Staphylomycin
Eskalin
Virgimycine
Virginiamycin
Antibiotic 899
Stajac
Founderguard

A cyclic polypeptide antibiotic complex from Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. It consists of 2 major components, VIRGINIAMYCIN FACTOR M1 and virginiamycin Factor S1. It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry.


C3b Inactivator
C3b-C4b Inactivator
C4bC3bINA
Complement 3b-Complement 4b Inactivator
C4b-C3b-INA
Complement C4b-C3b Inactivator
Complement Factor I

A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator.


Locus of Control
Internal-External Control
Sense of Control
External-Internal Control

Personality construct referring to an individual's perception of the locus of events as determined internally by his or her own behavior versus fate, luck, or external forces. (ERIC Thesaurus, 1996).


Motion picture study of successive images appearing on a fluoroscopic screen.


Zinc Finger DNA-Binding Domains
Zinc Finger Motifs
Zinc Fingers

Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.


Coproporphyrinogenase
Coproporphyrinogen III Oxidases
Coproporphyrinogen Oxidase

An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.


Antral Fluid, Ovarian Follicle
Liquor Folliculi
Follicular Fluid

The fluid surrounding the OVUM and GRANULOSA CELLS in the Graafian follicle (OVARIAN FOLLICLE). The follicular fluid contains sex steroids, glycoprotein hormones, plasma proteins, mucopolysaccharides, and enzymes.


Therapeutic use of BACTERIOPHAGES to treat diseases.


Male Sexual Impotence
Erectile Dysfunction
Male Impotence
Impotence

The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction.


An enzyme that catalyzes the reversible oxidation of inosine 5'-phosphate (IMP) to guanosine 5'-phosphate (GMP) in the presence of AMMONIA and NADP+. This enzyme was formerly classified as EC 1.6.6.8.


20 Hydroxysteroid Dehydrogenases
20-Hydroxysteroid Dehydrogenases

A group of enzymes that catalyze the reversible reduction-oxidation reaction of 20-hydroxysteroids, such as from a 20-ketosteroid to a 20-alpha-hydroxysteroid (EC 1.1.1.149) or to a 20-beta-hydroxysteroid (EC 1.1.1.53).


Pathologic Neovascularization
Neovascularization, Pathological
Angiogenesis, Pathological
Pathologic Angiogenesis
Angiogenesis, Pathologic
Neovascularization, Pathologic

A pathologic process consisting of the proliferation of blood vessels in abnormal tissues or in abnormal positions.


Leukocyte- and Platelet-Rich Fibrin
L-PRF
Platelet-Rich Fibrin

A fibrin matrix derived from platelet-rich plasma that contains high concentration of BLOOD PLATELETS; LEUKOCYTES; CYTOKINES; and GROWTH FACTORS. It is used in a variety of clinical and TISSUE ENGINEERING applications.


Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.


A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.


EEE Virus
Eastern Equine Encephalomyelitis Virus
Encephalitis Virus, Eastern Equine
Eastern equine encephalitis virus
Encephalomyelitis Virus, Eastern Equine

A species of ALPHAVIRUS causing encephalomyelitis in Equidae and humans. The virus ranges along the Atlantic seaboard of the United States and Canada and as far south as the Caribbean, Mexico, and parts of Central and South America. Infections in horses show a mortality of up to 90 percent and in humans as high as 80 percent in epidemics.


Threonine-Specific tRNA
tRNA(Thr)
Transfer RNA, Thr
RNA, Transfer, Thr
tRNAThr

A transfer RNA which is specific for carrying threonine to sites on the ribosomes in preparation for protein synthesis.


Designated locations along nerves or organ meridians for inserting acupuncture needles.


Marek Disease
Marek's Disease
Fowl Paralysis

A transmissible viral disease of birds caused by avian herpesvirus 2 (HERPESVIRUS 2, GALLID) and other MARDIVIRUS. There is lymphoid cell infiltration or lymphomatous tumor formation in the peripheral nerves and gonads, but may also involve visceral organs, skin, muscle, and the eye.


Alkaloids, mainly tropanes, elaborated by plants of the family Solanaceae, including Atropa, Hyoscyamus, Mandragora, Nicotiana, Solanum, etc. Some act as cholinergic antagonists; most are very toxic; many are used medicinally.


A pruritic papulovesicular dermatitis occurring as a reaction to many endogenous and exogenous agents (Dorland, 27th ed).


Yin Deficiency
Yin Hsu
Yin Xu
Yinxu
Deficiency, Yin

In the YIN-YANG system of philosophy and medicine, an insufficiency of body fluid (called yinxu), manifesting often as irritability, thirst, constipation, etc. (The Pinyin Chinese-English Dictionary, 1979).


Vascular Endothelial Growth Factor Receptor-1

A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.


Ear Auricle
Pinna, Ear
Ear Auricles
Auricles, Ear
Ear Pinna

The shell-like structure projects like a little wing (pinna) from the side of the head. Ear auricles collect sound from the environment.


Mentha x piperita
Peppermint
Mentha piperita

A plant genus of the family LAMIACEAE that is the source of peppermint oil.


C-36278-Ba
Cephacetrile
Cephacetrile Sodium
Cefacetrile
Celospor

A derivative of 7-aminocephalosporanic acid.


Survival of Motor Neuron 3, Centromeric Protein

Survival of Motor Neuron 2, Centromeric Protein

An SMN complex protein that is closely-related to SURVIVAL OF MOTOR NEURON 1 PROTEIN. In humans, the protein is encoded by an often duplicated gene found near the inversion CENTEROMERE of a large inverted region of CHROMOSOME 5.


Islet Cell Tumor, Malignant
Carcinoma, Islet Cell

A primary malignant neoplasm of the pancreatic ISLET CELLS. Usually it involves the non-INSULIN-producing cell types, the PANCREATIC ALPHA CELLS and the pancreatic delta cells (SOMATOSTATIN-SECRETING CELLS) in GLUCAGONOMA and SOMATOSTATINOMA, respectively.


United States National Library of Medicine

An agency of the NATIONAL INSTITUTES OF HEALTH concerned with overall planning, promoting, and administering programs pertaining to advancement of medical and related sciences. Major activities of this institute include the collection, dissemination, and exchange of information important to the progress of medicine and health, research in medical informatics and support for medical library development.


Factor, Bacterial Sex
F Plasmid
Sex Factor, Bacterial
F Plasmids
Bacterial Sex Factor
Sex Factors, Bacterial
Bacterial Sex Factors
Factors, Bacterial Sex
Sex Factor F
Resistance Transfer Factor
Fertility Factor, Bacterial
F Factor

A plasmid whose presence in the cell, either extrachromosomal or integrated into the BACTERIAL CHROMOSOME, determines the "sex" of the bacterium, host chromosome mobilization, transfer via conjugation (CONJUGATION, GENETIC) of genetic material, and the formation of SEX PILI.


COUMARINS with an amino group, exemplified by NOVOBIOCIN.


Eisenmenger Complex
Eisenmenger's Syndrome
Eisenmenger's Complex
Eisenmenger Syndrome

A condition associated with VENTRICULAR SEPTAL DEFECT and other congenital heart defects that allow the mixing of pulmonary and systemic circulation, increase blood flow into the lung, and subsequent responses to low oxygen in blood. This complex is characterized by progressive PULMONARY HYPERTENSION; HYPERTROPHY of the RIGHT VENTRICLE; CYANOSIS; and ERYTHROCYTOSIS.


Food and Drug Administration Device Approval Process

Process that is gone through in order for a device to receive approval by a government regulatory agency. This includes any required preclinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance. It is not restricted to FDA.


Antrum, Pyloric
Gastric Antrum
Pyloric Antrum

The region between the sharp indentation at the lower third of the STOMACH (incisura angularis) and the junction of the PYLORUS with the DUODENUM. Pyloric antral glands contain mucus-secreting cells and gastrin-secreting endocrine cells (G CELLS).


Rotaxanes Rotaxane Pseudorotaxanes Polyrotaxanes

Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS.


Models, Logistic
Logistic Model
Logistic Models
Logit Models
Logistic Regression

Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.


S cerevisiae Proteins
Baker's Yeast Proteins
Saccharomyces cerevisiae Proteins

Proteins obtained from the species SACCHAROMYCES CEREVISIAE. The function of specific proteins from this organism are the subject of intense scientific interest and have been used to derive basic understanding of the functioning similar proteins in higher eukaryotes.


Chromosome 9 Open Reading Frame 72 Protein

A widely-expressed protein of approximately 400 to 500 amino acids. Its N-terminal region (DENN domain) interacts with RAB GTP-BINDING PROTEINS and may regulate AUTOPHAGY, as well as PROTEIN TRANSPORT to ENDOSOMES. Expansion of the GGGGCC hexanucleotide repeat in the first intron of the C9orf72 gene is associated with FRONTOTEMPORAL DEMENTIA with AMYOTROPHIC LATERAL SCLEROSIS (FTDALS1).


Asbestos, Serpentine, Chrysotile (Mg3(OH)4(Si2O5))

A type of asbestos that occurs in nature as the dihydrate of magnesium silicate. It exists in two forms: antigorite, a plated variety, and chrysotile, a fibrous variety. The latter makes up 95% of all asbestos products. (From Merck Index, 11th ed, p.893)


Cultivated plants or agricultural produce such as grain, vegetables, or fruit. (From American Heritage Dictionary, 1982)


Infections, Bordetella
Bordetella Infections

Infections with bacteria of the genus BORDETELLA.


Lymphoma, AIDS-Associated
HIV-Related Lymphoma
Lymphoma, AIDS-Related
AIDS-Associated Lymphoma
Lymphoma, HIV-Related
AIDS-Related Lymphoma

B-cell lymphoid tumors that occur in association with AIDS. Patients often present with an advanced stage of disease and highly malignant subtypes including BURKITT LYMPHOMA; IMMUNOBLASTIC LARGE-CELL LYMPHOMA; PRIMARY EFFUSION LYMPHOMA; and DIFFUSE, LARGE B-CELL, LYMPHOMA. The tumors are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in AIDS is a complex result of EBV infection, HIV antigenic stimulation, and T-cell-dependent HIV activation.


Bacteria which require oxygen in order to grow and survive.


An order of flightless BIRDS, comprised of one family SPHENISCIDAE.


Any of certain small hoofed mammals of the order Hyracoidea native to Africa and southwestern Asia.


Glycerol Ethers
Alkyl Glyceryl Ethers
Glyceryl Ethers

Compounds in which one or more of the three hydroxyl groups of glycerol are in ethereal linkage with a saturated or unsaturated aliphatic alcohol; one or two of the hydroxyl groups of glycerol may be esterified. These compounds have been found in various animal tissue.


HLA Class I Histocompatibility Antigen, B-18 alpha Chain

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*18 allele family.


Hemagglutination Inhibition Test
Hemagglutination Inhibition Tests

Serologic tests in which a known quantity of antigen is added to the serum prior to the addition of a red cell suspension. Reaction result is expressed as the smallest amount of antigen which causes complete inhibition of hemagglutination.


Plasminogen Activator
Uterine-Tissue Plasminogen Activator
Plasminogen Activators
Extrinsic Plasminogen Activators

A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in the vascular endothelium, particularly in the vessels of the microcirculation.


Institutes and Academies
Institutes
Academies
Academy and Institute
Research Institutes
Academies and Institutes

Organizations representing specialized fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., National Academy of Sciences, Brookings Institution, etc.


Fruit of the Rose known for high quantity of ASCORBIC ACID.


Spindle Assembly Checkpoint
Mitotic Spindle Checkpoints
Mitotic Checkpoints
Spindle Assembly Checkpoint Network
M Phase Cell Cycle Arrest
M Phase Cell Cycle Checkpoint
M Phase Checkpoint
M Phase Cell Cycle Checkpoints

The cellular signaling system that halts the progression of cells through MITOSIS or MEIOSIS if a defect that will affect CHROMOSOME SEGREGATION is detected.


Tumors of the iris characterized by increased pigmentation of melanocytes. Iris nevi are composed of proliferated melanocytes and are associated with neurofibromatosis and malignant melanoma of the choroid and ciliary body. Malignant melanoma of the iris often originates from preexisting nevi.


Doppler Ultrasonography, Pulsed
Ultrasonography, Doppler Pulsed
Doppler Pulsed Ultrasonography
Pulsed Ultrasonography, Doppler
Pulsed Doppler Ultrasonography
Ultrasonography, Doppler, Pulsed
Ultrasonography, Pulsed Doppler

Ultrasonography applying the Doppler effect, with velocity detection combined with range discrimination. Short bursts of ultrasound are transmitted at regular intervals and the echoes are demodulated as they return.


Suction Curettage
Uterine Aspirator
Vacuum Curettage

Aspiration of the contents of the uterus with a vacuum curette.


Dysmyelopoietic Syndromes
Myelodysplastic Syndromes
Hematopoetic Myelodysplasia

Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.


A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.


A group of degraded TRITERPENES which have lost ten carbons (8 from the side chain, C17, and one from C4) so have C20 skeletons which could be misinterpreted as DITERPENES. They especially occur in plants of the SIMAROUBACEAE family.


Endothelial Constitutive Nitric Oxide Synthase

A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in ENDOTHELIAL CELLS.


Infections, Echovirus
Infections, Echo Virus
Echo Virus Infections
Echovirus Infections

Infectious disease processes, including meningitis, diarrhea, and respiratory disorders, caused by echoviruses.


GTPgammaS
Guanosine 5'-(3-O-Thio)Triphosphate
Guanosine 5'-O-(3-Thiotriphosphate)
Guanosine 5'-(gamma-S)Triphosphate
GTP gamma S
gamma-Thio-GTP

Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.


Cytochromes c2
Cytochrome C-2
Ferrocytochrome c2
Cytochrome c2

Type C cytochromes that are small (12-14 kD) single-heme proteins. They function as mobile electron carriers between membrane-bound enzymes in photosynthetic BACTERIA.


FAD
Flavitan
Flavin-Adenine Dinucleotide

A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)


Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.


Liver Specific Transcription Factor LF-B3

A hepatocyte nuclear factor that is closely related to HEPATOCYTE NUCLEAR FACTOR 1-ALPHA but is only weakly expressed in the LIVER. Mutations in hepatocyte nuclear factor 1-beta are associated with renal CYSTS and MATURITY-ONSET DIABETES MELLITUS type 5.


A procedure that modifies REFRACTIVE ERRORS by the transplantation of a donor CORNEA to the anterior surface of the patient's cornea.


Communications networks connecting various hardware devices together within or between buildings by means of a continuous cable or voice data telephone system.


The reduction or regulation of the population of noxious, destructive, or dangerous plants, insects, or other animals.  This includes control of plants that serve as habitats or food sources for animal pests.


Sulfametin Sulfamethoxydiazine Sulfameter Sulfametoxydiazine Sulphamethoxydiazine Sulfamethoxydine Sulfametoxidine Sulfametorinum

Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.


Tachycardia, Reciprocal
Tachycardia, Reciprocating
Reciprocal Tachycardia
Reciprocating Tachycardia

Abnormally rapid heartbeats caused by reentrant conduction over the accessory pathways between the HEART ATRIA and the HEART VENTRICLES. The impulse can also travel in the reverse direction, as in some cases, atrial impulses travel to the ventricles over the accessory pathways and back to the atria over the BUNDLE OF HIS and the ATRIOVENTRICULAR NODE.


A system of therapeutics founded by Samuel Hahnemann (1755-1843), based on the Law of Similars where "like cures like". Diseases are treated by highly diluted substances that cause, in healthy persons, symptoms like those of the disease to be treated.


A family of mammalian membrane glycoproteins characterized by extracellular IMMUNOGLOBULIN DOMAINS. Some members also have an intracellular B30.2-SPRY DOMAIN or SPRY DOMAIN. The butyrophilin protein (BTN) is expressed by MAMMARY GLAND EPITHELIUM during LACTATION; whereas other members are widely expressed in other tissues, including skeletal muscle, intestine, ERYTHROID CELLS (ERMAP protein); and nerve tissue (MYELIN-OLIGODENDROCYTE GLYCOPROTEIN).


Toxins produced, especially by bacterial or fungal cells, and released into the culture medium or environment.


Patient's regular engagement with medical care after initial entry into the system.


Post-Concussion Syndrome
Post-Concussive Symptoms
Post-Concussive Syndrome
Post-Concussion Symptoms
Post-Concussive Syndrome, Chronic

The organic and psychogenic disturbances observed after closed head injuries (HEAD INJURIES, CLOSED). Post-concussion syndrome includes subjective physical complaints (i.e. headache, dizziness), cognitive, emotional, and behavioral changes. These disturbances can be chronic, permanent, or late emerging.


Typhus, Murine
Rickettsia typhi Infection
Murine Typhus
Murine Typhus Infection
Endemic Typhus
Typhus, Endemic Flea-Borne

An infectious disease clinically similar to epidemic louse-borne typhus (TYPHUS, EPIDEMIC LOUSE-BORNE), but caused by RICKETTSIA TYPHI, which is transmitted from rat to man by the rat flea, XENOPSYLLA CHEOPIS.


Chronic Daily Headache
Headache, Intractable
Chronic Headache
Cephalgia Syndromes
Headache Disorders
Headache Syndromes

Various conditions with the symptom of HEADACHE. Headache disorders are classified into major groups, such as PRIMARY HEADACHE DISORDERS (based on characteristics of their headache symptoms) and SECONDARY HEADACHE DISORDERS (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)


Amlodipine - Valsartan
Amlodipine-Valsartan Drug Combination
Amlodipine-Valsartan
Exforge
Amlodipine, Valsartan Drug Combination

A pharmaceutical preparation of amlodipine and valsartan that is used for the treatment of HYPERTENSION.


CABP-P14
60B8-A Antigen
S100A9 Protein
Macrophage-Related Protein-14
Leukocyte L1 Protein Heavy Chain
MRP-14 Protein
Calgranulin B
Myeloid Calcium-Binding Protein p14
MRP14 Protein
Antigen 60B8-A

A 13.2-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN A and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin B is expressed at high concentrations in GRANULOCYTES during early monocyte differentiation, and serum calgranulin B levels are elevated in many inflammatory disorders such as CYSTIC FIBROSIS.


Wearable Devices
Wearable Technology
Electronic Skin
Wearable Electronic Devices

Electronic implements worn on  the body as an implant or as an accessory. Examples include wearable diagnostic devices, wearable ACTIVITY TRACKERS, wearable INFUSION PUMPS, wearable computing devices, SENSORY AIDS, and electronic pest repellents.


Space Adaptation Syndrome
Space Motion Sickness

Disorder characterized by nausea, vomiting, and dizziness, possibly in response to vestibular disorientation or fluid shifts associated with space flight. (From Webster's New World Dictionary)


Von Hippel-Lindau Tumor Suppressor Protein

A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME.


Serpins
Serpin Protease Inhibitors
Serpin Superfamily
Serpin Peptidase Inhibitors

A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.


Gifts, Financial
Gift Giving
Gifts
Giftgiving
Financial Contributions

The bestowing of tangible or intangible benefits, voluntarily and usually without expectation of anything in return. However, gift giving may be motivated by feelings of ALTRUISM or gratitude, by a sense of obligation, or by the hope of receiving something in return.


Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.


Herpes Simplex Virus Vaccines
Simplexvirus Vaccines
HSV Vaccines

Vaccines or candidate vaccines used to prevent infection with viruses from the genus SIMPLEXVIRUS. This includes vaccines for HSV-1 and HSV-2.


Muscle Tenderness
Muscle Soreness
Muscle Pain
Myalgia

Painful sensation felt when pressure is applied to the muscles.


Mental Health Nursing
Psychosocial Nursing
Psychiatric Nursing
Nursing, Psychiatric

A nursing specialty concerned with both the psychological and social aspects of a patient's life, and how social conditions relate to mental and emotional health.


Salvia miltiorrhizae
Dan-Shen
Salvia miltiorrhiza
Tan Seng
Danshen
Chinese Salvia

A plant species which is known as an Oriental traditional medicinal plant.


The space between the inner and outer membranes of a cell that is shared with the cell wall.


Brown Adipocytes
Brown Fat Cells
Adipocytes, Brown

Fat cells with dark coloration due to the densely packed MITOCHONDRIA. They contain numerous small lipid droplets or vacuoles. Their stored lipids can be converted directly to energy as heat by the mitochondria.


Neurons whose primary neurotransmitter is DOPAMINE.


Poly ADP-Ribose Synthase
Poly ADP Ribose Transferase
Poly(ADPribose) Polymerase
Poly(ADPR) Polymerase
ADP-Ribosyltransferase (Polymerizing)
Poly ADP Ribose Polymerase
Poly(ADP-ribose) Polymerase
Poly(ADP-ribose) Polymerases
Poly(ADP-Ribose) Transferase
Poly(ADP-Ribose) Synthase
PARP Polymerase

Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.


Bibliography, Statistical
Bibliographies, Statistical
Statistical Bibliographies
Bibliometric Analysis
Bibliometrics
Statistical Bibliography
Analysis, Bibliometric

The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)


CD138 Antigens
Syndecan 1
Antigens, CD138
Syndecan-1
CD138 Antigen

A syndecan that interacts with EXTRACELLULAR MATRIX PROTEINS and plays a role CELL PROLIFERATION and CELL MIGRATION.


Fourth Cranial Nerve Injuries
Injury, Fourth Cranial Nerve
Trochlear Nerve Trauma
Trochlear Nerve Transection
Fourth Cranial Nerve Injury
Cranial Nerve IV Injury
Trochlear Neuropathy, Traumatic
Trochlear Nerve Injuries
Trochlear Nerve Avulsion
Fourth-Nerve Palsy, Traumatic
Injury, Cranial Nerve IV
Fourth-Nerve Trauma
Traumatic Fourth-Nerve Palsy
Trochlear Nerve Contusion

Traumatic injuries to the TROCHLEAR NERVE.


Volcanic Ash
Volcanic Gases
Volcanic Eruption
Volcanic Eruptions

The ash, dust, gases, and lava released by volcanic explosion. The gases are volatile matter composed principally of about 90% water vapor, and carbon dioxide, sulfur dioxide, hydrogen, carbon monoxide, and nitrogen. The ash or dust is pyroclastic ejecta and lava is molten extrusive material consisting mainly of magnesium silicate. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)


A subclass of monoterpenes that contain a single benzene ring structure with an isopropyl group and one or more methyl groups.


Antibodies from an individual that react with ISOANTIGENS of another individual of the same species.


11 beta-Hydroxysteroid Dehydrogenase Type 2

11beta-Hydroxysteroid Dehydrogenase Type 2

11-beta-Hydroxysteroid Dehydrogenase Type 2

An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to catalyze the dehydrogenation of CORTISOL to CORTISONE. It is found predominantly in mineralocorticoid target tissues such as the KIDNEY; COLON; SWEAT GLANDS; and the PLACENTA. Absence of the enzyme leads to a fatal form of childhood hypertension termed, APPARENT MINERALOCORTICOID EXCESS SYNDROME.


2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.


Dihydroxyacetone Vitadye Chromelin 1,3-Dihydroxy-2-Propanone

A ketotriose compound. Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage. It is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent.


A genus of elapid snake indigenous to Southern Africa. It is closely related to the cobras (Naja) and is capable of spitting its venom.


Fukushima Nuclear Accident, Japan
Fukushima Nuclear Accident
Fukushima Nuclear Disaster

Nuclear power accident that occurred following the Tohoku-Kanto earthquake of March 11, 2011 in the northern region of Japan.


Thymoxamine
Carlytène
Icavex
Moxisylyte
Moxisylyte Hydrochloride
Thymoxyalcylamine
Acetoxythymoxamine

An alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312)


Specificity Protein 1 Transcription Factor

Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.


Achylia Gastrica
Hypochlorhydria
Achlorhydria

A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion.


Persons who do not smoke but that have a history of SMOKING.


A plant genus of the family LAMIACEAE that contains leonurine.


Hospital Ancillary Services
Ancillary Services, Hospital
Services, Hospital Ancillary

Those support services other than room, board, and medical and nursing services that are provided to hospital patients in the course of care. They include such services as laboratory, radiology, pharmacy, and physical therapy services.


Therapy, Ultraviolet
Actinotherapy
Ultraviolet Therapy

The use of ultraviolet electromagnetic radiation in the treatment of disease, usually of the skin. This is the part of the sun's spectrum that causes sunburn and tanning. Ultraviolet A, used in PUVA, is closer to visible light and less damaging than Ultraviolet B, which is ionizing.


A group of compounds that are derivatives of oxo-pyrrolidines. A member of this group is 2-oxo pyrrolidine, which is an intermediate in the manufacture of polyvinylpyrrolidone. (From Merck Index, 11th ed)


Lactogenic Hormone, Pituitary
PRL (Prolactin)
Mammotropic Hormone, Pituitary
Prolactin
Mammotropin

A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.


Lac Repressors
LacI Proteins
Lac Repressor

Bacterial repressor proteins that bind to the LAC OPERON and thereby prevent the synthesis of proteins involved in catabolism of LACTOSE. When lactose levels are high lac repressors undergo an allosteric change that causes their release from the DNA and the resumption of lac operon transcription.


A single, unpaired primary lymphoid organ situated in the MEDIASTINUM, extending superiorly into the neck to the lower edge of the THYROID GLAND and inferiorly to the fourth costal cartilage. It is necessary for normal development of immunologic function early in life. By puberty, it begins to involute and much of the tissue is replaced by fat.


American Indians
Indians, North American
Amerinds, North American
Native Americans

Individual members of North American ethnic groups with ancient historic ancestral origins in Asia.


A whiplike motility appendage present on the surface cells. Prokaryote flagella are composed of a protein called FLAGELLIN. Bacteria can have a single flagellum, a tuft at one pole, or multiple flagella covering the entire surface. In eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella have the same basic structure as CILIA but are longer in proportion to the cell bearing them and present in much smaller numbers. (From King & Stansfield, A Dictionary of Genetics, 4th ed)


A cytokine produced by activated T-LYMPHOCYTES that stimulates the migration of CD4-POSITIVE LYMPHOCYTES and monocytes. It has been reported to suppress HIV replication.


Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.


Urea Cycle Disorders
Urea Cycle Disorders, Inborn
Inborn Urea Cycle Disorder

Rare congenital metabolism disorders of the urea cycle. The disorders are due to mutations that result in complete (neonatal onset) or partial (childhood or adult onset) inactivity of an enzyme, involved in the urea cycle. Neonatal onset results in clinical features that include irritability, vomiting, lethargy, seizures, NEONATAL HYPOTONIA; RESPIRATORY ALKALOSIS; HYPERAMMONEMIA; coma, and death. Survivors of the neonatal onset and childhood/adult onset disorders share common risks for ENCEPHALOPATHIES, METABOLIC, INBORN; and RESPIRATORY ALKALOSIS due to HYPERAMMONEMIA.


An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.


T-Cell Epitope
T-Lymphocyte Epitope
T-Lymphocyte Epitopes
Epitopes, T-Lymphocyte
T-Cell Epitopes

Antigenic determinants recognized and bound by the T-cell receptor. Epitopes recognized by the T-cell receptor are often located in the inner, unexposed side of the antigen, and become accessible to the T-cell receptors after proteolytic processing of the antigen.


Computational Neural Networks
Perceptrons
Neural Network Models
Connectionist Models
Neural Networks, Computer
Neural Networks (Computer)
Models, Neural Network

A computer architecture, implementable in either hardware or software, modeled after biological neural networks. Like the biological system in which the processing capability is a result of the interconnection strengths between arrays of nonlinear processing nodes, computerized neural networks, often called perceptrons or multilayer connectionist models, consist of neuron-like units. A homogeneous group of units makes up a layer. These networks are good at pattern recognition. They are adaptive, performing tasks by example, and thus are better for decision-making than are linear learning machines or cluster analysis. They do not require explicit programming.


Ubiquitin-Protein Ligases
E3 Ligase
Ubiquitin Ligase E3
Ubiquitin-Protein Ligase
Ubiquitin-Protein Ligase E3
E3 Ubiquitin Ligase

A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.


Modification Methylases (Adenine Specific)

DNA Modification Methylases Adenine Specific

Site Specific Methyltransferases (Adenine Specific)

DNA Modification Methylases (Adenine-Specific)

An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.


T-Cell Receptor gamma Genes
T-Cell Receptor gamma-Chain Genes
Genes, T-Cell Receptor gamma
TcR gamma Genes

DNA sequences encoding the gamma chain of the T-cell receptor. The human gamma-chain locus is organized similarly to the TcR beta-chain locus.


Myrtle, Bog
Sweet Gale
Bayberry
Myrica
Bog Myrtle

A plant genus of the family MYRICACEAE. Members contain myricanol. The common name of bayberry is similar to the name barberry which is used for BERBERIS and MAHONIA.


Maximally Tolerated Dose
Maximum Tolerated Dose
Maximal Tolerated Dose

The highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than carcinogenicity. (from Lewis Dictionary of Toxicology, 1st ed)


Blood in the SEMEN, usually due to INFLAMMATION of the PROSTATE, the SEMINAL VESICLES, or both.


Pulmonary Alveoli
Pulmonary Alveolus
Alveoli, Pulmonary
Alveolus, Pulmonary

Small polyhedral outpouchings along the walls of the alveolar sacs, alveolar ducts and terminal bronchioles through the walls of which gas exchange between alveolar air and pulmonary capillary blood takes place.


Phototrophic Process
Phototrophic Processes
Phototrophic Growth
Phototrophy

Processes by which phototrophic organisms use sunlight as their primary energy source. Contrasts with chemotrophic processes which do not depend on light and function in deriving energy from exogenous chemical sources. Photoautotrophy (or photolithotrophy) is the ability to use sunlight as energy to fix inorganic nutrients to be used for other organic requirements. Photoautotrophs include all GREEN PLANTS; GREEN ALGAE; CYANOBACTERIA; and green and PURPLE SULFUR BACTERIA. Photoheterotrophs or photoorganotrophs require a supply of organic nutrients for their organic requirements but use sunlight as their primary energy source; examples include certain PURPLE NONSULFUR BACTERIA. Depending on environmental conditions some organisms can switch between different nutritional modes (AUTOTROPHY; HETEROTROPHY; chemotrophy; or phototrophy) to utilize different sources to meet their nutrients and energy requirements.


Transplantation, Isogeneic
Syngeneic Transplantation
Transplantation, Syngeneic
Isografting
Isogeneic Transplantation
Isograft Transplantation

Transplantation between genetically identical individuals, i.e., members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains.


Ferroxidase I
Ceruloplasmin Ferroxidase
Ceruloplasmin Oxidase
Ceruloplasmin
alpha(2)-Ceruloplasmin
Caeruloplasmin
Ferroxidase

A multi-copper blood FERROXIDASE involved in iron and copper homeostasis and inflammation.


Trypanosomiasis, South American
American Trypanosomiasis
Trypanosoma cruzi Infection
Chagas Disease
Chagas' Disease

Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.


Receptor, Interleukin-18
IL-18 Receptor
IL-18 Receptors
Interleukin-18 Receptor
Interleukin-18 Receptors
Interleukin 18 Receptors
Receptors, Interleukin-18

Cell surface receptors for INTERLEUKIN-18 found on a variety of cell types including MACROPHAGES; NEUTROPHILS; NK CELLS; ENDOTHELIAL CELLS; and SMOOTH MUSCLE CELLS. They are formed as a heterodimer of alpha and beta subunits.


Pulp, Dental
Pulps, Dental
Dental Pulp
Dental Pulps

A richly vascularized and innervated connective tissue of mesodermal origin, contained in the central cavity of a tooth and delimited by the dentin, and having formative, nutritive, sensory, and protective functions. (Jablonski, Dictionary of Dentistry, 1992)


Bladder Stones
Vesical Calculi
Calculi of Urinary Bladder
Cystoliths
Bladder Calculi
Urinary Bladder Stones
Urinary Bladder Calculi

Stones in the URINARY BLADDER; also known as vesical calculi, bladder stones, or cystoliths.


Burns caused by contact with or exposure to CAUSTICS or strong ACIDS.


Infant, Very Low Birth Weight
Very Low Birth Weight
Very-Low-Birth-Weight Infant

An infant whose weight at birth is less than 1500 grams (3.3 lbs), regardless of gestational age.


Angina Pectoris with Normal Coronary Arteriogram

ANGINA PECTORIS or angina-like chest pain with a normal coronary arteriogram and positive EXERCISE TEST. The cause of the syndrome is unknown. While its recognition is of clinical importance, its prognosis is excellent. (Braunwald, Heart Disease, 4th ed, p1346; Jablonski Dictionary of Syndromes & Eponymic Diseases, 2d ed). It is different from METABOLIC SYNDROME X, a syndrome characterized by INSULIN RESISTANCE and HYPERINSULINEMIA, that has increased risk for cardiovascular disease.


Choline Acetylase
Choline Acetyltransferase
Choline O-Acetyltransferase

An enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline. EC 2.3.1.6.


Self Administration
Administration, Self

Administration of a drug or chemical by the individual under the direction of a physician. It includes administration clinically or experimentally, by human or animal.


Melanocyte-Stimulating Hormones
Melanophore-Stimulating Hormone
MSH (Melanocyte-Stimulating Hormones)
MSH
Melanotropin

Peptides with the ability to stimulate pigmented cells MELANOCYTES in mammals and MELANOPHORES in lower vertebrates. By stimulating the synthesis and distribution of MELANIN in these pigmented cells, they increase coloration of skin and other tissue. MSHs, derived from pro-opiomelanocortin (POMC), are produced by MELANOTROPHS in the INTERMEDIATE LOBE OF PITUITARY; CORTICOTROPHS in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic neurons in the ARCUATE NUCLEUS OF HYPOTHALAMUS.


Pax Transcription Factors
Paired Box Transcription Factors

A family of transcription factors that control EMBRYONIC DEVELOPMENT within a variety of cell lineages. They are characterized by a highly conserved paired DNA-binding domain that was first identified in DROSOPHILA segmentation genes.


Ureaplasma urealyticum
Ureaplasma urealyticum biovar 2

A species of gram-negative bacteria found in the human genitourinary tract (UROGENITAL SYSTEM), oropharynx, and anal canal. Serovars 1, 3, 6, and 14 have been reclassed into a separate species UREAPLASMA parvum.


NADH (Acceptor) Oxidoreductase
NADH Dehydrogenase
Diaphorase (NADH Dehydrogenase)
NADH Cytochrome c Oxidoreductase
NADH Cytochrome c Reductase

A flavoprotein and iron sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. In eukaryotes the enzyme can be found as a component of mitochondrial electron transport complex I. Under experimental conditions the enzyme can use CYTOCHROME C GROUP as the reducing cofactor. The enzyme was formerly listed as EC 1.6.2.1.


Retinal Arterial Macroaneurysm
Retinal Macroaneurysm
Retinal Arteriolar Macroaneurysm
Ruptured Retinal Arterial Macroaneurysm

An acquired dilation of the retinal artery often associated with systemic HYPERTENSION.


erbB-3 Genes
c-erbB-3 Genes
Genes, erbB
erbB Genes

Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to, the avian erythroblastosis virus (AEV). These genes code for the epidermal growth factor receptor (EGFR) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1 (GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities of expression in various human neoplasms.


Leishmania leishmania mexicana
Leishmania mexicana amazonensis
Leishmania (Leishmania) mexicana
Leishmania mexicana
Leishmania mexicana mexicana

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals including rodents. The Leishmania mexicana complex causes both cutaneous (LEISHMANIASIS, CUTANEOUS) and diffuse cutaneous leishmaniasis (LEISHMANIASIS, DIFFUSE CUTANEOUS) and includes the subspecies amazonensis, garnhami, mexicana, pifanoi, and venezuelensis. L. m. mexicana causes chiclero ulcer, a form of cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) in the New World. The sandfly, Lutzomyia, appears to be the vector.


Papilloma Virus DNA Probes
Human Papilloma Virus DNA Probes
HPV DNA Probes
DNA Probes, HPV

DNA probes specific for the identification of human papilloma virus.


A pyrrolidine-carbonitrile derivative and potent inhibitor of DIPEPTIDYL PEPTIDASE 4 that is used in the treatment of TYPE 2 DIABETES MELLITUS.


Cholecystectomy, Celioscopic
Laparoscopic Cholecystectomy
Cholecystectomy, Laparoscopic

Excision of the gallbladder through an abdominal incision using a laparoscope.


A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS. It regulates BONE MORPHOGENETIC PROTEIN signaling and is essential for PHYSIOLOGICAL ANGIOGENESIS.


Intrinsically Disordered Proteins
Unstructured Proteins
Natively Unfolded Proteins

Functional proteins that do not have unique, stable, folded, three-dimensional native structures or that possess non-ordered regions under physiological conditions. They are characterized by extraordinary structural flexibility and plasticity, which enable them to adopt different conformations in response to different stimuli or different interactions.


sigma Receptor
Receptors, Opioid, sigma
Opioid Receptors, sigma
sigma Receptors
Receptors, sigma Opioid
Receptors, sigma

A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues.


The family Geomyidae of burrowing rodents, commonly called pocket gophers. There are six genera, all found in North America.


First lymph node to receive drainage from the primary tumor. SENTINEL LYMPH NODE BIOPSY is performed to determine early METASTASIS status because cancer cells may appear first in the sentinel node.


Propanedial
Malonaldehyde
Malonyldialdehyde
Malonylaldehyde
Malondialdehyde
Sodium Malondialdehyde


Bottlenosed Dolphin
Bottle-Nosed Dolphin
Tursiops truncatus
Bottlenose Dolphins
Bottle-Nose Dolphins
Bottle-Nosed Dolphins

The species Tursiops truncatus, in the family Delphinidae, characterized by a bottle-shaped beak and slightly hooked broad dorsal fin.


Accident Injury
Accidental Injuries
Accidental Injury

Injuries resulting from events or circumstances that are unforeseen, unplanned, unanticipated, and without premeditation.


Sexual behavior that prevents or reduces the spread of SEXUALLY TRANSMITTED DISEASES or PREGNANCY.


Health clinics offering fertility treatment services.


Anti-Sense RNA
Antisense RNA
RNA, Antisense

RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes.


A signal transducing adaptor protein and tumor suppressor protein. It forms a complex with activated RECEPTOR-REGULATED SMAD PROTEINS. The complex then translocates to the CELL NUCLEUS and regulates GENETIC TRANSCRIPTION of target GENES.


A genus, Muntiacus, of the deer family (Cervidae) comprising six species living in China, Tibet, Nepal, India, the Malay Peninsula, and neighboring island countries. They are usually found in forests and areas of dense vegetation, usually not far from water. They emit a deep barklike sound which gives them the name "barking deer." If they sense a predator they will "bark" for an hour or more. They are hunted for their meat and skins; they thrive in captivity and are found in many zoos. The Indian muntjac is believed to have the lowest chromosome number in mammals and cell lines derived from them figure widely in chromosome and DNA studies. (From Walker's Mammals of the World, 5th ed., p1366)


RNA Polymerase II, Transcription Factor A

An RNA POLYMERASE II specific transcription factor. It may play a role in transcriptional activation of gene expression by interacting with the TATA-BOX BINDING PROTEIN component of TRANSCRIPTION FACTOR TFIID.


CBA Studies
Controlled Before-After Studies
Controlled Before and After Studies

A study in which observations are made before and after an intervention, both in a group that receives the intervention and in a control group that does not.


Diseases, Occupational
Occupational Illnesses
Occupational Diseases

Diseases caused by factors involved in one's employment.


HSP27 Protein
Heat-Shock Protein 27
Heat-Shock Proteins 27
HSP27 Proteins
HSP27 Heat-Shock Proteins
Heat Shock Protein beta-1

A subfamily of small heat-shock proteins that function as molecular chaperones that aid in refolding of non-native proteins. They play a protective role that increases cellular survival during times of stress.


Lutembacher Syndrome
Lutembacher's Syndrome

A condition characterized by a combination of OSTIUM SECUNDUM ATRIAL SEPTAL DEFECT and an acquired MITRAL VALVE STENOSIS.


CHAMPUS
Health Benefit Plans, Employee
Employee Health Benefit Plans

Health insurance plans for employees, and generally including their dependents, usually on a cost-sharing basis with the employer paying a percentage of the premium.


CENPA Protein
Centromere Protein A
Centromere Protein 17K
CENP-A Protein
Centromere Autoantigens 17K

A 17 kDa, centromeric, poly(ADP)-ribose binding protein that is structurally similar to HISTONE H3 and localizes to NUCLEOSOMES within the CENTROMERE; specifically within the region that binds KINETOCHORES, where it replaces histone H3. It plays a critical role in recruiting kinetochore proteins and progression through MITOSIS, chromosome segregation, and CYTOKINESIS. It also binds sera from patients with some scleroderma-like AUTOIMMUNE DISEASES.


Angel Dust Abuse
PCP Abuse
Phencyclidine Abuse
Phencyclidine-Related Disorders

The misuse of phencyclidine with associated psychological symptoms and impairment in social or occupational functioning.


Complex Single Ventricle
Univentricular Heart

Rare congenital heart malformation with a single ventricle (HEART VENTRICLES) instead of the usual two.


Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.


Angioneurotic Edema, Hereditary, with Normal C1 Inhibitor Concentration and Function

HAE with Normal C1 Inhibitor Concentration and Function

Hereditary Angioedema with Normal C1 Inhibitor Activity

A form of hereditary angioedema that occurs in women and is precipitated or worsened by high ESTROGEN levels. It is associated with mutations in the gene for FACTOR XII that result in its increased activity.


Poly-glutathione peptides composed of (Glu-Cys)n-Gly where n is two to seven. They are biosynthesized by glutathione gamma-glutamylcysteinyltransferase and are found in many PLANTS; YEASTS; and algae. They sequester HEAVY METALS.


Polymethyl Methacrylate, Surgical Simplex P

Polymethyl Methacrylate, Surgical Simplex Bone Cement, Ammonium Salt

Polymerized methyl methacrylate monomers which are used as sheets, moulding, extrusion powders, surface coating resins, emulsion polymers, fibers, inks, and films (From International Labor Organization, 1983). This material is also used in tooth implants, bone cements, and hard corneal contact lenses.


Abnormalities, Mouth
Mouth Abnormalities

Congenital absence of or defects in structures of the mouth.


Autosomal Recessive Anhidrotic Ectodermal Dysplasia

Anhidrotic Ectodermal Dysplasia, Autosomal Recessive

Anhidridic Ectodermal Dysplasia, Autosomal Recessive

Ectodermal Dysplasia, Anhidrotic, Autosomal Recessive

Autosomal Recessive Anhydrotic Ectodermal Dysplasia

Ectodermal Dysplasia, Hypohydrotic, Autosomal Recessive

Anhydridic Ectodermal Dysplasia, Autosomal Recessive

Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive

An autosomal recessive form of ectodermal dysplasia which is due to mutations in the gene for the EDAR RECEPTOR or EDAR-ASSOCIATED DEATH DOMAIN PROTEIN.


A species in the genus PARVOVIRUS that has the ability to replicate and kill tumor cells in culture.


Spina Bifida, Open
Spina Bifida Cystica
Spina Bifida Aperta
Spina Bifida Manifesta

A form of spinal dysraphism associated with a protruding cyst made up of either meninges (i.e., a MENINGOCELE) or meninges in combination with spinal cord tissue (i.e., a MENINGOMYELOCELE). These lesions are frequently associated with spinal cord dysfunction, HYDROCEPHALUS, and SYRINGOMYELIA. (From Davis et al., Textbook of Neuropathology, 2nd ed, pp224-5)


Diacetyldapsone Acedapsone Sulfadiamine DADDS Acetyldiphenazonum Hansolar Rodilone 4',4'''-Sulfonylbis(acetanilide) 4,4'-Diacetyldiaminodiphenylsulfone

Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent.


ATP Binding Cassette Transporter, Sub-Family G, Member 2

ATP Binding Cassette Transporter, Subfamily G, Member 2

ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.


A natural tocopherol with less antioxidant activity than alpha-tocopherol. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. As in GAMMA-TOCOPHEROL, it also has three methyl groups on the 6-chromanol nucleus but at different sites.


Discoidin Domain Receptors
DDR Proteins
Discoidin Domain Receptor

Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.


Post-Synaptic Density
Postsynaptic Density Region
Postsynaptic Density
Post-Synaptic Density Region

Cytoskeleton specialization at the cytoplasmic side of postsynaptic membrane in SYNAPSES. It is involved in neuronal signaling and NEURONAL PLASTICITY and comprised of GLUTAMATE RECEPTORS; scaffolding molecules (e.g., PSD95, PSD93), and other proteins (e.g., CaCMKII).


An enzyme of the urea cycle which splits argininosuccinate to fumarate plus arginine. Its absence leads to the metabolic disease ARGININOSUCCINIC ACIDURIA in man. EC 4.3.2.1.


Tracheoesophageal Fistula
Esophagotracheal Fistula

Abnormal passage between the ESOPHAGUS and the TRACHEA, acquired or congenital, often associated with ESOPHAGEAL ATRESIA.


Glycolaldehyde Dehydrogenase
Glycol Aldehyde Dehydrogenase

An enzyme that catalyzes the oxidation of glycolaldehyde to glycolate, using NAD and NADP as COENZYMES.


Preeclampsia Eclampsia 1
Pregnancy Toxemias
Hypertension-Edema-Proteinuria Gestosis
Toxemias, Pregnancy
Proteinuria-Edema-Hypertension Gestosis
Gestosis, EPH
Preeclampsia
Toxemia Of Pregnancy
Edema-Proteinuria-Hypertension Gestosis
Pre-Eclampsia
EPH Complex
EPH Toxemias
EPH Gestosis

A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.


The valve between the left atrium and left ventricle of the heart.


Narrowing of the caliber of the BRONCHI, physiologically or as a result of pharmacological intervention.


2,4,6-Triethylimino-1,3,5-Triazine
Tretamine
Triethylene Melamine
Triethylenemelamine

Toxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.


Substances used to clean dentures; they are usually alkaline peroxides or hypochlorites, may contain enzymes and release oxygen. Use also for sonic action cleaners.


C-Type Lectin
Receptors, C-Type Lectin
C-Type Lectins
Lectins, C-Type
Lectin, C-Type

A class of animal lectins that bind to carbohydrate in a calcium-dependent manner. They share a common carbohydrate-binding domain that is structurally distinct from other classes of lectins.


Colonic Diseases, Functional
Functional Colonic Diseases

Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.


Ornid
Bretylium Tosilate
Bretylium Tosylate
Bretylate
Bretylol

An agent that blocks the release of adrenergic transmitters and may have other actions. It was formerly used as an antihypertensive agent, but is now proposed as an anti-arrhythmic.


Class I Phosphatidylinositol 3-Kinases
Class I Phosphatidylinositol 3-Kinase
Phosphatidylinositol 3-Kinase, Class I

A phosphatidylinositol 3-kinase subclass that includes enzymes with a specificity for 1-phosphatidylinositol, 1-phosphatidylinositol 4-phosphate, and 1-phosphatidylinositol 4,5-bisphosphate. Members of this enzyme subclass are activated by cell surface receptors and occur as heterodimers of enzymatic and regulatory subunits.


Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.


Melanocortin Receptor
Receptor, Melanocortin
Melanocortin Receptors
Receptors, Melanocortin

A family of G-protein-coupled receptors that have specificity for MELANOCYTE-STIMULATING HORMONES and ADRENOCORTICOTROPIC HORMONE. There are several subtypes of melanocortin receptors, each having a distinct ligand specificity profile and tissue localization.


Slime Molds, Plasmodial
Myxomycota
Protosteliomycetes
Myxomycetes
Slime Molds, True

A division of organisms that exist vegetatively as complex mobile plasmodia, reproduce by means of spores, and have complex life cycles. They are now classed as protozoa but formerly were considered fungi.


myb Proto-Oncogene Proteins
Proto-Oncogene Protein myb
Proto-Oncogene Products c-myb
c-myb Proteins
Proto-Oncogene Proteins myb
Proto-Oncogene Proteins c-myb
c-myb Protein

Cellular DNA-binding proteins encoded by the myb gene (GENES, MYB). They are expressed in a wide variety of cells including thymocytes and lymphocytes, and regulate cell differentiation. Overexpression of myb is associated with autoimmune diseases and malignancies.


Chorismate Mutase
Chorismate Pyruvatemutase

An isomerase that catalyzes the conversion of chorismic acid to prephenic acid. EC 5.4.99.5.


Minichromosome Maintenance Complex Component 7

A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6.


A prepared mixture of cooked and/or raw vegetables, FRUIT, or other foods, garnished with a dressing CONDIMENT, and eaten as a MEAL or side dish.


Bulbar Polio
Poliomyelitis, Medullary Involvement
Bulbar Poliomyelitis
Poliomyelitis, Bulbar

A form of paralytic poliomyelitis affecting neurons of the MEDULLA OBLONGATA of the brain stem. Clinical features include impaired respiration, HYPERTENSION, alterations of vasomotor control, and dysphagia. Weakness and atrophy of the limbs and trunk due to spinal cord involvement is usually associated. (From Adams et al., Principles of Neurology, 6th ed, p765)


The superior part of the upper extremity between the SHOULDER and the ELBOW.


A plant genus of the family MORACEAE. It is the source of the familiar fig fruit and the latex from this tree contains FICAIN.


Wautersia eutropha
Alcaligenes eutropha
Ralstonia eutropha
Cupriavidus necator

A gram-negative, facultatively chemoautotrophic bacterium, formerly called Wautersia eutropha, found in water and soil.


Obstetrical Brachial Plexus Lesion
Obstetrical Brachial Plexus Palsy
Neonatal Brachial Plexus Palsy

Perinatal nerve injury involving the BRACHIAL PLEXUS involving a weak or paralyzed upper extremity.


SFFV
Friend spleen focus-forming virus
Rauscher Spleen Focus-Forming Virus
Spleen Focus-Forming Viruses

Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences.


Thyrocyte
Thyrocytes
Thyroid Epithelial Cells
Thyroid Follicular Cells

Epithelial cells of the THYROID GLAND that produce and secrete THYROXINE and TRIIODOTHYRONINE.


K2Cr2O7
Potassium Dichromate
Potassium Bichromate

Chromic acid (H2Cr2O7), dipotassium salt. A compound having bright orange-red crystals and used in dyeing, staining, tanning leather, as bleach, oxidizer, depolarizer for dry cells, etc. Medically it has been used externally as an astringent, antiseptic, and caustic. When taken internally, it is a corrosive poison.


Host Cell Factor C1
Cell Proliferation Factor HCF
C1 Host Cell Factor
HCFC1 Protein

A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS.  Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.


Diet, Carbohydrate Loading
Carbohydrate Loading
Carbohydrate Loading Diet


Wavelet Signal Processing
Wavelet Analysis
Wavelet Transform
Spatiotemporal Wavelet Analysis

Signal and data processing method that uses decomposition of wavelets to approximate, estimate, or compress signals with finite time and frequency domains. It represents a signal or data in terms of a fast decaying wavelet series from the original prototype wavelet, called the mother wavelet. This mathematical algorithm has been adopted widely in biomedical disciplines for data and signal processing in noise removal and audio/image compression (e.g., EEG and MRI).


Long-Chain 3-Hydroxyacyl CoA Dehydrogenase

An NAD-dependent 3-hydroxyacyl CoA dehydrogenase that has specificity for acyl chains containing 8 and 10 carbons.


A subspecialty of otolaryngology dealing with the parts of the nervous system related to the ear.


Polycystic Kidney and Hepatic Disease 1 (Autosomal Recessive)

Polycystic Kidney Disease, Infantile, Type 1

Polycystic Kidney Disease, Infantile, Type I

Polycystic Kidney Disease, Autosomal Recessive

Autosomal Recessive Polycystic Kidney Disease

A genetic disorder with autosomal recessive inheritance, characterized by multiple CYSTS in both KIDNEYS and associated LIVER lesions. Serious manifestations are usually present at BIRTH with high PERINATAL MORTALITY.


Hyperadrenalism
Hyperadrenocorticism
Hypercorticism
Adrenocortical Hyperfunction
Adrenal Gland Hyperfunction

Excess production of ADRENAL CORTEX HORMONES such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE. Hyperadrenal syndromes include CUSHING SYNDROME; HYPERALDOSTERONISM; and VIRILISM.


Amyotrophy, Thenar, Of Carpal Origin
Carpal Tunnel Syndrome
Median Neuropathy, Carpal Tunnel
Entrapment Neuropathy, Carpal Tunnel
Compression Neuropathy, Carpal Tunnel

Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)


Encephalomyopathies, Mitochondrial
Mitochondrial Encephalomyopathies

A heterogenous group of disorders characterized by alterations of mitochondrial metabolism that result in muscle and nervous system dysfunction. These are often multisystemic and vary considerably in age at onset (usually in the first or second decade of life), distribution of affected muscles, severity, and course. (From Adams et al., Principles of Neurology, 6th ed, pp984-5)


Service, Community Pharmaceutical
Pharmaceutic Services, Community
Service, Community Pharmaceutic
Community Pharmaceutic Services
Community Pharmaceutical Services
Community Pharmacy Services
Services, Community Pharmacy
Pharmaceutical Services, Community
Pharmaceutical Service, Community
Service, Community Pharmacy
Pharmacy Services, Community
Services, Community Pharmaceutic
Services, Community Pharmaceutical

Total pharmaceutical services provided to the public through community pharmacies.


Pyruvate, Pi Dikinase
Pyruvate, Orthophosphate Dikinase
Phosphopyruvate Dikinase
Pyruvate, Phosphate Dikinase

An enzyme that catalyzes the reaction of ATP, pyruvate, and orthophosphate to form AMP plus phosphoenolpyruvate plus pyrophosphate. EC 2.7.9.1.


Evaluation, Work Capacity
Work Capacity Evaluation

Assessment of physiological capacities in relation to job requirements. It is usually done by measuring certain physiological (e.g., circulatory and respiratory) variables during a gradually increasing workload until specific limitations occur with respect to those variables.


Population Genetics
Genetics, Population

The discipline studying genetic composition of populations and effects of factors such as GENETIC SELECTION, population size, MUTATION, migration, and GENETIC DRIFT on the frequencies of various GENOTYPES and PHENOTYPES using a variety of GENETIC TECHNIQUES.


Veterinary Medicine
Medicine, Veterinary

The medical science concerned with the prevention, diagnosis, and treatment of diseases in animals.


Mixed Insulins
Insulin Mixtures
Biphasic Insulin
Biphasic Insulins

An insulin preparation that is designed to provide immediate and long term glycemic control in a single dosage. Biphasic insulin typically contains a mixture of REGULAR INSULIN or SHORT-ACTING INSULIN combined with a LONG-ACTING INSULIN.


Practitioners, Infection Control
Infection Control Practitioners
Practitioner, Infection Control
Infection Control Practitioner

Physicians or other qualified individuals responsible for implementing and overseeing the policies and procedures followed by a health care facility to reduce the risk of infection to patients and staff.


Dominant Hereditary Sensory Neuropathy, Type III

HSAN (Hereditary Sensory and Autonomic Neuropathy) Type III

Neuropathy, Hereditary Sensory And Autonomic, Type III

Hereditary Sensory Neuropathy, Dominant, Type III

Neuropathy, Hereditary and Autonomic, Type III

Hereditary Sensory Neuropathy, Type 3, Dominant

Type III Hereditary Sensory Neuropathy, Dominant

Hereditary Sensory Neuropathy, Dominant, Type 3

Hereditary-Sensory and Autonomic Neuropathy Type III

Hereditary Sensory and Autonomic Neuropathy 3

Type 3 Hereditary Sensory Neuropathy, Dominant

An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)


Histidine alpha-Deaminase
Histidine Ammonia-Lyase
Histidase
Histidinase
Histidine Deaminase

An enzyme that catalyzes the first step of histidine catabolism, forming UROCANIC ACID and AMMONIA from HISTIDINE. Deficiency of this enzyme is associated with elevated levels of serum histidine and is called histidinemia (AMINO ACID METABOLISM, INBORN ERRORS).


Injuries, Spinal Cord
Spinal Cord Trauma
Spinal Cord Transection
Spinal Cord Laceration
Spinal Cord Injuries
Spinal Cord Contusion
Myelopathy, Traumatic
Post-Traumatic Myelopathy

Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).


A plant genus of the family ASTERACEAE. Some Rudbeckia species have been reclassified to ECHINACEA; RATIBIDA; or HELIANTHUS.


NAD-Formate Dehydrogenase
Formate Dehydrogenases
Formate Hydrogenlyases

Flavoproteins that catalyze reversibly the reduction of carbon dioxide to formate. Many compounds can act as acceptors, but the only physiologically active acceptor is NAD. The enzymes are active in the fermentation of sugars and other compounds to carbon dioxide and are the key enzymes in obtaining energy when bacteria are grown on formate as the main carbon source. They have been purified from bovine blood. EC 1.2.1.2.


Euploid male germ cells of an early stage of SPERMATOGENESIS, derived from prespermatogonia. With the onset of puberty, spermatogonia at the basement membrane of the seminiferous tubule proliferate by mitotic then meiotic divisions and give rise to the haploid SPERMATOCYTES.


The capacity of an organism to defend itself against pathological processes or the agents of those processes. This most often involves innate immunity whereby the organism responds to pathogens in a generic way. The term disease resistance is used most frequently when referring to plants.


Encephalopathy, Subacute Spongiform, Gerstmann-Straussler Type

Gerstmann-Straussler Inherited Spongiform Encephalopathy

Inherited Spongiform Encephalopathy, Gerstmann-Straussler

An autosomal dominant familial prion disease with a wide spectrum of clinical presentations including ATAXIA, spastic paraparesis, extrapyramidal signs, and DEMENTIA. Clinical onset is in the third to sixth decade of life and the mean duration of illness prior to death is five years. Several kindreds with variable clinical and pathologic features have been described. Pathologic features include cerebral prion protein amyloidosis, and spongiform or neurofibrillary degeneration. (From Brain Pathol 1998 Jul;8(3):499-513; Brain Pathol 1995 Jan;5(1):61-75)


Thesaurismosis
Metabolic Diseases
Diseases, Metabolic

Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)


Heme Oxygenase (Decyclizing)
Haem Oxygenase
Heme Oxygenase

A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt.


gsk-3 Gene Product
GSK-3
Glycogen Synthase Kinase 3

A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabolism. It regulates a diverse array of functions such as CELL DIVISION, microtubule function and APOPTOSIS.


Drusen, Optic Nerve
Optic Disk Drusen
Optic Disc Drusen
Drusen, Optic Disc
Drusen, Optic Disk

Optic disk bodies composed primarily of acid mucopolysaccharides that may produce pseudopapilledema (elevation of the optic disk without associated INTRACRANIAL HYPERTENSION) and visual field deficits. Drusen may also occur in the retina (see RETINAL DRUSEN). (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p355)


Pneumocystis jirovecii Pneumonia
Pneumocystis Pneumonia
Pneumonia, Pneumocystis carinii
Pneumocystis carinii Pneumonia
PCP Infection
Pneumocystosis
Pneumonia, Interstitial Plasma Cell
Pneumonia, Pneumocystis

A pulmonary disease in humans occurring in immunodeficient or malnourished patients or infants, characterized by DYSPNEA, tachypnea, and HYPOXEMIA. Pneumocystis pneumonia is a frequently seen opportunistic infection in AIDS. It is caused by the fungus PNEUMOCYSTIS JIROVECII. The disease is also found in other MAMMALS where it is caused by related species of Pneumocystis.


Temperature Regulation, Body
Body Temperature Regulation
Regulation, Body Temperature
Thermoregulation
Heat Loss

The processes of heating and cooling that an organism uses to control its temperature.


Hepatitis C virus
Hepatitis C-Like Viruses
Hepacivirus

Six clades of the virus exist. But all are considered one species, since serotyping is not yet possible and they do not contain any other taxonomic characteristics except geographic distribution (8th ICTV Report).


Stress Disorders, Traumatic, Acute
Stress Disorders, Acute
Acute Stress Disorders

A class of traumatic stress disorders that is characterized by the significant dissociative states seen immediately after overwhelming trauma. By definition it cannot last longer than 1 month, if it persists, a diagnosis of post-traumatic stress disorder (STRESS DISORDERS, POST-TRAUMATIC) is more appropriate.


A type I keratin that is found associated with the KERATIN-5 in the internal stratified EPITHELIUM. Mutations in the gene for keratin-14 are associated with EPIDERMOLYSIS BULLOSA SIMPLEX.


Magnetic Resonance Guided Interventional Procedures

Magnetic Resonance Imaging, Interventional

Interventional Magnetic Resonance Imaging

Minimally invasive procedures guided with the aid of magnetic resonance imaging to visualize tissue structures.


A lipocalin of approximately 200 amino acids that functions as an iron transporter and is expressed by cells of BONE MARROW and many other cells with secretory functions. It is involved in APOPTOSIS and may function to limit pathogenic bacterial growth as part of the INNATE IMMUNE RESPONSE.


Insulin-Like Growth Factor Binding Protein 5

One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.


A family of structurally related neurotoxic peptides from mollusk venom that inhibit voltage-activated entry of calcium into the presynaptic membrane. They selectively inhibit N-, P-, and Q-type calcium channels.


Optic Chiasm
Chiasma Opticum
Optic Decussation
Optic Chiasma

The X-shaped structure formed by the meeting of the two optic nerves. At the optic chiasm the fibers from the medial part of each retina cross to project to the other side of the brain while the lateral retinal fibers continue on the same side. As a result each half of the brain receives information about the contralateral visual field from both eyes.


Receptors, Immunologic
Immunologic Receptors
Immunologic Receptor
Immunological Receptors

Cell surface molecules on cells of the immune system that specifically bind surface molecules or messenger molecules and trigger changes in the behavior of cells. Although these receptors were first identified in the immune system, many have important functions elsewhere.


Anastomosis, Cavopulmonary
Cavopulmonary Shunt
Cavopulmonary Anastomosis
Bypass, Right Heart
Right Heart Bypass
Shunt, Cavopulmonary
Heart Bypass, Right

Diversion of the flow of blood from the entrance to the right atrium directly to the pulmonary arteries, avoiding the right atrium and right ventricle (Dorland, 28th ed). This a permanent procedure often performed to bypass a congenitally deformed right atrium or right ventricle.


Atypical Bacterial Forms
Bacterial Forms, Atypical

Microorganisms that have undergone greater changes than normal in morphology, physiology, or cultural characteristics.


Tumor Necrosis Factor Superfamily Ligands

A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS.


Bronchiole
Respiratory Bronchioles
Bronchioles
Terminal Bronchioles

The small airways branching off the TERTIARY BRONCHI. Terminal bronchioles lead into several orders of respiratory bronchioles which in turn lead into alveolar ducts and then into PULMONARY ALVEOLI.


A branch of medicine concerned with the total health of the individual within the home environment and in the community, and with the application of comprehensive care to the prevention and treatment of illness in the entire community.


A diet typical of the Mediterranean region characterized by a pattern high in fruits and vegetables, EDIBLE GRAIN and bread, potatoes, poultry, beans, nuts, olive oil and fish while low in red meat and dairy and moderate in alcohol consumption.


Recombinant Human TSH
Thyrogen
Thyrotropin Alfa
rhTSH

A highly purified recombinant glycoprotein form of human THYROID-STIMULATING HORMONE, produced by recombinant DNA technology comprising two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites, and a beta subunit of 118 residues containing one N-linked glycosylation site. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone.


Organic sulfonic acid esters or salts which contain an aromatic hydrocarbon radical.


Day Care Center, Adult
Adult Day Care Centers
Adult Day Care Center
Day Care Centers, Adult

Non-residential facilities that are designed to provide care and companionship for seniors who need assistance or supervision during the day.


alpha 1-Antichymotrypsin
alpha(1)-Antichymotrypsin
Serpin A3

Glycoprotein found in alpha(1)-globulin region in human serum. It inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. It is a member of the serpin superfamily.


Biochemistry, Inorganic
Biological Inorganic Chemistry
Chemistry, Bioinorganic
Bioinorganic Chemistry

Field of chemistry pertaining to the study of inorganic compounds or ions and their interactions with biological ligands at the molecular level.


Teeth Bleaching Agents
Tooth Whitening Agents
Tooth Bleaching Agents
Teeth Whitening Agents

Chemicals that are used to oxidize pigments in TEETH and thus effect whitening.


Acetylcholine Agonist
Cholinergic Agonists
Acetylcholine Agonists
Cholinergic Agonist

Drugs that bind to and activate cholinergic receptors.


Ehrlich Ascites Tumor
Carcinoma, Ehrlich Tumor

A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.


DMPK Protein
DM Protein Kinase
Myotonic Dystrophy Protein Kinase
MDGP Protein
DM1PK Protein
DM-Kinase
MDPK Protein
Myotonin-Protein Kinase

Serine/threonine protein kinase responsible for various SKELETAL MUSCLE functions; HEART CONDUCTION SYSTEM activity; calcium HOMEOSTASIS; calcium uptake by SARCOPLASMIC RETICULUM and SYNAPTIC PLASTICITY. It is encoded by the DMPK gene and its abnormal EXPANDED TRINUCLEOTIDE REPEAT of CTG in the 3'-UTR is associated with MYOTONIC DYSTROPHY 1.


Lower Extremity Deformities, Congenital
Lower Limb Deformities, Congenital

Congenital structural abnormalities of the LOWER EXTREMITY.


A member of the alkali metals. It has an atomic symbol Cs, atomic number 50, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency.


Purkinje Neuron
Purkyne Cell
Purkinje Cell
Purkinje Cells

The output neurons of the cerebellar cortex.


A specific pair of GROUP C CHROMOSOMES of the human chromosome classification.


Deoxycytidylate Deaminase
DCMP Deaminase
Deoxycytidylate Aminohydrolase
Deoxycytidine Monophosphate Deaminase

An enzyme that catalyzes the hydrolytic deamination of deoxycytidylic acid to deoxyuridylic acid and ammonia. It plays an important role in the regulation of the pool of deoxynucleotides in higher organisms. The enzyme also acts on some 5-substituted deoxycytidylic acids. EC 3.5.4.12.


Serotonin 5-HT3 Receptor Agonists
5-HT3 Agonist
5-HT3 Agonists

Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT3 RECEPTORS.


Sequences, Intervening
Introns
Intervening Sequences

Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.


Mental Retardation, X-Linked
X-Linked Mental Retardation Syndromes
X-Linked Mental Retardation
X-Linked Mental Retardation Disorders

A class of genetic disorders resulting in INTELLECTUAL DISABILITY that is associated either with mutations of GENES located on the X CHROMOSOME or aberrations in the structure of the X chromosome (SEX CHROMOSOME ABERRATIONS).


Delta Virus
Deltavirus
Delta Agent
Hepatitis Delta Virus
Hepatitis D Virus

This is a free-floating genus with one species (HEPATITIS DELTA VIRUS) and no associated family.


Collateral Ligament, Ulnar
Ulnar Collateral Ligament

The internal lateral ligament that travels from the medial aspect of the ELBOW uniting the distal aspect of the HUMERUS to the proximal aspect of the ULNA.


Chemokine CXCL16
SR-PSOX
CXC Chemokine Ligand 16

A CXCR6 receptor-binding chemokine that functions as a scavenger receptor for oxidized low density lipoprotein (OxLDL) when expressed by MACROPHAGES. Its secreted, or cytokine form induces a strong chemotactic response for MONOCYTES when it is expressed by DENDRITIC CELLS.


IFN-Regulatory Factor 3
Interferon Regulatory Factor-3
IRF-3 Transcription Factor

An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.


Ribosome Subunits, Large
Large Ribosome Subunits
Ribosomal Subunits, Large
Large Ribosomal Subunits

The largest ribonucleoprotein component of RIBOSOMES. It contains the domains which catalyze formation of the peptide bond and translocation of the ribosome along the MESSENGER RNA during GENETIC TRANSLATION.


Oral Hairy Leukoplakia
Leukoplakia, Hairy
Leukoplakia, Hairy, Oral

Epithelial hyperplasia of the oral mucosa associated with Epstein-Barr virus (HERPESVIRUS 4, HUMAN) and found almost exclusively in persons with HIV infection. The lesion consists of a white patch that is often corrugated or hairy.


The decarboxylation product of UDPglucuronic acid, which is used for formation of the xylosides of seryl hydroxyl groups in mucoprotein synthesis. Also forms plant xylans.


The acoustic aspects of speech in terms of frequency, intensity, and time.


White Fat Cells
White Adipocytes
Adipocytes, White

Fat cells with light coloration and few MITOCHONDRIA. They contain a scant ring of CYTOPLASM surrounding a single large lipid droplet or vacuole.


Antazoline Phosphate
Arithmin
Antazoline Hydrochloride
Antazoline
Imidamine
Antistine
Phenazoline
Antasten
Analergine
Antazoline Phosphate (1:1)

An antagonist of histamine H1 receptors.


Shadow Test
Retinoscopy
Skiascopy
Skiametry

An objective determination of the refractive state of the eye (NEARSIGHTEDNESS; FARSIGHTEDNESS; ASTIGMATISM). By using a RETINOSCOPE, the amount of correction and the power of lens needed can be determined.


Homografts, Isogeneic
Isografts
Homografts, Syngeneic

Tissues, cells or organs transplanted between genetically identical individuals, i.e. members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains.


Hypersensitivity Pneumonitis
Alveolitis, Extrinsic Allergic
Pneumonitis, Hypersensitivity
Allergic Alveolitis, Extrinsic

A common interstitial lung disease caused by hypersensitivity reactions of PULMONARY ALVEOLI after inhalation of and sensitization to environmental antigens of microbial, animal, or chemical sources. The disease is characterized by lymphocytic alveolitis and granulomatous pneumonitis.


Abnormality, Torsion
Torsion Abnormality

An abnormal twisting or rotation of a bodily part or member on its axis.


Monitoring, Ambulatory
Outpatient Monitoring
Ambulatory Monitoring
Monitoring, Outpatient

The use of electronic equipment to observe or record physiologic processes while the patient undergoes normal daily activities.


beta-Crystallin Basic Principal Polypeptide


Neurosurgical Procedures
Procedures, Neurosurgical
Surgical Procedures, Neurologic

Surgery performed on the nervous system or its parts.


Wards, General
Semi-Private Rooms
Private Rooms
Patients' Rooms
Rooms, Patient

Rooms occupied by one or more individuals during a stay in a health facility. The concept includes aspects of environment, design, care, or economics.


National Institute on Deafness and Other Communication Disorders (U.S.)

Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports biomedical research and research training on normal mechanisms as well as diseases and disorders of hearing, balance, smell, taste, voice, speech, and language. It was established in 1988.


Congenital Enamel Hypoplasia
Amelogenesis Imperfecta

A clinically and genetically heterogeneous group of hereditary conditions characterized by malformed DENTAL ENAMEL, usually involving DENTAL ENAMEL HYPOPLASIA and/or TOOTH HYPOMINERALIZATION.


Concepts, definitions, and propositions applied to the study of various phenomena which pertain to nursing and nursing research.


A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.


Hexonium
Hexamethonium Chloride
Hexamethonium Diperchlorate
Hexamethonium Dihydroxide
Hexamethonium Bitartrate
Hexamethonium Dimethylsulfate
Hexamethonium Monotartrate
Hexamethonium Dibromide
Hexamethonium Dichloride Dihydrate
Hexamethonium Dibromide Dihydrate
Hexamethonium Bromide
Hexamethonium Diiodide
Hexamethonium
Hexamethonium Iodide
Depressin

A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.


Lymph Node Excision
Lymphadenectomy
Lymph Node Dissection

Surgical excision of one or more lymph nodes. Its most common use is in cancer surgery. (From Dorland, 28th ed, p966)


B Lymphocyte-Induced Maturation Protein 1

Positive Regulatory Domain I-Binding Factor 1

A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.


Derived proteins or mixtures of cleavage products produced by the partial hydrolysis of a native protein either by an acid or by an enzyme. Peptones are readily soluble in water, and are not precipitable by heat, by alkalis, or by saturation with ammonium sulfate. (Dorland, 28th ed)


National Institute on Drug Abuse (U.S.)
NIDA (US)
National Institute on Drug Abuse

Component of the NATIONAL INSTITUTES OF HEALTH. It supports a comprehensive research portfolio that focuses on the biological, social, behavioral and neuroscientific bases of drug abuse on the body and brain as well as its causes, prevention, and treatment. NIDA, NIAAA, and NIMH were created as coequal institutes within the Alcohol, Drug Abuse and Mental Health Administration in 1974. It was established within the NATIONAL INSTITUTES OF HEALTH in 1992.


An enzyme that catalyzes the formation of UDPglucose from UTP plus glucose 1-phosphate. EC 2.7.7.9.


Anesthetics, General
General Anesthetics

Agents that induce various degrees of analgesia; depression of consciousness, circulation, and respiration; relaxation of skeletal muscle; reduction of reflex activity; and amnesia. There are two types of general anesthetics, inhalation and intravenous. With either type, the arterial concentration of drug required to induce anesthesia varies with the condition of the patient, the desired depth of anesthesia, and the concomitant use of other drugs. (From AMA Drug Evaluations Annual, 1994, p.173)


Inorganic or organic compounds that contain arsenic.


This line KB is now known to be a subline of the ubiquitous KERATIN-forming tumor cell line HeLa. It was originally thought to be derived from an epidermal carcinoma of the mouth, but was subsequently found, based on isoenzyme analysis, HeLa marker chromosomes, and DNA fingerprinting, to have been established via contamination by HELA CELLS. The cells are positive for keratin by immunoperoxidase staining. KB cells have been reported to contain human papillomavirus18 (HPV-18) sequences.


Rejection, Transplant
Graft Rejection
Transplantation Rejection
Transplant Rejection

An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.


Ureteral Colic
Acute Renal Colic
Renal Colic

A severe intermittent and spasmodic pain in the lower back radiating to the groin, scrotum, and labia which is most commonly caused by a kidney stone (RENAL CALCULUS) passing through the URETER or by other urinary track blockage. It is often associated with nausea, vomiting, fever, restlessness, dull pain, frequent urination, and HEMATURIA.


Pantothenic Acid
Vitamin B 5
Calcium Pantothenate
Dexol
Zinc Pantothenate
Vitamin B5

A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE.


5' Capped RNA
5' mRNA Cap Structure
RNA Caps

Nucleic acid structures found on the 5' end of eukaryotic cellular and viral messenger RNA and some heterogeneous nuclear RNAs. These structures, which are positively charged, protect the above specified RNAs at their termini against attack by phosphatases and other nucleases and promote mRNA function at the level of initiation of translation. Analogs of the RNA caps (RNA CAP ANALOGS), which lack the positive charge, inhibit the initiation of protein synthesis.


Zinc Glycyrrhizate
Diammonium Glycyrrhizinate
Glycyrrhizin
Glycyrrhizinic Acid
Glycyrrhizic Acid
Dipotassium Glycyrrhizinate

A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.


Computer Data Processing
Bar Codes
Information Processing, Automatic
Data Processing, Automatic
Information Processing
Optical Readers
Automatic Data Processing
Electronic Data Processing

Applications that store and process large quantities of data.


Gastrin Pentapeptide
Peptavlon
Pentagastrin
Acignost

A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.


Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.


beta-Alanine
beta-Alanine Hydrochloride
3-Aminopropionic Acid
beta-Alanine, Monopotassium Salt
beta-Alanine, Calcium Salt (2:1)
beta-Alanine, Monosodium Salt

An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.


Proton-translocating ATPases responsible for ADENOSINE TRIPHOSPHATE synthesis in the MITOCHONDRIA. They derive energy from the respiratory chain-driven reactions that develop high concentrations of protons within the intermembranous space of the mitochondria.


Coinsurance
Coinsurance and Deductibles
Deductibles and Coinsurance
Deductibles

Cost-sharing mechanisms that provide for payment by the insured of some portion of covered expenses. Deductibles are the amounts paid by the insured under a health insurance contract before benefits become payable; coinsurance is the provision under which the insured pays part of the medical bill, usually according to a fixed percentage, when benefits become payable.


Paired-Box Protein, PAX8
PAX8 Transcription Factor

A paired box transcription factor that functions in the development of THYROCYTES and the control of thyroid-specific gene expression. Mutations in the PAX8 gene are associated with THYROID DYSGENESIS and THYROID NEOPLASMS.


Chemical Engineering
Engineering, Chemical

Application of principles and practices of engineering science to the transformation, design, and manufacture of substances on an industrial scale.


Median Forebrain Bundle
Medial Forebrain Bundle

A complex group of fibers arising from the basal olfactory regions, the periamygdaloid region, and the septal nuclei, and passing to the lateral hypothalamus. Some fibers continue into the tegmentum.


Dual Specificity Mitogen-Activated Protein Kinase Kinase 3

A mitogen-activated protein kinase kinase with specificity for a subset of P38 MITOGEN-ACTIVATED PROTEIN KINASES that includes MITOGEN-ACTIVATED PROTEIN KINASE 12; MITOGEN-ACTIVATED PROTEIN KINASE 13; and MITOGEN-ACTIVATED PROTEIN KINASE 14.


Neotrombicula
Chiggers
Trombiculid Mites
Red Bugs
Eutrombicula
Trombiculidae
Harvest Mites
Trombicula
Leptotrombidium

A genus of MITES in the family TROMBICULIDAE, whose larvae cause and carry disease. The larvae attack humans and other vertebrates, causing dermatitis and severe allergic reactions. Adult forms do not bite. Species of the subgenera Leptotrombidium are the carriers of SCRUB TYPHUS.


FSH Receptor
Receptors, FSH
Receptors, Follicle-Stimulating Hormone
FSH Receptors
Follicle-Stimulating Hormone Receptor
Follicle-Stimulating Hormone Receptors

Cell surface proteins that bind FOLLICLE STIMULATING HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells.


alpha-Lipoproteins
alpha-1 Lipoprotein
Lipoproteins, HDL
High-Density Lipoproteins
Heavy Lipoproteins

A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.


An acute febrile human disease caused by the LASSA VIRUS.


Von Ebner's Gland Protein
Lipocalin LCN1
Tear Lipocalin
Von Ebner Gland Protein
Tear Prealbumin Protein
Lipocalin 1

A lipocalin that was orignally characterized from human TEARS. It is expressed primarily in the LACRIMAL GLAND and the VON EBNER GLANDS. Lipocalin 1 may play a role in olfactory transduction by concentrating and delivering odorants to the ODORANT RECEPTORS.


Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.


Pour Plate Count
Spread Plate Count
Streak Plate Count
Colony Forming Units Assay, Microbial
Colony-Forming Units Assay, Microbial
Colony Count, Microbial
Colony Forming Units Assays, Microbial
Agar Dilution Count
Fungal Count
Spore Count

Enumeration by direct count of viable, isolated bacterial, archaeal, or fungal CELLS or SPORES capable of growth on solid CULTURE MEDIA. The method is used routinely by environmental microbiologists for quantifying organisms in AIR; FOOD; and WATER; by clinicians for measuring patients' microbial load; and in antimicrobial drug testing.


Genetic Diseases, Y-Chromosome Linked
Genetic Diseases, Y-Linked
Y-Linked Genetic Diseases

Genetic diseases that are linked to mutant ALLELES on the Y CHROMOSOME in humans (Y CHROMOSOME, HUMAN) or the Y chromosome in other species. Included here are animal models of human Y-linked diseases.


An albumin obtained from the white of eggs. It is a member of the serpin superfamily.


Fibrin Modulators
Fibrin Modulating Agents

Agents that affect the function of FIBRIN in BLOOD COAGULATION. They used as COAGULANTS for HEMORRHAGE or ANTICOAGULANTS for THROMBOSIS.


Water naturally or artificially infused with mineral salts or gases.


GATA6 Transcription Factor
GATA-6 Transcription Factor
Transcription Factor GATA6
Transcription Factor GATA-6

A GATA transcription factor that is expressed predominately in SMOOTH MUSCLE CELLS and regulates vascular smooth muscle CELL DIFFERENTIATION.


Paracrine Communication
Paracrine Signaling

Cellular signaling in which a factor secreted by a cell affects other cells in the local environment. This term is often used to denote the action of INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS on surrounding cells.