regulation of chaperone-mediated protein complex assembly

Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of chaperone-mediated protein complex assembly

Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex. [GOC:BHF, GOC:dph, GOC:tb]


regulation of protein kinase C signaling cascade

regulation of protein kinase C signalling cascade

Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. [GOC:dph, GOC:tb]


positive regulation of protein kinase C signalling cascade

positive regulation of protein kinase C signaling cascade

Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. [GOC:dph, GOC:tb]


negative regulation of protein kinase C signaling cascade

negative regulation of protein kinase C signalling cascade

Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. [GOC:dph, GOC:tb]


regulation of gene-specific transcription elongation from RNA polymerase II promoter


positive regulation of gene-specific transcription elongation from RNA polymerase II promoter


negative regulation of gene-specific transcription elongation from RNA polymerase II promoter


The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. [GOC:BHF, GOC:dph, GOC:tb]


Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of tubulin deacetylation

Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of deacetylase activity

Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. [GOC:BHF, GOC:dph, GOC:tb]


regulation of cell migration involved in sprouting angiogenesis

Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]


positive regulation of cell migration involved in sprouting angiogenesis

Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]


negative regulation of cell migration involved in sprouting angiogenesis

Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]


regulation of chromatin silencing at centromere

regulation of pericentric heterochromatin assembly

Any process that modulates the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin. [GOC:dph, GOC:tb]


positive regulation of chromatin silencing at centromere

positive regulation of pericentric heterochromatin assembly

Any process that increases the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin. [GOC:dph, GOC:tb]


regulation of chromatin silencing at silent mating-type cassette

regulation of silent mating-type cassette heterochromatin assembly

Any process that modulates the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. [GOC:dph, GOC:tb]


positive regulation of chromatin silencing at silent mating-type cassette

positive regulation of silent mating-type cassette heterochromatin assembly

Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin. [GOC:dph, GOC:tb]


regulation of chlorophyll metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll. [GOC:dph, GOC:tb]


The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed. [GOC:dph, GOC:sdb_2009, GOC:tb]


The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem. [GOC:dph, GOC:sdb_2009, GOC:tb]


Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed. [GOC:dph, GOC:sdb_2009, GOC:tb]


regulation of trehalose metabolic process

Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi. [GOC:dph, GOC:tb]


positive regulation of microtubule nucleation

Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. [GOC:dph, GOC:tb]


Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. [GOC:dph, GOC:tb]


Any process that modulates the size of an anatomical structure. [GOC:dph, GOC:tb]


Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus. [GOC:dph, GOC:tb]


positive regulation of cell cycle process

Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. [GOC:dph, GOC:tb]


positive regulation of ribosome biogenesis

Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. [GOC:dph, GOC:tb]


negative regulation of ribosome biogenesis

Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. [GOC:dph, GOC:tb]


positive regulation of protein homodimerization activity

Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer. [GOC:dph, GOC:tb]


negative regulation of protein homodimerization activity

Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer. [GOC:dph, GOC:tb]


A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. [GOC:BHF, GOC:rl]


The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:BHF, GOC:dph, GOC:tb]


smooth muscle derived foam cell differentiation

The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:BHF, GOC:dph, GOC:tb]


translation regulator activity, nucleic acid binding

Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome. [GOC:dph, GOC:tb, GOC:vw]


positive regulation of MAPKKK cascade by fibroblast growth factor receptor signalling pathway

positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade. [GOC:dph, GOC:tb]


regulation of heart induction by regulation of canonical Wnt receptor signaling pathway

regulation of heart induction by regulation of canonical Wnt-activated signaling pathway

regulation of heart induction by regulation of canonical Wnt receptor signalling pathway

regulation of heart induction by regulation of canonical Wnt signaling pathway

Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:mtg_heart]


positive regulation of heart induction by negative regulation of canonical Wnt receptor signalling pathway

positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway

positive regulation of heart induction by negative regulation of canonical Wnt-activated signaling pathway

positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway

Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:mtg_heart, PMID:16860783]


Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of inclusion body assembly

Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. [GOC:BHF, GOC:dph, GOC:tb]


Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of protein deubiquitination

Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein. [GOC:BHF, GOC:dph, GOC:tb]


Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. [GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


negative regulation of canonical Wnt receptor signaling pathway

negative regulation of canonical Wnt-activated signaling pathway

negative regulation of canonical Wnt receptor signalling pathway

negative regulation of Wnt receptor signaling pathway through beta-catenin

negative regulation of canonical Wnt signaling pathway

Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:dph, GOC:tb]


positive regulation of extracellular matrix disassembly

Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. [GOC:dph, GOC:tb]


regulation of transmembrane receptor protein serine/threonine kinase signalling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. [GOC:dph, GOC:tb]


regulation of fungal-type cell wall beta-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells. [GOC:dph, GOC:tb]


metanephric cap mesenchymal cell proliferation involved in metanephros development

The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. [GOC:dph, GOC:tb, GOC:yaf, PMID:19161241]


regulation of metanephric cap mesenchymal cell proliferation

Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. [GOC:dph, GOC:tb, GOC:yaf]


positive regulation of metanephric cap mesenchymal cell proliferation

Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip. [GOC:dph, GOC:tb, GOC:yaf]


regulation of decapentaplegic receptor signalling pathway

regulation of decapentaplegic signaling pathway

regulation of decapentaplegic receptor signaling pathway


positive regulation of decapentaplegic signaling pathway


negative regulation of decapentaplegic receptor signalling pathway

negative regulation of decapentaplegic signaling pathway

negative regulation of decapentaplegic receptor signaling pathway


positive regulation of transmembrane receptor protein serine/threonine kinase signalling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. [GOC:dph, GOC:tb]


negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. [GOC:dph, GOC:tb]


The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. [GOC:dph, GOC:tb]


The process in which the cochlea is generated and organized. [GOC:dph, GOC:tb]


The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin. [GOC:dph, GOC:tb]


The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure. [GOC:dph, GOC:tb]


The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell. [GOC:dph, GOC:tb]


regulation of high-density lipoprotein particle assembly

Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. [GOC:dph, GOC:tb]


positive regulation of high-density lipoprotein particle assembly

Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. [GOC:BHF, GOC:dph, GOC:tb]


regulation of cell-substrate junction assembly

Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate. [GOC:dph, GOC:tb]


cargo selection into COPII-coated vesicle

The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi. [GOC:ascb_2009, GOC:dph, GOC:lb, GOC:tb]


Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released. [GOC:ascb_2009, GOC:dph, GOC:tb]


The process in which COPII vesicle coat proteins are disassembled, and released. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis

The GTP hydrolysis process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. [GOC:ascb_2009, GOC:dph, GOC:tb]


The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle. [GOC:ascb_2009, GOC:dph, GOC:tb]


The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule. [GOC:ascb_2009, GOC:dph, GOC:tb]


endosome to lysosome transport of low-density lipoprotein particle

The directed movement of low-density lipoprotein particle from endosomes to lysosomes. [GOC:ascb_2009, GOC:dph, GOC:tb]


receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport


The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles. [GOC:ascb_2009, GOC:dph, GOC:tb]


lysosome to endoplasmic reticulum cholesterol transport

The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum. [GOC:mah]


low-density lipoprotein particle disassembly involved in cholesterol transport

The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport. [GOC:ascb_2009, GOC:dph, GOC:tb]


cholesterol ester hydrolysis involved in cholesterol transport

The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport. [GOC:ascb_2009, GOC:dph, GOC:tb]


The polysaccharide-based coating on the inner side of a lysosomal membrane. It may be involved in protecting the membrane from digestion by lysosomal enzymes. [GOC:ascb_2009, GOC:dph, GOC:krc, GOC:tb, PMID:10521503, PMID:22809326, PMID:29367433]


The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule. [GOC:ascb_2009, GOC:dph, GOC:tb]


cell-cell adhesion involved in synapse maturation

The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation. [GOC:ascb_2009, GOC:dph, GOC:tb]


protein complex assembly involved in synapse maturation


positive regulation of synapse maturation by synaptic transmission

Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state. [GOC:ascb_2009, GOC:dph, GOC:tb]


positive regulation of synapse maturation

Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state. [GOC:ascb_2009, GOC:dph, GOC:tb]


The process in which the population of cells that make up a tissue undergo directed movement. [GOC:ascb_2009, GOC:dph, GOC:tb]


The process in which the population of cells that make up a mesenchyme undergo directed movement. [GOC:ascb_2009, GOC:dph, GOC:tb]


The process in which the population of cells that make up an epithelium undergo directed movement. [GOC:ascb_2009, GOC:dph, GOC:tb]


The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm. [GOC:ascb_2009, GOC:dph, GOC:tb]


cell migration involved in mesendoderm migration

The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue. [GOC:ascb_2009, GOC:dph, GOC:tb]


The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments. [GOC:ascb_2009, GOC:dph, GOC:tb]


The attachment of an epithelial cell to another epithelial cell via adhesion molecules. [GOC:ascb_2009, GOC:dph, GOC:tb]


epithelial cell-cell adhesion involved in epithelium migration

The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of actin cytoskeleton organisation by cell-cell adhesion

regulation of actin cytoskeleton organization by cell-cell adhesion

Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. [GOC:ascb_2009, GOC:dph, GOC:tb]


A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. [GOC:ascb_2009, GOC:dph, GOC:tb]


positive regulation of mitochondrial division

positive regulation of mitochondrial fission

Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. [GOC:ascb_2009, GOC:dph, GOC:tb]


A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined. [GOC:ascb_2009, GOC:dph, GOC:tb]


A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined. [GOC:ascb_2009, GOC:dph, GOC:tb]


A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes. [GOC:ascb_2009, GOC:dph, GOC:tb]


membrane fission involved in mitochondrial fission

A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission. [GOC:ascb_2009, GOC:dph, GOC:tb]


establishment of protein localisation in membrane

establishment of protein localization in membrane

establishment of protein localization to membrane

The directed movement of a protein to a specific location in a membrane. [GOC:ascb_2009, GOC:dph, GOC:tb]


establishment of protein localisation in mitochondrial membrane

establishment of protein localization in mitochondrial membrane

establishment of protein localization to mitochondrial membrane

The directed movement of a protein to a specific location in the mitochondrial membrane. [GOC:ascb_2009, GOC:dph, GOC:tb]


establishment of protein localization in mitochondrial membrane involved in mitochondrial fission

establishment of protein localisation in mitochondrial membrane involved in mitochondrial fission

establishment of protein localization to mitochondrial membrane involved in mitochondrial fission

The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of sphingolipid biosynthetic process

Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). [GOC:ascb_2009, GOC:dph, GOC:tb]


positive regulation of sphingolipid biosynthetic process

Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). [GOC:ascb_2009, GOC:dph, GOC:tb]


negative regulation of sphingolipid biosynthetic process

Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). [GOC:ascb_2009, GOC:dph, GOC:tb]


Any biological process involved in the maintenance of an internal steady state of sphingolipids at the level of the cell. [GOC:ascb_2009, GOC:dph, GOC:tb]


endoplasmic reticulum membrane organisation

endoplasmic reticulum membrane organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane. [GOC:ascb_2009, GOC:dph, GOC:tb]


sphingolipid biosynthesis involved in endoplasmic reticulum membrane organisation

sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization

The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization. [GOC:ascb_2009, GOC:dph, GOC:tb]


The directed movement of substances from the Golgi to lysosomes. [GOC:ascb_2009, GOC:dph, GOC:tb]


The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae. [GOC:ascb_2009, GOC:dph, GOC:tb]


establishment of epithelial cell polarity

The specification and formation of anisotropic intracellular organization of an epithelial cell. [GOC:ascb_2009, GOC:dph, GOC:tb]


establishment of epithelial cell planar polarity

The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue. [GOC:ascb_2009, GOC:dph, GOC:tb]


The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of secretion by asymmetric Golgi ribbon formation

The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell. [GOC:ascb_2009, GOC:dph, GOC:tb]


A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division. [GOC:ascb_2009, GOC:dph, GOC:tb]


The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. [GOC:ascb_2009, GOC:dph, GOC:tb]


The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. [GOC:ascb_2009, GOC:dph, GOC:tb]


microtubule cytoskeleton organisation involved in homologous chromosome segregation

microtubule organization involved in chromosome pairing

microtubule cytoskeleton organization involved in homologous chromosome segregation

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of synaptonemal complex assembly

Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed. [GOC:ascb_2009, GOC:dph, GOC:tb]


The joining of two lipid bilayers to form a single organelle membrane. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of establishment of planar polarity

Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates. [GOC:ascb_2009, GOC:dph, GOC:tb]


microtubule cytoskeleton organisation involved in establishment of planar polarity

microtubule cytoskeleton organization involved in establishment of planar polarity

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity. [GOC:ascb_2009, GOC:dph, GOC:tb]


establishment of planar polarity involved in neural tube closure

Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of establishment of planar polarity involved in neural tube closure

Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. [GOC:ascb_2009, GOC:dph, GOC:tb]


planar cell polarity pathway involved in neural tube closure

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure. [GOC:ascb_2009, GOC:dph, GOC:tb]


positive regulation of thiamin biosynthetic process

positive regulation of thiamine biosynthetic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine. [GOC:dph, GOC:tb]


regulation of cholesterol metabolic process

Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:BHF, GOC:dph, GOC:tb]


regulation of secretion of lysosomal enzymes

Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell. [GOC:BHF, GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:dph, GOC:tb, GOC:yaf]


positive regulation of kidney development

Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:dph, GOC:tb, GOC:yaf]


negative regulation of kidney development

Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:dph, GOC:tb, GOC:yaf]


regulation of pancreatic juice secretion

Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. [GOC:dph, GOC:tb]


positive regulation of pancreatic juice secretion

Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of pancreatic juice secretion

Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. [GOC:BHF, GOC:dph, GOC:tb]


regulation of branching involved in ureteric bud morphogenesis

Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. [GOC:dph, GOC:tb, GOC:yaf]


positive regulation of branching involved in ureteric bud morphogenesis

Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. [GOC:dph, GOC:tb, GOC:yaf]


negative regulation of branching involved in ureteric bud morphogenesis

Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. [GOC:dph, GOC:tb, GOC:yaf]


Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. [GOC:dph, GOC:tb, GOC:yaf]


positive regulation of glomerulus development

Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. [GOC:dph, GOC:tb, GOC:yaf]


negative regulation of glomerulus development

Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. [GOC:dph, GOC:tb, GOC:yaf]


regulation of release of cytochrome c from mitochondria

Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. [GOC:dph, GOC:mtg_apoptosis, GOC:tb]


positive regulation of release of cytochrome c from mitochondria

Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


negative regulation of release of cytochrome c from mitochondria

Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


A process in which a protein is transported to, or maintained in, a nuclear pore. [GOC:dph, GOC:rb, GOC:tb]


positive regulation of cholesterol metabolic process

Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:dph, GOC:sl, GOC:tb]


negative regulation of cholesterol metabolic process

Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:dph, GOC:sl, GOC:tb]


regulation of triglyceride metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. [GOC:dph, GOC:sl, GOC:tb]


positive regulation of triglyceride metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. [GOC:dph, GOC:sl, GOC:tb]


negative regulation of triglyceride metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. [GOC:dph, GOC:sl, GOC:tb]


regulation of establishment of blood-brain barrier

Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. [GOC:dph, GOC:tb]


positive regulation of establishment of BBB

positive regulation of establishment of blood-brain barrier

Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of establishment of BBB

negative regulation of establishment of blood-brain barrier

Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain. [GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur. [GOC:tb]


regulation of radial pattern specification


spongiotrophoblast layer developmental growth

The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state. [GOC:dph, GOC:tb]


regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity

Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. [GOC:dph, GOC:tb]


positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity

Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. [GOC:dph, GOC:tb]


negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity

Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. [GOC:dph, GOC:tb]


positive regulation of lipid kinase activity

Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. [GOC:dph, GOC:tb]


negative regulation of lipid kinase activity

Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. [GOC:dph, GOC:tb]


chromosome localisation to nuclear envelope involved in homologous chromosome segregation

chromosome localization to nuclear envelope involved in homologous chromosome segregation

The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis. [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:19913287]


mitotic spindle-templated microtubule nucleation

The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome. [GOC:ascb_2009, GOC:dph, GOC:tb]


The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the number of microtubules in a given region of the spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of microtubule nucleation by Ran protein signal transduction

The series of molecular signals in which a Ran GTPase relays a signal resulting in the modulation of the rate, frequency or extent of microtubule nucleation. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of phytochrome signaling pathway

regulation of red or far-red light signalling pathway

regulation of red or far-red light signaling pathway

Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. [GOC:tb]


positive regulation of phytochrome signaling pathway

positive regulation of red or far-red light signalling pathway

positive regulation of red or far-red light signaling pathway

Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. [GOC:tb]


negative regulation of phytochrome signaling pathway

negative regulation of red or far-red light signalling pathway

negative regulation of red or far-red light signaling pathway

Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. [GOC:tb]


regulation of centromere complex assembly

Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


positive regulation of spindle checkpoint

Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


negative regulation of spindle checkpoint

Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of chromosome-kinetochore attachment


regulation of metaphase plate congression

Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of arachidonic acid secretion

Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue. [GOC:dph, GOC:tb]


positive regulation of arachidonic acid secretion

Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue. [GOC:BHF, GOC:dph, GOC:tb]


Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. [GOC:dph, GOC:tb]


positive regulation of histone H4 acetylation

Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. [GOC:dph, GOC:tb]


negative regulation of histone H4 acetylation

Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group. [GOC:dph, GOC:tb]


retinoic acid receptor signalling pathway involved in somitogenesis

retinoic acid receptor signaling pathway involved in somitogenesis

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


fibroblast growth factor receptor signalling pathway involved in somitogenesis

fibroblast growth factor receptor signaling pathway involved in somitogenesis

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


Wnt-activated signaling pathway involved in somitogenesis

Wnt receptor signaling pathway involved in somitogenesis

Wnt signaling pathway involved in somitogenesis

The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


axis elongation involved in somitogenesis

The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


convergent extension involved in somitogenesis

The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


cell migration involved in somitogenic axis elongation

Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of cell motility involved in somitogenic axis elongation


cell-cell adhesion involved in establishment of planar polarity

The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity. [GOC:ascb_2009, GOC:dph, GOC:tb]


protein localisation involved in establishment of planar polarity

protein localization involved in establishment of planar polarity

Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity. [GOC:ascb_2009, GOC:dph, GOC:tb]


epithelium migration involved in imaginal disc-derived wing morphogenesis

The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


convergent extension involved in imaginal disc-derived wing morphogenesis

The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


cell elongation involved in imaginal disc-derived wing morphogenesis

The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


cell proliferation involved in imaginal disc-derived wing morphogenesis

The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis

Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. [GOC:ascb_2009, GOC:dph, GOC:tb]


Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. [GOC:dph, GOC:tb]


negative regulation of mitochondrial division

negative regulation of mitochondrial fission

Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. [GOC:sl, GOC:tb]


regulation of retinal ganglion cell axon guidance

Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. [GOC:tb, GOC:yaf]


negative regulation of retinal ganglion cell axon guidance

Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. [GOC:tb, GOC:yaf]


positive regulation of inclusion body assembly

Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. [GOC:tb]


regulation of transcription-coupled nucleotide-excision repair

Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway. [GOC:tb]


positive regulation of canonical Wnt receptor signalling pathway

positive regulation of canonical Wnt-activated signaling pathway

positive regulation of Wnt receptor signaling pathway through beta-catenin

positive regulation of canonical Wnt receptor signaling pathway

positive regulation of canonical Wnt signaling pathway

Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:tb]


regulation of immune complex clearance by monocytes and macrophages

Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages. [GOC:tb]


positive regulation of immune complex clearance by monocytes and macrophages

Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages. [GOC:BHF]


regulation of mitotic cell cycle spindle assembly checkpoint

Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. [GOC:mtg_cell_cycle]


positive regulation of mitotic cell cycle spindle assembly checkpoint

Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. [GOC:mah, GOC:vw]


activation of mitotic cell cycle spindle assembly checkpoint

Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint. [GOC:mah, GOC:vw]


The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF]


regulation of fibroblast growth factor production

Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF]


positive regulation of fibroblast growth factor production

Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF]


negative regulation of fibroblast growth factor production

Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF]


Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. [GOC:BHF]


positive regulation of somatostatin secretion

Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. [GOC:BHF]


negative regulation of somatostatin secretion

Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. [GOC:BHF]


Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. [GOC:tb]


positive regulation of peptide hormone secretion

Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. [GOC:tb]


negative regulation of peptide hormone secretion

Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. [GOC:tb]


Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. [GOC:BHF]


positive regulation of calcium ion import

Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. [GOC:BHF]


negative regulation of calcium ion import

Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. [GOC:BHF]


activation of transcription involved in G2/M transition of mitotic cell cycle

activation of G2/M-specific transcription in the mitotic cell cycle

activation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle

up-regulation of transcription involved in G2/M transition of mitotic cell cycle

positive regulation of G2/M-specific transcription in the mitotic cell cycle

up-regulation of G2/M-specific transcription in the mitotic cell cycle

up-regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle

positive regulation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle

positive regulation of transcription involved in G2/M transition of mitotic cell cycle

Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle. [GOC:rn, PMID:10747051, PMID:10894548, PMID:10899128, PMID:10959837]


regulation of cellular response to growth factor stimulus

Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. [GOC:tb]


negative regulation of cellular response to growth factor stimulus

Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. [GOC:BHF]


Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. [GOC:tb]


positive regulation of osteoclast proliferation

Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. [GOC:tb]


negative regulation of osteoclast proliferation

Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. [GOC:tb]


nucleoskeleton anchoring at nuclear membrane

nuclear matrix anchoring at nuclear membrane

The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane. [GOC:tb]


regulation of transcription by nitrogen catabolites

nitrogen catabolite regulation of transcription

A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. [GOC:mah, GOC:rb, PMID:19104072]


positive regulation of transcription by nitrogen catabolites

nitrogen catabolite activation of transcription

A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. [GOC:mah, GOC:rb, PMID:19104072]


negative regulation of transcription by nitrogen catabolites

nitrogen catabolite repression of transcription

A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources. [GOC:mah, GOC:rb, PMID:19104072]


regulation of mitochondrial DNA replication

Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. [GOC:tb]


positive regulation of mitochondrial DNA replication

Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. [GOC:tb]


negative regulation of mitochondrial DNA replication

Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion. [GOC:tb]


Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. [GOC:tb]


positive regulation of neural crest formation

Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. [GOC:tb]


negative regulation of neural crest formation

Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. [GOC:tb]


Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. [GOC:BHF]


regulation of transcription involved in G2/M transition of mitotic cell cycle

Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle. [GOC:mtg_cell_cycle]


conversion of mitochondrial met-tRNAf to fmet-tRNA


mitochondrial N-terminal peptidyl-methionine N-formylation


fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity


water transmembrane transporter activity

Enables the transfer of water (H2O) from one side of a membrane to the other. [GOC:ai]


Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. [GOC:bf, GOC:jl]


major (U2-type) spliceosomal complex location

Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends. [GOC:krc, GOC:mah, PMID:11343900]


minor (U12-type) spliceosomal complex location

Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site. [GOC:krc, GOC:mah, PMID:11574683, PMID:11971955]


Sec61 translocon complex location
Sec61p-Sbh1p-Sss1p complex
Sec61p-Sbh1p-Sss1p complex location

A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events. [GOC:mah, PMID:18166647, PMID:32820719, PMID:33960686]


regulation of gene expression by genetic imprinting

regulation of gene expression by DNA imprinting

regulation of gene expression by genomic imprinting

An epigenetic mechanism of regulation of gene expression in which epigenetic modifications (imprints) are established during gametogenesis. For a given gene to show parentally biased expression, the imprint are established exclusively in one of the two parental genomes, thus generating an asymmetry between the maternal and paternal alleles. [PMID:11498578, PMID:31896690, PMID:7502071]


heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell. [ISBN:0198506732]


The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups. [PMID:15057936]


Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern. [GOC:bf, ISBN:0879694238, PMID:9550716]


Assembly of the intercellular bridges that connect the germ-line cells of a female cyst. [ISBN:0879694238]


zygotic specification of dorsal/ventral axis

The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote. [GOC:bf]


The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo. [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


anterior compartment pattern specification


tracheal placode cell fate determination


mammalian spliceosomal complex E location

mammalian spliceosomal E complex location


bud site selection/establishment of cell polarity


structural constituent of larval cuticle


dorsal/ventral axis determination, follicular epithelium


G-protein coupled amine receptor activity

amine receptor activity, G-protein coupled

G protein-coupled amine receptor activity

Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. [GOC:bf, GOC:dph]


female germline ring canal formation, actin assembly

Recruitment and organization of actin filaments in female germline ring canals. [ISBN:0879694238]


nurse cell ring canal formation, actin assembly


ovarian ring canal formation, actin assembly


female germline ring canal stabilization

Maintenance of the structural integrity of the ring canals connecting the female germline cyst. [GOC:curators]


The pathways that regulate the duration of the adult phase of the life-cycle of an animal. [PMID:25561524, PMID:273723695, PMID:3424805]


adult cuticle formation
adult cuticle biosynthetic process
adult cuticle synthesis


anterior/posterior axis specification, embryo

The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote. [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


OBSOLETE. An activity involved in the removal of an intron from a pre-mRNA. [GOC:jl]


The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome. [GOC:krc, GOC:mah, ISBN:0879695897]


karyogamy involved in conjugation without cellular fusion

karyogamy involved in conjugation with mutual genetic exchange

During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena. [GOC:mah, GOC:pg]


nuclear migration involved in conjugation without cellular fusion

nuclear migration involved in conjugation with mutual genetic exchange

The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion. [GOC:clt, GOC:mah]


pheromone-dependent signal transduction involved in conjugation with cellular fusion

A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae. [GOC:clt]


cell morphogenesis involved in conjugation with cellular fusion

The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion. [GOC:clt]


response to pheromone triggering conjugation without cellular fusion

response to pheromone regulating conjugation with mutual genetic exchange

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion. [GOC:clt]


agglutination involved in conjugation without cellular fusion

agglutination involved in conjugation with mutual genetic exchange

The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism. [GOC:elh]


The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created. [GOC:go_curators]


NAD(P)H dehydrogenase complex (plastoquinone) assembly


chlorophyll catabolite transmembrane transporter activity

Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other. [PMID:9681016]


regulation of budding cell apical bud growth

Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding. [GOC:dph, GOC:jp, GOC:tb, PMID:17417630]


macrophage derived foam cell differentiation

The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:dph, GOC:tb]


regulation of macrophage derived foam cell differentiation

Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:BHF, GOC:dph, GOC:tb]


positive regulation of macrophage derived foam cell differentiation

Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:dph, GOC:tb]


negative regulation of macrophage derived foam cell differentiation

Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:BHF, GOC:dph, GOC:tb]


Catalysis of the reaction: coenzyme A or its derivatives + H2O = 3',5'-ADP + 4'-phosphopantetheine. [GOC:tb, PMID:10922370, PMID:16185196]


regulation of meiotic joint molecule formation

Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. [GOC:dph, GOC:tb]


negative regulation of meiotic joint molecule formation

Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. [GOC:dph, GOC:tb]


negative regulation of cell cycle process

Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [GOC:dph, GOC:tb]


negative regulation of intestinal phytosterol absorption

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of endopeptidase activity

Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. [GOC:dph, GOC:tb]


negative regulation of endopeptidase activity

Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins. [GOC:dph, GOC:tb]


positive regulation of peptidase activity

Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. [GOC:dph, GOC:tb]


negative regulation of calcidiol 1-monooxygenase activity

Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of vitamin D biosynthetic process

Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). [GOC:BHF, GOC:dph, GOC:tb]


Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell. [GOC:dph, GOC:tb]


Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell. [GOC:dph, GOC:tb]


regulation of glucan biosynthetic process

Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. [GOC:dph, GOC:tb]


regulation of chromatin silencing by small RNA


regulation of mitotic sister chromatid separation

Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. [GOC:dph, GOC:tb]


Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


regulation of polyamine biosynthetic process

Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. [GOC:dph, GOC:tb]


Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. [GOC:dph, GOC:tb]


regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion

Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. [GOC:dph, GOC:tb]


A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. [GOC:cjm, ISBN:0815316194]


positive regulation of G2/M transition of mitotic cell cycle

Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. [GOC:dph, GOC:mtg_cell_cycle, GOC:tb]


negative regulation of G2/M transition of mitotic cell cycle

Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle. [GOC:mtg_cell_cycle]


positive regulation of division septum formation involved in cell cycle cytokinesis

upregulation of mitotic division septum assembly

positive regulation of division septum assembly

Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. [GOC:mtg_cell_cycle, PMID:19959363, PMID:21246752, PMID:22786806]


negative regulation of division septum formation

negative regulation of division septum assembly

Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. [GOC:mtg_cell_cycle, PMID:19959363, PMID:21246752, PMID:22786806]


regulation of neurite formation
regulation of neurite biosynthesis
regulation of neurite growth
regulation of neurite development

regulation of neuron projection development

Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). [GOC:dph, GOC:tb]


positive regulation of neurite formation

positive regulation of neurite biosynthesis

positive regulation of neurite development

positive regulation of neuron projection development

Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). [GOC:dph, GOC:tb]


negative regulation of neurite formation

negative regulation of neurite biosynthesis

negative regulation of neurite development

negative regulation of neuron projection development

Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). [GOC:dph, GOC:tb]


regulation of vitamin D 24-hydroxylase activity

Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of vitamin D 24-hydroxylase activity

Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D. [GOC:BHF, GOC:dph, GOC:tb]


regulation of cell wall macromolecule metabolic process

Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. [GOC:dph, GOC:tb]


regulation of high-density lipoprotein particle clearance

Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of high-density lipoprotein particle clearance

Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


regulation of lipoprotein particle clearance

Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of lipoprotein particle clearance

Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


positive regulation of lipoprotein particle clearance

Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of high-density lipoprotein particle clearance

Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


regulation of low-density lipoprotein particle clearance

Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of low-density lipoprotein particle clearance

Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


regulation of SMAD protein complex assembly

Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. [GOC:BHF, GOC:dph, GOC:tb]


negative regulation of SMAD protein complex assembly

Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins. [GOC:BHF, GOC:dph, GOC:tb]


The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein. [GOC:BHF, GOC:dph, GOC:tb]


The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down. [GOC:BHF, GOC:dph, GOC:tb]


response to auditory stimulus
response to sound stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus. [GOC:BHF, GOC:dph, GOC:sl, GOC:tb]


Binding to an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. [GOC:BHF, GOC:dph, GOC:tb]


regulation of translational initiation by eIF2 alpha phosphorylation in response to stress

Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha. [GOC:BHF, GOC:dph, GOC:hjd, GOC:tb]


regulation of eIF2 alpha phosphorylation by heme

Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels. [GOC:BHF, GOC:dph, GOC:tb]


replication fork arrest at mating type locus

A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus. [GOC:dph, GOC:tb]


establishment of endothelial blood/brain barrier

establishment of endothelial blood-brain barrier

Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier. [GOC:aruk, GOC:dgh, GOC:dph, GOC:sart, PMID:20080302, PMID:30280653]


The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. [CL:0000737, GOC:dph, GOC:mtg_muscle]


cardiac muscle hypertrophy in response to stress

The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_muscle]


haem lyase disulphide oxidoreductase activity

heme lyase disulfide oxidoreductase activity


secondary active cyanate transmembrane transporter activity

Enables the transfer of cyanate from one side of a membrane to the other. [TC:2.A.1.17.1]


protein secretion by the general secretory pathway

protein secretion by the general secretion pathway


regulation of striated muscle tissue development

Any process that modulates the frequency, rate or extent of striated muscle development. [GOC:go_curators]


cyclin-dependent protein kinase 5 holoenzyme complex location


negative regulation of RNA polymerase II transcriptional preinitiation complex assembly

downregulation of RNA polymerase II transcriptional preinitiation complex assembly

inhibition of RNA polymerase II transcriptional preinitiation complex assembly

down-regulation of RNA polymerase II transcriptional preinitiation complex assembly

negative regulation of RNA polymerase II transcriptional pre-initiation complex assembly

negative regulation of RNA polymerase II transcriptional preinitiation complex formation

negative regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis

down regulation of RNA polymerase II transcriptional preinitiation complex assembly

negative regulation of RNA polymerase II transcription preinitiation complex assembly

Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly. [GOC:go_curators]


The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid. [GOC:jsg, ISBN:0198506732]


coenzyme F420-independent methylene-H4MPT dehydrogenase activity

coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity

Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin. [UM-BBD_reactionID:r0353]


Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O. [MetaCyc:R461-RXN, UM-BBD_reactionID:r0127]


Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde. [UM-BBD_reactionID:r0484]


fruiting body formation involved in asexual reproduction


fruiting body formation involved in sexual reproduction


cytokinesis, actomyosin contractile ring assembly

cytokinesis, actomyosin contractile ring formation

The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis. [GOC:clt, GOC:dph, GOC:tb]


An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed. [GOC:krc]


tRNA exon ligation utilizing ATP as source of linkage phosphate

A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species. [GOC:krc, PMID:17786051]