regulation of SMAD protein signal transduction

Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of mitotic anaphase-promoting complex activity


negative regulation of anaphase-promoting complex activity during mitotic cell cycle


negative regulation of APC/C activity during mitotic cell cycle


negative regulation of cyclosome activity during mitotic cell cycle


regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process

regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process

Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores. [GOC:dph, GOC:tb]


positive regulation of 1,3-beta-D-glucan biosynthetic process

positive regulation of (1->3)-beta-D-glucan biosynthetic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. [GOC:dph, GOC:tb]


negative regulation of 1,3-beta-D-glucan biosynthetic process

negative regulation of (1->3)-beta-D-glucan biosynthetic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans. [GOC:dph, GOC:tb]


The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone. [GOC:dph, GOC:vw]


positive regulation of prostaglandin secretion involved in immune response

Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response. [GOC:BHF, GOC:dph]


positive regulation of prostaglandin secretion during immune response


The progression of the left horn of the sinus venosus from its initial formation to the mature structure. [GOC:dph]


The progression of the right horn of the sinus venosus from its formation to the mature structure. [GOC:dph]


positive regulation of myeloid leukocyte cytokine production involved in immune response

Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response. [GOC:BHF, GOC:dph]


positive regulation of myeloid cell cytokine production involved in immune response


Any process that contributes to cytokine production by a myeloid cell. [GOC:dph]


Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. [GOC:dph, GOC:tb]


negative regulation of protein refolding

Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. [GOC:BHF, GOC:dph, GOC:tb]


regulation of histone H3-K27 methylation

Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. [GOC:dph, GOC:tb]


negative regulation of histone H3-K27 methylation

Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. [GOC:dph, GOC:tb]


positive regulation of histone H3-K27 methylation

Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone. [GOC:dph, GOC:tb]


Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of sequestering of zinc ion

Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of sequestering of zinc ion

Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system. [GOC:BHF, GOC:dph, GOC:tb]


regulation of phospholipid translocation

Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. [GOC:dph, GOC:jh, GOC:tb, PMID:19966303]


positive regulation of phospholipid translocation

Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. [GOC:dph, GOC:jh, GOC:tb, PMID:19966303]


negative regulation of phospholipid translocation

Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer. [GOC:dph, GOC:jh, GOC:tb, PMID:19966303]


regulation of turning behavior involved in mating

Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. [GOC:dph, GOC:tb]


positive regulation of turning behavior involved in mating

Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. [GOC:dph, GOC:tb]


negative regulation of turning behavior involved in mating

Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. [GOC:dph, GOC:tb]


regulation of protein tyrosine kinase activity

Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity. [GOC:dph, GOC:tb]


positive regulation of protein tyrosine kinase activity

Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity. [GOC:dph, GOC:tb]


negative regulation of protein tyrosine kinase activity

Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity. [GOC:dph, GOC:tb]


lung neuroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium. [GOC:dph, PMID:9126746]


The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. [GOC:dph]


stomach neuroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium. [GOC:dph, PMID:18173746]


gastric neuroendocrine cell differentiation


carotid body glomus cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia. [GOC:dph, PMID:6243386]


The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles. [GOC:dph]


regulation of stomach neuroendocrine cell differentiation

Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. [GOC:dph]


negative regulation of stomach neuroendocrine cell differentiation

Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. [GOC:dph]


The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen. [GOC:dph]


The progression of the seminal vesicle epithelium over time, from its formation to the mature structure. [GOC:dph]


A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells. [GOC:dph]


A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule. [GOC:dph]


epithelial-mesenchymal cell signalling involved in lung development

epithelial-mesenchymal cell signaling involved in lung development

Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ. [GOC:dph]


negative regulation of bud outgrowth involved in lung branching

Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching. [GOC:dph]


Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. [GOC:dph]


branching involved in pancreas morphogenesis

The process in which the branches of the pancreas are generated and organized. [GOC:dph]


The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli. [GOC:dph]


The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth. [GOC:dph]


Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. [GOC:dph, GOC:hjd]


regulation of positive chemotaxis to cAMP

Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. [GOC:dph]


regulation of positive chemotaxis to cAMP by chlorinated alkylphenone

Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. [GOC:dph, PMID:19684855]


regulation of positive chemotaxis to cAMP by DIF-1

Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. [GOC:dph]


regulation of positive chemotaxis to cAMP by DIF-2

Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. [GOC:dph]


positive regulation of positive chemotaxis to cAMP

Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. [GOC:dph]


negative regulation of positive chemotaxis to cAMP

Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP. [GOC:dph]


positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone

Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. [GOC:dph]


negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone

Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions. [GOC:dph]


positive regulation of positive chemotaxis to cAMP by DIF-1

Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. [GOC:dph]


negative regulation of positive chemotaxis to cAMP by DIF-1

Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone. [GOC:dph]


positive regulation of chemotaxis to cAMP by DIF-2

Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. [GOC:dph]


negative regulation of positive chemotaxis to cAMP by DIF-2

Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone. [GOC:dph]


The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. [GOC:dph]


The process in which a specific region of the gut is delineated into the area in which the pancreas will develop. [GOC:dph]


The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas. [GOC:dph]


Binds to and increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. [GOC:dph, GOC:tb]


Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides. [GOC:dph, GOC:tb]


regulation of proteasomal protein catabolic process

Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. [GOC:dph, GOC:tb]


The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch. [GOC:dph]


The process in which the anatomical structures of a branched epithelium are generated and organized. [GOC:dph]


The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. [GOC:dph]


The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part. [GOC:dph]


The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells. [GOC:cilia, GOC:dph, GOC:krc]


mesothelial-mesenchymal cell signalling involved in early lung development

mesothelial-mesenchymal cell signaling involved in early lung development

Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung. [GOC:dph]


The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms. [GOC:dph]


The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule. [GOC:dph]


The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure. [GOC:dph]


The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. [GOC:dph]


The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. [GOC:dph]


extracellular matrix organisation involved in endocardium development

extracellular matrix organization involved in endocardium development

A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. [GOC:dph]


BMP signalling pathway involved in ureter morphogenesis

BMP signaling pathway involved in ureter morphogenesis

The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder. [GOC:dph, GOC:mtg_kidney_jan10]


The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis. [GOC:dph, GOC:yaf]


BMP signalling pathway involved in renal system segmentation

BMP signaling pathway involved in renal system segmentation

The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the segmentation of the renal system. [GOC:dph, GOC:yaf]


The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. [GOC:dph, GOC:yaf]


The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. [GOC:dph]


The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. [GOC:dph, GOC:yaf]


pulmonary artery endothelial tube morphogenesis

The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. [GOC:dph, GOC:yaf]


The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. [GOC:dph, GOC:yaf]


Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. [GOC:dph, GOC:jh]


An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. [GOC:dph, GOC:jh]


establishment of bipolar cell polarity involved in cell morphogenesis

The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane. [GOC:dph, GOC:vw]


regulation of establishment of bipolar cell polarity regulating cell shape

Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell. [GOC:dph, GOC:vw]


positive regulation of establishment of bipolar cell polarity regulating cell shape

Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell. [GOC:dph, GOC:vw]


establishment of monopolar cell polarity

The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. [GOC:dph, GOC:vw]


The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity. [GOC:dph, GOC:vw]


regulation of hair follicle placode formation

Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. [GOC:dph]


positive regulation of hair placode formation

Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. [GOC:dph]


negative regulation of hair follicle placode formation

Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. [GOC:dph]


The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane. [GOC:dph, GOC:vw]


regulation of establishment of bipolar cell polarity

Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane. [GOC:dph, GOC:vw]


positive regulation of establishment of bipolar cell polarity

Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity. [GOC:dph, GOC:vw]


Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. [GOC:dph, GOC:mc]


Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. [GOC:dph, GOC:mc]


Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons. [GOC:dph, GOC:mc]


Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons. [GOC:dph, GOC:mc]


regulation of insulin secretion in response to glucose

regulation of insulin secretion involved in cellular response to glucose stimulus

Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. [GOC:BHF, GOC:dph]


negative regulation of insulin secretion involved in cellular response to glucose stimulus

Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. [GOC:BHF, GOC:dph]


negative regulation of insulin secretion in response to glucose


The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. [GOC:dph, GOC:yaf]


Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. [GOC:BHF, GOC:dph]


negative regulation of chondrocyte development

Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. [GOC:BHF, GOC:dph]


Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. [GOC:BHF, GOC:dph]


positive regulation of dermatome development

Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. [GOC:BHF, GOC:dph]


negative regulation of dermatome development

Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. [GOC:BHF, GOC:dph]


negative regulation of chromatin silencing at silent mating-type cassette

negative regulation of silent mating-type cassette heterochromatin assembly

Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. [GOC:dph, PMID:10388812]


regulation of chromatin silencing at rDNA


negative regulation of chromatin silencing at rDNA


positive regulation of sclerotome development

Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. [GOC:BHF, GOC:dph]


Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. [GOC:dph]


positive regulation of vacuole fusion, non-autophagic

Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. [GOC:dph]


negative regulation of vacuole fusion, non-autophagic

Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole. [GOC:dph]


The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. [GOC:dph]


The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. [GOC:dph]


The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. [GOC:dph]


The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue. [GOC:dph]


The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue. [GOC:dph]


The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue. [GOC:dph]


striated muscle contraction involved in embryonic body morphogenesis

The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology. [GOC:dph, GOC:kmv]


clathrin sculpted GABA transport vesicle

clathrin sculpted gamma-aminobutyric acid transport vesicle

clathrin-sculpted gamma-aminobutyric acid transport vesicle

A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle. [GOC:dph]


clathrin sculpted gamma-aminobutyric acid transport vesicle lumen

clathrin sculpted GABA transport vesicle lumen

clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen

The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle. [GOC:dph]


clathrin sculpted gamma-aminobutyric acid transport vesicle membrane

clathrin sculpted GABA transport vesicle membrane

clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane

The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle. [GOC:dph]


striated muscle paramyosin thick filament assembly

The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle. [GOC:dph, GOC:kmv]


paramyosin filament assembly or disassembly

The formation or disassembly of a filament composed of paramyosin molecules. [GOC:dph, GOC:kmv]


The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin. [GOC:dph, GOC:yaf]


The process in which the anatomical structures of the mesonephros are generated and organized. [GOC:mtg_kidney_jan10]


mesonephric juxtaglomerulus cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


cell differentiation involved in mesonephros development

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


cell proliferation involved in mesonephros development

The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros. [GOC:mtg_kidney_jan10]


cell-cell signalling involved in mesonephros development

cell-cell signaling involved in mesonephros development

Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ. [GOC:mtg_kidney_jan10]


The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. [GOC:mtg_kidney_jan10]


mesonephric juxtaglomerular apparatus development

The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. [GOC:mtg_kidney_jan10]


positive regulation of mesonephros development

Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:mtg_kidney_jan10]


mesonephric smooth muscle tissue development

The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure. [GOC:mtg_kidney_jan10]


The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. [GOC:mtg_kidney_jan10]


Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:mtg_kidney_jan10]


negative regulation of mesonephros development

Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:mtg_kidney_jan10]


The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. [GOC:mtg_kidney_jan10]


The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus. [GOC:mtg_kidney_jan10]


The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric mesenchymal cell proliferation involved in mesonephros development

The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population. [GOC:mtg_kidney_jan10]


mesonephric mesenchymal cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros. [GOC:mtg_kidney_jan10]


mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development

The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa. [GOC:mtg_kidney_jan10]


proximal/distal pattern formation involved in mesonephric nephron development

The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end). [GOC:mtg_kidney_jan10]


pattern specification involved in mesonephros development

Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate. [GOC:mtg_kidney_jan10]


The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric juxtaglomerulus cell development

The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure. [GOC:mtg_kidney_jan10]


mesonephric juxtaglomerulus cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell. [GOC:mtg_kidney_jan10]


mesonephric glomerulus vasculature development

The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. [GOC:mtg_kidney_jan10]


mesonephric glomerular epithelium development

The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric glomerular basement membrane development

The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration. [GOC:mtg_kidney_jan10]


The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros. [GOC:mtg_kidney_jan10]


mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis

The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. [GOC:mtg_kidney_jan10]


mesonephric comma-shaped body morphogenesis

The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. [GOC:mtg_kidney_jan10]


convergent extension involved in mesonephric nephron morphogenesis

The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros. [GOC:mtg_kidney_jan10]


establishment of planar polarity involved in mesonephric nephron morphogenesis

Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros. [GOC:mtg_kidney_jan10]


establishment of planar cell polarity involved in mesonephric nephron morphogenesis


mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. [GOC:mtg_kidney_jan10]


mesonephric nephron tubule morphogenesis

The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric nephron epithelium development

The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros. [GOC:mtg_kidney_jan10]


The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. [GOC:mtg_kidney_jan10]


The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells. [GOC:mtg_kidney_jan10]


The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. [GOC:mtg_kidney_jan10]


establishment or maintenance of bipolar cell polarity

Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns. [GOC:dph, GOC:vw]


establishment or maintenance of bipolar cell polarity regulating cell shape

Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell. [GOC:dph, GOC:vw]


mesonephric glomerular mesangium development

The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. [GOC:mtg_kidney_jan10]


mesonephric glomerulus vasculature morphogenesis

The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. [GOC:mtg_kidney_jan10]


mesonephric glomerular capillary formation

The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. [GOC:mtg_kidney_jan10]


mesonephric glomerular epithelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. [GOC:mtg_kidney_jan10]


mesonephric glomerular epithelial cell development

The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. [GOC:mtg_kidney_jan10]


mesonephric glomerular epithelial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells. [GOC:mtg_kidney_jan10]


mesonephric glomerular parietal epithelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. [GOC:mtg_kidney_jan10]


mesonephric glomerular parietal epithelial cell development

The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. [GOC:mtg_kidney_jan10]


mesonephric glomerular parietal epithelial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes. [GOC:mtg_kidney_jan10]


mesonephric glomerular visceral epithelial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric glomerular visceral epithelial cell development

The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric glomerular visceral epithelial cell fate commitment

mesonephric podocyte cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric glomerular mesangial cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


mesonephric mesangial cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


mesenchymal to epithelial transition involved in mesonephros morphogenesis

A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric mesenchyme to epithelial transition


The developmental process pertaining to the initial formation of the mesonephros. [GOC:mtg_kidney_jan10]


mesonephric glomerular mesangial cell development

The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure. [GOC:mtg_kidney_jan10]


mesonephric glomerular mesangial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell. [GOC:mtg_kidney_jan10]


mesonephric nephron tubule epithelial cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


mesonephros interstitial cell differentiation

mesonephric interstitial fibroblast differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


mesonephros interstitial cell development

mesonephric interstitial fibroblast development

The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure. [GOC:mtg_kidney_jan10]


mesonephric interstitial fibroblast fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast. [GOC:mtg_kidney_jan10]


mesonephric glomerular mesangial cell proliferation involved in mesonephros development

The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population. [GOC:mtg_kidney_jan10]


mesonephric intraglomerular mesangial cell proliferation

The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis. [GOC:mtg_kidney_jan10]


mesenchymal to epithelial transition involved in mesonephric renal vesicle formation

A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle. [GOC:mtg_kidney_jan10]


mesonephric collecting tubule development

mesonephric connecting tubule development

The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. [GOC:mtg_kidney_jan10]


The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. [GOC:mtg_kidney_jan10]


The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule. [GOC:mtg_kidney_jan10]


The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule. [GOC:mtg_kidney_jan10]


mesonephric proximal tubule morphogenesis

The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule. [GOC:mtg_kidney_jan10]


The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros. [GOC:mtg_kidney_jan10]


epithelial cell migration involved in mesonephric nephron tubule morphogenesis

The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis. [GOC:mtg_kidney_jan10]


epithelial cell migration involved in mesonephric distal tubule morphogenesis

The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis. [GOC:mtg_kidney_jan10]


epithelial cell migration involved in mesonephric proximal tubule morphogenesis

The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis. [GOC:mtg_kidney_jan10]


specification of mesonephric collecting tubule identity

specification of mesonephric connecting tubule identity

The process in which the connecting tubule of the mesonephric nephron acquires its identity. [GOC:mtg_kidney_jan10]


specification of mesonephric nephron tubule identity

The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity. [GOC:mtg_kidney_jan10]


specification of mesonephric distal tubule identity

The process in which the distal tubule of the mesonephric nephron acquires its identity. [GOC:mtg_kidney_jan10]


specification of mesonephric proximal tubule identity

The process in which the proximal tubule of the mesonephric nephron acquires its identity. [GOC:mtg_kidney_jan10]


The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. [GOC:mtg_kidney_jan10]


The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. [GOC:mtg_kidney_jan10]


The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. [GOC:mtg_kidney_jan10]


The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. [GOC:mtg_kidney_jan10]


Wnt-activated signaling pathway involved in kidney development

Wnt receptor signaling pathway involved in kidney development

Wnt receptor signalling pathway involved in kidney development

Wnt signaling pathway involved in kidney development

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time. [GOC:mtg_kidney_jan10]


canonical Wnt receptor signalling pathway involved in metanephric kidney development

canonical Wnt-activated signaling pathway involved in metanephric kidney development

canonical Wnt receptor signaling pathway involved in metanephric kidney development

canonical Wnt signaling pathway involved in metanephric kidney development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_kidney_jan10]


canonical Wnt receptor signaling pathway involved in ureteric bud branching

canonical Wnt receptor signalling pathway involved in ureteric bud branching

canonical Wnt signaling pathway involved in ureteric bud branching

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_kidney_jan10]


canonical Wnt-activated signaling pathway involved in mesonephros development

canonical Wnt receptor signalling pathway involved in mesonephros development

canonical Wnt receptor signaling pathway involved in mesonephros development

canonical Wnt signaling pathway involved in mesonephros development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_kidney_jan10]


canonical Wnt receptor signalling pathway involved in mesonephric nephron development

canonical Wnt receptor signaling pathway involved in mesonephric nephron development

canonical Wnt-activated signaling pathway involved in mesonephric nephron development

canonical Wnt signaling pathway involved in mesonephric nephron development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_kidney_jan10]


Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle. [GOC:mtg_kidney_jan10]


regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis

regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis

regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]


negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis

negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis

negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]


positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis

positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis

positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros. [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10]


retina vasculature development in camera-type eye

The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. [GOC:BHF, GOC:dph]


retina vasculature morphogenesis in camera-type eye

The process in which the vasculature of the retina is generated and organized. [GOC:BHF, GOC:dph]


The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. [GOC:dph]


The process in which the vasculature of the cerebellum is generated and organized. [GOC:BHF, GOC:dph]


The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules. [GOC:BHF, GOC:dph, PMID:8837777]


The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. [GOC:dph]


The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. [GOC:BHF, GOC:dph]


maintenance of bipolar cell polarity regulating cell shape

The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell. [GOC:dph, GOC:vw]


cardiac neural crest cell differentiation involved in heart development

The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. [GOC:dph, GOC:mtg_heart, PMID:19705442]


cardiac neural crest cell development involved in heart development

The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. [GOC:dph, GOC:mtg_heart]


cardiac neural crest cell development involved in outflow tract morphogenesis

The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. [GOC:dph, GOC:mtg_heart]


canonical Wnt receptor signalling pathway involved in cardiac neural crest cell differentiation involved in heart development

canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development

canonical Wnt-activated signaling pathway involved in cardiac neural crest cell differentiation involved in heart development

canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation. [GOC:dph, GOC:mtg_heart]


cell surface receptor linked signaling pathway involved in heart development

cell surface receptor linked signalling pathway involved in heart development

cell surface receptor signaling pathway involved in heart development

The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time. [GOC:dph, GOC:mtg_heart, GOC:signaling]


BMP signalling pathway involved in heart development

BMP signaling pathway involved in heart development

The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the progression of the heart over time. [GOC:dph, GOC:mtg_heart]


fibroblast growth factor receptor signalling pathway involved in heart development

fibroblast growth factor receptor signaling pathway involved in heart development

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time. [GOC:mtg_heart]


Notch signalling involved in heart development

Notch signaling involved in heart development

The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time. [GOC:mtg_heart]


canonical Wnt-activated signaling pathway involved in positive regulation of cardiac muscle cell proliferation

canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation

canonical Wnt receptor signalling pathway involved in positive regulation of cardiac muscle cell proliferation

canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation

The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells. [GOC:mtg_heart]


canonical Wnt receptor signalling pathway involved in heart development

canonical Wnt receptor signaling pathway involved in heart development

canonical Wnt-activated signaling pathway involved in heart development

canonical Wnt signaling pathway involved in heart development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_heart]


canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment

canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment

canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment

canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. [GOC:mtg_heart, PMID:17576928]


The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [GOC:dph, GOC:mtg_kidney_jan10]


The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [CL:0002520, GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [CL:0000474, GOC:dph, GOC:mtg_kidney_jan10, GOC:sart, PMID:19783135]


The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [CL:0000486, GOC:dph, GOC:mtg_kidney_jan10, GOC:sart, PMID:19783135]


The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. [CL:0002524, GOC:19783135, GOC:dph, GOC:mtg_kidney_jan10]


cell proliferation involved in heart morphogenesis

The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. [GOC:dph, GOC:mtg_heart]


canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation

canonical Wnt-activated signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation

canonical Wnt receptor signalling pathway involved in positive regulation of cardiac outflow tract cell proliferation

canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation

The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells. [GOC:dph, GOC:mtg_heart]


cell proliferation involved in outflow tract morphogenesis

The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. [GOC:dph, GOC:mtg_heart]


The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. [GOC:dph, GOC:mtg_kidney_jan10]


The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut. [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut. [GOC:dph, GOC:mtg_kidney_jan10]


Malpighian tubule principal cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule. [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


Malpighian tubule stellate cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium. [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


epithelial cell proliferation involved in Malpighian tubule morphogenesis

The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule. [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position. [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. [GOC:dph, GOC:mtg_kidney_jan10]


cell migration involved in Malpighian tubule morphogenesis

cell rearrangement involved in Malpighian tubule morphogenesis

The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule. [GOC:dph, GOC:mtg_kidney_jan10]


cell growth involved in Malpighian tubule morphogenesis

The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule. [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


cell morphogenesis involved in Malpighian tubule morphogenesis

The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule. [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


establishment or maintenance of monopolar cell polarity

Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis. [GOC:dph, GOC:vw]


establishment or maintenance of monopolar cell polarity regulating cell shape

Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell. [GOC:dph, GOC:vw]


non-canonical Wnt receptor signaling pathway involved in heart development

non-canonical Wnt-activated signaling pathway involved in heart development

non-canonical Wnt receptor signalling pathway involved in heart development

non-canonical Wnt signaling pathway involved in heart development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time. [GOC:dph, GOC:mtg_heart, PMID:16860783]


regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signalling pathway

regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway

Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart. [PMID:16860783]


cell adhesion involved in heart morphogenesis

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. [GOC:dph, GOC:mtg_heart, PMID:16860783]


regulation of cell adhesion involved in heart morphogenesis

Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. [GOC:dph, GOC:mtg_heart, PMID:16860783]


planar cell polarity pathway involved in cardiac muscle cell fate commitment

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate. [GOC:dph, GOC:mtg_heart, PMID:16860783]


planar cell polarity pathway involved in heart morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart. [GOC:dph, GOC:mtg_heart, PMID:16860783]


planar cell polarity pathway involved in outflow tract morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract. [GOC:dph, GOC:mtg_heart, PMID:19056682]


planar cell polarity pathway involved in ventricular septum morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum. [GOC:dph, GOC:mtg_heart, PMID:19056682]


planar cell polarity pathway involved in cardiac right atrium morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium. [GOC:dph, GOC:mtg_heart, PMID:19056682]


planar cell polarity pathway involved in cardiac muscle tissue morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue. [GOC:dph, GOC:mtg_heart, PMID:19056682]


The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. [GOC:dph, GOC:yaf]


cell chemotaxis involved in Malpighian tubule morphogenesis

The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule. [GOC:dph, GOC:mtg_kidney_jan10]


bone morphogenic protein receptor signalling pathway involved in Malpighian tubule cell chemotaxis

BMP signaling pathway involved in Malpighian tubule cell chemotaxis

The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule. [GOC:dph, GOC:mtg_kidney_jan10, PMID:19783135]


planar cell polarity pathway involved in pericardium morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium. [GOC:dph, GOC:mtg_heart, PMID:19056682]


The controlled release of a Wnt protein from a cell. [GOC:bf, PMID:19223472]


Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell. [GOC:bf, PMID:19223472]


positive regulation of Wnt protein secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell. [GOC:bf, PMID:19223472]


negative regulation of Wnt protein secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell. [GOC:bf, PMID:19223472]


regulation of Wnt receptor signaling pathway by Wnt protein secretion

regulation of Wnt receptor signalling pathway by Wnt protein secretion

regulation of Wnt-activated signaling pathway by Wnt protein secretion

regulation of Wnt signaling pathway by Wnt protein secretion

Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell. [GOC:bf, GOC:jl, PMID:19223472]


The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature. [GOC:dph]


positive regulation of maintenance of bipolar cell polarity regulating cell shape

Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape. [GOC:dph]


negative regulation of maintenance of bipolar cell polarity regulating cell shape

Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape. [GOC:dph]


negative regulation of progesterone biosynthesis involved in luteolysis

Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis. [GOC:dph]


apoptotic process involved in luteolysis

The apoptotic process that contributes to luteolysis. [GOC:mtg_apoptosis, PMID:18566128]


positive regulation of triglyceride lipase activity

Any process that increases the activity of triglyceride lipase. [GOC:dph]


Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus. [GOC:dph]


behavioral response to acetic acid induced pain

Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus. [GOC:dph]


behavioral response to formalin induced pain

Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus. [GOC:dph]


negative regulation of testicular blood vessel morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle. [GOC:BHF, GOC:dph]


negative regulation of testicular vasculature morphogenesis


The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5. [GOC:dph, GOC:yaf]


determination of cardiac left/right asymmetry

determination of heart left/right asymmetry

Determination of the asymmetric location of the heart with respect to the left and right halves of the organism. [GOC:dph, GOC:mtg_heart]


activin receptor signalling pathway involved in heart jogging

activin receptor signaling pathway involved in heart jogging

The series of molecular signals initiated by the binding of a member of the activin family to its receptor on the surface of a target cell, and contributing to the process of heart jogging. [GOC:dph, GOC:mtg_heart, GOC:signaling]


The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain. [GOC:dph, GOC:yaf, PMID:10662642]


mammillothalamic axonal tract development

The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit. [GOC:dph, GOC:yaf, PMID:10662642]


The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus. [GOC:dph, GOC:yaf, PMID:10662642]


mammillotegmental axonal tract development

The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons. [GOC:dph, GOC:yaf, PMID:10662642]


The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland. [GOC:dph, GOC:yaf]


The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi. [GOC:dph, GOC:yaf]


The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally. [GOC:dph, GOC:yaf]


The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain. [GOC:dph, GOC:yaf]


The orderly movement of a cell that will reside in the diencephalon. [GOC:dph]


Malpighian tubule tip cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells. [GOC:dph, GOC:mtg_kidney_jan10, PMID:7821213]


The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. [GOC:dph]


The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. [GOC:dph]


fibroblast proliferation involved in heart morphogenesis

The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart. [GOC:dph]


The closure of the temporary ventral gap in the optic cup that contributes to its shaping. [GOC:dph]


Binding to a lipoprotein particle receptor. [GOC:BHF, GOC:rl]


inhibition of thiamine diphosphate biosynthetic process


inhibition of thiamine biosynthetic process


mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication

A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication. [GOC:BHF, GOC:mah]


DNA-dependent transcriptional preinitiation complex assembly

DNA-templated transcriptional preinitiation complex assembly

transcription preinitiation complex assembly

The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription. [GOC:jp, GOC:txnOH]


50S ribosomal subunit export from nucleus


60S ribosomal subunit export from nucleus


30S ribosomal subunit export from nucleus


40S ribosomal subunit export from nucleus


Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group. [GOC:jl, GOC:krc, ISBN:0198506732]


cellular response to purine-containing compound

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. [GOC:mah]


mating-type pheromone secretion involved in conjugation with cellular fusion

mating pheromone secretion involved in positive regulation of conjugation with cellular fusion

The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types. [GOC:elh, GOC:jh, GOC:mah]


response to bone morphogenetic protein stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus. [GOC:mah, GOC:yaf]


cellular response to bone morphogenetic protein stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus. [GOC:mah, GOC:yaf]


response to fibroblast growth factor stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus. [GOC:mah]


positive regulation of cell cycle cytokinesis


A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae. These are typically found close to the nucleus and are generally more prominent in secretory cells. [GOC:vw, PMID:16469703, PMID:20434336]


A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section. [GOC:vw, PMID:16469703, PMID:20434336]


endoplasmic reticulum cisternal network organisation

endoplasmic reticulum cisternal network organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. [GOC:vw, PMID:16469703, PMID:20434336]


endoplasmic reticulum cisternal network formation

endoplasmic reticulum cisternal network assembly

The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. [GOC:mah, PMID:16469703, PMID:20434336]


endoplasmic reticulum cisternal network maintenance

The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section. [GOC:mah, PMID:16469703, PMID:20434336]


endoplasmic reticulum tubular network organisation

endoplasmic reticulum tubular network organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section. [GOC:vw, PMID:16469703, PMID:20434336]


endoplasmic reticulum tubular network assembly

endoplasmic reticulum tubular network formation

The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section. [GOC:mah, GOC:vw, PMID:16469703, PMID:20434336]


endoplasmic reticulum tubular network maintenance

The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section. [GOC:mah, PMID:16469703, PMID:20434336]


spindle pole body localization in nuclear envelope

spindle pole body localization to nuclear envelope

spindle pole body localisation in nuclear envelope


Regulated upon Activation, Normal T-cell Expressed, and Secreted binding

Binding to chemokine (C-C motif) ligand 5. [GOC:add, GOC:amm]


The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species. [GOC:dh, PMID:20308541]


bacillithiol biosynthesis
bacillithiol synthesis
bacillithiol anabolism
bacillithiol formation

The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species. [GOC:dh, PMID:20308541]