Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA. [PMID:10521354, PMID:16751265]


The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates. [ISBN:0198506732]


The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine. [RESID:AA0062]


The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline. [RESID:AA0066]


The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine. [RESID:AA0074]


The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine. [RESID:AA0076]


The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine. [RESID:AA0075]


Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate. [RHEA:42568]


1,1,1-trichloroethane reductive dehalogenase activity

Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl. [UM-BBD_reactionID:r1007]


nucleoside diphosphate-sugar hydrolase activity


aerobic ammonia oxidation to nitrite via hydrazine

aerobic respiration, using ammonia as electron donor

The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite. [MetaCyc:AMMOXID-PWY]


L-alanine oxidation to D-lactate and ammonia

The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia. [MetaCyc:ALACAT2-PWY]


The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine. [RESID:AA0061]


Atg12 conjugating enzyme activity
APG12 conjugating enzyme activity

Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue. [GOC:dph]


negative regulation of cell shape and cell size


positive regulation of cell shape and cell size


Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. [GOC:mah, ISBN:0815316194]


A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. [PMID:10567516]


A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit. [PMID:10567516]


centromere complex
chromosome, centric region
centromere complex location

The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. [GOC:cjm, GOC:elh, GOC:kmv, GOC:pr]


condensed chromosome, centromeric region

The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. [GOC:elh, GOC:kmv]


cell morphogenesis involved in differentiation

The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. [GOC:go_curators]


imperfect stage fruiting body development


The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation. [GOC:clt, GOC:mah]


The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast. [GOC:clt]


nuclear mRNA degradation
nuclear mRNA breakdown
nuclear mRNA catabolism

nuclear-transcribed mRNA catabolic process

The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells. [GOC:krc]


The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. [GOC:krc, GOC:mah]


The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion. [GOC:krc, GOC:mah]


The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. [GOC:krc, GOC:mah]


regulation of mitochondrial RNA catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. [GOC:krc, GOC:mah]


negative regulation of mitochondrial RNA catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. [GOC:krc, GOC:mah]


positive regulation of mitochondrial RNA catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. [GOC:krc, GOC:mah]


The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion. [GOC:krc, GOC:mah]


Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion. [GOC:krc, GOC:mah]


Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion. [GOC:krc, GOC:mah]


Any process involved in forming the mature 5' end of an RNA molecule. [GOC:krc]


Any process involved in forming the mature 5' end of an rRNA molecule. [GOC:krc]


The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. [GOC:mah]


endoplasmic reticulum unfolded protein response

The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. [GOC:mah, PMID:12042763]


deadenylation-independent decapping of nuclear mRNA


positive regulation of microtubule catastrophe


The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules. [GOC:pg, PMID:14706699]


The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi. [GOC:mah, PMID:14734532]


regulation of mating projection assembly

Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi. [PMID:14734532]


cell envelope Sec protein transport complex location

A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC. [GOC:mtg_sensu, PMID:15223057]


Any process that initiates the activity of inactive phospholipase D. [GOC:dph, GOC:mah, GOC:tb]


microtubule basal body organization and biogenesis

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum). [GOC:cilia, GOC:dph, GOC:jl, GOC:krc, GOC:mah, PMID:9889124]


plasma membrane blebbing
plasma membrane bleb assembly
cell blebbing

The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)]


maintenance of secretory granule location

Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere. [GOC:dph, GOC:mah, GOC:tb]


maintenance of dense core vesicle location

maintenance of dense core granule location

Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere. [GOC:dph, GOC:mah, GOC:tb]


The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. [GOC:dgh, GOC:dph, GOC:tb]


Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. [GOC:isa_complete, GOC:mah]


maintenance of protein localization in cell


A process that modulates the formation of a microvillus. [GOC:mah]


A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins. [GOC:pamgo_curators]


Twin-arginine translocation complex location


heptose 1-phosphate adenyltransferase activity

D-beta-D-heptose 1-phosphate adenylyltransferase activity

Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose. [MetaCyc:RXN0-4342]


Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin. [RHEA:25629]


heparin-glucosamine 3-sulfotransferase 2 activity


heparin-glucosamine 3-sulfotransferase 3 activity


pituitary adenylate cyclase-activating peptide receptor activity


de novo NAD biosynthetic process from tryptophan

'de novo' NAD biosynthetic process from tryptophan

The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. [PMID:17161604]


A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph. [GOC:BHF, GOC:expert_pt, GOC:rl]


A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


very-low-density lipoprotein complex location

A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


low-density lipoprotein complex location

A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


intermediate-density lipoprotein complex location

A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL). [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


high-density lipoprotein class complex location

A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:pde, GOC:rl]


discoidal high-density lipoprotein particle

nascent high-density lipoprotein particle

A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase). [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


mature high-density lipoprotein particle

spherical high-density lipoprotein particle

A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT). [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


The acquisition, loss or modification of a protein or lipid within a protein-lipid complex. [GOC:BHF, GOC:mah, GOC:rl]


The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT). [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


triacylglycerol-rich lipoprotein particle remodeling

triglyceride-rich lipoprotein particle remodeling

The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


very-low-density lipoprotein particle remodeling

The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


intermediate-density lipoprotein particle formation


intermediate-density lipoprotein particle remodeling

The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


low-density lipoprotein particle formation


low-density lipoprotein particle remodeling

The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


high-density lipoprotein particle remodeling

The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


conversion of discoidal HDL to spherical HDL

conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle

The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle. [GOC:BHF, GOC:mah, GOC:pde]


discoidal high-density lipoprotein remodeling


The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle. [GOC:BHF, GOC:mah]


The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron. [GOC:BHF, GOC:mah]


very-low-density lipoprotein particle assembly

The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle. [GOC:BHF, GOC:mah]


high-density lipoprotein particle assembly

The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. [GOC:BHF, GOC:mah]


The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:mah, GOC:tb]


The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded. [GOC:BHF, GOC:mah, GOC:pde]


low-density lipoprotein particle clearance

The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:mah]


high-density lipoprotein particle clearance

The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:mah]


gamma-aminobutyric acid pyruvate transaminase activity

Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine. [EC:2.6.1.96, GOC:mah]


25-30 S subcomplex of 90S preribosome location

Pwp2p-containing subcomplex of 90S preribosome location

A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p. [GOC:krc, PMID:15231838]


lipid particle organization and biogenesis

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle. [GOC:dph, GOC:jl, GOC:mah, PMID:18093937, PMID:18250201]


smooth muscle cell programmed cell death by apoptosis

programmed cell death of smooth muscle cells by apoptosis

programmed cell death, smooth muscle cells

Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. [CL:0000192, GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl]


regulation of smooth muscle cell apoptosis

regulation of smooth muscle cell apoptotic process

Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process. [GOC:BHF, GOC:mtg_apoptosis, GOC:rl]


down regulation of smooth muscle cell apoptosis

negative regulation of smooth muscle cell apoptosis

down-regulation of smooth muscle cell apoptosis

downregulation of smooth muscle cell apoptosis

negative regulation of smooth muscle cell apoptotic process

Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process. [GOC:BHF, GOC:mtg_apoptosis, GOC:rl]


inhibition of smooth muscle cell apoptosis


up-regulation of smooth muscle cell apoptosis

up regulation of smooth muscle cell apoptosis

upregulation of smooth muscle cell apoptosis

positive regulation of smooth muscle cell apoptosis

positive regulation of smooth muscle cell apoptotic process

Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process. [GOC:BHF, GOC:mtg_apoptosis, GOC:rl]


stimulation of smooth muscle cell apoptosis

activation of smooth muscle cell apoptosis


protein localization at cell surface
protein localisation at cell surface

A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane. [GOC:mah]


regulation of specific transcription from RNA polymerase II promoter in response to iron

regulation of transcription from RNA polymerase II promoter in response to iron

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus. [GO_REF:0000021, GOC:mah]


down regulation of transcription from RNA polymerase II promoter in response to iron

negative regulation of transcription from Pol II promoter in response to iron

downregulation of transcription from RNA polymerase II promoter in response to iron

down-regulation of transcription from RNA polymerase II promoter in response to iron

negative regulation of transcription from RNA polymerase II promoter in response to iron

Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus. [GOC:mah]


inhibition of transcription from RNA polymerase II promoter in response to iron


Any process in which a telomere is transported to, and/or maintained in, a specific location. [GOC:mah, GOC:vw]


The process in which a telomere is maintained in a specific location at the nuclear periphery. [GOC:mah]


The portion of the nuclear lumen proximal to the inner nuclear membrane. [GOC:krc, GOC:mah]


A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence. [PMID:12654863, PMID:24668747]


recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex

The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript. [PMID:18195044]


alignment of 3' and 5' splice sites of nuclear mRNA

alignment of 3' and 5' splice sites of mRNA

Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur. [GOC:krc, PMID:9430647]


nucleobase, nucleoside and nucleotide biosynthesis

nucleobase, nucleoside and nucleotide formation

nucleobase, nucleoside and nucleotide anabolism

nucleobase, nucleoside and nucleotide synthesis

nucleobase-containing small molecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. [GOC:mah]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface. [GOC:sl]


The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells. [GOC:mah]


cell wall 1,3-beta-D-glucan metabolic process

cell wall beta-1,3 glucan metabolic process

cell wall 1,3-beta-glucan metabolic process

cell wall (1->3)-beta-D-glucan metabolic process

The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. [GOC:mah]


ascospore wall beta-glucan metabolic process

The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores. [GOC:mah]


ascospore wall beta-1,3 glucan metabolism

ascospore wall beta-1,3 glucan metabolic process

ascospore wall 1,3-beta-D-glucan metabolic process

ascospore wall 1,3-beta-glucan metabolism

ascospore wall 1,3-beta-glucan metabolic process

ascospore wall (1->3)-beta-D-glucan metabolic process

The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. [GOC:mah]


cell wall beta-glucan biosynthesis
cell wall beta-glucan formation
cell wall beta-glucan synthesis
cell wall beta-glucan anabolism

cell wall beta-glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells. [GOC:mah]


cell wall 1,3-beta-D-glucan biosynthetic process

cell wall 1,3-beta-glucan biosynthetic process

cell wall beta-1,3-glucan biosynthetic process

cell wall (1->3)-beta-D-glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells. [GOC:mah]


ascospore wall beta-glucan biosynthesis
ascospore wall beta-glucan anabolism
ascospore wall beta-glucan formation
ascospore wall beta-glucan synthesis

ascospore wall beta-glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores. [GOC:mah]


ascospore wall 1,3-beta-glucan formation

ascospore wall beta-1,3-glucan biosynthesis

ascospore wall 1,3-beta-glucan anabolism

ascospore wall 1,3-beta-glucan biosynthesis

ascospore wall 1,3-beta-D-glucan biosynthetic process

ascospore wall 1,3-beta-glucan synthesis

ascospore wall beta-1,3-glucan biosynthetic process

ascospore wall 1,3-beta-glucan biosynthetic process

ascospore wall beta-1,3-glucan formation

ascospore wall beta-1,3-glucan synthesis

ascospore wall beta-1,3-glucan anabolism

ascospore wall (1->3)-beta-D-glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores. [GOC:mah]


endonucleolytic tRNA 3'-trailer cleavage

tRNA 3'-trailer cleavage, endonucleolytic

Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA. [GOC:mah]


exonucleolytic tRNA 3'-end cleavage
exonucleolytic tRNA 3'-trailer cleavage
tRNA 3'-end cleavage, exonucleolytic

tRNA 3'-trailer cleavage, exonucleolytic

Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA. [GOC:mah]


Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phospho-D-glycerate + phosphate. [EC:3.1.3.80, GOC:mah, PMID:18413611]


urate formation
urate anabolism
urate synthesis
uric acid biosynthetic process
urate biosynthesis

The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine. [GOC:mah]


cotranslational protein amino acid acetylation

co-translational protein amino acid acetylation

The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome. [GOC:mah]


post-translational protein amino acid acetylation

posttranslational protein amino acid acetylation

The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome. [GOC:mah]


The volume enclosed by the membrane of an aleurone grain. [GOC:rph]


The volume enclosed within the autophagosome double-membrane. [GOC:autophagy, GOC:rph]


A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins. [PMID:18216282]


The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. [GOC:mah]


Either of the lipid bilayers that surround a etioplast and form the etioplast envelope. [GOC:rph]


3'-5' exonucleolytic nuclear-transcribed mRNA catabolic process

nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'

The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. [GOC:krc, GOC:mah]


5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process

nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'

The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. [GOC:krc, GOC:mah]


Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain. [GOC:dsf, PMID:15065115, PMID:17507550, PMID:8038988]


lipid storage body surface lipid monolayer

monolayer-surrounded lipid storage body outer lipid monolayer

The single layer of phopholipids surrounding a lipid storage body. [GOC:rph]


diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity

Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate. [PMID:10085096, PMID:9450008, RHEA:32047]


diadenosine 5',5'''-P1,P6-pentaphosphate hydrolase activity

Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate. [PMID:10085096, PMID:9450008]


A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol). [GOC:BHF, GOC:mah, GOC:pde, GOC:rl]


A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol). [GOC:BHF, GOC:mah, GOC:pde, GOC:rl]


A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle. [GOC:BHF, GOC:mah, GOC:pde, GOC:rl]


The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:BHF, GOC:mah, GOC:rl]


The modification of a lipoprotein by oxidation of one or more amino acids in the protein. [GOC:BHF, GOC:mah]


The modification of a lipoprotein by oxidation of the lipid group. [GOC:BHF, GOC:mah]


The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen. [GOC:BHF, GOC:mah]


The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids. [GOC:BHF, GOC:mah]


Any process that modulates the frequency, rate or extent of lipoprotein oxidation. [GOC:BHF, GOC:mah]


negative regulation of lipoprotein oxidation

Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation. [GOC:BHF, GOC:mah]


negative regulation of plasma lipoprotein particle oxidation


inhibition of plasma lipoprotein oxidation


cell spreading during cell substrate adhesion

substrate adhesion dependent cell spreading

substrate adhesion-dependent cell spreading

The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate. [GOC:mah, GOC:pf, PMID:17050732]


very-low-density lipoprotein particle clearance

The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:rl]


Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. [GOC:mah, GOC:mcc, PMID:10089879, PMID:17190603]


Binding to a dynactin complex; a large protein complex that activates dynein-based motor activity. [GOC:BHF, GOC:mah]


Any process in which a microtubule is maintained in a specific location in a cell. [GOC:mah]


Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome. [GOC:BHF, GOC:mah]


Nan1p-containing subcomplex of 90S preribosome location

A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p. [GOC:krc, GOC:mah, GOC:vw, PMID:17515605]


Rrp7p-containing subcomplex of 90S preribosome location

A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p. [GOC:mah, PMID:17515605]


A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p. [GOC:mah, PMID:17515605]


ATP-dependent 3'-5' RNA helicase activity

ATP-dependent 3' to 5' RNA helicase activity

Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis. [GOC:jp]


The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane. [GOC:mah]


The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell. [GOC:mah, PMID:10704379]


small subunit processome assembly
SSU processome assembly

The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome. [GOC:mah]


The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions. [GOC:krc, GOC:mah, GOC:tb]


Bardet-Biedl syndrome complex
Bardet-Biedl syndrome complex location

A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B. [GOC:BHF, GOC:cilia, PMID:15231740, PMID:17574030, PMID:26498262]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus. [GOC:ecd]


The volume enclosed by the membrane of a chromaffin granule. [GOC:rph]


The volume enclosed by the membrane of an esterosome. [GOC:rph]


The volume enclosed by the membrane of a glycosome. [GOC:rph]


The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex. [GOC:mah]


Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules. [GOC:mah, PMID:27573892]


Any process involved in forming the mature 5' end of a non-coding RNA molecule. [GOC:mah]


Any process involved in forming the mature 3' end of an snRNA molecule. [GOC:mah]


Any process involved in forming the mature 3' end of a U1 snRNA molecule. [GOC:mah]


Any process involved in forming the mature 3' end of a U2 snRNA molecule. [GOC:mah]


Any process involved in forming the mature 3' end of a U4 snRNA molecule. [GOC:mah]


Any process involved in forming the mature 3' end of a U5 snRNA molecule. [GOC:mah]


Any process involved in forming the mature 3' end of a U6 snRNA molecule. [GOC:mah]


phosphatidylglycerol catabolism
phosphatidylglycerol degradation
phosphatidylglycerol breakdown

The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. [GOC:mah]


phosphatidylglycerol phospholipase C activity

Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate. [GOC:mah, PMID:18434318]


phospholipase C, acting on phosphatidylcholine

phosphatidylcholine phospholipase C activity

Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate. [EC:3.1.4.3, GOC:mah]


Clostridium oedematiens beta- and gamma-toxins activity


Clostridium welchii alpha-toxin activity


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate. [EC:2.8.2.17, EC:2.8.2.5, GOC:mah]


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues. [PMID:17227754]


heparan sulfate sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate. [GOC:mah]


raffinose catabolism
raffinose degradation
raffinose breakdown

The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside. [GOC:mah]


Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate. [GOC:pf]


The process in which a solute is transported from one side of the vacuolar membrane to the other. [GOC:mah]


vacuolar amino acid transmembrane transport

The process in which an amino acid is transported from one side of the vacuolar membrane to the other. [GOC:mah]


basic amino acid transmembrane import into vacuole

The directed movement of basic amino acids into the vacuole across the vacuolar membrane. [GOC:mah]


The volume enclosed by the hydrogenosome membrane. [GOC:rph]


The volume enclosed by the melanosome membrane. [GOC:rph]


The volume enclosed by the microneme membrane. [GOC:rph]


The volume enclosed by the protein storage vacuole membrane. [GOC:rph]


multivesicular body membrane disassembly

The controlled breakdown of the membranes of multivesicular bodies. [GOC:rb]


protein localisation to phagophore assembly site

protein localization to pre-autophagosomal structure

protein localization to phagophore assembly site

Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS). [GOC:rb]


post-Golgi endosome to Golgi transport
PGE to Golgi transport

The directed movement of substances from early endosomes to the Golgi. [GOC:rb]


prevacuolar endosome to Golgi transport
PVE to Golgi transport

The directed movement of substances from late endosomes to the Golgi. [GOC:rb]


Any process in which a protein is transported to, or maintained at, the kinetochore. [GOC:mah]


Any process in which a protein is transported to, or maintained at, a specific location on a chromosome. [GOC:mah]


protein localisation to nucleolar rDNA repeats

protein localization to nucleolar rDNA repeats

Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus. [GOC:mah]


condensin localization to nucleolar rDNA repeats


protein localization in nucleus
protein localisation to nucleus
protein localization in cell nucleus

A process in which a protein transports or maintains the localization of another protein to the nucleus. [GOC:ecd]


The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it. [GOC:mah, GOC:vw]


chromosome, centromeric outer repeat region

The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it. [GOC:mah, GOC:vw]


centromere assembly
chromosome, centromeric region assembly
centromere organization

The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere. [GOC:mah, GOC:vw]


The cell cycle process in which centromeres are physically detached from each other during chromosome separation. [GOC:mah]


Binding to a U3 small nucleolar RNA. [GOC:mah]


Binding to a box H/ACA small nucleolar RNA. [GOC:mah]


The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins. [GOC:mah, PMID:17849004]


An aggregation of proteasome core protease (CP) and regulatory particle (RP) complexes that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state. [GOC:krc, GOC:rb, PMID:18504300, PMID:30204036]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. [GOC:mah, GOC:rph]


The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation. [GOC:autophagy, PMID:18391941]


Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA. [GOC:mah]


cytoplasmic RNA cap binding complex location

A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA. [PMID:16405910]


Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+. [UM-BBD_reactionID:r0772]


Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+. [UM-BBD_reactionID:r0773]


Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-. [UM-BBD_reactionID:r0774]


Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide. [UM-BBD_reactionID:r0777]


Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2. [UM-BBD_reactionID:r0776]


Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+. [UM-BBD_reactionID:r0787]


Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O. [UM-BBD_reactionID:r0788]


Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene. [UM-BBD_reactionID:r0790]


Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate. [UM-BBD_reactionID:r0791]


Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate. [PMID:7710320]


Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+. [UM-BBD_reactionID:r0767]


Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde. [PMID:8042906]


Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate. [UM-BBD_reactionID:r0765]


Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate. [UM-BBD_reactionID:r0764]


Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O. [UM-BBD_reactionID:r0795]


Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+. [UM-BBD_reactionID:r0781]


Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate. [UM-BBD_reactionID:r0782]


Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde. [PMID:8042906]


Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+. [UM-BBD_reactionID:r0784]


3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity

Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr. [UM-BBD_reactionID:r0821]


3-monobromobisphenol A reductive dehalogenase activity

Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr. [UM-BBD_reactionID:r0824]


Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH. [UM-BBD_reactionID:r0806]


Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O. [UM-BBD_reactionID:r0807]


Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate. [UM-BBD_reactionID:r0809]


Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3. [UM-BBD_reactionID:r0810]


Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+. [UM-BBD_reactionID:r0811]


2,4-dichloroaniline reductive dehalogenase activity

Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl. [UM-BBD_reactionID:r0819]


Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3. [UM-BBD_reactionID:r0825]


Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3. [UM-BBD_reactionID:r0826]


N-cyclopropylammelide alkylamino hydrolase activity

Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid. [UM-BBD_reactionID:r0827]


Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O. [UM-BBD_reactionID:r0838]


mitochondrial cytochrome bc(1) complex assembly

mitochondrial respiratory chain complex III assembly

The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane. [GOC:dgf, GOC:mcc]


The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II. [GOC:dgf]


mitochondrial respiratory chain complex II assembly

The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane. [GOC:dgf]


3,3',5-tribromobisphenol A reductive dehalogenase activity

Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr. [UM-BBD_reactionID:r0842]


3,3'-dibromobisphenol A reductive dehalogenase activity

Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr. [UM-BBD_reactionID:r0844]


Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+. [UM-BBD_reactionID:r0849]


Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-. [UM-BBD_reactionID:r0859]


Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O. [UM-BBD_reactionID:r0860]


Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O. [UM-BBD_reactionID:r0861]


Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O. [UM-BBD_reactionID:r0862]


Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O. [UM-BBD_reactionID:r0864]


Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-. [UM-BBD_reactionID:r0867]


Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-. [UM-BBD_reactionID:r0866]


Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol. [UM-BBD_reactionID:r0872]


Catalysis of the reaction: chromate = chromium (III). [UM-BBD_reactionID:r0884]


Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-. [UM-BBD_reactionID:r0892]


Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-. [UM-BBD_reactionID:r0893]


Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-. [UM-BBD_reactionID:r0894]


Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid. [UM-BBD_reactionID:r0895]


Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-. [UM-BBD_reactionID:r0897]


Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline. [UM-BBD_reactionID:r0898]


Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-. [UM-BBD_reactionID:r0899]


Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-. [UM-BBD_reactionID:r0901]


Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate. [UM-BBD_reactionID:r0913]


Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone. [UM-BBD_reactionID:r0914]


Catalysis of the reaction: limonene + H2O = alpha-terpineol. [UM-BBD_reactionID:r0916]


Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate. [UM-BBD_reactionID:r0920]


Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-. [UM-BBD_reactionID:r0924]


Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA. [UM-BBD_reactionID:r0925]


Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-. [UM-BBD_reactionID:r0926]


Binding to a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. [GOC:kmv]


Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. [GOC:kmv]


The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. [GOC:kmv]


21U-RNA degradation
21U-RNA catabolism
21U-RNA breakdown

The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome. [GOC:kmv]


piRNA metabolism
Piwi-associated RNA metabolic process

The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. [GOC:kmv]


piRNA degradation
piRNA breakdown
piRNA catabolism
Piwi-associated RNA catabolic process

The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. [GOC:kmv]


The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah, PMID:14502423]


L-hydroxyproline transmembrane transporter activity

Enables the transfer of L-hydroxyproline from one side of a membrane to the other. [GOC:mah, PMID:14502423]


4-hydroxyproline transmembrane transporter activity


The volume enclosed by the rhoptry membrane. [GOC:rph, PMID:17997128]


The volume enclosed by the synaptic vesicle membrane. [GOC:rph]


phosphatidylinositol bisphosphate phosphatase activity

Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate. [GOC:mah]


phosphatidylinositol trisphosphate phosphatase activity

Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate. [GOC:mah]


polyphosphoinositol lipid 5-phosphatase activity

phosphatidylinositol phosphate 5-phosphatase activity

Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate. [GOC:elh]


phosphoinositide 4-phosphatase activity
PtdIns4P-phosphatase activity
PI(4)P-phosphatase activity
PI4P-phosphatase activity

phosphatidylinositol phosphate 4-phosphatase activity

Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate. [GOC:mah]


Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate. [GOC:mah]


Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product. [PMID:17303758, PMID:18084305]


Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. [GOC:mah]


oxoglutarate dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H. [EC:1.2.1.52, GOC:mah]


oxoglutarate dehydrogenase (NAD+) activity

Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH. [GOC:mah, RHEA:27786]


pyruvate dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H. [GOC:mah]


Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH. [GOC:mah, ISBN:0201090910]


Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. [GOC:mah]


The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate. [PMID:18050467, WB_REF:WBPaper00002109]


The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail. [PMID:18050467, WB_REF:WBPaper00002109]


Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate. [PMID:18050467]


Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva. [PMID:18050467]


Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates. [GOC:mah]


Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates. [GOC:mah]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus. [GOC:mah]


cellular response to active oxygen species

cellular response to reactive oxidative species

cellular response to reactive oxygen intermediate

cellular response to reactive oxygen species

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. [GOC:mah]


GCH1 complex location
GTP cyclohydrolase I complex
GTP cyclohydrolase I complex location

A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive. [PMID:16696853]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls. [GOC:ecd]


sapropterin binding
BH4 binding
H4biopterin binding

Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions. [GOC:BHF, GOC:mah, GOC:rl]


Binding to 2-amino-5-(carbamimidamido)pentanoic acid. [GOC:BHF, GOC:rl]


fatty acid elongation, monounsaturated fatty acid

Elongation of a fatty acid chain into which one C-C double bond has been introduced. [GOC:mah]


fatty acid elongation, polyunsaturated fatty acid

Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced. [GOC:mah]


The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. [GOC:imk, PMID:17161604]


nicotinamide nucleotide anabolism from aspartate

nicotinamide nucleotide formation from aspartate

nicotinamide nucleotide biosynthetic process from aspartate

de novo NAD biosynthetic process from aspartate

nicotinamide nucleotide synthesis from aspartate

'de novo' NAD biosynthetic process from aspartate

The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. [GOC:imk]


establishment and maintenance of RITS complex localization

Any process in which a RITS complex is transported to, or maintained in, a specific location. [GOC:mah]


attachment of spindle microtubules to spindle pole body

attachment of spindle microtubules to SPB

microtubule anchoring at spindle pole body

Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end. [GOC:mah, PMID:17486116]


retinol transporter activity
vitamin A1 transporter activity

retinol transmembrane transporter activity

Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. [GOC:BHF, GOC:mah, GOC:vk]


The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. [GOC:BHF, GOC:mah, GOC:vk]


glutathione transmembrane transporter activity

Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other. [GOC:mah]


The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


cellular carbohydrate biosynthetic process

The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells. [GOC:mah]


phosphatidylcholine catabolism
phosphatidylcholine breakdown
phosphatidylcholine degradation

The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. [GOC:jp]


L-amino acid export transporter activity

L-amino acid efflux transmembrane transporter activity

Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane. [GOC:mah]


mitochondrial localization by microtubule attachment

mitochondrial migration by microtubule attachment

establishment of mitochondrion localisation by microtubule attachment

mitochondrion migration by microtubule attachment

establishment of mitochondrion localization by microtubule attachment

The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization. [GOC:mah, PMID:12972644]


cellular nitrogen compound metabolic process

The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. [GOC:mah]


mitochondrial migration along microfilament

mitochondrion migration along microfilament

mitochondrion transport along actin filament

mitochondrial migration along actin filament

mitochondrion migration along actin filament

The directed movement of a mitochondrion along a microfilament, mediated by motor proteins. [GOC:mah, PMID:15979253, PMID:16306220]


establishment of mitochondrion localisation, microtubule-mediated

establishment of mitochondrion localization, microtubule-mediated

The directed movement of the mitochondrion to a specific location, by a process involving microtubules. [GOC:mah, PMID:12972644, PMID:15979253, PMID:16306220]


cellular response to ultraviolet radiation stimulus

cellular response to UV radiation stimulus

cellular response to ultraviolet light stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. [GOC:mah]


cellular biopolymer biosynthetic process

cellular macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells. [GOC:mah]


A lipid monolayer that surrounds and encloses an organelle. [GOC:mah]


histone demethylase activity (H3-K4-me3 specific)

histone demethylase activity (H3-trimethyl-K4 specific)

histone H3-tri/di/monomethyl-lysine-4 demethylase activity

Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate. [PMID:17550896, PMID:22473470]


The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties. [GOC:BHF, GOC:mah, GOC:rl]


cortisol biosynthesis
cortisol synthesis
cortisol formation

The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties. [GOC:BHF, GOC:mah, GOC:rl]


retinoic acid degradation
vitamin A1 acid catabolic process
retinoic acid breakdown
retinoic acid catabolism

The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A. [GOC:BHF, GOC:mah]


nucleobase, nucleoside, nucleotide and nucleic acid formation

nucleobase, nucleoside, nucleotide and nucleic acid anabolism

nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis

nucleobase-containing compound biosynthetic process

The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. [GOC:mah]


nucleobase, nucleoside, nucleotide and nucleic acid degradation

nucleobase, nucleoside, nucleotide and nucleic acid catabolism

nucleobase, nucleoside, nucleotide and nucleic acid breakdown

nucleobase-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids. [GOC:mah]


nucleobase, nucleoside and nucleotide breakdown

nucleobase, nucleoside and nucleotide degradation

nucleobase, nucleoside and nucleotide catabolism

nucleobase-containing small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. [GOC:mah]


A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p. [PMID:12686616, PMID:18508925]


isopropylmalate transmembrane transporter activity

Enables the transfer of isopropylmalate from one side of a membrane to the other. [GOC:mah]


The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs). [GOC:mah]


ncRNA catabolism
ncRNA breakdown
ncRNA degradation

The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs). [GOC:rb, PMID:18591258]


A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity. [PMID:16129695, PMID:16798722, PMID:16926444]


endoplasmic reticulum chaperone complex location

A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1. [PMID:12475965]


endoplasmic reticulum network complex location


immunoglobulin heavy chain-bound endoplasmic reticulum chaperone complex location

Ig heavy chain-bound endoplasmic reticulum chaperone complex location

Ig heavy chain-bound ER chaperone complex location

A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1. [PMID:12475965]


VLA-1 complex location
VLA-1 complex
alpha1-beta1 integrin complex location
alpha1-beta1 integrin complex
integrin alpha1-beta1 complex location

An integrin complex that comprises one alpha1 subunit and one beta1 subunit. [PMID:12297042]


VLA-2 complex
integrin alpha2-beta1 complex location
VLA-2 complex location

An integrin complex that comprises one alpha2 subunit and one beta1 subunit. [PMID:12297042]


VLA-3 complex location
alpha3-beta1 integrin complex
alpha3-beta1 integrin complex location
integrin alpha3-beta1 complex location
VLA-3 complex

An integrin complex that comprises one alpha3 subunit and one beta1 subunit. [PMID:12297042]


alpha4-beta1 integrin complex
integrin alpha4-beta1 complex location
VLA-4 complex
alpha4-beta1 integrin complex location
VLA-4 complex location

An integrin complex that comprises one alpha4 subunit and one beta1 subunit. [PMID:12297042]


alpha4-beta7 integrin complex
alpha4-beta7 integrin complex location
integrin alpha4-beta7 complex location

An integrin complex that comprises one alpha4 subunit and one beta7 subunit. [PMID:12297042]


The directed movement of a motile cell or organism in response to the presence of arachidonic acid. [GOC:go_curators, PMID:18202452]


retinoic acid receptor signaling pathway involved in pronephric kidney anterior/posterior pattern specification

retinoic acid receptor signalling pathway involved in pronephros anterior-posterior patterning

retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros. [GOC:mh]


A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B. [GOC:BHF, PMID:10746731]


alpha5-beta1 integrin complex
VLA-5 complex
VLA-5 complex location
alpha5-beta1 integrin complex location
integrin alpha5-beta1 complex location

An integrin complex that comprises one alpha5 subunit and one beta1 subunit. [PMID:12297042]


integrin alpha6-beta1 complex location
alpha6-beta1 integrin complex
alpha6-beta1 integrin complex location
VLA-6 complex
VLA-6 complex location

An integrin complex that comprises one alpha6 subunit and one beta1 subunit. [PMID:12297042]


alpha6-beta4 integrin complex
integrin alpha6-beta4 complex location
alpha6-beta4 integrin complex location

An integrin complex that comprises one alpha6 subunit and one beta4 subunit. [PMID:12297042]


alpha7-beta1 integrin complex
integrin alpha7-beta1 complex location
alpha7-beta1 integrin complex location

An integrin complex that comprises one alpha7 subunit and one beta1 subunit. [PMID:12297042]


integrin alpha8-beta1 complex location
alpha8-beta1 integrin complex location
alpha8-beta1 integrin complex

An integrin complex that comprises one alpha8 subunit and one beta1 subunit. [PMID:12297042]


alpha9-beta1 integrin complex location
alpha9-beta1 integrin complex
integrin alpha9-beta1 complex location

An integrin complex that comprises one alpha9 subunit and one beta1 subunit. [PMID:12297042]


integrin alpha10-beta1 complex location
alpha10-beta1 integrin complex
alpha10-beta1 integrin complex location

An integrin complex that comprises one alpha10 subunit and one beta1 subunit. [PMID:12297042]


alpha11-beta1 integrin complex
alpha11-beta1 integrin complex location
integrin alpha11-beta1 complex location

An integrin complex that comprises one alpha11 subunit and one beta1 subunit. [PMID:12297042]


alphav-beta1 integrin complex
alphav-beta1 integrin complex location
integrin alphav-beta1 complex location

An integrin complex that comprises one alphav subunit and one beta1 subunit. [PMID:12297042]


alphav-beta3 integrin complex
integrin alphav-beta3 complex location
alphav-beta3 integrin complex location

An integrin complex that comprises one alphav subunit and one beta3 subunit. [PMID:12297042]


integrin alphav-beta5 complex location
alphav-beta5 integrin complex location
alphav-beta5 integrin complex

An integrin complex that comprises one alphav subunit and one beta5 subunit. [PMID:12297042]


integrin alphav-beta6 complex location
alphav-beta6 integrin complex
alphav-beta6 integrin complex location

An integrin complex that comprises one alphav subunit and one beta6 subunit. [PMID:12297042]


alphav-beta8 integrin complex
integrin alphav-beta8 complex location
alphav-beta8 integrin complex location

An integrin complex that comprises one alphav subunit and one beta8 subunit. [PMID:12297042]


alphaL-beta2 integrin complex location
alphaL-beta2 integrin complex
integrin alphaL-beta2 complex location

An integrin complex that comprises one alphaL subunit and one beta2 subunit. [PMID:12297042]


integrin alphaM-beta2 complex location
alphaM-beta2 integrin complex location
alphaM-beta2 integrin complex

An integrin complex that comprises one alphaM subunit and one beta2 subunit. [PMID:12297042]


integrin alphaX-beta2 complex location
alphaX-beta2 integrin complex location
alphaX-beta2 integrin complex

An integrin complex that comprises one alphaX subunit and one beta2 subunit. [PMID:12297042]


integrin alphaD-beta2 complex location
alphaD-beta2 integrin complex
alphaD-beta2 integrin complex location

An integrin complex that comprises one alphaD subunit and one beta2 subunit. [PMID:12297042]


An integrin complex that comprises one alphaE subunit and one beta7 subunit. [PMID:12297042]


A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex. [PMID:8641291]


snRNP U11/U12
U11/U12 snRNP location
U11/U12 snRNP

A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins. [GOC:mah, PMID:15146077]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus. [GOC:BHF, GOC:vk]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus. [GOC:BHF, GOC:vk]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus. [GOC:BHF, GOC:vk]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus. [GOC:BHF, GOC:vk]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus. [GOC:BHF, GOC:vk]


response to luteinizing hormone stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus. [GOC:BHF, GOC:vk]


allulose 6-phosphate 3-epimerase activity

Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate. [GOC:imk]


Catalysis of the hydrolysis of a tripeptide. [GOC:mah]


A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. [GOC:mah, ISBN:071673706X]


An ion channel complex through which cations pass. [GOC:mah]


An ion channel complex through which calcium ions pass. [GOC:mah]


An ion channel complex through which potassium ions pass. [GOC:mah]


An ion channel complex through which sodium ions pass. [GOC:mah]


An ion channel complex through which chloride ions pass. [GOC:mah]


A protein complex that possesses methyltransferase activity. [GOC:mah]


20S methyltransferase complex location
20S methylosome
20S methyltransferase complex

A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains. [PMID:11713266, PMID:11756452]


Binding to an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit. [GOC:BHF, GOC:mah]


Binding to an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers. [GOC:BHF, GOC:mah]


transforming growth factor beta receptor type I binding

type I transforming growth factor beta receptor binding

Binding to a type I transforming growth factor beta receptor. [GOC:BHF, GOC:mah]


transforming growth factor beta receptor type III binding

type III transforming growth factor beta receptor binding

Binding to a type III transforming growth factor beta receptor. [GOC:BHF, GOC:mah]


pICln-Sm protein complex location
6S pICln complex
6S pICln complex location

A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG. [GOC:mah, PMID:11713266]


A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly. [GOC:mah, PMID:17640873]


A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly. [GOC:mah, PMID:17640873]


A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex. [GOC:mah, PMID:17640873]


A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm. [GOC:vw, PMID:11522829, PMID:17401408]


SMN-containing protein complex
SMN-containing protein complex location


The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone. [GOC:mah]


histone H3-K4 demethylation, trimethyl-H3-K4-specific

The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone. [GOC:mah]


Catalysis of the cleavage of a gamma-linked glutamate bond. [EC:3.4.19.9, MEROPS_fam:C26]


DNA replication-dependent nucleosome organization

DNA replication-dependent nucleosome organisation

DNA replication-dependent chromatin organization

The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation. [GOC:mah, PMID:17510629]


DNA replication-independent nucleosome organisation

DNA replication-independent chromatin organization

The formation or destruction of chromatin structures, occurring outside the context of DNA replication. [GOC:mah, PMID:17510629]


Degradation of a cell nucleus by lysosomal microautophagy. [GOC:autophagy, GOC:jp, PMID:18701704]


A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes. [GOC:mah]


histone lysine H3 K79 methylation
histone H3 K79 methylation
histone H3K79me

The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone. [GOC:se]


SmD-containing SMN-Sm protein complex location

An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex. [PMID:12975319, PMID:17401408]


Lsm-containing SMN-Sm protein complex location

An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA. [PMID:12975319, PMID:17401408]


transcription factor TFIIIB-alpha complex location

A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters. [PMID:11433012]


transcription factor TFIIIB-beta complex location

A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters. [PMID:11433012]


transcription factor TFIIIC1 complex location

A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity. [GOC:mah, PMID:11433012, PMID:15096501]


transcription factor TFIIIC2 complex location

A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter. [GOC:mah, PMID:11433012]


acyl coenzyme A-cholesterol-O-acyltransferase activity

acylcoenzyme A:cholesterol O-acyltransferase activity

Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA. [EC:2.3.1.26, RHEA:17729]


Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester. [GOC:mah]


Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester. [GOC:mah]


TFIIIC-Topoisomerase 1-PC4 complex location

A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III. [PMID:9660958]


A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization. [PMID:17126424]


A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. [PMID:15572129]


A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. [PMID:15572129]


A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration. [PMID:15572129]


A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration. [PMID:15572129]


A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity. [PMID:15556865]


A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation. [PMID:16611247]


A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation. [PMID:16611247]


aryl hydrocarbon receptor complex location

A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR. [GOC:mah, PMID:7598497]


cytosolic aryl hydrocarbon receptor complex location

An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP. [PMID:7598497, PMID:8937476, PMID:9447995]


9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex location


nuclear aryl hydrocarbon receptor complex location

An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT). [PMID:7598497]


6S-nuclear aryl hydrocarbon (Ah) receptor ligand-activated complex location


The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells. [GOC:mah]


iron ion membrane transport
transmembrane iron transport

A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah, PMID:11390404]


regulation of iron transport
regulation of Fe transport

Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


down regulation of iron ion transport
down-regulation of iron ion transport
negative regulation of iron transport
downregulation of iron ion transport

negative regulation of iron ion transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


up regulation of iron ion transport
upregulation of iron ion transport
positive regulation of iron transport
up-regulation of iron ion transport

positive regulation of iron ion transport

Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


regulation of iron ion membrane transport

regulation of transmembrane Fe transport

regulation of transmembrane iron transport

regulation of transmembrane iron ion transport

regulation of iron ion transmembrane transport

Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]


down regulation of transmembrane iron ion transport

negative regulation of transmembrane iron transport

negative regulation of transmembrane iron ion transport

downregulation of transmembrane iron ion transport

down-regulation of transmembrane iron ion transport

negative regulation of iron ion membrane transport

negative regulation of iron ion transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]


inhibition of transmembrane iron ion transport


positive regulation of iron ion membrane transport

up-regulation of transmembrane iron ion transport

positive regulation of transmembrane iron ion transport

positive regulation of transmembrane iron transport

upregulation of transmembrane iron ion transport

up regulation of transmembrane iron ion transport

positive regulation of iron ion transmembrane transport

Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]


stimulation of transmembrane iron ion transport

activation of transmembrane iron ion transport


Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. [GOC:mah]


down regulation of transmembrane transport

down-regulation of transmembrane transport

downregulation of transmembrane transport

negative regulation of membrane transport

negative regulation of transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. [GOC:mah]


positive regulation of membrane transport

up regulation of transmembrane transport

up-regulation of transmembrane transport

positive regulation of transmembrane transport

Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. [GOC:mah]


regulation of transmembrane ion transport

regulation of ion transmembrane transport

Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. [GOC:mah]


negative regulation of ion membrane transport

negative regulation of transmembrane ion transport

downregulation of transmembrane ion transport

down regulation of transmembrane ion transport

down-regulation of transmembrane ion transport

negative regulation of ion transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. [GOC:mah]


inhibition of transmembrane ion transport


upregulation of transmembrane ion transport

positive regulation of ion membrane transport

up regulation of transmembrane ion transport

positive regulation of transmembrane ion transport

up-regulation of transmembrane ion transport

positive regulation of ion transmembrane transport

Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. [GOC:mah]


stimulation of transmembrane ion transport

activation of transmembrane ion transport


Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate. [EC:4.2.3.106, PMID:12624761]


The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion. [GOC:sart, PMID:17301221]


histone lysine H4 K20 methylation
histone H4K20me
histone H4 K20 methylation

The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone. [GOC:mah]


histone lysine H4 K20 monomethylation
histone H4 K20 monomethylation

The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone. [GOC:mah]


histone lysine H4 K20 dimethylation
histone H4 K20 dimethylation

The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone. [GOC:mah]


histone H4 K20 trimethylation
histone lysine H4 K20 trimethylation

The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone. [GOC:mah]


The volume enclosed by the membrane of a secretory granule. [GOC:rph]


transmembrane glutathione transport
glutathione membrane transport

A process in which glutathione is transported across a membrane. [GOC:mah]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. [GOC:BHF, GOC:mah, GOC:vk]


The volume enclosed by the membranes of a recycling endosome. [GOC:rph]


Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-. [UM-BBD_reactionID:r1003]


Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA. [UM-BBD_reactionID:r1004]


Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-. [UM-BBD_reactionID:r0073]


Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate. [UM-BBD_reactionID:r1030]


Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2. [UM-BBD_reactionID:r1031]


Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP. [UM-BBD_reactionID:r1032]


Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. [UM-BBD_reactionID:r1033]


Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+. [UM-BBD_reactionID:r1034]


Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone. [UM-BBD_reactionID:r1039]


Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-. [UM-BBD_reactionID:r1040]


Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+. [UM-BBD_reactionID:r1041]


Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+. [UM-BBD_reactionID:r1042]


Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-. [UM-BBD_reactionID:r1043]


Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O. [UM-BBD_reactionID:r1053]


Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2. [UM-BBD_reactionID:r1058]


Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-. [UM-BBD_reactionID:r1056]


Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA. [UM-BBD_reactionID:r1057]


Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O. [GOC:dh, PMID:17526838, PMID:19383682]


Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-. [UM-BBD_reactionID:r1060]


fosfomycin 2-glutathione ligase activity

Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid. [UM-BBD_reactionID:r1073]