Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted. [GOC:dph]


Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. [GOC:dph]


negative regulation of prostatic bud formation

Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. [GOC:dph]


regulation of branching involved in prostate gland morphogenesis

Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. [GOC:dph]


regulation of morphogenesis of a branching structure

Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. [GOC:dph]


cell differentiation involved in salivary gland development

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland. [GOC:dph]


epithelial cell differentiation involved in salivary gland development

The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland. [GOC:dph]


epithelial cell maturation involved in salivary gland development

The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state. [GOC:dph]


mesenchymal cell differentiation involved in salivary gland development

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. [GOC:dph]


regulation of branching involved in salivary gland morphogenesis

Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium. [GOC:dph]


regulation of cholesterol transporter activity

Any process that modulates the rate, frequency, or extent of cholesterol transporter activity. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of cholesterol transporter activity

Any process that decreases the rate, frequency, or extent of cholesterol transporter activity. [GOC:BHF, GOC:dph, GOC:tb]


regulation of phospholipid catabolic process

Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of phospholipid catabolic process

Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. [GOC:BHF, GOC:dph, GOC:tb]


Binds to and stops, prevents or reduces the activity of endoribonuclease. [GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. [GOC:dph, GOC:tb]


Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. [GOC:dph, GOC:tb]


negative regulation of ribonuclease activity

Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. [GOC:dph, GOC:tb]


negative regulation of endoribonuclease activity

Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. [GOC:dph, GOC:tb]


Binds to and stops, prevents or reduces the activity of deoxyribonuclease. [GOC:dph, GOC:tb]


acinar cell differentiation involved in salivary gland development

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland. [GOC:dph, GOC:tb]


neuron differentiation involved in salivary gland development

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland. [GOC:dph]


cell differentiation involved in embryonic placenta development

The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta. [GOC:dph]


The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua. [GOC:dph, PMID:16269175]


The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell. [GOC:dph, PMID:16269175]


The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois. [GOC:dph]


The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state. [GOC:dph]


The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state. [GOC:dph]


The process in which the labyrinthine layer of the placenta is generated and organized. [GOC:dph]


The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta. [GOC:dph]


syncytiotrophoblast cell differentiation involved in labyrinthine layer development

The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta. [GOC:dph]


labyrinthine layer blood vessel development

The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply. [GOC:dph]


The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane. [GOC:dph]


chorionic trophoblast cell differentiation

The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. [CL:0011101, GOC:dph, PMID:16983341]


The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. [CL:0011101, GOC:16983341, GOC:dph]


The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer. [GOC:dph]


regulation of spongiotrophoblast cell proliferation

Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation. [GOC:dph]


cell proliferation involved in embryonic placenta development

The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta. [GOC:dph]


regulation of cell proliferation involved in embryonic placenta development

Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development. [GOC:dph]


coreceptor activity involved in epidermal growth factor receptor signalling pathway

coreceptor activity involved in epidermal growth factor receptor signaling pathway

Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway. [GOC:dph, GOC:tb]


Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity. [GOC:dph, GOC:tb]


regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway

regulation of Neu/ErbB-2 receptor activity

regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway

Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. [GOC:dph, GOC:tb]


positive regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway

positive regulation of Neu/ErbB-2 receptor activity

positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway

Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. [GOC:dph, GOC:tb]


negative regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway

negative regulation of Neu/ErbB-2 receptor activity

negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway

Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway. [GOC:dph, GOC:tb]


epithelial structure maintenance of intestine

intestinal epithelial structure maintenance

A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. [GOC:BHF, GOC:dph, GOC:tb]


regulation of intestinal epithelial structure maintenance

Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of intestinal epithelial structure maintenance

Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium. [GOC:dph, GOC:tb]


positive regulation of inositol phosphate biosynthetic process

Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. [GOC:dph, GOC:tb]


regulation of ER stress-induced eIF2 alpha phosphorylation

regulation of eIF2 alpha phosphorylation by ER stress

regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress

regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress. [GOC:dph, GOC:tb]


regulation of eIF2 alpha phosphorylation by double-stranded RNA

regulation of eIF2 alpha phosphorylation by dsRNA

Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA. [GOC:dph, GOC:tb]


regulation of eIF2 alpha phosphorylation by PKR


The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state. [GOC:dph]


prostate gland growth involved in morphogenesis

The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form. [GOC:dph]


mesenchymal-epithelial cell signalling involved in prostate gland development

mesenchymal-epithelial cell signaling involved in prostate gland development

Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time. [GOC:dph]


The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. [GOC:dph]


The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland. [GOC:dph]


epithelial cell differentiation involved in prostate gland development

The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland. [GOC:dph]


prostate gland epithelial cell development

epithelial cell maturation involved in prostate gland development

The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. [GOC:dph]


mammary gland branching involved in puberty

mammary gland branching involved in thelarche

The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. [GOC:dph, PMID:19261859]


mammary gland branching involved in pregnancy

The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy. [GOC:dph, PMID:19261859]


A reproductive behavior in which a parent cares for and rears offspring. [GOC:dph]


A parental behavior in which fertilized eggs are taken into the mouth and held until hatching. [GOC:dph]


tertiary branching involved in mammary gland duct morphogenesis

The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy. [GOC:dph, PMID:18614704]


The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland. [GOC:dph]


epithelial cell proliferation involved in mammary gland duct elongation

The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth. [GOC:dph]


branch elongation involved in mammary gland duct branching

The developmental growth process in which a branch of a mammary gland duct elongates. [GOC:dph]


Any process in which phytosterols are taken up from the contents of the intestine. [GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. [GOC:dph, GOC:tb]


positive regulation of mast cell chemotaxis

Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. [GOC:dph, GOC:tb]


negative regulation of mast cell chemotaxis

Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus. [GOC:dph, GOC:tb]


Behavior by which an organism locates food. [GOC:dph, GOC:tb]


Behavior by which an adult locates food. [GOC:dph, GOC:tb]


Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food. [GOC:dph, GOC:tb]


regulation of response to cytokine stimulus

Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of response to cytokine stimulus

Any process that increases the rate, frequency, or extent of a response to cytokine stimulus. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of response to cytokine stimulus

Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus. [GOC:BHF, GOC:dph, GOC:tb]


regulation of branching involved in mammary gland duct morphogenesis

Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis. [GOC:dph]


The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty. [GOC:dph, PMID:10804170]


cell-cell signalling involved in mammary gland development

cell-cell signaling involved in mammary gland development

Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure. [GOC:dph]


regulation of androgen receptor signalling pathway

regulation of androgen receptor signaling pathway

Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway. [GOC:dph]


negative regulation of androgen receptor signalling pathway

negative regulation of androgen receptor signaling pathway

Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway. [GOC:dph]


epithelial cell proliferation involved in prostate gland development

The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. [GOC:dph]


regulation of epithelial cell proliferation involved in prostate gland development

Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. [GOC:dph]


positive regulation of epithelial cell proliferation involved in prostate gland development

Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. [GOC:dph]


negative regulation of epithelial cell proliferation involved in prostate gland development

Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. [GOC:dph]


The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem. [GOC:dph, GOC:sdb_2009, GOC:tb]


The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium. [GOC:dph, GOC:sdb_2009, GOC:tb]


auxin mediated signalling pathway involved in phyllotactic patterning

auxin mediated signaling pathway involved in phyllotactic patterning

The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem. [GOC:dph, GOC:sdb_2009, GOC:tb]


planar cell polarity pathway involved in gastrula mediolateral intercalation

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation. [GOC:dph, GOC:sdb_2009, GOC:tb]


The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided. [GOC:dph, GOC:sdb_2009, GOC:tb]


The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets. [GOC:dph, GOC:sdb_2009, GOC:tb]


mesenchymal cell proliferation involved in prostate gland development

The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. [GOC:dph, PMID:12221011]


regulation of mesenchymal cell proliferation involved in prostate gland development

Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. [GOC:dph, PMID:12221011]


mesenchymal smoothened signalling pathway involved in prostate gland development

mesenchymal hedgehog signaling pathway involved in prostate gland development

mesenchymal hh signaling pathway involved in prostate gland development

mesenchymal smoothened signaling pathway involved in prostate gland development

The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development. [PMID:12221011]


regulation of cell proliferation involved in tissue homeostasis

Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue. [GOC:dph]


regulation of apoptosis involved in tissue homeostasis

Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue. [GOC:dph]


regulation of cell differentiation involved in tissue homeostasis

Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue. [GOC:dph]


positive regulation of posterior neural plate formation by fibroblast growth factor receptor signalling pathway

positive regulation of posterior neural plate formation by FGF receptor signaling pathway

positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway

Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate. [GOC:dph, GOC:sdb_2009, GOC:tb]


The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. [GOC:dph, GOC:sdb_2009, GOC:tb]


The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. [GOC:dph, GOC:sdb_2009, GOC:tb]


The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud. [GOC:dph, GOC:sdb_2009, GOC:tb]


The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud. [GOC:dph, GOC:sdb_2009, GOC:tb]


The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation. [GOC:dph, GOC:sdb_2009, GOC:tb]


The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which the anatomical structures of the leaflet are generated and organized. [GOC:dph, GOC:sdb_2009, GOC:tb]


cell fate commitment involved in formation of primary germ layer

The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. [GOC:dph, GOC:sdb_2009, GOC:tb]


transforming growth factor beta receptor signalling pathway involved in primary germ layer cell fate commitment

transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment

The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate. [GOC:dph, GOC:sdb_2009, GOC:tb]


transforming growth factor beta receptor signalling pathway involved in mesodermal cell fate specification

transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification

The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate. [GOC:dph, GOC:sdb_2009, GOC:tb]


transforming growth factor beta receptor signalling pathway involved in endodermal cell fate specification

transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification

The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate. [GOC:dph, GOC:sdb_2009, GOC:tb]


regulation of cell differentiation involved in embryonic placenta development

Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. [GOC:dph, GOC:sdb_2009, GOC:tb]


negative regulation of trophoblast cell differentiation by transforming growth factor beta signalling pathway

negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway

The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast. [GOC:dph, GOC:sdb_2009, GOC:tb]


epiblast cell-extraembryonic ectoderm cell signalling involved in anterior/posterior axis specification

epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification

Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


BMP signalling pathway involved in mesodermal cell fate specification

BMP signaling pathway involved in mesodermal cell fate specification

The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate. [GOC:dph, GOC:sdb_2009, GOC:tb]


positive regulation of WNT receptor signaling pathway by BMP signaling pathway

positive regulation of WNT receptor signalling pathway by BMP signalling pathway

positive regulation of Wnt-activated signaling pathway by BMP signaling pathway

positive regulation of Wnt signaling pathway by BMP signaling pathway

The series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway. [GOC:dph, GOC:sdb_2009, GOC:tb]


negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter

Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast. [GOC:dph, GOC:sdb_2009, GOC:tb]


negative regulation of cell differentiation involved in embryonic placenta development

Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. [GOC:dph, GOC:sdb_2009, GOC:tb]


positive regulation of mesodermal to mesenchymal transition involved in gastrulation

Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation. [GOC:dph, GOC:sdb_2009, GOC:tb]


mesodermal to mesenchymal transition involved in gastrulation

The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation. [GOC:dph, GOC:sdb_2009, GOC:tb]


intracellular mRNA localisation involved in pattern specification process

intracellular mRNA localization involved in pattern specification process

Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo. [GOC:dph, GOC:sdb_2009, GOC:tb]


intracellular mRNA localisation involved in anterior/posterior axis specification

intracellular mRNA localization involved in anterior/posterior axis specification

Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


anterior mRNA localisation involved in anterior/posterior axis specification

anterior mRNA localization involved in anterior/posterior axis specification

Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


posterior mRNA localisation involved in anterior/posterior axis specification

posterior mRNA localization involved in anterior/posterior axis specification

Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


regulation of translation involved in anterior/posterior axis specification

Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex. [GOC:dph, GOC:sdb_2009, GOC:tb]


Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex. [GOC:dph, GOC:sdb_2009, GOC:tb]


inactivation of paternal X chromosome by genetic imprinting


inactivation of X chromosome by genetic imprinting


inactivation of X chromosome by heterochromatin formation

inactivation of X chromosome by heterochromatin assembly

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation. [GOC:dph, GOC:sdb_2009, GOC:tb]


transforming growth factor beta receptor signalling pathway involved in axial mesodermal cell fate specification

transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification

The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate. [GOC:dph, GOC:sdb_2009, GOC:tb]


canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation

canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation

Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation

canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation

canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern. [GOC:dph, GOC:sdb_2009, GOC:tb]


retinoic acid receptor signalling pathway involved in neural plate anterior/posterior pattern formation

retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate. [GOC:dph, GOC:sdb_2009, GOC:tb]


fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation

fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate. [GOC:dph, GOC:sdb_2009, GOC:tb]


transforming growth factor beta receptor signalling pathway involved in neural plate anterior/posterior pattern formation

transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation

The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern. [GOC:dph, GOC:sdb_2009, GOC:tb]


regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation

regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation

regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation

regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation

regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern. [GOC:dph, GOC:sdb_2009, GOC:tb]


regulation of Wnt receptor signaling pathway through beta-catenin

regulation of canonical Wnt receptor signaling pathway

regulation of canonical Wnt receptor signalling pathway

regulation of canonical Wnt-activated signaling pathway

regulation of canonical Wnt signaling pathway

Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:dph, GOC:sdb_2009, GOC:tb]


negative regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation

negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern

negative regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern

negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation

negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


ciliary receptor clustering involved in hedgehog signaling pathway

ciliary receptor clustering involved in smoothened signalling pathway

ciliary receptor clustering involved in hh signaling pathway

ciliary receptor clustering involved in smoothened signaling pathway

Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway. [GOC:cilia, GOC:dph, GOC:sdb_2009, GOC:tb]


hh signaling pathway involved in dorsal/ventral neural tube patterning

smoothened signalling pathway involved in dorsal/ventral neural tube patterning

hedgehog signaling pathway involved in dorsal/ventral neural tube patterning

smoothened signaling pathway involved in dorsal/ventral neural tube patterning

The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube. [GOC:dph, GOC:sdb_2009, GOC:tb]


oocyte animal/vegetal axis specification

The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus. [GOC:dph, GOC:sdb_2009, GOC:tb]


Wnt receptor signaling pathway involved in animal/vegetal axis specification

Wnt receptor signalling pathway involved in animal/vegetal axis specification

Wnt- activated signaling pathway involved in animal/vegetal axis specification

Wnt signaling pathway involved in animal/vegetal axis specification

The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte. [GOC:dph, GOC:sdb_2009, GOC:tb]


The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo. [GOC:dph, GOC:sdb_2009, GOC:tb]


transforming growth factor receptor beta signalling pathway involved in oral/aboral axis specification

transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification

The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


lymphatic endothelial cell differentiation

The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. [GOC:dph, GOC:sdb_2009, GOC:tb]


blood vessel endothelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. [GOC:dph, GOC:sdb_2009, GOC:tb]


lymphatic endothelial cell fate commitment

The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell. [GOC:dph, GOC:sdb_2009, GOC:tb]


The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell. [GOC:dph, GOC:sdb_2009, GOC:tb]


The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. [GOC:dph, GOC:sdb_2009, GOC:tb]


The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. [GOC:dph, GOC:sdb_2009, GOC:tb]


arterial endothelial cell differentiation

The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins. [GOC:dph, GOC:sdb_2009, GOC:tb]


arterial endothelial cell fate commitment

The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell. [GOC:dph, GOC:sdb_2009, GOC:tb]


The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell. [GOC:dph, GOC:sdb_2009, GOC:tb]


blood vessel endothelial cell fate commitment

The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. [GOC:dph, GOC:sdb_2009, GOC:tb]


A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. [GOC:dph, GOC:sdb_2009, GOC:tb]


vascular endothelial growth factor receptor signalling pathway involved in lymphatic endothelial cell fate commitment

vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment

The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate. [GOC:dph, GOC:sdb_2009, GOC:tb]


Notch signalling pathway involved in arterial endothelial cell fate commitment

Notch signaling pathway involved in arterial endothelial cell fate commitment

The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate. [GOC:dph, GOC:sdb_2009, GOC:tb]


venous endothelial cell migration involved in lymph vessel development

The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells. [GOC:dph, GOC:sdb_2009, GOC:tb]


establishment of BBB
establishment of blood/brain barrier

Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. [GOC:aruk, GOC:dph, GOC:sart, PMID:20080302, PMID:30280653]


establishment of glial blood/brain barrier

establishment of glial blood-brain barrier

Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. [GOC:dph, GOC:sart, PMID:20080302]


membrane trafficking involved in floral organ shedding

vesicle-mediated transport involved in floral organ abscission

The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ. [GOC:dph, GOC:sdb_2009, GOC:tb]


Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs. [GOC:dph, GOC:sdb_2009, GOC:tb]


positive regulation of floral organ abscission

Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs. [GOC:dph, GOC:sdb_2009, GOC:tb]


negative regulation of floral organ abscission

Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs. [GOC:dph, GOC:sdb_2009, GOC:tb]


regulation of floral organ abscission by signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission. [GOC:dph, GOC:sdb_2009, GOC:tb]


negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signalling pathway

negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway

The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission. [GOC:dph, GOC:sdb_2009, GOC:tb]


The controlled shedding of a leaf. [GOC:dph, GOC:sdb_2009, GOC:tb]


The controlled shedding of a fruit. [GOC:dph, GOC:sdb_2009, GOC:tb]


transmembrane receptor protein serine/threonine kinase signalling pathway involved in floral organ abscission

transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission

The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission. [GOC:dph, GOC:sdb_2009, GOC:signaling, GOC:tb]


cell wall disassembly involved in floral organ abscission

A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission. [GOC:dph, GOC:sdb_2009, GOC:tb]


The progression of the semicircular canal from its initial formation to the mature structure. [GOC:dph, GOC:sdb_2009, GOC:tb]


The progession of the anterior semicircular canal from its initial formation to the mature structure. [GOC:dph, GOC:sdb_2009, GOC:tb]


posterior semicircular canal development

The progession of the posterior semicircular canal from its initial formation to the mature structure. [GOC:dph, GOC:sdb_2009, GOC:tb]


The progession of the lateral semicircular canal from its initial formation to the mature structure. [GOC:dph, GOC:sdb_2009, GOC:tb]


The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes. [GOC:dph, GOC:sdb_2009, GOC:tb]


regionalization involved in semicircular canal formation

The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals. [GOC:dph, GOC:sdb_2009, GOC:tb]


pouch outgrowth involved in semicircular canal formation

The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal. [GOC:dph, GOC:sdb_2009, GOC:tb]


Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation. [GOC:dph, GOC:sdb_2009, GOC:tb]


cell morphogenesis involved in semicircular canal fusion

The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion. [GOC:dph, GOC:sdb_2009, GOC:tb]


basal lamina disassembly involved in semicircular canal fusion


regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication


The morphogenetic process in which cells are removed from the inner loop of a semicircular canal. [GOC:dph, GOC:sdb_2009, GOC:tb]


clearance of cells from fusion plate by apoptosis


clearance of cells from fusion plate by epithelial to mesenchymal transition

The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. [GOC:dph, GOC:sdb_2009, GOC:tb]


The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis. [GOC:dph, GOC:sdb_2009, GOC:tb]


limb basal epidermal cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell. [GOC:dph, GOC:sdb_2009, GOC:tb]


limb basal epidermal cell fate specification

The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. [GOC:dph, GOC:sdb_2009, GOC:tb]


retinoic acid receptor signalling pathway involved in spinal cord dorsal/ventral patterning

retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord. [GOC:dph, GOC:sdb_2009, GOC:tb]


The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. [GOC:dph, GOC:sdb_2009, GOC:tb]


The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. [GOC:dph, GOC:sdb_2009, GOC:tb]


eye field cell fate commitment involved in camera-type eye formation

The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode. [GOC:dph, GOC:sdb_2009, GOC:tb]


The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. [GOC:dph, GOC:sdb_2009, GOC:tb]


regulation of hair cycle by canonical Wnt-activated signaling pathway

regulation of hair cycle by canonical Wnt receptor signalling pathway

regulation of hair cycle by canonical Wnt receptor signaling pathway

regulation of hair cycle by Wnt receptor signaling pathway through beta-catenin

regulation of hair cycle by canonical Wnt signaling pathway

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle. [GOC:dph, GOC:sdb_2009, GOC:tb]


regulation of hair cycle by BMP signalling pathway

regulation of hair cycle by BMP signaling pathway

The series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle. [GOC:dph, GOC:sdb_2009, GOC:tb]


Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. [GOC:dph, GOC:tb]


regulation of protein folding in endoplasmic reticulum

Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation). [GOC:dph, GOC:tb]


regulation of induction of conjugation upon nitrogen starvation

Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation. [GOC:dph, GOC:tb]


negative regulation of chromatin silencing by small RNA


positive regulation of macrophage cytokine production

Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:dph, GOC:tb]


The maintenance of the number of copies of extrachromosomal plasmid DNA. [GOC:dph, GOC:tb]


regulation of DNA replication initiation involved in plasmid copy number maintenance

Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance. [GOC:dph, GOC:tb]


negative regulation of DNA replication initiation involved in plasmid copy number maintenance

Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance. [GOC:dph, GOC:tb]


The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system. [GOC:mtg_heart]


The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. [GOC:mtg_heart]


The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. [GOC:mtg_heart]


mesenchymal cell differentiation involved in lung development

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. [GOC:dph]


mesenchymal cell proliferation involved in lung development

The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. [GOC:dph]


regulation of 1,6-beta-glucan biosynthetic process

regulation of (1->6)-beta-D-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans. [GOC:dph, GOC:tb]


The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Auxins are a group of plant hormones that regulates aspects of plant growth. [GOC:dph, GOC:tb]


SAN cell differentiation
SA node cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. [GOC:mtg_heart]


atrioventricular node cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. [GOC:mtg_heart]


cardiomyocyte cell fate commitment
heart muscle cell fate commitment

The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. [GOC:mtg_heart]


atrial cardiomyocyte cell fate commitment

atrial heart muscle cell fate commitment

atrial cardiac muscle cell fate commitment

The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. [GOC:mtg_heart]


ventricular heart muscle cell fate commitment

ventricular cardiomyocyte cell fate commitment

ventricular cardiac muscle cell fate commitment

The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. [GOC:mtg_heart]


The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. [GOC:mtg_heart]


atrioventricular node cell fate commitment

The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells. [GOC:mtg_heart]


SAN cell commitment
SA node cell commitment

The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node. [GOC:mtg_heart]


SAN cell development
SA node cell development

The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. [GOC:mtg_heart]


His-Purkinje system cell differentiation

The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. [GOC:mtg_heart]


The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. [GOC:mtg_heart]


His-Purkinje system cell fate commitment

The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. [GOC:mtg_heart]


The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


epicardium-derived cardiac fibroblast cell differentiation

The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


epicardium-derived cardiac fibroblast cell development

The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


epithelial to mesenchymal transition involved in cardiac fibroblast development

A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast. [GOC:mtg_heart]


epicardium-derived cardiac fibroblast cell fate commitment

The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


neural crest-derived cardiac fibroblast cell differentiation

The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


neural crest-derived cardiac fibroblast cell development

The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


neural crest-derived cardiac fibroblast cell fate commitment

The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:mtg_heart]


The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart. [GOC:mtg_heart]


cardiac blood vessel endothelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels. [GOC:mtg_heart]


heart vascular smooth muscle cell differentiation

cardiac vascular smooth muscle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers. [GOC:mtg_heart]


heart vascular smooth muscle cell development

cardiac vascular smooth muscle cell development

The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state. [GOC:mtg_heart]


heart vascular smooth muscle cell fate commitment

cardiac vascular smooth muscle cell fate commitment

The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell. [GOC:mtg_heart]


The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart. [GOC:mtg_heart]


neural crest-derived cardiac glial cell differentiation

The process in which a neural crest cell acquires the specialized features of a glial cell of the heart. [GOC:mtg_heart]


The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell. [GOC:mtg_heart]


The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells. [GOC:mtg_heart]


neural crest-derived cardiac glial cell development

The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. [GOC:mtg_heart]


neural crest-derived cardiac glial cell fate commitment

The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells. [GOC:mtg_heart]


The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers. [GOC:mtg_heart]


The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. [GOC:mtg_heart]


The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. [GOC:mtg_heart]


The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state. [GOC:mtg_heart]


The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart. [GOC:mtg_heart]


Binds to and stops, prevents or reduces the activity of phospholipase D. [GOC:dph, GOC:tb]


regulation of ribosomal protein gene transcription from RNA polymerase II promoter

regulation of ribosomal protein gene transcription by RNA polymerase II

Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II. [GOC:dph, GOC:tb, GOC:txnOH]


positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter

positive regulation of ribosomal protein gene transcription by RNA polymerase II

Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II. [GOC:dph, GOC:tb, GOC:txnOH]


regulation of gene silencing by microRNA

regulation of miRNA-mediated gene silencing

A process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs). [GOC:aruk, GOC:bc, GOC:dph, GOC:rl, GOC:tb, PMID:23985560, PMID:28379604]


negative regulation of gene silencing by miRNA

negative regulation of gene silencing by microRNA

negative regulation of miRNA-mediated gene silencing

A process that decreases the rate, frequency, or extent of gene silencing by a microRNA (miRNA). [GOC:aruk, GOC:bc, GOC:dph, GOC:rl, GOC:tb, PMID:23985560, PMID:28379604]


Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes. [GOC:dph, GOC:tb]


negative regulation of gene silencing by RNA

Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes. [GOC:dph, GOC:tb]


embryonic heart tube dorsal/ventral pattern formation

The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis. [GOC:mtg_heart]


embryonic heart tube left/right pattern formation

The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place. [GOC:mtg_heart]


The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. [GOC:mtg_heart]


cell migration involved in heart development

The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. [GOC:mtg_heart]


cell migration involved in heart formation

The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. [GOC:mtg_heart]


cardiac progenitor cell midline migration

cardioblast migration to the midline involved in heart field formation

The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. [GOC:mtg_heart]


cardiac vasculature development
coronary blood vessel development
heart vasculature development
heart blood vessel development
cardiac blood vessel development

The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. [GOC:mtg_heart]


heart blood vessel morphogenesis
heart vasculature morphogenesis
cardiac vasculature morphogenesis
coronary blood vessel morphogenesis
cardiac blood vessel morphogenesis

The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. [GOC:mtg_heart]


angiogenesis involved in heart vascular morphogenesis

angiogenesis involved in cardiac vascular morphogenesis

angiogenesis involved in coronary vascular morphogenesis

Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. [GOC:mtg_heart]


vasculogenesis involved in coronary blood vessel morphogenesis

vasculogenesis involved in coronary vascular morphogenesis

The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. [GOC:mtg_heart]


cell migration involved in coronary vasculogenesis

The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. [GOC:mtg_heart]


cell migration involved in coronary angiogenesis

The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. [GOC:mtg_heart]


The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle. [GOC:mtg_heart]


epicardium-derived cardiac vascular smooth muscle cell differentiation

The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers. [GOC:mtg_heart]


epicardium-derived cardiac vascular smooth muscle cell development

The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state. [GOC:mtg_heart]


epicardium-derived cardiac vascular smooth muscle cell fate commitment

The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell. [GOC:mtg_heart]


The regulated release of a hormone into the circulatory system. [GOC:dph]


A macromolecular complex that contains a tube of lipid surrounded by a protein coat. [GOC:ascb_2009, GOC:dph, GOC:tb]


The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission. [GOC:ascb_2009, GOC:dph, GOC:tb]


lipid tubulation involved in organelle fusion

lipid tube assembly involved in organelle fusion

The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse. [GOC:ascb_2009, GOC:dph, GOC:tb]


lipid tubulation involved in organelle fission

lipid tube assembly involved in organelle fission

The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi. [GOC:dph]


Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:dph, GOC:mtg_kidney_jan10]


cell-cell signalling involved in kidney development

cell-cell signaling involved in kidney development

Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ. [GOC:dph, GOC:mtg_kidney_jan10]


The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. [GOC:dph]


The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. [GOC:dph]


regulation of dendritic spine development

Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. [GOC:dph]


positive regulation of dendritic spine development

Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. [GOC:dph]


negative regulation of dendritic spine development

Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. [GOC:dph]


regulation of dendritic spine morphogenesis

Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. [GOC:dph]


negative regulation of dendritic spine morphogenesis

Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. [GOC:dph]


positive regulation of dendritic spine morphogenesis

Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission. [GOC:dph]


pattern formation involved in kidney development

pattern specification involved in kidney development

Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate. [GOC:dph, GOC:mtg_kidney_jan10]


cell differentiation involved in kidney development

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


regulation of cell proliferation involved in kidney morphogenesis

Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney. [GOC:dph, GOC:mtg_kidney_jan10]


An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. [GOC:dph]


The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. [GOC:dph]


The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine. [PMID:20614624]


The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile. [GOC:dph]


The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. [GOC:dph, PMID:20614624]


Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. [GOC:ascb_2009, GOC:dph, GOC:tb]


positive regulation of mRNA catabolic process

Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. [GOC:ascb_2009, GOC:dph, GOC:tb]


The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus. [GOC:ascb_2009, GOC:dph, GOC:tb]


The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body. [GOC:ascb_2009, GOC:dph, GOC:tb]


The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. [GOC:dph, PMID:15226394]


membrane organisation
cellular membrane organization
membrane organization and biogenesis
membrane organization

A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. [GOC:dph, GOC:tb]


The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. [GOC:dph]


The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. [GOC:BHF, GOC:dph]


The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition. [GOC:dph]


The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. [GOC:dph, GOC:yaf]


epithelial cell differentiation involved in mammary gland alveolus development

The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus. [GOC:dph, GOC:yaf]


endodermal digestive tract morphogenesis

The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm. [GOC:dph, GOC:yaf]


The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. [GOC:dph, GOC:yaf]


secretion by lung epithelial cell involved in lung growth

The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development. [GOC:dph]


olfactory bulb mitral cell layer development

The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. [GOC:dph]


Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. [GOC:dph]


positive regulation of cartilage development

Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. [GOC:dph]


negative regulation of cartilage development

Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. [GOC:dph]


The process in which anatomical structures of the uterus are generated and organized. [GOC:BHF, GOC:dph]


Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. [GOC:BHF, GOC:dph]


Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. [GOC:BHF, GOC:dph]


Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. [GOC:dph]


negative regulation of vascular wound healing

Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. [GOC:BHF, GOC:dph]


Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. [GOC:dph]


regulation of branching involved in lung morphogenesis

Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. [GOC:dph, GOC:yaf]


positive regulation of branching involved in lung morphogenesis

Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. [GOC:dph, GOC:yaf]


negative regulation of branching involved in lung morphogenesis

Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. [GOC:dph, GOC:yaf]


cell growth involved in cardiac muscle cell development

The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. [GOC:dph]


regulation of cell growth involved in cardiac muscle cell development

Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. [GOC:dph]


positive regulation of cell growth involved in cardiac muscle cell development

Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. [GOC:dph]


negative regulation of cell growth involved in cardiac muscle cell development

Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. [GOC:dph]


The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. [GOC:dph]


The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. [GOC:dph]


The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. [GOC:dph]


The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. [GOC:dph]


Imd signalling pathway
immune deficiency pathway
Imd signaling pathway
PGRP signaling pathway
immune deficiency signaling pathway

peptidoglycan recognition protein signaling pathway

The series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides. [GOC:dph, PMID:18688280]


regulation of peptidoglycan recognition protein signalling pathway

regulation of peptidoglycan recognition protein signaling pathway

Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. [GOC:dph]


positive regulation of peptidoglycan recognition protein signalling pathway

positive regulation of peptidoglycan recognition protein signaling pathway

Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. [GOC:dph]


negative regulation of peptidoglycan recognition protein signalling pathway

negative regulation of peptidoglycan recognition protein signaling pathway

Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. [GOC:dph]


The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. [GOC:dph]


regulation of nematode larval development

Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. [GOC:dph, GOC:kmv]


positive regulation of nematode larval development

Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. [GOC:dph, GOC:kmv]


negative regulation of nematode larval development

Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. [GOC:dph, GOC:kmv]


Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. [GOC:dph, GOC:kmv]


positive regulation of dauer larval development

Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. [GOC:dph, GOC:kmv]


negative regulation of dauer larval development

Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding. [GOC:dph, GOC:kmv]


The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. [GOC:dph]


The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body. [GOC:dph]


The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening. [GOC:dph]


The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes. [GOC:dph]