The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells. [PMID:17494872]


cellular response to oxygen-glucose deprivation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose. [GOC:sl, PMID:21525936]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose. [GOC:sl, PMID:21525936]


Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment. [GOC:sl, PMID:23644055, PMID:25934034]


The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion. [GOC:vw]


The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem. [PMID:25352850]


The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore. [PMID:19457051, PMID:25363531]


The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins. [PMID:19457051]


phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine

The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine. [MetaCyc:PWY-7470, PMID:24329598, PMID:27758859]


phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol

The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine. [MetaCyc:PWY-6826]


phosphatidylcholine biosynthesis from phosphatidylethanolamine

The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations. [MetaCyc:PWY-6825]


The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane. [PMID:20066089]


The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane. [PMID:20066089]


The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner. [PMID:20066089]


The directed killing of a target cell by a microglial cell. [GOC:BHF, GOC:nc, PMID:19100238]


G-protein coupled acetylcholine receptor signalling pathway involved in heart process

G-protein coupled acetylcholine receptor signaling pathway involved in heart process

G protein-coupled acetylcholine receptor signaling pathway involved in heart process

A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


negative regulation of pulmonary blood pressure

negative regulation of lung blood pressure

The process that decreases the force with which blood travels through the lungs. [GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:dph, PMID:22161164]


positive regulation of pulmonary blood pressure

positive regulation of lung blood pressure

The process that increases the force with which blood travels through the lungs. [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:22161164]


modulation by virus of host NIK/NF-kappaB signaling

modulation by virus of host NIK/NF-kappaB cascade

Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host. [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:26764146]


late endosome to lysosome transport via multivesicular body sorting pathway

The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome. [GOC:dph]


fusion of multivesicular body to lysosome

The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle. [GOC:dph, GOC:pad, GOC:PARL, PMID:21118109]


The series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity. [GOC:dph, GOC:pad, GOC:PARL, PMID:23010169, PMID:24709372]


latrophilin binding
lasso receptor binding

Binding to an alpha-latrotoxin receptor. [GOC:dph, PMID:21724987]


An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens. [GOC:dph, PMID:22470487]


2-hydroxyglutarate dehydrogenase activity, reverse reaction

Catalysis of the reaction: 2-oxoglutarate + reduced acceptor = (S)-2-hydroxyglutarate + acceptor. [EC:1.1.99.2, GOC:dph, PMID:26774271, RHEA:21254]


alpha-ketoglutarate reductase activity, reverse reaction

2-hydroxyglutarate dehydrogenase activity, forward reaction

Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor. [EC:1.1.99.2, GOC:dph, MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN]


leukocyte adhesion to arterial endothelial cell

The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules. [GOC:add, GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:22267480]


leukocyte adhesion to vascular endothelial cell

The attachment of a leukocyte to vascular endothelial cell via adhesion molecules. [GOC:add, GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:23897866]


positive regulation of circulating fibrinogen levels

Any process that increases the quantity of fibrinogen circulating in the bloodstream. [GOC:bf, GOC:BHF, GOC:BHF_miRNA, PMID:20570858]


negative regulation of circulating fibrinogen levels

Any process that reduces the quantity of fibrinogen circulating in the bloodstream. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:20570858]


substrate sequestration to autophagosome

The localization process by which an autophagic substrate is delivered to a forming autophagosome. [GOC:dph, GOC:pad, GOC:PARL, PMID:23545414]


Binding to long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats. [GOC:BHF, GOC:BHF_telomere, GOC:dph, GOC:jbu, PMID:20655916]


Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis. [GOC:dph, PMID:26277776]


single-stranded DNA-dependent CTPase activity


Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience. [GOC:bf, GOC:PARL, Wikipedia:Motor_learning]


protein targeting to lysosome involved in chaperone-mediated autophagy

The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor. [GOC:dph, GOC:pad, GOC:PARL, PMID:22748206]


protein lipidation involved in autophagosome assembly

The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly. [GOC:autophagy, GOC:dph, PMID:11096062, PMID:11100732, PMID:15277523]


The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment. [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:21238931]


A G protein-coupled receptor signaling pathway initiated by leukotriene binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:dph, PMID:21771892]


The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy. [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL]


dynamin-like protein-mediated stimulation of mitophagy in response to mitochondrial depolarization

DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization

A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule. [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:25349190]


PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization

Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization

parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule. [GOC:autophagy, GOC:dph, GOC:pad, GOC:PARL, PMID:25349190]


Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide. [GOC:dph]


mitochondrial acetyl-CoA biosynthetic process from pyruvate

The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA. [GOC:dph, ISBN:0201090910]


Binding to C-rich, single-stranded, telomere-associated DNA. [GOC:dph, GOC:kmv, PMID:18329362]


GDP-mannose biosynthetic process from fructose-6-phosphate

The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate. [GOC:dph, PMID:16339137]


GDP-mannose biosynthetic process from mannose

The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose. [GOC:dph, PMID:16339137, PMID:24218558]


methylglyoxal catabolic process to lactate

The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate. [GOC:dph, PMID:2198020]


The disaggregation of a mitochondrion into its constituent components. [GOC:autophagy, PMID:25009776]


The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases. [GOC:autophagy]


The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions. [GOC:autophagy, PMID:23708524, PMID:26076903]


The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions. [GOC:autophagy, PMID:21893048]


The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate. [GOC:dph, PMID:24463506]


6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)

The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-). [GOC:dph, PMID:14602517, PMID:24463506]


6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde

The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). [GOC:dph, PMID:24463506]


glucose catabolic process to pyruvate utilizing ADP

The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions. [GOC:dph, MetaCyc:P341-PWY]


The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate. [GOC:dph]


The directed movement of a processed miRNA from the nucleus to the cytoplasm. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:15738428, PMID:21554756]


Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis. [GOC:BHF, GOC:hal]


The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline. [GOC:BHF, GOC:dph, GOC:hal, PMID:17286298]


Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine. [EC:2.8.4.5]


Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA. [EC:2.3.1.234]


Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O. [EC:2.7.7.87]


ER autophagy
reticulophagy
endoplasmic reticulum autophagy
autophagy of the endoplasmic reticulum
autophagy of the ER

The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions. [GOC:autophagy, GOC:dph, PMID:22481944, PMID:24060720, PMID:26040717]


Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+. [GOC:dph, PMID:15509579]


The single-organism macropinocytosis process that results in the uptake of an extracellular exosome. [GOC:dph, PMID:24951588]


glycolytic process from sucrose through glucose and fructose

The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. [GOC:dph, GOC:glycolysis, MetaCyc:PWY-1042, PMID:15012287]


sucrose catabolic process to fructose-6-phosphate through glucose and fructose

The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates. [GOC:dph, GOC:glycolysis, MetaCyc:PWY-621, PMID:15012287]


The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. [GOC:dph, GOC:glycolysis, PMID:15012287]


A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes. [GOC:dph, GOC:pr, PMID:20596524]


The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein. [GOC:dph, PMID:24703693]


The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein. [GOC:dph, PMID:24703693]


Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. [GOC:dph, PMID:24703693]


alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity

Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine. [EC:2.7.8.37, GOC:dph, PMID:22089136]


cellular detoxification of hydrogen peroxide

Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration. [GOC:dph, GOC:vw]


Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein. [GOC:dph, PMID:14086741]


An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet. [GOC:dk, GOC:dph, PMID:22520461, PMID:25822906]


calcium ion transmembrane transport via high voltage-gated calcium channel

A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel. [GOC:dph]


ADP-activated adenosine receptor activity


ATP-activated adenosine receptor activity


signal transduction involved in mitotic cytokinesis checkpoint

signalling pathway involved in mitotic cytokinesis checkpoint

signaling pathway involved in mitotic cytokinesis checkpoint

signalling cascade involved in mitotic cytokinesis checkpoint

mitotic cytokinesis checkpoint signaling

A signaling process that contributes to a mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed. [GOC:jl, GOC:mtg_cell_cycle, PMID:17538026]


astrocyte-dopaminergic neuron cell signaling

Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron. [GOC:bf, GOC:PARL, PMID:12794311, PMID:21752258]


chemorepulsion of serotonergic neuron axon

The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. [CL:0000850, GOC:bf, GOC:PARL, PMID:21106844]


chemoattraction of 5-HT axon
chemoattraction of serotonergic axon

chemoattraction of serotonergic neuron axon

The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal. [CL:0000850, GOC:bf, GOC:PARL, PMID:21106844]


chemoattraction of DA axon
chemoattraction of dopaminergic axon

chemoattraction of dopaminergic neuron axon

The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal. [GOC:bf, GOC:PARL, PMID:21106844]


serotonergic axon guidance
5-HT axon guidance

The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues. [CL:0000850, GOC:bf, GOC:PARL, PMID:21106844]


DA axon guidance
mdDA axon guidance
dopaminergic axon guidance

The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues. [GOC:bf, GOC:PARL, PMID:21106844, PMID:23517308]


The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. [GOC:bf, GOC:PARL, PMID:12829701]


The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. [GOC:bf, GOC:PARL, PMID:12829701]


glycoprotein mannose trimming on C branch

trimming of terminal mannose on C branch

The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. [GOC:bf, GOC:PARL, PMID:20065073]


glycoprotein mannose trimming on B branch

trimming of terminal mannose on B branch

The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum. [GOC:bf, GOC:PARL, KEGG_REACTION:R06722, PMID:22160784]


The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein. [GOC:bf, GOC:PARL, PMID:21062743, PMID:25092655]


The removal of one or more mannose residues from a mannosylated protein. [GOC:bf, GOC:PARL, PMID:25092655]


Maintaining a protein in an unfolded, soluble state. [GOC:bf, GOC:BHF, GOC:nc, GOC:PARL, PMID:21636303]


Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D). [GOC:bf, GOC:PARL, PMID:23690594, PMID:9388493]


membrane fusion involved in Golgi reassembly

The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. [GOC:bf, GOC:PARL, PMID:12473691]


The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure. [GOC:mtg_sensu, ISBN:0815316194, PMID:11121786]


glial cell-derived neurotrophic factor receptor binding

A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors. [GOC:vw, PMID:11476867]


The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types. [GOC:mah, ISBN:0878932437]


The directed movement of organelles or molecules along microtubules in neuron projections. [ISBN:0815316194]


mRNA 3'-end processing by stem-loop binding and cleavage

Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine. [GOC:mah, GOC:tb, PMID:17998288]


downregulation of photosynthesis
down-regulation of photosynthesis


upregulation of voltage gated sodium channel activity

up regulation of voltage-sensitive sodium channel

up-regulation of voltage-dependent sodium channel activity

up-regulation of voltage-sensitive sodium channel

upregulation of voltage-dependent sodium channel activity

upregulation of voltage-sensitive sodium channel

up-regulation of voltage-gated sodium ion channel activity

up-regulation of voltage gated sodium channel activity

upregulation of voltage-gated sodium ion channel activity

upregulation of voltage-gated sodium channel activity

up regulation of voltage-dependent sodium channel activity

up regulation of voltage-gated sodium ion channel activity

up-regulation of voltage-gated sodium channel activity

up regulation of voltage-gated sodium channel activity

up regulation of voltage gated sodium channel activity


down-regulation of voltage-gated sodium channel activity

down regulation of voltage-gated sodium channel activity

down regulation of voltage-sensitive sodium channel

downregulation of voltage gated sodium channel activity

down-regulation of voltage-gated sodium ion channel activity

down regulation of voltage-dependent sodium channel activity

downregulation of voltage-gated sodium ion channel activity

downregulation of voltage-gated sodium channel activity

down-regulation of voltage-dependent sodium channel activity

downregulation of voltage-sensitive sodium channel

downregulation of voltage-dependent sodium channel activity

down regulation of voltage-gated sodium ion channel activity

down-regulation of voltage gated sodium channel activity

down-regulation of voltage-sensitive sodium channel

down regulation of voltage gated sodium channel activity


upregulation of canonical Wnt receptor signaling pathway involved in heart development

up-regulation of canonical Wnt receptor signaling pathway involved in heart development

up-regulation of canonical Wnt signaling pathway involved in heart development

up regulation of canonical Wnt receptor signalling pathway involved in heart development

upregulation of canonical Wnt receptor signalling pathway involved in heart development

up-regulation of canonical Wnt-activated signaling pathway involved in heart development

up regulation of canonical Wnt-activated signaling pathway involved in heart development

upregulation of canonical Wnt-activated signaling pathway involved in heart development

upregulation of canonical Wnt signaling pathway involved in heart development

up regulation of canonical Wnt signaling pathway involved in heart development

up-regulation of canonical Wnt receptor signalling pathway involved in heart development

up regulation of canonical Wnt receptor signaling pathway involved in heart development


up regulation of L-lysine import into cell

upregulation of L-lysine import into cell

up-regulation of L-lysine import into cell

positive regulation of L-lysine import into cell

positive regulation of L-lysine import across plasma membrane

Any process that activates or increases the frequency, rate or extent of L-lysine import into cell. [GO_REF:0000058, GOC:TermGenie, PMID:7499219]


down regulation of establishment of macromolecular complex localisation to telomere

down-regulation of establishment of macromolecular complex localization to telomere

down regulation of establishment of macromolecular complex localization to telomere

negative regulation of establishment of macromolecular complex localisation to telomere

negative regulation of establishment of macromolecular complex localization to telomere

down-regulation of establishment of macromolecular complex localisation to telomere

downregulation of establishment of macromolecular complex localisation to telomere

downregulation of establishment of macromolecular complex localization to telomere

negative regulation of establishment of protein-containing complex localization to telomere

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere. [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:rph, GOC:TermGenie, PMID:26586433]


up-regulation of protein localization in cell-cell adherens junction

up regulation of protein localization in cell-cell adherens junction

up regulation of protein localisation in cell-cell adherens junction

upregulation of protein localization in cell-cell adherens junction

up regulation of protein localization to cell-cell adherens junction

up-regulation of protein localization to cell-cell adherens junction

upregulation of protein localisation to cell-cell adherens junction

upregulation of protein localisation in cell-cell adherens junction

up-regulation of protein localisation in cell-cell adherens junction

upregulation of protein localization to cell-cell adherens junction

up-regulation of protein localisation to cell-cell adherens junction

up regulation of protein localisation to cell-cell adherens junction

positive regulation of protein localization to adherens junction

Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:kmv, GOC:TermGenie, PMID:26412237]


upregulation of neuromuscular junction development

upregulation of neuromuscular junction organization

up regulation of neuromuscular junction organization

up-regulation of neuromuscular junction organization

up-regulation of neuromuscular junction development

up regulation of neuromuscular junction development


downregulation of neuromuscular junction development

down-regulation of neuromuscular junction organization

downregulation of neuromuscular junction organization

down regulation of neuromuscular junction organization

down-regulation of neuromuscular junction development

down regulation of neuromuscular junction development


upregulation of convergent extension involved in rhombomere morphogenesis

up-regulation of convergent extension involved in rhombomere morphogenesis

up regulation of convergent extension involved in rhombomere morphogenesis


down-regulation of convergent extension involved in somitogenesis

downregulation of convergent extension involved in somitogenesis

down regulation of convergent extension involved in somitogenesis


upregulation of fatty acid beta-oxidation by octopamine signaling pathway

up-regulation of fatty acid beta-oxidation by octopamine signaling pathway

up regulation of fatty acid beta-oxidation by octopamine signaling pathway


A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach. [ISBN:0198506732]


Any microtubule in the cytoplasm of a cell. [GOC:mah]


An infolding of the plasma membrane. [GOC:dos, GOC:vw]


viral entry into host cell via membrane fusion with the plasma membrane


Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection. [ISBN:0781718325, UniProtKB-KW:KW-0917, VZ:1946]


A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signalling and metabolism, and in calcium signalling. [GOC:cilia, PMID:19879876, PMID:26199333, PMID:26688619]


A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle. [GOC:cilia, PMID:13978319, PMID:25686250]


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphoric acid. [EC:4.2.3.61, GOC:pz]


The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body. [GOC:dos]

anterograde dendritic transport of mitochondrion


anterograde axonal transport of mitochondrion

The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. [GOC:dos]

anterograde axon transport of mitochondria


Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR). [GOC:dph, GOC:pad, GOC:PARL, PMID:11866528]


Catalysis of the reaction: H+ + (3S,6E)-nerolidol + NADPH + O2 <=> (E)-4,8-dimethyl-1,3,7-nonatriene + buten-2-one + NADP + 2 H2O. [EC:1.14.13.-, GOC:pz]


establishment of ER localization to postsynapse

The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine. [GOC:dos, PMID:21151132]

establishment of endoplasmic reticulum localization to postsynapse


The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments. [GOC:krc, PMID:22319670, PMID:24440897, PMID:26792866]


intrinsic component of dense core granule membrane

The component of the dense core granule membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. [GOC:dos, GOC:mah]

intrinsic to dense core granule membrane


intrinsic to neuronal dense core granule membrane

The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. [GOC:dos, GOC:mah]

intrinsic component of neuronal dense core vesicle membrane


Catalysis of the reaction: (4R)-limonene + O2 + NADH + H+ <=> (4R)-perillyl alcohol + NAD + H2O. [EC:1.14.13.-, GOC:pz]


maintenance of protein location at cell tip

Any process in which localization of a protein is maintained at the cell tip. [GOC:dos, GOC:vw, PMID:12894167]

maintenance of protein localization at cell tip


maintenance of protein localization at growing cell tip

Any process in which localization of a protein is maintained at the growing cell tip. [GOC:dos, GOC:vw, PMID:24146635]

maintenance of protein location at growing cell tip


A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules). [GOC:pr]


perisynaptic ECM
perisynaptic extracellular matrix

The portion of the extracellular matrix that lies within the perisynaptic space. [GOC:dos]


neurotransmitter receptor transport, postsynaptic endosome to lysosome

The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation. [GOC:dos]

postsynaptic neurotransmitter receptor endosomal trafficking


neurotransmitter receptor transport, endosome to postsynaptic membrane

The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles. [GOC:dos]


retrograde axonal transport of mitochondrion

The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse. [GOC:dos]

retrograde axon transport of mitochondria


retrograde dendrite transport of mitochondria

The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse. [GOC:dos]

retrograde dendritic transport of mitochondrion


Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template. [GOC:pf]


Any process that modifies the structure of a postsynapse. [GOC:dos]


A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles. Synaptic ribbons may be plate like or spherical. [PMID:15626493]


A T-shaped presynpatic density. These are common in arhropod central nervous systems. [GOC:dos, PMID:26780543]


Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucopyranose <=> alpha,alpha-trehalose + H+ + a nucleoside diphosphate. [EC:2.4.1.245, GOC:pz]


The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit. [GOC:ch, GOC:jh2, PMID:18687036]


Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA. [GOC:dph, GOC:mah, PMID:27697832]

regulation of DNA recombination at centromere


negative regulation of centromeric recombination

Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere. [GOC:dph, GOC:mah]

negative regulation of DNA recombination at centromere


A vesicle derived via budding from a mitochondrion. These vesicles often contain inner membrane and, much more rarely, cristae. [GOC:bc, GOC:pad, GOC:PARL-UCL, PMID:18207745, PMID:20619655, PMID:22226745, PMID:23300790]


A sensory perception which causes the desire or reflex to scratch. [PMID:26015312, PMID:29723501, PMID:30734045, Wikipedia:Itch]


down-regulation of motile primary cilia assembly

downregulation of motile primary cilia assembly

downregulation of motile primary cilium assembly

down-regulation of motile primary cilium assembly

down regulation of motile primary cilium assembly

down regulation of motile primary cilia assembly


downregulation of cytochrome aa3 activity

down-regulation of cytochrome aa3 activity

down regulation of cytochrome aa3 activity


distal appendage of mother centriole assembly


vacuolar protein sorting-associated complex location


inhibition of protein localization to kinetochore

inhibition of protein localisation to kinetochore


activation of morphogenesis of an epithelium


inhibition of synapse organization and biogenesis


One of the two nuclear divisions that occur as part of the meiotic cell cycle. [PMID:9334324]


The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. [PMID:18622392, PMID:23192658, Wikipedia:Human_iron_metabolism]


nonmotile primary cilia
immotile primary cilium


Rad51 nucleoprotein filament disassembly


transmembrane actin-associated (TAN) line

A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge). [GOC:hjd, PMID:21173262]


Platelet glycoprotein Ia* complex location


Elastic microfibrillar interface 4 complex location


Elastic microfibrillar interface 3 complex location


Elastic microfibrillar interface 2 complex location


Elastic microfibrillar interface 1 complex location


modulation by host of viral Tat activity


modulation by host of viral protein:RNA interaction


establishment of blood-retina barrier
establishment of BRB

Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type. [PMID:25053619]


VPS4A/B complex
VPS4A/B complex location


Palmitoyltransferase ERF2/SHR5 complex location

Palmitoyltransferase ERF2-SHR5 complex location


response to differentiation-inducing factor 2

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus. [GO_REF:0000071, GOC:rjd, GOC:TermGenie, PMID:19684855, PMID:3355503]


activation of cellular response to alcohol


inhibition of cellular response to alcohol


activation of endothelial tube morphogenesis


inhibition of endothelial tube morphogenesis


inhibition of calcium ion import across plasma membrane


activation of formation of growth cone in injured axon


inhibition of formation of growth cone in injured axon


upregulation of VSMC differentiation involved in phenotypic dimorphism

up-regulation of VSMC differentiation involved in phenotypic dimorphism

up regulation of VSMC differentiation involved in phenotypic dimorphism

positive regulation of VSMC differentiation involved in phenotypic dimorphism


up-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

upregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

up regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

positive regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism


upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism

up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism

up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism

positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism


activation of vascular smooth muscle cell differentiation involved in phenotypic switching

activation of VSMC differentiation involved in phenotypic switching


activation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

activation of VSMC differentiation involved in phenotypic dimorphism


activation of vascular associated smooth muscle cell differentiation involved in phenotypic switching


activation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism


negative regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

negative regulation of VSMC differentiation involved in phenotypic dimorphism


negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism


inhibition of vascular smooth muscle cell differentiation involved in phenotypic switching

inhibition of VSMC differentiation involved in phenotypic switching


inhibition of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

inhibition of VSMC differentiation involved in phenotypic dimorphism


inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic switching


inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism


down-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

down regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

downregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

down-regulation of VSMC differentiation involved in phenotypic dimorphism

downregulation of VSMC differentiation involved in phenotypic dimorphism

down regulation of VSMC differentiation involved in phenotypic dimorphism


down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism

downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism

down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism


regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism

regulation of VSMC differentiation involved in phenotypic dimorphism


regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism


activation of acetylcholine biosynthetic process


activation of acetylcholine biosynthesis


inhibition of acetylcholine biosynthetic process


inhibition of acetylcholine biosynthesis


activation of cell differentiation involved in phenotypic switching


inhibition of cell differentiation involved in phenotypic switching


activation of calcium ion export from cell


activation of calcium ion efflux from cell


inhibition of calcium ion export from cell


inhibition of calcium ion efflux from cell


activation of nematode entry into dormancy


inhibition of nematode entry into dormancy


upregulation of amyloid structure formation

up-regulation of amyloid structure formation

up regulation of amyloid structure formation


up-regulation of amyloid structure assembly

upregulation of amyloid structure assembly

up regulation of amyloid structure assembly


up-regulation of amyloid fibril assembly

up regulation of amyloid fibril assembly


positive regulation of amyloid structure formation


positive regulation of amyloid structure assembly


positive regulation of amyloid fibril assembly


activation of amyloid structure formation


activation of amyloid structure assembly


negative regulation of amyloid structure formation


negative regulation of amyloid structure assembly


negative regulation of amyloid fibril assembly


inhibition of amyloid structure formation


inhibition of amyloid structure assembly


down-regulation of amyloid structure formation

downregulation of amyloid structure formation

down regulation of amyloid structure formation


downregulation of amyloid structure assembly

down-regulation of amyloid structure assembly

down regulation of amyloid structure assembly


down-regulation of amyloid fibril assembly

downregulation of amyloid fibril assembly

down regulation of amyloid fibril assembly


regulation of amyloid structure formation


regulation of amyloid structure assembly


activation of smooth muscle tissue development


inhibition of smooth muscle tissue development


activation of response to endoplasmic reticulum stress


activation of cellular response to endoplasmic reticulum stress


activation of cellular response to tunicamycin


inhibition of cellular response to tunicamycin


activation of cellular response to thapsigargin


inhibition of cellular response to thapsigargin


activation of cellular response to very-low-density lipoprotein particle stimulus

activation of cellular response to VLDL particle stimulus


inhibition of cellular response to very-low-density lipoprotein particle stimulus

inhibition of cellular response to VLDL particle stimulus


activation of postsynaptic density organization

activation of postsynaptic density organisation

activation of post synaptic density organization

activation of post-synaptic density organization


inhibition of postsynaptic density organisation

inhibition of post-synaptic density organization

inhibition of post synaptic density organization

inhibition of postsynaptic density organization


activation of protein localization to cell leading edge

activation of protein localisation to cell leading edge


activation of protein localization in cell leading edge

activation of protein localisation in cell leading edge


inhibition of protein localization to cell leading edge

inhibition of protein localisation to cell leading edge


inhibition of protein localization in cell leading edge

inhibition of protein localisation in cell leading edge


activation of 3'-untranslated region-mediated mRNA stabilization

activation of 3'-UTR-mediated mRNA stabilization


inhibition of 3'-untranslated region-mediated mRNA stabilization

inhibition of 3'-UTR-mediated mRNA stabilization


activation of ULK1-ATG13-RB1CC1 complex formation


activation of ULK1-ATG13-RB1CC1 complex assembly


activation of ULK1-ATG13-FIP200 complex formation


activation of ULK1-ATG13-FIP200 complex assembly


activation of ULK1 signaling complex formation


activation of ULK1 signaling complex assembly


activation of Atg1p signalling complex formation


activation of Atg1p signalling complex assembly


activation of ATG1/ULK1 signaling complex formation


activation of ATG1/ULK1 signaling complex assembly


activation of ATG1/ULK1 kinase complex formation


activation of ATG1/ULK1 kinase complex assembly


activation of ATG1-ATG13 complex formation


activation of ATG1-ATG13 complex assembly


activation of ATG1 kinase complex formation


activation of ATG1 kinase complex assembly


inhibition of ULK1-ATG13-RB1CC1 complex formation


inhibition of ULK1-ATG13-RB1CC1 complex assembly


inhibition of ULK1-ATG13-FIP200 complex formation


inhibition of ULK1-ATG13-FIP200 complex assembly


inhibition of ULK1 signaling complex formation


inhibition of ULK1 signaling complex assembly


inhibition of Atg1p signalling complex formation


inhibition of Atg1p signalling complex assembly


inhibition of ATG1/ULK1 signaling complex formation


inhibition of ATG1/ULK1 signaling complex assembly


inhibition of ATG1/ULK1 kinase complex formation


inhibition of ATG1/ULK1 kinase complex assembly


inhibition of ATG1-ATG13 complex formation


inhibition of ATG1-ATG13 complex assembly


inhibition of ATG1 kinase complex formation


inhibition of ATG1 kinase complex assembly


up-regulation of heparin proteoglycan binding

upregulation of heparin proteoglycan binding

up regulation of heparin proteoglycan binding


positive regulation of heparin proteoglycan binding


activation of heparin proteoglycan binding


activation of heparan sulfate proteoglycan binding


negative regulation of heparin proteoglycan binding


inhibition of heparin proteoglycan binding


inhibition of heparan sulfate proteoglycan binding


downregulation of heparin proteoglycan binding

down-regulation of heparin proteoglycan binding

down regulation of heparin proteoglycan binding


regulation of heparin proteoglycan binding


activation of cellular response to oxidopamine


inhibition of cellular response to oxidopamine


upregulation of cellular response to gamma-ray photon

up-regulation of cellular response to gamma-ray photon

up regulation of cellular response to gamma-ray photon


upregulation of cellular response to gamma ray

up-regulation of cellular response to gamma ray

up regulation of cellular response to gamma ray


positive regulation of cellular response to gamma-ray photon


positive regulation of cellular response to gamma ray


activation of cellular response to gamma-ray photon


activation of cellular response to gamma ray


activation of cellular response to gamma radiation


negative regulation of cellular response to gamma-ray photon


negative regulation of cellular response to gamma ray


inhibition of cellular response to gamma-ray photon


inhibition of cellular response to gamma ray


inhibition of cellular response to gamma radiation


down-regulation of cellular response to gamma-ray photon

downregulation of cellular response to gamma-ray photon

down regulation of cellular response to gamma-ray photon


down-regulation of cellular response to gamma ray

downregulation of cellular response to gamma ray

down regulation of cellular response to gamma ray


regulation of cellular response to gamma-ray photon


regulation of cellular response to gamma ray


activation of telomeric D-loop disassembly


inhibition of telomeric D-loop disassembly


activation of bipolar spindle biosynthesis


inhibition of bipolar spindle biosynthesis


activation of prostaglandin catabolic process


inhibition of prostaglandin catabolic process


activation of selenocysteine metabolic process


inhibition of selenocysteine metabolic process


activation of mitotic sister chromatid arm separation


inhibition of mitotic sister chromatid arm separation


activation of nuclear chromosome condensation


activation of eukaryotic chromosome condensation


up-regulation of rDNA separation
upregulation of rDNA separation


up-regulation of chromatid release
upregulation of chromatid release


positive regulation of chromatid release


negative regulation of chromatid release


downregulation of rDNA separation
down-regulation of rDNA separation


downregulation of chromatid release
down-regulation of chromatid release


activation of dorsal/ventral axon guidance

activation of dorsoventral axon guidance

activation of dorsal-ventral axon guidance


activation of dorsal/ventral axon pathfinding


inhibition of dorsal/ventral axon guidance

inhibition of dorsoventral axon guidance

inhibition of dorsal-ventral axon guidance


inhibition of dorsal/ventral axon pathfinding


activation of motor neuron axon guidance


inhibition of motor neuron axon guidance


inhibition of excitatory synapse disassembly


negative regulation of synapse organization and biogenesis


negative regulation of synapse morphogenesis


down-regulation of synapse organization and biogenesis

downregulation of synapse organization and biogenesis

down regulation of synapse organization and biogenesis


down-regulation of synapse morphogenesis

down regulation of synapse morphogenesis


activation of cellular response to manganese ion


activation of cellular response to manganese


inhibition of cellular response to manganese ion


inhibition of cellular response to manganese


activation of intraflagellar retrograde transport


activation of intraciliary retrograde transport


inhibition of intraflagellar retrograde transport


inhibition of intraciliary retrograde transport


activation of intraflagellar anterograde transport


activation of intraciliary anterograde transport


inhibition of intraflagellar anterograde transport


inhibition of intraciliary anterograde transport


activation of behavioural response to mechanical stimulus

activation of behavioral response to mechanical stimulus


inhibition of behavioural response to mechanical stimulus

inhibition of behavioral response to mechanical stimulus


activation of tactition, sensory detection of mechanical stimulus


activation of sensory transduction of mechanical stimulus during perception of touch


activation of sensory detection of mechanical stimulus during perception of touch


activation of perception of touch, sensory transduction of mechanical stimulus


activation of perception of touch, sensory detection of mechanical stimulus


activation of perception of touch, detection of mechanical stimulus


activation of detection of mechanical stimulus involved in sensory perception of touch


inhibition of tactition, sensory detection of mechanical stimulus


inhibition of sensory transduction of mechanical stimulus during perception of touch


inhibition of sensory detection of mechanical stimulus during perception of touch


inhibition of perception of touch, sensory transduction of mechanical stimulus


inhibition of perception of touch, sensory detection of mechanical stimulus


inhibition of perception of touch, detection of mechanical stimulus


inhibition of detection of mechanical stimulus involved in sensory perception of touch


activation of phosphatidylserine exposure on apoptotic cell surface


activation of externalization of phosphatidylserine


inhibition of phosphatidylserine exposure on apoptotic cell surface


inhibition of externalization of phosphatidylserine


up-regulation of exonuclease IX activity

up regulation of exonuclease IX activity


positive regulation of exonuclease IX activity


negative regulation of exonuclease IX activity


down-regulation of exonuclease IX activity

downregulation of exonuclease IX activity

down regulation of exonuclease IX activity


activation of mesodermal cell differentiation

activation of mesoderm cell differentiation


inhibition of mesodermal cell differentiation

inhibition of mesoderm cell differentiation


activation of double-stranded telomeric DNA binding


inhibition of double-stranded telomeric DNA binding


activation of protection from non-homologous end joining at telomere


activation of protection from NHEJ-mediated telomere fusion


inhibition of protection from non-homologous end joining at telomere


inhibition of protection from NHEJ-mediated telomere fusion


SCF complex substrate recognition subunit binding


microtubule end of neurotubule of post-anaphase microtubule array

microtubule end of neurotubule of post-anaphase array


neurotubule of post-anaphase microtubule array


activation of L-citrulline:L-aspartate ligase (AMP-forming)


activation of citrulline--aspartate ligase activity


activation of arginosuccinate synthetase activity


activation of argininosuccinic acid synthetase activity


activation of argininosuccinate synthetase activity


activation of argininosuccinate synthase activity


activation of arginine succinate synthetase activity


activation of endosome to plasma membrane protein transport


inhibition of endosome to plasma membrane protein transport


regulation of nuclear mRNA cis splicing, via U2-type spliceosome


activation of trypanothione biosynthetic process


activation of trypanothione biosynthesis


inhibition of trypanothione biosynthetic process


inhibition of trypanothione biosynthesis


activation of inhibitory synapse formation


activation of inhibitory synapse assembly


inhibition of inhibitory synapse formation

inhibition of inhibitory synapse assembly


activation of phosphatidic acid synthesis


activation of phosphatidic acid formation


activation of phosphatidic acid biosynthetic process


activation of phosphatidic acid biosynthesis


activation of phosphatidic acid anabolism


inhibition of phosphatidic acid synthesis


inhibition of phosphatidic acid formation


inhibition of phosphatidic acid biosynthetic process


inhibition of phosphatidic acid biosynthesis


inhibition of phosphatidic acid anabolism


up-regulation of diacylglycerol:ATP kinase activity

upregulation of diacylglycerol:ATP kinase activity

up regulation of diacylglycerol:ATP kinase activity


upregulation of CTP:diacylglycerol kinase activity

up-regulation of CTP:diacylglycerol kinase activity

up regulation of CTP:diacylglycerol kinase activity


up-regulation of ATP:diacylglycerol phosphotransferase activity

upregulation of ATP:diacylglycerol phosphotransferase activity

up regulation of ATP:diacylglycerol phosphotransferase activity


upregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity

up-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity

up regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity


positive regulation of diacylglycerol:ATP kinase activity


positive regulation of CTP:diacylglycerol kinase activity


positive regulation of ATP:diacylglycerol phosphotransferase activity


positive regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity


activation of sn-1,2-diacylglycerol kinase activity


activation of diglyceride kinase activity


activation of diacylglycerol:ATP kinase activity


activation of diacylglycerol kinase activity


activation of CTP:diacylglycerol kinase activity


activation of ATP:diacylglycerol phosphotransferase activity


activation of ATP:1,2-diacylglycerol 3-phosphotransferase activity


activation of arachidonoyl-specific diacylglycerol kinase activity


activation of 1,2-diacylglycerol kinase activity


activation of 1,2-diacylglycerol kinase (phosphorylating)


negative regulation of diacylglycerol:ATP kinase activity


negative regulation of CTP:diacylglycerol kinase activity


negative regulation of ATP:diacylglycerol phosphotransferase activity


negative regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity


inhibition of sn-1,2-diacylglycerol kinase activity


inhibition of diglyceride kinase activity


inhibition of diacylglycerol:ATP kinase activity


inhibition of diacylglycerol kinase activity


inhibition of CTP:diacylglycerol kinase activity


inhibition of ATP:diacylglycerol phosphotransferase activity


inhibition of ATP:1,2-diacylglycerol 3-phosphotransferase activity


inhibition of arachidonoyl-specific diacylglycerol kinase activity


inhibition of 1,2-diacylglycerol kinase activity


inhibition of 1,2-diacylglycerol kinase (phosphorylating)


downregulation of diacylglycerol:ATP kinase activity

down-regulation of diacylglycerol:ATP kinase activity

down regulation of diacylglycerol:ATP kinase activity


downregulation of CTP:diacylglycerol kinase activity

down-regulation of CTP:diacylglycerol kinase activity

down regulation of CTP:diacylglycerol kinase activity


down-regulation of ATP:diacylglycerol phosphotransferase activity

downregulation of ATP:diacylglycerol phosphotransferase activity

down regulation of ATP:diacylglycerol phosphotransferase activity


down-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity

downregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity

down regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity


regulation of diacylglycerol:ATP kinase activity


regulation of CTP:diacylglycerol kinase activity


regulation of ATP:diacylglycerol phosphotransferase activity


regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity


The disaggregation of a peroxisome into its constituent components. [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie]


activation of innate immunity memory response


inhibition of innate immunity memory response


activation of adaptive immune effector response


inhibition of adaptive immune effector response


activation of adaptive immune memory response


inhibition of adaptive immune memory response


up regulation of lysosome organization and biogenesis

up-regulation of lysosome organization and biogenesis

upregulation of lysosome organization and biogenesis

positive regulation of lysosome organization and biogenesis


activation of lysosome organization and biogenesis


downregulation of lysosome organization and biogenesis

down-regulation of lysosome organization and biogenesis

negative regulation of lysosome organization and biogenesis

down regulation of lysosome organization and biogenesis


inhibition of lysosome organization and biogenesis


regulation of lysosome organization and biogenesis


activation of protein localization to endosome


activation of protein localization in endosome

activation of protein localisation in endosome


inhibition of protein localization to endosome


inhibition of protein localization in endosome

inhibition of protein localisation in endosome


activation of calcium ion import across plasma membrane


activation of telomerase RNA reverse transcriptase activity


inhibition of telomerase RNA reverse transcriptase activity


activation of artery smooth muscle contraction


inhibition of artery smooth muscle contraction


activation of arteriogenesis
activation of artery morphogenesis


inhibition of arteriogenesis
inhibition of artery morphogenesis


activation of Facilitates chromatin transcription complex assembly


activation of Facilitates chromatin transcription complex formation


inhibition of Facilitates chromatin transcription complex assembly


inhibition of Facilitates chromatin transcription complex formation


activation of mitochondrial mRNA catabolic process


inhibition of mitochondrial mRNA catabolic process


activation of RNA polymerase II regulatory region sequence-specific DNA binding


activation of serotonin biosynthetic process


inhibition of serotonin biosynthetic process


activation of alpha-1,3-fucosyltransferase activity

activation of alpha-(1->3)-fucosyltransferase activity

activation of alpha-(1,3)-fucosyltransferase activity

activation of alpha(1,3)-fucosyltransferase activity


inhibition of alpha-(1->3)-fucosyltransferase activity

inhibition of alpha-(1,3)-fucosyltransferase activity

inhibition of alpha-1,3-fucosyltransferase activity

inhibition of alpha(1,3)-fucosyltransferase activity


activation of developmental vegetative growth


inhibition of developmental vegetative growth


activation of smooth muscle cell-matrix adhesion


activation of presynaptic terminal assembly


inhibition of presynaptic terminal assembly


activation of maintenance of permeability of blood-brain barrier

activation of maintenance of permeability of BBB


inhibition of maintenance of permeability of blood-brain barrier

inhibition of maintenance of permeability of BBB


upregulation of receptor-mediated endocytosis of LDL

up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport

upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport

up regulation of receptor-mediated endocytosis of LDL

up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport

up-regulation of receptor-mediated endocytosis of LDL

positive regulation of receptor-mediated endocytosis of LDL

OBSOLETE. Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640]


up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport

upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport

up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport


upregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport

up-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport

up regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport


positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport


positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport


positive regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport


activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport


activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport


activation of receptor-mediated endocytosis of LDL


activation of receptor-mediated endocytosis involved in intracellular cholesterol transport


activation of receptor-mediated endocytosis involved in cholesterol transport


negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport


negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport


down-regulation of receptor-mediated endocytosis of LDL

down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport

downregulation of receptor-mediated endocytosis of LDL

down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport

negative regulation of receptor-mediated endocytosis of LDL

downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport

down regulation of receptor-mediated endocytosis of LDL

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640]


negative regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport


inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport


inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport


inhibition of receptor-mediated endocytosis of LDL


inhibition of receptor-mediated endocytosis involved in intracellular cholesterol transport


inhibition of receptor-mediated endocytosis involved in cholesterol transport


down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport

downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport

down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport


down-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport

downregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport

down regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport


regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport


regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport


regulation of receptor-mediated endocytosis of LDL

OBSOLETE. Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport. [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640]


regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport


activation of low-density lipoprotein receptor activity


inhibition of low-density lipoprotein receptor activity


activation of low-density lipoprotein receptor binding


activation of low-density lipoprotein particle receptor binding


inhibition of low-density lipoprotein receptor binding


inhibition of low-density lipoprotein particle receptor binding


activation of optical nerve axon regeneration


inhibition of optical nerve axon regeneration


activation of L-arginine import across plasma membrane


up-regulation of outer hair cell apoptosis

upregulation of outer hair cell apoptosis

up regulation of outer hair cell apoptosis


upregulation of cochlear outer hair cell apoptosis

up-regulation of cochlear outer hair cell apoptosis

up regulation of cochlear outer hair cell apoptosis


positive regulation of outer hair cell apoptosis


positive regulation of cochlear outer hair cell apoptosis


activation of outer hair cell apoptotic process


activation of cochlear outer hair cell apoptotic process

activation of cochlear outer hair cell apoptosis


negative regulation of outer hair cell apoptosis


negative regulation of cochlear outer hair cell apoptosis


inhibition of outer hair cell apoptotic process


inhibition of cochlear outer hair cell apoptotic process


inhibition of cochlear outer hair cell apoptosis


down-regulation of outer hair cell apoptosis

downregulation of outer hair cell apoptosis

down regulation of outer hair cell apoptosis


downregulation of cochlear outer hair cell apoptosis

down-regulation of cochlear outer hair cell apoptosis

down regulation of cochlear outer hair cell apoptosis


regulation of cochlear outer hair cell apoptosis


activation of low-density lipoprotein particle clearance


activation of receptor tyrosine-protein kinase erbB-3 signaling pathway


inhibition of receptor tyrosine-protein kinase erbB-3 signaling pathway


upregulation of ferrichrome biosynthetic process, peptide modification

up-regulation of ferrichrome biosynthetic process, peptide modification

up regulation of ferrichrome biosynthetic process, peptide modification


up-regulation of ferrichrome biosynthetic process, peptide formation

upregulation of ferrichrome biosynthetic process, peptide formation

up regulation of ferrichrome biosynthetic process, peptide formation


positive regulation of ferrichrome biosynthetic process, peptide modification


positive regulation of ferrichrome biosynthetic process, peptide formation


activation of ferrichrome biosynthetic process, peptide modification


activation of ferrichrome biosynthetic process, peptide formation


activation of ferrichrome biosynthetic process


negative regulation of ferrichrome biosynthetic process, peptide modification


negative regulation of ferrichrome biosynthetic process, peptide formation


inhibition of ferrichrome biosynthetic process, peptide modification


inhibition of ferrichrome biosynthetic process, peptide formation


inhibition of ferrichrome biosynthetic process


downregulation of ferrichrome biosynthetic process, peptide modification

down-regulation of ferrichrome biosynthetic process, peptide modification

down regulation of ferrichrome biosynthetic process, peptide modification


downregulation of ferrichrome biosynthetic process, peptide formation

down-regulation of ferrichrome biosynthetic process, peptide formation

down regulation of ferrichrome biosynthetic process, peptide formation


regulation of ferrichrome biosynthetic process, peptide modification


regulation of ferrichrome biosynthetic process, peptide formation


activation of vascular endothelial cell proliferation


inhibition of vascular endothelial cell proliferation


up-regulation of kinetochore formation
upregulation of kinetochore formation


upregulation of chromosome-kinetochore attachment

up-regulation of chromosome-kinetochore attachment

up regulation of chromosome-kinetochore attachment


upregulation of centromere/kinetochore complex maturation

up-regulation of centromere and kinetochore complex maturation

up-regulation of centromere/kinetochore complex maturation

up regulation of centromere/kinetochore complex maturation

upregulation of centromere and kinetochore complex maturation

up regulation of centromere and kinetochore complex maturation


positive regulation of kinetochore formation


positive regulation of chromosome-kinetochore attachment


positive regulation of centromere/kinetochore complex maturation

positive regulation of centromere and kinetochore complex maturation


activation of chromosome-kinetochore attachment


activation of centromere/kinetochore complex maturation

activation of centromere and kinetochore complex maturation


negative regulation of kinetochore formation


negative regulation of chromosome-kinetochore attachment


negative regulation of centromere/kinetochore complex maturation

negative regulation of centromere and kinetochore complex maturation


inhibition of chromosome-kinetochore attachment


inhibition of centromere/kinetochore complex maturation

inhibition of centromere and kinetochore complex maturation


down-regulation of kinetochore formation

down regulation of kinetochore formation


down-regulation of chromosome-kinetochore attachment

downregulation of chromosome-kinetochore attachment

down regulation of chromosome-kinetochore attachment


downregulation of centromere and kinetochore complex maturation

down regulation of centromere/kinetochore complex maturation

down-regulation of centromere and kinetochore complex maturation

downregulation of centromere/kinetochore complex maturation

down-regulation of centromere/kinetochore complex maturation

down regulation of centromere and kinetochore complex maturation


activation of mitotic nuclear envelope disassembly


activation of mitotic nuclear envelope degradation


activation of mitotic nuclear envelope catabolism


activation of mitotic nuclear envelope breakdown


inhibition of mitotic nuclear envelope disassembly


inhibition of mitotic nuclear envelope degradation


inhibition of mitotic nuclear envelope catabolism


inhibition of mitotic nuclear envelope breakdown


activation of patterning of blood vessels


activation of branching involved in blood vessel morphogenesis


inhibition of patterning of blood vessels


inhibition of branching involved in blood vessel morphogenesis


activation of protein localization to endoplasmic reticulum


activation of protein localization in endoplasmic reticulum

activation of protein localization in ER

activation of protein localisation in endoplasmic reticulum


inhibition of protein localization to endoplasmic reticulum


inhibition of protein localization in ER

inhibition of protein localization in endoplasmic reticulum

inhibition of protein localisation in endoplasmic reticulum


activation of eukaryotic translation initiation factor 4F complex assembly


inhibition of eukaryotic translation initiation factor 4F complex assembly


positive regulation of L-leucine import into cell


activation of L-leucine import into cell


negative regulation of L-leucine import into cell


inhibition of L-leucine import into cell


downregulation of L-leucine import into cell

down-regulation of L-leucine import into cell

down regulation of L-leucine import into cell


regulation of L-leucine import into cell


inhibition of protein self-ubiquitinylation


inhibition of protein self-ubiquitination


inhibition of protein autoubiquitinylation


inhibition of protein autoubiquitination


inhibition of protein auto-ubiquitinylation


inhibition of protein auto-ubiquitination


up regulation of pre-synaptic active zone component formation

up-regulation of pre-synaptic active zone component assembly

upregulation of pre-synaptic active zone component formation

up-regulation of pre-synaptic active zone component formation

upregulation of pre-synaptic active zone component assembly

up regulation of pre-synaptic active zone component assembly


positive regulation of pre-synaptic active zone component formation

positive regulation of pre-synaptic active zone component assembly


activation of presynaptic active zone assembly

activation of presynaptic active zone formation

activation of pre-synaptic active zone formation

activation of pre-synaptic active zone assembly


activation of pre-synaptic active zone component formation

activation of pre-synaptic active zone component assembly


negative regulation of pre-synaptic active zone component formation

negative regulation of pre-synaptic active zone component assembly


inhibition of presynaptic active zone formation

inhibition of presynaptic active zone assembly

inhibition of pre-synaptic active zone formation

inhibition of pre-synaptic active zone assembly


inhibition of pre-synaptic active zone component formation

inhibition of pre-synaptic active zone component assembly


down regulation of pre-synaptic active zone component formation

downregulation of pre-synaptic active zone component formation

down-regulation of pre-synaptic active zone component assembly

downregulation of pre-synaptic active zone component assembly

down-regulation of pre-synaptic active zone component formation

down regulation of pre-synaptic active zone component assembly


regulation of pre-synaptic active zone component formation

regulation of pre-synaptic active zone component assembly


activation of short-term synaptic potentiation


inhibition of short-term synaptic potentiation


upregulation of myosin II polymerization

up-regulation of myosin II polymerization

up regulation of myosin II polymerization


positive regulation of myosin II polymerization


activation of myosin II filament assembly


negative regulation of myosin II polymerization


inhibition of myosin II filament assembly


down-regulation of myosin II polymerization

downregulation of myosin II polymerization

down regulation of myosin II polymerization


upregulation of nodal cilium formation
up-regulation of nodal cilium formation


up-regulation of nodal cilium assembly
upregulation of nodal cilium assembly


upregulation of motile primary cilium formation

upregulation of motile primary cilia formation

up-regulation of motile primary cilia formation

up regulation of motile primary cilium formation

up-regulation of motile primary cilium formation

up regulation of motile primary cilia formation


up-regulation of motile primary cilium assembly

upregulation of motile primary cilia assembly

up regulation of motile primary cilium assembly

up-regulation of motile primary cilia assembly

upregulation of motile primary cilium assembly

up regulation of motile primary cilia assembly


positive regulation of nodal cilium formation


positive regulation of nodal cilium assembly


positive regulation of motile primary cilium formation

positive regulation of motile primary cilia formation


positive regulation of motile primary cilium assembly

positive regulation of motile primary cilia assembly


activation of motile primary cilium formation

activation of motile primary cilia formation


activation of motile primary cilium assembly

activation of motile primary cilia assembly


negative regulation of nodal cilium formation

negative regulation of nodal cilium assembly


negative regulation of motile primary cilium formation

negative regulation of motile primary cilia formation


negative regulation of motile primary cilium assembly

negative regulation of motile primary cilia assembly


inhibition of motile primary cilium formation

inhibition of motile primary cilia formation


inhibition of motile primary cilium assembly

inhibition of motile primary cilia assembly


downregulation of nodal cilium formation

down-regulation of nodal cilium formation

down regulation of nodal cilium formation


down-regulation of nodal cilium assembly

down regulation of nodal cilium assembly


downregulation of motile primary cilium formation

downregulation of motile primary cilia formation

down regulation of motile primary cilium formation

down-regulation of motile primary cilium formation

down-regulation of motile primary cilia formation

down regulation of motile primary cilia formation


regulation of motile primary cilium formation

regulation of motile primary cilia formation


regulation of motile primary cilium assembly

regulation of motile primary cilia assembly


inhibition of G quartet DNA binding
inhibition of G-quadruplex DNA binding
inhibition of G-DNA binding
inhibition of G-quartet DNA binding


regulation of G-DNA binding
regulation of quadruplex DNA binding
regulation of G quartet DNA binding
regulation of tetraplex DNA binding
regulation of G quartet binding
regulation of G quadruplex DNA binding
regulation of G-quartet DNA binding
regulation of G-quartet binding

Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding. [GO_REF:0000059, GOC:TermGenie, PMID:26503245]


activation of branching morphogenesis of a nerve


activation of sensory neuron axon guidance


inhibition of sensory neuron axon guidance


activation of anterior/posterior axon pathfinding


activation of anterior/posterior axon guidance

activation of anterior-posterior axon guidance


inhibition of anterior/posterior axon pathfinding


inhibition of anterior/posterior axon guidance

inhibition of anterior-posterior axon guidance


activation of L-glutamine synthetase activity


activation of L-glutamate:ammonia ligase (ADP-forming)


activation of glutamylhydroxamic synthetase activity


activation of glutamine synthetase activity


activation of glutamate-ammonia ligase activity


inhibition of L-glutamine synthetase activity


inhibition of L-glutamate:ammonia ligase (ADP-forming)


inhibition of glutamylhydroxamic synthetase activity


inhibition of glutamine synthetase activity


inhibition of glutamate-ammonia ligase activity


activation of protein localization to membrane


activation of protein localization in membrane

activation of protein localisation in membrane


inhibition of protein localization to membrane


inhibition of protein localization in membrane

inhibition of protein localisation in membrane


frizzled-1 receptor signaling pathway involved in stem cell proliferation


activation of histone lysine H3 K79 dimethylation


activation of histone H3-K79 dimethylation

activation of histone H3 K79 dimethylation


inhibition of histone lysine H3 K79 dimethylation


inhibition of histone H3-K79 dimethylation

inhibition of histone H3 K79 dimethylation


activation of clathrin-coated pit formation


activation of clathrin-coated pit assembly


inhibition of clathrin-coated pit formation

inhibition of clathrin-coated pit assembly


activation of G-quadruplex DNA unwinding


inhibition of G-quadruplex DNA unwinding


up-regulation of VSMC apoptosis
upregulation of VSMC apoptosis


upregulation of vascular smooth muscle cell apoptosis

up-regulation of vascular smooth muscle cell apoptosis

up regulation of vascular smooth muscle cell apoptosis


upregulation of vascular associated smooth muscle cell apoptosis

up-regulation of vascular associated smooth muscle cell apoptosis

up regulation of vascular associated smooth muscle cell apoptosis


positive regulation of vascular smooth muscle cell apoptosis


positive regulation of vascular associated smooth muscle cell apoptosis


activation of vascular smooth muscle cell apoptotic process


activation of vascular smooth muscle cell apoptosis


activation of vascular associated smooth muscle cell apoptotic process

activation of vascular associated smooth muscle cell apoptosis


negative regulation of vascular smooth muscle cell apoptosis


negative regulation of vascular associated smooth muscle cell apoptosis


inhibition of vascular associated smooth muscle cell apoptotic process


inhibition of vascular associated smooth muscle cell apoptosis


inhibition of vascular smooth muscle cell apoptotic process

inhibition of vascular smooth muscle cell apoptosis


downregulation of vascular associated smooth muscle cell apoptosis

down-regulation of vascular associated smooth muscle cell apoptosis

down regulation of vascular associated smooth muscle cell apoptosis


down-regulation of vascular smooth muscle cell apoptosis

downregulation of vascular smooth muscle cell apoptosis

down regulation of vascular smooth muscle cell apoptosis


regulation of vascular smooth muscle cell apoptosis


regulation of vascular associated smooth muscle cell apoptosis


activation of lymphoid progenitor cell differentiation


inhibition of lymphoid progenitor cell differentiation


activation of myeloid progenitor cell differentiation


inhibition of myeloid progenitor cell differentiation


activation of Fcgamma receptor-mediated phagocytosis


activation of Fc-gamma receptor signalling pathway involved in phagocytosis

activation of Fc-gamma receptor signaling pathway involved in phagocytosis


activation of Fc gamma receptor-dependent phagocytosis


inhibition of Fcgamma receptor-mediated phagocytosis


inhibition of Fc-gamma receptor signalling pathway involved in phagocytosis

inhibition of Fc-gamma receptor signaling pathway involved in phagocytosis


inhibition of Fc gamma receptor-dependent phagocytosis


activation of mitochondrial ATP synthesis coupled electron transport


inhibition of mitochondrial ATP synthesis coupled electron transport


regulation of organelle ATP synthesis coupled electron transport


regulation of mitochondrial electron transport


activation of histone H3-K4 trimethylation


inhibition of histone H3-K4 trimethylation


positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling


activation of retrograde trans-synaptic signaling by neuropeptide


negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling


inhibition of retrograde trans-synaptic signaling by neuropeptide


inhibition of neuropeptide-mediated retrograde trans-synaptic signaling


regulation of neuropeptide-mediated retrograde trans-synaptic signaling


signal transmission via intracellular cascade involved in up-regulation of cell growth

signal transmission via intracellular cascade involved in upregulation of cell growth

signal transmission via intracellular cascade involved in up regulation of cell growth


signal transmission via intracellular cascade involved in stimulation of cell growth


signal transmission via intracellular cascade involved in positive regulation of cell growth


signal transmission via intracellular cascade involved in activation of cell growth


signal transduction via intracellular signaling cascade involved in upregulation of cell growth

signal transduction via intracellular signaling cascade involved in up-regulation of cell growth

signal transduction via intracellular signaling cascade involved in up regulation of cell growth


signal transduction via intracellular signaling cascade involved in stimulation of cell growth


signal transduction via intracellular signaling cascade involved in positive regulation of cell growth


signal transduction via intracellular signaling cascade involved in activation of cell growth


protein kinase cascade involved in upregulation of cell growth

protein kinase cascade involved in up-regulation of cell growth

protein kinase cascade involved in up regulation of cell growth


protein kinase cascade involved in stimulation of cell growth


protein kinase cascade involved in positive regulation of cell growth


protein kinase cascade involved in activation of cell growth


intracellular signaling pathway involved in up-regulation of cell growth

intracellular signaling pathway involved in upregulation of cell growth

intracellular signaling pathway involved in up regulation of cell growth


intracellular signaling pathway involved in stimulation of cell growth


intracellular signaling pathway involved in positive regulation of cell growth


intracellular signaling pathway involved in activation of cell growth


intracellular signaling chain involved in stimulation of cell growth


intracellular signaling chain involved in activation of cell growth


intracellular signaling cascade involved in upregulation of cell growth

intracellular signaling cascade involved in up-regulation of cell growth

intracellular signaling cascade involved in up regulation of cell growth


intracellular signaling cascade involved in stimulation of cell growth


intracellular signaling cascade involved in positive regulation of cell growth


intracellular signaling cascade involved in activation of cell growth


intracellular signal transduction pathway involved in up-regulation of cell growth

intracellular signal transduction pathway involved in upregulation of cell growth

intracellular signal transduction pathway involved in up regulation of cell growth


intracellular signal transduction pathway involved in stimulation of cell growth


intracellular signal transduction pathway involved in positive regulation of cell growth


intracellular signal transduction pathway involved in activation of cell growth


intracellular signal transduction involved in stimulation of cell growth


intracellular signal transduction involved in activation of cell growth


intracellular protein kinase cascade involved in upregulation of cell growth

intracellular protein kinase cascade involved in up-regulation of cell growth

intracellular protein kinase cascade involved in up regulation of cell growth


intracellular protein kinase cascade involved in stimulation of cell growth


intracellular protein kinase cascade involved in positive regulation of cell growth


intracellular protein kinase cascade involved in activation of cell growth


upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production

up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production

up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production


up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation

upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation

up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation


up-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis

upregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis

up regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis


upregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation

up-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation

up regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation


up-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate

upregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate

up regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate


positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production


positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation


positive regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis


positive regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation


positive regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate


positive regulation of midbrain dopaminergic neuron differentiation by positive regulation of Wnt signaling


activation of Wnt-mediated midbrain DA neuron differentiation


activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production


activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation


activation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis


activation of Wnt-activated signaling pathway involved in mDA neuron differentiation


activation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate


activation of Wnt signaling pathway involved in midbrain dopaminergic neuron production


activation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation


activation of Wnt signaling pathway involved in midbrain DA neurogenesis


activation of Wnt signaling pathway involved in mDA neuron differentiation


activation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate


activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production

activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production


activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation

activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation


activation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis

activation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis


activation of Wnt receptor signalling pathway involved in mDA neuron differentiation

activation of Wnt receptor signaling pathway involved in mDA neuron differentiation


activation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate

activation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate


activation of Wingless signalling pathway involved in midbrain dopaminergic neuron production

activation of Wingless signaling pathway involved in midbrain dopaminergic neuron production


activation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation

activation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation


activation of Wingless signalling pathway involved in midbrain DA neurogenesis

activation of Wingless signaling pathway involved in midbrain DA neurogenesis


activation of Wingless signalling pathway involved in mDA neuron differentiation

activation of Wingless signaling pathway involved in mDA neuron differentiation


activation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate

activation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate


activation of Wg signalling pathway involved in midbrain dopaminergic neuron production

activation of Wg signaling pathway involved in midbrain dopaminergic neuron production


activation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation

activation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation


activation of Wg signalling pathway involved in midbrain DA neurogenesis

activation of Wg signaling pathway involved in midbrain DA neurogenesis


activation of Wg signalling pathway involved in mDA neuron differentiation

activation of Wg signaling pathway involved in mDA neuron differentiation


activation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate

activation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate


activation of frizzled signalling pathway involved in midbrain dopaminergic neuron production

activation of frizzled signaling pathway involved in midbrain dopaminergic neuron production


activation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation

activation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation


activation of frizzled signalling pathway involved in midbrain DA neurogenesis

activation of frizzled signaling pathway involved in midbrain DA neurogenesis


activation of frizzled signalling pathway involved in mDA neuron differentiation

activation of frizzled signaling pathway involved in mDA neuron differentiation


activation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate

activation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate


negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production


negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation


negative regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis


negative regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation


negative regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate


negative regulation of midbrain dopaminergic neuron differentiation by negative regulation of Wnt signaling


inhibition of Wnt-mediated midbrain DA neuron differentiation


inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production


inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation


inhibition of Wnt-activated signaling pathway involved in midbrain DA neurogenesis


inhibition of Wnt-activated signaling pathway involved in mDA neuron differentiation


inhibition of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate


inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron production


inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation


inhibition of Wnt signaling pathway involved in midbrain DA neurogenesis


inhibition of Wnt signaling pathway involved in mDA neuron differentiation


inhibition of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate


inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production

inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production


inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation

inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation