Chronic Progressive Subcortical Encephalopathy

Encephalopathy, Subcortical, Chronic Progressive

Subcortical Encephalopathy, Chronic Progressive

Encephalopathy, Chronic Progressive Subcortical

A form of dementia characterized by brain lesions in the deep white-matter, also known as subcortical dementia.


Simian AIDS Vaccines
SIV Vaccines
SIV Vaccine
SAIDS Vaccines

Vaccines or candidate vaccines designed to prevent SAIDS; (SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME); and containing inactivated SIMIAN IMMUNODEFICIENCY VIRUS or type D retroviruses or some of their component antigens.


Mini Nutrition Assessment
Nutrition Index
Nutrition Indexes
Nutrition Indices
Nutritional Index
Assessment, Nutrition
Nutritional Assessment
Nutrition Assessment
Prognostic Nutritional Index (PNI)
Prognostic Nutritional Index
Nutrition Assessments
Mini Nutritional Assessment

Indexes used in evaluating NUTRITIONAL STATUS.


Drug Packaging
Packaging, Drug
Drug Containers and Closures
Drug Containers

Containers, packaging, and packaging materials for drugs and BIOLOGICAL PRODUCTS. These include those in ampule, capsule, tablet, solution or other forms. Packaging includes immediate-containers, secondary-containers, and cartons. In the United States, such packaging is controlled under the Federal Food, Drug, and Cosmetic Act which also stipulates requirements for tamper-resistance and child-resistance. Similar laws govern use elsewhere. (From Code of Federal Regulations, 21 CFR 1 Section 210, 1993) DRUG LABELING is also available.


Placental Development
Hemochorial Placentation
Hemochorial Placental Development
Placentation

The development of the PLACENTA, a highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products between mother and FETUS. The process begins at FERTILIZATION, through the development of CYTOTROPHOBLASTS and SYNCYTIOTROPHOBLASTS, the formation of CHORIONIC VILLI, to the progressive increase in BLOOD VESSELS to support the growing fetus.


Microbial Community
Microbial Community Composition
Microbial Community Structure
Microbiome, Human
Human Microbiome
Microbiota
Microbiome

The full collection of microbes (bacteria, fungi, virus, etc.) that naturally exist within a particular biological niche as identified by the presence of their genomic sequence regardless of whether or not they can be cultured.


Prostatic Hypertrophy
Prostatic Adenoma
Prostatic Hyperplasia, Benign
Benign Prostatic Hyperplasia
Adenoma, Prostatic
Prostatic Hypertrophy, Benign
Prostatic Hyperplasia

A disease caused by hyperplastic process of non-transformed prostatic cells.


Gemtuzumab
CMA 676
Gemtuzumab Ozogamicin
Gemtuzumab-Ozogamicin
CMA-676
Mylotarg

Immunotoxin that consists of an anti-CD33 (CD33 ANTIGEN) monoclonal antibody conjugated to CALICHEAMICIN. It is used for the treatment of ACUTE MYELOID LEUKEMIA.


Slow Reaction Substance of Anaphylaxis Receptors

Slow Reacting Substance of Anaphylaxis Receptors

Cell-surface receptors that bind LEUKOTRIENES with high affinity and trigger intracellular changes influencing the behavior of cells. The leukotriene receptor subtypes have been tentatively named according to their affinities for the endogenous leukotrienes LTB4; LTC4; LTD4; and LTE4.


An androstanol non-depolarizing neuromuscular blocking agent. It has a mono-quaternary structure and is a weaker nicotinic antagonist than PANCURONIUM.


NI-250 Protein
Neurite Growth Inhibitor 35-350
NI-220 Protein
Nogo-C Protein
Nogo-A Protein
Nogo Proteins
Nogo-B Protein
NI-35 Protein
Nogo-66 Protein
NI-35-250
Nogo Protein
Reticulon 4-B Protein
Reticulon-4 Protein

Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system.


Watery Diarrhea, Hypokalemia, and Achlorhydria Syndrome

Vasoactive Intestinal Peptide-Producing Tumor

Vasoactive Intestinal Peptide (VIP) Tumor

Watery Diarrhea with Hypokalemic Alkalosis

A tumor that secretes VASOACTIVE INTESTINAL PEPTIDE, a neuropeptide that causes VASODILATION; relaxation of smooth muscles; watery DIARRHEA; HYPOKALEMIA; and HYPOCHLORHYDRIA. Vipomas, derived from the pancreatic ISLET CELLS, generally are malignant and can secrete other hormones. In most cases, Vipomas are located in the PANCREAS but can be found in extrapancreatic sites.


Angiotensin AT1 Receptor
Angiotensin Type 1b Receptor
Angiotensin II Type 1a Receptor
Angiotensin II Type 1 Receptor
Angiotensin Type 1 Receptor
Receptor, Angiotensin, Type 1a
Angiotensin Type 1a Receptor
Angiotensin AT1a Receptor
Receptor, Angiotensin, Type 1
Receptor, Angiotensin II Type 1b
Receptor, Angiotensin II Type 1
Receptor, Angiotensin, Type 1b
Angiotensin II Type 1b Receptor
Angiotensin AT1b Receptor
Receptor, Angiotensin II Type 1a

A subtype of angiotensin receptor found primarily in rodent species that have two type 1 angiotensin receptor genes.


Generalized Tonic-Clonic Seizures
Nonepileptic Seizures
Seizures, Vestibular
Complex Partial Seizures
Absence Seizures
Atonic Seizures
Tonic-Clonic Seizures
Convulsion, Non-Epileptic
Seizures, Vertiginous
Seizures, Somatosensory
Seizures, Olfactory
Seizures, Epileptic
Seizures, Gustatory
Seizures, Clonic
Seizures, Visual
Tonic Seizures
Non-Epileptic Seizures
Petit Mal Convulsion
Jacksonian Seizure
Clonic Seizures
Myoclonic Seizures
Partial Seizures
Seizures, Convulsive
Seizures, Sensory
Convulsive Seizures
Epileptic Seizures
Convulsions
Seizures
Seizures, Motor
Seizures, Tonic-Clonic
Seizures, Auditory
Seizures, Generalized
Generalized Absence Seizures
Seizures, Tonic
Generalised Tonic-Clonic Seizures
Single Seizure
Atonic Absence Seizures
Seizures, Focal

Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or "seizure disorder."


Organizational Productivity
Productivity, Organizational
Program Efficiency
Efficiency, Administrative
Administrative Efficiency
Efficiency, Organizational

The capacity of an organization, institution, or business to produce desired results with a minimum expenditure of energy, time, money, personnel, material, etc.


Atrophy, Muscle
Neurogenic Muscular Atrophy
Neurotrophic Muscular Atrophy
Muscular Atrophy

Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.


A diarylpyrimidine derivative and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 that is used in the treatment of HIV INFECTIONS. It is also used in combination with other ANTI-HIV AGENTS, since ANTIVIRAL DRUG RESISTANCE emerges rapidly when it is used alone.


Ambiguous Genitalia
Intersex Conditions
Disorders of Sexual Development
Sex Development Disorders
Genital Ambiguity
Disorders of Sex Development
Intersexuality
Sex Differentiation Disorders
Sexual Differentiation Disorders
Sexual Development Disorders
Pseudohermaphroditism
Hermaphroditism

An historical term for a variety of abnormalities in sex development that lead to anomalies in the reproductive tract and/or external genitalia.


Transmembrane proteins involved in axonal guidance of peripheral neurons in the developing CNS of invertebrates. Semaphorin-1 refers to the class of SEMAPHORINS with an extracellular sema domain and a short cytoplasmic domain. Sema-1 was first identified in grasshopper as fasciclin IV, and has since been described in Drosophila and C. elegans. Two distinct members of this class of semaphorins exist: SEMA-1a (the original sema-1) and SEMA-1b, a homologous protein isolated from Drosophila which may be more important for neuronal differentiation than migration.


Cichlidae
Cichlids
Oreochromis nilotica
Tilapia nilotica
Nile Tilapia
Oreochromis niloticus
Cichlid Fish

Species of genus Oreochromis formerly in genus Tilapia.


Outpatient Infusion Therapies
Infusion Therapy, Outpatient
Outpatient Infusion Therapy
Home Infusion Therapy
Therapy, Outpatient Infusion
Home Infusion Therapies
Therapies, Outpatient Infusion
Infusion Therapies, Outpatient
Infusion Therapy, Home
Therapy, Home Infusion
Infusion Therapies, Home
Therapies, Home Infusion

Use of any infusion therapy on an ambulatory, outpatient, or other non-institutionalized basis.


Traditional Birth Attendant
Midwife
Midwives
Midwifery

The practice of assisting women in childbirth.


Rescue Stretchers
Emergency Room Stretchers
Gurneys
Stretchers
Patient Litters
Patient Holding Stretchers
Wheeled Stretchers
Patient Trolleys
Ambulance Stretchers

Bed-like structures for transporting or temporarily holding patients.


Alkanal Monooxygenase (FMN-Linked)
Alkanal Monooxygenase beta Chain
Luciferases, Vibrio
Alkanal Monooxygenase alpha Chain
Luciferases, Photorhabdus
Bacterial Luciferase alpha Chain
Bacterial Luciferase beta Chain
Luciferases, Bacterial
Luciferases, Photobacterium

Luciferases from BACTERIA such as PHOTOBACTERIUM; VIBRIO; and PHOTORHABDUS.


Tien ma
Gastrodia Elata Extract
Gastrodia elata
Gastrodia

A plant genus of the family ORCHIDACEAE which depends on the fungus Armillaria mellea to complete its life cycle. It is an ingredient of Zhenxuanyin (DRUGS, CHINESE HERBAL).


Calvin Cycle
Dark Reactions of Photosynthesis
Calvin-Benson Cycle
Carbon Fixation, Photosynthetic
Photosynthesis
Calvin-Benson-Bassham Cycle
Reductive Pentose Phosphate Cycle

The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide using energy obtained from light rather than from the oxidation of chemical compounds. Photosynthesis comprises two separate processes: the light reactions and the dark reactions. In higher plants; GREEN ALGAE; and CYANOBACTERIA; NADPH and ATP formed by the light reactions drive the dark reactions which result in the fixation of carbon dioxide. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)


Trained lay women who provide emotional and/or physical support during obstetric labor and the postpartum period for mothers and their partners.


North Asian Tick Typhus
Rickettsia akari Infection
African Tick-Bite Fever
Rickettsia slovaca Infection
Spotted Fevers
Rickettsia africae Infection
Spotted Fever Group Rickettsioses
Japanese Spotted Fever
Rickettsia aeschlimannii Infection
TIBOLA
Rickettsialpox
Tick-Borne Lymphadenopathy
Rickettsia australis Infection
Flinders Island Spotted Fever
Spotted Fever Group Rickettsiosis
Far Eastern Spotted Fever
Queensland Tick Typhus

A group of arthropod-borne diseases caused by spotted fever bio-group members of RICKETTSIA. They are characterized by fever, headache, and petechial (spotted) rash.


Urinary Tract Physiological Phenomenon
Urinary Tract Physiological Process
Urinary Physiology Phenomena
Urinary Tract Physiology
Urinary Tract Physiological Processes
Urinary Physiological Concepts
Urinary Physiology Phenomenon
Urinary Tract Physiological Phenomena
Urinary Physiology Concepts
Urinary Physiology
Physiology, Urinary Tract

Properties, functions, and processes of the URINARY TRACT as a whole or of any of its parts.


Bis(5'-Nucleosidyl)Tetraphosphate
Dinucleoside Monophosphates
Bis(5'-Nucleosidyl)Phosphates
Dinucleoside Polyphosphates
Dinucleoside Diphosphates
Dinucleoside Phosphates
Dinucleoside Triphosphates
Dinucleoside Oligophosphates
Bis(5'-Nucleosidyl)Oligophosphates
Deoxydinucleoside Phosphates
Dinucleoside Tetraphosphates

A group of compounds which consist of a nucleotide molecule to which an additional nucleoside is attached through the phosphate molecule(s). The nucleotide can contain any number of phosphates.


Monkeys Anthropoidea Anthropoids Haplorhini

A non-taxonomic, non-specific term for the smaller longer-tailed PRIMATES.


Adenosine Triphosphatases
DNA-Dependent ATPase
ATPases
ATPase
Adenosine Triphosphatase
Adenosinetriphosphatase
DNA-Dependent Adenosinetriphosphatases
ATPase, DNA-Dependent

A group of enzymes which catalyze the hydrolysis of ATP. The hydrolysis reaction is usually coupled with another function such as transporting Ca(2+) across a membrane. These enzymes may be dependent on Ca(2+), Mg(2+), anions, H+, or DNA.


Ready-Prepared Foods
Ready-To-Eat Meals
Meals, Ready-To-Eat
Convenience Foods
Fast Foods

Prepared food that is ready to eat or partially prepared food that has a final preparation time of a few minutes or less.


Serum Response Factor Accessory Protein 1

A member of the ternary complex family of ets-related transcription factors that is regulated by MITOGEN-ACTIVATED PROTEIN KINASES such as EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; and P38 MITOGEN-ACTIVATED PROTEIN KINASES.


Pentobarbitone
Sagatal
Etaminal
Mebubarbital
Ethaminal
Diabutal
Pentobarbital Sodium
Mebumal
Nembutal
Pentobarbital, Monosodium Salt
Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)


Right Aortic Arch with Left Ligamentum Arteriosum

Congenital vascular malformation in which the AORTA arch and its branches encircle the TRACHEA and ESOPHAGUS. Signs and symptoms include DYSPNEA; RESPIRATORY SOUNDS, especially with eating, DYSPHAGIA, persistent cough, and GASTROESOPHAGEAL REFLUX or may be asymptomatic. Two most common types are double aortic arch and right aortic arch. It may be associated with other anomalies (e.g., DIGEORGE SYNDROME).


A piperazine derivative, PHOSPHODIESTERASE 5 INHIBITOR and VASODILATOR AGENT that is used as a UROLOGICAL AGENT in the treatment of ERECTILE DYSFUNCTION.


Urocortin 1
Urocortin 3
Ucn II
Ucn III
Urocortins
Urocortin
Urocortin II
Urocortin 2
Urocortin III
Urocortin I

Neuropeptides of about 40 amino acids which are structurally similar to CORTICOTROPIN-RELEASING FACTOR. Unlike CRF acting primarily through type 1 CRF RECEPTORS, urocortins signal preferentially through type 2 CRF receptors. Urocortins have wide tissue distribution from fish to mammals, and diverse functions. In mammals, urocortins can suppress food intake, delays gastric emptying, and decreases heat-induced edema.


An antibiotic mixture originally isolated from Streptomyces pristinaspiralis. It is a mixture of compounds from STREPTOGRAMIN GROUP A: pristinamycin IIA and IIB and from STREPTOGRAMIN GROUP B: pristinamycin IA, pristinamycin IB, pristinamycin IC.


The determination of oxygen-hemoglobin saturation of blood either by withdrawing a sample and passing it through a classical photoelectric oximeter or by electrodes attached to some translucent part of the body like finger, earlobe, or skin fold. It includes non-invasive oxygen monitoring by pulse oximetry.


SOX-18 Transcription Factor
SOX7 Transcription Factor
Group F SOX Transcription Factors
SOXF Transcription Factors
SOX18 Transcription Factor
SOX-7 Transcription Factor
SOX17 Transcription Factor
SOX-17 Transcription Factor

A subclass of closely-related SOX transcription factors. Members of this subclass are expressed in VASCULAR ENDOTHELIAL CELLS and may play a role in vasculogenesis.


Metabolic Diseases, Acquired, Nervous System

Central Nervous System Metabolic Disorders

Nervous System Acquired Metabolic Diseases

Metabolic Disorders, Central Nervous System

Acquired Metabolic Diseases, Nervous System

Metabolic Disorder, Central Nervous System, Acquired

Brain dysfunction or damage caused by acquired (i.e., non-inborn) metabolic disorders. Associated conditions include ENDOCRINE DISEASES; WATER-ELECTROLYTE IMBALANCE; KIDNEY DISEASES; LIVER DISEASES; anoxia (HYPOXIA, BRAIN); nutritional disorders (see NUTRITIONAL AND METABOLIC DISEASES); an encephalopathy associated with HEMODIALYSIS; and other disorders. (From Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, pp208-260)


Cicuta
Cicuta major
Cicuta maculata
Hemlock, Spotted Water
Hemlock, Water
Water Hemlock
Cicuta virosa

Cicuta maculata is toxic. Its foliage contains a complex unsaturated alcohol that causes convulsions.


Psychology, Existential
Existential Psychology
Existentialism

Philosophy based on the analysis of the individual's existence in the world which holds that human existence cannot be completely described in scientific terms. Existentialism also stresses the freedom and responsibility of the individual as well as the uniqueness of religious and ethical experiences and the analysis of subjective phenomena such as anxiety, guilt, and suffering. (APA, Thesaurus of Psychological Index Terms, 8th ed.)


Antigen 4F2
4F2 Antigen
FRP-1 protein
CD98 Transport Proteins
Human 4F2 Cell-Surface Antigen
Human 4F2 Antigen
CD98 Antigens
Human Lymphocyte Activation Antigen 4F2
4F2-antigen
H4F2 Antigen
CD98 Antigen
Fusion Regulatory Protein-1
Antigens, CD98

A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (FUSION REGULATORY PROTEIN 1, HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (FUSION REGULATORY PROTEIN 1, LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.


Ginger, Wild
Snakeroot, Canada
Asarum
Wild Ginger
Asarum canadense
Canada Snakeroot

A plant genus of the family ARISTOLOCHIACEAE which was used medicinally by North American Indians. The common name of 'snakeroot' is also used for many other plants, including SANICULA; or ARISTOLOCHIA; or Polygala.


Wuweizi
Schisandra chinensis
Schisandra
Schizandra
Bay Starvine
Wu wei zi
Schisandra glabra
Gomisi

A species of Schisandra which shares the common name wild sarsaparilla with some species of SILAX and ARALIA.


DRK1 Potassium Channel
Shab Potassium Channels
Kv2 Potassium Channels
KCNB2 Potassium Channel
Kv2.1 Potassium Channel
CDRK Potassium Channel
Kv2.2 Potassium Channel

A subfamily of shaker potassium channels that shares homology with its founding member, Shab protein, Drosophila. They regulate delayed rectifier currents in the NERVOUS SYSTEM of DROSOPHILA and in the SKELETAL MUSCLE and HEART of VERTEBRATES.


Plasma Membrane Fatty Acid-Binding Protein

Fatty Acid-Binding Protein, Cardiac Myocyte

Fatty Acid-Binding Proteins, Myocardial-Specific

Fatty Acid-Binding Proteins, Plasma-Membrane Specific

Adipocyte-Specific Fatty Acid-Binding Protein

Fatty Acid-Binding Proteins, Intestinal-Specific

Fatty Acid-Binding Proteins, Liver-Specific

Fatty Acid-Binding Proteins, Brain-Specific

Fatty Acid-Binding Proteins, Adipocyte-Specific

Fatty Acid-Binding Proteins, Cytosolic-Specific

Intracellular proteins that reversibly bind hydrophobic ligands including: saturated and unsaturated FATTY ACIDS; EICOSANOIDS; and RETINOIDS. They are considered a highly conserved and ubiquitously expressed family of proteins that may play a role in the metabolism of LIPIDS.


Mixed Central and Obstructive Sleep Apnea

Sleep Apnea, Mixed Central and Obstructive

Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.


Mustela lutreola
Sea Mink
Mustela vison
European Mink
Mustela macrodon
American Mink
Mink

Carnivores of genus Mustela of the family MUSTELIDAE. The European mink, which has white upper and lower lips, was widely trapped for commercial purposes and is classified as endangered. The American mink, lacking a white upper lip, is farmed commercially.


Cyberspace
Internet
World Wide Web
Cyber Space

A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.


A term used in Russian literature for BHT that has no relationship to IONONES.


Interosseous Ligament
Interosseal Ligament
Ligaments

Shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. They are pliant, tough, and inextensile.


Transcellular Pathways
Transcytotic Pathways
Transcellular Transport
Transcytosis

The mechanisms by which materials are transported through cells.


Solute Carrier Family 23 (Nucleobase Transporters), Member 2

Solute Carrier Family 23 (Nucleobase Transporters), Member 1

Sodium-Dependent Vitamin C Transporter 1

Sodium-Dependent Vitamin C Transporter 2

Membrane transport proteins that actively co-transport ASCORBIC ACID and sodium ions across the CELL MEMBRANE. Dietary absorption of VITAMIN C is highly dependent upon this class of transporters and a subset of SODIUM GLUCOSE TRANSPORTERS which transport the oxidized form of vitamin C, DEHYDROASCORBIC ACID.


Pithecia
Callicebinae
Chiropotes
Pithecinae
Cacajao
Pitheciidae
Pitheciinae
Bearded Sakis
Plecturocebus
Cheracebus

A family of New World monkeys in the infraorder PLATYRRHINI consisting of two subfamilies: Callicebinae and Pitheciinae.


A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.


Acute Myeloid Leukemia 1 Protein
Core-Binding Factor Alpha 2 Protein
Runx1 Protein
Acute Myeloid Leukemia 1B Protein
Core Binding Factor Alpha 2 Subunit
Acute Myeloid Leukemia 1A Protein
AML1C Protein
Acute Myeloid Leukemia 1D Protein
AML1A Protein
Acute Myeloid Leukemia 1C Protein
AML1B Protein
Pebp2a2 Protein
Runt-Related Transcription Factor 1
AML1D Protein

A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.


A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)


Chondrus
Carrageen
Moss, Irish
Chondrus crispus

Species of Chondrus that is one of the primary commercial sources of CARRAGEENAN.


Ferrimagnets Ferrimagnet Electromagnets Magnets Ferromagnet Ferromagnets


Thiazide Sensitive NaCl Cotransporter Inhibitors

Sodium Chloride Cotransporter Inhibitors

Diuretics characterized as analogs of 1,2,4-benzothiadiazine-1,1-dioxide. All have a common mechanism of action and differ primarily in the dose required to produce a given effect. They act directly on the kidney to increase the excretion of sodium chloride and water and also increase excretion of potassium ions.


Aiglonyl Sulpitil vertigo-neogama Sulperide Synédil Sulp Tepavil neogama Arminol Desisulpid Psicocen Sulpor Ekilid Dolmatil Dogmatil Pontiride Sulpiride Guastil Deponerton Eglonyl Meresa Lebopride Vertigo-Meresa Digton Sulpivert

A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)


Magnetic Resonance Angiography
Angiography, Magnetic Resonance
Perfusion Magnetic Resonance Imaging
Perfusion Weighted MRI
MRI Angiography

A diagnostic technique for measuring the rate at which blood is delivered to tissue. In perfusion MRI, an exogenous contrast agent is usually injected to provide superior tissue contrast and easy delineation of perfusion abnormalities. Endogenous markers can also be used.


Dendrophtora
Mistletoe, Argentine
Tapinanthus
Ligaria cuneifolia
Mistletoe, African
Loranthaceae
Taxillus

The showy mistletoe plant family of the order Santalales, subclass Rosidae, class Magnoliopsida. This includes parasitic tropical plants with haustoria connecting to the hosts. The leaves are opposite and thick. The flowers (4-7) have both calyx and corolla. The fruit is a berry with one seed.


Sagittal Sinus Septic Phlebitis
Phlebitis, Sagittal Sinus, Septic
Septic Phlebitis, Sagittal Sinus
Sagittal Sinus Thrombosis
Thrombosis, Sagittal Sinus
Sagittal Sinus Thrombophlebitis

Formation or presence of a blood clot (THROMBUS) in the SUPERIOR SAGITTAL SINUS or the inferior sagittal sinus. Sagittal sinus thrombosis can result from infections, hematological disorders, CRANIOCEREBRAL TRAUMA; and NEUROSURGICAL PROCEDURES. Clinical features are primarily related to the increased intracranial pressure causing HEADACHE; NAUSEA; and VOMITING. Severe cases can evolve to SEIZURES or COMA.


Cephalothin
Cefalotina Normon
Cefalotina Sodica Spaly
Ceftina
Seffin
Sodium Cephalothin
Cefalotin
Keflin
Cephalothin Monosodium Salt


Oropouche Virus Infection
Oropouche Fever
Infections, Bunyaviridae
Infections, Bunyavirus
Oropouche Orthobunyavirus Infection
Bunyavirus Infections
Orthobunyavirus Infections
Oropouche Infection
Bunyaviridae Infections

Virus diseases caused by the BUNYAVIRIDAE.


RIP Protein
Saporin 6 Protein
SAP5 Protein
Saporin
Ribosome-Inactivating Protein
SAP6 Protein
Saporin Protein
Saporin-S9 Protein
Saporin 5 Protein
Saporins

Type 1 ribosome-inactivating proteins derived from SAPONARIA OFFICINALIS that function through endohydrolysis of the N-glycosidic bond at single ADENOSINE residues of 28S RIBOSOMAL RNA. They are used as IMMUNOTOXINS.


Obidoxime Chloride
Obidoxime
Obidoxim
Toxogonin

Cholinesterase reactivator occurring in two interchangeable isomeric forms, syn and anti.


Zephyrlily Clivia Amaryllidaceae Zephyranthes Cyrtanthus Hippeastrum


Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.


HNF6alpha Transcription Factor
HNF6beta Transcription Factor
HNF6 Transcription Factor
Hepatocyte Nuclear Factor 6-Beta
Hepatocyte Nuclear Factor 6-Alpha
Hepatocyte Nuclear Factor 6

A onecut transcription factor that regulates expression of GENES involved in EMBRYONIC DEVELOPMENT of the PANCREAS and LIVER.


Voice Disturbance
Voice Disorder, Neurologic
Neurologic Voice Disorder
Voice Fatigue
Voice Disorders

Pathological processes that affect voice production, usually involving VOCAL CORDS and the LARYNGEAL MUCOSA. Voice disorders can be caused by organic (anatomical), or functional (emotional or psychological) factors leading to DYSPHONIA; APHONIA; and defects in VOICE QUALITY, loudness, and pitch.


Cyclopropanecarboxylic Acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester

A pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.


Cephapirin Monosodium Salt
BL-P 1322
Cephapirin
Cephapirin Sodium
Brisfirina
Sodium Cephapirin
Céfaloject
Cefadyl
Cefapirin

Cephalosporin antibiotic, partly plasma-bound, that is effective against gram-negative and gram-positive organisms.


Pregnanolone, (3beta, 5alpha, 8alpha, 17beta)-isomer

Pregnanolone, (3alpha, 5beta, 17-alpha)-isomer

Pregnanolone, (3beta, 5beta, 17alpha)-isomer

Pregnanolone, (3beta, 5alpha, 17alpha)-isomer

A pregnane found in the urine of pregnant women and sows. It has anesthetic, hypnotic, and sedative properties.


Humor as Topic
Wit
Wit as Topic
Wit and Humor as Topic

The comical expression of connections between ideas that awaken amusement and pleasure.


Progressive Myoclonus Epilepsy, Lafora Type

Progressive Myoclonic Epilepsy, Lafora Type

Lafora Type Progressive Myoclonic Epilepsy

A form of stimulus sensitive MYOCLONIC EPILEPSY inherited as an autosomal recessive condition. The most common presenting feature is a single seizure in the second decade of life. This is followed by progressive myoclonus, myoclonic seizures, tonic-clonic seizures, focal occipital seizures, intellectual decline, and severe motor and coordination impairments. Most affected individuals do not live past the age of 25 years. Concentric amyloid (Lafora) bodies are found in neurons, liver, skin, bone, and muscle (From Menkes, Textbook of Childhood Neurology, 5th ed, pp111-110).


Secondary Hypothyroidism
Central Hypothyroidism
Thyroid-Stimulating Hormone Deficiency
TSH Deficiency
Primary Hypothyroidism
Hypothyroidism

A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.


Poa
Kentucky Blue Grass
Grass, Kentucky Blue
Bluegrass
Poa pratensis

A plant genus of the family POACEAE that contains the Poa p Ia allergen and allergen C KBGP.


Claw
Claw and Hoof
Hoof
Hoof and Claw
Hooves and Claws
Claws and Hooves
Hooves

Highly keratinized processes that are sharp and curved, or flat with pointed margins. They are found especially at the end of the limbs in certain animals.


Wiskott-Aldrich Syndrome Protein Family, Member 3

Wiskott-Aldrich Syndrome Protein Family, Member 2

WASP-Family Verprolin Homologous Proteins

Wiskott-Aldrich Syndrome Protein Family, Member 1

A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.


Bulbar Palsy
Childhood Progressive Bulbar Palsy
Fazio-Londe Syndrome
Bulbar Palsy, Progressive
Paralysis, Bulbar
Fazio-Londe Disease
Bulbar Palsy, Progressive, Of Childhood
Progressive Bulbar Palsy of Childhood

A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900)


Marburg Virus
Marburgvirus
Frankfurt-Marburg Syndrome Virus
Lake Victoria marburgvirus
Marburg-like Viruses

The type species of MARBURGVIRUS, associated with severe illness in workers handling tissues of African green monkeys.


Disinfection, Hand
Handwashing
Surgical Scrubbing
Scrubbing, Surgical
Hand Sanitization
Hand Washing
Hand Disinfection

The act of cleansing the hands with water or other liquid, with or without the inclusion of soap or other detergent, for the purpose of removing soil or microorganisms.


Nitrogen-linked Glycoside Hydrolases
Nucleoside Hydrolases
Nucleosidases
Hydrolases, N-Glycosyl
Glycoside Hydrolases, Nitrogen-linked
N-Glycosyl Hydrolases

N-GLYCOSYL HYDROLASES that catalyze the hydrolysis of the N-glycosidic bond of nucleoside-linked sugars.


Tomoxetine Hydrochloride, (+)-isomer - T351671

A propylamine derivative and selective ADRENERGIC UPTAKE INHIBITOR that is used in the treatment of ATTENTION DEFICIT HYPERACTIVITY DISORDER.


5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation.


Smoking Ban
Smoking Prohibition
Smoke-Free Policy

Prohibition against tobacco smoking in specific areas to control TOBACCO SMOKE POLLUTION.


Common Foxglove
Grecian Foxglove
Digitalis
Digitalis purpurea
Foxglove
Digitalis lanata

A genus of toxic herbaceous Eurasian plants of the Plantaginaceae which yield cardiotonic DIGITALIS GLYCOSIDES. The most useful species are Digitalis lanata and D. purpurea.


SFC (Supercritical Fluid Chromatography)

A CHROMATOGRAPHY method using supercritical fluid, usually carbon dioxide under very high pressure (around 73 atmospheres or 1070 psi at room temperature) as the mobile phase. Other solvents are sometimes added as modifiers. This is used both for analytical (SFC) and extraction (SFE) purposes.


Gingival Atrophy
Gingival Recession
Atrophy of Gingiva

Exposure of the root surface when the edge of the gum (GINGIVA) moves apically away from the crown of the tooth. This is common with advancing age, vigorous tooth brushing, diseases, or tissue loss of the gingiva, the PERIODONTAL LIGAMENT and the supporting bone (ALVEOLAR PROCESS).


A pyrazole and piperidine derivative that acts as a selective cannabinoid type-1 receptor (CB1 RECEPTOR) antagonist. It inhibits the proliferation and maturation of ADIPOCYTES, improves lipid and glucose metabolism, and regulates food intake and energy balance. It is used in the management of OBESITY.


Antagonists, Histamine H1 Receptor
H1 Receptor Blockaders
Histamine H1 Antagonists
First Generation H1 Antagonists
Antihistaminics, Classical
Antihistamines, Sedating
Histamine H1 Blockers
Antihistaminics, H1
Histamine H1 Receptor Blockaders
Receptor Blockaders, H1
Antihistamines, Classical
Antagonists, Histamine H1
Histamine H1 Receptor Antagonists
Blockaders, Histamine H1 Receptor

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.


Mouse, Transgenic
Mice, Transgenic
Mouse, Founder, Transgenic
Founder Mice, Transgenic
Transgenic Mice

Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.


Poppy
Papaver somniferum
Papaver
Opium Poppy

A genus of Eurasian herbaceous plants, the poppies (family PAPAVERACEAE of the dicotyledon class Magnoliopsida), that yield OPIUM from the latex of the unripe seed pods.


Pachyonychia Congenita Jackson Lawler Type

Pachyonychia Congenita, Jadassohn-Lewandowsky Type

Pachyonychia Congenita, Jackson-Lawler Type

Jackson-Lawler Type Pachyonychia Congenita

A subtype of pachyonychia congenita that is associated with mutations in the gene for KERATIN-16 and the gene for KERATIN-6A.


A carboline derivative and PHOSPHODIESTERASE 5 INHIBITOR that is used primarily to treat ERECTILE DYSFUNCTION; BENIGN PROSTATIC HYPERPLASIA and PRIMARY PULMONARY HYPERTENSION.


Chromosome Instability
Chromosomal Instability
Chromosomal Stability
Chromosome Stability

An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.


Anti-Apoptotic Proteins
Survival Factors (Apoptosis)
Apoptosis Regulatory Proteins
Apoptosis Inhibiting Proteins
Death Factors (Apoptosis)
Apoptosis Inducing Proteins
Pro-Apoptotic Proteins
Programmed Cell Death Proteins

A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS such as CASPASES.


Difficulty Ambulation
Ambulation Difficulty
Mobility Limitation
Ambulatory Difficulty
Difficulty Walking

Difficulty in walking from place to place.


Wheelchair Athletes
Paralympian
Para Athletes
Para-Athlete
Para-Athletes
Paralympians
Paralympic Athletes

Physically disabled individuals who have developed skills, physical stamina and strength to participate in SPORTS or other physical activities.


An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.


Rhythm Method of Family Planning, Temperature

Rhythm Method of Family Planning, Calendar

Rhythm Method of Family Planning, Cervical Mucus

A class of natural contraceptive methods in which SEXUAL ABSTINENCE is practiced a few days before and after the estimated day of ovulation, during the fertile phase. Methods for determining the fertile period or OVULATION DETECTION are based on various physiological indicators, such as circulating hormones, changes in cervical mucus (CERVIX MUCUS), and the basal body temperature.


Broncholytic Agents
Bronchodilator Effects
Bronchial-Dilating Agents
Broncholytic Effect
Bronchodilator Agents
Broncholytic Effects
Bronchodilators
Bronchodilator Effect

Agents that cause an increase in the expansion of a bronchus or bronchial tubes.


Congenital Coxa Valgus
Congenital Coxa Valga
Coxa Valgus
Coxa Valga
Acquired Coxa Valgus
Developmental Coxa Valga
Acquired Coxa Valga
Developmental Coxa Valgus

Hip deformity in which the angle between the femoral neck and its shaft is increased. It may be congenital, acquired, or developmental.


Teaching Methods
Pedagogy
Academic Training
Training Techniques
Educational Techniques
Training Activities
Techniques, Educational
Training Technics
Teaching
Educational Technics
Technics, Educational


Plasminogen Activator Inhibitors, Endothelial

Plasminogen Activator Inhibitors, Placental

Endothelial Plasminogen Activator Inhibitors

Placental Plasminogen Activator Inhibitors

Important modulators of the activity of plasminogen activators. The inhibitors belong to the serpin family of proteins and inhibit both the tissue-type and urokinase-type plasminogen activators.


A thienamycin derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of bacterial infections, including infections in immunocompromised patients.


Calcium Binding Protein, Vitamin D Dependent

Vitamin D-Dependent Calcium-Binding Protein

Intestinal Membrane Calcium-Binding Protein

Calcium-Binding Protein, Vitamin D-Dependent

A subtype of S100 calcium binding protein G found in intestine.


Humalanes
Cyclofarnesane Derivatives
Elemane Derivatives
Humalane Derivatives
Bisabolanes
Cyclofarnesanes
Bisabolane Derivatives
Monocyclic Sesquiterpenes
Elemanes

Sesquiterpene compounds that contain a single ring structure.


Ethiodized Oils
Ethiodized Poppy Seed Oil
Ethiodol
Ethiodized Oil
Lipiodol
Ethiodized Oil (Injection)
Lipiodol UltraFluid

Ethyl ester of iodinated fatty acid of poppyseed oil. It contains 37% organically bound iodine and has been used as a diagnostic aid (radiopaque medium) and as an antineoplastic agent when part of the iodine is 131-I. (From Merck Index, 11th ed)


Sinus Node Dysfunction
Sick Sinus Node Syndrome
Sinus Node Disease
Sick Sinus Syndrome

A condition caused by dysfunctions related to the SINOATRIAL NODE including impulse generation (CARDIAC SINUS ARREST) and impulse conduction (SINOATRIAL EXIT BLOCK). It is characterized by persistent BRADYCARDIA, chronic ATRIAL FIBRILLATION, and failure to resume sinus rhythm following CARDIOVERSION. This syndrome can be congenital or acquired, particularly after surgical correction for heart defects.


3D-Mammography
Digital Breast Tomosynthesis
X-ray Breast Tomosynthesis
Mammography
Digital Mammography


Syzygium cumini
Eugenia jambos
Caryophyllus aromaticus
Eugenia aromatica
Syzygium
Eugenia caryophyllata
Eugenia sandwicensis
Syzygium malaccense
Java Plum Tree
Eugenia cumini
Syzygium aromaticum
Eugenia jambolana
Eugenia malaccensis
Syzygium jambolanum
Caryophyllus
Syzygium sandwicense
Cleistocalyx
Clove
Jambolan Plum Tree
Syzygium jambos

A plant genus in the family Myrtaceae. It is known for cloves, which is the flower bud of Syzygium aromaticum and is the source of an oil rich in EUGENOL.


Leukodystrophy, Globoid Cell, Early-Onset

Leukodystrophy, Globoid Cell, Late-Onset

An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses.


State-of-the-Art Reviews
Review Literature as Topic
State-of-the-Art Review

Works about published materials which provide an examination of recent or current literature. These articles can cover a wide range of subject matter at various levels of completeness and comprehensiveness based on analyses of literature that may include research findings. The review may reflect the state of the art and may also include reviews as a literary form.


Patchy Particles
Janus Particles
Janus Nanoparticles
Two-Faced Nanoparticles
Multifunctional Nanoparticles

Nanoparticles that are engineered to have two or more physical properties.


Outpatient Health Services
Services, Outpatient Health
Clinic Visits
Outpatient Care
Ambulatory Care
Outpatient Services
Urgent Care
Health Services, Outpatient

Health care services provided to patients on an ambulatory basis, rather than by admission to a hospital or other health care facility. The services may be a part of a hospital, augmenting its inpatient services, or may be provided at a free-standing facility.


Prosthetic Implants
Endoprosthesis
Prostheses
Implants, Artificial
Endoprostheses
Prosthesis
Prostheses and Implants

Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.


X-Linked Familial Exudative Vitreoretinopathy

A group of inherited disorders characterized by incomplete development of the retinal vasculature. Its severity can vary from complete blindness in infancy, to mild or no visual problems, where small areas of vascular defects are observable only by FLUORESCEIN ANGIOGRAPHY. Exudative vitreoretinopathy 1 is associated with mutations in the FZD4 gene.


Women's Role
Men's Role
Sex Role
Gender Identity
Gender
Man's Role
Woman's Role
Gender Role

Socially-constructed identity of male or female.


Metabolic Side Effects of Drugs and Substances

Specific effects of drugs and substances on metabolic pathways such as those occurring through the CYTOCHROME P-450 ENZYME SYSTEM. These include effects that often result in DRUG INTERACTIONS; FOOD-DRUG INTERACTIONS; and HERB-DRUG INTERACTIONS.


NKT Cells
iNKT Cells
Natural Killer T-Cell
Invariant Natural Killer T-Cells
Natural Killer T-Cells
NKT Cell

A specific natural killer T-cell subtype that expresses an invariant T-cell receptor alpha-chain.


Cutaneous Administration, Drug
Dermal Administration
Administration, Transdermal
Skin Administration, Drug
Dermal Drug Administration
Transcutaneous Administration
Cutaneous Administration
Drug Administration, Cutaneous
Administration, Transcutaneous
Percutaneous Administration
Administration, Cutaneous
Cutaneous Drug Administration
Drug Administration, Dermal
Administration, Dermal
Skin Drug Administration
Transdermal Administration

The application of suitable drug dosage forms to the skin for either local or systemic effects.


Sex Organs, Accessory, Male
Reproductive System, Male
Accessory Sex Organs, Male
Genitalia, Male
Genitals, Male
Genital Organs, Male

The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM; and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).


Altace Carasel Ramace Acovil Ramipril HOE-498 Delix Tritace Zabien Triatec Vesdil

A long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.


Platelet Glycoprotein IIIa
beta3C Integrin
CD61 Antigen
beta3A Integrin
Platelet GPIIIa
GPIIIa
Integrin beta3
Integrin beta3B
Integrin beta3A
beta3B Integrin
CD61 Antigens
beta3 Integrin
beta(3) Integrin
Platelet Membrane Glycoprotein IIIa
Antigens, CD61
Integrin beta3C

An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.


Brazilian Pine
Araucaria augustifolia
Araucaria

A species of conifers commonly referred to as "pine", but does not belong in the genus Pinus. Araucaria augustifolia is widely distributed in Brazil and Argentina.


Cloning
Cloning, Human
Human Cloning
Cloning, Organism
Embryo Cloning
Cloning, Embryo

The formation of one or more genetically identical organisms derived by vegetative reproduction from a single cell. The source nuclear material can be embryo-derived, fetus-derived, or taken from an adult somatic cell.


Extracorporeal High-Intensity Focused Ultrasound Therapy

A nonsurgical treatment that uses either HIGH-ENERGY SHOCK WAVES or low energy ACOUSTIC WAVES to treat various musculoskeletal conditions (e.g., PLANTAR FASCIITIS; TENNIS ELBOW). A probe placed on the skin conducts the shock waves thereby delivering a mechanical force to the body’s tissues.


Trichothiodystrophy with Congenital Ichtyosis

Ichthyosiform Erythroderma with Hair Abnormality and Mental and Growth Retardation

Brittle Hair-Intellectual Impairment-Decreased Fertility-Short Stature Syndrome

Ichthyosis, Brittle Hair, Intellectual Impairment, Decreased Fertility, and Short Stature

Autosomal recessive neuroectodermal disorders characterized by brittle sulfur-deficient hair associated with impaired intellect, decreased fertility, and short stature. It may include nail dystrophy, ICHTHYOSIS, and photosensitivity correlated with a NUCLEOTIDE EXCISION REPAIR defect. All individuals with this disorder have a deficiency of cysteine-rich KERATIN-ASSOCIATED PROTEINS found in the interfilamentous matrix. Photosensitive trichothiodystrophy can be caused by mutation in at least 2 separate genes: ERCC2 PROTEIN gene and the related ERCC3. Nonphotosensitive trichothiodystrophy can be caused by mutation in the TTDN1 gene.


Botulinum Toxins, Type A
Vistabex
Oculinum
Clostridium botulinum A Toxin
Clostridium Botulinum Toxin Type A
OnabotulinumtoxinA
Botulinum Toxin Type A
Botulinum A Toxin
Vistabel
Meditoxin
Botox
Neuronox
Onabotulinumtoxin A
Botulinum Neurotoxin A

A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.


Puma
Mountain Lion
Puma concolor coryi
Puma concolor
Felis concolor
Cougars
Florida Panther


Antibiotics, Antineoplastic
Antibiotics, Cytotoxic
Antineoplastic Antibiotics
Cytotoxic Antibiotics

Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms.


An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.


Charcot-Marie-Tooth Disease, Autosomal Dominant, with Focally Folded Myelin Sheaths, Type 1B

Hereditary Motor, and Sensory Neuropathy Type I

Hereditary Motor And Sensory Neuropathy IB

Hereditary Motor and Sensory-Neuropathy Type II

Neuropathy, Type I Hereditary Motor and Sensory

Charcot-Marie-Tooth Disease, Slow Nerve Conduction Type, Linked To Duffy

Charcot-Marie-Tooth Disease, Autosomal Dominant, With Focally Folded Myelin Sheaths, Type 1A

Charcot-Marie-Tooth Disease, Demyelinating, Type 1A

Hereditary Motor and Sensory Neuropathy 1B

Roussy-Levy Hereditary Areflexic Dystasia

Roussy Levy Hereditary Areflexic Dystasia

Charcot-Marie-Tooth Disease, Demyelinating, Type 1B

Neuropathy, Type II Hereditary Motor and Sensory

Hereditary Type I Motor and Sensory Neuropathy

Hereditary Motor and Sensory Neuropathy 1A

Hereditary Motor and Sensory Neuropathy IA

A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)


T-Cell Receptor gamma-Chain
T-Cell Receptor, gamma-delta
Antigen T Cell Receptor, delta Chain
T-Cell Receptors, gamma-delta
T-Cell Receptors gamma-Chain
T Cell Receptors, gamma delta
T-Cell Receptors delta-Chain
Receptors, Antigen, T Cell, gamma delta
TcR gamma-delta
Antigen T Cell Receptor, gamma Chain
Antigen Receptors, T-Cell, gamma-delta
T-Cell Receptor delta-Chain
Receptors, Antigen, T-Cell, gamma-delta

T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3).


Contrast Media
Contrast Agents
Contrast Material
Contrast Agent
Radiopaque Media
Contrast Materials
Radiocontrast Agent
Radiocontrast Media
Radiocontrast Agents

Substances used to allow enhanced visualization of tissues.


False Aneurysm, Carotid
Trauma, Carotid Artery
Carotid False Aneurysm
Carotid Arteriopathies, Traumatic
Carotid Artery Injuries
Carotid Pseudoaneurysm
Injuries, Carotid Artery

An acquired abnormality resulting from leaked blood from damaged CAROTID ARTERIES, often due to TRAUMA or INFECTION. The leaked blood is contained in the surrounding tissues and forms a pulsatile neck mass.


T-Cell Receptors beta-Chain
T-Cell Receptor, alpha-beta
T-Cell Receptors, alpha-beta
Antigen T Cell Receptor, alpha Chain
TcR alpha-beta
Receptors, Antigen, T-Cell, alpha-beta
T-Cell Receptor alpha-Chain
T-Cell Receptor beta-Chain
T-Cell Receptors alpha-Chain
Antigen T Cell Receptor, beta Chain
T Cell Receptors, alpha beta
Receptors, Antigen, T Cell, alpha beta
Antigen Receptors, T-Cell, alpha-beta

T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.


Patient Advocacy
Patient Representatives
Patient Ombudsmen
Patient Ombudsman
Clinical Ombudsman

Promotion and protection of the rights of patients, frequently through a legal process.


Olacaceae
Ochanostachys
Muira Puama
Schoepfia
Ximenia
Ptychopetalum

A plant genus. Members contain muirapuamine.


Cannabis Dependence
Marijuana Abuse
Hashish Abuse
Marijuana Dependence
Cannabis Abuse
Cannabis-Related Disorder
Marihuana Abuse

Use of marijuana associated with abnormal psychological, social, and or occupational functioning.


Dendroaspis angusticeps
Dendroaspis jamesoni
Dendroaspis
Black Mamba
Dendroaspis viridis
Mamba
Green Mamba
Jameson's Mamba
Eastern Green Mamba
Dendroaspis polylepis

A genus of highly venomous elapid snake indigenous to sub-Saharan Africa.


X-ray Repair Cross-Complementing Protein 6

X-ray Repair Cross-Complementing Protein 5

An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.


Clotting Protein (Seminal Vesicle)
Clotting Proteins (Seminal Vesicle)
Seminal Vesicle Clotting Proteins
Seminal Vesicle Secretory Proteins
Seminal Vesicle Clotting Protein
Seminal Vesicle Proteins

The secretory proteins of the seminal vesicles are proteins and enzymes that are important in the rapid clotting of the ejaculate. The major clotting protein is seminal vesicle-specific antigen. Many of these seminal vesicle proteins are under androgen regulation, and are substrates for the prostatic enzymes, such as the PROSTATE-SPECIFIC ANTIGEN, a protease and an esterase.


Nuchal Translucency Screening
Nuchal Fold Measurement
Nuchal Translucency Measurement
Nuchal Translucency
Nuchal Fold Screening
Nuchal Fold

A prenatal ultrasonography measurement of the soft tissue behind the fetal neck. Either the translucent area below the skin in the back of the fetal neck (nuchal translucency) or the distance between occipital bone to the outer skin line (nuchal fold) is measured.


Fish Antifreeze Proteins, Type IV
Fish Type IV AFP
Type IV Antifreeze Proteins
Antifreeze Proteins, Type IV
Type IV Fish Antifreeze Proteins

A subclass of ANTIFREEZE PROTEINS that contain four amphipathic alpha-helices folded into an antiparallel helix bundle.


Tilapia
Oreochromis mossambicus
Tilapia mossambica
Mozambique Tilapia

A freshwater fish used as an experimental organism and for food. This genus of the family Cichlidae (CICHLIDS) inhabits Central and South America (one species extends north into Texas), West Indies, Africa, Madagascar, Syria, and coastal India.


Low-Copy Repeats, DNA
Segmental Duplications, Genomic
Segmental Duplications
Low-Copy Repeat Sequences
Low-Copy Repeats
Duplicons

Low-copy (2-50) repetitive DNA elements that are highly homologous and range in size from 1000 to 400,000 base pairs.


Waste Dumping Grounds
Landfills
Waste Disposal Facilities
Waste Disposal Sites
Waste Dump Sites
Waste Dumps
Waste Dumping Sites

Locations where WASTE PRODUCTS are buried in dirt.


Neoplasms, Esophageal
Esophageal Cancer
Esophageal Neoplasms
Cancer of Esophagus
Cancer of the Esophagus
Esophagus Neoplasm
Esophagus Cancer


Trombovar
Tergitol 4
Sotradecol
Sotradecol Sodium
Trombavar
Sodium Tetradecyl Sulfate

An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.


Surgical Staples
Staples, Surgical
Staple, Surgical
Surgical Staple
Sutures

Materials used in closing a surgical or traumatic wound. (From Dorland, 28th ed)


Cavities, Dental Pulp
Dental Pulp Cavity
Pulp Cavities, Dental
Pulp Chamber
Dental Pulp Cavities
Pulp Canal
Root Canal
Cavity, Dental Pulp
Pulp Cavity, Dental

The space in a tooth bounded by the dentin and containing the dental pulp. The portion of the cavity within the crown of the tooth is the pulp chamber; the portion within the root is the pulp canal or root canal.


Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS.


Mud Therapy
Peat Therapy
Therapy, Mud
Therapy, Peat
Mud Baths
Fangotherapy
Mud Packs
Pelotherapy
Peloid Therapy
Therapy, Peloid

Fango refers to a volcanic mud in Italy.


Intensity-Modulated Arc Therapy
Radiotherapy, Intensity-Modulated
Helical Tomotherapy
Volumetric-Modulated Arc Therapy

An arc-based approach to the delivery of intensity-modulated radiotherapy that uses a fan-beam of radiation in conjunction with a binary multileaf collimator.


Leukoplasts Plastids Leucoplasts Amyloplasts Chromoplasts

Plastids containing carotenoid pigments.


Nervus Facialis
Nervus Intermedius
Seventh Cranial Nerve
Marginal Mandibular Branch
Cranial Nerve VII
Marginal Mandibular Nerve
Nerve of Wrisberg
Facial Nerve
Nervus Intermedius of Wrisberg
Nerve VII

The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and SALIVARY GLANDS, and convey afferent information for TASTE from the anterior two-thirds of the TONGUE and for TOUCH from the EXTERNAL EAR.


A plant species of the family FABACEAE that yields edible seeds called peanuts, which contain protein, oil, and lectins. Peanuts are also known as groundnuts which is a name also used for the edible seeds or edible PLANT ROOTS of other genera such as Apios, Vigna, Conopodium, or Macrotyloma.


Ligamentum Teres
Round Ligaments
Oblique Cord
Chorda Obliqua
Round Ligament of Elbow
Round Ligament

Cord shaped ligament found spanning between the ULNAR and RADIUS bones near the ELBOW JOINT.


Sampling Error
Selection Bias
Bias, Selection
Selection Biases
Sampling Bias
Sampling Biases

The introduction of error due to systematic differences in the characteristics between those selected and those not selected for a given study. In sampling bias, error is the result of failure to ensure that all members of the reference population have a known chance of selection in the sample.


Anosmia
Cacosmia
Paraosmia
Smell Disorders
Olfaction Disorders
Dysosmia

Absence of the sense of smell. (Dorland, 27th ed)


Deaf-Mutism
Hearing Loss Permanent
Deafness
Deafness Permanent
Hearing Loss, Extreme
Deafness, Acquired
Hearing Loss, Complete
Deaf Mutism
Prelingual Deafness

A general term for the complete loss of the ability to hear from both ears.


alpha-Calcitonin Gene-Related Peptide
Calcitonin Gene-Related Peptide
alpha-CGRP
beta-CGRP
beta-Calcitonin Gene-Related Peptide
Calcitonin Gene-Related Peptide II
Calcitonin Gene-Related Peptide I

A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.


Myelomeningocele
Myelocele
Myelomeningocele, Acquired
Acquired Meningomyelocele
Meningomyelocele

Congenital, or rarely acquired, herniation of meningeal and spinal cord tissue through a bony defect in the vertebral column. The majority of these defects occur in the lumbosacral region. Clinical features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with the ARNOLD-CHIARI MALFORMATION and HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6)


Fosfomycin
Fosfomycin Tromethamine
Monuril
Phosphomycin
Fosfomycin Trometamol Salt
Phosphonomycin

An antibiotic produced by Streptomyces fradiae.


Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type

Extranodal NK-T-Cell Lymphoma, Nasal Type

An extranodal neoplasm, usually possessing an NK-cell phenotype and associated with EPSTEIN-BARR VIRUS. These lymphomas exhibit a broad morphologic spectrum, frequent necrosis, angioinvasion, and most commonly present in the midfacial region, but also in other extranodal sites.


Sonic Radiation
Sound Waves
Acoustic Waves
Sound
Elastic Waves

A type of non-ionizing radiation in which energy is transmitted through solid, liquid, or gas as compression waves. Sound (acoustic or sonic) radiation with frequencies above the audible range is classified as ultrasonic. Sound radiation below the audible range is classified as infrasonic.


Tubulin Polymerization Inhibitors
Tubulin Polymerization Promoters
Tubulin Promoters
Tubulin Inhibitors
Tubulin Modulators
Microtubule Modulators

Agents that interact with TUBULIN to inhibit or promote polymerization of MICROTUBULES.


Modified Immune Globulin (Anti-Echovirus Antibody)

Immunoglobulins obtained from human serum for the purpose of intravenous administration.


Heat-Stress Response
Heat-Shock Reaction
Heat Shock
Heat Shock Stress
Heat-Stress Reaction
Heat Stress
Heat-Shock Response

A sequence of responses that occur when an organism is exposed to excessive heat. In humans, an increase in skin temperature triggers muscle relaxation, sweating, and vasodilation.


Ethidium Bromide
Ethidium
Homidium Bromide
Novidium

A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide.


An HIV protease inhibitor that works by interfering with the reproductive cycle of HIV. It also inhibits CYTOCHROME P-450 CYP3A.


A tetrahydronaphthalene derivative and RETINOID X RECEPTOR antagonist that is used in the treatment of CUTANEOUS T-CELL LYMPHOMA.


Electrophorus electricus
Electrophorus
Eel, Electric
Electric Eel

A genus of fish, in the family GYMNOTIFORMES, capable of producing an electric shock that immobilizes fish and other prey. The species Electrophorus electricus is also known as the electric eel, though it is not a true eel.


Finkel-Biskis-Jinkins murine sarcoma virus

Finkel-Biskis-Reilly murine sarcoma virus

A group of replication-defective viruses, in the genus GAMMARETROVIRUS, which are capable of transforming cells, but which replicate and produce tumors only in the presence of Murine leukemia viruses (LEUKEMIA VIRUS, MURINE).


An inhibitor of drug metabolism and CYTOCHROME P-450 ENZYME SYSTEM activity.


Sphincterotomy, Transduodenal
Sphincterotomy, Transhepatic
Sphincteroplasty, Transhepatic
Sphincteroplasty, Transduodenal

Surgical incision of the SPHINCTER OF ODDI in the management of COMMON BILE DUCT DISEASES (e.g., CHOLEDOCHOLITHIASIS; and SPHINCTER OF ODDI DYSFUNCTION).


Encephalomyelitis Virus, Porcine Hemagglutinating

The type species of BETACORONAVIRUS genus causing gastroenteritis respiratory diseases in mammals. Previously separate species HUMAN CORONAVIRUS OC43; BOVINE CORONAVIRUS; Human enteric coronavirus; Equine coronavirus; and Porcine hemagglutinating encephalomyelitis virus merged into this species on the basis of similar genome nucleotide sequence and genome organization.


Levalbuterol
Xopenex
Levosalbutamol Hydrochloride
Levalbuterol Hydrochloride


Kappa Casein Kinase
Casein Kinase 1
Protein Kinase CKI
Casein Kinase Igamma
Casein Kinase Ikappa
Protein Kinase CK1
Casein Kinase Itau
Casein Kinase I
tau Casein Kinase I
Casein Kinase Ibeta

A casein kinase that was originally described as a monomeric enzyme with a molecular weight of 30-40 kDa. Several ISOENZYMES of casein kinase I have been found which are encoded by separate genes. Many of the casein kinase I isoenzymes have been shown to play distinctive roles in intracellular SIGNAL TRANSDUCTION.


X-Ray Absorption Near Edge Structure Spectroscopy

X-Ray Absorption Near-Edge Structure Spectroscopy

Near-Edge X-Ray Absorption Fine Structure Spectroscopy

Near Edge X-Ray Absorption Fine Structure Spectroscopy

Analysis of the oscillations observed in an x-ray absorption spectrum that begin just above the absorption edge (i.e. the point on the spectrum where the amount of x-ray absorption suddenly increases) to determine or evaluate the chemical structure of the absorbing surface.


Disease-Modifying, Antirheumatic Second-Line Drugs

Antirheumatic Disease-Modifying Second-Line Drugs

Drugs that are used to treat RHEUMATOID ARTHRITIS.


Serine Palmitoyltransferase, Long Chain Base Subunit 2

Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating)

Serine Palmitoyltransferase, Long Chain Base Subunit 1

A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.


Desmoplakin I
Desmoplakins
Desmoplakin
Desmoplakin 2
Desmoplakin 1
Desmoplakin II

Desmoplakins are cytoskeletal linker proteins that anchor INTERMEDIATE FILAMENTS to the PLASMA MEMBRANE at DESMOSOMES.


Fertility Drugs
Infertility Drugs
Fertility Effects
Infertility Effect
Infertility Agents
Fertility Effect
Fertility Agents
Infertility Effects

Drugs used to increase fertility or to treat infertility.


Pineal Parenchymal Tumors
Mixed Pineocytoma-Pineoblastoma
Pineal Gland Tumor
Neoplasms, Pineal
Pineocytoma
Pinealoma
Pineal Tumors
Pineoblastoma
Pineal Neoplasms
Pinealocytoma

Neoplasms which originate from pineal parenchymal cells that tend to enlarge the gland and be locally invasive. The two major forms are pineocytoma and the more malignant pineoblastoma. Pineocytomas have moderate cellularity and tend to form rosette patterns. Pineoblastomas are highly cellular tumors containing small, poorly differentiated cells. These tumors occasionally seed the neuroaxis or cause obstructive HYDROCEPHALUS or Parinaud's syndrome. GERMINOMA; CARCINOMA, EMBRYONAL; GLIOMA; and other neoplasms may arise in the pineal region with germinoma being the most common pineal region tumor. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2064; Adams et al., Principles of Neurology, 6th ed, p670)


Sand Baths
Ammotherapy
Baths, Sand
Sandbaths


2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-,1- azabicyclo(2.2.2)oct-3-yl ester, (R-(R*,S*))-

A quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.


Dimethylarsinic Acid
Cacodylic Acid
Cacodylate
Dimethylarsinate

An arsenical that has been used as a dermatologic agent and as an herbicide.


Immunoblot, Western
Blot, Western
Blotting, Western
Western Immunoblot
Western Blot
Western Blotting
Immunoblotting, Western
Western Immunoblotting

Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.


Calcium Oxalate Dihydrate
Calcium Oxalate Monohydrate
Calcium Oxalate Monohydrate (1:1)
Calcium Oxalate
Calcium Oxalate (1:1)
Calcium Oxalate Trihydrate
Calcium Oxalate Dihydrate (1:1)

The calcium salt of oxalic acid, occurring in the urine as crystals and in certain calculi.


Multiple Acyl Coenzyme A Dehydrogenase Deficiency

MADD (Multiple Acyl-CoA Dehydrogenase Deficiency)

Electron Transfer Flavoprotein Dehydrogenase Deficiency

Electron Transfer Flavoprotein Deficiency

Electron Transfer Flavoprotein Beta Subunit Deficiency

Electron Transfer Flavoprotein Alpha Subunit Deficiency

An autosomal recessive disorder of fatty acid oxidation, and branched chain amino acids (AMINO ACIDS, BRANCHED-CHAIN); LYSINE; and CHOLINE catabolism, that is due to defects in either subunit of ELECTRON TRANSFER FLAVOPROTEIN or its dehydrogenase, electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1).


alpha-Amylase Inhibitors, Pancreatic
Pancreatic alpha-Amylase Inhibitors
Intestinal alpha-Amylase Inhibitors
alpha-Glucosidase Inhibitors
Glycoside Hydrolase Inhibitors

Compounds that inhibit ALPHA-GLUCOSIDASE.


Peptide Elongation Factor Tu
Elongation Factor Tu
Eucaryotic Elongation Factor Tu
Protein Synthesis Elongation Factor Tu
EF-Tu
eEF-Tu

A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.


Luminescence, Physical
Luminescence
Chemiluminescence
Chemiluminescence, Physical

Emission of LIGHT when ELECTRONS return to the electronic ground state from an excited state and lose the energy as PHOTONS. It is sometimes called cool light in contrast to INCANDESCENCE. LUMINESCENT MEASUREMENTS take advantage of this type of light emitted from LUMINESCENT AGENTS.


P2X7 Purinoceptor Antagonists
Purinergic P2X5 Receptor Antagonists
Purinergic P2X7 Receptor Antagonists
Purinergic P2X Receptor Antagonists
P2X5 Purinoceptor Antagonists
P2X Purinoceptor Antagonists
P2X1 Purinoceptor Antagonists
P2X3 Purinoceptor Antagonists
Purinergic P2X3 Receptor Antagonists
Purinergic P2X2 Receptor Antagonists
P2X4 Purinoceptor Antagonists
Purinergic P2X4 Receptor Antagonists
P2X6 Purinoceptor Antagonists
Purinergic P2X1 Receptor Antagonists
P2X2 Purinoceptor Antagonists
Purinergic P2X6 Receptor Antagonists

Compounds that bind to and block the stimulation of PURINERGIC P2X RECEPTORS. Included under this heading are antagonists for specific P2X receptor subtypes.


Transient Ischemic Attack, Vertebrobasilar Circulation

Vertebrobasilar Circulation Transient Ischemic Attack

Transient Ischemic Attack, Posterior Circulation

Transient Ischemic Attack, Carotid Circulation

Posterior Circulation Transient Ischemic Attack

Anterior Circulation Transient Ischemic Attack

Transient Ischemic Attack, Anterior Circulation

Carotid Circulation Transient Ischemic Attack

Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)


Leukemia, Lymphoblastic, Acute, Philadelphia-Positive

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Lymphoblastic Leukemia, Acute, Childhood

When the disease process is confined to a mass lesion with no or minimal evidence of blood and less than 25% marrow involvement, the diagnosis is lymphoblastic lymphoma; with blood and greater than 25% marrow involvement, ALL is the appropriate term.


Mafenide
Bensulfamide
Napaltan
4-Homosulfanilamide
Sulfabenzamine
Mafylon
Mafenide Acetate
Marfanil
Sulfamylon
Maphenid

A sulfonamide that inhibits the enzyme CARBONIC ANHYDRASE and is used as a topical anti-bacterial agent, especially in burn therapy.


Sequential Organ Failure Assessment Scores

Ratings that express in numerical values the degree of impairment or abnormality in the function of specific organs.


A chelating agent used as an antidote to heavy metal poisoning.


Epidermolysis Bullosa Junctionalis, Herlitz Type

Herlitz-Pearson Type Epidermolysis Bullosa

Epidermolysis Bullosa, Junctional, Herlitz-Pearson Type

Epidermolysis Bullosa, Junctional, Herlitz Type

Epidermolysis Bullosa Junctionalis, Progressive

Epidermolysis Bullosa, Generalized Atrophic Benign

Epidermolysis Bullosa Junctionalis, Severe Nonlethal

Epidermolysis Bullosa Junctionalis, Disentis Type

Form of epidermolysis bullosa having onset at birth or during the neonatal period and transmitted through autosomal recessive inheritance. It is characterized by generalized blister formation, extensive denudation, and separation and cleavage of the basal cell plasma membranes from the basement membrane.


Aurothioglucose, Sodium Salt, beta-D Isomer

A thioglucose derivative used as an antirheumatic and experimentally to produce obesity in animals.


Insulin Receptor Protein-Tyrosine Kinase

Insulin-Dependent Tyrosine Protein Kinase

A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.


Sodium Channel, Voltage-Gated, Type V, alpha Subunit

Voltage-Gated Sodium Channel Type 5 Subunit alpha

Sodium Channel Protein Type 5 Subunit alpha

A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.


Chronically Ill, Dentistry
Dentistry for Chronically Ill
Dental Care for Chronically Ill
Chronically Ill, Dental Care

Dental care for patients with chronic diseases. These diseases include chronic cardiovascular, endocrinologic, hematologic, immunologic, neoplastic, and renal diseases. The concept does not include dental care for the mentally or physically disabled which is DENTAL CARE FOR DISABLED.


A plant genus of the family FABACEAE. Many species of this genus, including the medicinal C. senna and C. angustifolia, have been reclassified into the Senna genus (SENNA PLANT) and some to CHAMAECRISTA.


Neomycin B Sulfate
Framycetin
Soframycin
Framycetin Sulfate
Neomycin B
Antibiotic 10676

A component of NEOMYCIN that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)


Computer Hardware
Calculators, Programmable
Computers, Digital
Computers
Hardware, Computer

Programmable electronic devices designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations.


Nerve Sheath Tumors, Peripheral
Tumors of the Nerve Sheath
Perineurioma
Peripheral Nerve Sheath Tumors
Neoplasms, Nerve Sheath
Nerve Sheath Neoplasms
Nerve Sheath Tumors

Neoplasms which arise from nerve sheaths formed by SCHWANN CELLS in the PERIPHERAL NERVOUS SYSTEM or by OLIGODENDROCYTES in the CENTRAL NERVOUS SYSTEM. Malignant peripheral nerve sheath tumors, NEUROFIBROMA, and NEURILEMMOMA are relatively common tumors in this category.


Crohn's Enteritis
Enteritis, Regional
Regional Enteritis
Crohn Disease
Crohn's Disease
Enteritis, Granulomatous
Ileitis, Terminal
Inflammatory Bowel Disease 1
Ileitis, Regional
Colitis, Granulomatous
Ileocolitis

A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.


Airway Extubation
Tracheal Extubation
Extubation, Intratracheal
Endotracheal Extubation

Removal of an endotracheal tube from the patient.


Cobra Venom
Elapid Venom
Hydrophid Venom
Ophiophagus hannah Venom
Hydrophid Venoms
Cobra Venoms
Naja Venoms
Sea Snake Venoms
King Cobra Venom
Elapid Venoms
Naja Venom
Sea Snake Venom

Venom of the king cobra snake (OPHIOPHAGUS HANNAH) that consists primarily of neurotoxins.


2,3-Dehydrosilybin
Alepa-forte
Lagosa
Hepar-Pasc
Durasilymarin
Legalon Forte
Silybin
Hepa-Merz Sil
Heplant
Silybin A
Hepa-loges
Cefasilymarin
Silybinin
Ardeyhepan
Silibinin
Silibinin A
Heparsyx
Silybin B
HepaBesch
Silibinin B
Silibin

The major active component of silymarin flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum; it is used in the treatment of HEPATITIS; LIVER CIRRHOSIS; and CHEMICAL AND DRUG INDUCED LIVER INJURY, and has antineoplastic activity; silybins A and B are diastereomers.


Social Characteristics
Sociological Factors
Sociological Characteristics
Sociological Phenomena
Social Attributes
Social Traits

A trait or factor of an individual that is related to the way they socialize or present themselves to others.


Methadone
Methadose
Metasedin
Dolophine
Symoron
Phenadone
Methex
Physeptone
Pinadone
Phymet
Amidone
Methaddict
Metadol
Methadone Hydrochloride
Biodone

A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)


A selective tyrosine kinase inhibitor for the EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) that is used for the treatment of locally advanced or metastatic NON-SMALL CELL LUNG CANCER.


Lonchocarpus urucu
Derris trifoliata
Derris
Pongamia uliginosa
Derris urucu

A plant genus of the family FABACEAE. The root is a source of rotenoids (ROTENONE) and flavonoids. Some species of Pongamia have been reclassified to this genus and some to MILLETTIA. Some species of Deguelia have been reclassified to this genus.


Summary Report
Research Report
Field Report
Report
Progress Report
Investigative Report
Reports

Detailed account or statement or formal record of the proceedings of a meeting or session. May also document status or progress of an activity or research project.


Sexual Gratification
Orgasm
Sexual Satisfaction

Pleasure derived from sexual experiences.


Dicloxacillin, Monosodium Salt, Mono-Hydrate

Dicloxacillin, Monosodium Salt, Anhydrous

One of the PENICILLINS which is resistant to PENICILLINASE.


Hypocretins Orexin-B Hypocretin-2 Orexins Orexin-A Hypocretin-1

Neuropeptide hormones that play a role in regulating a variety of behavioral and physiological processes in response to motivational stimuli.


Anti-Oxidant Effects
Antioxidants
Anti-Oxidants
Antioxidant Effects
Anti-Oxidant Effect
Antioxidant Effect

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.


A membrane-bound mucin subtype that is primarily found in INTESTINAL MUCOSA. Two closely-related subtypes of this protein have been identified in humans.


Galaxias maculatus
Osmeriformes
Plecoglossus altivelis
Plecoglossidae
Galaxiidae
Smelts
Osmeridae
Plecoglossinae
Galaxiids
Ayu

Species of fish, in the family Osmeridae, found in Japan, Korea, Taiwan, and China.


Chromosomes, Human, 21-22 and Y
Chromosomes, Human, 21 22
Group G Chromosomes
Chromosomes G
Chromosomes, Human, 21-22

The short, acrocentric human chromosomes, called group G in the human chromosome classification. This group consists of chromosome pairs 21 and 22 and the Y chromosome.


LLLT
Laser Phototherapy
Low-Level Light Therapy
Laser Biostimulation
Low-Power Laser Irradiation
Low-Level Laser Therapy
Low-Power Laser Therapy
Laser Irradiation, Low-Power
Laser Therapy, Low-Level
Laser Therapy, Low-Power
Photobiomodulation Therapy

Treatment using irradiation with LASER light of low power intensity so that the effects are not due to heat, as they are in LASER THERAPY.


Monoclonal Gammopathy
Gammopathy, Monoclonal
Paraimmunoglobulinemias
Paraproteinemias
Gammapathy, Monoclonal
Plasma Cell Dyscrasias
Monoclonal Gammapathies
Monoclonal Gammopathies

A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.


Epigenesis, Genetic
Epigenetic Process
Epigenetics Processes
Epigenetic Processes

A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.


A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING.


Stress Test
EuroFit Tests
Exercise Test
Fitness Testing
Eurofit Test Battery
Treadmill Test
Bicycle Ergometry Test
European Fitness Testing Battery
Step Test
Arm Ergometry Test
Physical Fitness Testing
Cardiopulmonary Exercise Test

A set of nine physical fitness tests for flexibility, speed, endurance and strength developed by the Council of Europe for school age children and adults. The tests are performed within 35 to 40 minutes using very simple equipment.


Wolffian Duct
Gartner's Ducts
Gartner Ducts
Wolffian Ducts
Mesonephric Ducts

Remains of atrophied Wolffian ducts in the female, seen as rudimentary tubules in the BROAD LIGAMENT.


FIPV
Coronavirus, Feline Enteric
Feline Enteric Coronavirus
Coronavirus, Feline
FECV
Peritonitis Virus, Infectious Feline
Infectious Peritonitis Virus, Feline
Feline infectious peritonitis virus

A biotype of Feline coronavirus, morphologically indistinguishable from it.


Sulfonphthal
Phenol Red
Sulphental
Sulphonthal
Phenolsulfonphthalein

Red dye, pH indicator, and diagnostic aid for determination of renal function. It is used also for studies of the gastrointestinal and other systems.


Drug Abuse, Intravenous
Substance Abuse, Intravenous
Drug Abuse, Parenteral
Intravenous Drug Abuse

Abuse, overuse, or misuse of a substance by its injection into a vein.


Health Care Costs
Costs, Medical Care
Treatment Costs
Medical Care Costs
Healthcare Costs
Health Costs

The actual costs of providing services related to the delivery of health care, including the costs of procedures, therapies, and medications. It is differentiated from HEALTH EXPENDITURES, which refers to the amount of money paid for the services, and from fees, which refers to the amount charged, regardless of cost.


Spatial Visualization
Spatial Ability
Spatial Navigation

Process by which organisms use various cues to develop a route to a destination and their ability to travel such a planned route.


Synaptic Plasticity
Neurite Pruning
Neuronal Remodeling
Dendritic Remodeling
Neuronal Network Remodeling
Dendritic Arborization
Dendritic Pruning
Neural Plasticity
Neuronal Arborization
Neuronal Plasticity
Neuroplasticity
Plasticity, Neuronal
Dendrite Arborization
Axon Pruning
Neuronal Pruning
Axonal Pruning
Synaptic Pruning
Brain Plasticity
Dendrite Pruning

The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.


Mexiletine
KOE-1173
Novo-Mexiletine
Mexiletene
Mexitil PL
Mexiletine Hydrochloride
KO1173
KO-1173
Mexityl
Mexitil

Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.


Ankle Syndesmosis
Articulatio talocruralis
Ankle Joint
Inferior Tibiofibular Joint
Tibiofibular Ankle Syndesmosis
Distal Tibiofibular Joint
Tibiofibular Syndesmosis
Talocrural Joint

The joint that is formed between the TIBIA and FIBULA held together by ligaments.


Calcium-Calmodulin-Dependent Protein Kinase Type 2 delta Subunit

Calcium-Calmodulin Dependent Protein Kinase II delta

Calcium-Calmodulin-Dependent Protein Kinase Type 2 beta Subunit

Calcium-Calmodulin-Dependent Protein Kinase Type 2 gamma Subunit

Calcium-Calmodulin-Dependent Protein Kinase Type 2 alpha Subunit

Calcium-Calmodulin Dependent Protein Kinase II gamma

Ca(2+)-Calmodulin Dependent Protein Kinase Type II

Calcium-Calmodulin Dependent Protein Kinase II beta

A multifunctional calcium-calmodulin-dependent protein kinase subtype that occurs as an oligomeric protein comprised of twelve subunits. It differs from other enzyme subtypes in that it lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE.


Fluorescence Anisotropy
Anisotropy, Fluorescence
Fluorescence Polarization
Polarization, Fluorescence

Measurement of the polarization of fluorescent light from solutions or microscopic specimens. It is used to provide information concerning molecular size, shape, and conformation, molecular anisotropy, electronic energy transfer, molecular interaction, including dye and coenzyme binding, and the antigen-antibody reaction.


Ethmoid Bone
Cribriform Plate
Horizontal Plate of Ethmoid Bone

A light and spongy (pneumatized) bone that lies between the orbital part of FRONTAL BONE and the anterior of SPHENOID BONE. Ethmoid bone separates the ORBIT from the ETHMOID SINUS. It consists of a horizontal plate, a perpendicular plate, and two lateral labyrinths.


Immunodiagnosis
Diagnosis, Immunologic
Tests, Immunologic
Immunologic Diagnosis
Immunologic Tests
Diagnosis, Immunological
Immunological Tests
Immunologic Test

Immunologic techniques involved in diagnosis.


Fucoxanthin Chlorophyll a-c Binding Proteins

Fucoxanthin Chlorophyll Binding Proteins

A large family of proteins that have been traditionally classified as the light-harvesting proteins of the photosynthetic reaction complex. Chlorophyll binding proteins are also found in non-photosynthetic settings where they may play a photoprotective role in response to light stress.


alpha-1 Chimaerin
alpha-Chimaerin
alpha-2 Chimerin
Chimaerin 1
rhoGAP2 Protein
alpha-1 Chimerin
n-Chimaerin
alpha-Chimerin
alpha-2 Chimaerin
Chimerin 1
alpha1-Chimaerin
arhGAP2 Protein
n-Chimerin

A GTPase activating protein that is specific for RAC GTP-BINDING PROTEINS. It is expressed primarily in the brain and may be involved in signal transduction. The alternatively spliced form of CHIMERIN 1 (alpha-2 Chimerin) contains an additional src homology domain and is expressed in both the brain and testes.


Laburnum anagyroides
Laburnum
Golden Chain
Cytisus laburnum

A plant genus of the family FABACEAE named after the drooping clusters of flowers.


SV40 T Antigens
Polyomaviruses Middle T Proteins
SV40 T Proteins
Polyomavirus T Proteins
Polyomavirus Middle T Antigens
Polyomavirus Small T Antigens
Polyomavirus Transforming Antigens
Polyomavirus Large T Antigens
Polyomavirus Tumor Antigens
Polyomaviruses Large T Proteins
Simian Sarcoma Virus Proteins
Polyomaviruses Small T Proteins
Antigens, Polyomavirus Transforming

Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.


Lymphatic Capillaries
Capillaries, Lymphatic
Venules, Lymphatic
Lymphatic Venules
Lymphatic Vessels

Tubular vessels that are involved in the transport of LYMPH and LYMPHOCYTES.


Ureteroscopic Surgical Procedures
Surgery, Ureteroscopic
Ureteroscopic Surgery
Surgical Procedures, Ureteroscopic
Ureteroscopy

Endoscopic examination, therapy or surgery of the ureter.


Anti-Arrhythmia Drugs
Antiarrhythmia Agents
Antiarrhythmia Drugs
Myocardial Depressants
Anti-Arrhythmia Agents
Anti-Arrhythmics
Antifibrillatory Agents
Antiarrhythmic Drugs
Cardiac Depressants

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.


Decorticate State
Rigidity, Decerebrate
Decorticate Rigidity
Decerebrate Posturing
Decerebrate State
Rigidity, Decorticate

A condition characterized by abnormal posturing of the limbs that is associated with injury to the brainstem. This may occur as a clinical manifestation or induced experimentally in animals. The extensor reflexes are exaggerated leading to rigid extension of the limbs accompanied by hyperreflexia and opisthotonus. This condition is usually caused by lesions which occur in the region of the brainstem that lies between the red nuclei and the vestibular nuclei. In contrast, decorticate rigidity is characterized by flexion of the elbows and wrists with extension of the legs and feet. The causative lesion for this condition is located above the red nuclei and usually consists of diffuse cerebral damage. (From Adams et al., Principles of Neurology, 6th ed, p358)


Sulfosuccinic Acid bis(2-Ethylhexyl) Ester

Dioctyl Sulfosuccinic Acid, Ammonium Salt

Dioctyl Sulfosuccinic Acid, Calcium Salt

Dioctyl Sulfosuccinic Acid, Potassium Salt

Dioctyl Sulfosuccinic Acid, Magnesium Salt

All-purpose surfactant, wetting agent, and solubilizer used in the drug, cosmetics, and food industries. It has also been used in laxatives and as cerumenolytics. It is usually administered as either the calcium, potassium, or sodium salt.


mRNA Isoforms
Messenger RNA Isoforms
RNA Isoforms

The different gene transcripts generated from a single gene by RNA EDITING or ALTERNATIVE SPLICING of RNA PRECURSORS.


Experiential Learning
Active Learning
Problem-Based Learning
Curriculum, Problem-Based
Problem-Based Curricula

Instructional use of examples or cases to teach using problem-solving skills and critical thinking.


Evidence Based Management, Health Care
Evidence Based Health Care Management
Evidence-Based Healthcare
Evidence-Based Health Care
Evidence Based Management, Healthcare
Evidence-Based Practice
Evidence Based Healthcare Management

A way of providing health care that is guided by a thoughtful integration of the best available scientific knowledge with clinical expertise. This approach allows the practitioner to critically assess research data, clinical guidelines, and other information resources in order to correctly identify the clinical problem, apply the most high-quality intervention, and re-evaluate the outcome for future improvement.


Gonabion
Human Chorionic Gonadotropin
Choriogonin
Biogonadil
HCG (Human Chorionic Gonadotropin)
Pregnyl
Chorionic Gonadotropin
Chorulon
Chorionic Gonadotropin, Human
Choriogonadotropin

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).


Vegetable Oils
Oils, Plant
Oils, Vegetable
Plant Oils

Oils derived from plants or plant products.


NK Cell Lectin-Like Receptor Subfamily A, Member 3

NK Cell Lectin-Like Receptor Subfamily A, Member 5

Natural Killer Cell Lectin-Like Receptor Subfamily A

NK Cell Lectin-Like Receptor Subfamily A, Member 6

NK Cell Lectin-Like Receptor Subfamily A, Member 1

NK Cell Lectin-Like Receptor Subfamily A, Member 2

NK Cell Lectin-Like Receptor Subfamily A, Member 8

NK Cell Lectin-Like Receptor Subfamily A, Member 7

NK Cell Lectin-Like Receptor Subfamily A, Member 4

An inhibitory subclass of NK cell lectin-like receptors that interacts with CLASS I MAJOR HISTOCOMPATIBILITY ANTIGENS and prevents the activation of NK CELLS.


rab5 GTP-Binding Protein
rab5A Protein
rab5A GTP-Binding Protein
rab5 GTP-Binding Proteins
rab5 Protein

A genetically related subfamily of RAB GTP-BINDING PROTEINS involved in transport from the cell membrane to early endosomes. This enzyme was formerly listed as EC 3.6.1.47.


Leishmania viannia guyanensis
Leishmania guyanensis guyanensis
Leishmania (Viannia) panamensis
Leishmania viannia panamensis
Leishmania (Viannia) guyanensis
Leishmania guyanensis
Leishmania braziliensis guyanensis
Leishmania brasiliensis guyanensis

A parasitic hemoflagellate of the subgenus Leishmania viannia that infects man and animals and causes mucocutaneous leishmaniasis (LEISHMANIASIS, MUCOCUTANEOUS). Transmission is by Lutzomyia sandflies.


Lipoma, Pleomorphic
Lipoma
Fatty Tumor
Hibernoma
Atypical Lipoma
Lipomatosis, Multiple
Lipomata

A rare benign human tumor consisting of BROWN ADIPOCYTES resembling those found in some hibernating animals.


Factor, Demographic
Demographic Survey
Surveys, Demographic
Demographers
Impact, Demographic
Demographic Factors
Historical Demography
Reverse Survival Method
Stable Population Method
Demographic Analysis
Brass Technique
Analyses, Demographic
Demography, Historical
Brass Technic
Period Analysis
Population Spatial Distribution
Demographic Impacts
Prehistoric Demography
Demographic Accounting
Multiregional Analysis
Demographic and Health Surveys
Factors, Demographic
Analyses, Multiregional
Accounting, Demographic
Impacts, Demographic
Demographic Surveys
Survey, Demographic
Demographic Impact
Demographic Factor
Demographics
Family Reconstitution
Demography
Population Distribution
Analysis, Period
Demography, Prehistoric

Statistical interpretation and description of a population with reference to distribution, composition, or structure.


Nematomorpha Infections
Infections, Nematomorpha
Helminthiasis

Infestation with parasitic worms of the helminth class.


Hyperlipemia, Idiopathic, Burger-Grutz Type

An inherited condition due to a deficiency of either LIPOPROTEIN LIPASE or APOLIPOPROTEIN C-II (a lipase-activating protein). The lack of lipase activities results in inability to remove CHYLOMICRONS and TRIGLYCERIDES from the blood which has a creamy top layer after standing.


Seed Leaf
Cotyledons
Cotyledon
Coleoptiles
Coleoptile
Seed Leaves

A part of the embryo in a seed plant. The number of cotyledons is an important feature in classifying plants. In seeds without an endosperm, they store food which is used in germination. In some plants, they emerge above the soil surface and become the first photosynthetic leaves. (From Concise Dictionary of Biology, 1990)


Hyaluronic Acid
Hyvisc
Luronit
Amo Vitrax
Hyaluronan
Amvisc
Biolon
Healon
Sodium Hyaluronate
Etamucine
Hyaluronate Sodium

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.


Niemann-Pick Disease, Non-Neuronopathic Type

Niemann-Pick Disease, Adult Non-Neuronopathic

An allelic disorder of TYPE A NIEMANN-PICK DISEASE, a late-onset form. It is also caused by mutation in SPHINGOMYELIN PHOSPHODIESTERASE but clinical signs involve only visceral organs (non-neuropathic type).


Familial Amyloid Neuropathy, Portuguese Type

Finnish Type Familial Amyloid Neuropathy

Familial Amyloid Polyneuropathy, Type VI

Familial Portuguese Polyneuritic Amyloidosis

Familial Amyloid Neuropathy, Andrade Type

Portuguese Type Familial Amyloid Neuropathy

Jewish Type Familial Amyloid Polyneuropathy

Appalachian Type Familial Amyloid Polyneuropathy

Familial Amyloid Neuropathy, Finnish Type

Type III Familial Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy, Jewish Type

Familial Amyloid Polyneuropathy, Appalachian Type

Cerebral Amyloid Angiopathy, British Type

Familial Amyloid Polyneuropathy, Type IV

Familial Amyloid Polyneuropathy, Type III

Inherited disorders of the peripheral nervous system associated with the deposition of AMYLOID in nerve tissue. The different clinical types based on symptoms correspond to the presence of a variety of mutations in several different proteins including transthyretin (PREALBUMIN); APOLIPOPROTEIN A-I; and GELSOLIN.


Casein Kinase 2alpha
Protein Kinase CKII
Casein Kinase 2 alpha Subunit
Casein Kinase 2
Casein Kinase 2alpha'
Protein Kinase CK2
Casein Kinase 2 beta Subunit
Casein Kinase II
Casein Kinase-2
Casein Kinase TS
Casein Kinase 2 alpha' Subunit

A ubiquitous casein kinase that is comprised of two distinct catalytic subunits and dimeric regulatory subunit. Casein kinase II has been shown to phosphorylate a large number of substrates, many of which are proteins involved in the regulation of gene expression.


Human Papillomavirus Viruses
HPV, Human Papillomavirus Viruses
Human Papilloma Virus
Papillomaviridae

A large group of viruses that are prevalent in the sexually active population.


Radewerm
Bayluscide
Phenasal
Yomesan
Bayer 2353
Niclosamide, 2-Aminoethanol (1:1)
Bayer 73
Fenasal
Trédémine
Niclosamide
Clonitralide
Niclocide

An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)


Goat Herpesvirus
Caprine Herpesvirus 1
Varicellovirus
Herpesvirus 1, Caprine

Species of VARICELLOVIRUS causing digestive and lethal systemic infections in young goats. Infection in adult goats is mostly subclinical.


Genes, Class I
Genes, MHC Class I
Class I Genes
H-2 Class I Genes
Genes, H-2 Class I
MHC Class I Genes
Genes, HLA Class I
HLA Class I Genes

Genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or complement activity, e.g., B loci (chicken), DLA (dog), GPLA (guinea pig), H-2 (mouse), RT-1 (rat), HLA-A, -B, and -C class I genes of man.


Really Simple Syndication as Topic
Streaming Video as Topic
Webcasts as Topic
RSS as Topic
Podcasts as Topic

Audio or video files that are available for listening or viewing on a local computer or downloadable to a portable media device or MP3 player. Podcasts are usually parts of a series and are distributed via individual episodes.


Unilateral Hyperlucent Lung
Swyer-James Syndrome
Lung, Hyperlucent
Thorax, Hyperlucent
MacLeod Syndrome

A pneumothorax condition marked by complete absence of markings in the chest radiograph.


Palm Pilot
Computers, Handheld
Personal Digital Assistant
Pocket PC
PDA Computer
Computers, Palm-Top
Tablet Computers
Computers, Palmtop

A type of MICROCOMPUTER, sometimes called a personal digital assistant, that is very small and portable and fitting in a hand. They are convenient to use in clinical and other field situations for quick data management. They usually require docking with MICROCOMPUTERS for updates.


Hemocyanin alpha-Haemocyanin alpha-Hemocyanins alpha-Hemocyanin Hemocyanins

Metalloproteins that function as oxygen transport proteins in the HEMOLYMPH of MOLLUSKS and ARTHROPODS. They are characterized by two copper atoms, coordinated with HISTIDINE residues, that reversibly bind a single oxygen molecule; they do not contain HEME groups.