic
Acronyms as Topic

Works about shortened forms of written words or phrases used for brevity.


The process of repairing broken or worn parts of a PERMANENT DENTAL RESTORATION.


A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.


A plant genus of the family ANACARDIACEAE that is the source of anacarcin forte. The nut milk extract is cytotoxic.


Pathological processes involving the URETHRA.


The teaching ascribed to Gautama Buddha (ca. 483 B.C.) holding that suffering is inherent in life and that one can escape it into nirvana by mental and moral self-purification. (Webster, 3d ed)


Eighteen-carbon essential fatty acids that contain three double bonds.


A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.


Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.


Excision of one or both adrenal glands. (From Dorland, 28th ed)


Excision of the adenoids. (Dorland, 28th ed)


The aglycone constituents of CARDIAC GLYCOSIDES. The ring structure is basically a cyclopentanoperhydrophenanthrene nucleus attached to a lactone ring at the C-17 position.


A vitamin antagonist which has teratogenic effects.


Inorganic and organic derivatives of sulfuric acid (H2SO4). The salts and esters of sulfuric acid are known as SULFATES and SULFURIC ACID ESTERS respectively.


Literature Based Discovery
Knowledge Discovery

A process that searches for hidden and important connections among information embedded in published literature.


An element of the rare earth family of metals. It has the atomic symbol Nd, atomic number 60, and atomic weight 144.24, and is used in industrial applications.


Toxins closely associated with the living cytoplasm or cell wall of certain microorganisms, which do not readily diffuse into the culture medium, but are released upon lysis of the cells.


The use of one's knowledge in a particular profession. It includes, in the case of the field of biomedicine, professional activities related to health care and the actual performance of the duties related to the provision of health care.


A genus of parasitic nematodes found in the digestive tract of herbivorous animals. They cause incidental infections in humans from the following species: Trichostrongylus colubriformis, T. orientalis, T. axei, and T. probolurus.


Family Size, Completed
Generations
Family Size, Desired
Family Size, Ideal
Family Size, Average
Family Size
Family Demography
Patriarchy
Family Life Surveys
Family and Household
Head of Household
Matriarchy
Couples
Households
Family Size, Expected
Family Characteristics
One-Person Household


Rice tungro spherical virus
Anthriscus yellow virus
Waikavirus
Maize chlorotic dwarf virus

A genus of plant viruses in the family SEQUIVIRIDAE. Transmission is by leafhoppers or APHIDS and depends on a self-encoded helper protein. The type species is Rice tungro spherical virus.


Phytophthora cinnamomi
Phytophthora parasitica
Phytophthora ramorum
Phytophthora
Phytophthora sojae

A genus of destructive parasitic OOMYCETES in the family Peronosporaceae, order Peronosporales, affecting numerous fruit, vegetable, and other crops. Differentiation of zoospores usually takes place in the sporangium and no vesicle is formed. It was previously considered a fungus.


Mathematical procedure that transforms a number of possibly correlated variables into a smaller number of uncorrelated variables called principal components.


A plant genus in the LAURACEAE family. The bark of the trees is used in FOLK MEDICINE and FLAVORING AGENTS.


A masticatory muscle whose action is closing the jaws; its posterior portion retracts the mandible.


A LEUCINE and DNA-binding protein that is found primarily in BACTERIA and ARCHAEA. It regulates GENETIC TRANSCRIPTION involved in METABOLISM of AMINO ACIDS in response to the increased concentration of LEUCINE.


Oxides of a ring compound having atoms other than carbon in its ring.


An order of wholly aquatic MAMMALS occurring in all the OCEANS and adjoining seas of the world, as well as in certain river systems. They feed generally on FISHES, cephalopods, and crustaceans. Most are gregarious and most have a relatively long period of parental care and maturation. Included are DOLPHINS; PORPOISES; and WHALES. (From Walker's Mammals of the World, 5th ed, pp969-70)


The direct struggle between individuals for environmental necessities or for a common goal.


Softening and degeneration of the CARTILAGE.


Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.


Those physicians who have completed the education requirements specified by the American Academy of Family Physicians.


Behavioral response associated with the achieving of gratification.


An idiopathic syndrome characterized by the formation of granulation tissue in the anterior cavernous sinus or superior orbital fissure, producing a painful ophthalmoplegia. (Adams et al., Principles of Neurology, 6th ed, p271)


A continuing periodic change in displacement with respect to a fixed reference. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)


Transtympanic Micropressure Treatment
Meniett Therapy
Tympanic Membrane Massage

The use of a tympanic membrane massage device which is designed to deliver intermittent pressure to the middle ear.


A species of thermophilic, gram-positive bacteria found in MILK and milk products.


A rare, benign, inflammatory breast disease occurring in premenopausal women shortly after a recent pregnancy. The origin is unknown but it is commonly mistaken for malignancy and sometimes associated with BREAST FEEDING and the use of ORAL CONTRACEPTIVES.


Viscous materials composed of complex, high-molecular-weight compounds derived from the distillation of petroleum or the destructive distillation of wood or coal. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


Plant steroids ubiquitously distributed throughout the plant kingdom. They play essential roles in modulating growth and differentiation of cells at nanomolar to micromolar concentrations.


A genus of ascomycetous fungi in the family Trichocomaceae, order EUROTIALES. Health effects, allergenicity, and toxicity of Eurotium are closely related to its anamorph ASPERGILLUS.


Squamous Intraepithelial Lesions of the Cervix

A cytological test finding often from PAP SMEARS that shows abnormal lesions of SQUAMOUS EPITHELIAL CELLS of the CERVIX. It is a diagnostic criterion used in the Bethesda System for UTERINE CERVICAL NEOPLASMS and represents the PAP TEST result that is abnormal. Although squamous intraepithelial lesions test result does not mean UTERINE CERVICAL NEOPLASMS it requires follow-ups (e.g., HPV DNA TESTS; and COLPOSCOPY).


Qualified nursing professionals specializing in care of newborn infants.


A species of gram-negative bacteria that causes rickettsialpox. The vector is a mouse mite and the reservoirs are mites and mice.


Substances produced from the reaction between acids and bases; compounds consisting of a metal (positive) and nonmetal (negative) radical. (Grant & Hackh's Chemical Dictionary, 5th ed)


Polymers of high molecular weight which at some stage are capable of being molded and then harden to form useful components.


Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole rings. Protoporphyrin IX occurs in hemoglobin, myoglobin, and most of the cytochromes.


A group of elongate elasmobranchs. Sharks are mostly marine fish, with certain species large and voracious.


Food products manufactured from poultry.


The controlling of access to health services, usually by primary care providers; often used in managed care settings to reduce utilization of expensive services and reduce referrals. (From BIOETHICS Thesaurus, 1999)


Inflammation of any segment of the ILEUM and the ILEOCECAL VALVE.


A species of gram-negative bacteria originally isolated from the LUNGS; TRACHEA; and NASAL CAVITY of SHEEP. It causes chronic interstitial pneumonia (PNEUMONIA, MYCOPLASMA) in both SHEEP and GOATS.


6,17-Dimethylpregna-4,6-diene-3,20-dione. A synthetic progestational hormone with actions similar to those of progesterone. It is used in the treatment of menstrual irregularities and has also been employed in the treatment of prostatic hypertrophy and endometrial carcinoma.


Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation.


Works on the art and science of designing buildings and structures, design of the total built environment, including town planning, urban design, and landscape architecture.


A competitive sport played with a bat and ball between two teams of eleven players.


The infiltrating of tissue specimens with paraffin, as a supporting substance, to prepare for sectioning with a microtome.


Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.


Characteristic restricted to a particular organ of the body, such as a cell type, metabolic response or expression of a particular protein or antigen.


Measurement of blood flow based on induction at one point of the circulation of a known change in the intravascular heat content of flowing blood and detection of the resultant change in temperature at a point downstream.


Physical Conditioning, Human
Physical Training, Human

Diet modification and physical exercise to improve the ability to carry out daily tasks and perform physical activities.


Sesuvium Tetragonia Aizoaceae Trianthema

A plant family of the order Caryophyllales, subclass Caryophyllidae, class Magnoliopsida.


Paired, segmented masses of MESENCHYME located on either side of the developing spinal cord (neural tube). Somites derive from PARAXIAL MESODERM and continue to increase in number during ORGANOGENESIS. Somites give rise to SKELETON (sclerotome); MUSCLES (myotome); and DERMIS (dermatome).


A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.


Prolonged separation of the offspring from the father.


Power Plants
Electric Power Plants
Thermoelectric Power Plants
Hydroelectric Power Plants

Units that convert some other form of energy into electrical energy.


A family of extremely halophilic archaea found in environments with high salt concentrations, such as salt lakes, evaporated brines, or salted fish. Halobacteriaceae are either obligate aerobes or facultative anaerobes and are divided into at least twenty-six genera including: HALOARCULA; HALOBACTERIUM; HALOCOCCUS; HALOFERAX; HALORUBRUM; NATRONOBACTERIUM; and NATRONOCOCCUS.


Histological Labeling
Staining
Staining and Labeling

The use of a dye, reagent, or other material for producing coloration or contrast in biological materials for examination or observation.


One of several skin tests to determine past or present tuberculosis infection. A purified protein derivative of the tubercle bacilli, called tuberculin, is introduced into the skin by scratch, puncture, or interdermal injection.


A group of antigens consisting principally of Jk(a) and Jk(b), determined by allelic genes. Amorphs are encountered. Antibodies of these substances are usually weak and quite labile, stimulated by erythrocytes.


Works about critical analyses of books or other monographic works.


Azomonas
Pseudomonadaceae
Azotobacteraceae
Azomonas agilis

A subfamily of motile, gram-negative bacteria found in SOIL and WATER and capable of fixing atmospheric nitrogen.


A genus of intestinal nematode parasites belonging to the superfamily HELIGMOSOMATOIDEA, which commonly occurs in rats but has been experimentally transmitted to other rodents and rabbits. Infection is usually through the skin.


The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds.


Congenital Varicella Syndrome
Varicella Zoster Virus Infection

Infection caused by HUMAN HERPES VIRUS 3 (e.g., CHICKENPOX and HERPES ZOSTER).


A form species of spore-producing CYANOBACTERIA, in the family Nostocaceae, order Nostocales. It is an important source of fixed NITROGEN in nutrient-depleted soils. When wet, it appears as a jelly-like mass.


Lower urinary tract symptom, such as slow urinary stream, associated with PROSTATIC HYPERPLASIA in older men.


Human papillomavirus 4
Human papillomavirus 60
Gammapapillomavirus

A genus of DNA viruses in the family PAPILLOMAVIRIDAE, which cause cutaneous lesions in humans. They are histologically distinguishable by intracytoplasmic INCLUSION BODIES which are species specific.


The flow of BLOOD through or around an organ or region of the body.


A plant genus of the family APIACEAE. Members contain COUMARINS.


Conduct and synthesis of systematic research comparing interventions and strategies to prevent, diagnose, treat, and monitor health conditions. The purpose of this research is to inform patients, providers, and decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances. (hhs.gov/recovery/programs/cer/draftdefinition.html accessed 6/12/2009)


The restoration to life or consciousness of one apparently dead. (Dorland, 27th ed)


Proteins that are chemically bound to a substrate material which renders their location fixed. The immobilization of proteins allows their use in chemical reactions without being diluted by solvent.


Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.


Formation of an acetyl derivative. (Stedman, 25th ed)


The series of cells in the red blood cell lineage at various stages of differentiation.


A species of CAMPYLOBACTER comprised of three biovars based on their reaction to CATALASE and UREASE. They have been isolated from humans, CATTLE, and SHEEP.


Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.


An enzyme that catalyzes the hydrolysis of allophanic acid to two molecules of ammonia plus two molecules of "active carbon dioxide". EC 3.5.1.54.


A plant genus of the family LYCOPODIACEAE. Members contain ALKALOIDS. Lycopodium oil is obtained from L. clavatum.


A humanized monoclonal immunoglobulin G4 antibody to human INTEGRIN ALPHA4 that binds to the alpha4 subunit of INTEGRIN ALPHA4BETA1 and integrin alpha4beta7. It is used as an IMMUNOLOGIC FACTOR in the treatment of RELAPSING-REMITTING MULTIPLE SCLEROSIS and CROHN'S DISEASE.


Pathological processes of the ADRENAL CORTEX.


A system of artificial or natural drains, generally used for the disposal of liquid wastes.


A derivative of benzodiazepine that acts on the cholecystokinin A (CCKA) receptor to antagonize CCK-8's (SINCALIDE) physiological and behavioral effects, such as pancreatic stimulation and inhibition of feeding.


Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.


Generating, planning, organizing, and administering medical and nursing care and services for patients.


A sheet of fibrous connective tissue rich in COLLAGEN often linking two parallel bony structures forming a syndesmosis type joint. It provides longitudinal stability, TENSILE STRENGTH, and weight distribution/transfer and may allow limited movement in syndesmoses.


A plant genus of the family CARYOPHYLLACEAE. The common name "Soapwort" is also used with SAPONARIA.


Cyclic heptapeptides found in MICROCYSTIS and other CYANOBACTERIA. Hepatotoxic and carcinogenic effects have been noted. They are sometimes called cyanotoxins, which should not be confused with chemicals containing a cyano group (CN) which are toxic.


A rare developmental defect in which the heart is abnormally located partially or totally outside the THORAX. It is the result of defective fusion of the anterior chest wall. Depending on the location of the heart, ectopia cordis can be thoracic, thoracoabdominal, abdominal, and cervical.


A dimension of auditory sensation varying with cycles per second of the sound stimulus.


The deferment of actions or tasks to a later time, or to infinity.


Betapolyomavirus Polyomaviridae Gammapolyomavirus Deltapolyomavirus Alphapolyomavirus

A family of small, non-enveloped DNA viruses, infecting mainly MAMMALS.


A genus in the family PICORNAVIRIDAE causing upper respiratory disease in horses.


The release of ideas, thoughts, and repressed material from the unconscious, accompanied by an emotional response and relief. (From Dorland, 28th ed)


Pleasure derived from being physically or psychologically abused, whether inflicted by oneself or by others. Masochism includes sexual masochism.


A genus of gram-positive aerobic cocci found in the soil, that is highly resistant to radiation, especially ionizing radiation (RADIATION, IONIZING). Deinococcus radiodurans is the type species.


A rod-shaped to ellipsoidal, gram-negative bacterium which oxidizes ethanol to acetic acid and prefers sugar-enriched environments. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


Respiratory failure in the newborn. (Dorland, 27th ed)


High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages.


Organic compounds that contain GOLD as an integral part of the molecule. Some are used as ANTIRHEUMATIC AGENTS. The term chrysotherapy derives from an ancient Greek term for gold.


Factors associated with the definitive onset of a disease, illness, accident, behavioral response, or course of action. Usually one factor is more important or more obviously recognizable than others, if several are involved, and one may often be regarded as "necessary". Examples include exposure to specific disease; amount or level of an infectious organism, drug, or noxious agent, etc.


Proenzymes secreted by chief cells, mucous neck cells, and pyloric gland cells, which are converted into pepsin in the presence of gastric acid or pepsin itself. (Dorland, 28th ed) In humans there are 2 related pepsinogen systems: PEPSINOGEN A (formerly pepsinogen I or pepsinogen) and PEPSINOGEN C (formerly pepsinogen II or progastricsin). Pepsinogen B is the name of a pepsinogen from pigs.


The main artery of the thigh, a continuation of the external iliac artery.


The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.


Comprehensive Health Plans, Local
Health Systems Plans

Statements of goals for the delivery of health services pertaining to the Health Systems Agency service area, established under PL 93-641, and consistent with national guidelines for health planning.


Paired but separate cavity within the THORACIC CAVITY. It consists of the space between the parietal and visceral PLEURA and normally contains a capillary layer of serous fluid that lubricates the pleural surfaces.


Miracil D
Lucanthone
Lucanthone Hydrochloride
Tixantone

One of the SCHISTOSOMICIDES, it has been replaced largely by HYCANTHONE and more recently PRAZIQUANTEL. (From Martindale The Extrapharmacopoeia, 30th ed., p46)


Absence of crystalline lens totally or partially from field of vision, from any cause except after cataract extraction. Aphakia is mainly congenital or as result of LENS DISLOCATION AND SUBLUXATION.


Symptom characterized by the passage of stool once a week or less.


Organizations such as (1) congregations; (2) national networks, which include national denominations, their social service arms (for example, Catholic Charities, Lutheran Social Services), and networks of related organizations (such as YMCA and YWCA); and (3) freestanding religious organizations, which are incorporated separately from congregations and national networks. http://www.huduser.gov/portal/publications/faithbased.pdf


A branch of embryology for the study of congenital malformations and developmental abnormalities.


A chronic skin disease characterized by small follicular papules, disseminated reddish-brown scaly patches, and often, palmoplantar hyperkeratosis. The papules are about the size of a pin and topped by a horny plug.


Half-Sib Mating
Genetic Inbreeding
Inbreeding
Sib Mating
Backcrossing

The mating of plants or non-human animals which are closely related genetically.


A genus of protozoa of the suborder BLASTOCYSTINA. It was first classified as a yeast but further studies have shown it to be a protozoan.


Equipment used to prevent contamination of and by patients, especially those with bacterial infections. This includes plastic surgical isolators and isolators used to protect immunocompromised patients.


Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.


Order in class ALPHAPROTEOBACTERIA that are endosymbionts in eukaryotic cells. High morbidity and mortality are frequently associated with Rickettsiales transmitted by INSECT VECTORS.


Inorganic compounds that contain magnesium as an integral part of the molecule.


A plant family of the order Ranunculales, subclass Magnoliidae, class Magnoliopsida. Members are mostly vines and shrubs and they contain isoquinoline alkaloids, some of which have been used as arrow poisons.


A colorless compound formed in the intestines by the reduction of bilirubin. Some is excreted in the feces where it is oxidized to urobilin. Some is reabsorbed and re-excreted in the bile as bilirubin. At times, it is re-excreted in the urine, where it may be later oxidized to urobilin.


Genetic disorders caused by defects in genes related to the primary CILIUM; BASAL BODY; or CENTROSOME. Primary features may include obesity, SKELETAL DYSPLASIA; POLYDACTYLY and malformations that primarily involve the liver, eye or kidneys.


The discipline pertaining to the study of animal behavior.


A process through which individuals encode information about their environmental CUES to facilitate SPATIAL NAVIGATION.


Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition.


A non-tuberculous mycobacterium causing cervical lymphadenitis in children. It very rarely causes pulmonary disease, and is believed to be non-pathogenic in animals.


Any chemical species which acts as an electron-pair donor in a chemical bonding reaction with a LEWIS ACID.


A form-genus of unicellular coccoid to rod-shaped CYANOBACTERIA, in the order Chroococcales. Three different clusters of strains from diverse habitats are included.


A live attenuated virus vaccine of duck embryo or human diploid cell tissue culture origin, used for routine immunization of children and for immunization of nonpregnant adolescent and adult females of childbearing age who are unimmunized and do not have serum antibodies to rubella. Children are usually immunized with measles-mumps-rubella combination vaccine. (Dorland, 28th ed)


A genus of mitosporic fungi containing about 100 species and eleven different teleomorphs in the family Trichocomaceae.


A blue-red, extremely painful vascular neoplasm involving a glomeriform arteriovenous anastomosis (glomus body), which may be found anywhere in the skin, most often in the distal portion of the fingers and toes, especially beneath the nail. It is composed of specialized pericytes (sometimes termed glomus cells), usually in single encapsulated nodular masses which may be several millimeters in diameter (From Stedman, 27th ed). CHEMODECTOMA, a tumor of NEURAL CREST origin, is also sometimes called a glomus tumor.


Activities devoted to freeing persons or animals from danger to life or well-being in accidents, fires, bombings, floods, earthquakes, other disasters and life-threatening conditions. While usually performed by team efforts, rescue work is not restricted to organized services.


An order of gram-positive bacteria in the class Bacilli, phylum Firmicutes.


An international professional organization composed of one association per country for the purpose of improving and developing nursing's contribution to the promotion of health and care of the sick.


Organic compounds composed of tin and three ethyl groups. Affect mitochondrial metabolism and inhibit oxidative phosphorylation by acting directly on the energy conserving processes.


Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.


Permanent deprivation of breast milk and commencement of nourishment with other food. (From Stedman, 25th ed)


A plant family of the order Celastrales, subclass Rosidae, class Magnoliopsida, a small family growing in the tropics. Members contain piperidine alkaloids and GLUCOSINOLATES.


Occurrence or induction of ESTRUS in all of the females in a group at the same time, applies only to non-primate mammals with ESTROUS CYCLE.


The parts of a transcript of a split GENE remaining after the INTRONS are removed. They are spliced together to become a MESSENGER RNA or other functional RNA.


Spontaneous Combustion
Preternatural Human Combustibility

A circumstance where a substance or organism takes fire and burns without an exogenous source. Spontaneous human combustion differs from preternatural human combustibility in that in the latter, some spark or trivial flame sets the fire and the body tissues, which have a greatly enhanced inflammability, continue to undergo incineration without any external heat source or combustible materials. (Bergman NA. Spontaneous human combustion: its role in literature and science. Pharos 1988;Fall;51(4):18-21)


A species of gram-negative bacteria isolated from the SYNOVIAL FLUID; LYMPH NODES; and MUCOUS MEMBRANE secretions in diseased SWINE. It causes nonsuppurative ARTHRITIS.


A thin-walled distention of the alimentary tract protruding just outside the body cavity in the distal end of the neck (esophagus), used for the temporary storage of food and water.


The specialties in psychiatry and psychology, their diagnostic techniques and tests, their therapeutic methods, and psychiatric and psychological services.


Overlapping of cloned or sequenced DNA to construct a continuous region of a gene, chromosome or genome.


Ozone Depletion
Ozone Hole
Ozone Layer Depletion

A large area over a region of the Earth in the OZONE LAYER where OZONE destruction has overtaken ozone production.


A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.


A seven-membered aromatic ring compound. It is structurally related to a number of naturally occurring antifungal compounds (ANTIFUNGAL AGENTS).


The study, control, and application of the conduction of ELECTRICITY through gases or vacuum, or through semiconducting or conducting materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)


Compounds based on 5,6,7,8-tetrahydrofolate.


A condition in which the FORESKIN cannot be retracted to reveal the GLANS PENIS. It is due to tightness or narrowing of the foreskin opening.


The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.


A species of extremely thermophilic, sulfur-reducing archaea. It grows at a maximum temperature of 95 degrees C. in marine or deep-sea geothermal areas.


Conditioning to defecate and urinate in culturally acceptable places.


The passive movement of molecules exceeding the rate expected by simple diffusion. No energy is expended in the process. It is achieved by the introduction of passively diffusing molecules to an enviroment or path that is more favorable to the movement of those molecules. Examples of facilitated diffusion are passive transport of hydrophilic substances across a lipid membrane through hydrophilic pores that traverse the membrane, and the sliding of a DNA BINDING PROTEIN along a strand of DNA.


A plant family of the order Capparales, subclass Dilleniidae, class Magnoliopsida. It is a small family of herbs and shrubs. Some produce GLUCOSINOLATES.


Wharton's Duct
Stensen's Duct
Salivary Ducts

Any of the ducts which transport saliva. Salivary ducts include the parotid duct, the major and minor sublingual ducts, and the submandibular duct.


An order of CRENARCHAEOTA consisting of aerobic or facultatively aerobic, chemolithotrophic cocci which are extreme thermoacidophiles. They lack peptidoglycan in their cell walls.


A plant genus, of the family ONAGRACEAE, which is the subject of genetic studies. The floral aroma is attributed to benzenoid esters and benzyl acetate.


Volume of circulating blood in a region of the brain. It is a functional measure of the brain perfusion status which relates changes in this to changes in CEREBROVASULAR CIRCULATION that are often seen in brain diseases.


Argonaute Proteins
Ago Subfamily of Argonaute Proteins
PIWI Subfamily of Argonaute Proteins

A subfamily of argonaute proteins that are related to the Arabidopsis AGO1 protein.


Break or rupture of a tooth or tooth root.


The systematic study of how genetic information or GENOMICS translates into biochemical, metabolic and morphological traits of an organism.


Infections caused by bacteria and fungi, general, specified, or unspecified.


Semi-synthetic complex derived from nucleic-acid free viral particles. They are essentially reconstituted viral coats, where the infectious nucleocapsid is replaced by a compound of choice. Virosomes retain their fusogenic activity and thus deliver the incorporated compound (antigens, drugs, genes) inside the target cell. They can be used for vaccines (VACCINES, VIROSOME), drug delivery, or gene transfer.


The administration of medication or fluid directly into localized lesions, by means of gravity flow or INFUSION PUMPS.


Terminology as Topic
Nomenclature as Topic
Etymology

Works about the terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.


An early embryo that is a compact mass of about 16 BLASTOMERES. It resembles a cluster of mulberries with two types of cells, outer cells and inner cells. Morula is the stage before BLASTULA in non-mammalian animals or a BLASTOCYST in mammals.


A plant genus of the family FABACEAE. The common name of "Bird-Of-Paradise" is also used for other plants such as Heliconia (HELICONIACEAE) and Strelitzia (STRELITZIACEAE) and some birds. The common name of "Cat's-Claw" is more often used with UNCARIA. The common name of "Pernambuco" also refers to a state in Brazil. Furanoditerpenoid lactones and caesalpin are produced by members of this genus.


A group of phosphate minerals that includes ten mineral species and has the general formula X5(YO4)3Z, where X is usually calcium or lead, Y is phosphorus or arsenic, and Z is chlorine, fluorine, or OH-. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


Feeling of optimism or expectation for a desired outcome.


Non-native species that threaten ecosystems, habitats, or other species and are likely to cause economic or environmental harm or harm to human health.


Behavior-response patterns that characterize the individual.


A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects.


A genus of gram-positive, aerobic bacteria whose species are widely distributed and are abundant in soil. Some strains are pathogenic opportunists for humans and animals.


An intermediate filament protein found in most differentiating cells, in cells grown in tissue culture, and in certain fully differentiated cells. Its insolubility suggests that it serves a structural function in the cytoplasm. MW 52,000.


Systems designed to provide information primarily concerned with the administrative functions associated with the provision and utilization of services; also includes program planning, etc.


Unstable isotopes of gallium that decay or disintegrate emitting radiation. Ga atoms with atomic weights 63-68, 70 and 72-76 are radioactive gallium isotopes.


Organs involved in the production of BLOOD, including the cellular and the molecular components essential in providing defense against foreign organisms or substances.


Alkaloids derived from diterpenes (e.g., KAURANES; CLERODANES) often containing the nitrogen bridge structures. These alkaloids may be divided into C18-, C19-, C20- and bis-diterpene types depending on the number of carbon atoms in their central framework. They are found most often in RANUNCULACEAE (e.g., ACONITUM and DELPHINIUM) and may possess analgesic, antiarrhythmic and anti-inflammatory activities. Some are cardiotoxic by blocking L-TYPE CALCIUM CHANNELS.


Erythrocyte Inclusions
Howell-Jolly Bodies

Pathologic inclusions occurring in erythrocytes.


Compounds with a BENZENE fused to IMIDAZOLES.


Three-carbon SUGAR ACIDS with the formula HOCH2(CHOH)COOH.


A tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. These tumors are thought to have "borderline" aggression, where one-third develop local recurrences, but only rarely metastasize. It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (Segen, Dictionary of Modern Medicine, 1992)


A condition marked by the presence of multiple osteochondromas. (Dorland, 27th ed)


Compounds having the cannabinoid structure. They were originally extracted from Cannabis sativa L. The most pharmacologically active constituents are TETRAHYDROCANNABINOL; CANNABINOL; and CANNABIDIOL.


Infections with viruses of the genus AVULAVIRUS, family PARAMYXOVIRIDAE. This includes NEWCASTLE DISEASE and other infections of domestic fowl.


Set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex. It includes the OLFACTORY NERVE; OLFACTORY BULB; OLFACTORY TRACT; OLFACTORY TUBERCLE; ANTERIOR PERFORATED SUBSTANCE; and OLFACTORY CORTEX.


School-Based Mental Health Services
School Mental Health Services

Services which focus on the mental well-being of pre-college and pre-university students that include COUNSELING and therapy.


Spontaneous Mutation Accumulation
Mutation Accumulation

Concept which describes the incremental effects of MUTATION in living organisms.


Discomfort stemming from muscles, LIGAMENTS, tendons, and bones.


A genus of the family CHLAMYDIACEAE comprising gram-negative non CHLAMYDIA TRACHOMATIS-like species infecting vertebrates. Chlamydophila do not produce detectable quantities of glycogen. The type species is CHLAMYDOPHILA PSITTACI.


Perceptual Disorders
Hemispatial Neglect
Hemisensory Neglect
Sensory Neglect
Somatosensory Discrimination Disorder

Cognitive disorders characterized by an impaired ability to perceive the nature of objects or concepts through use of the sense organs. These include spatial neglect syndromes, where an individual does not attend to visual, auditory, or sensory stimuli presented from one side of the body.


Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.


A false belief regarding the self or persons or objects outside the self that persists despite the facts, and is not considered tenable by one's associates.


Functional inactivation of T- or B-lymphocytes rendering them incapable of eliciting an immune response to antigen. This occurs through different mechanisms in the two kinds of lymphocytes and can contribute to SELF TOLERANCE.


A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor of insulin. Proinsulin, produced by the PANCREATIC BETA CELLS, is comprised sequentially of the N-terminal B-chain, the proteolytically removable connecting C-peptide, and the C-terminal A-chain. It also contains three disulfide bonds, two between A-chain and B-chain. After cleavage at two locations, insulin and C-peptide are the secreted products. Intact proinsulin with low bioactivity also is secreted in small amounts.


Organic compounds containing the nitroso (-N=O) group attached to an organic moiety.


A genus of parasitic FUNGI in the family Nosematidae. Some species are pathogenic for invertebrates of economic importance while others are being researched for possible roles in controlling pest INSECTS. They are also pathogenic in humans.


Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. Amidines include carboxamidines, sulfinamidines and phosphinamidines.


Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation.


Sexual intercourse without consent of the victim.


Advanced Trauma Life Support
Advanced Trauma Life Support Care

A protocol for initial life support care of the severely injured patient.


INFLAMMATION of the TRACHEA that is usually associated with RESPIRATORY TRACT INFECTIONS.


Birth Rate
Age-Specific Fertility Rate
Fertility Rate
Age-Specific Birth Rate

Births in 1 year x 1,000/number of women aged 15-44 at midyear.


Sites where HAZARDOUS SUBSTANCES are deposited. Some have facilities for safely storing, processing, and recycling these waste products.


A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.


A specialized field of physics and engineering involved in studying the behavior and properties of light and the technology of analyzing, generating, transmitting, and manipulating ELECTROMAGNETIC RADIATION in the visible, infrared, and ultraviolet range.


The proportion of patients with a particular disease during a given year per given unit of population.


A species of gram-negative bacteria that is a common inhabitant of the human OROPHARYNX and also cell culture contaminant. It is usually non-pathogenic but it can cause infections in leukemic or immunosuppressed patients.


Saussurea lappa
Saussurea costus
Saussurea

A plant genus of the family ASTERACEAE, order Asterales, subclass Asteridae. It is a source of costus root oil and should not be confused with the genus COSTUS.


Sudden outbreaks of a disease in a country or region not previously recognized in that area, or a rapid increase in the number of new cases of a previous existing endemic disease. Epidemics can also refer to outbreaks of disease in animal or plant populations.


The medical science that deals with the origin, diagnosis, prevention, and treatment of mental disorders.


A species of bacteria that resemble small tightly coiled spirals. Its organisms are known to cause abortion in sheep and fever and enteritis in man and may be associated with enteric diseases of calves, lambs, and other animals.


A genus of ascomycetous yeast in the family Endomycetaceae, order SACCHAROMYCETALES. They have been described as ascus-bearing parasites of basidiocarps, the fruiting bodies of BASIDIOMYCOTA.


Eight-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.


Vulvodynia
Vestibulodynia
Generalized Vulvodynia

Complex pain syndrome with unknown etiology, characterized by constant or intermittent generalized vulva pain (Generalized vulvodynia) or localized burning sensations in the VESTIBULE area when pressure is applied (Vestibulodynia, or Vulvar Vestibulitis Syndrome). Typically, vulvar tissue with vulvodynia appears normal without infection or skin disease. Vulvodynia impacts negatively on a woman's quality of life as it interferes with sexual and daily activities.


Diagnostic Test Approval
In Vitro Diagnostic Device Approval

The process of gaining approval by a government regulatory agency for DIAGNOSTIC REAGENTS AND TEST KITS. This includes any required preclinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance.


Electrophoresis in which cellulose acetate is the diffusion medium.


A suborder of FUNGI in the phylum MICROSPORIDIA, possessing a pansporoblastic membrane.


The study of the anatomical and functional relationships between the nervous system and the endocrine system.


Urination of a large volume of urine with an increase in urinary frequency, commonly seen in diabetes (DIABETES MELLITUS; DIABETES INSIPIDUS).


A genus of nematodes of the superfamily ASCARIDOIDEA whose species usually inhabit the intestine.


The loss of water vapor by plants to the atmosphere. It occurs mainly from the leaves through pores (stomata) whose primary function is gas exchange. The water is replaced by a continuous column of water moving upwards from the roots within the xylem vessels. (Concise Dictionary of Biology, 1990)


A hemoglobin-like oxygen-binding hemeprotein present in the nitrogen-fixing root nodules of leguminous plants. The red pigment has a molecular weight approximately 1/4 that of hemoglobin and has been suggested to act as an oxido-reduction catalyst in symbiotic nitrogen fixation.


Phenomena and pharmaceutics of compounds that selectively bind to a specific receptor and trigger a response. They mimic the action of endogenous biochemical molecules. Their effect can be countered by antagonists (DRUG ANTAGONISM).


A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.


A family of obligately anaerobic Gram-negative bacteria of the order Desulfovibrionales, class DELTAPROTEOBACTERIA. Majority are sulfate-reducing.


Enzymes that catalyze the first step in the beta-oxidation of FATTY ACIDS.


Cephalopelvimetry
Pelvimetry
Cephalopelvic Proportion

Measurement of the dimensions and capacity of the pelvis. It includes cephalopelvimetry (measurement of fetal head size in relation to maternal pelvic capacity), a prognostic guide to the management of LABOR, OBSTETRIC associated with disproportion.


A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.


An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)


Condition with a variable constellation of phenotypes due to deletion polymorphisms at chromosome location 22q11. It encompasses several syndromes with overlapping abnormalities including the DIGEORGE SYNDROME, VELOCARDIOFACIAL SYNDROME, and CONOTRUNCAL AMOMALY FACE SYNDROME. In addition, variable developmental problems and schizoid features are also associated with this syndrome. (From BMC Med Genet. 2009 Feb 25;10:16) Not all deletions at 22q11 result in the 22q11deletion syndrome.


A genus of basidiomycetous smut fungi comprising the loose smuts.


A strain of the species RETICULOENDOTHELIOSIS VIRUS, originally isolated from turkey.


Idazoxan Hydrochloride
RX-781094
Idazoxan

A benzodioxane-linked imidazole that has alpha-2 adrenoceptor antagonist activity.


The various filaments, granules, tubules or other inclusions within mitochondria.


A class of chemicals that contain an anthracene ring with a naphthalene ring attached to it.


A primary systemic vasculitis of small- and some medium-sized vessels. It is characterized by a tropism for kidneys and lungs, positive association with anti-neutrophil cytoplasmic antibodies (ANCA), and a paucity of immunoglobulin deposits in vessel walls.


Professionals who work with persons affected by social disadvantages such as POVERTY; mental and physical illness or disability, and social injustice.  Their focus is on both the individual and his or her environment, including violations of their civil liberties and human rights.


Qualitative and quantitative measurement of MOVEMENT patterns.


Various material objects and items in the home. It includes temporary or permanent machinery and appliances. It does not include furniture or interior furnishings (FURNITURE see INTERIOR DESIGN AND FURNISHINGS; INTERIOR FURNISHINGS see INTERIOR DESIGN AND FURNISHINGS).


Agents capable of exerting a harmful effect on the body.


Cultural and linguistic competence is a set of congruent behaviors, attitudes, and policies that come together in a system, agency, or among professionals that enables effective work in cross-cultural situations. Competence implies the capacity to function effectively as an individual and an organization within the context of the cultural beliefs, behaviors, and needs presented by consumers and their communities.


A genus of intestinal parasitic nematodes occurring in animals and man.


The ability to attribute mental states (e.g., beliefs, desires, feelings, intentions, thoughts, etc.) to self and to others, allowing an individual to understand and infer behavior on the basis of the mental states. Difference or deficit in theory of mind is associated with ASPERGER SYNDROME; AUTISTIC DISORDER; and SCHIZOPHRENIA, etc.


An irregular unpaired bone situated at the SKULL BASE and wedged between the frontal, temporal, and occipital bones (FRONTAL BONE; TEMPORAL BONE; OCCIPITAL BONE). Sphenoid bone consists of a median body and three pairs of processes resembling a bat with spread wings. The body is hollowed out in its inferior to form two large cavities (SPHENOID SINUS).


The withholding of food in a structured experimental situation.


Necrosis of bone following radiation injury.


Proteins involved in the transport of nucleobases such as PYRIMIDINES and PURINES across membranes.


A plant family of the order ROSALES, subclass Rosidae, class Magnoliopsida. They are deciduous woody shrubs with alternate leaves. The flowers are in terminal racemes with 5 petals and 5 stamens.


An antineoplastic agent that acts by alkylation.


A genus of short, aerobic, gram-negative rods which are obligate methylotrophs, growing on one-carbon compounds other than methane. (From Bergey's Manual of Determinative Bacteriology, 9th ed)


A 34-amino acid polypeptide antibiotic produced by Streptococcus lactis. It has been used as a food preservative in canned fruits and vegetables, and cheese.


Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.


A family of RNA plant viruses infecting disparate plant families. They are transmitted by specific aphid vectors. There are three genera: LUTEOVIRUS; Polerovirus; and Enamovirus.


An actinomycete from which the antibiotic OLEANDOMYCIN is obtained.


An accumulation of PUS in the uterine cavity (UTERUS). Pyometra generally indicates the presence of infections.


A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.


Databases, Chemical
Databases, Molecular

Databases devoted to knowledge about specific molecules.


An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)


An alternative to amputation in patients with neoplasms, ischemia, fractures, and other limb-threatening conditions. Generally, sophisticated surgical procedures such as vascular surgery and reconstruction are used to salvage diseased limbs.


Derivatives of gluconic acid (the structural formula HOCH2(CHOH)4COOH), including its salts and esters.


A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb.


Posterior displacement of the TONGUE toward the PHARYNX. It is often a feature in syndromes such as in PIERRE ROBIN SYNDROME and DOWN SYNDROME and associated with AIRWAY OBSTRUCTION during sleep (OBSTRUCTIVE SLEEP APNEAS).


A subfamily of HERPESVIRIDAE characterized by a relatively long replication cycle. Genera include: CYTOMEGALOVIRUS; MUROMEGALOVIRUS; and ROSEOLOVIRUS.


Study subjects in COHORT STUDIES whose outcomes are unknown e.g., because they could not or did not wish to attend follow-up visits.(from Dictionary of Epidemiology, 5th ed.)


A genetically engineered, fully humanized immunoglobulin G4 monoclonal antibody that binds to the PD-1 RECEPTOR, activating an immune response to tumor cells. It is used as monotherapy or in combination with IPILIMUMAB for the treatment of advanced malignant MELANOMA. It is also used in the treatment of advanced or recurring NON-SMALL CELL LUNG CANCER; RENAL CELL CARCINOMA; and HODGKIN'S LYMPHOMA.


The sodium salt of BENZOIC ACID. It is used as an antifungal preservative in pharmaceutical preparations and foods. It may also be used as a test for liver function.


The sole species in the genus Paracentrotus.


A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.


A plant genus in the family CONVOLVULACEAE best known for morning glories (a common name also used with CONVOLVULUS) and sweet potato.


A plant genus of the family PRIMULACEAE that contains triterpenoid saponins.


Azoles of one NITROGEN and two double bonds that have aromatic chemical properties.


Nasal Epithelium
Schneiderian Membrane
Nasal Mucosa

The ciliated mucoperostium lining of the MAXILLARY SINUS.


Triangular Fibrocartilage
Triangular Fibrocartilage Complex

Ligamentous and cartilaginous structures that suspend the distal RADIUS and ulnar CARPAL BONES from the distal ULNA. It is the main stabilizer of distal radioulnar joint (WRIST JOINT).


Dextranase
Glucanase 447-G
Endo-Dextranase

Enzyme that hydrolyzes DEXTRAN to OLIGOSACCHARIDES.


The vestibular part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The vestibular nerve fibers arise from neurons of Scarpa's ganglion and project peripherally to vestibular hair cells and centrally to the VESTIBULAR NUCLEI of the BRAIN STEM. These fibers mediate the sense of balance and head position.


The anamorphic form of the yeast DEKKERA. It is implicated as a spoilage microorganism in wines.


Drug Contamination, Physical
Drug Contamination, Chemical
Drug Adulteration
Drug Contamination, Microbial
Drug Impurity
Drug Contamination

The presence of chemical substance other than the desired pharmaceutical compound manufactured.


Toxins isolated from the venom of Laticauda semifasciata, a sea snake (Hydrophid); immunogenic, basic polypeptides of 62 amino acids, folded by four disulfide bonds, block neuromuscular end-plates irreversibly, thus causing paralysis and severe muscle damage; they are similar to Elapid neurotoxins.


Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.


A subdiscipline of genetics which deals with the cytological and molecular analysis of the CHROMOSOMES, and location of the GENES on chromosomes, and the movements of chromosomes during the CELL CYCLE.


Penal institutions, or places of confinement for prisoners.


Saturated derivatives of the steroid pregnane. The 5-beta series includes PROGESTERONE and related hormones; the 5-alpha series includes forms generally excreted in the urine.


Light brown pigmented macules associated with NEUROFIBROMATOSIS and Albright's syndrome (see FIBROUS DYSPLASIA, POLYOSTOTIC).


Strong alkaline chemicals that destroy soft body tissues resulting in a deep, penetrating type of burn, in contrast to corrosives, that result in a more superficial type of damage via chemical means or inflammation. Caustics are usually hydroxides of light metals. SODIUM HYDROXIDE and potassium hydroxide are the most widely used caustic agents in industry. Medically, they have been used externally to remove diseased or dead tissues and destroy warts and small tumors. The accidental ingestion of products (household and industrial) containing caustic ingredients results in thousands of injuries per year.


Use of word stimulus to strengthen a response during learning.


A daidzein derivative occurring naturally in forage crops which has some estrogenic activity.


Embryonic and fetal development that takes place in an artificial environment in vitro.


Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS.


Endosymbiosis Mutualism Commensalism Symbiosis

A form of symbiosis between two organisms of different species in which one of them benefits from the association whereas the other is largely unaffected or not significantly harmed or benefiting from the relationship.


Conversion into nitroso compounds. An example is the reaction of nitrites with amino compounds to form carcinogenic N-nitrosamines.


A cytostatic triazole derivative which is not to be confused with guanazolo, the generic name for 8-azaguanine.


The discipline concerned with WEIGHT REDUCTION in patients with OBESITY.


The development by insects of resistance to insecticides.


A superfamily of nematodes of the order RHABDITIDA. Characteristics include an open tube stoma and an excretory system with lateral canals.


Animal population groups or individual animals that reside in captivity at a zoological park.


Inflammation of the tonsils, especially the PALATINE TONSILS but the ADENOIDS (pharyngeal tonsils) and lingual tonsils may also be involved. Tonsillitis usually is caused by bacterial infection. Tonsillitis may be acute, chronic, or recurrent.


A genus of green plants in the family CHARACEAE, phylum STREPTOPHYTA. They are found in shallow to deep waters of soft water or acid lakes and bogs.


The measure of the level of heat of a human or animal.


A plant genus of the family ASTERACEAE. Members contain CAROTENOIDS, essential oils (OILS, VOLATILE), flavonoids, mucilage, SAPONINS, and STEROLS. The plants are used both topically and internally. The common name of Marigold is also used for TAGETES.


Products that are cosmetics and products that are both a cosmetic and a drug, such as dandruff shampoo, fluoride containing toothpastes, antiperspirant deodorants, and moisturizers and makeup containing sunscreen.


A genus of gram-negative aerobic bacteria that occurs free-living in the soil or associated with the roots of cereal crops or grasses (POACEAE).


Form of social behavior in which assistance is sought from others.


Salts of hydrobromic acid, HBr, with the bromine atom in the 1- oxidation state. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.


A psychological test consisting of true/false items. It is used as a diagnostic screening or clinical assessment of adults who evidence problematic emotional and interpersonal symptoms or who are undergoing PSYCHOTHERAPY or a psychodiagnostic evaluation.


Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.


A species of parasitic nematode causing Malayan filariasis and having a distribution centering roughly on the Malay peninsula. The life cycle of B. malayi is similar to that of WUCHERERIA BANCROFTI, except that in most areas the principal mosquito vectors belong to the genus Mansonia.


A mitosporic fungal genus used in the fermentation of wine. Teleomorphs are in the genus HANSENIASPORA.


Any technique by which an unknown color is evaluated in terms of standard colors. The technique may be visual, photoelectric, or indirect by means of spectrophotometry. It is used in chemistry and physics. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


Training of Trainers
Teacher Education
Teacher Training

A curriculum-centered process of equipping individuals with professional knowledge and skills required to become effective teachers.


A genus of plant viruses in the family GEMINIVIRIDAE that are transmitted in nature by whitefly Bemisia tabaci.


A class of enzymes that catalyze the cleavage of C-C, C-O, and C-N, and other bonds by other means than by hydrolysis or oxidation. (Enzyme Nomenclature, 1992) EC 4.


The mechanical laws of fluid dynamics as they apply to urine transport.


A member of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, originally isolated from human nasopharyngeal aspirates in patients with respiratory disease.


Inflammation of the vagina characterized by pain and a purulent discharge.


Sublingual Absorption
Buccal Absorption
Oral Mucosal Absorption

Uptake of substances into the body via the inner mucosal surface of the cheeks.


Aminoglycoside produced by Streptomyces hygroscopicus. It is used as an anthelmintic against swine infections by large roundworms, nodular worms, and whipworms.


Peri-implant Endosseous Healing
Osseointegration

The growth action of bone tissue as it assimilates surgically implanted devices or prostheses to be used as either replacement parts (e.g., hip) or as anchors (e.g., endosseous dental implants).


A genus of gram-negative, aerobic, motile bacteria that occur in water and soil. Some are common inhabitants of the intestinal tract of vertebrates. These bacteria occasionally cause opportunistic infections in humans.


The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.


Surgical removal of the thymus gland. (Dorland, 28th ed)


Gap between individuals, households, businesses and geographic areas at different socioeconomic levels with regard to both their opportunities to access electronic  information and communication technologies (ICTs). Their use of the Internet for a wide variety of activities, reflects various differences among and within countries.


A double gliding joint formed by the CLAVICLE, superior and lateral parts of the manubrium sterni at the clavicular notch, and the cartilage of the first rib.


Death and putrefaction of tissue usually due to a loss of blood supply.


Incidental Discovery
Incidental Findings

Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.


An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.


Viral Plaque Assay
Bacteriophage Plaque Assay

Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.


Works on research using processes by which the reliability and relevance of a procedure for a specific purpose are established.


Airplanes
Ejection Seats
Aircraft
Helicopters

A weight-carrying structure for navigation of the air that is supported either by its own buoyancy or by the dynamic action of the air against its surfaces. (Webster, 1973)


Leaky Mutation
Loss of Function Mutation
Null Mutation

A mutation that causes a decrease in or elimination of a gene product's activity.


Crafts, trades, professions, or other means of earning a living.


A man-made radioactive actinide with atomic symbol Fm, and atomic number 100. Its known isotopes range from 244-254 and 256-258. Its valence can be +2 or +3. Like einsteinium, it was discovered in 1952 in the debris from a thermonuclear explosion.


A genus of strictly anaerobic ultrathermophilic archaea, in the family THERMOCOCCACEAE, occurring in heated seawaters. They exhibit heterotrophic growth at an optimum temperature of 100 degrees C.


Thyroid, Ectopic
Thyroid Dysgenesis
Thyroid Hypoplasia
Thyroid Agenesis

Defective development of the THYROID GLAND. This concept includes thyroid agenesis (aplasia), hypoplasia, or an ectopic gland. Clinical signs usually are those of CONGENITAL HYPOTHYROIDISM.


Transmission of information over distances via electronic means.


Strategy for the analysis of RANDOMIZED CONTROLLED TRIALS AS TOPIC that compares patients in the groups to which they were originally randomly assigned.


Involuntary contraction or twitching of the muscles. It is a physiologic method of heat production in man and other mammals.


Conditions in which a bifurcation or trifurcation of the molar tooth root becomes denuded as a result of periodontal disease. It may be followed by tooth mobility, temperature sensitivity, pain, and alveolar bone resorption.


A condition in which HEART VENTRICLES exhibit impaired function.


Compounds that bind to and inhibit the activation of ANDROGEN RECEPTORS.


A highly neurotoxic polypeptide from the venom of the honey bee (Apis mellifera). It consists of 18 amino acids with two disulfide bridges and causes hyperexcitability resulting in convulsions and respiratory paralysis.


A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)


A subjective psychometric response scale used to measure distinct behavioral or physiological phenomena based on linear numerical gradient or yes/no alternatives.