Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid. [UM-BBD_reactionID:r1074]


Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form). [UM-BBD_reactionID:r1070]


2,4,6-trinitrophenol dihydride denitratase activity

Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP. [UM-BBD_reactionID:r1067]


Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate. [UM-BBD_reactionID:r1069]


branched-chain dodecylbenzene sulfonate monooxygenase activity

Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite. [UM-BBD_reactionID:r1079]


Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate. [UM-BBD_reactionID:r1104]


Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide. [UM-BBD_reactionID:r1119]


Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-. [UM-BBD_reactionID:r1121]


Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol. [UM-BBD_reactionID:r1124]


Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene. [UM-BBD_reactionID:r1131]


Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol. [UM-BBD_reactionID:r1126]


Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2. [UM-BBD_reactionID:r1127]


Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate. [UM-BBD_reactionID:r1128]


Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol. [UM-BBD_reactionID:r1132]


Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate. [UM-BBD_reactionID:r1134]


Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol. [UM-BBD_reactionID:1137]


7,8-dihydroxy benzo(a)pyrene dioxygenase activity

Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate. [UM-BBD_reactionID:r1138]


Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+. [UM-BBD_reactionID:r1135]


Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol. [UM-BBD_reactionID:r1141]


Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-. [UM-BBD_reactionID:r1144]


Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin. [UM-BBD_reactionID:r1149]


Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O. [UM-BBD_reactionID:r1150]


Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+. [UM-BBD_reactionID:r1152]


Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+. [UM-BBD_reactionID:r1155]


Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+. [UM-BBD_reactionID:r1156]


Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi. [UM-BBD_reactionID:r1157]


Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+. [UM-BBD_reactionID:r1159]


tetralin ring-hydroxylating dioxygenase activity

Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+. [UM-BBD_reactionID:r1169]


Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+. [UM-BBD_reactionID:r1170]


1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity

Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+. [UM-BBD_reactionID:r1171]


Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+. [UM-BBD_reactionID:r1172]


Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate. [UM-BBD_reactionID:r1172]


Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate. [UM-BBD_reactionID:r1174]


Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-. [UM-BBD_reactionID:r1176]


Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+. [UM-BBD_reactionID:r1164]


Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-. [UM-BBD_reactionID:r1165]


Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol. [UM-BBD_reactionID:r1177]


Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole. [UM-BBD_reactionID:r1178]


Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole. [UM-BBD_reactionID:r1181]


Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-. [UM-BBD_reactionID:r1179]


Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+. [UM-BBD_reactionID:r1183]


Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone. [UM-BBD_reactionID:r1184]


Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+. [UM-BBD_reactionID:r1185]


Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA. [UM-BBD_reactionID:r1186]


Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi. [UM-BBD_reactionID:r1234]


Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH. [UM-BBD_reactionID:r1238]


Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate. [UM-BBD_reactionID:r1256]


Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-. [UM-BBD_reactionID:r1258]


Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA. [UM-BBD_reactionID:r1259]


Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-. [UM-BBD_reactionID:r1260]


naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity

Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA. [UM-BBD_reactionID:r1261]


Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH. [UM-BBD_reactionID:r1262]


Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol. [UM-BBD_reactionID:r1269]


2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity

Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA. [UM-BBD_reactionID:r1274]


Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-. [UM-BBD_reactionID:r1309]


Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2. [UM-BBD_reactionID:r1278]


Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2. [UM-BBD_reactionID:r1280]


Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O. [UM-BBD_reactionID:r1153]


Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate. [UM-BBD_reactionID:r1281]


Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole. [UM-BBD_reactionID:r1287]


Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole. [UM-BBD_reactionID:r1291]


Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole. [UM-BBD_reactionID:r1292]


Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor. [UM-BBD_reactionID:r1288]


Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-. [UM-BBD_reactionID:r1290]


Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole. [UM-BBD_reactionID:r1294]


Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-. [UM-BBD_reactionID:r1270]


Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-. [UM-BBD_reactionID:r1275]


Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-. [UM-BBD_reactionID:r1271]


Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-. [UM-BBD_reactionID:r1276]


Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA. [UM-BBD_reactionID:r1277]


Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-. [UM-BBD_reactionID:r1273]


Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH. [UM-BBD_reactionID:r1307]


Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one. [UM-BBD_reactionID:r12979]


Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-. [UM-BBD_reactionID:r1308]


Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA. [UM-BBD_reactionID:r1310]


Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O. [UM-BBD_reactionID:r1312]


thioacetamide S-oxide S-oxygenase activity

Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O. [UM-BBD_reactionID:r1313]


Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O. [RHEA:47148]


isonicotinic acid hydrazide hydrolase activity

Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine. [UM-BBD_reactionID:r1336]


Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor. [UM-BBD_reactionID:r1337]


Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor. [UM-BBD_reactionID:r1338]


Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2. [UM-BBD_reactionID:r1340]


Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-. [UM-BBD_reactionID:r1339]


Catalysis of the reaction: citrazinate + H2O = cis-aconitamide. [UM-BBD_reactionID:r1343]


Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3. [UM-BBD_reactionID:r1344]


Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH. [UM-BBD_reactionID:r1350]


Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3. [UM-BBD_reactionID:r1351]


Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O. [UM-BBD_reactionID:r1382]


endosulfan hemisulfate sulfatase activity

Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate. [UM-BBD_reactionID:r1384]


endosulfan diol hydrolyase (cyclizing) activity

Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O. [UM-BBD_reactionID:r1386]


Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-. [UM-BBD_reactionID:r1388]


Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+. [UM-BBD_reactionID:r1389]


Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O. [UM-BBD_reactionID:r1395]


Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+. [UM-BBD_reactionID:r1397]


Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate. [UM-BBD_reactionID:r1398]


Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3. [UM-BBD_reactionID:r1400]


Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol. [UM-BBD_reactionID:r1358]


hexadecyltrimethylammonium chloride monooxygenase activity

Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O. [UM-BBD_reactionID:r1373]


Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O. [EC:1.14.13.148, UM-BBD_reactionID:r1407]


Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate. [UM-BBD_reactionID:r1399]


endosulfan hydroxyether dehydrogenase activity

Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-. [UM-BBD_reactionID:r1411]


Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite. [UM-BBD_reactionID:r1387]


Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O. [UM-BBD_reactionID:r1413]


Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate. [UM-BBD_reactionID:r1436]


Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde. [UM-BBD_reactionID:r1437]


Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine. [UM-BBD_reactionID:r0721]


Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide. [UM-BBD_reactionID:r0723]


Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+. [UM-BBD_reactionID:r0724]


Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine. [UM-BBD_reactionID:r1441]


Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine. [UM-BBD_reactionID:r1442]


Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+. [UM-BBD_reactionID:r1444]


phthalate 3,4-cis-dihydrodiol dehydrogenase activity

Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+. [UM-BBD_reactionID:r1445]


2,4,6-trinitrophenol hydride denitratase activity

Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP. [UM-BBD_reactionID:r1448]


Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA. [UM-BBD_reactionID:r0927]


Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-. [UM-BBD_reactionID:r0928]


Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA. [UM-BBD_reactionID:r0929]


Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-. [UM-BBD_reactionID:r0930]


Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA. [UM-BBD_reactionID:r0931]


Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene. [UM-BBD_reactionID:r0934]


Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-. [UM-BBD_reactionID:r0935]


Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+. [UM-BBD_reactionID:r0936]


Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2. [UM-BBD_reactionID:r0937]


Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2. [UM-BBD_reactionID:r0940]


Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O. [UM-BBD_reactionID:r0941]


Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene. [UM-BBD_reactionID:r0942]


Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O. [UM-BBD_reactionID:r0943]


Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O. [UM-BBD_reactionID:r0946]


Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O. [UM-BBD_reactionID:r0949]


Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX. [UM-BBD_reactionID:r0952]


Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX. [UM-BBD_reactionID:r0953]


Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O. [UM-BBD_reactionID:r0954]


Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX. [UM-BBD_reactionID:r0956]


Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate. [UM-BBD_reactionID:r0939]


Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+. [UM-BBD_reactionID:r0957]


Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+. [UM-BBD_reactionID:r0959]


Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O. [UM-BBD_reactionID:r0980]


Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O. [UM-BBD_reactionID:r0968]


Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate. [UM-BBD_reactionID:r0969]


Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3. [UM-BBD_reactionID:r0984]


Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2. [UM-BBD_reactionID:r0970]


Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi. [UM-BBD_reactionID:r0988]


Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi. [UM-BBD_reactionID:r0989]


Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+. [UM-BBD_reactionID:r0986]


Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA. [UM-BBD_reactionID:r0987]


Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH. [UM-BBD_reactionID:r0994]


Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-. [UM-BBD_reactionID:r0321]


Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate. [UM-BBD_reactionID:r0482]


1,1-dichloroethane reductive dehalogenase activity

Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl. [UM-BBD_reactionID:r1008]


phenylboronic acid monooxygenase activity

Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3. [UM-BBD_reactionID:r1020]


Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate. [UM-BBD_reactionID:r1026]


malonate semialdehyde decarboxylase activity

Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2. [UM-BBD_reactionID:r0266]


Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA. [UM-BBD_reactionID:r1002]


Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether. [UM-BBD_reactionID:r1450]


2,3-dihydroxydiphenyl ether dioxygenase activity

Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol. [UM-BBD_reactionID:r1451]


Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+. [UM-BBD_reactionID:r1453]


Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O. [UM-BBD_reactionID:r1495]


The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin. [GOC:BHF, GOC:rl]


Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA. [GOC:mah]


SET3C
Set3 complex location
HDAC3 complex location
HDAC3 complex

A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p. [GOC:ds, PMID:11711434]


The modification of a histone by addition of one or more methyl groups to a lysine residue. [GOC:mah, GOC:pr]


The modification of a histone by addition of a methyl group to an arginine residue. [GOC:mah]


histone lysine H3 R2 methylation
histone H3R2me
histone H3 R2 methylation

The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone. [GOC:mah]


histone H3R17me
histone lysine H3 R17 methylation
histone H3 R17 methylation

The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone. [GOC:mah]


histone H3 R26 methylation
histone lysine H3 R26 methylation
histone H3R26me

The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone. [GOC:mah]


Sid2-Mob1 complex location
Dbf2p-Mob1p complex location
Sid2-Mob1 kinase complex location
Dbf2p-Mob1p complex
Sid2p-Mob1p complex
Sid2p-Mob1p complex location
Sid2-Mob1 kinase complex

A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex. [GOC:vw, PMID:10837231, PMID:15060149]


A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching. [PMID:14663140]


protein folding in ER
oxidative protein folding

protein folding in endoplasmic reticulum

A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation). [GOC:mah, GOC:vw]


cellular response to endoplasmic reticulum stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. [GOC:cjm, GOC:mah]


ABIN2-NFKB1-TPL-1 complex location
ABIN2-NFKB1-TPL-1 complex
ABIN2-NFKB1-MAP3K8 complex location

A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages. [PMID:15169888]


acinar cell-specific C complex location
PDX1-PBX1b-MRG1 complex location
acinar cell-specific C complex

A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes. [PMID:11279116, PMID:9710595]


NAD-dependent protein deacetylase activity

Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD. [GOC:BHF, GOC:mah, PMID:28450737]


A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation. [PMID:11046156]


A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation. [PMID:11046156]


The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import. [GOC:curators]


The removal of an acetyl group from an acetylated lysine residue in a peptide or protein. [GOC:BHF, GOC:mah]


Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed. [PMID:17344420]


Directly binding to and delivering iron ions to a target protein. [GOC:BHF, GOC:vk]


Binding to one or more specific sites on an immunoglobulin receptor molecule. [GOC:BHF, GOC:vk]


Binding to one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG. [GOC:BHF, GOC:vk]


nuclear mitotic cohesin complex location

A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex. [GOC:mah]


nuclear meiotic cohesin complex location

A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex. [GOC:mah]


LInker of Nucleoskeleton and Cytoskeleton complex location

meiotic nuclear membrane microtubule tethering complex location

A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis. [GOC:mah, PMID:18692466]


microtubule organising centre attachment site organisation

microtubule organizing center attachment site organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches. [GOC:mah, PMID:18692466]


A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly. [PMID:10090939]


A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation. [PMID:1544885]


p21(ras)GAP-Fyn-Lyn-Yes complex location, thrombin stimulated

p21(ras)GAP-Fyn-Lyn-Yes complex, thrombin stimulated


alphav-beta5 integrin-vitronectin complex location

A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin. [PMID:1694173]


oligosaccharyltransferase I complex location

An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes. [PMID:15835887]


oligosaccharyltransferase II complex location

An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes. [GOC:BHF, PMID:15835887]


oligosaccharyltransferase III complex location

An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes. [PMID:15835887]


cilium axoneme assembly
flagellum axoneme assembly
ciliary axoneme assembly
flagellar axoneme assembly

The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194]


Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell. [PMID:10367889, PMID:10675901]


type I protein arginine methyltransferase activity


type II protein arginine methyltransferase activity


pre-microRNA transport from nucleus to cytoplasm

Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product. [GOC:sl, PMID:14744438]


regulation of sporulation resulting in formation of a cellular spore

Any process that modulates the frequency, rate or extent of spore formation. [GOC:jl]


The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis. [GOC:mtg_heart, PMID:9334285]


inhibition of cytokine mediated signaling pathway


activation of cytokine mediated signaling pathway


stimulation of cytokine mediated signaling pathway


ocellus photoreceptor cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus. [GOC:go_curators]


ocellus photoreceptor cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments. [GOC:mtg_sensu]


A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria. [GOC:jl, ISBN:0395825172, PMID:11867431]


plasma membrane-derived chromatophore membrane

The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles. [GOC:jl, GOC:mah, ISBN:0395825172, PMID:11867431]


mitochondrial ATP synthesis coupled electron transport

The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane. [GOC:mtg_sensu, ISBN:0716731363]


laminarinase activity
laminaranase activity


activation of JAK protein by tyrosine phosphorylation

positive regulation of JAK protein activity by tyrosine phosphorylation

The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. [GOC:jl, PMID:12479803]


amino acid activation for nonribosomal peptide biosynthetic process

Activation of an amino acid for incorporation into a peptide by a nonribosomal process. [GOC:jl]


Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells. [GOC:mlg]


Tpg-containing telomere binding complex location

A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species. [PMID:15353591]


Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine. [GOC:jl, PMID:14699121]


regulation of symbiosis, encompassing mutualism through parasitism


isochorismate-pyruvate lyase activity
isochorismate pyruvate lyase activity

Catalysis of the reaction: isochorismate = salicylate + pyruvate. [GOC:jl, PMID:16248620]


Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr). [GOC:jl, PMID:15240874]


Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro). [GOC:jl, PMID:14663147]


Cys-tRNAPro hydrolase activity
Cys-tRNA(Pro) deacetylase activity

Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro). [GOC:jl, PMID:15886196]


Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala). [GOC:jl, PMID:14663147]


Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate. [GOC:jl, PMID:16750290, RHEA:61092]


ATP:coenzyme F420 adenyltransferase activity

ATP:coenzyme F420 adenylyltransferase activity

Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate. [GOC:jl, MetaCyc:RXN-9385, PMID:7957247, PMID:8550473]


Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate. [GOC:jl, PMID:17259313]


Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide. [GOC:jl, PMID:17259313]


Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec). [GOC:jl, PMID:16201757, RHEA:25037]


Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site. [GOC:jl, PMID:16468998]


ribose 1,5-bisphosphate isomerase activity

Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate. [GOC:jl]


cadaverine aminopropyl transferase activity

Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine. [GOC:jl, PMID:17545282]


agmatine aminopropyl transferase activity

Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine. [GOC:jl, PMID:15983049]


Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea. [GOC:jl, PMID:15983049, RHEA:35827]


regulation by host of viral transcription

regulation of viral transcription by host

modulation by host of viral transcription

Any process in which a host organism modulates the frequency, rate or extent of viral transcription. [GOC:jl]


negative regulation of viral transcription by host

negative regulation by host of viral transcription

Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription. [GOC:jl]


positive regulation of viral transcription by host

positive regulation by host of viral transcription

Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA. [GOC:jl]


Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms. [GOC:jl, Wikipedia:Suramin]


exonucleolytic nuclear-transcribed mRNA catabolic process involved in endonucleolytic cleavage-dependent decay

The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap. [GOC:mtg_mpo]


exonucleolytic catabolism of deadenylated mRNA

The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail. [GOC:mtg_mpo]


primary ovarian follicle growth during double layer follicle stage


primary ovarian follicle growth during primary follicle stage


ossification involved in skeletal development

ossification involved in bone maturation

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. [GOC:dph, GOC:mah, GOC:mtg_mpo]


ossification involved in bone remodelling

ossification involved in bone remodeling

The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli. [GO_REF:0000034, GOC:mtg_mpo]


cellular macromolecular complex subunit organisation

cellular macromolecular complex subunit organization

cellular macromolecular complex organization


The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. [GOC:pamgo_curators]


sexual sporulation resulting in formation of a cellular spore

The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. [GOC:pamgo_curators]


asexual reproduction resulting in the formation of a cellular spore

asexual sporulation resulting in formation of a cellular spore

The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. [GOC:pamgo_curators]


Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. [GOC:pamgo_curators]


Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. [GOC:pamgo_curators]


Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. [GOC:pamgo_curators]


regulation of sexual sporulation resulting in formation of a cellular spore

Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. [GOC:pamgo_curators]


positive regulation of sexual sporulation resulting in formation of a cellular spore

Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. [GOC:pamgo_curators]


negative regulation of sexual sporulation resulting in formation of a cellular spore

Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. [GOC:pamgo_curators]


regulation of asexual sporulation resulting in formation of a cellular spore

Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. [GOC:pamgo_curators]


negative regulation of asexual sporulation resulting in formation of a cellular spore

Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. [GOC:pamgo_curators]


positive regulation of asexual sporulation resulting in formation of a cellular spore

Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. [GOC:pamgo_curators]


Any process which modulates the frequency, rate or extent of cAMP-mediated signaling. [GOC:jl]


positive regulation of cAMP-mediated signalling

positive regulation of cAMP-mediated signaling

Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling. [GOC:jl]


negative regulation of cAMP-mediated signalling

negative regulation of cAMP-mediated signaling

Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling. [GOC:jl]


The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide. [GOC:pamgo_curators]


protein translocation by the Sec complex


The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex. [GOC:pamgo_curators]


protein translocation by the TAT complex


protein translocation by the twin-arginine translocation complex


cellular component maintenance at cellular level

The organization process that preserves a cellular component in a stable functional or structural state. [GOC:dph, GOC:jl, GOC:mah]


3-hydroxy propionyl-CoA synthetase activity

Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate. [GOC:jl, PMID:11821399]


acetyl-coenzyme A synthetase/GroES-like domain


AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase

AMP-dependent synthetase and ligase:enoyl-CoA hydratase/isomerase


3-hydroxy propionyl-CoA dehydratase activity

Catalysis of the reaction: 3-hydroxypropionyl-CoA = acrylyl-CoA + H2O. [GOC:jl, PMID:11821399]


acrylyl-CoA reductase (NADPH) activity
acryloyl-CoA reductase (NADPH) activity

Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+. [GOC:jl, PMID:11821399, RHEA:26454]


acrylyl-CoA reductase (NADH)
acryloyl-coenzyme A reductase activity
propionyl-CoA dehydrogenase

Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein. [GOC:jl, PMID:12603323]


Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA. [GOC:jl]


Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O. [GOC:jl]


succinyl-CoA:(R)-citramalate CoA transferase activity

Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA. [GOC:jl, PMID:17259315]


L-carnitine dehydratase/bile acid-inducible protein F


modulation by symbiont of host adenylate cyclase-mediated signal transduction

Any process in which the symbiont modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. [GOC:pamgo_curators]


positive regulation by symbiont of host adenylate cyclase-mediated signal transduction

induction by symbiont of host adenylate cyclase-mediated signal transduction

Any process in which an organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. [GOC:pamgo_curators]


negative regulation by symbiont of host adenylate cyclase-mediated signal transduction

suppression by symbiont of host adenylate cyclase-mediated signal transduction

Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. [GOC:pamgo_curators]


The modification of histone H3 by the addition of an acetyl group. [GOC:jl]


The modification of histone H4 by the addition of an acetyl group. [GOC:jl]


The modification of histone H2A by the addition of an acetyl group. [GOC:jl]


The modification of histone H2B by the addition of an acetyl group. [GOC:jl]


histone H3 acetylation at K9
histone H3K9 acetylation

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone. [GOC:jl]


histone H3K18 acetylation
histone H3 acetylation at K18

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone. [GOC:jl]


histone H3K23 acetylation
histone H3 acetylation at K23

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone. [GOC:jl]


histone H3 acetylation at K4
histone H3K4 acetylation

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone. [GOC:jl]


histone H3K27 acetylation
histone H3 acetylation at K27

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone. [GOC:jl]


histone H3 acetylation at K36
histone H3K36 acetylation

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone. [GOC:jl]


histone H3 acetylation at K79
histone H3K79 acetylation

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 79 of the histone. [GOC:jl]


The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone. [GOC:jl]


The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 9 of the histone. [GOC:jl]


The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone. [GOC:jl]


The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone. [GOC:jl]


The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone. [GOC:jl]


The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone. [GOC:jl]


The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone. [GOC:jl]


The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone. [GOC:jl]


histone H4 R3 methylation
histone H4R3me
histone H4 methylation at R3

The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone. [GOC:mah]


histone H3 phosphorylation at S10
histone H3S10 phosphorylation

The modification of histone H3 by the addition of an phosphate group to a serine residue at position 10 of the histone. [GOC:jl]


histone H3 phosphorylation at S28
histone H3S28 phosphorylation

The modification of histone H3 by the addition of an phosphate group to a serine residue at position 28 of the histone. [GOC:jl]


histone H4 phosphorylation at S1
histone H4S1 phosphorylation

The modification of histone H4 by the addition of an phosphate group to a serine residue at position 1 of the histone. [GOC:jl]


histone H2A phosphorylation at S1
histone H2AS1 phosphorylation

The modification of histone H2A by the addition of an phosphate group to a serine residue at position 1 of the histone. [GOC:jl]


histone H2B phosphorylation at S14
histone H2BS14 phosphorylation

The modification of histone H2B by the addition of an phosphate group to a serine residue at position 14 of the histone. [GOC:jl]


histone lysine N-acetyltransferase activity (H3-K9 specific)

histone acetyltransferase activity (H3-K9 specific)

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H3-K18 specific)

histone acetyltransferase activity (H3-K18 specific)

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H3-K23 specific)

histone acetyltransferase activity (H3-K23 specific)

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H4-K5 specific)

histone acetyltransferase activity (H4-K5 specific)

Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H4-K8 specific)

histone acetyltransferase activity (H4-K8 specific)

Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H4-K12 specific)

histone acetyltransferase activity (H4-K12 specific)

Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12). [EC:2.3.1.48]


H2A histone lysine N-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine. [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H2A-K5 specific)

histone acetyltransferase activity (H2A-K5 specific)

Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H2A-K9 specific)

histone acetyltransferase activity (H2A-K9 specific)

Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9). [EC:2.3.1.48]


H2B histone lysine N-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine. [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H2B-K5 specific)

histone acetyltransferase activity (H2B-K5 specific)

Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H2B-K12 specific)

histone acetyltransferase activity (H2B-K12 specific)

Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H3-K4 specific)

histone acetyltransferase activity (H3-K4 specific)

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H3-K27 specific)

histone acetyltransferase activity (H3-K27 specific)

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H3-K36 specific)

histone acetyltransferase activity (H3-K36 specific)

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36). [EC:2.3.1.48]


histone lysine N-acetyltransferase activity (H3-K72 specific)

histone acetyltransferase activity (H3-K72 specific)

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72). [EC:2.3.1.48]


histone-arginine N-methyltransferase activity (H4-R3 specific)

histone methylase activity (H4-R3 specific)

histone methyltransferase activity (H4-R3 specific)

Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4. [GOC:mah, PMID:17898714]


histone serine kinase activity (H3-S28 specific)

histone-serine kinase activity (H3-S28 specific)

histone kinase activity (H3-S28 specific)

Catalysis of the transfer of a phosphate group to the serine-28 residue of the N-terminal tail of histone H3. [GOC:jl]


histone-serine kinase activity (H4-S1 specific)

histone serine kinase activity (H4-S1 specific)

histone kinase activity (H4-S1 specific)

Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H4. [GOC:jl]


histone-serine kinase activity (H2A-S1 specific)

histone serine kinase activity (H2A-S1 specific)

histone kinase activity (H2A-S1 specific)

Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H2A. [GOC:jl]


histone-serine kinase activity (H2B-S14 specific)

histone serine kinase activity (H2B-S14 specific)

histone kinase activity (H2B-S14 specific)

Catalysis of the transfer of a phosphate group to the serine-14 or an equivalent residue of the N-terminal tail of histone H2B. [GOC:jl]


An increase in the epigenetic methylation of cytosine and adenosine residues in DNA. [GOC:jl, http://en.wiktionary.org/]


An increase in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes. [GOC:jl, Wikipedia:Cpg_island]


An decrease in the epigenetic methylation of cytosine and adenosine residues in DNA. [GOC:jl, http://en.wiktionary.org/hypomethylation]


An decrease in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes. [GOC:jl, Wikipedia:Cpg_island]


modulation by symbiont of IAA levels in host

modulation by symbiont of indole acetic acid levels in host

The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. [GOC:pamgo_curators]


modulation by symbiont of auxin levels in host


The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues. [GOC:jl]


transport of peptides or proteins into host cell cytoplasm

translocation of symbiont peptides or proteins into host cell cytoplasm

translocation of peptides or proteins into host cell cytoplasm

The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm. [MITRE:tk]


modulation by symbiont of host system process

The process in which a symbiont organism effects a change in an anatomical system process of its host organism. [GOC:pg]


regulation by symbiont of host digestive system process

modulation by symbiont of host digestive system process

The alteration by a symbiont organism of the functioning of a digestive system process, a physical, chemical, or biochemical process carried out by the host organism to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. [MITRE:tk]


Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. [GOC:jl]


Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. [GOC:jl]


regulation by symbiont of host endocrine process

modulation by symbiont of host endocrine process

The alteration by a symbiont organism of the functioning of a endocrine process, any of the hormonal, neural, and secretory processes that release products into the blood or lymph, in the host organism. [MITRE:tk]


Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. [GOC:jl]


Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. [GOC:jl]


regulation by symbiont of host neurological system process

modulation by symbiont of host neurological system process

modulation by symbiont of host nervous system process

The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system. [MITRE:tk]


regulation by symbiont of host respiratory system process

modulation by symbiont of host respiratory system process

The alteration by a symbiont organism of the functioning of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. [MITRE:tk]


regulation of respiratory system process

Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. [GOC:jl]


modification by symbiont of host nucleus

modification of host cell nucleus by symbiont

modification of host nucleus by symbiont

modification by symbiont of host cell nucleus

The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus. [MITRE:tk]


modification of host intercellular junctions by symbiont

modification by symbiont of host intercellular junctions

The process in which a symbiont organism effects a change in the structure or function of its host intercellular junction, a specialized region of connection between two cells. [MITRE:tk]


regulation by symbiont of host cellular process

regulation of host cellular process by symbiont

modulation of host cellular process by symbiont

modulation by symbiont of host cellular process

Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism. [MITRE:tk]


modification of host anion transport by symbiont

modulation by symbiont of host anion transport

The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism. [MITRE:tk]


Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


modification by symbiont of host cell cycle

regulation by symbiont of host cell cycle

modulation of host cell cycle by symbiont

modulation by symbiont of host cell cycle

The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery. [MITRE:tk]


negative regulation by symbiont of host cell cycle

The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery. [MITRE:tk]


modification by symbiont of host translation

regulation by symbiont of host translation

modulation of host translation by symbiont

modulation by symbiont of host translation

The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism. [MITRE:tk]


negative regulation of host translation by symbiont

negative regulation by symbiont of host translation

The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism. [MITRE:tk]


modulation by symbiont of host vacuole biogenesis


positive regulation by symbiont of host vacuole biogenesis


modulation of host receptor-mediated endocytosis by symbiont

regulation by symbiont of host receptor-mediated endocytosis

modulation by symbiont of host receptor-mediated endocytosis

The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism. [MITRE:tk]


positive regulation of host receptor-mediated endocytosis by symbiont

positive regulation by symbiont of host receptor-mediated endocytosis

Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism. [MITRE:tk]


regulation by symbiont of host neurotransmitter secretion

modulation of host neurotransmitter secretion by symbiont

modification by symbiont of host neurotransmitter secretion

modulation by symbiont of host neurotransmitter secretion

Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism. [MITRE:tk]


modulation of host cGMP-mediated signal transduction by symbiont

regulation by symbiont of host cGMP-mediated signal transduction

modulation by symbiont of host cGMP-mediated signalling

modulation by symbiont of host cGMP-mediated signaling

modulation by symbiont of host cGMP-mediated signal transduction pathway

Any process in which a symbiont organism modulates the rate, frequency or extent of cGMP-mediated signaling in its host organism. [MITRE:tk]


modulation of host nitric oxide-mediated signal transduction by symbiont

modulation of host nitric oxide-mediated signalling by symbiont

modulation by symbiont of host nitric oxide mediated signal transduction

regulation by symbiont of host nitric oxide-mediated signal transduction

modulation of host nitric oxide-mediated signaling by symbiont

modulation by symbiont of host nitric oxide-mediated signal transduction

Any process in which a symbiont organism modulates the rate, frequency or extent of nitric oxide mediated signal transduction in its host organism. [MITRE:tk]


regulation by symbiont of host small GTPase mediated signal transduction

modulation of host small GTPase mediated signal transduction by symbiont

modulation by symbiont of host small GTPase mediated signal transduction

Any process in which a symbiont organism modulates the frequency, rate or extent of small GTPase mediated signal transduction in its host organism. [MITRE:tk]


regulation by symbiont of host Rho protein signal transduction

modulation of host Rho protein signalling by symbiont

modulation by symbiont of host Rho protein mediated signal transduction

modulation of host Rho protein signaling by symbiont

modulation of host Rho protein signal transduction by symbiont

modulation by symbiont of host Rho protein-mediated signal transduction

modulation by symbiont of host Rho protein signal transduction

Any process in which a symbiont organism modulates the frequency, rate or extent of Rho protein signal transduction in its host organism. [MITRE:tk]


host cell membrane pore complex location

pore complex location in host cell membrane

Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins. [MITRE:tk]


regulation of cellular component biogenesis

Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. [GOC:jl]


regulation of vacuole biogenesis
regulation of vacuole organisation

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. [GOC:jl, GOC:mah]


positive regulation of cellular component biogenesis

Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. [GOC:jl]


positive regulation of vacuole organisation

positive regulation of vacuole biogenesis

positive regulation of vacuole organization

Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. [GOC:jl, GOC:mah]


maintenance of protein location in Golgi apparatus


The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis. [GOC:vw, PMID:10690419]


Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away. [GOC:bf]


establishment or maintenance of epithelial cell apical/basal polarity

Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell. [GOC:bf, GOC:mah]


establishment of epithelial cell apical/basal polarity

The specification and formation of the apicobasal polarity of an epithelial cell. [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb]


maintenance of epithelial cell apical/basal polarity

The maintenance of the apicobasal polarity of an epithelial cell. [GOC:bf]


microtubule organising centre attachment site

microtubule organizing center attachment site

A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope. [GOC:mah, PMID:18692466]


hydrogen ion transporting ATP synthase activity, rotational mechanism

hydrogen ion transporting two-sector ATPase activity

hydrogen ion translocating F-type ATPase activity

Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out). [RHEA:57720]

proton-transporting ATP synthase activity, rotational mechanism


2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase activity

Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase. [EC:2.7.7.61, MetaCyc:2.7.7.61-RXN]


inhibition of striated muscle cell apoptosis


A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place. [GOC:ds, GOC:mah]


A glass-like, pale intracellular inclusion. [NIF_Subcellular:nlx_subcell_20090104]


The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet. [GOC:dph, PMID:16962574, PMID:18343170]


A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located. [PMID:11526084]


coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity

NAD(P)H elemental sulfur oxidoreductase activity

Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+. [GOC:jl, PMID:17449625]

CoA-dependent NAD(P)H sulfur oxidoreductase activity


activated T lymphocyte autonomous cell death

activated T-lymphocyte autonomous cell death

A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


Membrane-bound prokaryotic organelles of magnetotactic bacteria that contain chains of MAGNETITE crystals which orient the bacteria to geomagnetic fields.


protein serine-threonine kinase activity

serine(threonine) protein kinase activity

serine/threonine protein kinase activity

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. [GOC:bf, PMID:2956925]

protein serine/threonine kinase activity


contractile ring localization involved in cell cycle cytokinesis

contractile ring localisation involved in cell cycle cytokinesis

actomyosin contractile ring localization

The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle. [GOC:mah]


establishment of contractile ring localization involved in cell cycle cytokinesis

establishment of contractile ring localization involved in cytokinesis during cell cycle

cytokinesis site selection by contractile ring positioning

establishment of contractile ring localisation involved in cell cycle cytokinesis

establishment of actomyosin contractile ring localization

The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis. [GOC:mah]


maintenance of contractile ring localisation involved in cell cycle cytokinesis

maintenance of contractile ring localization involved in cell cycle cytokinesis

maintenance of contractile ring localization involved in cytokinesis during cell cycle

maintenance of actomyosin contractile ring localization

Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere. [GOC:mah]


cell wall macromolecule catabolic process during cytogamy


regulation of actin filament bundle assembly

Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. [GOC:mah]


endoplasmic reticulum-dependent peroxisome organization

A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum. [GOC:mah, PMID:16717127, PMID:17646399]


neuron cell body membrane
neuronal cell soma membrane

The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites. [GOC:jl]


Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol. [GOC:mlg, PMID:12540833]


ATPase-coupled oligogalacturonide transmembrane transporter activity

ATP-dependent oligogalacturonide transmembrane transporter activity

oligogalacturonide transporting ATPase activity

ABC-type oligogalacturonide transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in). [GOC:mlg, PMID:11555291, PMID:17451747]


dopamine neurotransmitter receptor activity, coupled via Gs

Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity. [GOC:mah, ISBN:0953351033, IUPHAR_RECEPTOR:2252, IUPHAR_RECEPTOR:2260]


dopamine neurotransmitter receptor activity, coupled via Gi/Go

Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity. [GOC:mah, ISBN:0953351033, IUPHAR_RECEPTOR:2254, IUPHAR_RECEPTOR:2256, IUPHAR_RECEPTOR:2258]


D,D-heptose 1,7-bisphosphate phosphatase activity

Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate. [MetaCyc:RXN0-4361, PMID:11279237]


Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O. [MetaCyc:RXN-8848]


anterior/posterior pattern specification involved in pronephric kidney development

anterior/posterior pattern specification involved in pronephros development

The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. [GOC:mah]


Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3. [UM-BBD_reactionID:r1497]


The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division. [GOC:bf, PMID:11735001]


Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. [GOC:bf]


An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues. [PMID:12435357, PMID:7925006]


A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins. [PMID:10556087, PMID:7925006, PMID:9093858]


G-protein coupled glutamate receptor binding

G protein-coupled glutamate receptor binding

Binding to a G protein-coupled glutamate receptor (a metabotropic glutamate receptor). [GOC:bf, ISBN:0198506732, PMID:9069287]


inhibition of translation involved in gene silencing by miRNA


mesenchymal cell migration involved in limb bud formation

The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud. [GOC:dgh]


An intercellular bridge that connects the germline cells of a male cyst. [PMID:9635420]


An intercellular bridge that connects the germline cells of a female cyst. [PMID:9635420]


Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. [PMID:19076341]


regulation of hippo signaling pathway
regulation of hippo signalling cascade
regulation of hippo signaling cascade

Any process that modulates the frequency, rate or extent of hippo signaling. [GOC:bf]


negative regulation of hippo signaling cascade

negative regulation of hippo signalling cascade

negative regulation of hippo signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling. [GOC:bf]


positive regulation of hippo signalling cascade

positive regulation of hippo signaling pathway

positive regulation of hippo signaling cascade

Any process that activates or increases the frequency, rate or extent of hippo signaling. [GOC:bf]


Notch receptor processing, ligand-dependent

The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD). [GOC:bf, PMID:12651094]


Notch receptor processing, ligand-independent

The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface. [GOC:bf, PMID:12651094]


The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine. [GOC:bf]


long-chain fatty acyl CoA metabolic process

long-chain fatty-acyl-CoA metabolic process

The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. [ISBN:0198506732]


fatty acyl CoA metabolic process
fatty-acyl-CoA metabolism

The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. [ISBN:0198506732]


long-chain fatty acyl CoA biosynthetic process

long-chain fatty-acyl-CoA biosynthetic process

The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more. [ISBN:0198506732]


serine palmitoyltransferase, Orm1/2, Tsc3 and Sac1 complex location

A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis. [PMID:20182505]


The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [PMID:19135251]


regulation of hypoxanthine riboside transport

Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf]


positive regulation of hypoxanthine riboside transport

positive regulation of inosine transport

Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf]


negative regulation of hypoxanthine riboside transport

negative regulation of inosine transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf]


6-hydroxypurine transport
hypoxanthine transmembrane transport

The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:sl]


Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf]


positive regulation of 6-hydroxypurine transport

positive regulation of hypoxanthine transport

Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf]


negative regulation of 6-hydroxypurine transport

negative regulation of hypoxanthine transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf]


The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. [GO:bf]


The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. [GOC:bf]


The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form. [GOC:bf, ISBN:0198506732]


The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:bf]


The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH. [GOC:bf]


nicotinamide mononucleotide membrane transport

nicotinamide mononucleotide transmembrane transport

The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP. [GOC:bf, ISBN:0721662544]


Toll-like receptor 1-Toll-like receptor 2 protein complex location

toll-like receptor TLR1:TLR2 heterodimeric complex location

A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2). [GOC:add, GOC:signaling, PMID:17889651, PMID:21481769]


Toll-like receptor 2-Toll-like receptor 6 protein complex location

toll-like receptor TLR6:TLR2 heterodimeric complex location

A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6). [GOC:add, GOC:signaling, PMID:19931471, PMID:21481769]


Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment. [GOC:BHF]


peroxisome proliferator activated receptor signalling pathway

peroxisome proliferator activated receptor signaling pathway

The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes. [GOC:BHF, PMID:18221086]

peroxisome proliferator-activated receptor signaling pathway


regulation of peroxisome proliferator-activated receptor signaling pathway

regulation of peroxisome proliferator activated receptor signalling pathway

regulation of peroxisome proliferator activated receptor signaling pathway

Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. [GOC:bf]


negative regulation of PPAR signaling pathway

negative regulation of peroxisome proliferator-activated receptor signaling pathway

negative regulation of peroxisome proliferator activated receptor signalling pathway

negative regulation of peroxisome proliferator activated receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. [GOC:bf]


positive regulation of peroxisome proliferator activated receptor signalling pathway

positive regulation of peroxisome proliferator-activated receptor signaling pathway

positive regulation of PPAR signaling pathway

positive regulation of peroxisome proliferator activated receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. [GOC:bf]


Cul8-RING ubiquitin ligase complex location

A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins. [GOC:krc, PMID:20139071]


protein-DNA interferon-stimulated response element complex assembly

The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA. [GOC:amm, PMID:11747630]


A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body. [GOC:sart, PMID:16533947, PMID:18927579, PMID:19620235]


thymine transmembrane transport
5-methyluracil transport

The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GO:sl]


Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf, GOC:sl]


negative regulation of 5-methyluracil transport

negative regulation of thymine transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf, GOC:sl]


positive regulation of 5-methyluracil transport

positive regulation of thymine transport

Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:bf, GOC:sl]


selenocysteine insertion sequence binding

Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation. [GOC:imk, PMID:10760958]


pre-B cell receptor complex location
pre-BCR

An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. [GOC:add, ISBN:0781765196, PMID:16464608, PMID:17306522]


A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A). [GOC:amm, PMID:16129784]


A process in which a protein is transported to, or maintained at, a microtubule. [GOC:bf, GOC:lb]


chondroitin sulfate proteoglycan binding

Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit. [GOC:kmv, ISBN:0198506732]


Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). [GOC:kmv, ISBN:0198506732]


Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis. [ISBN:0198506732]


The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [GOC:bf, PMID:19793923]


The directed movement of water (H2O) from one side of an epithelium to the other. [GOC:yaf]


The process in which carbon dioxide (CO2) is transported across a membrane. [GOC:yaf]


carbon dioxide transmembrane transporter activity

Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other. [GOC:yaf]


very long-chain-3-hydroxyacyl-CoA dehydrogenase activity

Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22. [GOC:pde]


Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts. [GOC:bf]


The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [GOC:vw]


The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol. [GOC:bf, Wikipedia:Thioester]


thioester formation
thioester anabolism
thioester biosynthesis
thioester synthesis

The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol. [GOC:bf, http://encyclopedia.thefreedictionary.com/Thioester]


Roundabout signalling pathway
ROBO signaling pathway
ROBO/SLIT signaling pathway

The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:signaling]


regulation of Roundabout signalling pathway

regulation of Roundabout signaling pathway

Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway. [GOC:BHF]


negative regulation of Roundabout signalling pathway

negative regulation of Roundabout signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway. [GOC:BHF]


positive regulation of Roundabout signalling pathway

positive regulation of Roundabout signaling pathway

Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway. [GOC:BHF]


establishment of chromatin silencing at silent mating-type cassette


Monokine induced by gamma interferon production

chemokine (C-X-C motif) ligand 9 production

The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add]


regulation of MIG production
regulation of CXCL9 production

regulation of chemokine (C-X-C motif) ligand 9 production

Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. [GOC:bf]


negative regulation of CXCL9 production
negative regulation of MIG production

negative regulation of chemokine (C-X-C motif) ligand 9 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. [GOC:bf]


positive regulation of CXCL9 production
positive regulation of MIG production

positive regulation of chemokine (C-X-C motif) ligand 9 production

Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9. [GOC:bf]


helper T cell enhancement of adaptive immune response

Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell. [GOC:add]


helper T cell enhancement of T cell mediated immunity

helper T cell enhancement of T cell mediated immune response

Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell. [GOC:add]


helper T cell enhancement of B cell mediated immunity

helper T cell enhancement of B cell mediated immune response

Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell. [GOC:add]


Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. [GOC:bf]


histone tyrosine kinase activity (H3-Y41 specific)

histone-tyrosine kinase activity (H3-Y41 specific)

histone kinase activity (H3-Y41 specific)

Catalysis of the transfer of a phosphate group to the tyrosine-41 residue of histone H3. [GOC:bf]


histone threonine kinase activity (H3-T11 specific)

histone-threonine kinase activity (H3-T11 specific)

histone kinase activity (H3-T11 specific)

Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3. [GOC:bf]


histone threonine kinase activity (H3-T6 specific)

histone-threonine kinase activity (H3-T6 specific)

histone kinase activity (H3-T6 specific)

Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3. [GOC:bf]


The modification of histones by addition of a phosphate group to a serine residue. [GOC:bf]


The modification of histones by addition of a phosphate group to a threonine residue. [GOC:bf]


The modification of histones by addition of a phosphate group to a tyrosine residue. [GOC:bf]


The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone. [GOC:bf]


The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone. [GOC:bf]


The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone. [GOC:bf]


Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH. [GOC:ecd, http://www.brenda-enzymes.org/php/result_flat.php4?ecno=1.1.1.63, PMID:4152755]


Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. [GOC:bf]


extracellular matrix-cell signalling
cell-extracellular matrix signalling

Any process that mediates the transfer of information between the extracellular matrix and a cell. [GOC:bf]


upregulation of vulval development
up-regulation of vulval development


nuclear membrane-endoplasmic reticulum continuum

nuclear outer membrane-endoplasmic reticulum membrane network

The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. [GOC:bf, GOC:jl, GOC:mah, GOC:mcc, GOC:pr, GOC:vw]


establishment of planar polarity of follicular epithelium

Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates. [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb]


establishment of planar polarity of embryonic epithelium

Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates. [GOC:ascb_2009, GOC:dph, GOC:jl, GOC:tb]


establishment of planar polarity of larval imaginal disc epithelium

Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates. [GOC:jl]


cuticle biosynthetic process during molting


perception of triacylated bacterial lipopeptide


Binding to a lipopeptide containing a nonprotein moiety consisting of three acyl groups. [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794]


perception of diacylated bacterial lipopeptide


NADH dehydrogenase (ubiquinone) complex location, peripheral segment

NADH dehydrogenase (ubiquinone) complex, peripheral segment


NADH-Q oxidoreductase complex location, peripheral segment

NADH-Q oxidoreductase complex, peripheral segment


NADH-Q oxidoreductase complex location, membrane segment

NADH-Q oxidoreductase complex, membrane segment


The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells. [GOC:mah]


cell wall synthesis
cell wall anabolism
cell wall biosynthetic process
cell wall formation


Gram-negative-bacterium-type cell outer membrane assembly

The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures. [GOC:jl, ISBN:0135712254]


The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. [GOC:ef, GOC:mtg_muscle, PMID:12021255, PMID:16607119]


The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. [GOC:go_curators]


The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. [GOC:jl]


The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. [GOC:go_curators]


regulation of skeletal muscle tissue regeneration

Any process that modulates the frequency, rate or extent of skeletal muscle. [GOC:jl]


histone chaperone
histone chaperone activity

Binding to and carrying a histone or a histone complex to unload or deposit it as a nucleosome. The histone can be newly synthesized or result from nucleosome disassembly (either spontaneously, or by a histone chaperone). [PMID:26459557]