The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side. [GOC:18629866, GOC:BHF]


The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves. [GOC:BHF, PMID:18629866]


The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves. [GOC:BHF, PMID:18629866]


The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves. [GOC:BHF, PMID:18629866]


The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. [DOI:10.1002/(SICI)1097-4687(199608)229:2<121::AID-JMOR1>3.0.CO;2-4]


The process in which bone which forms superficially in the organism are generated and organized. [PMID:12588850, PMID:15003632]


The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone. [PMID:21901110]


articular cartilage of joint development

The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure. [PMID:20097540, PMID:20679519]


temporomandibular joint articular cartilage development

The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure. [PMID:20679519]


hip joint articular cartilage development

The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure. [PMID:20097540]


mandibular condyle articular cartilage development

The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure. [PMID:20679519]


femoral head articular cartilage development

The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure. [PMID:20097540]


Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme. [PMID:14622403, PMID:23475961]


Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine. [PMID:17300176]


A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs. [PMID:29385397]


A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. [PMID:29385397]


negative regulation of transcription by glucose

Any process involving glucose that decreases the frequency, rate or extent or transcription. [PMID:11875061]


negative regulation of transcription from RNA polymerase II promoter by glucose

Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter. [PMID:11875061]


The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome. [PMID:19696886]


The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome. [PMID:19696886]


Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2. [EC:2.3.1.207, PMID:22753057]


calcium:proton antiporter complex location

A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in). [GOC:bhm, PMID:19098009, PMID:28645169]


ATP-dependent protein-DNA complex displacement activity

An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis. [PMID:18593879]


regulation of cardiac endothelial to mesenchymal transition

Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26857067]


positive regulation of cardiac endothelial to mesenchymal transition

Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26857067]


negative regulation of cardiac endothelial to mesenchymal transition

Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26857067]


regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity

Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. [PMID:23407971]


negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity

Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. [PMID:23407971]


The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences. [PMID:28784960]


mitochondrial respiratory chain complex IV pre-assembly complex location

A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components. [GOC:lnp, PMID:21068384]


regulation of small molecule metabolic process

Any process that modulates the rate, frequency or extent of a small molecule metabolic process. [GOC:vw]


positive regulation of small molecule metabolism

positive regulation of small molecule metabolic process

Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. [GOC:vw]


negative regulation of small molecule metabolism

negative regulation of small molecule metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. [GOC:vw]


mitotic cohesin dsDNA (leading strand) loading

The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle. [GOC:vw, PMID:29358048]


mitotic cohesin ssDNA (lagging strand) loading

The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle. [GOC:vw, PMID:29358048]


An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. [GOC:BHF, GOC:rph, PMID:21123617]


regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. [PMID:28007894]


negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process

Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. [PMID:28007894]


positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process

Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. [PMID:28007894]


Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. [PMID:20180778]


positive regulation of stress granule assembly

Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. [PMID:20180778]


negative regulation of stress granule assembly

Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. [PMID:20180778]


The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth. [PMID:17604854]


cichorine synthesis
cichorine anabolism
cichorine biosynthesis
cichorine formation

The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi. [PMID:24244835]


positive regulation of mitotic sister chromatid segregation

Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis. [PMID:12773390]


The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine. [PMID:27758894, PMID:28330936]


The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. [PMID:21335241]


The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. [PMID:21335241]


Binding to a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind. [PMID:20924116]


positive regulation of pheromone response MAPK cascade

Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade. [PMID:9315645]


A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells. [GOC:BHF, PMID:22571672, PMID:27129222, PMID:28516088]


An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses. [GOC:BHF, PMID:27129222, PMID:28516088]


positive regulation of meiotic sister chromatid arm separation

Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis. [PMID:20383139]


regulation of cardiac epithelial to mesenchymal transition

Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:BHF, GOC:rph, PMID:20951801]


positive regulation of cardiac epithelial to mesenchymal transition

Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:BHF, GOC:rph, PMID:20951801]


negative regulation of cardiac epithelial to mesenchymal transition

Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:BFH, GOC:rph, PMID:20951801]


Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine. [PMID:27758894, PMID:28330936]


Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+. [PMID:27758894, PMID:28330936]


Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O. [PMID:27758894, PMID:28330936]


A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations. [PMID:1733951]


The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. [GOC:jl]


inner membrane pellicle complex location

A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell. [GOC:mah, PMID:12456714]


The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol. [GOC:mah]


regulation of NFAT protein import into nucleus


inhibition of NFAT protein import into nucleus


negative regulation of NFAT protein import into nucleus


positive regulation of NFAT protein import into nucleus


RNA polymerase III hybrid type promoter transcriptional preinitiation complex assembly


RNA polymerase III type 1 promoter transcriptional preinitiation complex assembly


RNA polymerase III type 2 promoter transcriptional preinitiation complex assembly


RNA polymerase III type 3 promoter transcriptional preinitiation complex assembly


A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive. [GOC:bhm, GOC:mah, PMID:11779505, PMID:16322555, PMID:9670020]


SMAD2-SMAD3-SMAD4 protein complex location


response to high density lipoprotein particle


response to high density lipoprotein particle stimulus


response to low density lipoprotein particle

response to low-density lipoprotein particle


response to low-density lipoprotein particle stimulus


high-affinity zinc II ion transmembrane import


A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism. [GOC:pdt]


negative regulation of catenin import into nucleus


negative regulation of catenin protein nuclear translocation


protein-containing complex assembly involved in synapse maturation

The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation. [GOC:ascb_2009, GOC:dph, GOC:tb]


negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis


positive regulation of catenin import into nucleus


positive regulation of catenin protein nuclear translocation


N-methylnicotinate transmembrane transporter activity

Enables the transfer of N-methylnicotinate from one side of a membrane to the other. [GOC:tb]


lysine transmembrane import into vacuole


arginine transmembrane import into vacuole


integral component of pigment granule membrane

The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [PMID:11294610]


Any membrane that is part of a pigment granule. [PMID:11294610]


negative regulation of energy homeostasis


positive regulation of energy homeostasis


copper ion import across prospore membrane

The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol. [GOC:al, GOC:vw, PMID:21828039]


extrinsic to phagophore assembly site membrane

extrinsic component of phagophore assembly site membrane

The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. [GOC:mf]


phagophore assembly site peripheral membrane


integral to phagophore assembly site membrane


phagophore assembly site integral membrane protein


structural constituent of presynaptic actin cytoskeleton

The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton. [GOC:dos]


L-glutamate(1-) import across plasma membrane


The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane. [PMID:24745983]


K/Na hyperpolarization-activated channel 3 complex location


K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex location


K/Na hyperpolarization-activated cyclic nucleotide-gated channel 2 complex location


K/Na hyperpolarization-activated cyclic nucleotide-gated channel 4 complex location


potassium/sodium hyperpolarization-activated channel 3 complex location


potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 complex location


potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex location


potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer


potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 complex location


presynaptic actin cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton. [GOC:dos]


The actin cytoskeleton that is part of a presynapse. [GOC:dos]


The component of the synaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. [GOC:dos]


regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane

Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane. [GOC:dos]


intrinsic component of postsynaptic density membrane

The component of the postsynaptic density membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. [GOC:dos, GOC:mah]


extrinsic component of postsynaptic density membrane

The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. [GOC:autophagy, GOC:mf]


Any process that modulates the frequency, rate or extent of synaptic vesicle docking. [GOC:dos]


regulation of postsynaptic neurotransmitter receptor endocytosis

regulation of postsynaptic neurotransmitter receptor internalization

Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse. [GOC:ai]


regulation of postsynaptic specialization assembly

Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization. [GOC:dos]


regulation of postsynaptic density assembly

Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density. [GOC:dos]


regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane

Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles. [GOC:dos, PMID:20098723]


The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. [GOC:dos, GOC:dph]


A synapse that uses serotonin as a neurotransmitter. [GOC:dos]


The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. [GOC:dos, GOC:dph]


Cell-cell signaling in which the ligand is carried between cells by an exosome. [GOC:dos, PMID:19837038]


exosome mediated transynaptic signalling

Transynaptic signaling in which the ligand is carried across the synapse by an exosome. [GOC:dos, PMID:19837038]


regulation of recycling endosome localization within postsynapse

Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse. [GOC:dos, PMID:20098723]


regulation of modification of postsynaptic structure

Any process that modulates the frequency, rate or extent of modification of postsynaptic structure. [GOC:dos]


postsynaptic intermediate filament cytoskeleton

The intermediate filament cytoskeleton that is part of a postsynapse. [GOC:dos, PMID:25869803]


regulation of presynaptic dense core vesicle exocytosis

regulation of presynaptic dense core granule exocytosis

Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis. [GOC:dos, PMID:17881523]


regulation of neurotransmitter uptake into synaptic vesicle

regulation of synaptic vesicle neurotransmitter loading

regulation of neurotransmitter loading into synaptic vesicle

Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles. [GOC:dos, PMID:25176177]


Cell-cell signaling to or from a synapse, mediated by nitric oxide. [GOC:dos, PMID:19038221]


postsynaptic specialization membrane of symmetric synapse

The membrane component of the postsynaptic specialization of a symmetic synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. [GOC:dos]


postsynaptic specialization of symmetric synapse, intracellular component

A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses. [GOC:dos]


intrinsic component of postsynaptic specialization membrane of symmetric synapse

The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. [GOC:dos]


intrinsic to postsynaptic specialization membrane of symmetric synapse


integral component of postsynaptic specialization membrane of symmetric synapse

The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos]


extrinsic component of postsynaptic specialization membrane of symmetric synapse

The component of the postsynaptic specialization membrane of a symmetric synapse consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. [GOC:dos]


anchored component of postsynaptic specialization membrane of symmetric synapse

The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. [GOC:dos]


postsynaptic modulation of chemical synaptic transmission

Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. [GOC:dos]


presynaptic modulation of chemical synaptic transmission

Any process, acting in the presynapse that results in modulation of chemical synaptic transmission. [GOC:dos]


presynapse organisation
presynapse development

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse. [GOC:dos]


postsynapse organisation
postsynapse development

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse. [GOC:dos]


regulation of presynapse organisation
regulation of presynapse structure

Any process that modulates the physical form of a presynapse. [GOC:ai, GOC:dph, GOC:tb]


regulation of presynapse organization and biogenesis


regulation of postsynapse structure
regulation of postsynapse organisation

Any process that modulates the physical form of a postsynapse. [GOC:ai, GOC:dph, GOC:tb]


regulation of postsynapse organization and biogenesis


regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex

Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex. [GOC:dos, PMID:23209303]


regulation of trans-synaptic complex mediated retrograde trans-synaptic signaling


Any process that modulates the frequency, rate or extent of trans-synaptic signaling. [GOC:dos]


regulation of retrograde trans-synaptic signaling by endocanabinoid

Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid. [GOC:dos, PMID:15664177]


regulation of endocannabinoid-mediated retrograde trans-synaptic signaling


regulation of synapse adhesion between pre- and post-synapse

regulation of synaptic membrane adhesion

Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes. [GOC:dos]


zinc import into synaptic vesicle
Zn2+ import into synaptic vesicle

The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle. [PMID:9990090]


The action of a molecule that contributes to the structural integrity of a presynapse. [GOC:dos, PMID:23751498]


presynaptic intermediate filament cytoskeleton

The intermediate filament cytoskeleton that is part of a presynapse. [GOC:dos]


trans-synaptic signaling by BDNF, modulating synaptic transmission

Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse. [GOC:dos]


structural constituent of postsynaptic intermediate filament cytoskeleton

The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton. [GOC:dos]


postsynaptic intermediate filament cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton. [GOC:dos]


The action of a molecule that contributes to the structural integrity of a postsynapse. [GOC:dos]


A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton. [GOC:dos]


A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton. [GOC:dos]


The portion of the spectrin-associated cytoskeleton contained within the postsynapse. [GOC:dos, PMID:28576936]


postsynaptic spectrin-associated cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse. [GOC:dos, PMID:28576936]


trans-synaptic signaling by brain-derived neurotrophic factor

Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft. [GOC:dos]


cerebellar Golgi cell to granule cell synapse

A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell. [PMID:26134650]


intrinsic component of synaptic membrane

The component of the synaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. [GOC:dos, GOC:mah]


extrinsic component of synaptic membrane

The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. [GOC:dos]


A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall. [GOC:dos]


The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos]


thiosulfate transmembrane-transporting ATPase activity


cystathionine gamma-synthase activity (acts on O-phosphohomoserine)

Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate. [GOC:pz, PMID:5922970, PMID:9531508]


Catalysis of the reaction: fumarate + a menaquinol = succinate + a menaquinone. [GOC:pz, PMID:11850430, RHEA:27834]


Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid. [GOC:pz, RHEA:35951]


Catalysis of the reaction: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid + H2O + NAD = 3-dehydroquinate + ammonium + NADH + H+. [GOC:pz, RHEA:25956]


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene. [EC:4.2.3.-, GOC:pz]


Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+. [EC:1.21.3.-, GOC:pz]


Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = hydrogenphosphate + an L-1-phosphatidyl-inositol. [EC:3.1.3.-, GOC:pz]


5-diphosphoinositol pentakisphosphate 3-kinase activity

Catalysis of the reaction: 5-diphospho-1D-myo-inositol pentakisphosphate + ATP = 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP. [EC:2.7.4.24, GOC:pz]


Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+. [EC:1.1.1.365, GOC:pz]


Catalysis of the reaction: gamma-aminobutyric acid + L-histidine + ATP = H+ + homocarnosine + ADP + hydrogenphosphate. [EC:6.3.2.11, GOC:pz]


demethoxycurcumin synthase activity from feruloylacetyl-CoA

Catalysis of the reaction: feruloylacetyl-CoA + 4-coumaryl-CoA + H2O = demethoxycurcumin + 2 coenzyme A + carbon dioxide. [GOC:pz, RHEA:35139]


hypoxia-inducible factor-asparagine oxygenase activity

Catalysis of the reaction: 2-oxoglutarate + O2 + a hypoxia inducible factor (HIF) alpha subunit = succinate + carbon dioxide + a (3S)-3-hydroxy-L-asparagine-HIF alpha subunit. [GOC:pz, RHEA:54268]


peptidoglycan asparagine synthase activity

Catalysis of the reaction: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparatyl)-L-lysyl-D-alanyl-D-alanine + ammonium + ATP = H+ + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine + AMP + diphosphoric acid. [EC:6.3.1.-, GOC:pz]


gibberellin A34 carboxyl methyltransferase activity

Catalysis of the reaction: gibberellin A34 + S-adenosyl-L-methionine = gibberellin A34 methyl ester + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz, RHEA:36127]


Catalysis of the reaction: 4-dihydrocoumaroyl-CoA + 3 malonyl-CoA + 3 H+ = phloretin + 4 coenzyme A + 3 carbon dioxide. [GOC:pz, PMID:20356611]


Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine. [EC:3.1.1.-, GOC:pz]


[chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity

Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate. [EC:2.8.2.-, GOC:pz]


Catalysis of the reaction: tricetin + S-adenosyl-L-methionine = H+ + 3'-O-methyltricetin + S-adenosyl-L-homocysteine. [GOC:pz, RHEA:27493]


3'-O-methyltricetin O methyl transferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine + 3',5'-di-O-methyltricetin. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan. [EC:3.2.1.52, GOC:pz]


very-long-chain 3-hydroxyacyl-CoA dehydratase activity

Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain trans-2,3-dehydroacyl-CoA. [GOC:pz, RHEA:45812]


3-hydroxyacyl-CoA-acyl carrier protein transferase activity

Catalysis of the reaction: coenzyme A + a (3R)-3-hydroxyacyl-[acyl-carrier protein] = a (3R)-3-hydroxyacyl-CoA + a holo-[acyl-carrier protein]. [EC:2.4.1.-, GOC:pz]


L-idonate 5-dehydrogenase activity (NAD-dependent)

Catalysis of the reaction: L-idonate + NAD = 5-dehydro-D-gluconate + NADH + H+. [GOC:pz, RHEA:21172]


nitric oxide reductase activity (NAD(P)H-dependent) activity

Catalysis of the reaction: dinitrogen oxide + H2O + NAD(P) = 2 nitric oxide + H+ + NAD(P)H. [EC:1.7.1.14, GOC:pz]


Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate. [GOC:pz, RHEA:33159]


Catalysis of the reaction: UDP-alpha-D-glucose + cholesterol = UDP + cholesteryl beta-D-glucoside + H+. [GOC:pz, RHEA:61848]


Catalysis of the reaction: docosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 22-hydroxydocosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. [GOC:krc, GOC:pz, RHEA:40079]


unsaturated chondroitin disaccharide hydrolase activity

Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate. [EC:3.2.1.180, GOC:pz]


in-chain hydroxy fatty acyl-CoA synthetase activity

Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA. [EC:6.2.1.-, GOC:pz]


omega-hydroxy fatty acyl-CoA synthetase activity

Catalysis of the reaction: coenzyme A + ATP + an omega-hydroxy fatty acid = diphosphoric acid + AMP + a omega-hydroxyacyl-CoA. [EC:6.2.1.-, GOC:pz]


Catalysis of the reaction: ATP + H2O + a maltodextrin = AMP + hydrogenphosphate + a 6-phosphogluco-maltodextrin. [EC:2.7.9.4, GOC:pz]


6-phosphoglucan, water dikinase activity

Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin. [GOC:pz, RHEA:10256]


Catalysis of the reaction: n ATP + n H2O + starch = n AMP + n hydrogenphosphate + a 6-phosphogluco-amylopectin. [EC:2.7.9.4, GOC:pz]


phosphogluco-amylopectin water dikinase activity

Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-amylopectin = n AMP + n hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin. [EC:2.7.9.5, GOC:pz]


Catalysis of the reaction: 2 dihydrogen + NAD + 2 an oxidized ferredoxin = NADH + 3 H+ + 2 a reduced ferredoxin. [GOC:pz, RHEA:30279]


geraniol kinase activity (ATP-dependent) activity

Catalysis of the reaction: geraniol + ATP = geranyl monophosphate + ADP + H+. [EC:2.7.1.-, GOC:pz]


Catalysis of the reaction: (E,E)-geranylgeraniol + ATP = H+ + all-trans-geranyl-geranyl monophosphate + ADP. [GOC:pz, RHEA:61660]


Catalysis of the reaction: 2 a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 2-monoglyceride. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine. [EC:2.7.8.-, GOC:pz]


linear malto-oligosaccharide phosphorylase activity

Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide. [EC:2.4.1.1, GOC:pz]


cellulose 1,4-beta-cellobiosidase activity (reducing end)

Catalysis of the reaction: n H2O + a cellodextrin = n beta-cellobiose, releasing cellobiose from the reducing ends of the chains. [EC:3.2.1.176, GOC:pz]


Catalysis of the reaction: H2O + a 1,3-diglyceride = a monoglyceride + a fatty acid. [GOC:pz, PMID:21477884]


Catalysis of the reaction: H2O + a 1,2-diacyl-sn-glycerol = a monoglyceride + a fatty acid. [GOC:pz, PMID:1477884]


homophytochelatin synthase activity (polymer-forming)

Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine. [EC:2.3.2.-, GOC:pz]


Catalysis of the reaction: 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose + H2O = N-acetyl-D-glucosamine + D-glucosamine. [EC:3.2.1.-, GOC:pz]


choline monooxygenase activity (NADP-dependent)

Catalysis of the reaction: choline + NADP = betaine aldehyde + NADPH + H+. [EC:1.1.1.-, GOC:pz]


Catalysis of the reaction: 1-deoxy-11-oxopentalenate + O2 + NADPH + H+ = pentalenolactone D + H2O + NADP. [GOC:pz, RHEA:34635]


Catalysis of the reaction: L-ornithinium(1+) = N(5)-acetyl-L-ornithine. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11-oxo-beta-amyrin + 2 H2O + NADP. [GOC:pz, RHEA:31719]


Catalysis of the reaction: cholesterol + NAD = cholest-5-en-3-one + NADH + H+. [GOC:pz, RHEA:35459]


Catalysis of the reaction: L-selenocysteine + O-phosphonato-L-homoserine = hydrogenphosphate + L-selenocystathionine. [EC:2.5.1.-, GOC:pz]


Catalysis of the reaction: linoleate + O2 = 9(R)-HPODE. [GOC:pz, RHEA:31691]


Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: 2-propylphenol + O2 + NADH + H+ = 3-propylcatechol + H2O + NAD. [GOC:pz]


Catalysis of the reaction: 2-isopropylphenol + O2 + NADH + H+ = 3-isopropylcatechol + H2O + NAD. [GOC:pz, RHEA:63520]


Catalysis of the reaction: 2-hydroxy-6-oxo-nona-2,4-dienoate + H2O = butyrate + 2-oxopent-4-enoate + H+. [EC:3.7.1.-, GOC:pz]


Catalysis of the reaction: H2O + a 3-oxoacyl-CoA = H+ + coenzyme A + a 3-oxoacid. [EC:3.1.2.-, GOC:pz]


Catalysis of the reaction: H+ + a 3-oxoacid = carbon dioxide + a methylketone. [EC:4.1.1.-, GOC:pz]


Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: malonyl-CoA + 3 H+ + a heptodecanoyl-[acp] = octadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: malonyl-CoA + 3 H+ + a stearoyl-[acp] = nonadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein]. [EC:2.3.1.-, GOC:pz]


gamma-aminobutyrate transaminase (glyoxylate dependent) activity

Catalysis of the reaction: gamma-aminobutyric acid + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine. [EC:2.6.1.96, GOC:pz]


Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate. [EC:2.7.4.-, GOC:pz]


Catalysis of the reaction: 11-cis-retinol + NADP = 11-cis-retinal + NADPH + H+. [GOC:pz, RHEA:54912]


Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O. [GOC:pz, PMID:15178487]


Catalysis of the reaction: 7-beta-hydroxytaxusin + NADPH + O2 + H+ = 2alpha, 7-beta-dihydroxytaxusin + NADP + H2O. [EC:1.14.13.-, GOC:pz]


steviol 13-O glucosyltransferase activity

Catalysis of the reaction: steviol + UDP-alpha-D-glucose = steviolmonoside + UDP + H+. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP + H+. [EC:2.4.1.-, GOC:pz]


steviolbioside glucosyltransferase activity (stevioside forming)

Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP + H+. [EC:2.4.1.-, GOC:pz]


steviolbioside glucosyltransferase activity (rebaudioside B forming)

Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+. [EC:2.4.1.-, GOC:pz]


stevioside glucosyltransferase activity (rebaudioside A forming)

Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = rebaudioside A + UDP + H+. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: 2-phenylethanol + NADP = phenylacetaldehyde + NADPH + H+. [EC:1.1.1.-, GOC:pz]


Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A. [EC:2.3.1.224, GOC:pz]


Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol. [EC:1.3.1.94, GOC:pz]


2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity

Catalysis of the reaction: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside + H2O = 2-phenylethanol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose. [EC:3.2.1.149, GOC:pz]


Catalysis of the reaction: luteolin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = luteolin-7-O-gentiobioside + UDP + H+. [EC:2.4.1.-, GOC:pz]


sn-2-glycerol-3-phosphate omega-OH-C22:0-CoA acyl transferase activity

Catalysis of the reaction: omega-hydroxy-C22:0-CoA + sn-glycerol 3-phosphate = coenzyme A + 2-omega-hydroxy-C22:0-LPA. [EC:2.3.1.198, GOC:pz]


sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity

Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate. [EC:2.3.1.15, GOC:pz]


alpha-linolenate delta5 desaturase activity

Catalysis of the reaction: alpha-linolenate + O2 + a reduced electron acceptor = coniferonate + 2 H2O + an oxidized electron acceptor. [EC:1.14.19.-, GOC:pz]


anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity

Catalysis of the reaction: 4-coumaryl-CoA + H+ + an anthocyanidin-3-O-beta-D-glucoside = coenzyme A + H+ + an anthocyanidin-3-O-[6-O-(hydroxycinnamoyl)-beta-D-glucoside]. [GOC:pz, RHEA:35411]


Catalysis of the reaction: cyanidin + UDP-D-galactose = cyanidin 3-O-beta-D-galactoside betaine + UDP. [GOC:pz, RHEA:35631]


anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside. [GOC:pz, RHEA:35419]


8-oxo-deoxyadenine diphosphate phosphatase activity

Catalysis of the reaction: 8-oxo-dADP + H2O = 8-oxo-dAMP + hydrogenphosphate + H+. [EC:3.6.1.-, GOC:pz]


kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity

Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O. [EC:1.14.13.-, GOC:pz]


Catalysis of the reaction: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose. [GOC:pz, RHEA:36051]


Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate. [GOC:pz, RHEA:25840]


Catalysis of the reaction: dATP + 2 H2O = dAMP + 2 hydrogenphosphate + 2 H+. [EC:3.6.1.5, GOC:pz]


Catalysis of the reaction: dCTP + 2 H2O = dCMP + 2 hydrogenphosphate + 2 H+. [EC:3.6.1.5, GOC:pz]


Catalysis of the reaction: dUTP + 2 H2O = dUMP + 2 hydrogenphosphate + 2 H+. [EC:3.6.1.5, GOC:pz]


Catalysis of the reaction: dTTP + 2 H2O = dTMP + 2 hydrogenphosphate + 2 H+. [EC:3.6.1.5, GOC:pz]


Catalysis of the reaction: GTP + 2 H2O = GMP + 2 hydrogenphosphate + 2 H+. [EC:3.6.1.5, GOC:pz]


Catalysis of the reaction: dGTP + 2 H2O = dGMP + 2 hydrogenphosphate + 2 H+. [EC:3.6.1.5, GOC:pz]


Catalysis of the reaction: H2O + maltose = 2 glucose. [GOC:pz, PMID:16343940]


Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan. [GOC:pz, RHEA:41732]


Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose. [EC:2.4.1.25, GOC:pz]


Catalysis of the reaction: D-mannonate + NADP = NADPH + H+ + D-fructuronate. [GOC:pz, PMID:22925190]


Catalysis of the reaction: ADP alpha-D-glucoside + n a 1,4-alpha-D-glucan = ADP + n alpha-amylose. [EC:2.4.1.242, GOC:pz]


Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O. [EC:1.14.13.-, GOC:pz]


Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O. [EC:1.14.18.4, GOC:pz, PMID:8784737, PMID:9680976]


L-threonine O-3-phosphate phosphatase activity

Catalysis of the reaction: O-phospho-L-threonine + H2O = L-threonine + hydrogenphosphate. [EC:3.1.3.-, GOC:pz]


Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine + N1-methylguanine37 in tRNAPhe = L-methionine + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe. [GOC:pz, PMID:34184886, RHEA:36347]


Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe. [GOC:pz, RHEA:37899]


2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity

Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide. [GOC:pz, RHEA:36607]


Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H. [GOC:pz, PMID:10627048, PMID:24817117]


Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H. [GOC:pz, PMID:10627048]


D-mannose 6-phosphate 1-epimerase activity

Catalysis of the reaction: alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate. [EC:5.1.3.-, GOC:pz]


D-galactose 6-phosphate 1-epimerase activity

Catalysis of the reaction: alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate. [EC:5.1.3.-, GOC:pz]


Catalysis of the reaction: 2 H2O + a phosphatidylcholine = sn-glycero-3-phosphocholine + 2 H+ + 2 a carboxylate. [EC:3.1.1.5, GOC:pz]


lipoyl synthase activity (acting on glycine-cleavage complex H protein

Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. [EC:2.8.1.8, GOC:pz]


lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)

Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [pyruvate dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + 2 H+ + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. [EC:2.8.1.8, GOC:pz]


lipoyl synthase activity (acting on 2-oxoglutarate-dehydrogenase E2 protein

Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine + 2 5'-deoxyadenosine + 2 H+ + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier]. [EC:2.8.1.8, GOC:pz]


Catalysis of the reaction: S-adenosyl-L-methionine + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine + H+ + a [release factor]-N5-methyl-L-glutamine. [GOC:pz, RHEA:42896]


hydroxyproline O-arbinofuranose transferase activity

Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline = UDP + H+ + a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline. [EC:2.4.2.-, GOC:pz]


1-acyl dihydroxyacetone phosphate reductase activity

Catalysis of the reaction: 1-oleoylglycerone 3-phosphate + NADPH + H+ = 1-oleoyl-sn-glycero-3-phosphate + NADP. [EC:1.1.1.101, GOC:pz]


Catalysis of the reaction: keto-phenylpyruvate + L-tyrosine = L-phenylalanine + 3-(4-hydroxyphenyl)pyruvate. [EC:2.6.1.-, GOC:pz]


Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+. [EC:3.5.1.-, GOC:pz]


Catalysis of the reaction: H2O + a 3-oxo-myristoyl-[acp] = 3-oxo-myristate + H+ + a holo-[acyl-carrier protein]. [EC:3.1.2.-, GOC:pz]


Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein]. [EC:3.1.2.-, GOC:pz]


Catalysis of the reaction: H2O + a 3-oxo-palmitoyl-[acp] = 3-oxopalmitic acid + H+ + a holo-[acyl-carrier protein]. [EC:3.1.2.-, GOC:pz]


Catalysis of the reaction: 3-oxopalmitic acid + H+ = 2-pentadecanone + carbon dioxide. [EC:4.1.1.56, GOC:pz]


UDP-glucose: N-methylanthranilate glucosyltransferase activity

Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP. [EC:2.4.1.-, GOC:pz]


3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity

Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O. [EC:1.14.13.-, GOC:pz]


Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate = [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphoric acid. [EC:2.5.1.105, GOC:pz]


1-18:1-2-16:0-monogalactosyldiacylglycerol palmitoyl-lipid 7-desaturase activity

Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. [GOC:pz, PMID:15579662]


isopentenyladenine UDP glycosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine = H+ + 9-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP. [EC:2.4.1.-, GOC:pz]


cis-zeatin UDP glycosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP. [EC:2.4.1.-, GOC:pz]


trans-zeatin-O-glucoside UDP glycosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + O-beta-D-glucosyl-trans-zeatin = H+ + trans-zeatin-O-glucoside-7-N-glucoside + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 = aureusidin 6-O-beta-glucoside + H2O + H+. [GOC:pz, RHEA:34203]


Catalysis of the reaction: beta-alanine + S-adenosyl-L-methionine = H+ + N-methyl-beta-alanine + S-adenosyl-L-homocysteine. [EC:2.1.1.49, GOC:pz]


Catalysis of the reaction: N-methyl-beta-alanine + S-adenosyl-L-methionine = H+ + N,N-dimethyl-beta-alanine + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: N,N-dimethyl-beta-alanine + S-adenosyl-L-methionine = H+ + beta-alanine betaine + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-inositol 3-phosphate = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H+. [GOC:pz, RHEA:26188]


Catalysis of the reaction: eugenol + S-adenosyl-L-methionine = H+ + O-methyleugenol + S-adenosyl-L-homocysteine. [EC:2.1.1.146, GOC:pz]


acetyl-coenzyme A:acetyl alcohol acetyltransferase activity

Catalysis of the reaction: benzyl alcohol + acetyl-CoA = benzyl acetate + coenzyme A. [EC:2.3.1.224, GOC:pz]


Catalysis of the reaction: O2 + 2 an ubiquinol = 2 H2O + 2 an ubiquinone. [GOC:pz, RHEA:30255]


gamma-hydroxybutyrate dehydrogenase activity (NAD(P)-dependent

Catalysis of the reaction: 4-hydroxybutyrate + NAD(P) = 4-oxobutanoate + H+ + NAD(P)H. [EC:1.1.1.-, GOC:pz]


Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+. [EC:2.4.1.-, GOC:pz]


UDP-glucose:curcumin monoglucoside glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: H+ + 24-methyldesmosterol + NADPH = campesterol + NADP. [EC:1.3.-.-, GOC:pz]


DIMBOA glucoside beta-D-glucosidase activity

Catalysis of the reaction: (2R)-DIMBOA glucoside + H2O = H+ + DIMBOA + beta-D-glucose. [EC:3.2.1.182, GOC:pz]


Catalysis of the reaction: campest-4-en-3beta-ol + NAD = campest-4-en-3-one + NADH + H+. [EC:1.1.1.-, GOC:pz]


Catalysis of the reaction: (5alpha)-campestan-3-one + NADP = H+ + campest-4-en-3-one + NADPH. [EC:1.3.1.-, GOC:pz]


Catalysis of the reaction: H+ + 6-oxocampestanol + O2 + NADPH = cathasterone + H2O + NADP. [EC:1.14.13.-, GOC:pz]


D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity

Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP. [EC:2.7.1.-, GOC:pz]


Catalysis of the reaction: 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ATP = H+ + myo-inositol hexakisphosphate(12-) + ADP. [EC:2.7.1.140, GOC:pz]


Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor. [GOC:pz, PMID:17138693]


Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide. [GOC:pz, RHEA:35143]


all-trans-geranyl-geranyl diphosphate reductase activity

Catalysis of the reaction: H+ + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + NADPH = dihydrogeranylgeranyl-PP + NADP. [EC:1.3.1.-, GOC:pz]


Catalysis of the reaction: H+ + dihydrogeranylgeranyl-PP + NADPH = tetrahydrogeranylgeranyl-PP + NADP. [EC:1.3.1.-, GOC:pz]


Catalysis of the reaction: H+ + tetrahydrogeranylgeranyl-PP + NADPH = (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + NADP. [EC:1.3.1.-, GOC:pz]


geranylgeranyl-chlorophyll a reductase activity

Catalysis of the reaction: H+ + geranylgeranyl-chlorophyll a + NADPH = dihydrogeranylgeranyl-chlorophyll a + NADP. [EC:1.3.1.-, GOC:pz]


dihydrogeranylgeranyl-chlorophyll a reductase activity

Catalysis of the reaction: H+ + dihydrogeranylgeranyl-chlorophyll a + NADPH = tetrahydrogeranylgeranyl-chlorophyll a + NADP. [EC:1.3.1.-, GOC:pz]


tetrahydrogeranylgeranyl-chlorophyll a reductase activity

Catalysis of the reaction: chlorophyll a + NADP = tetrahydrogeranylgeranyl-chlorophyll a + NADPH + H+. [EC:1.3.1.-, GOC:pz]


Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+. [EC:2.4.1.186, GOC:pz]


1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)

Catalysis of the reaction: a glucosylated glycogenin = a glycogen. [EC:2.4.1.18, GOC:pz]


gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity

Catalysis of the reaction: gibberellin A15 (closed lactone form) + O2 + 2-oxoglutarate = gibberellin A37 (closed lactone form) + succinate + carbon dioxide. [EC:1.14.11.-, GOC:pz]


very-long-chain 3-ketoacyl-CoA synthase activity

Catalysis of the reaction: malonyl-CoA + a very-long-chain 2,3,4-saturated fatty acyl CoA = carbon dioxide + coenzyme A + a very-long-chain oxoacyl-CoA. [GOC:pz, RHEA:32727]


Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate. [EC:3.1.3.-, GOC:pz]


very-long-chain enoyl-CoA reductase activity

Catalysis of the reaction: NADP(3-) + a very-long-chain 2,3,4-saturated fatty acyl CoA <=> NADPH(4-) + H+ + a very-long-chain trans-2,3-dehydroacyl-CoA. [EC:1.3.1.93, GOC:pz]


6-deoxotyphasterol C-23 hydroxylase activity

Catalysis of the reaction: 6-deoxotyphasterol + O2 + a reduced electron acceptor = 6-deoxocastasterone + H2O + an oxidized electron acceptor. [EC:1.14.-.-, GOC:pz]


Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = UDP-alpha-D-apiose + carbon dioxide. [EC:4.1.1.-, GOC:pz]


Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine = 2 H+ + ponciretin + S-adenosyl-L-homocysteine. [EC:2.1.1.231, GOC:pz]


Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine. [EC:2.4.1.80, GOC:pz]


inositol phosphorylceramide synthase activity

Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol. [EC:2.7.1.-, GOC:pz]


sphingolipid very long chain fatty acid alpha-hydroxylase activity

Catalysis of the reaction: O2 + NADPH + H+ + a dihydroceramide = NADP + H2O + an alpha hydroxydihydroceramide. [EC:1.14.13.-, GOC:pz]


sphingolipid long-chain base 4-hydroxylase activity

Catalysis of the reaction: O2 + H+ + a dihydroceramide + NAD(P)H = H2O + a phytoceramide + NAD(P). [EC:1.14.13.-, GOC:pz]


Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate. [EC:2.7.1.138, GOC:pz]


Catalysis of the reaction: 2 H+ + isovaleryl-CoA + 3 malonyl-CoA = 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone + 4 coenzyme A + 3 carbon dioxide. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: H+ + epidihydrocholesterin + O2 + NADPH = (22alpha)-hydroxy-cholestanol + H2O + NADP. [EC:1.14.13.-, GOC:pz]


Catalysis of the reaction: beta-carotene + 2 O2 = 2 beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. [EC:1.13.11.-, GOC:pz]


Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. [EC:1.13.11.-, GOC:pz]


Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial. [GOC:pz, PMID:11316814]


Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin. [EC:1.14.19.2, GOC:pz]


Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-beta-D-caffeoylglucoside + coenzyme A. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: 4-coumaryl-CoA + pelargonidin 3-O-beta-D-glucoside = pelargonidin 3-O-beta-D-p-coumaroylglucoside + coenzyme A. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin = H+ + cyanidin 5-O-beta-D-glucoside + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: cyanidin 5-O-beta-D-glucoside + UDP-alpha-D-glucose = cyanin betaine + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 + 2 H+ = sulfuretin 6-glucoside + 2 H2O. [EC:1.21.3.6, GOC:pz]


Catalysis of the reaction: cinnamaldehyde + O2 + H2O = H+ + trans-cinnamate + hydrogen peroxide. [EC:1.2.3.9, GOC:pz]


Catalysis of the reaction: 1-naphthaldehyde + O2 + H2O = H+ + 1-naphthoate + hydrogen peroxide. [EC:1.2.3.9, GOC:pz]


Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate. Glucosinolates are a subclass of thioglucosides. [EC:3.2.1.147, GOC:pz]


Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + coenzyme A. [GOC:pz, RHEA:35515]


glutarate-semialdehyde dehydrogenase (NADP+) activity

Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+. [EC:1.2.1.-, GOC:pz]


UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-(p-coumaroyl)-glucoside = shisonin + UDP + H+. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine = H+ + isorhamnetin + S-adenosyl-L-homocysteine. [EC:2.1.1.42, GOC:pz]


Catalysis of the reaction: raffinose + D-galactosylononitol = stachyose + 1D-4-O-methyl-myo-inositol. [EC:2.4.1.67, GOC:pz]


Catalysis of the reaction: 2 raffinose <=> stachyose + sucrose. [GOC:pz, PMID:12060258]


1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity (SN2-16:3 forming)

Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. [GOC:pz, RHEA:46412]


1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming)

Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. [GOC:pz, RHEA:46756]


1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming)

Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor. [GOC:pz]


1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming)

Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:1-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. [GOC:pz, RHEA:46404]


1-18:2-2-18:1-phosphatidylcholine desaturase activity (SN2-18:2 forming)

Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor. [GOC:pz]


1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity (SN2-18:3 forming)

Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor = 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor. [GOC:pz]


Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid. [GOC:pz, RHEA:32559]


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = germacrene C + diphosphoric acid. [EC:4.2.3.60, GOC:pz]


alpha-ketoglutarate reductase activity (NADH-dependent)

Catalysis of the reaction: NAD + 2-hydroxyglutarate = H+ + 2-oxoglutarate + NADH. [EC:1.1.1.-, GOC:pz]


Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine = H+ + gramine + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = N-debenzoyl-(3'-RS)-2'-deoxytaxol + coenzyme A. [EC:2.3.1.-, GOC:pz]


Catalysis of the reaction: 3'-N-debenzoyltaxol + benzoyl-CoA = H+ + paclitaxel + coenzyme A. [EC:2.3.1.-, GOC:pz]


gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity

Catalysis of the reaction: 2 H+ + gibberellin A44 + 2-oxoglutarate + O2 = gibberellin A98 + succinate + carbon dioxide. [EC:1.14.11.-, GOC:pz]


Catalysis of the reaction: UDP-alpha-D-glucose + solanidine = H+ + gamma-chaconine + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: beta-chaconine + UDP-L-rhamnose = H+ + alpha-chaconine + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: beta-solanine + UDP-L-rhamnose = solanine + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: 1-propenylsulfenate = propanethiol S-oxide. [EC:5.3.-.-, GOC:pz]


Catalysis of the reaction: geranyl diphosphate + 4-hydroxybenzoic acid = 3-geranyl-4-hydroxybenzoate + diphosphoric acid. [GOC:pz, RHEA:27854]


(Z,E)-alpha- farnesene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid. [GOC:pz, PMID:17140613]


Catalysis of the reaction: H+ + (-)-medicarpin + NADPH = (+)-vestitol + NADP. [EC:1.3.1.-, GOC:pz]


Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate. [GOC:pz, RHEA:36779]


Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP. [GOC:pz, RHEA:28230]


Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenate = gypsogenate-28-beta-D-glucoside + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: UDP-alpha-D-glucose + 16-alpha-hydroxygypsogenate = 16-alpha-hydroxygypsogenate-28-beta-D-glucoside + UDP. [GOC:pz]


Catalysis of the reaction: orcinol + S-adenosyl-L-methionine = H+ + 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine. [EC:2.1.1.6, GOC:pz]


Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: phloroglucinol + S-adenosyl-L-methionine = H+ + 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: 3,5-dimethoxyphenol + S-adenosyl-L-methionine = H+ + 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine. [EC:2.1.1.-, GOC:pz]


Catalysis of the reaction: (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid = (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate. [GOC:pz, RHEA:28182]


Catalysis of the reaction: 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate + a glucosylated glucose acceptor = isoorientin + a non glucosylated glucose acceptor. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor. [GOC:pz, PMID:15220389]


Catalysis of the reaction: indole-3-acetate + L-valine + ATP = H+ + indole-3-acetyl-valine + AMP + diphosphoric acid. [EC:6.3.-.-, GOC:pz]


Catalysis of the reaction: indole-3-acetate + L-phenylalanine + ATP = H+ + indole-3-acetyl-phenylalanine + AMP + diphosphoric acid. [EC:6.3.-.-, GOC:pz]


Catalysis of the reaction: UDP-alpha-D-glucose + coniferyl aldehyde = H+ + coniferaldehyde glucoside + UDP. [EC:2.4.1.-, GOC:pz]


hypoglycin A gamma-glutamyl transpeptidase activity

Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B. [EC:2.3.2.2, GOC:pz]


Catalysis of the reaction: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine = menaquinol-7 + S-adenosyl-L-homocysteine + H+. [GOC:pz, PMID:1444716, PMID:9045837, RHEA:33255]


Catalysis of the reaction: UDP-alpha-D-glucose + sinapoyl aldehyde = H+ + sinapaldehyde glucoside + UDP. [EC:2.4.1.-, GOC:pz]


Catalysis of the reaction: 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P) = momilactone A + H+ + NAD(P)H. [GOC:pz, RHEA:25367]


Catalysis of the reaction: all-trans-4,4'-diapophytofluene + FAD + H+ = all-trans-4,4'-diapo-zeta-carotene + FADH2. [EC:1.3.8.-, GOC:pz]


Catalysis of the reaction: all-trans-4,4'-diapo-zeta-carotene + FAD + H+ = 4,4'-diaponeurosporene + FADH2. [EC:1.3.8.-, GOC:pz]


alcohol-forming fatty acyl-CoA reductase activity

Catalysis of the reaction: 2 NADPH + 2 H+ + a long-chain acyl-CoA = coenzyme A + 2 NADP + a long-chain alcohol. [EC:1.2.1.84, GOC:pz]


Catalysis of the reaction: icosanoyl-CoA + dodecan-1-ol = arachidoyl dodecanoate + coenzyme A. [EC:2.3.1.75, GOC:pz]


gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming)

Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 = gibberellin A110 + succinate + carbon dioxide. [EC:1.14.11.-, GOC:pz]


norsolorinate anthrone synthase activity

Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein]. [EC:2.3.1.221, GOC:pz]


Catalysis of the reaction: versicolorone + NADP = hydroxyversicolorone + NADPH. [GOC:pz, RHEA:35691]


nitrilotriacetate monooxygenase activity (FMN-dependent)

Catalysis of the reaction: nitrilotriacetate + O2 + FMNH2 = ammoniodiacetate + 2-oxo monocarboxylic acid anion + H2O + FMN. [EC:1.14.14.10, GOC:pz]


gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming)

Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide. [EC:1.14.11.-, GOC:pz]


Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide. [GOC:pz, PMID:14769790, RHEA:42336]


Catalysis of the reaction: ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP = ethyl-2-methylacetoacetate + NADPH + H+. [EC:1.1.1.-, GOC:pz]


Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate. [EC:2.4.2.43, GOC:pz]


Catalysis of the reaction: ATP + H+ + a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine = AMP + diphosphoric acid + a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine. [GOC:pz, PMID:12949933]


Catalysis of the reaction: FMN + H2O = riboflavin + hydrogenphosphate. [EC:3.1.3.-, GOC:pz]


Catalysis of the reaction: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide. [EC:4.2.2.-, GOC:pz]


ethylglyoxal reductase (NADH-dependent, hydroxyacetone-forming) activity

Catalysis of the reaction: H+ + methylglyoxal + NADH = hydroxyacetone + NAD. [EC:1.1.1.-, GOC:pz]


Catalysis of the reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate. [EC:5.1.1.-, GOC:pz]


beta-galactosidase activity (lactose isomerization)

Catalysis of the reaction: alpha-lactose = beta-(1->6)-galactobiose. [EC:5.4.1.-, GOC:pz]


Catalysis of the reaction: 3 H+ + methyl-1,4-benzoquinone + NADPH = methyl-1,4-benzoquinol + NADP. [EC:1.6.5.-, GOC:pz]


L-glyceraldehyde 3-phosphate reductase activity

Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH. [EC:1.1.1.-, GOC:pz]


Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor. [EC:2.8.4.4, GOC:pz]


Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor. [EC:1.1.5.-, GOC:pz]


Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin. [EC:2.8.1.-, GOC:pz]


ribosomal protein S6 glutamate-glutamate ligase activity

Catalysis of the reaction: L-glutamate + ATP + a [protein] C-terminal L-glutamate = ADP + hydrogenphosphate + H+ + a [protein] with C-terminal alpha-L-glutamate-alpha-L-glutamate. [EC:6.3.2.-, GOC:pz]


Catalysis of the reaction: L-methionine + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+. [EC:2.3.1.1, GOC:pz]


methyl beta-D-glucoside 6-phosphate glucohydrolase activity

Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol. [EC:3.2.1.86, GOC:pz]


inositol phosphorylceramide mannosyltransferase activity

Catalysis of the reaction: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1,6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H+. [GOC:pz, RHEA:64596]


4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity

Catalysis of the reaction: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 4alpha-methyl-5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H. [EC:1.1.1.170, GOC:pz]


4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity

Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H. [GOC:pz, RHEA:33447]


leukotriene C4 gamma-glutamyl transferase activity

Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma-L-glutamyl)-L-amino acid. [GOC:pz, PMID:1676842, PMID:9139674]


straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity

Catalysis of the reaction: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA = formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde. [EC:4.1.-.-, GOC:pz]


Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate. [GOC:pz, RHEA:37547]


cellular response to environmental stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus. [GOC:dos]


Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. [GOC:hjd]


Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. [GOC:hjd]


Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate. [GOC:hjd]


regulation of vesicle to membrane docking

Any process that modulates the frequency, rate or extent of vesicle docking. [PMID:22810233]


negative regulation of vesicle to membrane docking

Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking. [PMID:22810233]


positive regulation of vesicle to membrane docking

Any process that activates or increases the frequency, rate or extent of vesicle docking. [PMID:22810233]


Any process that modulates the onset of pupariation. [PMID:26510564]


Any process that stops, prevents or reduces the rate of onset of pupariation. [PMID:26510564]


Any process that activates or increases the frequency, rate or extent of onset of pupariation. [GOC:hjd]


Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala). [PMID:28362257]


A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. [GOC:aruk, GOC:bc, PMID:11585923]


The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. [GOC:aruk, GOC:bc, PMID:11585923.]


Mitochondrial tRNA pseudouridine(27/28) synthase


tRNA pseudouridylate synthase I activity


The collection of neuronal projections into a bundle of rods, known as a fascicle. [GOC:aruk, GOC:bc., PMID:12761826]


Catalysis of the reaction: an snRNA uridine = an snRNA pseudouridine. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. [PMID:28432181]


A type of synapse occurring between an axon and a dendritic spine. [PMID:15028757]


protein maturation by [2Fe-2S] cluster transfer

The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. [PMID:23615440]


protein maturation by [4Fe-4S] cluster transfer

The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. [PMID:23615440]


assembly of apicomedial cortex actomyosin

A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin. [PMID:28263180]


The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell. [PMID:23831726, PMID:28263180]


Any process that modulates the frequency, rate or extent of GABA-A receptor activity. [PMID:24044036]


positive regulation of GABA-A receptor activity

Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity. [PMID:24044036]


negative regulation of GABA-A receptor activity

Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity. [PMID:24044036]


The removal of a sugar or dicarbonyl from a glycated guanine. [PMID:28596309]


guanine deglycation, methylglyoxal removal

The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine. [PMID:28596309]


The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine. [PMID:28596309]


The modification of acetylpolyamine by the removal of acetyl groups. [PMID:28516954]


The modification of acetylspermadine by the removal of acetyl groups. [PMID:28516954]


regulation of cellular response to osmotic stress

Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress. [PMID:10398679]


Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide. [PMID:17242307]


tRNA U34 thiol-transferase activity
tRNA U34 2-thiouridylase

Catalysis of the reaction: uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+. [PMID:12549933, PMID:16387657]


mannosyl-oligosaccharide 1,2-alpha-mannosidase complex location

A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide. [GOC:bhm, PMID:21700223]


regulation of calcineurin-mediated signaling

Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling. [PMID:25081204]


negative regulation of calcineurin-mediated signaling

Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signalling. [PMID:25081204]


positive regulation of calcineurin-mediated signaling

Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling. [PMID:25081204]


Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA. [EC:2.1.1.206]


Any process that modulates the frequency, rate or extent of exit from mitosis. [GOC:al, PMID:11493649]


negative regulation of exit from meiosis

Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis. [GOC:al, PMID:11493649]


positive regulation of exit from meiosis

Any process that activates or increases the frequency, rate or extent of exit from meiosis. [GOC:al, PMID:11493649]


G-protein coupled folate receptor activity

G-protein coupled folic acid receptor activity

G protein-coupled folate receptor activity

Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. [PMID:26906738]


regulation of cobalamin metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. [PMID:29056341]


SUMO-protein ligase complex location
Sumoylation complex
SUMO transferase complex location
Sumoylation complex location
SUMO-protein ligase complex
SUMO transferase complex
SUMO ligase complex location

A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex. [PMID:16847351]


A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. [PMID:16847351]


regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. [GOC:hjd, PMID:19246489]


positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway

positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. [GOC:hjd, PMID:19246489]


negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway. [GOC:hjd, PMID:19246489]


dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity

Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. [GOC:ha, PMID:9597543]


aminoacyl-tRNA metabolism involved in translational fidelity

Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation. [GOC:hjd]


Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide. [PMID:29211711]


Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide. [PMID:29211711]


The modification of a histone by the addition of an succinyl group. [PMID:29211711]


Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone. [PMID:29211711]


Binding to a GATOR1 complex. [PMID:28199306]


The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol. [PMID:11136464]


The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol. [PMID:11136464]


nuclear membrane protein complex location

Any protein complex that is part of the nuclear membrane. [GOC:lnp, PMID:28356353]


nuclear membrane mitotic spindle pole body tethering complex location

mitotic nuclear membrane microtubule tethering complex location

A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane. [GOC:lnp, PMID:28356353]


regulation of cell adhesion involved in sprouting angiogenesis

Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24177325]


negative regulation of cell adhesion involved in sprouting angiogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24177325]


positive regulation of cell adhesion involved in sprouting angiogenesis

Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24177325]


The process of creating an elongation or projection from a glial cell. [GOC:ha, PMID:27131624]


glial cell projection elongation involved in axon ensheathment

The extension of a glial cell process or projection to wrap around an axon. [GOC:ha, PMID:27131624]


EDS1 disease-resistance complex location

A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes. [GOC:bhm, PMID:11574472, PMID:16040633]


nuclear membrane microtubule tethering complex location

A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules. [GOC:vw, PMID:19225124]


m7G(5')pppN diphosphatase complex location

DCS1 decapping scavenger complex location

A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide. [GOC:lnp, PMID:22985415, PMID:26258763]


Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus. [PMID:18006463]


Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus. [PMID:18006463]


A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate. [GOC:lnp, PMID:11553611]


Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde. [EC:4.1.2.53, GOC:imk, PMID:18754683]


Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene. [GOC:rjd, PMID:28696553]


A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum. [GOC:pga, PMID:19479899, PMID:26408931]


COPII vesicles tethering complex location

A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP65 and GM130 protein in H. sapiens and by Bug1 and Grh1 proteins in S. cerevisiae. [GOC:lnp, PMID:21482742, PMID:9628863]


regulation of glutamate receptor clustering

Any process that modulates the frequency, rate or extent of glutamate receptor clustering. [GOC:ha, PMID:28455372]


Catalysis of the hydrolysis of misacylated ala-tRNA(thr). [PMID:29410408]


regulation of (R)-mevalonic acid biosynthetic process

Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24296663]


negative regulation of (R)-mevalonic acid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24296663]


positive regulation of (R)-mevalonic acid biosynthetic process

Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:24296663]


vomitoxin formation
vomitoxin synthesis
vomitoxin anabolism
vomitoxin biosynthesis
DON biosynthetic process
deoxynivalenol biosynthetic process

The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats. [http://www.inchem.org/documents/jecfa/jecmono/v47je05.htm, https://doi.org/10.1007/BF03356188, PMID:19333439, PMID:25680507, PMID:25758923, PMID:8637056]


regulation of mitotic cohesin ssDNA (lagging strand) loading

Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. [PMID:29358048]


negative regulation of mitotic cohesin ssDNA (lagging strand) loading

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. [PMID:29358048]


positive regulation of mitotic cohesin ssDNA (lagging strand) loading

Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading. [PMID:29358048]


regulation of mitotic cohesin dsDNA (leading strand) loading

Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. [PMID:29358048]


negative regulation of mitotic cohesin dsDNA (leading strand) loading

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. [PMID:29358048]


positive regulation of mitotic cohesin dsDNA (leading strand) loading

Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading. [PMID:29358048]


acidocalcisome organization and biogenesis

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. [GO:0020022, PMID:25964650, PMID:26523947]


regulation of sterol biosynthetic process

Any process that modulates the frequency, rate or extent of a sterol biosynthetic process. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:16459310]


negative regulation of sterol biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:16459310]


positive regulation of sterol biosynthetic process

Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:16459310]


positive regulation of cobalamin metabolic process

Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process. [PMID:29056341]


negative regulation of cobalamin metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process. [PMID:29056341]


A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes. [GOC:ach, PMID:12204365, PMID:15521631, PMID:1845219, PMID:19288526, PMID:21818313, PMID:22425988]


The volume enclosed by the membranes of a reservosome. [GOC:ach, PMID:12204365, PMID:15521631, PMID:18452191, PMID:19288526, PMID:21818313, PMID:22425988]


A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome. [GOC:ach, PMID:12204365, PMID:15521631, PMID:18452191, PMID:19288526, PMID:21818313, PMID:22425988]


The lipid bilayer surrounding a reservosome. [GOC:ach, PMID:12204365, PMID:15521631, PMID:18452191, PMID:19288526, PMID:21818313, PMID:22425988]


negative regulation of store-operated calcium entry

Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23447642]


positive regulation of store-operated calcium entry

Any process that activates or increases the frequency, rate or extent of store-operated calcium entry. [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23447642]


protein localization to cytoplasmic mRNA processing body

Any process in which a protein is transported to, or maintained at, a P-body. [GOC:mah, PMID:28031482]


positive regulation of aggregation involved in sorocarp development

Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. [GOC:rjd, PMID:28257811]


negative regulation of aggregation involved in sorocarp development

Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug. [GOC:rjd, PMID:28257811]


positive regulation of elastin catabolic process

Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin. [GOC:BHF, GOC:BHF_miRNA, GOC:rph]


A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself. [GOC:bhm, PMID:16603771, PMID:21559432, PMID:23555303, PMID:26044184]


cap-independent translational initiation of linear mRNA

The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation. [GOC:kmv]