Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline. [EC:2.1.1.116]


Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.83, RHEA:21832]


Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.97, RHEA:17833]


Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine. [EC:2.1.1.82, RHEA:16181]


Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin. [EC:2.1.1.69]


Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.108, RHEA:15201]


Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline. [EC:2.1.1.121]


Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin. [EC:2.1.1.70]


Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.88, RHEA:16593]


Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine. [EC:2.1.1.49]


anthranilic acid N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.111, RHEA:12180]


Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone. [EC:2.1.1.75]


Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate. [EC:2.1.1.137]


Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+). [EC:2.1.1.22, RHEA:14205]


Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole. [EC:2.1.1.136]


Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine. [EC:2.1.1.118, RHEA:15373]


Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.142, RHEA:13137]


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin. [EC:2.1.1.102, RHEA:17573]


Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine. [EC:2.1.1.44]


Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate. [EC:2.1.1.112]


Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+). [EC:2.1.1.2, RHEA:10656]


indolepyruvic acid methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate. [EC:2.1.1.47]


inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.40, RHEA:17565]


myo-inositol 1-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.39, RHEA:18877]


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.129, RHEA:23248]


Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.26, RHEA:14313]


Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.91, RHEA:10996]


Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone. [EC:2.1.1.46]


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin. [EC:2.1.1.78, RHEA:24096]


S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase activity

methyl jasmonate methylesterase activity

Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonate = S-adenosyl-L-homocysteine + a methyljasmonate. [RHEA:13349]


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.65, RHEA:18521]


S-adenosyl-L-methionine:loganic acid methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin. [EC:2.1.1.50]


o-dihydric phenol meta-O-methyltransferase activity

o-dihydric phenol methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.42, RHEA:14589]


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin. [EC:2.1.1.101, RHEA:17269]


S-adenosyl methionine:methionine methyl transferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine. [EC:2.1.1.12]


Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate. [EC:2.1.1.138]


Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.84, RHEA:18717]


Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.105, RHEA:17405]


Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin. [EC:2.1.1.38]


Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+). [EC:2.1.1.25, RHEA:14809]


Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units. [EC:2.1.1.18]


Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H(+) + precorrin-3A. [EC:2.1.1.130, RHEA:16841]


Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4. [EC:2.1.1.131]


Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.53, RHEA:15037]


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine. [EC:2.1.1.87, RHEA:16893]


Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone. [EC:2.1.1.76]


Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine. [EC:2.1.1.89, RHEA:22536]


Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine. [EC:2.1.1.144, RHEA:14969]


Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+). [EC:2.1.1.106, RHEA:17321]


DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid)

Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+). [EC:2.1.1.27, RHEA:14865]


S-adenosyl-L-methionine:cytochrome c-methionine S-methyltransferase activity

[cytochrome c]-methionine S-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine. [EC:2.1.1.123]


S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity

ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity

ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity

S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity

[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine. [EC:2.1.1.127]


Catalysis of the reaction: L-homocysteine + betaine = N,N-dimethylglycine + L-methionine. [EC:2.1.1.5, RHEA:22336]


Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H(+). [EC:2.1.1.3, RHEA:22788]


ATP nucleotide 3'-pyrophosphokinase activity

Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate. [EC:2.7.6.4, MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN]


CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity

Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate. [EC:2.7.7.60, RHEA:13429]


Catalysis of the reaction: 5'-adenylyl sulfate + NH(4)(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate. [EC:2.7.7.51, RHEA:19197]


adenosine diphosphate glucose:orthophosphate adenylyltransferase activity

adenosine diphosphosugar phosphorylase activity

Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose. [EC:2.7.7.36, MetaCyc:2.7.7.36-RXN]


nucleoside diphosphosugar phosphorylase activity

glucose 1-phosphate inosityltransferase activity

sugar phosphate nucleotidyltransferase activity

nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase activity

Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose. [EC:2.7.7.37, MetaCyc:2.7.7.37-RXN]


anthranilic acid adenylyltransferase activity

Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H(+). [PMID:2995633, RHEA:35091]


cytidine diphosphoribitol pyrophosphorylase activity

cytidine diphosphate ribitol pyrophosphorylase activity

ribitol 5-phosphate cytidylyltransferase activity

Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate. [EC:2.7.7.40, RHEA:12456]


guanosine diphosphate L-fucose pyrophosphorylase activity

Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP = diphosphate + GDP-L-fucose. [EC:2.7.7.30, RHEA:13549]


dTDP galactose pyrophosphorylase activity

thymidine triphosphate:alpha-D-galactose 1-phosphate thymidylyltransferase activity

thymidine diphosphogalactose pyrophosphorylase activity

galactose 1-phosphate thymidylyl transferase activity

Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose. [EC:2.7.7.32, RHEA:17165]


cytidine diphosphate-D-glucose pyrophosphorylase activity

cytidine diphosphoglucose pyrophosphorylase activity

cytidine diphosphate glucose pyrophosphorylase activity

Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate. [EC:2.7.7.33, RHEA:18213]


guanosine diphosphoglucose pyrophosphorylase activity

Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose. [EC:2.7.7.34, RHEA:10708]


UDP-glucuronic acid pyrophosphorylase activity

UDP-D-glucuronic acid pyrophosphorylase activity

uridine diphosphoglucuronic pyrophosphorylase activity

Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate. [EC:2.7.7.44, RHEA:16325]


cytidine diphosphoglycerol pyrophosphorylase activity

CTP:glycerol 3-phosphate cytidylyltransferase activity

cytidine diphosphate glycerol pyrophosphorylase activity

Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate. [EC:2.7.7.39, RHEA:13361]


Catalysis of the reaction: 2 GTP = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H(+). [EC:2.7.7.45, RHEA:18153]


monomethylethanolamine phosphate cytidylyltransferase activity

Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate. [EC:2.7.7.57, RHEA:10576]


hexose 1-phosphate guanylyltransferase activity

nucleoside diphosphohexose pyrophosphorylase activity

hexose 1-phosphate nucleotidyltransferase activity

Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate. [EC:2.7.7.28, MetaCyc:2.7.7.28-RXN]


Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+). [EC:2.7.7.54, RHEA:17189]


adenosine diphosphoribose phosphorylase activity

Catalysis of the reaction: D-ribose 5-phosphate + ADP + H(+) = ADP-ribose + phosphate. [EC:2.7.7.35, RHEA:14529]


Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1). [EC:2.7.7.52, MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN]


uridine diphosphoxylose pyrophosphorylase activity

xylose 1-phosphate uridylyltransferase activity

Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate. [EC:2.7.7.11, MetaCyc:2.7.7.11-RXN]


ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase activity

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity

Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+). [EC:2.7.1.148, RHEA:18437]


Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate. [EC:2.7.1.92, MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN]


hexose phosphate:hexose phosphotransferase activity

Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid. [EC:2.7.1.61, MetaCyc:2.7.1.61-RXN]


Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate. [EC:2.7.1.94, MetaCyc:ACYLGLYCEROL-KINASE-RXN]


adenosine diphosphate-thymidine phosphotransferase activity

Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate. [EC:2.7.1.118, MetaCyc:ADP--THYMIDINE-KINASE-RXN]


Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H(+). [EC:2.7.1.93, RHEA:16937]


Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H(+). [EC:2.7.1.84, RHEA:23088]


adenylic acid:deoxythymidine 5'-phosphotransferase activity

Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate. [EC:2.7.1.114, MetaCyc:AMP--THYMIDINE-KINASE-RXN]


beta-adrenergic-receptor kinase (phosphorylating) activity

beta-adrenergic receptor-specific kinase activity

beta-adrenergic receptor kinase activity

Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor. [EC:2.7.11.15, MetaCyc:BETA-ADRENERGIC-RECEPTOR-KINASE-RXN]


Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose. [EC:2.7.1.85, MetaCyc:BETA-GLUCOSIDE-KINASE-RXN]


Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP. [EC:2.7.1.54, RHEA:24588]


Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H(+). [EC:2.7.1.13, RHEA:10788]


dephospho-reductase kinase kinase activity

ATP:dephospho-{hydroxymethylglutaryl-CoA reductase (NADPH)kinase} phosphotransferase activity

dephospho-[reductase kinase] kinase activity

hydroxymethylglutaryl coenzyme A reductase kinase kinase activity

hydroxymethylglutaryl coenzyme A reductase kinase kinase (phosphorylating) activity

Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase]. [EC:2.7.11.3, MetaCyc:DEPHOSPHO-REDUCTASE-KINASE-KINASE-RXN]

AMP-activated protein kinase kinase activity


dihydrostreptomycin 6-phosphate kinase (phosphorylating)

Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H(+). [EC:2.7.1.88, RHEA:16281]


inorganic pyrophosphate-dependent phosphofructokinase activity

pyrophosphate--fructose 6-phosphate 1-phosphotransferase activity

pyrophosphate-fructose 6-phosphate phosphotransferase activity

Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate. [EC:2.7.1.90, MetaCyc:2.7.1.90-RXN]


Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H(+) + phosphate. [EC:2.7.1.79, RHEA:13689]


Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein. [EC:2.7.99.1, MetaCyc:2.7.99.1-RXN]


Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H(+) + phosphate. [EC:2.7.1.80, RHEA:23764]


Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H(+). [EC:2.7.1.27, RHEA:20708]


Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+). [EC:2.7.1.52, RHEA:13241]


galacturonokinase (phosphorylating) D-galacturonic acid kinase activity

Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H(+). [EC:2.7.1.44, RHEA:12965]


Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate. [EC:2.7.1.8, MetaCyc:GLUCOSAMINE-KINASE-RXN]


glucose 1,6-diphosphate synthase activity

Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H(+). [EC:2.7.1.106, RHEA:16769]


glucose 1-phosphate transphosphorylase activity

Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate. [EC:2.7.1.41, MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN]


Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H(+). [EC:2.7.1.43, RHEA:17005]


Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol. [EC:2.7.1.142, RHEA:21288]


hamamelosekinase (ATP: hamamelose 2'-phosphotransferase)

Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H(+). [EC:2.7.1.102, RHEA:22796]


guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase activity

Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H(+). [EC:2.7.1.81, RHEA:19049]


inositol polyphosphate multikinase activity

Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H(+). [MetaCyc:2.7.1.151-RXN]


inositol tetrakisphosphate 1-kinase activity

inositol 3,4,5,6-tetrakisphosphate 1-kinase activity

Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. [EC:2.7.1.134, MetaCyc:2.7.1.134-RXN]


inositol tetrakisphosphate 5-kinase activity

inositol 1,3,4,6-tetrakisphosphate 5-kinase activity

Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP. [EC:2.7.1.140, MetaCyc:2.7.1.140-RXN]


Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2'-O-phosphate. [EC:2.7.1.136, RHEA:18333]


nonspecific nucleoside phosphotransferase activity

Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate. [EC:2.7.1.77, MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN]


Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate. [EC:2.7.1.34, MetaCyc:PANTETHEINE-KINASE-RXN]


Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate. [EC:2.7.1.121, RHEA:18381]


Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+). [EC:2.7.1.10, RHEA:13377]


Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3. [EC:2.7.1.62, MetaCyc:2.7.1.62-RXN]


Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+). [EC:2.7.1.18, RHEA:21216]


Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate. [EC:2.7.1.63, MetaCyc:2.7.1.63-RXN]


Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5'-phosphate. [EC:2.7.1.83, RHEA:22448]


rhodopsin kinase (phosphorylating) activity

Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin. [EC:2.7.11.14, MetaCyc:RHODOPSIN-KINASE-RXN]


Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN. [EC:2.7.1.42, RHEA:20409]


Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide. [EC:2.7.1.22, PMID:17914902, RHEA:14017]


Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+). [EC:2.7.1.65, RHEA:18605]


Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate. [EC:2.7.1.14, RHEA:23844]


Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3''-phosphate. [EC:2.7.1.87, RHEA:18377]


tagatose 6-phosphate kinase (phosphorylating)

Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+). [EC:2.7.1.101, RHEA:15513]


[Tau protein] kinase activity
glycogen synthase kinase-3beta activity
tau kinase activity
GSK
STK31
tau-protein kinase activity
TPK I
TTK
protein tau kinase activity
TPK
tau protein kinase activity

Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein. [EC:2.7.11.26, MetaCyc:TAU-PROTEIN-KINASE-RXN]


Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+). [EC:2.7.1.28, RHEA:13941]


tropomyosin kinase (phosphorylating) activity

Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin. [EC:2.7.11.28, MetaCyc:TROPOMYOSIN-KINASE-RXN]


Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin. [EC:2.7.1.103, MetaCyc:VIOMYCIN-KINASE-RXN]


Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate. [EC:2.7.1.122, RHEA:20209]


ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity

branched-chain 2-oxo acid dehydrogenase kinase activity

branched-chain keto acid dehydrogenase kinase activity

[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity

branched-chain alpha-ketoacid dehydrogenase kinase activity

3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity

branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity

Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate. [EC:2.7.11.4]

[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity


ATP:acetyl-CoA carboxylase phosphotransferase activity

acetyl coenzyme A carboxylase kinase (phosphorylating) activity

acetyl-CoA carboxylase kinase (AMP-activated) activity

[acetyl-CoA carboxylase] kinase activity

acetyl-CoA carboxylase kinase (cAMP-independent) activity

acetyl-coenzyme A carboxylase kinase activity

Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate. [EC:2.7.11.27, MetaCyc:[ACETYL-COA-CARBOXYLASE]-KINASE-RXN]


ATP:hydroxymethylglutaryl-CoA reductase (NADPH) phosphotransferase activity

hydroxymethylglutaryl coenzyme A reductase kinase activity

[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity

beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activity

3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity

hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity

hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity

hydroxymethylglutaryl-CoA reductase kinase activity

3-hydroxy-3-methylglutaryl-CoA reductase kinase activity

Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP. [EC:2.7.11.31, MetaCyc:2.7.1.109-RXN]

hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activity


pheochromocytoma tyrosine hydroxylase-associated kinase activity

[tyrosine 3-monooxygenase] kinase activity

tyrosine 3-monooxygenase kinase activity

Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase]. [EC:2.7.11.6, MetaCyc:TYROSINE-3-MONOOXYGENASE-KINASE-RXN]

tyrosine 3-monooxygenase kinase (phosphorylating) activity


Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate. [EC:2.7.2.12, RHEA:24276]


branched-chain fatty acid kinase activity


Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H(+). [EC:2.7.2.7, RHEA:13585]


Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H(+). [EC:2.7.2.6, RHEA:16009]


Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+). [EC:2.7.2.10, RHEA:23332]


1-alkenyl-2-acylglycerol choline phosphotransferase activity

Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP. [EC:2.7.8.22, MetaCyc:2.7.8.22-RXN]


teichoic acid glycerol transferase activity

poly(glycerol phosphate) polymerase activity

cytidine diphosphoglycerol glycerophosphotransferase activity

Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP. [EC:2.7.8.12, MetaCyc:2.7.8.12-RXN]


polyribitol phosphate polymerase activity

CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase activity

poly(ribitol phosphate) synthetase activity

polyribitol phosphate synthetase activity

Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP. [EC:2.7.8.14, MetaCyc:2.7.8.14-RXN]


Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin. [EC:2.7.8.3, RHEA:16273]


Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another. [EC:2.7.8.21]


Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+). [EC:2.7.8.24, RHEA:14597]


GDP-mannose:phosphomannan mannose phosphotransferase activity

Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP. [EC:2.7.8.9, MetaCyc:2.7.8.9-RXN]


serine ethanolamine phosphate synthetase activity

CDP-ethanolamine:L-serine ethanolamine phosphotransferase activity

serine ethanolamine phosphodiester synthase activity

Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H(+). [EC:2.7.8.4, RHEA:22656]


sphingosine choline phosphotransferase activity

cytidine diphosphocholine-sphingosine cholinephosphotransferase activity

Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine. [EC:2.7.8.10, RHEA:21224]


ATP:dephospho-CoA 5-triphosphoribosyl transferase activity

Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine. [EC:2.4.2.52]


UDPgalactose-UDP-N-acetylglucosamine galactose phosphotransferase activity

UDPgalactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity

uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase activity

UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity

UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity

Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H(+) + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP. [EC:2.7.8.18, RHEA:22440]


uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase activity

UDPglucose-glycoprotein glucose phosphotransferase activity

UDP-glucose-glycoprotein glucose phosphotransferase activity

Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP. [EC:2.7.8.19, MetaCyc:2.7.8.19-RXN]


UDP-galactose:undecaprenyl-phosphate galactose phosphotransferase activity

undecaprenyl phosphate galactosyl-1-phosphate transferase activity

poly(isoprenol)-phosphate galactose phosphotransferase activity

Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP. [EC:2.7.8.6, RHEA:11652]


Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H(+). [EC:2.7.3.10, RHEA:15953]


phosphoramidate-adenosine diphosphate phosphotransferase activity

Catalysis of the reaction: ATP + NH(4)(+) = ADP + 3 H(+) + phosphoramidate. [EC:2.7.3.8, RHEA:11024]


Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H(+) + phosphoguanidinoacetate. [EC:2.7.3.1, RHEA:14145]


Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H(+). [EC:2.7.3.6, RHEA:24008]


Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine. [EC:2.7.3.5, MetaCyc:LOMBRICINE-KINASE-RXN]


Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+). [EC:2.7.3.7, RHEA:17553]


enzyme I of the phosphotransferase system

phosphoenolpyruvate sugar phosphotransferase enzyme I activity

Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine. [EC:2.7.3.9]

phosphopyruvate--protein factor phosphotransferase activity


Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+). [EC:2.7.3.4, RHEA:22516]


ATP:alpha-glucan, water phosphotransferase activity

Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate. [EC:2.7.9.4, MetaCyc:2.7.9.4-RXN]


Catalysis of the reaction: ATP + dAMP = ADP + dADP. [EC:2.7.4.11, MetaCyc:DEOXYADENYLATE-KINASE-RXN]


deoxynucleoside monophosphate kinase activity

Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate. [EC:2.7.4.13, MetaCyc:DEOXYNUCLEOSIDE-PHOSPHATE-KINASE-RXN]


Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate. [EC:2.7.4.17, MetaCyc:2.7.4.17-RXN]


Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H(+). [EC:2.7.4.19, RHEA:11396]


Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate. [EC:2.7.4.20, MetaCyc:2.7.4.20-RXN]


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP. [RHEA:21544]


Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown. [GOC:elh, GOC:vw, PMID:16429326]

inositol hexakisphosphate kinase activity


nucleoside monophosphate kinase activity

Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate. [GOC:ai, ISBN:0198506732]


T2-induced deoxynucleotide kinase activity

Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP. [EC:2.7.4.12, MetaCyc:T2-INDUCED-DEOXYNUCLEOTIDE-KINASE-RXN]


3-oxoadipate succinyl-CoA transferase activity

3-oxoadipate coenzyme A-transferase activity

Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA. [EC:2.8.3.6, MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN]


5-hydroxyvalerate coenzyme A transferase activity

Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate. [EC:2.8.3.14, RHEA:23496]


butyryl coenzyme A-acetoacetate coenzyme A-transferase activity

Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate. [EC:2.8.3.9, RHEA:12961]


Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA. [EC:2.8.3.11, MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN]


malonate coenzyme A-transferase activity

Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA. [EC:2.8.3.3, RHEA:18817]


Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate. [EC:2.8.3.2, RHEA:23588]


citramalate coenzyme A-transferase activity

succinyl coenzyme A-citramalyl coenzyme A transferase activity

Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate. [PMID:16547052, RHEA:38287]


hydroxymethylglutarate coenzyme A-transferase activity

dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase activity

Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate. [EC:2.8.3.13, MetaCyc:2.8.3.13-RXN]


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate. [EC:2.8.2.3, MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN]


Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate. [EC:2.8.2.22, MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN]


bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate. [EC:2.8.2.14, MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN]


Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H(+). [EC:2.8.2.6, RHEA:21984]


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate. [EC:2.8.2.5, MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN]


Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H(+). [EC:2.8.2.18, RHEA:11884]


Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H(+). [EC:2.8.2.24, RHEA:20281]


Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc. [GOC:ai, PMID:11323440, PMID:11356829]


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate. [EC:2.8.2.11, PMID:10727929, RHEA:20613]


N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity

Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate. [EC:2.8.2.33]


3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate. [EC:2.8.2.13, MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN]


PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase activity

Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate. [EC:2.8.2.28, MetaCyc:2.8.2.28-RXN]


PAPS:flavonol 3-sulfate 3'-sulfotransferase activity

Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,3'-disulfate. [EC:2.8.2.26, RHEA:22504]


PAPS:flavonol 3-sulfate 4'-sulfotransferase activity

Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,4'-disulfate. [EC:2.8.2.27, RHEA:17205]


3'-phosphoadenylyl-sulfate:Renilla luciferin sulfotransferase activity

luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase)

Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H(+) + luciferyl sulfate. [EC:2.8.2.10, RHEA:20481]


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate. [EC:2.8.2.15, MetaCyc:STEROID-SULFOTRANSFERASE-RXN]


Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate. [EC:2.8.2.19, MetaCyc:2.8.2.19-RXN]


uridine diphosphoacetylgalactosamine 4-sulfate sulfotransferase activity

uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase activity

Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H(+) + UDP-N-acetyl-D-galactosamine 4,6-disulfate. [EC:2.8.2.7, RHEA:14337]


Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite. [EC:2.8.1.5, MetaCyc:2.8.1.5-RXN]


glutathione-dependent thiosulfate reductase activity

Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide. [EC:2.8.1.3, MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN]


transferase activity, transferring alkylthio groups

Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor). [GOC:ai]


Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB. [EC:2.8.4.1, RHEA:12532]


L-ornithine carboxy-lyase activator activity


ribulose-1,5-bisphosphate carboxylase/oxygenase activase activity

ribulose-bisphosphate carboxylase activase activity

Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate. [PMID:10430961, PMID:10965036, PMID:2404515]

ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity


Binds to and stops, prevents or reduces the activity of pectinesterase. [GOC:ai, PMID:10880981]


Binds to and modulates the activity of a GTPase. [GOC:mah]


histone acetyltransferase regulator activity

Binds to and modulates the activity of histone acetyltransferase. [GOC:bf]


Binds to and modulates the activity of histone deacetylase. [GOC:bf]


phosphoinositide 3-kinase regulator activity

phosphatidylinositol 3-kinase regulator activity

Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates. [GOC:bf, PMID:9255069]


1-phosphatidylinositol 3-kinase regulator activity

Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity. [GOC:ai]


methionine adenosyltransferase regulator activity

Binds to and modulates the activity of methionine adenosyltransferase. [GOC:jid, PMID:10644686]


ornithine decarboxylase regulator activity

Binds to and modulates the activity of the enzyme ornithine decarboxylase. [GOC:jl]


1-phosphatidylinositol-4-phosphate kinase, class IA

OBSOLETE. A class I PI3K activated by tyrosine phosphorylation events. [PMID:11050418]


1-phosphatidylinositol-4-phosphate kinase, class IB

OBSOLETE. A class I PI3K activated via heterotrimeric G-proteins. [PMID:11050418]


OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide. [GOC:curators]


OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O. [EC:1.9.3.1]


adhesive extracellular matrix constituent

OBSOLETE. A constituent of the extracellular matrix that facilitates attachment of cells to the matrix. [GOC:mah, ISBN:0815316194]


OBSOLETE. (Was not defined before being made obsolete). [GOC:ai]


OBSOLETE. (Was not defined before being made obsolete). [GOC:krc]


OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity. [EC:5.2.1.8, ISBN:0198506732]


OBSOLETE. A hemeprotein whose characteristic mode of action involves transfer of reducing equivalents associated with a reversible change in oxidation state of the prosthetic group. This redox change involves a single electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom. [PMID:1655423]


OBSOLETE. Diheme cytochrome b; cytochrome b has the hemes b(562) and b(566) and is a component of the mitochondrial respiratory chain complex III. Cytochrome b6 is a component of bc complex acting between photosystems II and I of photosynthesis. [ISBN:0198547684]


OBSOLETE. A cytochrome c that is an integral component of the mitochondrial respiratory complex III. Functions as an electron donor to cytochrome c. [PMID:1655423]


OBSOLETE. (Was not defined before being made obsolete). [GOC:elh]


OBSOLETE. (Was not defined before being made obsolete). [GOC:jl]


OBSOLETE. (Was not defined before being made obsolete). [GOC:mah]


OBSOLETE. Large glycoprotein that is a calcium binding component of connective tissue microfibrils containing 34 six-cysteine (EGF-like) repeats and five eight-cysteine (TGFbeta-1 binding protein-like) repeats. Defects associated with Marfan syndrome. [ISBN:0198506732]


heterotrimeric G-protein GTPase, alpha-subunit

OBSOLETE. Subunit of a heterotrimeric G-protein GTPase that contains the guanine nucleotide binding site and possesses GTPase activity. [GOC:mah, ISBN:0198547684]


heterotrimeric G-protein GTPase, beta-subunit

OBSOLETE. Subunit of a heterotrimeric G-protein GTPase; associates tightly with the gamma subunit. [GOC:mah, ISBN:0198547684]


heterotrimeric G-protein GTPase, gamma-subunit

OBSOLETE. Smallest subunit of a heterotrimeric G-protein GTPase; associates tightly with the beta subunit. [GOC:mah, ISBN:0198547684]


OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin. [ISBN:0198506732]


OBSOLETE. (Was not defined before being made obsolete). [GOC:go_curators]


Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule. [GOC:dos]


OBSOLETE. A class of ligands for neurexins. [GOC:ai]


para-aminobenzoic acid synthase activity


OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin. [ISBN:0198506732]


OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell. [GOC:jid]


OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. [GOC:jid]


RNA-directed DNA polymerase, group II intron encoded

OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo. [EC:2.7.7.49]


RNA-directed DNA polymerase, transposon encoded


OBSOLETE. A class of cell adhesion molecules that bind to carbohydrate via a lectin-like domain; integral membrane glycoproteins. [ISBN:0124325653]


OBSOLETE. Interacting selectively with the cap structure at the 5' end of a small nuclear RNA molecule. [GOC:mah]


OBSOLETE. (Was not defined before being made obsolete). [GOC:ai]


OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity. [EC:3.4.16.5]


A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. [GOC:ai, GOC:mah, ISBN:08789310662000]


advanced glycation end-product receptor activity

Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins). [GOC:signaling, PMID:12453678, PMID:12707408, PMID:7592757, PMID:9224812, Wikipedia:RAGE_(receptor)]


PGJ receptor activity
PGJ(2) receptor activity

Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity. [PMID:12878180]


extracellular matrix structural constituent

The action of a molecule that contributes to the structural integrity of the extracellular matrix. [GOC:mah]


extracellular matrix constituent conferring elasticity

A component of the extracellular matrix that enables the matrix to recoil after transient stretching. [GOC:mah, ISBN:0815316194]


extracellular matrix structural constituent conferring compression resistance

A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan. [GOC:mah, ISBN:0815316194]


extracellular matrix structural constituent conferring tensile strength

A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress. [GOC:mah, ISBN:0815316194]


amide transmembrane transporter activity

Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other. [GOC:jl, ISBN:0198506732]


L-tryptophan transmembrane transporter activity

Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]


L-tyrosine transmembrane transporter activity

Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]


L-glutamine transmembrane transporter activity

Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]


L-lysine transmembrane transporter activity

Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]


gamma-aminobutyric acid transmembrane transporter activity

Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA). [GOC:go_curators, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]


sphingosine transmembrane transporter activity


arbutin transmembrane transporter activity

Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other. [GOC:jl, GOC:mtg_transport, PMID:19965875]


D-galactarate transmembrane transporter activity


D-glucarate transmembrane transporter activity

Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of a membrane to the other. [GOC:jl, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]


D-galactonate transmembrane transporter activity

Enables the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of a membrane to the other. [GOC:jl, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]


D-glucuronate transmembrane transporter activity

Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other. [GOC:jl, GOC:jsg, GOC:mah, GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in). [GOC:ai, TC:2.A.1.1.6]


glucoside transmembrane transporter activity

Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue. [GOC:jl, GOC:mtg_transport, ISBN:0815340729]


salicin transmembrane transporter activity

Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other. [GOC:jl, GOC:mtg_transport, ISBN:0815340729]


arabinose transmembrane transporter activity

Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other. [GOC:jl, GOC:mtg_transport, ISBN:0815340729]


arabinan transmembrane transporter activity

Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other. [GOC:jl, GOC:mtg_transport, ISBN:0815340729]


L-arabinose transmembrane transporter activity

Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc. [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]


OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out). [TC:2.A.1.2.15]


D-ribose transmembrane transporter activity

Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12. [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]


D-xylose transmembrane transporter activity

Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides. [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729]


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in). [TC:2.A.1.1.3]


dextrin transmembrane transporter activity

Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other. [GOC:jl, GOC:vk]


maltodextrin transmembrane transporter activity

Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of a membrane to the other. [GOC:jl, PMID:15034926]


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out). [PMID:10735876]


concentrative nucleoside transporter activity

nucleoside transmembrane transporter activity, against a concentration gradient

Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient. [GOC:tb]


equilibrative nucleoside transporter activity

nucleoside transmembrane transporter activity, down a concentration gradient

Enables the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient. [PMID:10353709, PMID:11749958, PMID:12446811]


3-phenylpropionate acid transporter activity

3-phenylpropionic acid transmembrane transporter activity

Enables the transfer of 3-phenylpropionic acid from one side of a membrane to the other. [GOC:jl]


pyruvate transmembrane transporter activity

Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other. [GOC:ai]


high affinity copper ion transmembrane transporter activity

high affinity copper transporter activity

high-affinity copper ion transmembrane transporter activity

Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. [TC:9.A.11.1.1]


low affinity iron ion transmembrane transporter activity

low-affinity ferric iron ion transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. [TC:9.A.9.1.1]


potassium ion transmembrane transporter activity

Enables the transfer of potassium ions (K+) from one side of a membrane to the other. [GOC:ai]


silver ion transmembrane transporter activity

Enables the transfer of silver (Ag) ions from one side of a membrane to the other. [GOC:ai]


sodium ion transmembrane transporter activity

Enables the transfer of sodium ions (Na+) from one side of a membrane to the other. [GOC:ai, GOC:BHF]


molybdenum ion transmembrane transporter activity

Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other. [GOC:jl, ISBN:0198506732]


transition metal ion transmembrane transporter activity

Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. [ISBN:0198506732]


xanthine transmembrane transporter activity

Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids. [GOC:jl]


adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity

3'-phosphoadenosine 5'-phosphosulphate transporter activity

3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity

Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other. [ISBN:0198506732]


carboxylic acid transmembrane transporter activity

Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). [GOC:ai]


group A colicin transmembrane transporter activity

Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other. [GOC:jl, GOC:mtg_transport, ISBN:0815340729, PMID:9171417]


enterobactin transporter activity
enterochelin transporter activity

enterobactin transmembrane transporter activity

Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other. [GOC:jl]


m-hydroxyphenylpropionic acid transporter activity

3-(3-hydroxyphenyl)propionic acid transporter activity

3-hydroxyphenylpropionic acid transporter activity

3-hydroxyphenylpropionic acid transmembrane transporter activity

Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other. [GOC:jl]


alkanesulphonate transporter activity
alkanesulfonate transporter activity

alkanesulfonate transmembrane transporter activity

Enables the directed movement of alkanesulfonate from one side of a membrane to the other. [GOC:jl]


A prolongation or process extending from a cell, e.g. a flagellum or axon. [GOC:jl, http://www.cogsci.princeton.edu/~wn/]


The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins. [GOC:cilia, GOC:krc, GOC:pde, ISBN:0824072820, PMID:19501669, PMID:26574505, PMID:6771304]


The membrane surrounding the outer segment of a vertebrate photoreceptor. [GOC:jl]


flagellin-based flagellum basal body, rod

bacterial-type flagellum basal body, rod

The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings. [GOC:cilia, GOC:mtg_sensu, PMID:10572114, PMID:11133968, PMID:12624192]


Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses. [GOC:jl, PMID:9705477]


A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. [GOC:go_curators]


A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication. [GOC:mlg]


A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. [GOC:md, GOC:mtg_sensu, ISBN:0135712254]


integral to outer membrane
integral to cell outer membrane
integral to external membrane

integral component of cell outer membrane

The component of the cell outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators, GOC:mtg_sensu]


An extracellular matrix part that consists of cross-linked glycoproteins. [GOC:mah, PMID:18508691, PMID:7048321]


Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan. [DOI:10.1016/j.foodchem.2008.11.065, GOC:jid]


The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls. [GOC:jid, PMID:11554482]


Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants. [GOC:jid]


An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens. [GOC:jid, GOC:mah, PMID:14503002, PMID:16662709]


An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier. [GOC:jid, GOC:mah, PMID:18440267, PMID:7706282]


The portion of the cytoskeleton that lies just beneath the plasma membrane. [GOC:mah]


The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane. [GOC:mah]


cortical microtubule, transverse to long axis

Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition. [ISBN:0943088399]


A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate. [ISBN:0198506732, PMID:14729689, PMID:15298919]


The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. [GOC:elh, PMID:20404130]


A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery. [GOC:hjd, GOC:mr, PMID:20622855, Wikipedia:XY_sex-determination_system]


The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA. [GOC:mah]


Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining. [PMID:1629244]


condensed chromosome, pericentric region


condensed nuclear chromosome kinetochore

A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. [GOC:elh]


condensed nuclear chromosome kinetochore-associated DASH complex location

A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the outer kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability. [GOC:jl, GOC:vw, PMID:11782438, PMID:11799062, PMID:15632076, PMID:15640796]


inner kinetochore of condensed chromosome

inner kinetochore of condensed nuclear chromosome

condensed nuclear chromosome inner kinetochore

The region of a kinetochore closest to centromeric DNA; in mammals the CREST antigens (CENP proteins) are found in this layer; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome. [GOC:clt, PMID:10619130, PMID:11483983]


outer kinetochore of condensed chromosome

outer kinetochore of condensed nuclear chromosome

condensed nuclear chromosome outer kinetochore

The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions. [GOC:clt, PMID:11483983]


The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres). [GOC:elh]


A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome. [GOC:elh]


A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome. [GOC:elh]


A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure. [GOC:elh]


A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex. [GOC:mah, PMID:12750522]


A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex. [GOC:mah, PMID:12750522]


A cohesin complex required for cohesion between sister chromatids that remain in the nucleus. [GOC:elh]


A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome. [GOC:elh]


Rad9-Hus1-Rad1 (9-1-1) clamp complex location

Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage. [PMID:12531008]


A structural unit of the synaptonemal complex found between the lateral elements. [GOC:elh]


A proteinaceous core found between sister chromatids during meiotic prophase. [GOC:elh]


A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them. [GOC:elh]


A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis. [GOC:elh, PMID:17268547, PMID:21795393]


Go, Ichi, Ni and San complex
GINS complex
GINS complex location

A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks. [GOC:rb, GOC:rn, PMID:12730134, PMID:16990792, PMID:17467990]


nuclear origin of replication recognition complex location

A multisubunit complex that is located at the replication origins of a chromosome in the nucleus. [GOC:elh]


A circular DNA molecule containing chloroplast encoded genes. [GOC:jl]


A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. [GOC:mah, GOC:vw]


The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females. [GOC:mah, GOC:mr, ISBN:0321000382, PMID:20622855]


The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females. [GOC:mah, GOC:mr, ISBN:0321000382, PMID:20622855]


beta-catenin destruction complex location

A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. [PMID:14600025]

beta-catenin degradation complex location


A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing. [GOC:clt, PMID:12730603]


von Hippel-Lindau tumor suppressor complex location

pVHL-elongin C-elongin B complex location

A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1. [GOC:mah, PMID:11865071]


The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites. [GOC:mah, GOC:mtg_sensu]


The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine. [GOC:jl]


The lipid bilayer surrounding a zymogen granule. [GOC:jl]


Vps fifty three tethering complex location

Golgi associated retrograde protein complex location

A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles. [GOC:clt, GOC:rn, PMID:10637310, PMID:12077354, PMID:12446664]


Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. [GOC:jl, PMID:17152095]


platelet dense body
platelet dense granule

Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins. [GOC:jl, PMID:10403682, PMID:11487378]


Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. [GOC:jl, ISBN:0721662544, PMID:7334549]


actomyosin complex location
actomyosin complex
actomyosin

Any complex of actin, myosin, and accessory proteins. [GOC:go_curators]


actomyosin, myosin complex location part

The myosin part of any complex of actin, myosin, and accessory proteins. [GOC:go_curators]


F-actin capping protein complex location

A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments. [GOC:go_curators, ISBN:0198599560]


1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex location

phosphoinositide 3-kinase complex, class IB

phosphatidylinositol 3-kinase complex location, class IB

phosphoinositide 3-kinase complex location, class IB

phosphatidylinositol 3-kinase complex, class IB

A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks. [PMID:9255069, PMID:9759495]


phosphatidylinositol 3-kinase complex location, class III

phosphoinositide 3-kinase complex location, class III

phosphoinositide 3-kinase complex, class III

phosphatidylinositol 3-kinase complex, class III

A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI). [GOC:bf, PMID:9255069]


A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core. [GOC:rb, Wikipedia:Proteasome]


proteasome core complex, alpha-subunit complex location

The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus. [GOC:jl, GOC:mtg_sensu, GOC:rb, PMID:10854779]


proteasome core complex, beta-subunit complex location

The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus. [GOC:jl, GOC:mtg_sensu, GOC:rb, PMID:10854779]


A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex. [GOC:mtg_sensu, GOC:rb]


proteasome regulatory particle, base subcomplex location

The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex. [GOC:mtg_sensu, GOC:rb]


proteasome regulatory particle, lid subcomplex location

The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex. [GOC:rb]


A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA. [GOC:jl, PMID:12045093]


The volume enclosed by the membranes of the rough endoplasmic reticulum. [GOC:jid]


SER lumen
smooth endoplasmic reticulum lumen

The volume enclosed by the membranes of the smooth endoplasmic reticulum. [GOC:jid]


extrinsic to endoplasmic reticulum membrane

extrinsic component of endoplasmic reticulum membrane

The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. [GOC:curators, GOC:dos]


GPI-anchor transamidase complex location

An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor. [GOC:jl, GOC:rb, PMID:12802054]


rough ER membrane
rough endoplasmic reticulum membrane

The lipid bilayer surrounding the rough endoplasmic reticulum. [GOC:mah]


MHC class I peptide loading complex location

A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. [GOC:jl, PMID:10631934]


A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum. [GOC:jl, PMID:10618487, PMID:10631934]


external leaflet of endosome membrane
external side of endosome membrane

The side (leaflet) of the endosome membrane that faces the cytoplasm. [GOC:lr]


A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species. [PMID:11577182]


glycine dehydrogenase complex location (decarboxylating)

glycine dehydrogenase complex (decarboxylating)

glycine dehydrogenase (decarboxylating) complex location

A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T. [GOC:mah, MetaCyc:GCVMULTI-CPLX]


Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C. [GOC:mah, PMID:2018775]


Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface. [GOC:jl, PMID:12179957]


The lipid bilayer surrounding a glycosome. [GOC:ai]


The lipid bilayer surrounding a hydrogenosome. [GOC:ai]


The lipid bilayer surrounding a glyoxysome. [GOC:ai]


A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction. [GOC:jl, PMID:11912051, PMID:9799531]


equatorial microtubule organising centre

equatorial microtubule organizing center

A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis. [PMID:11792817]


A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species. [GOC:clt, PMID:12134075]


A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe. [GOC:mtg_sensu, PMID:12134075, PMID:17021256]


mitochondrial intermembrane space protein transporter complex location

Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane. [PMID:12581629]


A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA. [GOC:jl, PMID:12045093]


The region of a mitochondrion to which the DNA is confined. [GOC:jl]


mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex location

A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus. [GOC:mtg_sensu, PMID:9395502]


mitochondrial respiratory chain supercomplex

The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. [GOC:curators, GOC:ecd, ISBN:0198547684]


mitochondrial respiratory chain complex I, membrane segment location

The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. [GOC:jid, GOC:mtg_sensu, ISBN:0716749556]


mitochondrial respiratory chain complex I, peripheral segment location

The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. [GOC:jid, GOC:mtg_sensu, ISBN:0716749556]


pre-sequence translocase-associated import motor

PAM complex location, Tim23 associated import motor

presequence translocase-associated import motor

PAM complex, Tim23 associated import motor

Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix. [GOC:mcc, GOC:vw, PMID:14517234, PMID:14638855]


TIM22 mitochondrial import inner membrane insertion complex location

mitochondrial inner membrane protein insertion complex location

A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12. [PMID:12191765, PMID:27554484]


mitochondrial proton-transporting ATP synthase, peripheral stalk

mitochondrial proton-transporting ATP synthase location, stator stalk

mitochondrial proton-transporting ATP synthase, stator stalk

One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. [GOC:mtg_sensu, PMID:10838056]


mitochondrial sorting and assembly machinery complex location

A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex. [PMID:12891361]


mitochondrial ribonuclease P complex location

A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species. The complex contains a single RNA molecule and a single protein molecule in yeast (PMID:12045094), but comprises three proteins and lacks an RNA component in humans. [GOC:mah, PMID:12045094, PMID:27187488]


Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix. [GOC:jl, GOC:mtg_muscle, ISBN:0198506732, PMID:6405378]


myrosinase complex location
thioglucosidase complex location
myrosinase complex

A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds. [PMID:10682349]


Protein translocon complex at the chloroplast outer membrane. [PMID:10646606]


The region of a chloroplast to which the DNA is confined. [GOC:jl]


A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner. [PMID:11842180]


Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope. [GOC:ai, GOC:mah]


cyanelle ribonuclease P complex location

A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules. [GOC:mah, PMID:12045094]


Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light. [GOC:jl, PMID:11532175]


The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. [GOC:jl, PMID:11532175]


The region of a plastid to which the DNA is confined. [GOC:jl]


The region of a proplastid to which the DNA is confined. [GOC:jl]


plastid-encoded plastid RNA polymerase complex A location

A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex. [PMID:10946105]


plastid-encoded plastid RNA polymerase complex B location

A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation. [PMID:10946105]


Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped. [GOC:jl, PMID:11217978]


Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis. [PMID:10567516]


Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis. [PMID:10567516]


A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. [GOC:krc, GOC:vw, PMID:12150911, PMID:12957375, PMID:15120992]


A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis. [PMID:12446671]


Noc4p-Nop14p complex location
Nop7 subcomplex
Nop7 complex
Nop7 complex location
Nop7 subcomplex location

A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis. [PMID:12446671]


A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis. [PMID:12446671]


A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins. [GOC:jl, PMID:7704047]


cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex location

A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. [GOC:mtg_sensu, PMID:9395502]


A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP. [GOC:jl, PMID:10671455]


Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase. [GOC:jl, http://www.ijp-online.com/archives/1969/001/02/r0000-0000tc.htm, PMID:12360215]


A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion. [PMID:10944212, PMID:23645161]


A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination. [ISBN:9780815341116, Wikipedia:Vacuole]


Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed. [GOC:jl, PMID:18046696, PMID:6337890]


DNA structures that are not part of a chromosome. [GOC:ai]


methionine adenosyltransferase complex location

A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules. [EC:2.5.1.6, GOC:jid, PMID:10644686]


apoB mRNA editing enzyme complex location

apolipoprotein B mRNA editing enzyme complex location

Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP). [PMID:10781591]


A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously. [PMID:10233976]


X chromosome located dosage compensation complex location, transcription activating

X chromosome located dosage compensation complex, transcription activating

An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster. [GOC:ma, GOC:mr, GOC:mtg_sensu, PMID:20622855, Wikipedia:XY_sex-determination_system]


Facilitates chromatin transcription complex location

A histone chaperone complex that facilitates nucleosome disassembly and reassembly upon DNA or RNA polymerase passage. [PMID:12934006, PMID:12934007, PMID:16678108, PMID:34731638]


The nucleus of a germ cell, a reproductive cell in multicellular organisms. [CL:0000586, GOC:go_curators]


The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity. [GOC:jl, GOC:mtg_sensu, PMID:19019837]


The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents. [GOC:jl, ISBN:0618254153]


The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents. [CL:0000537, GOC:jl]


The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo. [GOC:jl, GOC:mtg_sensu]


Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus. [ISBN:0618254153]


microspore mother cell nucleus
pollen mother cell nucleus

The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte. [GOC:tair_curators, ISBN:047186840X]


The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells. [GOC:tair_curators]


Rad50 complex location
Rad50 complex
MRX complex
Rad50-Rad32-Nbs1 complex
MRN complex location
Rad50-Rad32-Nbs1 complex location
Mre11 complex location
RMX complex location
RMX complex
RAD50-MRE11-NBN complex
RAD50-MRE11-NBN complex location
MRX complex location
MRN complex

Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. [GOC:mah, GOC:vw, PMID:11988766, PMID:17674145]


Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis. [PMID:12446671]


nucleolar ribonuclease P complex location

A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules. [GOC:mah, PMID:12045094]


BRM complex location
brahma complex location
BRM complex

A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof. [GOC:bhm, PMID:10809665, PMID:12482982]


A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit. [PMID:12196389]


Set1C
Set1C/COMPASS complex location
Set1/COMPASS complex location
COMPASS complex location
COMPASS complex
Set1/COMPASS complex

A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. [PMID:11687631, PMID:11742990, PMID:11805083, PMID:12488447, PMID:18508253, PMID:18838538]


A protein complex involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid2, Ash2, Jmj3, Snt2, and Sdc1. [PMID:12488447]


replication-coupling assembly factor complex location

A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4. [GOC:bf, PMID:10591219]


DNA-directed RNA polymerase II, core complex location

RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. [GOC:krc, GOC:mtg_sensu]


transcription factor TFIID complex location

A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters. [GOC:krc, GOC:mah, ISBN:0471953393, ISBN:0879695501]


histone methyltransferase complex location

A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins. [GOC:bf]


Extra Sex Combs/Enhancer of Zeste complex location

A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. [GOC:bf, GOC:sp, PMID:12408863, PMID:12408864, PMID:20064375]


A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs). [GOC:bf, PMID:10984439]


DSC1 transcription factor complex location

A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p. [GOC:mah, PMID:11206552, PMID:15838511, PMID:18160399, PMID:9343385]


Polycomb repressive complex location 1
PRC1 complex location
Polycomb repressive complex 1

A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling. [GOC:bf, PMID:10412979]


retrotransposon nucleocapsid
Virus-like particle

A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog. [GOC:clt, PMID:10861903]